$160+ Cheap flights from O'Hare Intl (ORD) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — GYE
Jul 26 — Aug 21
Round-trip
1 adult, Economy
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Cheapest flights from O'Hare Intl to GuayaquilExplore the most affordable flight options available from O'Hare Intl to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 26, 2026.
Explore the most affordable flight options available from O'Hare Intl to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 26, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am
ORD
- GYE
1 stop9h 14m
JetBlue
Wed 9/2312:30 pm
GYE
- ORD
1 stop11h 01m
JetBlue
Deal found 6/23![JetBlue logo]()
$395
This Ovago deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:00 am
ORD
- GYE
1 stop8h 22m
JetBlue
Fri 10/212:30 pm
GYE
- ORD
1 stop11h 01m
JetBlue
Deal found 6/25![JetBlue logo]()
$402
This JetBlue deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:00 am
ORD
- GYE
1 stop8h 22m
JetBlue
Sat 9/2612:30 pm
GYE
- ORD
1 stop11h 01m
JetBlue
Deal found 6/24![JetBlue logo]()
$403
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:05 pm
ORD
- GYE
1 stop18h 28m
American Airlines
Wed 11/46:00 am
GYE
- ORD
2 stops12h 55m
American Airlines
Deal found 6/23![American Airlines logo]()
$407
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
ORD
- GYE
1 stop12h 55m
American Airlines
Tue 10/202:30 pm
GYE
- ORD
1 stop20h 33m
American Airlines
Deal found 6/24![American Airlines logo]()
$410
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:34 am
ORD
- GYE
2 stops12h 21m
American Airlines
Mon 10/192:30 pm
GYE
- ORD
1 stop18h 23m
American Airlines
Deal found 6/23![American Airlines logo]()
$415
This Cheapflightsfares deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:00 am
ORD
- GYE
1 stop8h 22m
JetBlue
Sat 10/241:30 pm
GYE
- ORD
1 stop10h 14m
JetBlue
Deal found 6/24![JetBlue logo]()
$424
This KAYAK deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:35 pm
ORD
- GYE
1 stop24h 47m
JetBlue
Wed 9/3012:30 pm
GYE
- ORD
1 stop11h 01m
JetBlue
Deal found 6/25![JetBlue logo]()
$425
This Ovago deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
ORD
- GYE
1 stop9h 14m
JetBlue
Fri 9/1812:30 pm
GYE
- ORD
1 stop11h 01m
JetBlue
Deal found 6/20![JetBlue logo]()
$431
This JetBlue deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
ORD
- GYE
1 stop9h 14m
JetBlue
Sun 9/2712:30 pm
GYE
- ORD
1 stop11h 01m
JetBlue
Deal found 6/24![JetBlue logo]()
$433
Best flights from O'Hare Intl to GuayaquilDiscover carefully curated flight deals from O'Hare Intl to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 26, 2026.
Discover carefully curated flight deals from O'Hare Intl to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 26, 2026.
This JetBlue deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:00 am
ORD
- GYE
1 stop8h 22m
JetBlue
Mon 9/2112:30 pm
GYE
- ORD
1 stop11h 01m
JetBlue
Deal found 6/24![JetBlue logo]()
$403
This Copa Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:02 am
ORD
- GYE
1 stop16h 00m
Copa Airlines
Mon 8/314:13 am
GYE
- ORD
1 stop20h 49m
Copa Airlines
Deal found 6/22![Copa Airlines logo]()
$510
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:02 am
ORD
- GYE
1 stop9h 29m
Multiple Airlines
Tue 7/2110:05 am
GYE
- ORD
2 stops26h 10m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:29 am
ORD
- GYE
2 stops17h 09m
United Airlines
Wed 9/212:22 pm
GYE
- ORD
2 stops20h 47m
United Airlines
Deal found 6/21![United Airlines logo]()
$600
This JetBlue deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:00 am
ORD
- GYE
1 stop8h 22m
JetBlue
Mon 9/2112:30 pm
GYE
- ORD
1 stop11h 01m
JetBlue
Deal found 6/24![JetBlue logo]()
$403
This Copa Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:02 am
ORD
- GYE
1 stop26h 32m
Copa Airlines
Sat 8/292:37 pm
GYE
- ORD
1 stop10h 25m
Copa Airlines
Deal found 6/23![Copa Airlines logo]()
$510
This Expedia deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:00 am
