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$658+ Cheap flights from Lexington (LEX) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — SCL
Aug 21 — Aug 281
Fri 8/21
Fri 8/28
1 adult, Economy
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Cheap flight deals from Lexington to Santiago

Cheapest flights from Lexington to Santiago
Explore the most affordable flight options available from Lexington to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.

This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:05 am
LEX
-
SCL
2 stops19h 45m
United Airlines
Thu 12/310:45 pm
SCL
-
LEX
2 stops21h 52m
United Airlines
Deal found 7/22$1,000
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/261:18 pm
LEX
-
SCL
2 stops17h 42m
American Airlines
Thu 12/311:45 pm
SCL
-
LEX
2 stops20h 39m
American Airlines
Deal found 7/19$1,002
This oojo deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:05 am
LEX
-
SCL
2 stops18h 50m
LATAM Airlines
Thu 12/38:30 am
SCL
-
LEX
3 stops30h 07m
LATAM Airlines
Deal found 7/19$1,036
This oojo deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:05 am
LEX
-
SCL
2 stops18h 50m
LATAM Airlines
Wed 12/28:30 am
SCL
-
LEX
3 stops30h 07m
LATAM Airlines
Deal found 7/19$1,057
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:00 am
LEX
-
SCL
2 stops21h 50m
United Airlines
Sun 11/110:45 pm
SCL
-
LEX
2 stops26h 57m
United Airlines
Deal found 7/21$1,072
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:05 am
LEX
-
SCL
1 stop19h 35m
Delta
Wed 12/211:10 pm
SCL
-
LEX
1 stop21h 44m
Delta
Deal found 7/20$1,077
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:55 pm
LEX
-
SCL
1 stop11h 45m
Delta
Thu 12/311:10 pm
SCL
-
LEX
1 stop17h 50m
Delta
Deal found 7/22$1,085
This LATAM Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:04 pm
LEX
-
SCL
2 stops16h 51m
LATAM Airlines
Sun 11/111:10 pm
SCL
-
LEX
1 stop14h 59m
LATAM Airlines
Deal found 7/18$1,107

Find flight deals from Lexington to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 22, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$1,000
(United Airlines)

One-way from

$658
(American Airlines)
Provider with most accurate pricing for Lexington Blue Grass-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lexington Blue Grass-Santiago Arturo Merino Benitez flights.
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From Lexington Blue Grass to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Lexington Blue Grass to Santiago Arturo Merino Benitez
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
Use the filters below to find and compare flights from Lexington to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Thu 11/26

11:05 am-8:50 am

2 stops19h 45m

Santiago Arturo Merino Benitez

Thu 12/3

10:45 pm-6:37 pm

2 stops21h 52m

$1,000

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Thu 11/26

7:00 am-9:00 am

2 stops24h 00m

Santiago Arturo Merino Benitez

Wed 12/2

10:15 pm-1:25 pm

2 stops17h 10m

$1,002
Quickest round-trip

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Thu 11/26

11:26 am-9:00 am

2 stops19h 34m

Santiago Arturo Merino Benitez

Thu 12/3

11:45 pm-1:25 pm

1 stop15h 40m

$1,002
Cheapest one-way
Quickest one-way

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Mon 9/14

7:36 am-8:00 am

2 stops23h 24m

$658

LexingtonSantiago

LEX - SCL

LEXSCL

Lexington Blue Grass

Mon 9/14

10:08 am-2:25 pm

3 stops27h 17m

$698

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/18

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Lexington-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Lexington-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Lexington-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lexington-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lexington-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lexington to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Lexington to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lexington to Santiago?

    Departing from Lexington to Santiago will take you 19h 45m. Lexington and Santiago are separated by a distance of 5011 mi.

  • Can I find deals for flights from Lexington to Santiago that include hotel bookings?

    Yes. In addition to deals on Lexington to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Santiago.

  • Can I find deals for business class flights from Lexington to Santiago?

    Yes. Cheapflights offers flight deals from Lexington to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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