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Guayaquil

$350+ Cheap flights from Louisville (SDF) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — GYE
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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Cheap flight deals from Louisville to Guayaquil

Cheapest flights from Louisville to Guayaquil
Explore the most affordable flight options available from Louisville to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:19 pm
SDF
-
GYE
2 stops18h 06m
American Airlines
Tue 8/42:25 pm
GYE
-
SDF
2 stops22h 39m
American Airlines
Deal found 4/26$726
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:25 pm
SDF
-
GYE
2 stops20h 00m
American Airlines
Wed 8/56:00 am
GYE
-
SDF
2 stops16h 00m
American Airlines
Deal found 4/27$754
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:10 am
SDF
-
GYE
2 stops17h 28m
United Airlines
Sat 8/298:28 am
GYE
-
SDF
2 stops27h 27m
United Airlines
Deal found 4/26$770
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:24 pm
SDF
-
GYE
2 stops19h 03m
American Airlines
Sun 12/276:04 am
GYE
-
SDF
1 stop17h 55m
American Airlines
Deal found 4/27$778
This Gurufare deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:50 am
SDF
-
GYE
2 stops19h 11m
Copa Airlines
Sat 5/232:43 pm
GYE
-
SDF
2 stops18h 40m
Copa Airlines
Deal found 4/27$798
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:12 pm
SDF
-
GYE
2 stops28h 33m
American Airlines
Sat 8/296:00 am
GYE
-
SDF
1 stop16h 44m
American Airlines
Deal found 4/26$822
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:15 am
SDF
-
GYE
2 stops18h 23m
United Airlines
Tue 9/82:37 pm
GYE
-
SDF
2 stops17h 38m
United Airlines
Deal found 4/27$936

Find flight deals from Louisville to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$726
(American Airlines)

One-way from

$350
(Gurufare)
Provider with most accurate pricing for Louisville Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
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Provider most trusted by Cheapflights users for Louisville Intl-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Louisville Intl to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Louisville Intl to Guayaquil Jose Joaquin de Olmedo
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Louisville to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

LouisvilleGuayaquil

SDF - GYE

SDFGYE

Louisville Intl

Fri 7/24

8:19 pm-1:25 pm

2 stops18h 06m

Guayaquil Jose Joaquin de Olmedo

Wed 8/5

6:00 am-10:37 pm

1 stop15h 37m

$754

LouisvilleGuayaquil

SDF - GYE

SDFGYE

Louisville Intl

Fri 8/21

7:10 am-11:38 pm

2 stops17h 28m

Guayaquil Jose Joaquin de Olmedo

Sat 8/29

8:28 am-12:55 pm

2 stops27h 27m

$770

LouisvilleGuayaquil

SDF - GYE

SDFGYE

Louisville Intl

Fri 7/24

5:39 pm-1:34 pm

2 stops20h 55m

Guayaquil Jose Joaquin de Olmedo

Tue 8/4

2:37 pm-2:04 pm

2 stops22h 27m

$783

LouisvilleGuayaquil

SDF - GYE

SDFGYE

Louisville Intl

Sat 5/16

5:50 am-12:01 am

2 stops19h 11m

Guayaquil Jose Joaquin de Olmedo

Sat 5/23

2:43 pm-10:23 am

2 stops18h 40m

$798

LouisvilleGuayaquil

SDF - GYE

SDFGYE

Louisville Intl

Fri 8/21

6:00 am-10:45 pm

1 stop17h 45m

Guayaquil Jose Joaquin de Olmedo

Sat 8/29

6:00 am-11:44 pm

1 stop16h 44m

$846

LouisvilleGuayaquil

SDF - GYE

SDFGYE

Louisville Intl

Fri 8/28

6:15 am-11:38 pm

2 stops18h 23m

Guayaquil Jose Joaquin de Olmedo

Tue 9/8

2:37 pm-9:15 am

2 stops17h 38m

$936

LouisvilleGuayaquil

SDF - GYE

SDFGYE

Louisville Intl

Thu 5/14

8:45 am-11:36 pm

2 stops15h 51m

Guayaquil Jose Joaquin de Olmedo

Sun 5/17

12:22 pm-9:59 pm

2 stops32h 37m

$987
Cheapest one-way

LouisvilleGuayaquil

SDF - GYE

SDFGYE

Louisville Intl

Sat 5/16

5:50 am-12:01 am

2 stops19h 11m

$350
Quickest one-way

LouisvilleGuayaquil

SDF - GYE

SDFGYE

Louisville Intl

Sat 5/16

6:06 am-1:31 pm

1 stop8h 25m

$501

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/26

Sorted by cheapest first

Compare providers for flights from Louisville to Guayaquil

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Guayaquil in April.
ProviderPrice AccuracyTrust Score*
OvagoPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Louisville-Guayaquil flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Louisville-Guayaquil flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Louisville-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Louisville-Guayaquil flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Guayaquil?

    There are many flights that can get you from Louisville to Guayaquil in 17h 28m. Fly via American Airlines or United Airlines to get the fastest option. Louisville and Guayaquil are separated by a distance of 2810 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Louisville to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Louisville to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Guayaquil.

  • Can I find deals for business class flights from Louisville to Guayaquil?

    Yes. Cheapflights offers flight deals from Louisville to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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