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South America

$99+ Cheap flights from North Carolina to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — BOG
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
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Cheap flight deals from North Carolina to South America

Cheapest flights from North Carolina to South America
Explore the most affordable flight options available from North Carolina to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This CheapOair deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/259:34 pmCLT - GYE
2 stops26h 19mSpirit Airlines
jue. 2/51:26 amGYE - CLT
2 stops15h 28mSpirit Airlines
Deal found 12/10$380
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/296:00 amRDU - BOG
2 stops43h 12mMultiple Airlines
jue. 1/153:06 pmBOG - RDU
1 stop23h 07mMultiple Airlines
Deal found 12/11$380
This Cheapflightsfares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/148:55 pmCLT - MDE
1 stop17h 02mSpirit Airlines
dom. 12/212:25 amMDE - CLT
1 stop7h 14mSpirit Airlines
Deal found 12/10$398
This Cheapflightsfares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/229:34 pmCLT - MDE
1 stop13h 21mSpirit Airlines
jue. 1/293:15 pmMDE - CLT
1 stop16h 56mSpirit Airlines
Deal found 12/10$401
This KAYAK deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/285:50 pmRDU - BOG
1 stop7h 22mSpirit Airlines
jue. 1/153:06 pmBOG - RDU
1 stop23h 07mSpirit Airlines
Deal found 12/11$413
This Cheapflightsfares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/148:55 pmCLT - MDE
1 stop14h 00mSpirit Airlines
mar. 12/163:10 pmMDE - CLT
1 stop8h 49mSpirit Airlines
Deal found 12/10$431
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/286:00 amRDU - BOG
2 stops19h 12mMultiple Airlines
jue. 1/153:06 pmBOG - RDU
1 stop23h 07mMultiple Airlines
Deal found 12/11$432
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/118:14 pmRDU - MDE
1 stop19h 46mMultiple Airlines
dom. 12/142:05 amMDE - RDU
1 stop14h 50mMultiple Airlines
Deal found 12/10$437
This Cheapflightsfares deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/148:55 pmCLT - BOG
1 stop15h 57mSpirit Airlines
mié. 2/43:06 pmBOG - CLT
1 stop9h 34mSpirit Airlines
Deal found 12/11$444
This Priceline deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/259:34 pmCLT - GYE
2 stops26h 19mSpirit Airlines
mié. 12/3112:49 amGYE - CLT
2 stops19h 50mSpirit Airlines
Deal found 12/10$444
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/238:14 pmRDU - MDE
2 stops24h 01mMultiple Airlines
mié. 1/216:26 amMDE - RDU
1 stop6h 49mMultiple Airlines
Deal found 12/11$445
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/258:14 pmRDU - MDE
1 stop14h 41mMultiple Airlines
mié. 1/282:50 pmMDE - RDU
1 stop24h 50mMultiple Airlines
Deal found 12/11$446

Find flight deals from North Carolina to South America

Keep the following information in mind while searching for North Carolina to South America flight deals. Data was last updated diciembre 12, 2025.

Round-trip from

$253
(Copa Airlines)

One-way from

$99
(SmartFares)

Popular in

December

Cheapest in

November

Average price

$728
From North Carolina to South America
Search Deals
One-way flight from North Carolina to South America
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from North Carolina to South America that are best for you.

Fly from

North Carolina

Fly to

South America

Route

Depart

Return

Price

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

lun. 1/26

3:09 pm-10:40 pm

1 stop7h 31m

Medellín Jose Maria Cordova Intl

lun. 2/2

6:25 am-1:14 pm

1 stop6h 49m

$253

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

vie. 1/30

1:24 pm-12:21 am

1 stop10h 57m

Guayaquil Jose Joaquin de Olmedo

sáb. 2/7

1:26 am-9:39 pm

1 stop20h 13m

$276

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

mié. 1/14

6:00 am-12:21 am

1 stop18h 21m

Guayaquil Jose Joaquin de Olmedo

mar. 1/20

1:26 am-10:55 am

1 stop9h 29m

$276

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

dom. 1/11

3:09 pm-8:18 am

1 stop17h 09m

Medellín Jose Maria Cordova Intl

vie. 1/30

5:00 am-1:15 pm

1 stop8h 15m

$276

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

jue. 2/5

6:00 am-12:21 am

1 stop18h 21m

Guayaquil Jose Joaquin de Olmedo

mié. 2/18

12:59 am-6:02 pm

1 stop17h 03m

$277

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

vie. 1/9

7:43 pm-12:21 am

1 stop28h 38m

Guayaquil Jose Joaquin de Olmedo

jue. 1/29

1:26 am-8:58 pm

1 stop19h 32m

$279

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

lun. 2/9

1:24 pm-12:50 pm

2 stops23h 26m

Bogotá El Dorado

lun. 2/23

3:06 pm-8:26 am

1 stop17h 20m

$282

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

mié. 2/4

6:00 am-12:21 am

1 stop18h 21m

Guayaquil Jose Joaquin de Olmedo

mié. 2/18

12:59 am-6:02 pm

1 stop17h 03m

$284

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

vie. 1/23

3:09 pm-12:20 am

1 stop9h 11m

Bogotá El Dorado

vie. 1/30

6:10 am-1:15 pm

1 stop7h 05m

$291

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

mié. 1/21

7:43 pm-12:50 pm

2 stops17h 07m

Bogotá El Dorado

dom. 2/1

3:06 pm-8:11 am

1 stop17h 05m

$295

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 60 results
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Best time to book a flight from North Carolina to South America

Have a flexible travel schedule? Discover the best time to fly to South America from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to South America

What is the cheapest month to book a flight from North Carolina to South America?

Currently, October is the cheapest month in which you can book a flight from North Carolina to South America (average of $96). Flying from North Carolina to South America in July is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to SA?

Find hourly flight availability from North Carolina to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 12, 2025.

It’s optimal to fly from North Carolina to South America at noon. By choosing this option you can save up to 7% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from North Carolina to South America?

Use this chart to determine the cheapest time to fly round-trip from North Carolina to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their North Carolina to South America flight should consider departing on Tuesday at noon when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from North Carolina to South America?

    A quick flight from North Carolina to South America can take about 7h 31m. Copa Airlines provides one of the quickest options available for as low as $253. The distance from North Carolina to South America is about 2063 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from North Carolina to South America one-way?

    The cheapest airlines for a one-way flight from North Carolina to South America are Spirit Airlines ($96), Copa Airlines ($103), and American Airlines ($128).

  • Can I find deals for flights from North Carolina to South America that include hotel bookings?

    Yes. In addition to deals on North Carolina to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to South America.

  • Can I find deals for business class flights from North Carolina to South America?

    Yes. Cheapflights offers flight deals from North Carolina to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to South America?

    Currently, October is the cheapest month in which you can book a flight from North Carolina to South America (average of $96). Flying from North Carolina to South America in July is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for North Carolina to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from North Carolina to South America

Discover the top 8 airlines that operate flights from North Carolina to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$164Average$875FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$225Average$700FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$245Average$645FlexibilityNo cancel feeOn-time70%
Spirit AirlinesCheapest$247Average$492FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$283Average$878FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$297Average$456FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$314Average$691FlexibilityNo cancel feeOn-time69%
GOLCheapest$540Average$1,117FlexibilityNo cancel feeOn-time74%

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