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Santa Cruz de la Sierra

$351+ Cheap flights from O'Hare Intl (ORD) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — VVI
May 27 — Jun 31
Wed 5/27
Wed 6/3
1 adult, Economy
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Cheap flight deals from O'Hare Intl to Santa Cruz de la Sierra

Cheapest flights from O'Hare Intl to Santa Cruz de la Sierra
Explore the most affordable flight options available from O'Hare Intl to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.

This Avianca deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:46 am
ORD
-
VVI
2 stops14h 44m
Multiple Airlines
Sat 5/93:35 am
VVI
-
ORD
1 stop18h 45m
Multiple Airlines
Deal found 4/23$652
This Trip.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:20 pm
ORD
-
VVI
1 stop26h 10m
Avianca
Sat 5/93:35 am
VVI
-
ORD
1 stop18h 45m
Avianca
Deal found 4/26$672
This FlightHub deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:20 pm
ORD
-
VVI
1 stop26h 10m
Avianca
Sat 10/103:35 am
VVI
-
ORD
1 stop18h 45m
Avianca
Deal found 4/26$674
This Avianca deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:20 pm
ORD
-
VVI
1 stop26h 10m
Avianca
Sat 5/93:35 am
VVI
-
ORD
1 stop18h 45m
Avianca
Deal found 4/22$700
This Avianca deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:20 pm
ORD
-
VVI
1 stop26h 10m
Avianca
Wed 5/203:35 am
VVI
-
ORD
1 stop18h 45m
Avianca
Deal found 4/25$708
This FlightHub deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:20 pm
ORD
-
VVI
1 stop26h 10m
Avianca
Tue 5/263:35 am
VVI
-
ORD
1 stop18h 45m
Avianca
Deal found 4/26$722
This Justfly.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1011:20 pm
ORD
-
VVI
1 stop26h 10m
Avianca
Tue 6/163:35 am
VVI
-
ORD
1 stop18h 45m
Avianca
Deal found 4/27$726
This Avianca deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:40 am
ORD
-
VVI
2 stops16h 50m
Avianca
Fri 6/53:35 am
VVI
-
ORD
1 stop18h 45m
Avianca
Deal found 4/26$742
This Avianca deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:50 am
ORD
-
VVI
2 stops14h 40m
Multiple Airlines
Sat 9/263:35 am
VVI
-
ORD
1 stop18h 45m
Multiple Airlines
Deal found 4/23$746

Find flight deals from O'Hare Intl to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 27, 2026.

Most accurate provider

Ovago
2 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$674
(FlightHub)

One-way from

$351
(Copa Airlines)

Popular in

July

Cheapest in

October

Average price

$613
Provider with most accurate pricing for Chicago O'Hare Intl-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago O'Hare Intl-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($41 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 8/14

10:50 am-2:30 am

2 stops14h 40m

Santa Cruz de la Sierra Viru Viru Intl

Sun 8/23

3:35 am-9:20 pm

1 stop18h 45m

$734

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 5/29

8:40 am-2:30 am

2 stops16h 50m

Santa Cruz de la Sierra Viru Viru Intl

Fri 6/5

3:35 am-9:20 pm

1 stop18h 45m

$742

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 9/11

10:50 am-2:30 am

2 stops14h 40m

Santa Cruz de la Sierra Viru Viru Intl

Sat 9/26

3:35 am-9:20 pm

1 stop18h 45m

$746

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 5/27

8:02 am-10:38 pm

1 stop13h 36m

Santa Cruz de la Sierra Viru Viru Intl

Sat 6/6

11:47 am-4:00 am

1 stop17h 13m

$750
Quickest round-trip

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 9/23

8:01 am-10:44 pm

1 stop13h 43m

Santa Cruz de la Sierra Viru Viru Intl

Tue 9/29

11:47 am-1:02 am

1 stop14h 15m

$750

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sat 9/26

10:45 am-2:30 am

2 stops14h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/10

3:35 am-9:20 pm

1 stop18h 45m

$753

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 5/27

6:02 am-10:38 pm

2 stops15h 36m

Santa Cruz de la Sierra Viru Viru Intl

Sat 6/6

11:47 am-9:22 am

2 stops22h 35m

$775

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 5/29

9:55 pm-10:38 pm

2 stops23h 43m

Santa Cruz de la Sierra Viru Viru Intl

Sat 6/6

11:47 am-9:36 am

2 stops22h 49m

$775
Cheapest one-way
Quickest one-way

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mon 6/1

3:21 pm-3:31 am

1 stop11h 10m

$351

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 6/5

3:21 pm-3:31 am

1 stop11h 10m

$351

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Compare providers for flights from O'Hare Intl to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Santa Cruz de la Sierra in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flight deals on Cheapflights vs. Ovago 90-95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra (average of $581). Flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra in July is currently the most expensive (average of $868). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated April 27, 2026.
Read reviews from past customers who have flown Copa Airlines and United Airlines from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,580 reviews

Comfort

7.4

Boarding

7.8

Crew

8.1

Overall

7.5

Food

6.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,580 reviews
Copa Airlines
7.5
Good
1,580 reviews

Comfort

7.4

Boarding

7.8

Crew

8.1

Overall

7.5

Food

6.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
United Airlines
7.4
Good
9,668 reviews
Copa Airlines
7.5
Good
1,580 reviews

Comfort

7.4

Boarding

7.8

Crew

8.1

Overall

7.5

Food

6.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Chicago O'Hare Intl?

    Santa Cruz de la Sierra Viru Viru Intl (VVI), located 11.5 mi from the city center, is the airport you fly into when you book flights from Chicago O'Hare Intl to Santa Cruz de la Sierra. 2 airlines have flights to Viru Viru Intl from Chicago O'Hare Intl on a regular basis. Booking flights from Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl should not be difficult; the airport handles an average of 0 inbound flights from Chicago O'Hare Intl per day.

  • How long is the flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

    A quick flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra can take about 13h 36m. Avianca provides one of the quickest options available for as low as $750. The distance from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra is about 4410 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra round-trip?

    Our cheapest airline available from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra is United Airlines. Our recent data shows that you can find tickets from as low as $278 on this airline. An additional option worth looking into is Copa Airlines, starting at $458. You may be able to fly from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra for 58% less than the average price by searching for these airlines.

  • Can I find deals for flights from O'Hare Intl to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from O'Hare Intl to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra (average of $581). Flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra in July is currently the most expensive (average of $868). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for O'Hare Intl to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to La Paz flights

Top 2 airlines flying from O'Hare Intl to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from O'Hare Intl to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$278Average$603FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$458Average$723FlexibilityNo cancel feeOn-time70%

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