San Francisco

$233+ Cheap flights from South America to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
BOG — SFO
May 24 — May 311
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South America to San Francisco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South America to San Francisco

Cheapest flights from South America to San Francisco
Explore the most affordable flight options available from South America to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:21 pm
BOG
-
SFO
1 stop13h 38m
American Airlines
Mon 6/89:50 pm
SFO
-
BOG
1 stop11h 30m
American Airlines
Deal found 4/23$377
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:45 pm
BOG
-
SFO
2 stops14h 52m
American Airlines
Wed 9/235:30 am
SFO
-
BOG
1 stop15h 27m
American Airlines
Deal found 4/24$381
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:45 pm
BOG
-
SFO
1 stop24h 36m
American Airlines
Tue 9/298:49 am
SFO
-
BOG
1 stop12h 08m
American Airlines
Deal found 4/23$385
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:45 pm
BOG
-
SFO
1 stop21h 31m
American Airlines
Wed 9/306:36 am
SFO
-
BOG
1 stop14h 21m
American Airlines
Deal found 4/20$390
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:10 pm
BOG
-
SFO
1 stop12h 41m
American Airlines
Mon 9/286:36 am
SFO
-
BOG
1 stop14h 21m
American Airlines
Deal found 4/21$396
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:30 am
BOG
-
SFO
1 stop19h 29m
American Airlines
Wed 8/125:30 am
SFO
-
BOG
1 stop15h 04m
American Airlines
Deal found 4/22$398
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:30 am
BOG
-
SFO
1 stop20h 21m
American Airlines
Tue 8/2511:30 pm
SFO
-
BOG
1 stop21h 04m
American Airlines
Deal found 4/20$400
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:30 am
BOG
-
SFO
1 stop15h 15m
United Airlines
Tue 10/202:25 pm
SFO
-
BOG
1 stop12h 29m
United Airlines
Deal found 4/24$405
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:10 pm
BOG
-
SFO
1 stop22h 44m
American Airlines
Mon 6/111:29 pm
SFO
-
BOG
1 stop21h 09m
American Airlines
Deal found 4/24$414
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
MDE
-
SFO
1 stop20h 51m
American Airlines
Sun 8/239:05 am
SFO
-
MDE
1 stop12h 46m
American Airlines
Deal found 4/21$415
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:45 am
MDE
-
SFO
1 stop19h 14m
American Airlines
Sun 11/811:59 pm
SFO
-
MDE
1 stop20h 40m
American Airlines
Deal found 4/22$416
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
MDE
-
SFO
1 stop20h 51m
American Airlines
Mon 8/319:05 am
SFO
-
MDE
1 stop12h 46m
American Airlines
Deal found 4/19$418

Find flight deals from South America to San Francisco

Keep the following information in mind while searching for South America to San Francisco flight deals. Data was last updated April 24, 2026.

Round-trip from

$377
(American Airlines)

One-way from

$233
(American Airlines)

Popular in

December

Cheapest in

April

Average price

$464
From South America to San Francisco
One-way flight from South America to San Francisco
Highest demand for flights based on searches. 12% potential increase in price ($79 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from South America to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from South America to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BogotáSan Francisco

