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$92+ Cheap flights from North Carolina to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — BOG
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from North Carolina to South America

Keep the following information in mind while searching for North Carolina to South America flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$253
(Copa Airlines)

One-way from

$92
(CheapOair)

Popular in

January

Cheapest in

November

Average price

$614
Provider with most accurate pricing for Raleigh-Durham-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Sao Paulo (SAO) flights.
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From North Carolina to South America
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One-way flight from North Carolina to South America
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Highest demand for flights based on searches. 15% potential increase in price ($118 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from North Carolina to South America

Cheapest flights from North Carolina to South America
Explore the most affordable flight options available from North Carolina to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/263:14 pmRDU - MDE
1 stop17h 04mCopa Airlines
Wed 12/105:00 amMDE - RDU
1 stop8h 25mCopa Airlines
Deal found 10/30$253
This Orbitz deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:59 pmCLT - MDE
1 stop6h 57mSpirit Airlines
Wed 12/32:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 10/29$256
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:59 pmCLT - MDE
1 stop6h 57mSpirit Airlines
Wed 12/102:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 10/29$265
This Travelocity deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:55 pmCLT - BOG
1 stop15h 57mSpirit Airlines
Tue 12/93:05 pmBOG - CLT
1 stop8h 54mSpirit Airlines
Deal found 10/28$268
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:44 pmCLT - MDE
1 stop6h 13mSpirit Airlines
Fri 11/141:52 amMDE - CLT
1 stop7h 10mSpirit Airlines
Deal found 10/28$277
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:11 pmCLT - MDE
1 stop9h 45mSpirit Airlines
Fri 12/52:05 amMDE - CLT
1 stop7h 34mSpirit Airlines
Deal found 10/29$281
This Copa Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/103:14 pmRDU - MDE
1 stop17h 04mCopa Airlines
Mon 12/85:00 amMDE - RDU
1 stop8h 25mCopa Airlines
Deal found 10/29$285
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/53:11 pmRDU - MDE
1 stop17h 07mCopa Airlines
Wed 12/105:00 amMDE - RDU
1 stop8h 25mCopa Airlines
Deal found 10/28$287
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:07 amCLT - MDE
1 stop14h 50mSpirit Airlines
Tue 11/111:52 amMDE - CLT
1 stop7h 10mSpirit Airlines
Deal found 10/27$291
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:44 pmCLT - BOG
1 stop19h 26mSpirit Airlines
Fri 11/213:17 pmBOG - CLT
1 stop25h 33mSpirit Airlines
Deal found 10/29$295
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:11 pmCLT - MDE
1 stop9h 45mSpirit Airlines
Sat 12/133:10 pmMDE - CLT
1 stop8h 49mSpirit Airlines
Deal found 10/29$297
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:55 pmCLT - BOG
1 stop15h 57mSpirit Airlines
Wed 2/43:05 pmBOG - CLT
1 stop9h 54mSpirit Airlines
Deal found 10/29$298

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from North Carolina to South America that are best for you.

Fly from

North Carolina

Fly to

South America

Route

Depart

Return

Price

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Wed 11/26

3:14 pm-8:18 am

1 stop17h 04m

Medellín Jose Maria Cordova Intl

Wed 12/10

5:00 am-1:25 pm

1 stop8h 25m

$253

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Fri 2/6

9:46 pm-2:16 pm

2 stops16h 30m

Medellín Jose Maria Cordova Intl

Wed 2/11

3:11 pm-12:59 am

1 stop9h 48m

$280

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 11/10

3:14 pm-8:18 am

1 stop17h 04m

Medellín Jose Maria Cordova Intl

Mon 12/8

5:00 am-1:25 pm

1 stop8h 25m

$285

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Sun 1/11

3:09 pm-8:18 am

1 stop17h 09m

Medellín Jose Maria Cordova Intl

Fri 1/30

5:00 am-1:15 pm

1 stop8h 15m

$287

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Fri 12/5

3:11 pm-8:18 am

1 stop17h 07m

Medellín Jose Maria Cordova Intl

Wed 12/10

5:00 am-1:25 pm

1 stop8h 25m

$287

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 1/12

3:09 pm-8:18 am

1 stop17h 09m

Medellín Jose Maria Cordova Intl

Mon 1/19

5:00 am-1:15 pm

1 stop8h 15m

$298

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Thu 2/5

6:15 am-10:05 pm

1 stop15h 50m

Medellín Jose Maria Cordova Intl

Mon 2/9

10:45 am-10:30 pm

1 stop11h 45m

$303

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 11/10

8:00 pm-10:05 pm

2 stops26h 05m

Medellín Jose Maria Cordova Intl

Mon 12/8

10:45 am-2:07 pm

3 stops27h 22m

$308

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Tue 12/9

6:10 am-10:05 pm

2 stops15h 55m

Medellín Jose Maria Cordova Intl

Sun 12/14

1:15 am-6:47 pm

2 stops17h 32m

$308

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Thu 2/19

4:47 pm-5:10 am

1 stop12h 23m

Bogotá El Dorado

Sun 2/22

8:15 am-2:03 pm

3 stops29h 48m

$308

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 60 results
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Best time to book a flight from North Carolina to South America

Have a flexible travel schedule? Discover the best time to fly to South America from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to South America

What is the cheapest month to book a flight from North Carolina to South America?

Currently, October is the cheapest month in which you can book a flight from North Carolina to South America (average of $96). Flying from North Carolina to South America in July is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to SA?

Find hourly flight availability from North Carolina to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s optimal to fly from North Carolina to South America at noon. By choosing this option you can save up to 7% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from North Carolina to South America?

Use this chart to determine the cheapest time to fly round-trip from North Carolina to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their North Carolina to South America flight should consider departing on Tuesday at noon when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from North Carolina to South America?

    A quick flight from North Carolina to South America can take about 12h 23m. Copa Airlines provides one of the quickest options available for as low as $308. The distance from North Carolina to South America is about 2173 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from North Carolina to South America that include hotel bookings?

    Yes. In addition to deals on North Carolina to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to South America.

  • Can I find deals for business class flights from North Carolina to South America?

    Yes. Cheapflights offers flight deals from North Carolina to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to South America?

    Currently, October is the cheapest month in which you can book a flight from North Carolina to South America (average of $96). Flying from North Carolina to South America in July is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for North Carolina to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from North Carolina to South America

Discover the top 8 airlines that operate flights from North Carolina to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$164Average$869FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$225Average$695FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$245Average$614FlexibilityNo cancel feeOn-time70%
Spirit AirlinesCheapest$251Average$551FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$283Average$876FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$314Average$741FlexibilityNo cancel feeOn-time69%
JetBlueCheapest$374Average$475FlexibilityNo cancel feeOn-time62%
GOLCheapest$540Average$1,098FlexibilityNo cancel feeOn-time74%

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