$273+ Cheap flights from South America to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
BOG — SFO
Jul 11 — Jul 181
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from South America to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South America to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from South America to San FranciscoExplore the most affordable flight options available from South America to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
Explore the most affordable flight options available from South America to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/151:30 am
BOG
- SFO
1 stop18h 42m
United Airlines
Thu 1/1412:45 am
SFO
- BOG
1 stop18h 50m
United Airlines
Deal found 6/7![United Airlines logo]()
$469
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:15 am
BOG
- SFO
1 stop11h 57m
United Airlines
Wed 1/205:00 am
SFO
- BOG
1 stop14h 35m
United Airlines
Deal found 6/6![United Airlines logo]()
$471
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:15 am
BOG
- SFO
1 stop11h 57m
United Airlines
Tue 1/1912:33 pm
SFO
- BOG
1 stop13h 37m
United Airlines
Deal found 6/8![United Airlines logo]()
$474
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:45 am
MDE
- SFO
1 stop26h 40m
United Airlines
Tue 6/166:54 pm
SFO
- MDE
1 stop24h 16m
United Airlines
Deal found 6/6![United Airlines logo]()
$499
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:45 am
MDE
- SFO
1 stop10h 44m
United Airlines
Tue 8/257:05 am
SFO
- MDE
1 stop12h 05m
United Airlines
Deal found 6/6![United Airlines logo]()
$511
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2411:55 pm
BOG
- SFO
1 stop12h 26m
American Airlines
Sat 1/237:00 am
SFO
- BOG
1 stop13h 30m
American Airlines
Deal found 6/8![American Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:00 am
BOG
- SFO
1 stop17h 59m
American Airlines
Tue 1/197:00 am
SFO
- BOG
2 stops13h 30m
American Airlines
Deal found 6/7![American Airlines logo]()
$532
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/148:15 am
BOG
- SFO
1 stop26h 05m
United Airlines
Sun 2/145:00 am
SFO
- BOG
1 stop14h 35m
United Airlines
Deal found 6/7![United Airlines logo]()
$543
This Faresmojo deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:25 pm
MDE
- SFO
1 stop11h 25m
JetBlue
Tue 8/2510:40 pm
SFO
- MDE
1 stop14h 05m
JetBlue
Deal found 6/9![JetBlue logo]()
$544
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:15 am
BOG
- SFO
1 stop26h 05m
United Airlines
Sun 1/311:59 pm
SFO
- BOG
1 stop19h 36m
United Airlines
Deal found 6/6![United Airlines logo]()
$545
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:15 am
BOG
- SFO
1 stop11h 57m
United Airlines
Mon 1/45:00 am
SFO
- BOG
1 stop14h 35m
United Airlines
Deal found 6/9![United Airlines logo]()
$546
This Faresmojo deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:59 am
UIO
- SFO
1 stop20h 25m
JetBlue
Sun 9/206:00 am
SFO
- UIO
1 stop10h 59m
JetBlue
Deal found 6/10![JetBlue logo]()
$546
Best flights from South America to San FranciscoDiscover carefully curated flight deals from South America to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
Discover carefully curated flight deals from South America to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:45 am
MDE
- SFO
1 stop10h 44m
United Airlines
Tue 8/257:05 am
SFO
- MDE
1 stop12h 05m
United Airlines
Deal found 6/7![United Airlines logo]()
$527
This Copa Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/272:56 am
SCL
- SFO
1 stop23h 44m
Copa Airlines
