HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Cruz de la Sierra

$259+ Cheap flights from O'Hare Intl (ORD) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/23. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — VVI
Aug 26 — Sep 21
Wed 8/26
Wed 9/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from O'Hare Intl to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from O'Hare Intl to Santa Cruz de la Sierra

Cheapest flights from O'Hare Intl to Santa Cruz de la Sierra
Explore the most affordable flight options available from O'Hare Intl to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

This Copa Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:35 am
ORD
-
VVI
1 stop18h 02m
Copa Airlines
Tue 11/1711:49 am
VVI
-
ORD
1 stop14h 22m
Copa Airlines
Deal found 7/24$568
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:42 pm
ORD
-
VVI
2 stops27h 55m
United Airlines
Tue 11/1711:49 am
VVI
-
ORD
3 stops34h 51m
United Airlines
Deal found 7/23$573
This United deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:00 am
ORD
-
VVI
2 stops38h 40m
Multiple Airlines
Thu 10/293:40 am
VVI
-
ORD
2 stops30h 54m
Multiple Airlines
Deal found 7/24$581
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:30 am
ORD
-
VVI
2 stops19h 08m
United Airlines
Sat 10/2411:47 am
VVI
-
ORD
2 stops24h 47m
United Airlines
Deal found 7/23$583
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:35 pm
ORD
-
VVI
2 stops29h 05m
United Airlines
Wed 11/1111:49 am
VVI
-
ORD
2 stops23h 45m
United Airlines
Deal found 7/23$591
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am
ORD
-
VVI
2 stops21h 10m
United Airlines
Wed 11/1111:49 am
VVI
-
ORD
2 stops21h 41m
United Airlines
Deal found 7/27$593
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
ORD
-
VVI
2 stops39h 44m
United Airlines
Thu 9/1711:47 am
VVI
-
ORD
3 stops51h 40m
United Airlines
Deal found 7/27$608
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:52 pm
ORD
-
VVI
2 stops28h 46m
United Airlines
Sat 10/2411:47 am
VVI
-
ORD
2 stops24h 47m
United Airlines
Deal found 7/23$621
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/139:35 pm
ORD
-
VVI
2 stops29h 00m
United Airlines
Mon 8/2411:47 am
VVI
-
ORD
2 stops25h 12m
United Airlines
Deal found 7/22$629
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:45 pm
ORD
-
VVI
2 stops30h 50m
United Airlines
Thu 8/2011:47 am
VVI
-
ORD
2 stops38h 12m
United Airlines
Deal found 7/22$630

Find flight deals from O'Hare Intl to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 27, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$568
(Copa Airlines)

One-way from

$259
(United)

Popular in

July

Cheapest in

October

Average price

$977
Provider with most accurate pricing for Chicago O'Hare Intl-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago O'Hare Intl-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($210 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sun 11/1

7:35 am-3:37 am

1 stop18h 02m

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/17

11:49 am-12:11 am

1 stop14h 22m

$568

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 9/9

3:20 pm-10:44 pm

1 stop30h 24m

Santa Cruz de la Sierra Viru Viru Intl

Tue 9/15

1:12 am-1:02 am

1 stop24h 50m

$568
Quickest round-trip

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 10/23

3:20 pm-3:38 am

1 stop11h 18m

Santa Cruz de la Sierra Viru Viru Intl

Thu 10/29

1:12 am-1:46 pm

1 stop13h 34m

$568

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sun 8/30

7:00 am-10:40 pm

2 stops38h 40m

Santa Cruz de la Sierra Viru Viru Intl

Thu 10/29

3:40 am-9:34 am

2 stops30h 54m

$581

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mon 9/14

5:00 am-10:44 pm

2 stops40h 44m

Santa Cruz de la Sierra Viru Viru Intl

Thu 9/17

11:47 am-12:28 am

2 stops37h 41m

$583

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Tue 10/6

9:38 pm-3:38 am

2 stops29h 00m

Santa Cruz de la Sierra Viru Viru Intl

Mon 10/19

11:47 am-7:25 am

2 stops20h 38m

$583

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 10/7

7:15 am-3:38 am

3 stops19h 23m

Santa Cruz de la Sierra Viru Viru Intl

Mon 10/19

11:47 am-11:48 am

2 stops25h 01m

$583

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mon 10/26

7:15 am-3:40 am

2 stops19h 25m

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/12

11:49 am-9:34 am

2 stops23h 45m

$583

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sat 10/10

9:38 pm-10:44 pm

2 stops24h 06m

Santa Cruz de la Sierra Viru Viru Intl

Mon 10/19

11:47 am-7:25 am

2 stops20h 38m

$583

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mon 10/5

7:15 am-3:38 am

3 stops19h 23m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/24

11:47 am-11:34 am

2 stops24h 47m

$583

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/24

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from O'Hare Intl to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Santa Cruz de la Sierra in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
OvagoPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra (average of $581). Flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra in July is currently the most expensive (average of $977). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated July 27, 2026.
Read reviews from past customers who have flown Copa Airlines and United Airlines from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,561 reviews

Overall

7.6

Crew

8.1

Comfort

7.4

Food

6.9

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jul 2026

BOS - PTY

Airline was delayed 1 hour, that made my layover flight be missed, gave wrong information about gates, they closed the gates in my face, rebooked me, and had business class, and rebooked me not business class
Copa Airlines
7.6
Good
1,561 reviews
Copa Airlines
7.6
Good
1,561 reviews

Overall

7.6

Crew

8.1

Comfort

7.4

Food

6.9

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jul 2026

BOS - PTY

Airline was delayed 1 hour, that made my layover flight be missed, gave wrong information about gates, they closed the gates in my face, rebooked me, and had business class, and rebooked me not business class
United Airlines
7.4
Good
10,042 reviews
Copa Airlines
7.6
Good
1,561 reviews

Overall

7.6

Crew

8.1

Comfort

7.4

Food

6.9

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jul 2026

BOS - PTY

Airline was delayed 1 hour, that made my layover flight be missed, gave wrong information about gates, they closed the gates in my face, rebooked me, and had business class, and rebooked me not business class

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Chicago O'Hare Intl?

    Santa Cruz de la Sierra Viru Viru Intl (VVI), located 11.5 mi from the city center, is the airport you fly into when you book flights from Chicago O'Hare Intl to Santa Cruz de la Sierra. 2 airlines have flights to Viru Viru Intl from Chicago O'Hare Intl on a regular basis. Booking flights from Chicago O'Hare Intl to Santa Cruz de la Sierra Viru Viru Intl should not be difficult; the airport handles an average of 0 inbound flights from Chicago O'Hare Intl per day.

  • How long is the flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

    A quick flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra can take about 18h 02m. Copa Airlines provides one of the quickest options available for as low as $568. The distance from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra is about 4410 mi.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra round-trip?

    Our cheapest airline available from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra is Copa Airlines. Our recent data shows that you can find tickets from as low as $458 on this airline. An additional option worth looking into is United Airlines, starting at $506. You may be able to fly from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra for 37% less than the average price by searching for these airlines.

  • Can I find deals for flights from O'Hare Intl to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from O'Hare Intl to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra (average of $581). Flying from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra in July is currently the most expensive (average of $977). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for O'Hare Intl to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to La Paz flights

Top 2 airlines flying from O'Hare Intl to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from O'Hare Intl to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$458Average$820FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$506Average$624FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.