HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$215+ Cheap flights from North Carolina to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
Jun 26 — Jul 31
Fri 6/26
Fri 7/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from North Carolina to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from North Carolina to Panama

Cheapest flights from North Carolina to Panama
Explore the most affordable flight options available from North Carolina to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 27, 2026.

This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:23 am
ORF
-
PTY
1 stop8h 32m
Delta
Wed 8/262:20 pm
PTY
-
ORF
1 stop9h 43m
Delta
Deal found 5/27$497
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:10 am
ORF
-
PTY
1 stop9h 04m
United Airlines
Wed 8/2610:55 pm
PTY
-
ORF
2 stops21h 46m
United Airlines
Deal found 5/27$501
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:29 am
ORF
-
PTY
1 stop8h 33m
United Airlines
Mon 11/1610:00 am
PTY
-
ORF
1 stop24h 10m
United Airlines
Deal found 5/27$504
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:48 pm
CLT
-
PTY
1 stop14h 18m
Multiple Airlines
Fri 7/245:30 am
PTY
-
CLT
2 stops10h 42m
Multiple Airlines
Deal found 5/25$508
This American Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:59 pm
ORF
-
PTY
1 stop20h 16m
American Airlines
Tue 10/63:35 pm
PTY
-
ORF
2 stops21h 38m
American Airlines
Deal found 5/26$512
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:48 pm
CLT
-
PTY
1 stop14h 42m
Multiple Airlines
Tue 7/283:10 pm
PTY
-
CLT
2 stops25h 02m
Multiple Airlines
Deal found 5/25$516
This Kiwi.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:48 pm
CLT
-
PTY
1 stop14h 42m
Multiple Airlines
Thu 7/235:30 am
PTY
-
CLT
2 stops10h 42m
Multiple Airlines
Deal found 5/27$518
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:45 am
CLT
-
PTY
1 stop7h 11m
Delta
Wed 11/43:21 pm
PTY
-
CLT
1 stop8h 32m
Delta
Deal found 5/25$519
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/42:35 pm
CLT
-
PTY
1 stop14h 29m
United Airlines
Tue 8/113:30 pm
PTY
-
CLT
2 stops17h 38m
United Airlines
Deal found 5/26$523
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:09 am
CLT
-
PTY
1 stop12h 28m
United Airlines
Mon 7/2010:55 pm
PTY
-
CLT
1 stop20h 58m
United Airlines
Deal found 5/26$527
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:35 pm
CLT
-
PTY
1 stop14h 49m
American Airlines
Tue 8/251:24 pm
PTY
-
CLT
1 stop18h 01m
American Airlines
Deal found 5/22$529
This American Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:13 am
ORF
-
PTY
1 stop8h 26m
American Airlines
Mon 8/311:39 pm
PTY
-
ORF
1 stop8h 54m
American Airlines
Deal found 5/26$531

Find flight deals from North Carolina to Panama

Keep the following information in mind while searching for North Carolina to Panama flight deals. Data was last updated May 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$497
(Delta)

One-way from

$215
(KAYAK)

Popular in

December

Cheapest in

September

Average price

$609

Good round-trip deal

$397 or less

Good one-way deal

$281 or less
Provider with most accurate pricing for Raleigh-Durham-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Panama City Tocumen Intl flights.
Search Deals
From North Carolina to Panama
Search Deals
One-way flight from North Carolina to Panama
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($79 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals
Price to beat on a round-trip flight from North Carolina to Panama.
Search Deals
Price to beat on a one-way flight from North Carolina to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 27, 2026.
Use the filters below to find and compare flights from North Carolina to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 8/12

