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$91+ Cheap flights from Indiana to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
IND — BOG
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Indiana to South America

Keep the following information in mind while searching for Indiana to South America flight deals. Data was last updated September 11, 2025.

Round-trip from

$287
(CheapOair)

One-way from

$91
(Cheapflightsfares)

Popular in

April

Cheapest in

May
From Indiana to South America
Search Deals
One-way flight from Indiana to South America
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($554 potential increase over avg. RT price).
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Cheapest flight prices on average. 25% potential price decrease ($266 potential savings vs. average RT price).
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Find flight deals from Indiana to South America

Cheapest flights from Indiana to South America
Explore the most affordable flight options available from Indiana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:05 amORD - CTG
1 stop7h 03mSpirit Airlines
Tue 11/182:16 pmCTG - ORD
1 stop10h 26mSpirit Airlines
Deal found 9/9$287
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/55:05 amORD - CTG
1 stop7h 20mSpirit Airlines
Sat 10/111:32 pmCTG - ORD
1 stop10h 13mSpirit Airlines
Deal found 9/10$289
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/243:07 pmORD - CTG
1 stop17h 35mCopa Airlines
Mon 10/276:21 amCTG - ORD
1 stop18h 35mCopa Airlines
Deal found 9/10$290
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:57 amORD - MDE
1 stop12h 31mSpirit Airlines
Wed 10/152:22 pmMDE - ORD
1 stop9h 23mSpirit Airlines
Deal found 9/9$293
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/411:57 amORD - MDE
1 stop12h 31mSpirit Airlines
Sat 10/182:22 pmMDE - ORD
1 stop9h 23mSpirit Airlines
Deal found 9/9$294
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:00 pmORD - CTG
2 stops18h 25mSpirit Airlines
Fri 10/241:32 pmCTG - ORD
1 stop10h 13mSpirit Airlines
Deal found 9/10$295
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:57 amORD - MDE
1 stop12h 31mSpirit Airlines
Thu 10/162:22 pmMDE - ORD
1 stop9h 23mSpirit Airlines
Deal found 9/9$295
This Avianca deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:20 pmORD - CTG
1 stop13h 10mAvianca
Mon 11/108:25 amCTG - ORD
1 stop12h 55mAvianca
Deal found 9/11$296
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:05 amORD - CTG
1 stop7h 18mSpirit Airlines
Fri 9/261:29 pmCTG - ORD
1 stop9h 19mSpirit Airlines
Deal found 9/9$297
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/137:43 pmORD - MDE
1 stop28h 38mSpirit Airlines
Fri 10/172:22 pmMDE - ORD
1 stop9h 23mSpirit Airlines
Deal found 9/10$297
This KAYAK deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:59 pmORD - CTG
1 stop18h 09mSpirit Airlines
Tue 11/112:16 pmCTG - ORD
1 stop7h 44mSpirit Airlines
Deal found 9/9$298
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/511:55 amORD - MDE
1 stop12h 26mSpirit Airlines
Sun 10/121:16 amMDE - ORD
1 stop9h 34mSpirit Airlines
Deal found 9/11$298

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Indiana to South America that are best for you.

Fly from

Indiana

Fly to

South America

Route

Depart

Return

Price

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Fri 10/24

3:07 pm-8:42 am

1 stop17h 35m

Cartagena Rafael Nunez

Mon 10/27

6:21 am-12:56 am

1 stop18h 35m

$290

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Mon 9/22

8:02 am-11:24 pm

1 stop15h 22m

Cartagena Rafael Nunez

Wed 10/1

9:42 am-12:21 am

1 stop14h 39m

$290

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Wed 10/22

3:07 pm-8:42 am

1 stop17h 35m

Cartagena Rafael Nunez

Tue 10/28

3:10 pm-12:56 am

1 stop9h 46m

$290

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Fri 11/7

2:07 pm-8:41 am

1 stop17h 34m

Cartagena Rafael Nunez

Mon 11/10

6:24 am-12:05 am

1 stop18h 41m

$290

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Sun 9/14

8:02 am-12:06 am

1 stop16h 04m

Bogotá El Dorado

Tue 9/16

11:39 am-12:21 am

1 stop12h 42m

$309

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Fri 10/31

3:07 pm-12:05 am

1 stop8h 58m

Bogotá El Dorado

Sun 11/2

4:45 am-12:46 pm

1 stop9h 01m

$321

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Thu 11/13

2:07 pm-12:05 am

1 stop8h 58m

Bogotá El Dorado

Sun 11/16

4:45 am-12:46 pm

1 stop9h 01m

$321

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Wed 11/5

6:56 am-10:55 pm

1 stop14h 59m

Bogotá El Dorado

Tue 11/11

4:45 am-12:46 pm

1 stop9h 01m

$321

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Wed 12/10

2:07 pm-8:06 am

1 stop16h 59m

Cartagena Rafael Nunez

Wed 12/17

6:25 am-12:05 am

1 stop18h 40m

$325

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Sun 10/5

8:49 pm-1:04 pm

1 stop16h 15m

Medellín Jose Maria Cordova Intl

Tue 10/14

1:16 am-6:38 pm

1 stop17h 22m

$332

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/8

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to South America

What is the cheapest month to book a flight from Indiana to South America?

Currently, May is the cheapest month in which you can book a flight from Indiana to South America (average of $359). Flying from Indiana to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SA?

Find hourly flight availability from Indiana to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Indiana to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Indiana to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indiana to South America?

    For as low as $340, Copa Airlines can have you in South America from Indiana in 8h 11m. The distance between Indiana and South America is about 2589 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Indiana to South America one-way?

    $91 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Copa Airlines and LATAM Airlines, with prices starting from $123 and $194, respectively.

  • Can I find deals for flights from Indiana to South America that include hotel bookings?

    Yes. In addition to deals on Indiana to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to South America.

  • Can I find deals for business class flights from Indiana to South America?

    Yes. Cheapflights offers flight deals from Indiana to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to South America?

    Currently, May is the cheapest month in which you can book a flight from Indiana to South America (average of $359). Flying from Indiana to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Indiana to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Indiana to South America

Discover the top 5 airlines that operate flights from Indiana to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$288Average$617FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$426Average$1,140FlexibilityNo cancel feeOn-time81%
DeltaCheapest$426Average$946FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$495Average$955FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$538Average$1,077FlexibilityNo cancel feeOn-time69%

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