How popular is this North Carolina to Panama City flight route?

Within the past month, 31 users have taken a look at flights from North Carolina to Panama City Tocumen Intl.

What are the cheapest airlines to fly from North Carolina to Panama City one-way?

For one-way options, check prices for Delta. According to our data, you can fly for as low as $160. Users have also found prices from $208 and $303 on United Airlines and American Airlines, respectively.

What are the most popular routes from North Carolina to Panama City?

Most travelers choose Raleigh-Durham - Panama City Tocumen Intl, Charlotte Douglas - Panama City Tocumen Intl or Norfolk - Panama City Tocumen Intl when deciding on the best route from North Carolina to Panama City.

What are the cheapest flights from North Carolina to Panama City?

Looking for the cheapest flight from North Carolina to Panama City? While on average our users pay $580, our data indicates the cheapest price to be $140. The most popular route (Raleigh-Durham - Panama City Tocumen Intl), is priced around $395.

What are the most popular airlines that fly from North Carolina to Panama City?

Before booking your flight from North Carolina to Panama City check out the most popular airlines for this route: American Airlines, Copa Airlines or Delta.

How far in advance should I book a flight from North Carolina to Panama City?

To save up to 31% on this flight, we recommend booking at least 53 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from North Carolina to Panama City from $513 1-2 weeks out and tickets from $660 for flights departing within the next 72 hours.

What is the cheapest month to fly from North Carolina to Panama City?

Our data shows that September tends to be the cheapest month to fly to Panama City from North Carolina. Users have commonly found prices around $574 for the month, but tickets can be as low as $412. Due to multiple factors, prepare for potentially higher prices in December.

What airport do you fly into for flights to Panama City from North Carolina?

If you book a flight to Panama City from North Carolina, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City.

Can I find deals for flights from North Carolina to Panama City that include hotel bookings?

Yes. In addition to deals on North Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from North Carolina to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama City.

Can I find deals for business class flights from North Carolina to Panama City?

Yes. Cheapflights offers flight deals from North Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$160+ Flights from North Carolina to Panama City

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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheap flight deals from North Carolina to Panama City

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$374 (United Airlines)
One-way from	$160 (Delta)
Popular in	December
Cheapest in	September
Average price	$526
Good round-trip deal	$348 or less
Good one-way deal	$155 or less

Provider with most accurate pricing for Charlotte Douglas-Panama City Tocumen Intl flight deals.

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Provider most trusted by Cheapflights users for Charlotte Douglas-Panama City Tocumen Intl flights.

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From North Carolina to Panama City Tocumen Intl

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One-way flight from North Carolina to Panama City Tocumen Intl

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Highest demand for flights based on searches. 15% potential increase in price ($106 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($28 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in May 2025

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Price to beat on a round-trip flight from North Carolina to Panama City Tocumen Intl.

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Price to beat on a one-way flight from North Carolina to Panama City Tocumen Intl.

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Find flight deals from North Carolina to Panama City

Cheapest flights from North Carolina to Panama City
Explore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2025.

