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$320+ Cheap flights from San Francisco (SFO) to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — CUZ
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from San Francisco to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$699
(Priceline)

One-way from

$320
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$814
Provider with most accurate pricing for San Francisco-Cusco Velazco Astete flight deals.
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Provider most trusted by Cheapflights users for San Francisco-Cusco Velazco Astete flights.
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From San Francisco to Cusco Velazco Astete
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One-way flight from San Francisco to Cusco Velazco Astete
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Highest demand for flights based on searches. 7% potential increase in price ($71 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($46 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from San Francisco to Cuzco

Cheapest flights from San Francisco to Cuzco
Explore the most affordable flight options available from San Francisco to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This Priceline deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/261:20 pm
SFO
-
CUZ
2 stops19h 00m
Avianca
Tue 3/35:10 pm
CUZ
-
SFO
2 stops31h 40m
Avianca
Deal found 1/14$699
This Gotogate deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:15 pm
SFO
-
CUZ
2 stops18h 45m
Avianca
Sat 6/64:45 pm
CUZ
-
SFO
2 stops31h 50m
Avianca
Deal found 1/13$708
This Priceline deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:15 pm
SFO
-
CUZ
2 stops18h 45m
Avianca
Wed 4/2912:15 pm
CUZ
-
SFO
2 stops36h 20m
Avianca
Deal found 1/15$709
This FlightHub deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:03 pm
SFO
-
CUZ
2 stops16h 42m
LATAM Airlines
Wed 4/228:25 am
CUZ
-
SFO
2 stops16h 51m
LATAM Airlines
Deal found 1/14$720
This LATAM Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:05 am
SFO
-
CUZ
2 stops15h 40m
LATAM Airlines
Tue 3/108:10 pm
CUZ
-
SFO
2 stops17h 57m
LATAM Airlines
Deal found 1/13$752
This Mytrip deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:15 pm
SFO
-
CUZ
3 stops30h 10m
Multiple Airlines
Wed 4/2912:15 pm
CUZ
-
SFO
2 stops26h 35m
Multiple Airlines
Deal found 1/15$762
This Orbitz deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:20 pm
SFO
-
CUZ
2 stops43h 00m
Avianca
Wed 3/412:25 pm
CUZ
-
SFO
2 stops26h 35m
Avianca
Deal found 1/14$769
This Expedia deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/172:35 am
SFO
-
CUZ
2 stops30h 45m
Multiple Airlines
Thu 3/267:50 pm
CUZ
-
SFO
2 stops17h 40m
Multiple Airlines
Deal found 1/14$772
This FlightHub deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:00 am
SFO
-
CUZ
2 stops21h 35m
LATAM Airlines
Thu 6/1810:00 pm
CUZ
-
SFO
2 stops27h 12m
LATAM Airlines
Deal found 1/13$776
This Mytrip deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:20 pm
SFO
-
CUZ
2 stops19h 00m
Multiple Airlines
Mon 2/239:27 pm
CUZ
-
SFO
3 stops28h 53m
Multiple Airlines
Deal found 1/14$777
This Expedia deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1711:10 pm
SFO
-
CUZ
2 stops33h 10m
Multiple Airlines
Sun 2/226:50 am
CUZ
-
SFO
2 stops35h 13m
Multiple Airlines
Deal found 1/15$778
This Priceline deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/162:15 pm
SFO
-
CUZ
2 stops18h 45m
Avianca
Thu 7/24:45 pm
CUZ
-
SFO
2 stops31h 50m
Avianca
Deal found 1/14$782

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from San Francisco to Cusco that are best for you.

