$208+ Cheap flights from O'Hare Intl (ORD) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — GYE
Sep 23 — Sep 301
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from O'Hare Intl to Guayaquil
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Cheapest flights from O'Hare Intl to GuayaquilExplore the most affordable flight options available from O'Hare Intl to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 24, 2026.
Explore the most affordable flight options available from O'Hare Intl to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:01 am -
1 stop27h 20m
Tue 9/1512:22 pm -
1 stop12h 40m
Deal found 8/19![Copa Airlines logo]()
$465
This Copa Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/142:13 pm -
1 stop8h 42m
Sun 11/292:47 pm -
1 stop22h 59m
Deal found 8/19![Copa Airlines logo]()
$469
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:14 am -
1 stop16h 25m
Sun 10/182:29 pm -
1 stop19h 01m
Deal found 8/22![American Airlines logo]()
$480
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:40 am -
1 stop16h 59m
Sat 10/172:29 pm -
1 stop19h 01m
Deal found 8/19![American Airlines logo]()
$481
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:00 am -
1 stop17h 39m
Mon 10/122:29 pm -
1 stop17h 18m
Deal found 8/21![American Airlines logo]()
$482
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:01 am -
1 stop16h 00m
Tue 10/278:23 am -
1 stop16h 42m
Deal found 8/21![Copa Airlines logo]()
$492
This Copa Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:35 am -
1 stop9h 00m
Sun 11/82:47 pm -
1 stop22h 59m
Deal found 8/19![Copa Airlines logo]()
$493
Best flights from O'Hare Intl to GuayaquilDiscover carefully curated flight deals from O'Hare Intl to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 24, 2026.
Discover carefully curated flight deals from O'Hare Intl to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 24, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/142:13 pm -
1 stop8h 42m
Sun 11/292:47 pm -
1 stop22h 59m
Deal found 8/22![Copa Airlines logo]()
$469
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/262:13 pm -
1 stop8h 42m
Wed 12/912:22 pm -
1 stop25h 24m
Deal found 8/21![Copa Airlines logo]()
$469
This Copa Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:35 am -
1 stop9h 00m
Sun 11/82:47 pm -
1 stop22h 59m
Deal found 8/19![Copa Airlines logo]()
$493
This Copa Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:01 am -
1 stop27h 20m
Wed 9/2312:22 pm -
1 stop12h 40m
Deal found 8/23![Copa Airlines logo]()
$516
This Copa Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:01 am -
1 stop15h 36m
Sat 10/242:33 pm -
1 stop10h 24m
Deal found 8/22![Copa Airlines logo]()
$523
This Copa Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/43:20 pm -
1 stop8h 41m
Sun 10/114:14 am -
1 stop9h 45m
Deal found 8/20![Copa Airlines logo]()
$576
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:01 am -
1 stop16h 00m
Wed 9/166:00 am -
1 stop19h 02m
Deal found 8/21![Copa Airlines logo]()
$638
Last-minute flights from O'Hare Intl to GuayaquilDiscover last-minute flight deals from O'Hare Intl to Guayaquil. Data last updated August 24, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to Guayaquil. Data last updated August 24, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:01 am -
1 stop27h 20m
Tue 9/1512:22 pm -
1 stop12h 40m
Deal found 8/19![Copa Airlines logo]()
$465
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:20 pm -
1 stop8h 17m
Sun 9/202:37 pm -
1 stop10h 25m
Deal found 8/21![Copa Airlines logo]()
$514
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:20 pm -
1 stop8h 17m
Wed 9/169:00 am -
2 stops24h 20m
Deal found 8/21![Multiple Airlines logo]()
$563
This Copa Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:20 pm -
1 stop26h 10m
Tue 9/156:28 pm -
1 stop19h 31m
Deal found 8/19![Copa Airlines logo]()
$516
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:20 pm -
1 stop19h 14m
Sun 9/202:37 pm -
1 stop10h 25m
Deal found 8/21![Copa Airlines logo]()
$559
This JetBlue deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:00 am -
1 stop9h 14m
Wed 9/3012:30 pm -
1 stop10h 38m
Deal found 8/22![JetBlue logo]()
$481
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:01 am -
1 stop9h 29m
Sun 9/202:37 pm -
1 stop10h 25m
Deal found 8/21![Copa Airlines logo]()
$534
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:01 am -
1 stop9h 29m
Fri 9/184:13 am -
1 stop9h 46m
Deal found 8/21![Copa Airlines logo]()
$541
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:20 pm -
1 stop8h 41m
Fri 10/26:30 pm -
2 stops23h 57m
Deal found 8/21![Multiple Airlines logo]()
$555
This Cheapflightsfares deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
1 stop9h 14m
Sun 10/412:30 pm -
1 stop10h 38m
Deal found 8/20![JetBlue logo]()
$538
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:20 pm -
1 stop8h 41m
Mon 10/56:30 pm -
2 stops44h 50m
Deal found 8/20![Multiple Airlines logo]()
$552
One-way flights from O'Hare Intl to GuayaquilSearch for one-way flight options from O'Hare Intl to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 24, 2026.