Wed 7/236:00 amORF - PTY

1 stop8h 50mUnited Airlines

Wed 7/307:55 amPTY - ORF

2 stops24h 46mUnited Airlines

Deal found 5/21

$374

Tue 7/15:34 amGSO - PTY

1 stop8h 34mDelta

Tue 7/82:28 pmPTY - GSO

1 stop8h 30mDelta

Deal found 5/20

$385

Tue 8/196:29 amORF - PTY

1 stop8h 51mAmerican Airlines

Fri 8/223:40 pmPTY - ORF

2 stops19h 33mAmerican Airlines

Deal found 5/21

$388

Wed 10/154:19 pmRDU - PTY

Nonstop4h 27mCopa Airlines

Wed 10/228:57 amPTY - RDU

Nonstop4h 31mCopa Airlines

Deal found 5/21

$395

Sun 10/125:20 amRDU - PTY

1 stop8h 27mDelta

Tue 10/212:12 pmPTY - RDU

1 stop21h 37mDelta

Deal found 5/20

$401

Tue 8/196:40 amORF - PTY

1 stop7h 10mDelta

Fri 8/222:05 pmPTY - ORF

1 stop9h 19mDelta

Deal found 5/21

$401

Mon 6/305:45 amAVL - PTY

1 stop8h 23mDelta

Sun 7/68:10 amPTY - AVL

1 stop8h 50mDelta

Deal found 5/21

$404

Tue 6/36:30 amRDU - PTY

1 stop13h 07mUnited Airlines

Fri 6/69:45 amPTY - RDU

1 stop10h 35mUnited Airlines

Deal found 5/20

$409

Sun 6/16:18 pmRDU - PTY

2 stops19h 01mAmerican Airlines

Sun 6/83:20 pmPTY - RDU

2 stops16h 45mAmerican Airlines

Deal found 5/20

$414

Sat 6/711:24 amCLT - PTY

1 stop9h 29mDelta

Sat 6/148:10 amPTY - CLT

1 stop9h 10mDelta

Deal found 5/21

$433

Thu 8/2810:25 pmCLT - PTY

1 stop16h 55mAmerican Airlines

Tue 9/23:40 pmPTY - CLT

1 stop15h 32mAmerican Airlines

Deal found 5/20

$447

Thu 10/96:15 pmGSO - PTY

2 stops19h 10mAmerican Airlines

Wed 10/151:50 pmPTY - GSO

2 stops19h 10mAmerican Airlines

Deal found 5/20

$452

Best flights from North Carolina to Panama City
Discover carefully curated flight deals from North Carolina to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 21, 2025.

Wed 7/236:00 amORF - PTY

1 stop8h 50mUnited Airlines

Wed 7/307:55 amPTY - ORF

2 stops24h 46mUnited Airlines

Deal found 5/21

$374

Tue 7/15:34 amGSO - PTY

1 stop8h 34mDelta

Tue 7/82:28 pmPTY - GSO

1 stop8h 30mDelta

Deal found 5/20

$385

Tue 8/196:29 amORF - PTY

1 stop8h 51mAmerican Airlines

Fri 8/223:40 pmPTY - ORF

2 stops19h 33mAmerican Airlines

Deal found 5/21

$388

Wed 10/154:19 pmRDU - PTY

Nonstop4h 27mCopa Airlines

Wed 10/228:57 amPTY - RDU

Nonstop4h 31mCopa Airlines

Deal found 5/20

$395

Thu 6/56:00 amCLT - PTY

2 stops16h 10mMultiple Airlines

Sun 6/83:20 amPTY - CLT

2 stops13h 19mMultiple Airlines

Deal found 5/20

$501

Sat 6/76:00 amCLT - PTY

2 stops33h 45mAvianca

Sat 6/143:40 pmPTY - CLT

2 stops17h 10mAvianca

Deal found 5/21

$769

Sun 10/126:25 amRDU - PTY

1 stop7h 22mDelta

Mon 10/202:12 pmPTY - RDU

1 stop21h 37mDelta

Deal found 5/20

$401

Tue 6/36:30 amRDU - PTY

1 stop13h 07mUnited Airlines

Fri 6/69:45 amPTY - RDU

1 stop10h 35mUnited Airlines

Deal found 5/20

$409

Sun 6/16:18 pmRDU - PTY

2 stops19h 01mAmerican Airlines

Sun 6/83:20 pmPTY - RDU

2 stops16h 45mAmerican Airlines

Deal found 5/20

$414

Tue 8/196:40 amORF - PTY

1 stop7h 10mDelta

Fri 8/222:05 pmPTY - ORF

1 stop9h 19mDelta

Deal found 5/21

$401

Mon 6/305:45 amAVL - PTY

1 stop8h 23mDelta

Sun 7/68:10 amPTY - AVL

1 stop8h 50mDelta

Deal found 5/21

$404

Thu 8/2810:25 pmCLT - PTY

1 stop16h 55mAmerican Airlines

Tue 9/23:40 pmPTY - CLT

1 stop15h 32mAmerican Airlines

Deal found 5/20

$447

Last-minute flights from North Carolina to Panama City
Discover last-minute flight deals from North Carolina to Panama City. Data last updated May 21, 2025 and is based on user searches.

