HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Cruz de la Sierra

$274+ Cheap flights from O'Hare Intl (ORD) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — VVI
Jun 28 — Jul 51
Sat 6/28
Sat 7/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from O'Hare Intl to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from O'Hare Intl to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 23, 2025.

Round-trip from

$613
(Copa Airlines)

One-way from

$274
(United Airlines)

Popular in

July

Cheapest in

April

Average price

$758
From Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($86 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from O'Hare Intl to Santa Cruz de la Sierra

Cheapest flights from O'Hare Intl to Santa Cruz de la Sierra
Explore the most affordable flight options available from O'Hare Intl to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2025.

This Copa Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/67:55 amORD - VVI
1 stop13h 24mCopa Airlines
Tue 8/121:09 amVVI - ORD
1 stop13h 32mCopa Airlines
Deal found 6/22$613
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/610:35 amORD - VVI
2 stops34h 44mUnited Airlines
Tue 8/121:09 amVVI - ORD
2 stops24h 06mUnited Airlines
Deal found 6/22$666
This Avianca deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/510:54 amORD - VVI
2 stops13h 56mAvianca
Mon 8/112:55 amVVI - ORD
1 stop11h 20mAvianca
Deal found 6/21$703
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/57:55 amORD - VVI
1 stop13h 24mMultiple Airlines
Mon 8/112:55 amVVI - ORD
1 stop11h 20mMultiple Airlines
Deal found 6/21$779
This eDestinos deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:10 pmORD - VVI
2 stops32h 25mLATAM Airlines
Fri 1/25:25 amVVI - ORD
2 stops33h 12mLATAM Airlines
Deal found 6/21$3,127

Cheapflights Fare Finder

Customize your flight search to find flights from O'Hare Intl to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra that are best for you.

Fly from

O'Hare Intl

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 8/6

7:55 am-10:19 pm

1 stop13h 24m

Santa Cruz de la Sierra Viru Viru Intl

Tue 8/12

1:09 am-1:41 pm

1 stop13h 32m

$613

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 8/6

10:35 am-10:19 pm

2 stops34h 44m

Santa Cruz de la Sierra Viru Viru Intl

Tue 8/12

1:09 am-12:15 am

2 stops24h 06m

$666

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Tue 8/5

10:54 am-1:50 am

2 stops13h 56m

Santa Cruz de la Sierra Viru Viru Intl

Mon 8/11

2:55 am-1:15 pm

1 stop11h 20m

$703

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Tue 8/5

7:55 am-10:19 pm

1 stop13h 24m

Santa Cruz de la Sierra Viru Viru Intl

Mon 8/11

2:55 am-1:15 pm

1 stop11h 20m

$779

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 12/19

6:10 pm-4:35 am

2 stops32h 25m

Santa Cruz de la Sierra Viru Viru Intl

Fri 1/2

5:25 am-12:37 pm

2 stops33h 12m

$3,127

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Tue 8/5

9:07 pm-10:19 pm

2 stops24h 12m

$274

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 7/16

8:09 am-1:50 am

2 stops40h 41m

$313

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 7/25

1:07 am-10:19 pm

1 stop20h 12m

$454

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sat 7/19

5:25 pm-1:50 am

3 stops31h 25m

$491

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/21

Best time to book a flight from O'Hare Intl to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra (average of $597). Flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to VVI?

Find hourly flight availability from O'Hare Intl to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 23, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 11% on flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra by exploring options for tickets in the morning.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated June 23, 2025.
LATAM Airlines
7.5
Good
1,791 reviews

Crew

8.1

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Overall

7.5

Food

6.7

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
LATAM Airlines
7.5
Good
1,791 reviews
LATAM Airlines
7.5
Good
1,791 reviews

Crew

8.1

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Overall

7.5

Food

6.7

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Copa Airlines
7.5
Good
1,460 reviews
LATAM Airlines
7.5
Good
1,791 reviews

Crew

8.1

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Overall

7.5

Food

6.7

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
United Airlines
7.4
Good
8,831 reviews
LATAM Airlines
7.5
Good
1,791 reviews

Crew

8.1

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Overall

7.5

Food

6.7

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Avianca
6.7
Okay
2,352 reviews
LATAM Airlines
7.5
Good
1,791 reviews

Crew

8.1

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Overall

7.5

Food

6.7

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Chicago O'Hare Intl?

    Santa Cruz de la Sierra Viru Viru Intl (VVI), located 11.5 mi from the city center, is the airport you fly into when you book flights from Chicago O'Hare Intl to Santa Cruz de la Sierra. 2 airlines have flights to Viru Viru Intl from Chicago O'Hare Intl on a regular basis. Booking flights from Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl should not be difficult; the airport handles an average of 0 inbound flights from Chicago O'Hare Intl per day.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra round-trip?

    Our cheapest airline available from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra is Copa Airlines. Our recent data shows that you can find tickets from as low as $613 on this airline. Additional options worth looking into are United Airlines and Avianca, starting at $666 and $703 round-trip. You may be able to fly from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra for 17% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra one-way?

    $274 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Copa Airlines and Avianca, with prices starting from $454 and $491, respectively.

  • Can I find deals for flights from O'Hare Intl to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from O'Hare Intl to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra (average of $597). Flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for O'Hare Intl to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to La Paz flights
O'Hare Intl to Cochabamba flights

Top 2 airlines flying from O'Hare Intl to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from O'Hare Intl to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$566Average$779FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$598Average$711FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.