Mon 8/101:12 am
SFO
- SCL
1 stop22h 08m
Copa Airlines
Deal found 6/6![Copa Airlines logo]()
$568
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:40 pm
SCL
- SFO
1 stop26h 57m
Delta
Sun 10/257:30 am
SFO
- SCL
1 stop20h 10m
Delta
Deal found 6/8![Delta logo]()
$571
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
MDE
- SFO
1 stop16h 18m
American Airlines
Tue 8/259:35 pm
SFO
- MDE
1 stop20h 40m
American Airlines
Deal found 6/10![American Airlines logo]()
$648
This Avianca deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/262:15 pm
UIO
- SFO
2 stops35h 40m
Avianca
Sat 7/42:30 am
SFO
- UIO
2 stops32h 35m
Avianca
Deal found 6/6![Avianca logo]()
$662
This Despegar deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Despegar is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/211:25 pm
EZE
- SFO
1 stop17h 55m
Aeromexico
Sat 7/1111:53 pm
SFO
- EZE
1 stop17h 32m
Aeromexico
Deal found 6/6![Aeromexico logo]()
$1,050
This GOL deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:40 am
VCP
- SFO
2 stops41h 18m
GOL
Tue 11/241:07 pm
SFO
- VCP
2 stops39h 53m
GOL
Deal found 6/7![GOL logo]()
$1,076
This Copa Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/172:56 am
SCL
- SFO
1 stop23h 44m
Copa Airlines
Sun 8/238:21 pm
SFO
- SCL
1 stop20h 15m
Copa Airlines
Deal found 6/9![Copa Airlines logo]()
$568
This Azul deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Azul is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:55 pm
VCP
- SFO
1 stop27h 39m
Azul
Wed 9/308:30 am
SFO
- VCP
1 stop17h 00m
Azul
Deal found 6/9![Azul logo]()
$1,140
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:00 pm
SCL
- SFO
2 stops21h 31m
Delta
Sun 8/166:00 am
SFO
- SCL
2 stops20h 35m
Delta
Deal found 6/8![Delta logo]()
$571
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:25 am
UIO
- SFO
1 stop30h 49m
United Airlines
Thu 11/1211:59 pm
SFO
- UIO
1 stop21h 31m
United Airlines
Deal found 6/6![United Airlines logo]()
$602
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:43 am
SCL
- SFO
1 stop20h 17m
Copa Airlines
Sun 9/61:12 am
SFO
- SCL
1 stop19h 10m
Copa Airlines
Deal found 6/10![Copa Airlines logo]()
$568
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1711:00 pm
SCL
- SFO
2 stops19h 42m
Delta
Sun 8/236:00 am
SFO
- SCL
1 stop22h 15m
Delta
Deal found 6/7![Delta logo]()
$571
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:25 am
UIO
- SFO
1 stop18h 40m
United Airlines
Thu 7/911:59 pm
SFO
- UIO
1 stop21h 26m
United Airlines
Deal found 6/10![United Airlines logo]()
$602
This Avianca deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/272:10 pm
MDE
- SFO
1 stop10h 25m
Avianca
Sat 8/811:55 pm
SFO
- MDE
1 stop11h 15m
Avianca
Deal found 6/10![Avianca logo]()
$678
This Copa Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:14 am
SCL
- SFO
1 stop18h 45m
Copa Airlines
Mon 8/171:12 am
SFO
- SCL
1 stop25h 02m
Copa Airlines
Deal found 6/6![Copa Airlines logo]()
$568
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:00 pm
SCL
- SFO
2 stops23h 39m
Delta
Mon 9/711:54 am
SFO
- SCL
1 stop13h 41m
Delta
Deal found 6/8![Delta logo]()
$571
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:35 am
UIO
- SFO
1 stop20h 49m
United Airlines
Sat 10/2412:45 am
SFO
- UIO
1 stop20h 45m
United Airlines
Deal found 6/9![United Airlines logo]()
$611
This eDestinos deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/219:45 am
ASU
- SFO
3 stops53h 58m
Multiple Airlines
Sat 6/2711:59 pm
SFO
- ASU
3 stops52h 36m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$1,509
