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$95+ Cheap flights from North Carolina to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — BOG
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from North Carolina to South America

Cheapest flights from North Carolina to South America
Explore the most affordable flight options available from North Carolina to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Expedia deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
Wed 3/43:15 pm
MDE
-
CLT
1 stop8h 41m
Spirit Airlines
Deal found 1/28$234
This Orbitz deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
Thu 3/53:15 pm
MDE
-
CLT
1 stop8h 41m
Spirit Airlines
Deal found 1/28$237
This Orbitz deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/229:22 pm
CLT
-
MDE
1 stop17h 00m
Spirit Airlines
Wed 4/12:17 pm
MDE
-
CLT
1 stop9h 21m
Spirit Airlines
Deal found 1/28$242
This Travelocity deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
Wed 3/43:15 pm
MDE
-
CLT
1 stop8h 41m
Spirit Airlines
Deal found 1/28$243
This Copa Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/43:14 pm
RDU
-
MDE
1 stop17h 04m
Copa Airlines
Mon 3/96:25 am
MDE
-
RDU
1 stop6h 58m
Copa Airlines
Deal found 1/29$248
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:24 pm
CLT
-
MDE
1 stop11h 57m
Spirit Airlines
Sun 4/52:17 pm
MDE
-
CLT
1 stop9h 21m
Spirit Airlines
Deal found 1/28$251
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
CLT
-
MDE
1 stop8h 22m
Spirit Airlines
Tue 4/142:17 pm
MDE
-
CLT
1 stop9h 21m
Spirit Airlines
Deal found 1/27$253
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
Sat 3/73:15 pm
MDE
-
CLT
1 stop8h 41m
Spirit Airlines
Deal found 1/27$254
This Copa Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/23:12 pm
RDU
-
CTG
1 stop17h 29m
Copa Airlines
Wed 2/116:25 am
CTG
-
RDU
1 stop6h 49m
Copa Airlines
Deal found 1/27$259
This CheapOair deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/211:12 am
CLT
-
MDE
1 stop26h 43m
Spirit Airlines
Thu 3/53:15 pm
MDE
-
CLT
1 stop8h 41m
Spirit Airlines
Deal found 1/28$261
This Copa Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/183:12 pm
RDU
-
BOG
1 stop8h 53m
Copa Airlines
Wed 3/46:10 am
BOG
-
RDU
1 stop7h 13m
Copa Airlines
Deal found 1/27$263
This Cheapflightsfares deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
Tue 3/102:15 pm
MDE
-
CLT
1 stop17h 11m
Spirit Airlines
Deal found 1/28$264

Find flight deals from North Carolina to South America

Keep the following information in mind while searching for North Carolina to South America flight deals. Data was last updated January 29, 2026.

Round-trip from

$234
(Expedia)

One-way from

$95
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$392
From North Carolina to South America
Search Deals
One-way flight from North Carolina to South America
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($5 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from North Carolina to South America that are best for you.

Fly from

North Carolina

Fly to

South America

Route

Depart

Return

Price

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 3/14

9:22 pm-1:22 pm

1 stop17h 00m

Medellín Jose Maria Cordova Intl

Tue 3/17

2:17 pm-12:38 am

1 stop9h 21m

$242

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 3/2

5:55 am-2:13 pm

1 stop8h 18m

Medellín Jose Maria Cordova Intl

Thu 3/5

3:15 pm-8:26 am

1 stop17h 11m

$242

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Thu 4/2

1:24 pm-12:21 am

1 stop11h 57m

Medellín Jose Maria Cordova Intl

Thu 4/9

2:17 pm-12:38 am

1 stop9h 21m

$242

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sun 3/22

9:22 pm-1:22 pm

1 stop17h 00m

Medellín Jose Maria Cordova Intl

Wed 4/1

2:17 pm-12:38 am

1 stop9h 21m

$242

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Wed 3/4

3:14 pm-8:18 am

1 stop17h 04m

Medellín Jose Maria Cordova Intl

Mon 3/9

6:25 am-2:23 pm

1 stop6h 58m

$248

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 2/23

3:12 pm-8:18 am

1 stop17h 06m

Medellín Jose Maria Cordova Intl

Mon 3/9

5:00 am-2:23 pm

1 stop8h 23m

$248

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Tue 4/28

8:55 am-12:42 am

1 stop16h 47m

Medellín Jose Maria Cordova Intl

Tue 5/5

1:37 am-2:13 pm

1 stop11h 36m

$251

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Fri 3/6

5:55 am-2:13 pm

1 stop8h 18m

Medellín Jose Maria Cordova Intl

Wed 3/18

2:17 pm-8:21 am

1 stop17h 04m

$254

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Wed 2/25

3:12 pm-10:55 pm

1 stop7h 43m

Bogotá El Dorado

Tue 3/3

4:45 am-1:23 pm

1 stop8h 38m

$263

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Wed 2/18

3:12 pm-12:05 am

1 stop8h 53m

Bogotá El Dorado

Tue 3/3

4:45 am-1:23 pm

1 stop8h 38m

$263

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 60 results
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Best time to book a flight from North Carolina to South America

Have a flexible travel schedule? Discover the best time to fly to South America from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to South America

What is the cheapest month to book a flight from North Carolina to South America?

Currently, October is the cheapest month in which you can book a flight from North Carolina to South America (average of $96). Flying from North Carolina to South America in July is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from North Carolina to South America?

    A quick flight from North Carolina to South America can take about 9h 24m. Spirit Airlines provides one of the quickest options available for as low as $271. The distance from North Carolina to South America is about 1768 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from North Carolina to South America one-way?

    The cheapest airlines for a one-way flight from North Carolina to South America are Spirit Airlines ($101), Copa Airlines ($105), and American Airlines ($128).

  • Can I find deals for flights from North Carolina to South America that include hotel bookings?

    Yes. In addition to deals on North Carolina to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to South America.

  • Can I find deals for business class flights from North Carolina to South America?

    Yes. Cheapflights offers flight deals from North Carolina to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to South America?

    Currently, October is the cheapest month in which you can book a flight from North Carolina to South America (average of $96). Flying from North Carolina to South America in July is currently the most expensive (average of $285). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for North Carolina to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from North Carolina to South America

Discover the top 8 airlines that operate flights from North Carolina to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$149Average$427FlexibilityNo cancel feeOn-time65%
DeltaCheapest$161Average$856FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$225Average$697FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$245Average$637FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$264Average$608FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$282Average$910FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$297Average$431FlexibilityNo cancel feeOn-time62%
GOLCheapest$447Average$1,098FlexibilityNo cancel feeOn-time74%

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