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$552+ Cheap flights from Santa Cruz de la Sierra (VVI) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SFO
Jul 18 — Jul 251
Sat 7/18
Sat 7/25
1 adult, Economy
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Cheap flight deals from Santa Cruz de la Sierra to San Francisco

Cheapest flights from Santa Cruz de la Sierra to San Francisco
Explore the most affordable flight options available from Santa Cruz de la Sierra to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.

This Copa Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:12 am
VVI
-
SFO
1 stop25h 28m
Copa Airlines
Thu 8/278:21 pm
SFO
-
VVI
1 stop23h 19m
Copa Airlines
Deal found 6/17$1,009
This Copa Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1611:47 am
VVI
-
SFO
1 stop14h 53m
Copa Airlines
Tue 8/251:12 am
SFO
-
VVI
1 stop23h 23m
Copa Airlines
Deal found 6/17$1,035
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2011:47 am
VVI
-
SFO
2 stops46h 35m
United Airlines
Tue 6/306:54 pm
SFO
-
VVI
2 stops29h 41m
United Airlines
Deal found 6/16$1,075
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:47 am
VVI
-
SFO
2 stops46h 51m
United Airlines
Thu 7/94:40 pm
SFO
-
VVI
2 stops27h 00m
United Airlines
Deal found 6/15$1,084
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:47 am
VVI
-
SFO
2 stops22h 37m
United Airlines
Sat 8/295:41 pm
SFO
-
VVI
2 stops25h 59m
United Airlines
Deal found 6/17$1,087
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1511:47 am
VVI
-
SFO
2 stops24h 43m
United Airlines
Wed 8/197:49 pm
SFO
-
VVI
2 stops23h 51m
United Airlines
Deal found 6/16$1,096
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1711:47 am
VVI
-
SFO
2 stops25h 42m
United Airlines
Tue 8/2511:30 pm
SFO
-
VVI
2 stops20h 10m
United Airlines
Deal found 6/17$1,104
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:55 am
VVI
-
SFO
2 stops25h 35m
United Airlines
Mon 11/239:30 pm
SFO
-
VVI
2 stops26h 07m
United Airlines
Deal found 6/16$1,110
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2511:47 am
VVI
-
SFO
2 stops46h 20m
United Airlines
Thu 7/3012:45 am
SFO
-
VVI
2 stops23h 50m
United Airlines
Deal found 6/17$1,113
This BusinessClass deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1811:47 am
VVI
-
SFO
2 stops39h 18m
Copa Airlines
Thu 6/256:54 pm
SFO
-
VVI
2 stops29h 37m
Copa Airlines
Deal found 6/16$1,118
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1611:47 am
VVI
-
SFO
1 stop14h 53m
Multiple Airlines
Wed 8/263:51 pm
SFO
-
VVI
2 stops27h 49m
Multiple Airlines
Deal found 6/17$1,134

Find flight deals from Santa Cruz de la Sierra to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$1,009
(Copa Airlines)

One-way from

$552
(Copa Airlines)

Popular in

June

Cheapest in

October

Average price

$1,341
Provider with most accurate pricing for Santa Cruz de la Sierra Viru Viru Intl-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Cruz de la Sierra Viru Viru Intl-San Francisco flights.
Search Deals
From Santa Cruz de la Sierra Viru Viru Intl to San Francisco
Search Deals
One-way flight from Santa Cruz de la Sierra Viru Viru Intl to San Francisco
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($232 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($33 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Sat 9/26

11:47 am-8:14 pm

2 stops35h 27m

San Francisco

Mon 9/28

10:40 pm-10:44 pm

2 stops45h 04m

$1,084

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 8/18

11:47 am-10:45 am

2 stops25h 58m

San Francisco

Thu 8/27

12:45 am-10:40 pm

2 stops18h 55m

$1,087

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Fri 8/14

11:47 am-10:29 am

2 stops25h 42m

San Francisco

Mon 8/24

7:05 am-3:35 am

2 stops17h 30m

$1,087

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 8/18

11:47 am-9:30 am

2 stops24h 43m

San Francisco

Tue 8/25

12:45 am-3:35 am

2 stops23h 50m

$1,087

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/15

11:47 am-9:30 am

2 stops24h 43m

San Francisco

Tue 8/18

12:45 am-3:35 am

2 stops23h 50m

$1,096

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/15

3:35 am-12:14 pm

2 stops35h 39m

San Francisco

Thu 8/27

4:40 pm-2:30 am

2 stops30h 50m

$1,102

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Mon 8/17

11:47 am-10:29 am

2 stops25h 42m

San Francisco

Sat 8/29

11:59 pm-10:40 pm

2 stops19h 41m

$1,104

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/2

11:49 am-12:04 am

2 stops16h 15m

San Francisco

Mon 11/23

6:30 pm-10:38 pm

2 stops24h 08m

$1,110

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/2

11:49 am-12:04 am

2 stops16h 15m

San Francisco

Tue 11/17

4:45 pm-10:38 pm

2 stops25h 53m

$1,110
Quickest round-trip

Santa Cruz de la SierraSan Francisco

VVI - SFO

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 7/14

11:47 am-11:40 pm

1 stop14h 53m

San Francisco

Thu 7/23

8:16 pm-10:40 pm

1 stop23h 24m

$1,137

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/16

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3
  • Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Cruz de la Sierra-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Cruz de la Sierra to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to San Francisco

What is the cheapest month to book a flight from Santa Cruz de la Sierra to San Francisco?

Currently, October is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to San Francisco (average of $768). Flying from Santa Cruz de la Sierra to San Francisco in June is currently the most expensive (average of $1,341). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santa Cruz de la Sierra to San Francisco?

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated June 18, 2026.
Read reviews from past customers who have flown Copa Airlines and United Airlines from Santa Cruz de la Sierra to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,567 reviews

Comfort

7.4

Overall

7.6

Boarding

7.8

Food

6.9

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines
Copa Airlines
7.6
Good
1,567 reviews
Copa Airlines
7.6
Good
1,567 reviews

Comfort

7.4

Overall

7.6

Boarding

7.8

Food

6.9

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines
United Airlines
7.4
Good
9,858 reviews
Copa Airlines
7.6
Good
1,567 reviews

Comfort

7.4

Overall

7.6

Boarding

7.8

Food

6.9

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2026

LIM - PTY

Fast boarding, polite and helpful staff. Lowest cost across all airlines

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to San Francisco?

    United Airlines can get you from Santa Cruz de la Sierra to San Francisco in just under 35h 27m. Your travel time can differ by up to . Airlines will cover a distance of 5414 mi.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to San Francisco round-trip?

    According to our current data, United Airlines ($299), and Copa Airlines ($455) offers the cheapest pricing from Santa Cruz de la Sierra to San Francisco. United Airlines is 69% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santa Cruz de la Sierra to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to San Francisco.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to San Francisco?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to San Francisco?

    Currently, October is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to San Francisco (average of $768). Flying from Santa Cruz de la Sierra to San Francisco in June is currently the most expensive (average of $1,341). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
Roseville
Cupertino
Emeryville
Newark
Watsonville
San Bruno
San Ramon
Vacaville
San Carlos
Redwood City
Daly City
Turlock
Sunnyvale
Vallejo
San Lorenzo

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Alternative routes for Santa Cruz de la Sierra to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Santa Cruz de la Sierra to San Francisco

Discover the top 2 airlines that operate flights from Santa Cruz de la Sierra to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$299Average$837FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$455Average$1,102FlexibilityNo cancel feeOn-time70%

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