Search for one-way flight options from O'Hare Intl to Guayaquil. Find affordable one-way fares based on user searches. Data last updated August 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:01 am -
1 stop29h 33m
Deal found 8/19![Copa Airlines logo]()
$208
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:08 am -
2 stops12h 31m
Deal found 8/21![American Airlines logo]()
$210
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:20 pm -
1 stop19h 13m
Deal found 8/21![Copa Airlines logo]()
$212
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:14 am -
1 stop16h 25m
Deal found 8/19![American Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:56 pm -
3 stops46h 25m
Deal found 8/23![Multiple Airlines logo]()
$217
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:59 pm -
1 stop19h 32m
Deal found 8/20![American Airlines logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:20 pm -
1 stop8h 41m
Deal found 8/22![Copa Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am -
3 stops20h 15m
Deal found 8/20![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:26 am -
2 stops24h 55m
Deal found 8/20![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:00 am -
3 stops19h 15m
Deal found 8/21![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:20 pm -
1 stop26h 10m
Deal found 8/23![Copa Airlines logo]()
$233
This Copa Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:01 am -
1 stop9h 29m
Deal found 8/21![Copa Airlines logo]()
$236
Find flight deals from O'Hare Intl to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $469 (Copa Airlines) |
One-way from | $208 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $538 |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 24, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Sat 11/14
2:13 pm-11:55 pm
1 stop8h 42m
Guayaquil Jose Joaquin de Olmedo
Sun 11/29
2:47 pm-12:46 pm
1 stop22h 59m
$469
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Thu 11/26
2:13 pm-11:55 pm
1 stop8h 42m
Guayaquil Jose Joaquin de Olmedo
Wed 12/9
12:22 pm-12:46 pm
1 stop25h 24m
$469
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Sun 11/1
7:35 am-5:35 pm
1 stop9h 00m
Guayaquil Jose Joaquin de Olmedo
Sun 11/8
2:47 pm-12:46 pm
1 stop22h 59m
$493
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Sat 9/19
8:01 am-11:21 am
1 stop27h 20m
Guayaquil Jose Joaquin de Olmedo
Wed 9/23
12:22 pm-1:02 am
1 stop12h 40m
$516
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Sat 10/17
8:01 am-11:37 pm
1 stop15h 36m
Guayaquil Jose Joaquin de Olmedo
Sat 10/24
2:33 pm-12:57 am
1 stop10h 24m
$523
Quickest round-trip
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Sun 10/4
3:20 pm-12:01 am
1 stop8h 41m
Guayaquil Jose Joaquin de Olmedo
Sun 10/11
4:14 am-1:59 pm
1 stop9h 45m
$576
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Wed 9/9
8:01 am-12:01 am
1 stop16h 00m
Guayaquil Jose Joaquin de Olmedo
Wed 9/16
6:00 am-1:02 am
1 stop19h 02m
$638
Cheapest one-way
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Tue 11/17
2:13 pm-1:42 pm
1 stop22h 29m
$212
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Mon 10/19
3:20 pm-10:33 am
1 stop19h 13m
$212
ChicagoGuayaquil
ORD Chicago O'Hare Intl - GYE Guayaquil Jose Joaquin de Olmedo
ORDGYE
Chicago O'Hare Intl
Tue 10/13
10:20 am-10:39 pm
2 stops12h 19m
$215
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from O'Hare Intl to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Guayaquil in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*2 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from O'Hare Intl to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from O'Hare Intl with our price prediction graph.
ORD-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to Guayaquil
Prices
More
How far ahead should I book a flight from Chicago O'Hare Intl Airport to Guayaquil?
To ensure you get the cheapest price possible for a flight from Chicago O'Hare Intl Airport to Guayaquil, you should look to book at least 17 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Guayaquil?
Currently, April is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Guayaquil (average of $352). Flying from Chicago O'Hare Intl Airport to Guayaquil in December is currently the most expensive (average of $654). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Chicago O'Hare Intl Airport to Guayaquil?
Airfare is below average for this route at the moment.
Chicago O'Hare Intl Airport to Guayaquil flights typically cost between $492 and $653 in November.The cheapest round-trip price found within the last 5 days was $469 on Copa Airlines (Nov 14-Nov 29).
What’s the top layover airport for flights from Chicago O'Hare Intl Airport to Guayaquil?
Share of 1-stop round-trip flights from Chicago O'Hare Intl Airport to Guayaquil chosen by Cheapflights users in the past 12 months, using the same layover each way.
Panama City (PTY) – chosen by Cheapflights users on 77% of 1-stop itineraries from Chicago O'Hare Intl Airport to Guayaquil on Cheapflights.
What’s the cheapest layover airport for flights from Chicago O'Hare Intl Airport to Guayaquil?
Average round-trip fare for 1-stop flights from Chicago O'Hare Intl Airport to Guayaquil, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $580.
What’s the fastest layover option from Chicago O'Hare Intl Airport to Guayaquil?
Shortest average travel time for 1-stop one-way flights from Chicago O'Hare Intl Airport to Guayaquil, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 8h 52m.
Which airport typically offers the quickest layover for flights from Chicago O'Hare Intl Airport to Guayaquil?
Average layover duration for 1-stop one-way flights from Chicago O'Hare Intl Airport to Guayaquil, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 50m.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated August 24, 2026.
Read through reviews of airlines operating flights from Chicago O'Hare Intl Airport to Guayaquil, such as Copa Airlines,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.6
Entertainment
6.8
Crew
8.1
Food
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Entertainment
6.8
Crew
8.1
Food
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Entertainment
6.8
Crew
8.1
Food
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Entertainment
6.8
Crew
8.1
Food
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Entertainment
6.8
Crew
8.1
Food
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Entertainment
6.8
Crew
8.1
Food
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
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O'Hare Intl and Guayaquil flights
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Top 5 airlines flying from O'Hare Intl to Guayaquil
Discover the top 5 airlines that operate flights from O'Hare Intl to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$309 | Average$532 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$352 | Average$579 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$369 | Average$540 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$382 | Average$666 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$387 | Average$777 | FlexibilityNo cancel fee | On-time71% |