San Francisco

$566+ Cheap flights from Santa Cruz de la Sierra (VVI) to San Francisco (SFO)

VVI — SFO
Dec 4 — Dec 111
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Cheap flight deals from Santa Cruz de la Sierra to San Francisco

Cheapest flights from Santa Cruz de la Sierra to San Francisco

Mon 11/161:08 am -
1 stop20h 17m
Sun 2/77:36 pm -
1 stop23h 06m
Deal found 10/31$1,015
Wed 12/211:34 am -
1 stop33h 51m
Wed 12/97:36 pm -
1 stop23h 12m
Deal found 11/3$1,041
Thu 12/2411:34 am -
2 stops23h 53m
Fri 1/156:36 pm -
2 stops24h 10m
Deal found 11/1$1,077
Tue 12/13:45 am -
2 stops36h 10m
Tue 12/81:30 am -
2 stops21h 10m
Deal found 11/3$1,083
Wed 12/233:45 am -
2 stops36h 10m
Tue 1/121:30 am -
2 stops21h 10m
Deal found 11/1$1,102
Mon 12/73:45 am -
2 stops36h 10m
Fri 1/811:00 pm -
2 stops23h 40m
Deal found 11/3$1,103
Thu 12/33:45 am -
2 stops21h 55m
Sat 12/51:30 am -
2 stops21h 10m
Deal found 11/1$1,120
Tue 12/13:45 am -
2 stops36h 10m
Sat 12/51:30 am -
2 stops21h 10m
Deal found 11/3$1,126

Find flight deals from Santa Cruz de la Sierra to San Francisco

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$983
(Copa Airlines)

One-way from

$566
(Copa Airlines)

Popular in

October

Cheapest in

November

Average price

$837
Provider with most accurate pricing for Santa Cruz de la Sierra Viru Viru Intl-San Francisco flight deals.
Provider most trusted by Cheapflights users for Santa Cruz de la Sierra Viru Viru Intl-San Francisco flights.
From Santa Cruz de la Sierra Viru Viru Intl to San Francisco
One-way flight from Santa Cruz de la Sierra Viru Viru Intl to San Francisco
High demand for flights, 0% potential price rise
Cheapest flight prices on average. 5% potential price decrease ($69 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santa Cruz de la Sierra to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 12/24

11:34 am-12:58 am

2 stops17h 24m

San Francisco

Wed 12/31

12:00 am-4:00 am

Nonstop0h 00m

$576

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 12/24

1:10 am-9:13 pm

2 stops24h 03m

San Francisco

Wed 12/31

12:00 am-4:00 am

Nonstop0h 00m

$605

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 12/24

1:10 am-11:17 pm

1 stop26h 07m

San Francisco

Wed 12/31

12:00 am-4:00 am

Nonstop0h 00m

$631

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Wed 1/20

1:14 am-5:25 pm

1 stop20h 11m

San Francisco

Wed 12/31

12:00 am-4:00 am

Nonstop0h 00m

$687

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/16

1:08 am-5:25 pm

1 stop20h 17m

San Francisco

Sun 2/7

7:36 pm-10:42 pm

1 stop23h 06m

$1,015

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/1

1:10 am-11:17 pm

1 stop26h 07m

San Francisco

Wed 12/9

7:36 pm-10:48 pm

1 stop23h 12m

$1,046

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 12/24

11:34 am-12:58 am

2 stops17h 24m

San Francisco

Mon 1/11

12:45 am-3:44 am

2 stops22h 59m

$1,077

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/1

3:45 am-11:55 am

2 stops36h 10m

San Francisco

Tue 12/8

1:30 am-2:40 am

2 stops21h 10m

$1,083

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Thu 12/3

3:45 am-9:40 pm

2 stops21h 55m

San Francisco

Sat 12/5

1:30 am-2:40 am

2 stops21h 10m

$1,121

Santa Cruz de la SierraSan Francisco

VVI Santa Cruz de la Sierra Viru Viru Intl - SFO San Francisco

VVISFO

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/1

3:45 am-11:55 am

2 stops36h 10m

San Francisco

Sat 12/5

1:30 am-2:40 am

2 stops21h 10m

$1,126

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 16 resultsSorted by cheapest first
1
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Compare providers for flights from Santa Cruz de la Sierra to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Cruz de la Sierra to San Francisco in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Cruz de la Sierra-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Cruz de la Sierra to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to San Francisco

How much does it cost to fly round-trip from Santa Cruz de la Sierra to San Francisco?

Airfare is above average for this route at the moment.

Santa Cruz de la Sierra to San Francisco flights typically cost between $834 and $837 in April.
The cheapest round-trip price found within the last 5 days was $983 on Copa Airlines (Apr 11-Apr 18).

Reviews of airlines servicing San Francisco

Read reviews from past customers who have flown Copa Airlines and United Airlines from Santa Cruz de la Sierra to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Food

7.0

Entertainment

6.9

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Food

7.0

Entertainment

6.9

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Boarding

7.8

Comfort

7.4

Overall

7.6

Crew

8.1

Food

7.0

Entertainment

6.9

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Related info for your journey

  • How long is the flight from Santa Cruz de la Sierra to San Francisco?

    Copa Airlines, United Airlines, and Avianca can get you from Santa Cruz de la Sierra to San Francisco in just under 17h 24m. Your travel time can differ by up to 18h 46m. Airlines will cover a distance of 5414 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to San Francisco round-trip?

    According to our current data, United Airlines ($299), and Copa Airlines ($466) offers the cheapest pricing from Santa Cruz de la Sierra to San Francisco. United Airlines is 75% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santa Cruz de la Sierra to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to San Francisco.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to San Francisco?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Hayward
Emeryville
Newark
Burlingame
San Bruno
Rancho Cordova
Vallejo
Cupertino
Fairfield
Redwood City
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Sunnyvale
Turlock
Davis
Morgan Hill
Roseville

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Alternative routes for Santa Cruz de la Sierra to San Francisco

Top 2 airlines flying from Santa Cruz de la Sierra to San Francisco

AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$299Average$837FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$466Average$1,180FlexibilityNo cancel feeOn-time70%

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