ORD
- GYE
1 stop8h 20m
Multiple Airlines
Mon 10/194:19 pm
GYE
- ORD
2 stops24h 14m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$566
This Copa Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:21 pm
ORD
- GYE
1 stop22h 14m
Copa Airlines
Fri 7/316:27 pm
GYE
- ORD
1 stop19h 32m
Copa Airlines
Deal found 6/25![Copa Airlines logo]()
$528
This JetBlue deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:27 pm
ORD
- GYE
1 stop11h 38m
JetBlue
Fri 9/2512:30 pm
GYE
- ORD
1 stop11h 01m
JetBlue
Deal found 6/24![JetBlue logo]()
$536
This United deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:29 pm
ORD
- GYE
2 stops20h 06m
Multiple Airlines
Mon 8/318:28 am
GYE
- ORD
2 stops23h 27m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$608
This United deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:29 am
ORD
- GYE
2 stops17h 01m
Multiple Airlines
Sun 8/1612:22 pm
GYE
- ORD
2 stops19h 33m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$608
Last-minute flights from O'Hare Intl to GuayaquilDiscover last-minute flight deals from O'Hare Intl to Guayaquil. Data last updated June 26, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to Guayaquil. Data last updated June 26, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:20 pm
ORD
- GYE
1 stop9h 35m
Avianca
Mon 7/2010:05 am
GYE
- ORD
1 stop11h 15m
Avianca
Deal found 6/21![Avianca logo]()
$520
This Avianca deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/411:20 pm
ORD
- GYE
1 stop18h 15m
Avianca
Wed 7/1510:05 am
GYE
- ORD
1 stop11h 15m
Avianca
Deal found 6/25![Avianca logo]()
$523
This Flighttix deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:00 am
ORD
- GYE
1 stop8h 22m
JetBlue
Tue 7/141:27 pm
GYE
- ORD
1 stop10h 17m
JetBlue
Deal found 6/24![JetBlue logo]()
$490
This Copa Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:21 pm
ORD
- GYE
1 stop20h 01m
Copa Airlines
Sun 7/192:36 pm
GYE
- ORD
1 stop13h 24m
Copa Airlines
Deal found 6/21![Copa Airlines logo]()
$510
This Faresmojo deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:00 am
ORD
- GYE
1 stop8h 22m
JetBlue
Tue 7/211:27 pm
GYE
- ORD
1 stop10h 17m
JetBlue
Deal found 6/25![JetBlue logo]()
$496
This Faresmojo deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:00 am
ORD
- GYE
1 stop8h 22m
JetBlue
Wed 7/291:27 pm
GYE
- ORD
1 stop10h 17m
JetBlue
Deal found 6/25![JetBlue logo]()
$481
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:00 pm
ORD
- GYE
1 stop19h 25m
American Airlines
Wed 7/222:25 pm
GYE
- ORD
1 stop18h 43m
American Airlines
Deal found 6/25![American Airlines logo]()
$472
This Avianca deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1611:20 pm
ORD
- GYE
1 stop9h 35m
Avianca
Wed 9/210:05 am
GYE
- ORD
1 stop11h 15m
Avianca
Deal found 6/24![Avianca logo]()
$508
This BusinessClass deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:37 am
ORD
- GYE
2 stops16h 00m
GOL
Thu 7/232:25 pm
GYE
- ORD
2 stops16h 13m
GOL
Deal found 6/22![GOL logo]()
$498
This Cheapflightsfares deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:00 am
ORD
- GYE
1 stop8h 22m
JetBlue
Thu 7/231:27 pm
GYE
- ORD
1 stop10h 17m
JetBlue
Deal found 6/22![JetBlue logo]()
$502
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:21 pm
ORD
- GYE
1 stop8h 41m
Multiple Airlines
Tue 7/2810:05 am
GYE
- ORD
2 stops26h 10m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$521
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/233:21 pm
ORD
- GYE
1 stop8h 41m
Multiple Airlines
Thu 7/3010:05 am
GYE
- ORD
2 stops26h 10m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$522
One-way flights from O'Hare Intl to GuayaquilSearch for one-way flight options from O'Hare Intl to Guayaquil. Find affordable one-way fares based on user searches. Data last updated June 26, 2026.
Search for one-way flight options from O'Hare Intl to Guayaquil. Find affordable one-way fares based on user searches. Data last updated June 26, 2026.
