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Knoxville

$759+ Cheap flights from Quito (UIO) to Knoxville (TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — TYS
Apr 10 — Apr 171
Fri 4/10
Fri 4/17
1 adult, Economy
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Cheap flight deals from Quito to Knoxville

Cheapest flights from Quito to Knoxville
Explore the most affordable flight options available from Quito to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.

This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:05 am
UIO
-
TYS
1 stop15h 54m
American Airlines
Tue 8/257:00 am
TYS
-
UIO
1 stop14h 58m
American Airlines
Deal found 3/9$759
This LATAM Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/212:59 am
UIO
-
TYS
1 stop9h 18m
LATAM Airlines
Mon 4/67:10 am
TYS
-
UIO
1 stop12h 49m
LATAM Airlines
Deal found 3/5$872
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:30 am
UIO
-
TYS
1 stop16h 29m
American Airlines
Thu 3/196:00 am
TYS
-
UIO
1 stop17h 04m
American Airlines
Deal found 3/5$1,136
This Priceline deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:30 am
UIO
-
TYS
3 stops22h 19m
Multiple Airlines
Thu 3/198:45 am
TYS
-
UIO
2 stops15h 15m
Multiple Airlines
Deal found 3/5$1,233
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/812:35 am
UIO
-
TYS
2 stops43h 12m
United Airlines
Mon 3/161:53 pm
TYS
-
UIO
2 stops34h 37m
United Airlines
Deal found 3/8$1,280

Find flight deals from Quito to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Quito (UIO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$759
(American Airlines)
Provider with most accurate pricing for Quito Mariscal Sucr-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Quito Mariscal Sucr-Knoxville McGhee Tyson flights.
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From Quito Mariscal Sucr to Knoxville McGhee Tyson
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Quito to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Quito to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Tue 5/12

7:05 am-10:12 pm

2 stops14h 07m

Knoxville McGhee Tyson

Tue 8/25

5:13 am-8:58 pm

2 stops16h 45m

$763

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Fri 4/3

6:30 pm-11:57 pm

2 stops28h 27m

Knoxville McGhee Tyson

Mon 4/6

7:10 am-6:59 pm

1 stop12h 49m

$872

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Quito-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Quito-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Quito-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Quito-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Quito-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Quito to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Quito with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Quito to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Quito to Knoxville?

    For as low as $763, American Airlines can have you in Knoxville from Quito in 14h 07m. There are 2507 mi between Quito and Knoxville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Quito to Knoxville that include hotel bookings?

    Yes. In addition to deals on Quito to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Quito to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Quito to Knoxville.

  • Can I find deals for business class flights from Quito to Knoxville?

    Yes. Cheapflights offers flight deals from Quito to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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