$364+ Cheap flights from Cusco (CUZ) to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
CUZ — SFO
May 28 — Jun 41
Round-trip
1 adult, Economy
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Find cheap flights from Cuzco to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Cuzco to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Cuzco to San FranciscoExplore the most affordable flight options available from Cuzco to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
Explore the most affordable flight options available from Cuzco to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
This LATAM Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:35 am
CUZ
- SFO
2 stops15h 48m
LATAM Airlines
Tue 5/267:15 am
SFO
- CUZ
2 stops22h 25m
LATAM Airlines
Deal found 4/27![LATAM Airlines logo]()
$744
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:25 am
CUZ
- SFO
2 stops17h 00m
Multiple Airlines
Wed 6/172:15 pm
SFO
- CUZ
2 stops19h 05m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$908
Best flights from Cuzco to San FranciscoDiscover carefully curated flight deals from Cuzco to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
Discover carefully curated flight deals from Cuzco to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
This LATAM Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:35 am
CUZ
- SFO
2 stops15h 48m
LATAM Airlines
Tue 5/267:15 am
SFO
- CUZ
2 stops22h 25m
LATAM Airlines
Deal found 4/27![LATAM Airlines logo]()
$744
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:25 am
CUZ
- SFO
2 stops17h 00m
Multiple Airlines
Wed 6/172:15 pm
SFO
- CUZ
2 stops19h 05m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$908
Last-minute flights from Cuzco to San FranciscoDiscover last-minute flight deals from Cuzco to San Francisco. Data last updated April 28, 2026 and is based on user searches.
Discover last-minute flight deals from Cuzco to San Francisco. Data last updated April 28, 2026 and is based on user searches.
This LATAM Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:35 am
CUZ
- SFO
2 stops15h 48m
LATAM Airlines
Tue 5/267:15 am
SFO
- CUZ
2 stops22h 25m
LATAM Airlines
Deal found 4/27![LATAM Airlines logo]()
$744
One-way flights from Cuzco to San FranciscoSearch for one-way flight options from Cuzco to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
Search for one-way flight options from Cuzco to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
This FlightHub deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:10 pm
CUZ
- SFO
2 stops21h 26m
LATAM Airlines
Deal found 4/27![LATAM Airlines logo]()
$364
This FlightHub deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:35 pm
CUZ
- SFO
2 stops26h 30m
LATAM Airlines
Deal found 4/27![LATAM Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:15 pm
CUZ
- SFO
2 stops20h 41m
Delta
Deal found 4/27![Delta logo]()
$379
This LATAM Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:10 pm
CUZ
- SFO
2 stops27h 35m
LATAM Airlines
Deal found 4/23![LATAM Airlines logo]()
$382
This LATAM Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:35 am
CUZ
- SFO
2 stops25h 46m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$383
This Travelocity deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:35 am
CUZ
- SFO
2 stops26h 02m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:30 pm
CUZ
- SFO
3 stops46h 54m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$421
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:55 am
CUZ
- SFO
3 stops29h 53m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$430
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/254:20 pm
CUZ
- SFO
3 stops45h 28m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$431
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:05 am
CUZ
- SFO
3 stops30h 43m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$432
This Ovago deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:55 pm
CUZ
- SFO
3 stops20h 29m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$440
Find flight deals from Cuzco to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Cuzco (CUZ) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.
Round-trip from | $744 (LATAM Airlines) |
|---|---|
One-way from | $364 (FlightHub) |
Cheapflights Fare Finder
Customize your flight search to find flights from Cuzco to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Cusco to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Fri 5/22
8:35 am-10:23 pm
2 stops15h 48m
San Francisco
Tue 5/26
7:15 am-7:40 am
2 stops22h 25m
$744
Quickest round-trip
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Wed 6/10
8:25 am-11:25 pm
2 stops17h 00m
San Francisco
Wed 6/17
2:15 pm-11:20 am
2 stops19h 05m
$908
Cheapest one-way
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Wed 5/27
6:10 pm-1:36 pm
2 stops21h 26m
$364
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Sat 8/8
6:45 pm-1:26 pm
2 stops20h 41m
$378
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Fri 5/8
9:15 pm-3:56 pm
2 stops20h 41m
$379
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Sat 5/9
7:30 am-8:21 am
2 stops26h 51m
$383
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Thu 5/7
10:35 pm-10:23 pm
2 stops25h 48m
$383
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Sun 9/6
8:35 am-8:37 am
2 stops26h 02m
$402
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Mon 9/7
10:30 pm-7:24 pm
3 stops46h 54m
$421
CuscoSan Francisco
CUZ - SFO
CUZSFO
Cusco Velazco Astete
Tue 5/26
7:55 am-11:48 am
3 stops29h 53m
$430
Showing 1-10 of 12 resultsSorted by cheapest first
Best time to book a flight from Cuzco to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Cuzco with our price prediction graph.
CUZ-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Cuzco to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
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San Bruno
Watsonville
San Ramon
Emeryville
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
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