$309+ Cheap flights from Santiago (SCL) to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SFO
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Find cheap flights from Santiago to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santiago to San Francisco
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Last-minute
One-way
Cheapest flights from Santiago to San FranciscoExplore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from Santiago to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This Avianca deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:40 am -
2 stops18h 55m
Mon 9/72:15 pm -
2 stops21h 00m
Deal found 8/7![Avianca logo]()
$604
This Avianca deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:40 am -
2 stops20h 15m
Tue 9/811:55 pm -
2 stops20h 25m
Deal found 8/8![Avianca logo]()
$605
This Avianca deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:40 am -
2 stops20h 15m
Thu 10/1511:55 pm -
2 stops20h 25m
Deal found 8/5![Avianca logo]()
$608
This Avianca deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:40 am -
2 stops18h 55m
Sat 10/312:20 pm -
2 stops21h 00m
Deal found 8/5![Avianca logo]()
$612
This Avianca deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:40 am -
2 stops18h 55m
Sun 9/202:15 pm -
2 stops21h 00m
Deal found 8/6![Avianca logo]()
$621
This SmartFares deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:20 pm -
2 stops24h 30m
Thu 10/811:55 pm -
2 stops20h 25m
Deal found 8/5![Avianca logo]()
$629
This SmartFares deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:20 pm -
2 stops34h 15m
Mon 9/2811:55 pm -
2 stops20h 25m
Deal found 8/6![Avianca logo]()
$630
This SmartFares deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/134:20 pm -
2 stops24h 30m
Sat 9/1911:55 pm -
2 stops20h 25m
Deal found 8/9![Avianca logo]()
$632
This Justfly.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:30 am -
2 stops18h 53m
Mon 11/237:05 am -
1 stop17h 30m
Deal found 8/5![LATAM Airlines logo]()
$633
This SmartFares deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:40 am -
2 stops18h 55m
Tue 10/611:55 pm -
2 stops25h 50m
Deal found 8/8![Avianca logo]()
$636
This FlightHub deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:40 am -
2 stops33h 10m
Sat 8/2211:55 pm -
2 stops35h 20m
Deal found 8/6![Avianca logo]()
$638
This eDestinos deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:55 pm -
2 stops19h 54m
Thu 10/89:54 am -
1 stop15h 41m
Deal found 8/9![LATAM Airlines logo]()
$639
Best flights from Santiago to San FranciscoDiscover carefully curated flight deals from Santiago to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from Santiago to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:15 am -
1 stop22h 25m
Wed 10/148:21 pm -
1 stop27h 35m
Deal found 8/8![Copa Airlines logo]()
$663
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:55 pm -
1 stop18h 50m
Sat 11/76:00 am -
2 stops19h 55m
Deal found 8/7![Delta logo]()
$666
This Avianca deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:40 am -
2 stops42h 55m
Thu 9/172:15 pm -
2 stops21h 00m
Deal found 8/5![Avianca logo]()
$676
This LATAM Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:15 am -
2 stops33h 30m
Sat 10/1710:41 pm -
1 stop29h 14m
Deal found 8/5![Multiple Airlines logo]()
$751
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2911:55 pm -
1 stop24h 03m
Mon 10/127:05 am -
2 stops18h 30m
Deal found 8/8![Delta logo]()
$666
This Avianca deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:30 am -
2 stops25h 05m
Sat 10/102:30 am -
2 stops23h 15m
Deal found 8/6![Avianca logo]()
$678
This Copa Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:14 am -
1 stop22h 26m
Thu 10/88:21 pm -
1 stop27h 35m
Deal found 8/6![Copa Airlines logo]()
$706
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:55 pm -
1 stop19h 59m
Wed 10/146:00 am -
2 stops20h 55m
Deal found 8/8![Delta logo]()
$756
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:55 pm -
1 stop19h 59m
Wed 9/235:19 pm -
2 stops22h 26m
Deal found 8/5![Delta logo]()
$816
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:55 pm -
1 stop14h 58m
Thu 10/159:54 am -
1 stop15h 41m
Deal found 8/8![Delta logo]()
$836
Last-minute flights from Santiago to San FranciscoDiscover last-minute flight deals from Santiago to San Francisco. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to San Francisco. Data last updated August 10, 2026 and is based on user searches.
