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$104+ Cheap flights from Indiana to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
IND — BOG
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Cheap flight deals from Indiana to South America

Keep the following information in mind while searching for Indiana to South America flight deals. Data was last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$251
(Orbitz)

One-way from

$104
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$1,078
Provider with most accurate pricing for Indianapolis-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Sao Paulo (SAO) flights.
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From Indiana to South America
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One-way flight from Indiana to South America
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Highest demand for flights based on searches. 11% potential increase in price ($130 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($38 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Indiana to South America

Cheapest flights from Indiana to South America
Explore the most affordable flight options available from Indiana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:10 amORD - CTG
1 stop7h 05mSpirit Airlines
Fri 11/142:20 pmCTG - ORD
1 stop11h 07mSpirit Airlines
Deal found 10/28$272
This CheapOair deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/165:10 amORD - CTG
1 stop7h 05mSpirit Airlines
Wed 11/192:20 pmCTG - ORD
1 stop11h 07mSpirit Airlines
Deal found 10/28$283
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:10 amORD - CTG
1 stop7h 05mSpirit Airlines
Sat 11/152:20 pmCTG - ORD
1 stop11h 07mSpirit Airlines
Deal found 10/27$287
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:00 amORD - BOG
1 stop8h 10mSpirit Airlines
Fri 12/122:17 amBOG - ORD
1 stop18h 44mSpirit Airlines
Deal found 10/27$289
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/152:07 pmORD - CTG
1 stop16h 59mCopa Airlines
Wed 11/269:42 amCTG - ORD
1 stop15h 23mCopa Airlines
Deal found 10/28$290
This CheapOair deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/235:00 amORD - CTG
1 stop7h 25mSpirit Airlines
Thu 11/272:30 pmCTG - ORD
1 stop9h 43mSpirit Airlines
Deal found 10/28$291
This FlightHub deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2811:20 pmORD - CTG
1 stop13h 10mAvianca
Tue 11/411:05 amCTG - ORD
1 stop10h 15mAvianca
Deal found 10/27$293
This KAYAK deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/63:26 pmORD - CTG
1 stop20h 44mSpirit Airlines
Wed 12/102:15 pmCTG - ORD
1 stop10h 54mSpirit Airlines
Deal found 10/26$295
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/125:10 amORD - CTG
1 stop7h 05mSpirit Airlines
Wed 11/192:20 pmCTG - ORD
1 stop11h 07mSpirit Airlines
Deal found 10/27$299
This CheapOair deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:00 amORD - CTG
1 stop7h 25mSpirit Airlines
Mon 12/82:15 pmCTG - ORD
1 stop10h 54mSpirit Airlines
Deal found 10/26$301
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/157:07 pmORD - CTG
1 stop17h 19mAmerican Airlines
Wed 11/194:30 pmCTG - ORD
1 stop9h 07mAmerican Airlines
Deal found 10/26$302
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:10 amORD - CTG
1 stop7h 05mSpirit Airlines
Wed 11/192:20 pmCTG - ORD
1 stop11h 07mSpirit Airlines
Deal found 10/27$303

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Indiana to South America that are best for you.

Fly from

Indiana

Fly to

South America

Route

Depart

Return

Price

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Wed 11/26

2:07 pm-8:06 am

1 stop16h 59m

Cartagena Rafael Nunez

Wed 12/3

3:04 pm-12:05 am

1 stop10h 01m

$290

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Sat 11/15

2:07 pm-8:06 am

1 stop16h 59m

Cartagena Rafael Nunez

Wed 11/26

9:42 am-12:05 am

1 stop15h 23m

$290

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Thu 11/13

2:07 pm-8:41 am

1 stop17h 34m

Cartagena Rafael Nunez

Wed 11/19

6:24 am-12:05 am

1 stop18h 41m

$290

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Mon 12/1

2:07 pm-10:10 am

1 stop19h 03m

Bogotá El Dorado

Sat 12/6

3:40 am-12:52 pm

1 stop10h 12m

$309

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Sun 11/9

2:07 pm-12:20 am

1 stop9h 13m

Bogotá El Dorado

Tue 11/11

4:45 am-12:46 pm

1 stop9h 01m

$309

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Fri 11/14

2:07 pm-12:05 am

1 stop8h 58m

Bogotá El Dorado

Fri 12/12

4:40 pm-12:05 am

1 stop8h 25m

$309

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Thu 11/13

2:07 pm-12:20 am

1 stop9h 13m

Bogotá El Dorado

Thu 11/20

8:40 am-12:05 am

1 stop16h 25m

$309

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Sun 11/16

6:56 am-5:26 pm

1 stop9h 30m

Bogotá El Dorado

Wed 11/19

4:45 am-12:46 pm

1 stop9h 01m

$309

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Sun 11/16

6:56 am-10:55 pm

1 stop14h 59m

Bogotá El Dorado

Sat 11/22

4:45 am-12:46 pm

1 stop9h 01m

$309

ChicagoBogotá

ORD - BOG

ORDBOG

Chicago O'Hare Intl

Fri 11/21

6:56 am-12:20 am

1 stop16h 24m

Bogotá El Dorado

Wed 11/26

6:08 pm-12:46 pm

1 stop19h 38m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to South America

What is the cheapest month to book a flight from Indiana to South America?

Currently, February is the cheapest month in which you can book a flight from Indiana to South America (average of $260). Flying from Indiana to South America in March is currently the most expensive (average of $470). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SA?

Find hourly flight availability from Indiana to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 24% on flights from Indiana to South America by exploring options for tickets in the evening.

What is the cheapest day to fly from Indiana to South America?

Use this chart to determine the cheapest time to fly round-trip from Indiana to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Indiana to South America flight should consider departing on Saturday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Indiana to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indiana to South America?

    For as low as $358, Copa Airlines can have you in South America from Indiana in 8h 11m. The distance between Indiana and South America is about 2589 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Indiana to South America one-way?

    $104 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Copa Airlines and United Airlines, with prices starting from $123 and $156, respectively.

  • Can I find deals for flights from Indiana to South America that include hotel bookings?

    Yes. In addition to deals on Indiana to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to South America.

  • Can I find deals for business class flights from Indiana to South America?

    Yes. Cheapflights offers flight deals from Indiana to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to South America?

    Currently, February is the cheapest month in which you can book a flight from Indiana to South America (average of $260). Flying from Indiana to South America in March is currently the most expensive (average of $470). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Indiana to South America

Discover the top 6 airlines that operate flights from Indiana to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$278Average$624FlexibilityNo cancel feeOn-time65%
Copa AirlinesCheapest$420Average$659FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$426Average$1,123FlexibilityNo cancel feeOn-time81%
DeltaCheapest$523Average$912FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$528Average$1,008FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$538Average$1,025FlexibilityNo cancel feeOn-time69%

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