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$72+ Cheap flights from South Carolina to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
dec. 21 — dec. 281
søn. 12/21
søn. 12/28
1 adult, Economy
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Find flight deals from South Carolina to Iowa

Cheapest flights from South Carolina to Iowa
Explore the most affordable flight options available from South Carolina to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on november 21, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tor. 12/42:58 pmCLT - CID
1 stop27h 09mMultiple Airlines
man. 12/85:57 pmCID - CLT
1 stop19h 06mMultiple Airlines
Deal found 11/18$195
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
søn. 12/219:38 pmCLT - CID
1 stop21h 31mMultiple Airlines
man. 1/56:44 pmCID - CLT
1 stop24h 49mMultiple Airlines
Deal found 11/20$232
This Frontier deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tor. 12/1812:17 pmCLT - OMA
1 stop8h 30mFrontier
man. 1/511:11 amOMA - CLT
1 stop8h 47mFrontier
Deal found 11/19$248
This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
man. 12/224:55 pmSAV - CID
1 stop5h 39mUnited Airlines
man. 1/58:00 amCID - SAV
1 stop5h 29mUnited Airlines
Deal found 11/18$249
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
man. 12/228:54 amCLT - CID
1 stop10h 15mMultiple Airlines
man. 1/56:44 pmCID - CLT
2 stops20h 58mMultiple Airlines
Deal found 11/19$256
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
man. 12/229:43 pmCLT - MLI
1 stop11h 11mMultiple Airlines
tir. 1/611:39 amMLI - CLT
1 stop26h 58mMultiple Airlines
Deal found 11/19$260
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tir. 12/237:46 pmCLT - CID
2 stops24h 07mMultiple Airlines
man. 1/56:44 pmCID - CLT
1 stop13h 55mMultiple Airlines
Deal found 11/19$266
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lør. 12/209:02 pmCLT - MLI
1 stop13h 22mMultiple Airlines
tir. 1/611:39 amMLI - CLT
1 stop26h 58mMultiple Airlines
Deal found 11/19$267
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fre. 12/199:00 amCLT - CID
1 stop9h 54mMultiple Airlines
man. 1/56:44 pmCID - CLT
1 stop24h 49mMultiple Airlines
Deal found 11/20$273
This Frontier deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
søn. 12/2112:17 pmCLT - OMA
1 stop8h 57mFrontier
man. 1/511:11 amOMA - CLT
1 stop8h 47mFrontier
Deal found 11/19$273
This Frontier deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
man. 12/2212:17 pmCLT - DSM
1 stop8h 27mFrontier
søn. 1/410:17 amDSM - CLT
1 stop9h 21mFrontier
Deal found 11/19$276
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
tor. 12/1110:33 pmCLT - OMA
1 stop21h 11mMultiple Airlines
man. 12/157:34 pmOMA - CLT
1 stop13h 16mMultiple Airlines
Deal found 11/20$276

Cheap flight deals from South Carolina to Iowa

Keep the following information in mind while searching for South Carolina to Iowa flight deals. Data was last updated november 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$195
(Kiwi.com)

One-way from

$72
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Des Moines flights.
Search Deals
From South Carolina to Iowa
Search Deals
One-way flight from South Carolina to Iowa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated november 21, 2025.
Use the filters below to find and compare flights from South Carolina to Iowa that are best for you.

Fly from

South Carolina

Fly to

Iowa

Route

Depart

Return

Price

CharlotteCedar Rapids

CLT - CID

CLTCID

Charlotte Douglas

tor. 12/4

2:58 pm-5:07 pm

1 stop27h 09m

Cedar Rapids

man. 12/8

5:57 pm-2:03 pm

1 stop19h 06m

$195

SavannahCedar Rapids

SAV - CID

SAVCID

Savannah/Hilton Head

lør. 1/24

6:50 am-2:12 pm

2 stops8h 22m

Cedar Rapids

ons. 1/28

5:35 am-11:29 am

1 stop4h 54m

$239

SavannahCedar Rapids

SAV - CID

SAVCID

Savannah/Hilton Head

man. 12/22

4:55 pm-9:34 pm

1 stop5h 39m

Cedar Rapids

man. 1/5

8:00 am-2:29 pm

1 stop5h 29m

$249

SavannahCedar Rapids

SAV - CID

SAVCID

Savannah/Hilton Head

ons. 4/1

3:50 pm-9:54 pm

1 stop7h 04m

Cedar Rapids

lør. 4/4

5:30 am-11:20 am

1 stop4h 50m

$264

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

tor. 12/4

10:20 am-2:20 pm

1 stop5h 00m

Des Moines

man. 12/8

3:17 pm-10:07 pm

1 stop5h 50m

$279

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

tor. 12/4

6:38 am-10:38 am

1 stop5h 00m

Des Moines

søn. 12/7

5:34 am-12:08 pm

1 stop5h 34m

$279

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

tor. 12/4

12:53 pm-8:46 pm

2 stops8h 53m

Des Moines

tir. 12/9

5:34 am-12:08 pm

1 stop5h 34m

$284

ColumbiaMoline

CAE - MLI

CAEMLI

Columbia Metropolitan

lør. 1/24

10:15 am-4:26 pm

1 stop7h 11m

Moline Quad-City

ons. 1/28

5:51 am-11:58 am

1 stop5h 07m

$294

CharlotteMoline

CLT - MLI

CLTMLI

Charlotte Douglas

lør. 12/20

10:38 pm-5:23 pm

2 stops19h 45m

Moline Quad-City

tir. 1/6

11:39 am-3:37 pm

1 stop26h 58m

$297

Myrtle BeachOmaha

MYR - OMA

MYROMA

Myrtle Beach Intl

tor. 1/8

10:18 am-2:14 pm

1 stop4h 56m

Omaha Eppley Airfield

tir. 1/13

3:07 pm-8:54 pm

1 stop4h 47m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Iowa

What is the cheapest month to book a flight from South Carolina to Iowa?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $162). Flying from South Carolina to Iowa in February is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IA?

Find hourly flight availability from South Carolina to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated november 21, 2025.

When flying from South Carolina to Iowa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 27% versus a flight in the morning.

What is the cheapest day to fly from South Carolina to Iowa?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Iowa. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Iowa flight should consider departing on Saturday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated november 21, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from South Carolina to Iowa have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,029 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Iowa?

    Airlines like Delta, United Airlines, and American Airlines fly from South Carolina to Iowa in about 4h 56m. The time it takes to get you to your destination can typically vary by up to 3h 26m. South Carolina and Iowa are separated by a distance of 1066 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Iowa one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $72. American Airlines flights start at $153 while deals on Allegiant Air start at $167 one-way.

  • Can I find deals for flights from South Carolina to Iowa that include hotel bookings?

    Yes. In addition to deals on South Carolina to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Iowa.

  • Can I find deals for business class flights from South Carolina to Iowa?

    Yes. Cheapflights offers flight deals from South Carolina to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Iowa?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $162). Flying from South Carolina to Iowa in February is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Iowa

Discover the top 3 airlines that operate flights from South Carolina to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated november 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$354FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$399FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$452FlexibilityNo cancel feeOn-time69%

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