$255+ Cheap flights from North Carolina to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
Nov 18 — Nov 251
Round-trip
1 adult, Economy
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Find cheap flights from North Carolina to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from North Carolina to PanamaExplore the most affordable flight options available from North Carolina to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from North Carolina to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:00 am -
1 stop9h 13m
Sat 11/213:34 pm -
1 stop16h 41m
Deal found 10/16![American Airlines logo]()
$575
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:25 pm -
1 stop22h 09m
Sat 12/53:13 pm -
1 stop8h 57m
Deal found 10/16![American Airlines logo]()
$586
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:30 am -
1 stop8h 32m
Mon 11/233:29 pm -
1 stop17h 13m
Deal found 10/15![Delta logo]()
$615
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:30 am -
1 stop8h 32m
Sun 11/223:29 pm -
1 stop24h 40m
Deal found 10/15![Delta logo]()
$622
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:25 pm -
1 stop16h 09m
Tue 12/13:34 pm -
1 stop8h 32m
Deal found 10/16![American Airlines logo]()
$625
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:06 am -
1 stop10h 13m
Fri 11/2012:03 pm -
1 stop8h 27m
Deal found 10/14![Multiple Airlines logo]()
$660
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:50 pm -
1 stop12h 34m
Wed 11/49:31 pm -
1 stop20h 52m
Deal found 10/15![Multiple Airlines logo]()
$663
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/298:00 am -
1 stop13h 45m
Thu 1/78:00 am -
1 stop9h 17m
Deal found 10/18![Delta logo]()
$664
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:32 pm -
2 stops26h 30m
Wed 12/910:00 am -
1 stop13h 13m
Deal found 10/19![United Airlines logo]()
$686
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/3111:03 am -
1 stop10h 42m
Fri 1/88:00 am -
1 stop11h 02m
Deal found 10/18![Delta logo]()
$689
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/212:58 pm -
2 stops18h 31m
Wed 11/186:15 pm -
1 stop24h 08m
Deal found 10/17![Multiple Airlines logo]()
$693
This Copa Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:17 pm -
Nonstop4h 29m
Mon 11/238:57 am -
Nonstop4h 30m
Deal found 10/15![Copa Airlines logo]()
$697
Best flights from North Carolina to PanamaDiscover carefully curated flight deals from North Carolina to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from North Carolina to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/710:25 am -
1 stop9h 37m
Mon 1/184:41 pm -
1 stop29h 27m
Deal found 10/19![United Airlines logo]()
$641
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:00 am -
1 stop6h 26m
Tue 1/262:26 pm -
1 stop8h 12m
Deal found 10/15![American Airlines logo]()
$646
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/298:00 am -
1 stop13h 45m
Thu 1/78:00 am -
1 stop9h 17m
Deal found 10/18![Delta logo]()
$664
This Copa Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/43:13 pm -
Nonstop4h 33m
Mon 12/148:57 am -
Nonstop4h 24m
Deal found 10/18![Copa Airlines logo]()
$717
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:00 am -
1 stop14h 02m
Mon 1/2510:00 am -
1 stop11h 59m
Deal found 10/18![United Airlines logo]()
$649
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/57:00 am -
1 stop8h 55m
Sun 2/142:47 pm -
1 stop9h 03m
Deal found 10/17![American Airlines logo]()
$699
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
1 stop7h 59m
Mon 2/83:20 pm -
1 stop8h 34m
Deal found 10/18![Delta logo]()
$700
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:40 pm -
2 stops19h 05m
Wed 2/311:35 am -
2 stops22h 55m
Deal found 10/17![United Airlines logo]()
$654
This Copa Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:19 pm -
Nonstop4h 27m
Mon 11/28:57 am -
Nonstop4h 30m
Deal found 10/15![Copa Airlines logo]()
$792
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/27:10 am -
1 stop14h 35m
Thu 1/143:20 pm -
1 stop8h 34m
Deal found 10/19![Delta logo]()
$738
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2311:10 am -
1 stop8h 52m
Thu 3/410:00 am -
1 stop13h 51m
Deal found 10/19![United Airlines logo]()
$685
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/136:02 pm -
2 stops21h 28m
Sat 2/204:31 pm -
1 stop7h 22m
Deal found 10/17![American Airlines logo]()
$786
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:40 am -
1 stop6h 19m
Sun 11/153:29 pm -
1 stop8h 28m
Deal found 10/17![Delta logo]()
$738
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:32 pm -
2 stops26h 30m
Wed 12/910:00 am -
1 stop13h 13m
Deal found 10/19![United Airlines logo]()
$686
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:00 am -
1 stop8h 34m
Sun 12/63:13 pm -
2 stops19h 36m
Deal found 10/15![American Airlines logo]()
$802
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop8h 02m
Sat 12/53:29 pm -
1 stop8h 27m
Deal found 10/17![Delta logo]()
$738
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:32 pm -
2 stops26h 06m
Mon 12/1410:00 am -
1 stop13h 13m
Deal found 10/17![United Airlines logo]()
$686
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:25 am -