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:31 pm
UIO
- SFO
1 stop11h 09m
Copa Airlines
Tue 10/131:12 am
SFO
- UIO
1 stop10h 55m
Copa Airlines
Deal found 6/10![Copa Airlines logo]()
$576
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:59 am
UIO
- SFO
1 stop20h 50m
Delta
Mon 9/216:00 am
SFO
- UIO
1 stop10h 59m
Delta
Deal found 6/8![Delta logo]()
$602
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:30 am
BOG
- SFO
1 stop29h 44m
United Airlines
Wed 8/2611:59 pm
SFO
- BOG
1 stop26h 55m
United Airlines
Deal found 6/8![United Airlines logo]()
$615
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:14 am
BOG
- SFO
1 stop33h 08m
United Airlines
Thu 8/612:45 am
SFO
- BOG
1 stop26h 09m
United Airlines
Deal found 6/7![United Airlines logo]()
$616
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:00 am
BOG
- SFO
1 stop13h 10m
Copa Airlines
Thu 9/241:12 am
SFO
- BOG
1 stop20h 54m
Copa Airlines
Deal found 6/10![Copa Airlines logo]()
$618
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:15 am
BOG
- SFO
1 stop18h 49m
United Airlines
Wed 11/1111:59 pm
SFO
- BOG
1 stop19h 36m
United Airlines
Deal found 6/7![United Airlines logo]()
$616
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1812:08 pm
BOG
- SFO
1 stop13h 32m
Copa Airlines
Sun 9/201:12 am
SFO
- BOG
1 stop13h 55m
Copa Airlines
Deal found 6/10![Copa Airlines logo]()
$618
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:30 pm
LIM
- SFO
2 stops24h 44m
Delta
Tue 9/18:00 am
SFO
- LIM
2 stops19h 00m
Delta
Deal found 6/9![Delta logo]()
$728
This GOL deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:55 pm
CGH
- SFO
2 stops31h 12m
GOL
Tue 11/241:07 pm
SFO
- CGH
2 stops41h 08m
GOL
Deal found 6/7![GOL logo]()
$1,081
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2012:14 am
BOG
- SFO
1 stop33h 08m
United Airlines
Wed 8/512:45 am
SFO
- BOG
1 stop26h 09m
United Airlines
Deal found 6/6![United Airlines logo]()
$618
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:50 am
BOG
- SFO
1 stop16h 50m
Copa Airlines
Sun 9/278:21 pm
SFO
- BOG
1 stop11h 08m
Copa Airlines
Deal found 6/10![Copa Airlines logo]()
$618
Last-minute flights from South America to San FranciscoDiscover last-minute flight deals from South America to San Francisco. Data last updated June 11, 2026 and is based on user searches.
Discover last-minute flight deals from South America to San Francisco. Data last updated June 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/109:00 pm
SCL
- SFO
1 stop26h 17m
American Airlines
Wed 6/1712:01 pm
SFO
- SCL
1 stop16h 04m
American Airlines
Deal found 6/6![American Airlines logo]()
$576
This Avianca deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1510:10 am
UIO
- SFO
2 stops14h 25m
Avianca
Mon 6/292:15 pm
SFO
- UIO
1 stop10h 40m
Avianca
Deal found 6/9![Avianca logo]()
$577
This Flightnetwork deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:40 am
SCL
- SFO
2 stops42h 55m
Avianca
Tue 7/72:15 pm
SFO
- SCL
2 stops45h 00m
Avianca
Deal found 6/9![Avianca logo]()
$572
This Avianca deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:40 am
SCL
- SFO
2 stops20h 15m
Avianca
Tue 7/1411:55 pm
SFO
- SCL
2 stops20h 25m
Avianca
Deal found 6/10![Avianca logo]()
$567
This SmartFares deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:40 pm
SCL
- SFO
1 stop21h 10m
LATAM Airlines
Thu 7/169:20 am
SFO
- SCL
1 stop17h 15m
LATAM Airlines
Deal found 6/7![LATAM Airlines logo]()
$583
This Avianca deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:40 am