Mon 5/262:32 pmFAY - PTY

2 stops22h 47mAmerican Airlines

Sun 6/11:20 pmPTY - FAY

2 stops17h 54mAmerican Airlines

Deal found 5/21

$652

Mon 5/266:30 amRDU - PTY

1 stop8h 44mUnited Airlines

Sun 6/13:30 pmPTY - RDU

2 stops21h 40mUnited Airlines

Deal found 5/20

$727

Mon 5/266:00 amFAY - PTY

1 stop7h 48mDelta

Sun 6/18:00 amPTY - FAY

1 stop9h 16mDelta

Deal found 5/20

$1,272

Tue 5/274:48 pmRDU - PTY

2 stops28h 42mMultiple Airlines

Sun 6/18:57 amPTY - RDU

Nonstop4h 32mMultiple Airlines

Deal found 5/21

$1,789

Tue 5/275:40 amILM - PTY

1 stop7h 39mAmerican Airlines

Wed 6/41:20 pmPTY - ILM

1 stop8h 44mAmerican Airlines

Deal found 5/20

$2,914

Tue 5/276:00 amRDU - PTY

2 stops29h 25mAvianca

Mon 6/28:10 pmPTY - RDU

2 stops45h 35mAvianca

Deal found 5/20

$2,968

Wed 5/289:00 amRDU - PTY

2 stops28h 19mAmerican Airlines

Fri 5/301:20 pmPTY - RDU

1 stop6h 55mAmerican Airlines

Deal found 5/21

$1,190

Wed 5/284:19 pmRDU - PTY

Nonstop4h 27mCopa Airlines

Fri 5/308:57 amPTY - RDU

Nonstop4h 32mCopa Airlines

Deal found 5/21

$1,712

Sun 6/16:18 pmRDU - PTY

2 stops19h 01mAmerican Airlines

Sun 6/83:20 pmPTY - RDU

2 stops16h 45mAmerican Airlines

Deal found 5/20

$414

Mon 6/24:20 pmRDU - PTY

Nonstop4h 26mCopa Airlines

Fri 6/68:57 amPTY - RDU

Nonstop4h 32mCopa Airlines

Deal found 5/20

$395

Tue 6/36:30 amRDU - PTY

1 stop10h 42mUnited Airlines

Mon 6/910:00 amPTY - RDU

1 stop10h 55mUnited Airlines

Deal found 5/21

$409

Tue 6/36:00 amGSO - PTY

1 stop8h 50mUnited Airlines

Tue 6/1010:55 pmPTY - GSO

1 stop10h 58mUnited Airlines

Deal found 5/20

$495

One-way flights from North Carolina to Panama City
Search for one-way flight options from North Carolina to Panama City. Find affordable one-way fares based on user searches. Data last updated May 21, 2025.

Tue 10/285:45 amAVL - PTY

1 stop8h 02mDelta

Deal found 5/20

$160

Tue 10/285:35 pmAVL - PTY

2 stops26h 27mUnited Airlines

Deal found 5/20

$208

Wed 6/116:00 amGSO - PTY

1 stop8h 50mUnited Airlines

Deal found 5/20

$215

Sun 7/205:36 amCLT - PTY

1 stop8h 37mDelta

Deal found 5/20

$231

Tue 6/311:23 amCLT - PTY

2 stops30h 53mMultiple Airlines

Deal found 5/20

$241

Sat 11/1510:41 amRDU - PTY

2 stops21h 32mMultiple Airlines

Deal found 5/20

$248

Fri 7/46:49 amRDU - PTY

1 stop12h 48mUnited Airlines

Deal found 5/20

$295

Mon 5/267:00 amCLT - PTY

1 stop8h 14mUnited Airlines

Deal found 5/21

$301

Sun 5/2512:00 pmTYS - PTY

1 stop29h 12mUnited Airlines

Deal found 5/20

$302

Sat 11/157:36 pmRDU - PTY

1 stop19h 44mAmerican Airlines

Deal found 5/20

$303

Sun 5/254:10 pmTYS - PTY

2 stops21h 09mAmerican Airlines

Deal found 5/20

$321

Mon 5/265:15 pmCLT - PTY

2 stops20h 04mAmerican Airlines

Deal found 5/21

$346

Cheapflights Fare Finder

Use the filters below to find and compare flights from North Carolina to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 7/23

