San Francisco

$580+ Cheap flights from Santa Cruz de la Sierra (VVI) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/9. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SFO
lug 4 — lug 111
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Cheap flight deals from Santa Cruz de la Sierra to San Francisco

Cheapest flights from Santa Cruz de la Sierra to San Francisco
Explore the most affordable flight options available from Santa Cruz de la Sierra to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on giugno 4, 2026.

This Copa Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 7/271:12 am
VVI
-
SFO
1 stop25h 28m
Copa Airlines
gio 8/68:21 pm
SFO
-
VVI
1 stop28h 14m
Copa Airlines
Deal found 6/3$989
This Copa Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 8/151:12 am
VVI
-
SFO
1 stop25h 28m
Copa Airlines
dom 8/231:12 am
SFO
-
VVI
1 stop23h 23m
Copa Airlines
Deal found 6/2$1,009
This Copa Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 7/2711:47 am
VVI
-
SFO
1 stop14h 53m
Copa Airlines
gio 8/61:12 am
SFO
-
VVI
1 stop18h 28m
Copa Airlines
Deal found 6/3$1,028
This Copa Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 7/211:47 am
VVI
-
SFO
1 stop14h 53m
Copa Airlines
lun 8/241:12 am
SFO
-
VVI
1 stop18h 28m
Copa Airlines
Deal found 5/31$1,035
This United deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 10/213:35 am
VVI
-
SFO
2 stops21h 10m
Multiple Airlines
gio 11/125:00 am
SFO
-
VVI
2 stops41h 35m
Multiple Airlines
Deal found 6/4$1,050
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 9/2611:47 am
VVI
-
SFO
2 stops22h 37m
United Airlines
mar 9/2910:35 pm
SFO
-
VVI
2 stops21h 09m
United Airlines
Deal found 6/3$1,062
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 6/611:47 am
VVI
-
SFO
2 stops49h 12m
United Airlines
mer 6/1710:37 pm
SFO
-
VVI
2 stops45h 01m
United Airlines
Deal found 6/2$1,070
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 10/1911:47 am
VVI
-
SFO
2 stops25h 43m
United Airlines
mar 11/1012:45 am
SFO
-
VVI
2 stops17h 53m
United Airlines
Deal found 6/4$1,087
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 10/1311:47 am
VVI
-
SFO
2 stops39h 43m
United Airlines
ven 11/610:35 pm
SFO
-
VVI
2 stops44h 03m
United Airlines
Deal found 6/2$1,096
This oojo deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 10/1311:47 am
VVI
-
SFO
1 stop33h 23m
Copa Airlines
gio 11/512:33 am
SFO
-
VVI
1 stop23h 04m
Copa Airlines
Deal found 5/31$1,140

Find flight deals from Santa Cruz de la Sierra to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated giugno 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$989
(Copa Airlines)

One-way from

$580
(KAYAK)

Popular in

July

Cheapest in

May

Average price

$1,141
Provider with most accurate pricing for Santa Cruz de la Sierra Viru Viru Intl-San Francisco flight deals.
Provider most trusted by Cheapflights users for Santa Cruz de la Sierra Viru Viru Intl-San Francisco flights.
From Santa Cruz de la Sierra Viru Viru Intl to San Francisco
One-way flight from Santa Cruz de la Sierra Viru Viru Intl to San Francisco
Highest demand for flights based on searches. 14% potential increase in price ($150 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($26 potential savings vs. average RT price).
Average for round-trip flights in June 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated giugno 4, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

gio 8/27

1:12 am-11:40 pm

1 stop25h 28m

San Francisco

dom 9/27

1:12 am-3:38 am

1 stop23h 26m

$1,009
Quickest round-trip

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

lun 7/27

11:47 am-11:40 pm

1 stop14h 53m

San Francisco

mer 8/5

1:12 am-10:40 pm

1 stop18h 28m

$1,009

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

lun 7/27

11:47 am-11:40 pm

1 stop14h 53m

San Francisco

dom 8/9

1:12 am-10:40 pm

1 stop18h 28m

$1,028

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

sab 9/26

11:47 am-7:24 am

2 stops22h 37m

San Francisco

mar 9/29

10:35 pm-10:44 pm

2 stops21h 09m

$1,062

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

gio 10/22

11:47 am-9:18 am

2 stops24h 31m

San Francisco

lun 11/9

10:35 pm-10:38 pm

2 stops20h 03m

$1,087

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

gio 10/22

11:47 am-7:24 am

2 stops22h 37m

San Francisco

dom 11/15

11:59 pm-10:38 pm

2 stops18h 39m

$1,087

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

gio 10/22

11:47 am-11:20 am

2 stops26h 33m

San Francisco

mer 11/11

5:20 am-3:37 am

2 stops18h 17m

$1,087

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

mar 10/20

11:47 am-11:25 am

2 stops26h 38m

San Francisco

dom 11/15

11:59 pm-10:38 pm

2 stops18h 39m

$1,087

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

mar 10/20

11:47 am-11:20 am

2 stops26h 33m

San Francisco

mer 11/11

5:20 am-3:37 am

2 stops18h 17m

$1,087

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

mar 10/13

11:47 am-12:30 am

2 stops39h 43m

San Francisco

ven 11/6

10:35 pm-10:38 pm

2 stops44h 03m

$1,096

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/3

Showing 1-10 of 16 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Cruz de la Sierra-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Cruz de la Sierra to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to San Francisco

What is the cheapest month to book a flight from Santa Cruz de la Sierra to San Francisco?

Currently, May is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to San Francisco (average of $532). Flying from Santa Cruz de la Sierra to San Francisco in July is currently the most expensive (average of $1,180). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santa Cruz de la Sierra to San Francisco?

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated giugno 4, 2026.
Read reviews from past customers who have flown Copa Airlines and United Airlines from Santa Cruz de la Sierra to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.8

Comfort

7.4

Food

6.9

Crew

8.1

Boarding

7.7

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines

Entertainment

6.8

Comfort

7.4

Food

6.9

Crew

8.1

Boarding

7.7

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines

Entertainment

6.8

Comfort

7.4

Food

6.9

Crew

8.1

Boarding

7.7

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Santa Cruz de la Sierra to San Francisco?

    Copa Airlines and United Airlines can get you from Santa Cruz de la Sierra to San Francisco in just under 22h 37m. Your travel time can differ by up to 2h 51m. Airlines will cover a distance of 5414 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to San Francisco round-trip?

    According to our current data, United Airlines ($299), and Copa Airlines ($455) offers the cheapest pricing from Santa Cruz de la Sierra to San Francisco. United Airlines is 66% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santa Cruz de la Sierra to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to San Francisco.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to San Francisco?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to San Francisco?

    Currently, May is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to San Francisco (average of $532). Flying from Santa Cruz de la Sierra to San Francisco in July is currently the most expensive (average of $1,180). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
Cupertino
Emeryville
Newark
Watsonville
San Bruno
San Ramon
Vacaville
Roseville
San Carlos
Redwood City
Daly City
Turlock
Sunnyvale
Vallejo
San Lorenzo

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santa Cruz de la Sierra to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Santa Cruz de la Sierra to San Francisco

Discover the top 2 airlines that operate flights from Santa Cruz de la Sierra to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated giugno 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$299Average$837FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$455Average$1,102FlexibilityNo cancel feeOn-time70%

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