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$823+ Cheap flights from Louisville (SDF) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/8. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — SCL
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Louisville to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$823
(Mytrip)

Popular in

December

Cheapest in

April

Average price

$1,055
From Louisville Intl to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 10% potential increase in price ($127 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($33 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Louisville to Santiago

Cheapest flights from Louisville to Santiago
Explore the most affordable flight options available from Louisville to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/87:45 amSDF - SCL
2 stops20h 30mMultiple Airlines
Fri 9/123:33 pmSCL - SDF
3 stops28h 59mMultiple Airlines
Deal found 7/2$823
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/292:34 pmSDF - SCL
1 stop13h 36mDelta
Wed 1/1410:35 amSCL - SDF
2 stops15h 21mDelta
Deal found 7/3$828
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:00 amSDF - SCL
1 stop24h 50mAmerican Airlines
Wed 1/1410:15 pmSCL - SDF
1 stop28h 02mAmerican Airlines
Deal found 7/2$925
This LATAM Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/294:36 pmSDF - SCL
3 stops19h 54mLATAM Airlines
Wed 1/146:30 pmSCL - SDF
2 stops19h 07mLATAM Airlines
Deal found 7/2$928
This Copa Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1810:00 amSDF - SCL
2 stops19h 02mCopa Airlines
Tue 8/1912:13 amSCL - SDF
2 stops20h 49mCopa Airlines
Deal found 6/30$1,206

Cheapflights Fare Finder

Customize your flight search to find flights from Louisville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Louisville to Santiago that are best for you.

Fly from

Louisville

Fly to

Santiago

Route

Depart

Return

Price

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Mon 9/8

7:45 am-5:15 am

2 stops20h 30m

Santiago Arturo Merino Benitez

Fri 9/12

3:33 pm-7:32 pm

3 stops28h 59m

$823

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Mon 12/29

12:37 pm-7:00 am

2 stops16h 23m

Santiago Arturo Merino Benitez

Wed 1/14

10:35 am-11:56 pm

2 stops15h 21m

$828

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Mon 12/29

5:00 am-7:50 am

1 stop24h 50m

Santiago Arturo Merino Benitez

Wed 1/14

10:15 pm-12:17 am

1 stop28h 02m

$925

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Mon 12/29

4:36 pm-2:30 pm

3 stops19h 54m

Santiago Arturo Merino Benitez

Wed 1/14

6:30 pm-11:37 am

2 stops19h 07m

$928

LouisvilleSantiago

SDF - SCL

SDFSCL

Louisville Intl

Mon 8/18

10:00 am-5:02 am

2 stops19h 02m

Santiago Arturo Merino Benitez

Tue 8/19

12:13 am-9:02 pm

2 stops20h 49m

$1,206

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Louisville to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Santiago

What is the cheapest month to book a flight from Louisville to Santiago?

Currently, April is the cheapest month in which you can book a flight from Louisville to Santiago (average of $752). Flying from Louisville to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to SCL?

Find hourly flight availability from Louisville to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

It’s typically best to fly out from Louisville to Santiago at noon. Doing so could potentially save you 20% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 3, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and Copa Airlines from Louisville to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,805 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,467 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Louisville to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Louisville to Santiago round-trip?

    Cheapflights users have booked flights from Louisville to Santiago round-trip from $828. Other airlines that can offer you cheap pricing are American Airlines, from $925, and LATAM Airlines, from $928. Users have found that Delta is 19% cheaper than the other options available to this destination.

  • Can I find deals for flights from Louisville to Santiago that include hotel bookings?

    Yes. In addition to deals on Louisville to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Santiago.

  • Can I find deals for business class flights from Louisville to Santiago?

    Yes. Cheapflights offers flight deals from Louisville to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Louisville to Santiago (average of $752). Flying from Louisville to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Louisville to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Louisville to Santiago

Discover the top airline that operate flights from Louisville to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$752Average$1,074FlexibilityNo cancel feeOn-time81%

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