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South America

$96+ Cheap flights from Indiana to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel.
IND — BOG
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Indiana to South America

Cheapest flights from Indiana to South America
Explore the most affordable flight options available from Indiana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:35 amORD - MDE
1 stop13h 30mUnited Airlines
Sun 12/141:15 amMDE - ORD
1 stop10h 56mUnited Airlines
Deal found 12/11$303
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1110:35 amORD - MDE
1 stop10h 30mUnited Airlines
Sun 12/1410:45 amMDE - ORD
1 stop23h 27mUnited Airlines
Deal found 12/11$310
This Copa Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:07 pmORD - MDE
1 stop17h 11mCopa Airlines
Tue 12/166:24 amMDE - ORD
1 stop18h 41mCopa Airlines
Deal found 12/11$346
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:07 pmORD - CTG
1 stop19h 23mAmerican Airlines
Wed 12/174:30 pmCTG - ORD
1 stop17h 17mAmerican Airlines
Deal found 12/10$369
This Copa Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:07 pmORD - MDE
1 stop17h 11mCopa Airlines
Tue 12/165:00 amMDE - ORD
1 stop8h 52mCopa Airlines
Deal found 12/11$374
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:35 amORD - MDE
1 stop13h 30mUnited Airlines
Tue 12/161:15 amMDE - ORD
1 stop10h 57mUnited Airlines
Deal found 12/11$388
This Copa Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:07 pmORD - CTG
1 stop16h 59mCopa Airlines
Sun 12/149:42 amCTG - ORD
1 stop15h 23mCopa Airlines
Deal found 12/8$404
This Copa Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/217:33 amORD - MDE
1 stop11h 27mCopa Airlines
Sat 12/2710:46 amMDE - ORD
1 stop12h 35mCopa Airlines
Deal found 12/11$404
This Copa Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:33 amORD - MDE
1 stop14h 15mCopa Airlines
Sun 12/1412:42 pmMDE - ORD
1 stop12h 23mCopa Airlines
Deal found 12/9$405
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:07 pmORD - CTG
1 stop19h 54mMultiple Airlines
Fri 12/128:25 amCTG - ORD
1 stop12h 55mMultiple Airlines
Deal found 12/8$408
This Copa Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:33 amORD - CTG
1 stop14h 27mCopa Airlines
Fri 12/193:04 pmCTG - ORD
1 stop10h 01mCopa Airlines
Deal found 12/11$419
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:00 amORD - CTG
2 stops9h 30mAmerican Airlines
Fri 12/128:00 amCTG - ORD
2 stops12h 44mAmerican Airlines
Deal found 12/8$421

Find flight deals from Indiana to South America

Keep the following information in mind while searching for Indiana to South America flight deals. Data was last updated December 12, 2025.

Round-trip from

$295
(FlightHub)

One-way from

$96
(Kiwi.com)

Popular in

March

Cheapest in

January

Average price

$434
From Indiana to South America
Search Deals
One-way flight from Indiana to South America
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($139 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Indiana to South America that are best for you.

Fly from

Indiana

Fly to

South America

Route

Depart

Return

Price

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Sun 3/1

7:35 am-10:05 pm

1 stop13h 30m

Medellín Jose Maria Cordova Intl

Mon 3/9

9:45 am-12:26 am

1 stop14h 41m

$303

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Sun 3/1

7:35 am-10:05 pm

1 stop13h 30m

Medellín Jose Maria Cordova Intl

Sat 3/7

10:45 am-12:26 am

1 stop14h 41m

$303

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Sun 3/1

5:45 am-10:05 pm

1 stop15h 20m

Medellín Jose Maria Cordova Intl

Fri 3/6

10:45 am-12:26 am

1 stop14h 41m

$303

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Wed 2/25

7:35 am-10:05 pm

1 stop13h 30m

Medellín Jose Maria Cordova Intl

Sat 3/7

10:45 am-12:26 am

1 stop14h 41m

$303

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Wed 2/25

8:53 am-10:05 pm

1 stop12h 12m

Medellín Jose Maria Cordova Intl

Fri 3/6

10:45 am-12:26 am

1 stop14h 41m

$303

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Mon 2/2

8:55 pm-1:30 pm

2 stops15h 35m

Cartagena Rafael Nunez

Fri 2/6

2:30 pm-7:22 am

2 stops17h 52m

$307

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Thu 3/5

2:22 pm-9:25 am

1 stop18h 03m

Bogotá El Dorado

Tue 3/10

4:45 am-1:31 pm

1 stop8h 46m

$309

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Sat 1/17

2:13 pm-10:10 am

1 stop18h 57m

Bogotá El Dorado

Wed 1/28

7:00 am-12:24 am

1 stop18h 24m

$309

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Wed 1/28

2:13 pm-12:05 am

1 stop8h 52m

Bogotá El Dorado

Fri 2/6

4:45 am-12:31 pm

1 stop8h 46m

$309

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Thu 2/5

8:43 pm-1:15 pm

1 stop15h 32m

Cartagena Rafael Nunez

Mon 2/9

2:21 pm-11:46 pm

1 stop10h 25m

$310

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to South America

What is the cheapest month to book a flight from Indiana to South America?

Currently, December is the cheapest month in which you can book a flight from Indiana to South America (average of $247). Flying from Indiana to South America in April is currently the most expensive (average of $534). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SA?

Find hourly flight availability from Indiana to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 23% on flights from Indiana to South America by exploring options for tickets in the evening.

What is the cheapest day to fly from Indiana to South America?

Use this chart to determine the cheapest time to fly round-trip from Indiana to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Indiana to South America flight should consider departing on Saturday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Indiana to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indiana to South America?

    For as low as $303, United Airlines can have you in South America from Indiana in 13h 30m. The distance between Indiana and South America is about 2589 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Indiana to South America one-way?

    $95 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on American Airlines and LATAM Airlines, with prices starting from $302 and $312, respectively.

  • Can I find deals for flights from Indiana to South America that include hotel bookings?

    Yes. In addition to deals on Indiana to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to South America.

  • Can I find deals for business class flights from Indiana to South America?

    Yes. Cheapflights offers flight deals from Indiana to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to South America?

    Currently, December is the cheapest month in which you can book a flight from Indiana to South America (average of $247). Flying from Indiana to South America in April is currently the most expensive (average of $534). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Indiana to South America

Discover the top 6 airlines that operate flights from Indiana to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$263Average$629FlexibilityNo cancel feeOn-time65%
Copa AirlinesCheapest$420Average$659FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$426Average$833FlexibilityNo cancel feeOn-time81%
DeltaCheapest$523Average$918FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$528Average$886FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$538Average$1,105FlexibilityNo cancel feeOn-time69%

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