6:00 am-1:50 pm

1 stop8h 50m

Panama City Tocumen Intl

Wed 7/30

7:55 am-9:41 am

2 stops24h 46m

$374

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

Tue 7/1

5:34 am-1:08 pm

1 stop8h 34m

Panama City Tocumen Intl

Tue 7/8

2:28 pm-11:58 pm

1 stop8h 30m

$385

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Tue 8/19

6:29 am-2:20 pm

1 stop8h 51m

Panama City Tocumen Intl

Fri 8/22

3:40 pm-12:13 pm

2 stops19h 33m

$388

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 10/15

4:19 pm-7:46 pm

Nonstop4h 27m

Panama City Tocumen Intl

Wed 10/22

8:57 am-2:28 pm

Nonstop4h 31m

$395

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 10/12

6:25 am-12:47 pm

1 stop7h 22m

Panama City Tocumen Intl

Mon 10/20

2:12 pm-12:49 pm

1 stop21h 37m

$401

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Tue 8/19

6:40 am-12:50 pm

1 stop7h 10m

Panama City Tocumen Intl

Fri 8/22

2:05 pm-12:24 am

1 stop9h 19m

$401

AshevillePanama City

AVL - PTY

AVLPTY

Asheville Regional

Mon 6/30

5:45 am-1:08 pm

1 stop8h 23m

Panama City Tocumen Intl

Sun 7/6

8:10 am-6:00 pm

1 stop8h 50m

$404

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Tue 6/3

6:30 am-6:37 pm

1 stop13h 07m

Panama City Tocumen Intl

Fri 6/6

9:45 am-9:20 pm

1 stop10h 35m

$409

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 6/1

6:18 pm-12:19 pm

2 stops19h 01m

Panama City Tocumen Intl

Sun 6/8

3:20 pm-9:05 am

2 stops16h 45m

$414

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 6/7

11:24 am-7:53 pm

1 stop9h 29m

Panama City Tocumen Intl

Sat 6/14

8:10 am-6:20 pm

1 stop9h 10m

$433

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/20

Showing 1-10 of 48 results

...

Best time to book a flight from North Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from North Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama City

What is the cheapest month to book a flight from North Carolina to Panama City?

Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama City (average of $478). Flying from North Carolina to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to PTY?

When flying from North Carolina to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama City by month

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Temperature in Panama City by month

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama City

Peruse reviews from past customers who have flown with Delta, Copa Airlines and United Airlines from North Carolina to Panama City to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,951 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,951 reviews

Delta

8.0

Very good

7,951 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Copa Airlines

7.5

Good

1,428 reviews

Delta

8.0

Very good

7,951 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,745 reviews

Delta

8.0

Very good

7,951 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,951 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Avianca

6.7

Okay

2,329 reviews

Delta

8.0

Very good

7,951 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly into for flights to Panama City from North Carolina?
If you book a flight to Panama City from North Carolina, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City.
How popular is this North Carolina to Panama City flight route?
Within the past month, 31 users have taken a look at flights from North Carolina to Panama City Tocumen Intl.
What are the cheapest airlines to fly from North Carolina to Panama City one-way?
For one-way options, check prices for Delta. According to our data, you can fly for as low as $160. Users have also found prices from $208 and $303 on United Airlines and American Airlines, respectively.
What are the most popular routes from North Carolina to Panama City?
Most travelers choose Raleigh-Durham - Panama City Tocumen Intl, Charlotte Douglas - Panama City Tocumen Intl or Norfolk - Panama City Tocumen Intl when deciding on the best route from North Carolina to Panama City.
What are the cheapest flights from North Carolina to Panama City?
Looking for the cheapest flight from North Carolina to Panama City? While on average our users pay $580, our data indicates the cheapest price to be $140. The most popular route (Raleigh-Durham - Panama City Tocumen Intl), is priced around $395.
Can I find deals for flights from North Carolina to Panama City that include hotel bookings?
Yes. In addition to deals on North Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from North Carolina to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama City.
Can I find deals for business class flights from North Carolina to Panama City?
Yes. Cheapflights offers flight deals from North Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from North Carolina to Panama City?
Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama City (average of $478). Flying from North Carolina to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from North Carolina to Panama City

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$249	Average$587	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$282	Average$408	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$302	Average$557	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$412	Average$505	FlexibilityNo cancel fee	On-time69%

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$160+ Cheap flights from North Carolina to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from North Carolina to Panama City with Cheapflights

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Cheap flight deals from North Carolina to Panama City

Keep the following information in mind while searching for North Carolina to Panama City flight deals. Data was last updated May 21, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from North Carolina to Panama City

Cheapest flights from North Carolina to Panama CityExplore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2025.

Explore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from North Carolina to Panama City that are best for you.

Best time to book a flight from North Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from North Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama City

What is the cheapest month to book a flight from North Carolina to Panama City?

What is the cheapest time of day to fly from NC to PTY?

Find hourly flight availability from North Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 21, 2025.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

Reviews of airlines servicing Panama City

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Panama City from North Carolina?

How popular is this North Carolina to Panama City flight route?

What are the cheapest airlines to fly from North Carolina to Panama City one-way?

What are the most popular routes from North Carolina to Panama City?

What are the cheapest flights from North Carolina to Panama City?

Can I find deals for flights from North Carolina to Panama City that include hotel bookings?

How can I find direct flights from North Carolina to Panama City?

Can I find deals for business class flights from North Carolina to Panama City?

What is the cheapest month to book a flight from North Carolina to Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for North Carolina to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from North Carolina to Panama City

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Cheapest flights from North Carolina to Panama City
Explore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2025.