1 stop8h 34m
Tue 2/93:20 pm -
1 stop8h 34m
Deal found 10/18![Delta logo]()
$739
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:13 pm -
1 stop20h 00m
Wed 11/113:13 pm -
2 stops22h 28m
Deal found 10/17![American Airlines logo]()
$817
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:55 am -
1 stop9h 07m
Wed 12/98:55 am -
2 stops15h 04m
Deal found 10/17![United Airlines logo]()
$714
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
1 stop6h 59m
Mon 2/83:20 pm -
1 stop8h 34m
Deal found 10/16![Delta logo]()
$745
This BusinessClass deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/46:10 am -
2 stops9h 59m
Sun 2/149:47 am -
2 stops33h 11m
Deal found 10/16![Copa Airlines logo]()
$1,118
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:49 pm -
2 stops21h 45m
Sun 12/63:13 pm -
2 stops18h 34m
Deal found 10/15![American Airlines logo]()
$842
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:15 am -
2 stops13h 23m
Mon 2/810:00 am -
2 stops25h 08m
Deal found 10/18![United Airlines logo]()
$716
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am -
1 stop7h 59m
Sat 1/98:00 am -
1 stop6h 54m
Deal found 10/18![Delta logo]()
$757
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:39 pm -
2 stops25h 59m
Tue 12/811:35 am -
2 stops22h 25m
Deal found 10/17![United Airlines logo]()
$720
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop8h 02m
Mon 11/233:29 pm -
1 stop7h 42m
Deal found 10/15![Delta logo]()
$779
This Copa Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:00 am -
2 stops25h 45m
Sun 12/68:02 pm -
2 stops38h 20m
Deal found 10/15![Copa Airlines logo]()
$1,289
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:40 pm -
2 stops21h 05m
Tue 11/244:41 pm -
2 stops31h 03m
Deal found 10/19![United Airlines logo]()
$732
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop14h 02m
Fri 11/204:41 pm -
2 stops21h 03m
Deal found 10/17![United Airlines logo]()
$732
Last-minute flights from North Carolina to PanamaDiscover last-minute flight deals from North Carolina to Panama. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to Panama. Data last updated October 19, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:50 pm -
1 stop12h 34m
Wed 11/49:31 pm -
1 stop20h 52m
Deal found 10/15![Multiple Airlines logo]()
$663
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/212:58 pm -
2 stops18h 31m
Wed 11/186:15 pm -
1 stop24h 08m
Deal found 10/17![Multiple Airlines logo]()
$693
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
1 stop7h 59m
Mon 2/83:20 pm -
1 stop8h 34m
Deal found 10/18![Delta logo]()
$700
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:50 pm -
1 stop12h 34m
Fri 11/69:31 pm -
2 stops18h 48m
Deal found 10/14![Multiple Airlines logo]()
$709
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:06 am -
1 stop10h 13m
Fri 11/2012:03 pm -
1 stop8h 27m
Deal found 10/14![Multiple Airlines logo]()
$660
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:00 am -
1 stop9h 13m
Sat 11/213:34 pm -
1 stop16h 41m
Deal found 10/16![American Airlines logo]()
$575
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:30 am -
1 stop8h 32m
Mon 11/233:29 pm -
1 stop17h 13m
Deal found 10/15![Delta logo]()
$615
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:30 am -
1 stop8h 32m
Wed 11/253:29 pm -
1 stop24h 40m
Deal found 10/15![Delta logo]()
$622
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:15 am -
2 stops13h 47m
Wed 11/254:41 pm -
2 stops21h 21m
Deal found 10/15![United Airlines logo]()
$702
This Copa Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:17 pm -
Nonstop4h 29m
Mon 11/238:57 am -
Nonstop4h 30m
Deal found 10/15![Copa Airlines logo]()
$697
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:25 pm -
1 stop22h 09m
Sat 12/53:13 pm -
1 stop8h 57m
Deal found 10/16![American Airlines logo]()
$586
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:25 pm -
1 stop16h 09m
Tue 12/13:34 pm -
1 stop8h 32m
Deal found 10/16![American Airlines logo]()
$625
One-way flights from North Carolina to PanamaSearch for one-way flight options from North Carolina to Panama. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
Search for one-way flight options from North Carolina to Panama. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/16:45 am -
1 stop7h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Delta logo]()
$255
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:20 pm -
1 stop25h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Delta logo]()
$268
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/47:02 am -
1 stop8h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![American Airlines logo]()
$275
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:48 pm -
1 stop20h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![American Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:50 pm -
1 stop18h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![American Airlines logo]()
$281
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:36 am -
1 stop6h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Delta logo]()
$286
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/208:00 am -