This SmartFares deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:00 am
ORD
- GYE
1 stop8h 22m
JetBlue
Deal found 6/24![JetBlue logo]()
$160
This Cheapflightsfares deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:00 am
ORD
- GYE
1 stop9h 14m
JetBlue
Deal found 6/23![JetBlue logo]()
$167
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am
ORD
- GYE
1 stop15h 39m
American Airlines
Deal found 6/23![American Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:30 am
ORD
- GYE
2 stops17h 07m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:05 am
ORD
- GYE
2 stops16h 33m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:03 pm
ORD
- GYE
2 stops33h 34m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:49 pm
ORD
- GYE
3 stops30h 48m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$225
This Copa Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/203:21 pm
ORD
- GYE
1 stop19h 13m
Copa Airlines
Deal found 6/22![Copa Airlines logo]()
$233
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:53 am
ORD
- GYE
2 stops12h 18m
American Airlines
Deal found 6/23![American Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:45 am
ORD
- GYE
3 stops39h 52m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$238
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
ORD
- GYE
2 stops13h 39m
American Airlines
Deal found 6/23![American Airlines logo]()
$240
Find flight deals from O'Hare Intl to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $395 (Cheapflightsfares) |
One-way from | $160 (SmartFares) |
Popular in | December |
Cheapest in | April |
Average price | $593 |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Sun 8/30
7:00 am-3:22 pm
1 stop8h 22m
Guayaquil Jose Joaquin de Olmedo
Mon 9/21
12:30 pm-11:31 pm
1 stop11h 01m
$403
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Tue 9/1
7:00 am-3:22 pm
1 stop8h 22m
Guayaquil Jose Joaquin de Olmedo
Mon 9/21
12:30 pm-11:31 pm
1 stop11h 01m
$403
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Mon 8/24
8:02 am-12:02 am
1 stop16h 00m
Guayaquil Jose Joaquin de Olmedo
Mon 8/31
4:13 am-1:02 am
1 stop20h 49m
$510
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Sun 8/23
8:02 am-10:34 am
1 stop26h 32m
Guayaquil Jose Joaquin de Olmedo
Sat 8/29
2:37 pm-1:02 am
1 stop10h 25m
$510
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Thu 7/16
3:21 pm-1:35 pm
1 stop22h 14m
Guayaquil Jose Joaquin de Olmedo
Fri 7/31
6:27 pm-1:59 pm
1 stop19h 32m
$528
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Thu 9/3
5:27 pm-5:05 am
1 stop11h 38m
Guayaquil Jose Joaquin de Olmedo
Fri 9/25
12:30 pm-11:31 pm
1 stop11h 01m
$536
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Tue 7/14
8:02 am-5:31 pm
1 stop9h 29m
Guayaquil Jose Joaquin de Olmedo
Tue 7/21
10:05 am-12:15 pm
2 stops26h 10m
$539
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Mon 8/10
7:00 am-3:20 pm
1 stop8h 20m
Guayaquil Jose Joaquin de Olmedo
Mon 10/19
4:19 pm-4:33 pm
2 stops24h 14m
$566
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Thu 7/16
6:29 am-11:38 pm
2 stops17h 09m
Guayaquil Jose Joaquin de Olmedo
Wed 9/2
12:22 pm-9:09 am
2 stops20h 47m
$600
ChicagoGuayaquil
ORD - GYE
ORDGYE
Chicago O'Hare Intl
Mon 8/24
6:29 pm-2:35 pm
2 stops20h 06m
Guayaquil Jose Joaquin de Olmedo
Mon 8/31
8:28 am-7:55 am
2 stops23h 27m
$608
Showing 1-10 of 23 resultsSorted by cheapest first
Compare providers for flights from O'Hare Intl to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Guayaquil in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*2 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from O'Hare Intl to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from O'Hare Intl with our price prediction graph.
ORD-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to Guayaquil
Prices
More
How far ahead should I book a flight from Chicago O'Hare Intl Airport to Guayaquil?
To ensure you get the cheapest price possible for a flight from Chicago O'Hare Intl Airport to Guayaquil, you should look to book at least 18 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Guayaquil?
Currently, April is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Guayaquil (average of $352). Flying from Chicago O'Hare Intl Airport to Guayaquil in December is currently the most expensive (average of $670). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Chicago O'Hare Intl Airport to Guayaquil?
What’s the top layover airport for flights from Chicago O'Hare Intl Airport to Guayaquil?
Share of 1-stop round-trip flights from Chicago O'Hare Intl Airport to Guayaquil chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 75% of 1-stop itineraries from Chicago O'Hare Intl Airport to Guayaquil on Cheapflights.
What’s the cheapest layover airport for flights from Chicago O'Hare Intl Airport to Guayaquil?
Average round-trip fare for 1-stop flights from Chicago O'Hare Intl Airport to Guayaquil, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $595.
What’s the fastest layover option from Chicago O'Hare Intl Airport to Guayaquil?
Shortest average travel time for 1-stop one-way flights from Chicago O'Hare Intl Airport to Guayaquil, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 8h 53m.
Which airport typically offers the quickest layover for flights from Chicago O'Hare Intl Airport to Guayaquil?
Average layover duration for 1-stop one-way flights from Chicago O'Hare Intl Airport to Guayaquil, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 49m.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated June 26, 2026.
Read through reviews of airlines operating flights from Chicago O'Hare Intl Airport to Guayaquil, such as Copa Airlines,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Overall
7.6
Food
6.9
Crew
8.1
Comfort
7.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Boarding
7.8
Overall
7.6
Food
6.9
Crew
8.1
Comfort
7.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Boarding
7.8
Overall
7.6
Food
6.9
Crew
8.1
Comfort
7.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Boarding
7.8
Overall
7.6
Food
6.9
Crew
8.1
Comfort
7.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Boarding
7.8
Overall
7.6
Food
6.9
Crew
8.1
Comfort
7.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Search flights from O'Hare Intl to Guayaquil by cabin class
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 26, 2026.
O'Hare Intl and Guayaquil flights
Browse other O'Hare Intl and Guayaquil flight options. Last updated on June 26, 2026.
Other flights from O'Hare Intl
Browse through other flights departing from O'Hare Intl. Flights are based on user searches made on Cheapflights and were last updated on June 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from O'Hare Intl to Guayaquil
Discover the top 4 airlines that operate flights from O'Hare Intl to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$352 | Average$578 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$374 | Average$546 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$387 | Average$729 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$438 | Average$532 | FlexibilityNo cancel fee | On-time69% |