This SmartFares deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:20 pm -
2 stops24h 30m
Thu 10/811:55 pm -
2 stops20h 25m
Deal found 8/5![Avianca logo]()
$629
This FlightHub deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:40 am -
2 stops33h 10m
Sat 8/2211:55 pm -
2 stops35h 20m
Deal found 8/6![Avianca logo]()
$638
This Avianca deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:40 am -
2 stops20h 15m
Thu 10/1511:55 pm -
2 stops20h 25m
Deal found 8/5![Avianca logo]()
$608
This Avianca deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:40 am -
2 stops18h 55m
Mon 9/72:15 pm -
2 stops21h 00m
Deal found 8/7![Avianca logo]()
$604
This Avianca deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:40 am -
2 stops20h 15m
Tue 9/811:55 pm -
2 stops20h 25m
Deal found 8/8![Avianca logo]()
$605
This SmartFares deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/134:20 pm -
2 stops24h 30m
Sat 9/1911:55 pm -
2 stops20h 25m
Deal found 8/9![Avianca logo]()
$632
This Avianca deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:40 am -
2 stops18h 55m
Sun 9/202:15 pm -
2 stops21h 00m
Deal found 8/6![Avianca logo]()
$621
This oojo deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/164:20 pm -
2 stops24h 30m
Wed 9/232:15 pm -
2 stops30h 05m
Deal found 8/5![Avianca logo]()
$641
This SmartFares deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:20 pm -
2 stops34h 15m
Mon 9/2811:55 pm -
2 stops20h 25m
Deal found 8/6![Avianca logo]()
$630
This SmartFares deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:40 am -
2 stops18h 55m
Tue 10/611:55 pm -
2 stops25h 50m
Deal found 8/8![Avianca logo]()
$636
This eDestinos deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:55 pm -
2 stops19h 54m
Thu 10/89:54 am -
1 stop15h 41m
Deal found 8/9![LATAM Airlines logo]()
$639
One-way flights from Santiago to San FranciscoSearch for one-way flight options from Santiago to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from Santiago to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Avianca deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:40 am -
2 stops18h 55m
Deal found 8/6![Avianca logo]()
$309
This Avianca deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:40 am -
2 stops20h 15m
Deal found 8/6![Avianca logo]()
$311
This Avianca deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:40 am -
2 stops18h 55m
Deal found 8/7![Avianca logo]()
$314
This Avianca deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:40 am -
2 stops20h 15m
Deal found 8/7![Avianca logo]()
$319
This SmartFares deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:40 am -
2 stops33h 10m
Deal found 8/9![Avianca logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:40 am -
2 stops20h 15m
Deal found 8/9![Avianca logo]()
$333
This oojo deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:35 am -
2 stops25h 15m
Deal found 8/7![Avianca logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:00 am -
3 stops47h 14m
Deal found 8/9![Multiple Airlines logo]()
$340
This Flighttix deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:30 am -
2 stops25h 05m
Deal found 8/9![Avianca logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:40 am -
2 stops18h 55m
Deal found 8/9![Avianca logo]()
$346
Find flight deals from Santiago to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $604 (Avianca) |
One-way from | $309 (Avianca) |
Popular in | June |
Cheapest in | October |
Average price | $666 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Santiago to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Tue 10/6
5:15 am-11:40 pm
1 stop22h 25m
San Francisco
Wed 10/14
8:21 pm-3:56 am
1 stop27h 35m
$663
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Sat 10/31
11:55 pm-2:45 pm
1 stop18h 50m
San Francisco
Sat 11/7
6:00 am-6:55 am
2 stops19h 55m
$666
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Tue 9/29
11:55 pm-7:58 pm
1 stop24h 03m
San Francisco
Mon 10/12
7:05 am-5:35 am
2 stops18h 30m
$666
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Tue 9/1
6:40 am-10:35 pm
2 stops42h 55m
San Francisco
Thu 9/17
2:15 pm-3:15 pm
2 stops21h 00m
$676
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Sat 9/26
1:30 am-10:35 pm
2 stops25h 05m
San Francisco
Sat 10/10
2:30 am-5:45 am
2 stops23h 15m
$678
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Mon 9/28
5:14 am-11:40 pm
1 stop22h 26m
San Francisco
Thu 10/8
8:21 pm-3:56 am
1 stop27h 35m
$706
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Tue 10/13
8:15 am-1:45 pm
2 stops33h 30m
San Francisco
Sat 10/17
10:41 pm-7:55 am
1 stop29h 14m
$751
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Thu 10/1
11:55 pm-3:54 pm
1 stop19h 59m
San Francisco
Wed 10/14
6:00 am-6:55 am
2 stops20h 55m
$756
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Wed 9/16
11:55 pm-3:54 pm
1 stop19h 59m
San Francisco
Wed 9/23
5:19 pm-7:45 pm
2 stops22h 26m
$816
Quickest round-trip
SantiagoSan Francisco
SCL Santiago Arturo Merino Benitez - SFO San Francisco
SCLSFO
Santiago Arturo Merino Benitez
Mon 9/21
11:55 pm-10:53 am
1 stop14h 58m
San Francisco
Thu 10/15
9:54 am-5:35 am
1 stop15h 41m
$836
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Santiago to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to San Francisco in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*2 stars |
- Most accurate provider: When it comes to deals on Santiago-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santiago with our price prediction graph.
SCL-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to San Francisco
How far ahead should I book a flight from Santiago to San Francisco?
The price you pay for your flight from Santiago to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 6 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Santiago to San Francisco?
Currently, October is the cheapest month in which you can book a flight from Santiago to San Francisco (average of $555). Flying from Santiago to San Francisco in June is currently the most expensive (average of $787). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to San Francisco?
Airfare is typical for this route at the moment.
Santiago to San Francisco flights typically cost between $578 and $806 in August.The cheapest round-trip price found within the last 5 days was $604 on Avianca (Aug 25-Sep 7).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated August 10, 2026.
Peruse reviews from past customers who have flown with Delta,Copa Airlines, andLATAM Airlines from Santiago to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Santiago to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
San Bruno
Fairfield
Emeryville
Roseville
Burlingame
Rancho Cordova
Vallejo
Cupertino
Newark
Hayward
San Ramon
Redwood City
San Carlos
Manteca
Turlock
San Lorenzo
Browse thousands of different options on Cheapflights for your next trip
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Santiago and San Francisco flights
Browse other Santiago and San Francisco flight options. Last updated on August 10, 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on August 10, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 10, 2026.
Top 6 airlines flying from Santiago to San Francisco
Discover the top 6 airlines that operate flights from Santiago to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$311 | Average$757 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$433 | Average$612 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$481 | Average$705 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$501 | Average$662 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$509 | Average$735 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$571 | Average$710 | FlexibilityNo cancel fee | On-time69% |