Fly from

San Francisco

Fly to

Cuzco

Route

Depart

Return

Price

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Thu 2/26

1:20 pm-11:20 am

2 stops19h 00m

Cusco Velazco Astete

Tue 3/3

5:10 pm-9:50 pm

2 stops31h 40m

$699

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Wed 4/22

2:15 pm-11:00 am

2 stops18h 45m

Cusco Velazco Astete

Wed 4/29

12:15 pm-10:35 pm

2 stops36h 20m

$709

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Sun 4/12

4:03 pm-11:35 am

2 stops17h 32m

Cusco Velazco Astete

Wed 4/22

8:25 am-11:16 pm

2 stops16h 51m

$720

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Mon 2/23

6:05 am-12:45 am

2 stops15h 40m

Cusco Velazco Astete

Tue 3/10

8:10 pm-12:07 pm

2 stops17h 57m

$752

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Wed 4/22

2:15 pm-10:25 pm

3 stops30h 10m

Cusco Velazco Astete

Wed 4/29

12:15 pm-12:50 pm

2 stops26h 35m

$762

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Fri 5/8

11:55 pm-8:40 pm

3 stops18h 45m

Cusco Velazco Astete

Fri 5/15

12:15 pm-12:50 pm

2 stops26h 35m

$769

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Fri 4/10

2:15 pm-11:00 am

2 stops18h 45m

Cusco Velazco Astete

Sat 4/18

9:20 pm-11:30 am

2 stops16h 10m

$772

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Fri 4/17

2:15 pm-11:00 am

2 stops18h 45m

Cusco Velazco Astete

Sat 4/25

4:45 pm-12:50 pm

2 stops22h 05m

$772

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Wed 6/10

7:00 am-6:35 am

2 stops21h 35m

Cusco Velazco Astete

Thu 6/18

10:00 pm-11:12 pm

2 stops27h 12m

$776

San FranciscoCusco

SFO - CUZ

SFOCUZ

San Francisco

Tue 2/17

11:10 pm-11:20 am

2 stops33h 10m

Cusco Velazco Astete

Sun 2/22

6:50 am-3:03 pm

2 stops35h 13m

$778

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/14

Showing 1-10 of 19 results
1
2

Compare providers for flights from San Francisco to Cuzco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Cuzco in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
Trip.comPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Cusco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Francisco-Cusco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Francisco-Cusco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Cusco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Cusco

How far ahead should I book a flight from San Francisco to Cusco?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Cuzco. Price data was last updated on January 9, 2026.

The best time to book flights from San Francisco to Cusco is 89 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from San Francisco to Cusco?

Currently, December is the cheapest month in which you can book a flight from San Francisco to Cusco (average of $343). Flying from San Francisco to Cusco in January is currently the most expensive (average of $774). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated January 15, 2026.
Read through reviews of airlines operating flights from San Francisco to Cusco, such as Delta, LATAM Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,051 reviews

Boarding

8.1

Food

7.2

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
8,051 reviews
Delta
7.9
Good
8,051 reviews

Boarding

8.1

Food

7.2

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,906 reviews
Delta
7.9
Good
8,051 reviews

Boarding

8.1

Food

7.2

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
11,136 reviews
Delta
7.9
Good
8,051 reviews

Boarding

8.1

Food

7.2

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.6
Okay
2,492 reviews
Delta
7.9
Good
8,051 reviews

Boarding

8.1

Food

7.2

Comfort

7.9

Overall

7.9

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Cusco?

    A quick flight from San Francisco to Cusco can take about 17h 32m. Avianca provides one of the quickest options available for as low as $720. San Francisco and Cusco are separated by a distance of 4810 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from San Francisco to Cusco round-trip?

    Cheapflights users have booked flights from San Francisco to Cusco round-trip from $548. Other airlines that can offer you cheap pricing are LATAM Airlines, from $743, and Delta, from $762. You may be able to fly from San Francisco to Cusco for 42% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from San Francisco to Cusco one-way?

    The cheapest airlines for a one-way flight from San Francisco to Cusco are Avianca ($276), Delta ($326), and LATAM Airlines ($430).

  • Where are the most common layover locations when flying from San Francisco to Cusco?

    Of the flights from San Francisco to Cusco that have layovers, most of them stop in Lima.

  • What are some popular things to do or see while on a layover in Lima?

    Plaza Mayor, Historic Centre of Lima, and Huaca Pucllana are currently the most popular points of interest in Lima at the moment. Plaza Mayor, Historic Centre of Lima and Huaca Pucllana are located about 5.9 mi, 5.9 mi, and 8.2 mi, respectively from Lima J Chavez Intl if you are interested in checking them out. Travelers can rent a car at Lima J Chavez Intl for an average daily rate of $40 to make sightseeing during their layover a little easier.

  • Where are the least popular layover locations for San Francisco to Cusco flights?

    Of the flights from San Francisco to Cusco that have layovers, the fewest flights stop in Los Angeles.

  • Can I find deals for flights from San Francisco to Cuzco that include hotel bookings?

    Yes. In addition to deals on San Francisco to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Cuzco.

  • Can I find deals for business class flights from San Francisco to Cuzco?

    Yes. Cheapflights offers flight deals from San Francisco to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Cusco?

    Currently, December is the cheapest month in which you can book a flight from San Francisco to Cusco (average of $343). Flying from San Francisco to Cusco in January is currently the most expensive (average of $774). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from San Francisco to Cuzco

Discover the top 4 airlines that operate flights from San Francisco to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$548Average$719FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$743Average$1,065FlexibilityNo cancel feeOn-time81%
DeltaCheapest$762Average$808FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$913Average$1,202FlexibilityNo cancel feeOn-time71%

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