$712+ Cheap flights from Santa Cruz de la Sierra (VVI) to O'Hare Intl (ORD)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — ORD
Oct 8 — Oct 151
Round-trip
1 adult, Economy
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Find cheap flights from Santa Cruz de la Sierra to O'Hare Intl with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Cruz de la Sierra to O'Hare Intl
Cheapest
Best
Last-minute
Cheapest flights from Santa Cruz de la Sierra to O'Hare IntlExplore the most affordable flight options available from Santa Cruz de la Sierra to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
Explore the most affordable flight options available from Santa Cruz de la Sierra to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
This Booking.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/211:08 am -
1 stop13h 38m
Sun 11/297:35 am -
1 stop18h 02m
Deal found 9/7![Copa Airlines logo]()
$712
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:49 am -
1 stop14h 22m
Sun 11/297:35 am -
1 stop18h 02m
Deal found 9/5![Copa Airlines logo]()
$716
This United deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:45 am -
2 stops32h 26m
Sun 11/296:50 am -
2 stops18h 47m
Deal found 9/5![Multiple Airlines logo]()
$767
This Mytrip deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:00 pm -
2 stops28h 13m
Sun 11/292:13 pm -
1 stop30h 25m
Deal found 9/7![Multiple Airlines logo]()
$841
This Avianca deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:35 am -
1 stop18h 45m
Mon 9/2111:20 pm -
1 stop26h 10m
Deal found 9/4![Avianca logo]()
$1,012
This eDestinos deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:45 am -
2 stops17h 10m
Sun 11/2910:30 pm -
1 stop26h 10m
Deal found 9/5![Avianca logo]()
$1,284
Best flights from Santa Cruz de la Sierra to O'Hare IntlDiscover carefully curated flight deals from Santa Cruz de la Sierra to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
Discover carefully curated flight deals from Santa Cruz de la Sierra to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
This Booking.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/211:08 am -
1 stop13h 38m
Sun 11/297:35 am -
1 stop18h 02m
Deal found 9/7![Copa Airlines logo]()
$712
This United deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:45 am -
2 stops32h 26m
Sun 11/2911:55 pm -
2 stops25h 47m
Deal found 9/7![Multiple Airlines logo]()
$767
This Avianca deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:35 am -
1 stop18h 45m
Mon 9/2111:20 pm -
1 stop26h 10m
Deal found 9/4![Avianca logo]()
$1,012
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2211:55 am -
2 stops23h 44m
Mon 3/88:55 am -
2 stops17h 56m
Deal found 9/8![United Airlines logo]()
$1,229
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:49 am -
1 stop14h 22m
Sun 11/297:35 am -
1 stop18h 02m
Deal found 9/5![Copa Airlines logo]()
$716
Last-minute flights from Santa Cruz de la Sierra to O'Hare IntlDiscover last-minute flight deals from Santa Cruz de la Sierra to O'Hare Intl. Data last updated September 8, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Cruz de la Sierra to O'Hare Intl. Data last updated September 8, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:35 am -
1 stop18h 45m
Mon 9/2111:20 pm -
1 stop26h 10m
Deal found 9/4![Avianca logo]()
$1,012
Find flight deals from Santa Cruz de la Sierra to O'Hare Intl
Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to O'Hare Intl (ORD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $712 (Booking.com) |
Popular in | February |
Cheapest in | July |
Average price | $827 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Cruz de la Sierra to O'Hare Intl that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Santa Cruz de la SierraChicago
VVI Santa Cruz de la Sierra Viru Viru Intl - ORD Chicago O'Hare Intl
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Sat 11/21
1:08 am-12:46 pm
1 stop13h 38m
Chicago O'Hare Intl
Sun 11/29
7:35 am-3:37 am
1 stop18h 02m
$712
Santa Cruz de la SierraChicago
VVI Santa Cruz de la Sierra Viru Viru Intl - ORD Chicago O'Hare Intl
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Sat 11/14
11:49 am-12:11 am
1 stop14h 22m
Chicago O'Hare Intl
Sun 11/29
7:35 am-3:37 am
1 stop18h 02m
$716
Santa Cruz de la SierraChicago
VVI Santa Cruz de la Sierra Viru Viru Intl - ORD Chicago O'Hare Intl
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Sat 11/21
3:45 am-10:11 am
2 stops32h 26m
Chicago O'Hare Intl
Sun 11/29
11:55 pm-3:42 am
2 stops25h 47m
$767
Santa Cruz de la SierraChicago
VVI Santa Cruz de la Sierra Viru Viru Intl - ORD Chicago O'Hare Intl
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Thu 9/17
3:35 am-9:20 pm
1 stop18h 45m
Chicago O'Hare Intl
Mon 9/21
11:20 pm-2:30 am
1 stop26h 10m
$1,012
Santa Cruz de la SierraChicago
VVI Santa Cruz de la Sierra Viru Viru Intl - ORD Chicago O'Hare Intl
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Mon 2/22
11:55 am-9:39 am
2 stops23h 44m
Chicago O'Hare Intl
Mon 3/8
8:55 am-4:51 am
2 stops17h 56m
$1,229
Sorted by cheapest first
Compare providers for flights from Santa Cruz de la Sierra to O'Hare Intl
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Cruz de la Sierra to O'Hare Intl in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-Chicago O'Hare Intl Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Cruz de la Sierra-Chicago O'Hare Intl Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-Chicago O'Hare Intl Airport flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-Chicago O'Hare Intl Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-Chicago O'Hare Intl Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Cruz de la Sierra to O'Hare Intl
Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Santa Cruz de la Sierra with our price prediction graph.
VVI-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport
What’s the top layover airport for flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport?
Share of 1-stop round-trip flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 50% of 1-stop itineraries from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport on Cheapflights.
What’s the cheapest layover airport for flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport?
Average round-trip fare for 1-stop flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $725.
What’s the fastest layover option from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport?
Shortest average travel time for 1-stop one-way flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 13h 43m.
Which airport typically offers the quickest layover for flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport?
Average layover duration for 1-stop one-way flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 3h 12m.
Reviews of airlines servicing O'Hare Intl
Get insights into the airlines that provide service to O'Hare Intl. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to O'Hare Intl. Reviews last updated September 8, 2026.
Get a feel of what it's like to fly with Copa Airlines from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Entertainment
6.9
Food
6.9
Overall
7.6
Comfort
7.4
Boarding
7.8
Reviews
1 / 20
4.0
OkayPaul,Jun 2025
PTY - MIA
Crew
8.1
Entertainment
6.9
Food
6.9
Overall
7.6
Comfort
7.4
Boarding
7.8
Reviews
1 / 20
4.0
OkayPaul,Jun 2025
PTY - MIA
Related info for your journey
Find useful and relevant information for your journey from Santa Cruz de la Sierra to O'Hare Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago O'Hare Intl Airport?
Book flights to Chicago O'Hare Intl Airport if you plan to visit one of these locationsBenton Harbor
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Top airline flying from Santa Cruz de la Sierra to O'Hare Intl
Discover the top airline that operate flights from Santa Cruz de la Sierra to O'Hare Intl. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$506 | Average$913 | FlexibilityNo cancel fee | On-time70% |