SCL
- SFO
2 stops20h 15m
Avianca
Tue 7/1411:55 pm
SFO
- SCL
2 stops20h 25m
Avianca
Deal found 6/8![Avianca logo]()
$561
This Avianca deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:45 am
UIO
- SFO
2 stops19h 50m
Avianca
Thu 7/232:15 pm
SFO
- UIO
2 stops16h 25m
Avianca
Deal found 6/10![Avianca logo]()
$576
This SmartFares deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/233:20 pm
SCL
- SFO
2 stops24h 30m
Avianca
Sat 11/281:20 pm
SFO
- SCL
2 stops21h 00m
Avianca
Deal found 6/6![Avianca logo]()
$582
This Copa Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/272:14 am
SCL
- SFO
1 stop24h 26m
Copa Airlines
Mon 8/101:12 am
SFO
- SCL
1 stop22h 48m
Copa Airlines
Deal found 6/9![Copa Airlines logo]()
$568
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:00 pm
SCL
- SFO
2 stops21h 31m
Delta
Tue 8/118:00 am
SFO
- SCL
1 stop20h 15m
Delta
Deal found 6/9![Delta logo]()
$571
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:00 pm
SCL
- SFO
2 stops19h 50m
American Airlines
Tue 8/116:36 am
SFO
- SCL
2 stops20h 49m
American Airlines
Deal found 6/9![American Airlines logo]()
$584
This oojo deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/303:20 pm
SCL
- SFO
2 stops24h 30m
Avianca
Thu 8/137:45 am
SFO
- SCL
3 stops27h 30m
Avianca
Deal found 6/9![Avianca logo]()
$574
One-way flights from South America to San FranciscoSearch for one-way flight options from South America to San Francisco. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
Search for one-way flight options from South America to San Francisco. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
This Avianca deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:40 am
SCL
- SFO
2 stops18h 55m
Avianca
Deal found 6/7![Avianca logo]()
$273
This Avianca deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:40 am
SCL
- SFO
2 stops20h 15m
Avianca
Deal found 6/6![Avianca logo]()
$277
This Avianca deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:40 am
SCL
- SFO
2 stops18h 55m
Avianca
Deal found 6/9![Avianca logo]()
$278
This Avianca deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:40 am
SCL
- SFO
2 stops20h 15m
Avianca
Deal found 6/8![Avianca logo]()
$279
This SmartFares deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:20 pm
SCL
- SFO
2 stops24h 30m
Avianca
Deal found 6/8![Avianca logo]()
$297
This SmartFares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:20 pm
SCL
- SFO
2 stops34h 15m
Avianca
Deal found 6/9![Avianca logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:40 am
SCL
- SFO
2 stops18h 55m
Avianca
Deal found 6/8![Avianca logo]()
$301
This oojo deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:20 pm
SCL
- SFO
2 stops34h 15m
Avianca
Deal found 6/10![Avianca logo]()
$304
This FlightHub deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/212:30 am
SCL
- SFO
2 stops39h 20m
Avianca
Deal found 6/10![Avianca logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:40 am
SCL
- SFO
2 stops18h 55m
Avianca
Deal found 6/10![Avianca logo]()
$308
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/139:45 am
MDE
- SFO
1 stop23h 37m
United Airlines
Deal found 6/7![United Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:50 am
BOG
- SFO
2 stops14h 48m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$326
Find flight deals from South America to San Francisco
Keep the following information in mind while searching for South America to San Francisco flight deals. Data was last updated June 11, 2026.