2 stops12h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![United Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/277:59 pm -
1 stop25h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Delta logo]()
$301
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/284:45 pm -
1 stop24h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![United Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:06 am -
2 stops34h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Multiple Airlines logo]()
$331
This Avianca deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:52 am -
2 stops14h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:00 am -
1 stop10h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$345
Find flight deals from North Carolina to Panama
Keep the following information in mind while searching for North Carolina to Panama flight deals. Data was last updated October 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $575 (American Airlines) |
One-way from | $255 (Delta) |
Popular in | June |
Cheapest in | April |
Average price | $698 |
Good round-trip deal | $445 or less |
Good one-way deal | $266 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from North Carolina to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Mon 2/1
6:45 am-1:55 pm
1 stop7h 10m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$255
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Mon 11/9
5:30 am-2:02 pm
1 stop8h 32m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$255
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Thu 2/4
7:02 am-3:55 pm
1 stop8h 53m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$275
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Sat 10/24
7:36 am-12:59 pm
1 stop6h 23m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$286
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Mon 2/1
8:00 am-8:02 pm
2 stops12h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$292
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Thu 2/4
8:00 am-8:02 pm
2 stops12h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$292
CharlottePanama City
CLT Charlotte Douglas - PTY Panama City Tocumen Intl
CLTPTY
Charlotte Douglas
Wed 1/20
8:00 am-8:02 pm
2 stops12h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$292
GreensboroPanama City
GSO Greensboro/H. Point - PTY Panama City Tocumen Intl
GSOPTY
Greensboro/H. Point
Wed 12/30
4:58 pm-9:45 pm
1 stop28h 47m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$301
GreensboroPanama City
GSO Greensboro/H. Point - PTY Panama City Tocumen Intl
GSOPTY
Greensboro/H. Point
Tue 12/29
7:59 pm-9:45 pm
1 stop25h 46m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$301
RaleighPanama City
RDU Raleigh-Durham - PTY Panama City Tocumen Intl
RDUPTY
Raleigh-Durham
Mon 11/9
7:43 pm-8:13 pm
3 stops24h 30m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$362
Showing 1-10 of 53 resultsSorted by cheapest first
Best time to book a flight from North Carolina to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from North Carolina with our price prediction graph.
CLT-PTY
GSO-PTY
RDU-PTY
AVL-PTY
FAY-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to Panama
USNC-PA0
CLT-PTY
GSO-PTY
RDU-PTY
AVL-PTY
What is the cheapest month to book a flight from North Carolina to Panama?
Currently, April is the cheapest month in which you can book a flight from North Carolina to Panama (average of $539). Flying from North Carolina to Panama in December is currently the most expensive (average of $809). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from NC to PA?
Find hourly flight availability from North Carolina to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 19, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from North Carolina to Panama as you normally would.
How far ahead should I book a flight from North Carolina to Panama?
Booking 68 days in advance of your planned departure date is, on average, the best time to get cheap flights from North Carolina to Panama. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from North Carolina to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for North Carolina to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from North Carolina to Panama by cabin class
Find flights from North Carolina to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
North Carolina and Panama flights
Browse other North Carolina and Panama flight options. Last updated on October 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Panama
Find the right flight back to North Carolina after your stay in Panama
North Carolina to Panama flights
Consider these flights traveling from North Carolina to Panama.
Top 4 airlines flying from North Carolina to Panama
Discover the top 4 airlines that operate flights from North Carolina to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$286 | Average$760 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$441 | Average$587 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$455 | Average$617 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$455 | Average$685 | FlexibilityNo cancel fee | On-time71% |