BOG - SFO

BOGSFO

Bogotá El Dorado

Wed 5/6

8:30 am-12:18 pm

1 stop29h 48m

San Francisco

Sun 5/17

5:00 am-4:54 am

1 stop21h 54m

$418

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Thu 5/7

9:45 am-11:59 pm

1 stop16h 14m

San Francisco

Mon 5/11

11:59 pm-9:10 pm

1 stop19h 11m

$422
Quickest round-trip

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Sat 5/2

9:45 am-7:05 pm

1 stop11h 20m

San Francisco

Sun 5/10

5:00 am-9:10 pm

1 stop14h 10m

$443

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Sat 5/2

9:15 am-11:40 pm

1 stop16h 25m

San Francisco

Sun 5/10

8:16 pm-9:40 am

1 stop11h 24m

$477

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Sun 5/10

9:15 am-11:40 pm

1 stop16h 25m

San Francisco

Thu 5/14

8:16 pm-2:15 pm

1 stop15h 59m

$477

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Thu 4/30

10:35 am-11:40 pm

1 stop15h 05m

San Francisco

Thu 5/14

1:12 am-2:45 pm

1 stop11h 33m

$477

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Fri 5/8

9:45 am-7:15 am

1 stop23h 30m

San Francisco

Sun 5/10

11:59 pm-9:10 pm

1 stop19h 11m

$497

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Fri 6/5

9:45 am-7:22 am

1 stop23h 37m

San Francisco

Sun 6/7

11:59 pm-9:10 pm

1 stop19h 11m

$499

BogotáSan Francisco

BOG - SFO

BOGSFO

Bogotá El Dorado

Tue 5/5

8:30 am-9:42 am

1 stop27h 12m

San Francisco

Sat 5/9

4:45 pm-7:20 pm

1 stop24h 35m

$510

BogotáSan Francisco

BOG - SFO

BOGSFO

Bogotá El Dorado

Thu 5/7

12:14 am-12:18 pm

1 stop14h 04m

San Francisco

Sun 5/10

12:45 am-4:54 am

1 stop26h 09m

$512

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from South America to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from South America with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South America to San Francisco

How far ahead should I book a flight from South America to San Francisco?

Booking 31 days in advance of your planned departure date is, on average, the best time to get cheap flights from South America to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from South America to San Francisco?

Currently, October is the cheapest month in which you can book a flight from South America to San Francisco (average of $541). Flying from South America to San Francisco in May is currently the most expensive (average of $706). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 24, 2026.
Read through reviews of airlines operating flights from South America to San Francisco, such as Copa Airlines,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.8

Food

6.8

Crew

8.1

Overall

7.5

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Entertainment

6.8

Food

6.8

Crew

8.1

Overall

7.5

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Entertainment

6.8

Food

6.8

Crew

8.1

Overall

7.5

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Entertainment

6.8

Food

6.8

Crew

8.1

Overall

7.5

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Entertainment

6.8

Food

6.8

Crew

8.1

Overall

7.5

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Entertainment

6.8

Food

6.8

Crew

8.1

Overall

7.5

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from South America to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Francisco from South America?

    San Francisco (SFO), located 11.0 mi from the city center, is the airport you fly into when you book flights from South America to San Francisco.

  • How long is the flight from South America to San Francisco?

    Departing from South America to San Francisco will take you 13h 21m. There are 3860 mi between South America and San Francisco. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from South America to San Francisco one-way?

    One-way options have recently been found by users for as low as $168 on Delta. Other airlines that offer cheap prices include Volaris from $211 and American Airlines from $214 one-way.

  • What are the most popular routes from South America to San Francisco?

  • Can I find deals for flights from South America to San Francisco that include hotel bookings?

    Yes. In addition to deals on South America to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South America to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South America to San Francisco.

  • Can I find deals for business class flights from South America to San Francisco?

    Yes. Cheapflights offers flight deals from South America to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South America to San Francisco?

    Currently, October is the cheapest month in which you can book a flight from South America to San Francisco (average of $541). Flying from South America to San Francisco in May is currently the most expensive (average of $706). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Rancho Cordova
San Bruno
Watsonville
San Ramon
Union City
Emeryville
Newark
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
San Lorenzo
Davis
Manteca
Elk Grove

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South America to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 8 airlines flying from South America to San Francisco

Discover the top 8 airlines that operate flights from South America to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$170Average$601FlexibilityNo cancel feeOn-time71%
DeltaCheapest$212Average$797FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$274Average$737FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$288Average$700FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$377Average$801FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$455Average$797FlexibilityNo cancel feeOn-time71%
AeromexicoCheapest$527Average$603FlexibilityNo cancel feeOn-timeN/A
GOLCheapest$832Average$903FlexibilityNo cancel feeOn-time74%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.