Round-trip from | $499 (United Airlines) |
|---|---|
One-way from | $273 (Avianca) |
Popular in | June |
Cheapest in | April |
Average price | $721 |
Cheapflights Fare Finder
Customize your flight search to find flights from South America to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
Use the filters below to find and compare flights from South America to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MedellínSan Francisco
MDE - SFO
MDESFO
Medellín Jose Maria Cordova Intl
Tue 8/18
9:45 am-6:29 pm
1 stop10h 44m
San Francisco
Tue 8/25
7:05 am-9:10 pm
1 stop12h 05m
$527
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Mon 7/27
2:56 am-11:40 pm
1 stop23h 44m
San Francisco
Mon 8/10
1:12 am-2:20 am
1 stop22h 08m
$568
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Mon 8/17
2:56 am-11:40 pm
1 stop23h 44m
San Francisco
Sun 8/23
8:21 pm-7:36 pm
1 stop20h 15m
$568
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Mon 8/24
12:43 am-6:00 pm
1 stop20h 17m
San Francisco
Sun 9/6
1:12 am-12:22 am
1 stop19h 10m
$568
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Tue 8/11
2:14 am-5:59 pm
1 stop18h 45m
San Francisco
Mon 8/17
1:12 am-5:14 am
1 stop25h 02m
$568
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Mon 10/19
8:40 pm-7:37 pm
1 stop26h 57m
San Francisco
Sun 10/25
7:30 am-7:40 am
1 stop20h 10m
$571
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Tue 7/28
11:00 pm-5:31 pm
2 stops21h 31m
San Francisco
Sun 8/16
6:00 am-5:35 am
2 stops20h 35m
$571
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Mon 8/17
11:00 pm-3:42 pm
2 stops19h 42m
San Francisco
Sun 8/23
6:00 am-7:15 am
1 stop22h 15m
$571
SantiagoSan Francisco
SCL - SFO
SCLSFO
Santiago Arturo Merino Benitez
Tue 8/25
11:00 pm-7:39 pm
2 stops23h 39m
San Francisco
Mon 9/7
11:54 am-5:35 am
1 stop13h 41m
$571
QuitoSan Francisco
UIO - SFO
UIOSFO
Quito Mariscal Sucr
Tue 10/6
2:31 pm-11:40 pm
1 stop11h 09m
San Francisco
Tue 10/13
1:12 am-2:07 pm
1 stop10h 55m
$576
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South America to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from South America with our price prediction graph.
BOG-SFO
MDE-SFO
UIO-SFO
SCL-SFO
EZE-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South America to San Francisco
0SA-SFO
BOG-SFO
MDE-SFO
UIO-SFO
SCL-SFO
What is the cheapest month to book a flight from South America to San Francisco?
Currently, October is the cheapest month in which you can book a flight from South America to San Francisco (average of $554). Flying from South America to San Francisco in May is currently the most expensive (average of $868). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from South America to San Francisco?
Booking 31 days in advance of your planned departure date is, on average, the best time to get cheap flights from South America to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated June 11, 2026.
Read through reviews of airlines operating flights from South America to San Francisco, such as Copa Airlines,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Food
6.9
Comfort
7.4
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Boarding
7.7
Food
6.9
Comfort
7.4
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Boarding
7.7
Food
6.9
Comfort
7.4
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Boarding
7.7
Food
6.9
Comfort
7.4
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Boarding
7.7
Food
6.9
Comfort
7.4
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Boarding
7.7
Food
6.9
Comfort
7.4
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Related info for your journey
Find useful and relevant information for your journey from South America to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
Roseville
Cupertino
Emeryville
Newark
San Bruno
Watsonville
San Ramon
Vacaville
San Carlos
Redwood City
Daly City
Sunnyvale
Turlock
Vallejo
San Lorenzo
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
San Francisco flight routes
Top destinations
Alternative routes for South America to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South America to San Francisco by cabin class
Find flights from South America to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South America and San Francisco flights
Browse other South America and San Francisco flight options. Last updated on June 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 11, 2026.
South America to San Francisco flights
Consider these flights traveling from South America to San Francisco.
Top 7 airlines flying from South America to San Francisco
Discover the top 7 airlines that operate flights from South America to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$212 | Average$806 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$254 | Average$622 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$274 | Average$753 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$288 | Average$699 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$405 | Average$808 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$455 | Average$799 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$832 | Average$903 | FlexibilityNo cancel fee | On-time74% |