$339+ Cheap flights from Louisville (SDF) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — GYE
Oct 26 — Nov 21
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to Guayaquil
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Best
One-way
Cheapest flights from Louisville to GuayaquilExplore the most affordable flight options available from Louisville to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 26, 2026.
Explore the most affordable flight options available from Louisville to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 26, 2026.
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:35 pm -
2 stops21h 59m
Sun 11/83:34 pm -
2 stops18h 04m
Deal found 9/22![American Airlines logo]()
$671
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:10 pm -
2 stops20h 24m
Sun 11/86:00 am -
1 stop18h 23m
Deal found 9/22![American Airlines logo]()
$696
Best flights from Louisville to GuayaquilDiscover carefully curated flight deals from Louisville to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 26, 2026.
Discover carefully curated flight deals from Louisville to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 26, 2026.
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:35 pm -
2 stops21h 59m
Sun 11/83:34 pm -
2 stops18h 04m
Deal found 9/22![American Airlines logo]()
$671
This LATAM Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/253:24 pm -
2 stops23h 26m
Thu 1/289:05 am -
2 stops14h 57m
Deal found 9/21![LATAM Airlines logo]()
$901
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/216:01 am -
1 stop8h 30m
Sun 2/283:31 pm -
2 stops23h 32m
Deal found 9/25![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/36:00 am -
1 stop17h 37m
Tue 2/96:00 am -
2 stops14h 34m
Deal found 9/25![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:10 pm -
2 stops20h 24m
Sun 11/83:34 pm -
2 stops21h 09m
Deal found 9/21![American Airlines logo]()
$696
One-way flights from Louisville to GuayaquilSearch for one-way flight options from Louisville to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 26, 2026.
Search for one-way flight options from Louisville to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:22 pm -
2 stops28h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop17h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![American Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:56 pm -
3 stops44h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$412
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
1 stop8h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![American Airlines logo]()
$480
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:25 am -
3 stops38h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$587
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop17h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![American Airlines logo]()
$639
Find flight deals from Louisville to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 26, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $671 (American Airlines) |
One-way from | $339 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 26, 2026.
Use the filters below to find and compare flights from Louisville to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleGuayaquil
SDF Louisville Intl - GYE Guayaquil Jose Joaquin de Olmedo
SDFGYE
Louisville Intl
Thu 10/15
9:22 pm-1:12 am
2 stops28h 50m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$339
LouisvilleGuayaquil
SDF Louisville Intl - GYE Guayaquil Jose Joaquin de Olmedo
SDFGYE
Louisville Intl
Mon 10/12
7:15 am-10:39 pm
2 stops16h 24m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$374
LouisvilleGuayaquil
SDF Louisville Intl - GYE Guayaquil Jose Joaquin de Olmedo
SDFGYE
Louisville Intl
Tue 10/13
6:00 am-10:39 pm
1 stop17h 39m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$374
LouisvilleGuayaquil
SDF Louisville Intl - GYE Guayaquil Jose Joaquin de Olmedo
SDFGYE
Louisville Intl
Tue 10/13
3:56 pm-11:21 am
3 stops44h 25m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$412
Quickest round-trip
LouisvilleGuayaquil
SDF Louisville Intl - GYE Guayaquil Jose Joaquin de Olmedo
SDFGYE
Louisville Intl
Thu 10/15
6:00 am-1:29 pm
1 stop8h 29m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$480
LouisvilleGuayaquil
SDF Louisville Intl - GYE Guayaquil Jose Joaquin de Olmedo
SDFGYE
Louisville Intl
Wed 11/4
4:35 pm-2:34 pm
2 stops21h 59m
Guayaquil Jose Joaquin de Olmedo
Sun 11/8
3:34 pm-9:38 am
2 stops18h 04m
$671
LouisvilleGuayaquil
SDF Louisville Intl - GYE Guayaquil Jose Joaquin de Olmedo
SDFGYE
Louisville Intl
Sun 2/21
6:01 am-2:31 pm
1 stop8h 30m
Guayaquil Jose Joaquin de Olmedo
Sun 2/28
3:31 pm-3:03 pm
2 stops23h 32m
$691
LouisvilleGuayaquil
SDF Louisville Intl - GYE Guayaquil Jose Joaquin de Olmedo
SDFGYE
Louisville Intl
Wed 2/3
6:00 am-11:37 pm
1 stop17h 37m
Guayaquil Jose Joaquin de Olmedo
Tue 2/9
6:00 am-8:34 pm
2 stops14h 34m
$691
LouisvilleGuayaquil
SDF Louisville Intl - GYE Guayaquil Jose Joaquin de Olmedo
SDFGYE
Louisville Intl
Thu 11/5
6:10 pm-2:34 pm
2 stops20h 24m
Guayaquil Jose Joaquin de Olmedo
Sun 11/8
3:34 pm-12:43 pm
2 stops21h 09m
$696
LouisvilleGuayaquil
SDF Louisville Intl - GYE Guayaquil Jose Joaquin de Olmedo
SDFGYE
Louisville Intl
Mon 1/25
3:24 pm-2:50 pm
2 stops23h 26m
Guayaquil Jose Joaquin de Olmedo
Thu 1/28
9:05 am-12:02 am
2 stops14h 57m
$901
Sorted by cheapest first
Compare providers for flights from Louisville to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Guayaquil in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-Guayaquil flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Louisville-Guayaquil flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Louisville-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-Guayaquil flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Louisville with our price prediction graph.
SDF-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Louisville to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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