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$293+ Cheap flights from Santiago (SCL) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SFO
Jul 7 — Jul 141
Mon 7/7
Mon 7/14
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to San Francisco are usually found in March or October, booked 4 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Santiago to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 2, 2025.

Round-trip from

$573
(LATAM Airlines)

One-way from

$293
(Avianca)

Popular in

June

Cheapest in

March

Average price

$766
From Santiago Arturo Merino Benitez to San Francisco
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One-way flight from Santiago Arturo Merino Benitez to San Francisco
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Highest demand for flights based on searches. 9% potential increase in price ($71 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Santiago to San Francisco

Cheapest flights from Santiago to San Francisco
Explore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

This LATAM Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/159:40 pmSCL - SFO
2 stops21h 08mLATAM Airlines
Tue 9/308:55 amSFO - SCL
2 stops18h 05mLATAM Airlines
Deal found 7/2$573
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/182:30 pmSCL - SFO
2 stops36h 25mAvianca
Fri 8/222:20 pmSFO - SCL
2 stops29h 10mAvianca
Deal found 7/1$574
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1410:45 pmSCL - SFO
1 stop29h 13mUnited Airlines
Wed 12/313:00 pmSFO - SCL
1 stop36h 50mUnited Airlines
Deal found 6/30$578
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/268:40 pmSCL - SFO
1 stop18h 05mDelta
Sat 9/66:15 amSFO - SCL
2 stops20h 40mDelta
Deal found 7/2$580
This Booking.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2012:24 amSCL - SFO
1 stop26h 15mCopa Airlines
Tue 9/21:30 amSFO - SCL
1 stop24h 28mCopa Airlines
Deal found 6/30$590
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/29:55 pmSCL - SFO
1 stop28h 58mAmerican Airlines
Thu 10/3012:50 amSFO - SCL
1 stop27h 00mAmerican Airlines
Deal found 7/1$596
This LATAM Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/218:20 amSCL - SFO
1 stop31h 12mMultiple Airlines
Wed 9/311:35 amSFO - SCL
1 stop16h 25mMultiple Airlines
Deal found 7/1$612

Cheapflights Fare Finder

Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.

Fly from

Santiago

Fly to

San Francisco

Route

Depart

Return

Price

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 9/15

9:40 pm-2:48 pm

2 stops21h 08m

San Francisco

Tue 9/30

8:55 am-7:00 am

2 stops18h 05m

$573

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 8/18

2:30 pm-11:55 pm

2 stops36h 25m

San Francisco

Fri 8/22

2:20 pm-10:30 pm

2 stops29h 10m

$574

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Sun 9/7

11:05 pm-10:00 am

1 stop14h 55m

San Francisco

Tue 10/14

7:30 am-6:00 am

2 stops18h 30m

$578

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 8/20

12:24 am-11:39 pm

1 stop26h 15m

San Francisco

Tue 9/2

1:30 am-4:58 am

1 stop24h 28m

$590

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 8/21

8:20 am-12:32 pm

1 stop31h 12m

San Francisco

Wed 9/3

11:35 am-7:00 am

1 stop16h 25m

$612

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 8/14

9:55 pm-7:00 pm

1 stop24h 05m

San Francisco

Thu 8/21

12:15 pm-6:55 am

1 stop15h 40m

$638

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Tue 8/26

6:10 am-10:45 pm

2 stops19h 35m

$293

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Wed 9/10

4:40 pm-11:02 pm

3 stops34h 22m

$381

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Thu 7/31

10:45 pm-2:50 pm

1 stop19h 05m

$427

SantiagoSan Francisco

SCL - SFO

SCLSFO

Santiago Arturo Merino Benitez

Mon 8/18

2:26 am-11:39 pm

1 stop24h 13m

$448

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 12 results
1
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Best time to book a flight from Santiago to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Francisco

How far ahead should I book a flight from Santiago to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to San Francisco. Price data was last updated on June 27, 2025.

The price you pay for your flight from Santiago to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 4 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santiago to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $276). Flying from Santiago to San Francisco in June is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to SFO?

Find hourly flight availability from Santiago to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

It’s typically best to fly out from Santiago to San Francisco in the afternoon. Doing so could potentially save you 32% on the flight price compared to flying in the evening, which is usually more expensive.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated July 2, 2025.
Peruse reviews from past customers who have flown with Delta, LATAM Airlines, and Copa Airlines from Santiago to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,983 reviews

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,983 reviews
Delta
8.0
Very good
7,983 reviews

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
LATAM Airlines
7.5
Good
1,805 reviews
Delta
8.0
Very good
7,983 reviews

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.5
Good
1,465 reviews
Delta
8.0
Very good
7,983 reviews

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,983 reviews

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,363 reviews
Delta
8.0
Very good
7,983 reviews

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santiago to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santiago to San Francisco round-trip?

    Currently priced at $573, LATAM Airlines will fly you from Santiago to San Francisco and back. In addition to LATAM Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Avianca and Delta - these airlines can fly you to your destination from $574 and $578, respectively. LATAM Airlines is priced at 15% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Santiago to San Francisco one-way?

    One-way options have recently been found by users for as low as $293 on Avianca. Other airlines that offer cheap prices include LATAM Airlines from $427 and Copa Airlines from $448 one-way.

  • Can I find deals for flights from Santiago to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santiago to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Francisco.

  • Can I find deals for business class flights from Santiago to San Francisco?

    Yes. Cheapflights offers flight deals from Santiago to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $276). Flying from Santiago to San Francisco in June is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Roseville
Mountain View
South San Francisco
Livermore
Santa Cruz
Turlock
Manteca
Watsonville
Antioch
Hollister
Newark
Alameda
Hayward
Milpitas
Sunnyvale
Daly City
Campbell
Foster City
Capitola
Richmond

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from Santiago to San Francisco

Discover the top 5 airlines that operate flights from Santiago to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$513Average$838FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$518Average$627FlexibilityNo cancel feeOn-time70%
DeltaCheapest$533Average$719FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$538Average$698FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$612Average$876FlexibilityNo cancel feeOn-time71%

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