5:23 am-12:55 pm

1 stop8h 32m

Panama City Tocumen Intl

Wed 8/26

2:20 pm-1:03 am

1 stop9h 43m

$497

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 11/12

11:29 am-8:02 pm

1 stop8h 33m

Panama City Tocumen Intl

Mon 11/16

10:00 am-11:36 pm

2 stops13h 36m

$497

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 10/1

5:40 pm-12:15 pm

2 stops19h 35m

Panama City Tocumen Intl

Tue 10/6

3:35 pm-12:14 pm

2 stops19h 39m

$501

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 10/15

5:30 am-12:56 pm

1 stop8h 26m

Panama City Tocumen Intl

Thu 10/22

2:21 pm-11:53 pm

1 stop8h 32m

$519

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 10/21

5:30 am-12:56 pm

1 stop8h 26m

Panama City Tocumen Intl

Wed 11/4

3:21 pm-11:53 pm

1 stop8h 32m

$519

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 8/20

10:25 am-4:04 am

2 stops18h 39m

Panama City Tocumen Intl

Tue 8/25

3:30 pm-10:08 am

2 stops17h 38m

$523

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 8/31

7:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Thu 9/3

10:00 am-10:08 am

2 stops23h 08m

$523

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 8/24

5:36 pm-7:31 pm

2 stops26h 55m

Panama City Tocumen Intl

Thu 8/27

3:30 pm-10:08 am

2 stops17h 38m

$523

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 8/4

8:05 am-4:04 am

2 stops20h 59m

Panama City Tocumen Intl

Tue 8/11

3:30 pm-9:46 pm

2 stops29h 16m

$523

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 8/3

7:09 am-4:12 pm

1 stop10h 03m

Panama City Tocumen Intl

Tue 8/11

3:30 pm-10:08 am

2 stops17h 38m

$523

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/26

Showing 1-10 of 59 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from North Carolina to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama

What is the cheapest month to book a flight from North Carolina to Panama?

Currently, August is the cheapest month in which you can book a flight from North Carolina to Panama (average of $184). Flying from North Carolina to Panama in May is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to PA?

Find hourly flight availability from North Carolina to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 27, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from North Carolina to Panama as you normally would.

How far ahead should I book a flight from North Carolina to Panama?

Booking 67 days in advance of your planned departure date is, on average, the best time to get cheap flights from North Carolina to Panama. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from North Carolina to Panama?

    There are many flights that can get you from North Carolina to Panama in 8h 32m. Fly via Delta, United Airlines, or American Airlines to get the fastest option. The distance from North Carolina to Panama is about 1931 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from North Carolina to Panama one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $191. Users have also found prices from $199 and $588 on American Airlines and Copa Airlines, respectively.

  • Can I find deals for flights from North Carolina to Panama that include hotel bookings?

    Yes. In addition to deals on North Carolina to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama.

  • Can I find deals for business class flights from North Carolina to Panama?

    Yes. Cheapflights offers flight deals from North Carolina to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Panama?

    Currently, August is the cheapest month in which you can book a flight from North Carolina to Panama (average of $184). Flying from North Carolina to Panama in May is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for North Carolina to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to San Salvador flights
John F Kennedy Intl to Panama City flights
Dulles Intl to San Salvador flights
Newark to San José flights
John F Kennedy Intl to San José flights
Los Angeles to Guatemala City flights
Hobby to San Salvador flights
John F Kennedy Intl to San Salvador flights
Newark to Guatemala City flights
George Bush Intcntl to San Salvador flights
Miami to Panama City flights
Dallas/Fort Worth to San Salvador flights
Miami to Managua flights
Dulles Intl to Panama City flights
Miami to San José flights
Fort Lauderdale to San José flights
Reagan-National to San Salvador flights
Miami to San Salvador flights
Newark to Panama City flights
Los Angeles to San José flights
Baltimore to San Salvador flights
Newark to San Salvador flights
LaGuardia to San José flights
Dulles Intl to Guatemala City flights
LaGuardia to Guatemala City flights
LaGuardia to San Salvador flights
Atlanta to San José flights
John F Kennedy Intl to Liberia flights
George Bush Intcntl to San Pedro Sula flights
Dulles Intl to San José flights
Ontario to San Salvador flights
Atlanta to Panama City flights
John F Kennedy Intl to Guatemala City flights
Miami to Guatemala City flights
Hobby to San José flights
Dallas/Fort Worth to San José flights
Los Angeles to Panama City flights
Orlando to San José flights
Los Angeles to Liberia flights
George Bush Intcntl to Guatemala City flights
Baltimore to Panama City flights
San Francisco to San José flights
Newark to Liberia flights
Baltimore to San José flights
John F Kennedy Intl to Philip S.W.Goldson flights
Fort Lauderdale to Panama City flights
Dallas/Fort Worth to Panama City flights

Top 4 airlines flying from North Carolina to Panama

Discover the top 4 airlines that operate flights from North Carolina to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$184Average$709FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$352Average$637FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$416Average$610FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$418Average$552FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.