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$112+ Cheap flights from South Carolina to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Find cheap flights from South Carolina to Iowa with Cheapflights

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Cheap flight deals from South Carolina to Iowa

Keep the following information in mind while searching for South Carolina to Iowa flight deals. Data was last updated September 17, 2025.

Round-trip from

$164
(Booking.com)

One-way from

$112
(Kiwi.com)
From South Carolina to Iowa
Search Deals
One-way flight from South Carolina to Iowa
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Find flight deals from South Carolina to Iowa

Cheapest flights from South Carolina to Iowa
Explore the most affordable flight options available from South Carolina to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:00 pmCLT - OMA
1 stop16h 48mFrontier
Sat 10/258:59 pmOMA - CLT
1 stop18h 40mFrontier
Deal found 9/16$164
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:00 pmCLT - OMA
1 stop16h 48mFrontier
Sat 10/188:59 pmOMA - CLT
1 stop18h 40mFrontier
Deal found 9/16$226
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/910:11 pmCLT - OMA
1 stop19h 38mMultiple Airlines
Fri 11/147:04 pmOMA - CLT
1 stop17h 17mMultiple Airlines
Deal found 9/16$248
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/297:05 pmCHS - CID
1 stop4h 29mDelta
Thu 11/67:00 amCID - CHS
1 stop6h 12mDelta
Deal found 9/17$249
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:48 pmCAE - MLI
1 stop4h 41mAmerican Airlines
Sat 11/14:29 pmMLI - CAE
1 stop4h 35mAmerican Airlines
Deal found 9/14$249
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/225:36 pmGSP - CID
1 stop5h 58mDelta
Mon 10/276:00 amCID - GSP
1 stop5h 50mDelta
Deal found 9/15$249
This Trip.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/215:20 pmCLT - OMA
1 stop21h 01mFrontier
Thu 9/257:48 pmOMA - CLT
1 stop19h 55mFrontier
Deal found 9/15$249
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/285:35 amCHS - CID
2 stops11h 08mDelta
Thu 11/67:00 amCID - CHS
1 stop6h 12mDelta
Deal found 9/17$254
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/39:35 amGSP - CID
1 stop5h 37mUnited Airlines
Tue 10/76:47 amCID - GSP
1 stop3h 59mUnited Airlines
Deal found 9/15$254
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:45 amCLT - DSM
1 stop4h 20mDelta
Sat 10/116:05 amDSM - CLT
1 stop5h 06mDelta
Deal found 9/15$257
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/285:35 amCHS - CID
2 stops7h 10mDelta
Mon 11/312:31 pmCID - CHS
2 stops7h 20mDelta
Deal found 9/16$259
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3011:04 amCAE - MLI
1 stop5h 01mUnited Airlines
Sat 10/43:40 pmMLI - CAE
1 stop4h 50mUnited Airlines
Deal found 9/15$259

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from South Carolina to Iowa that are best for you.

Fly from

South Carolina

Fly to

Iowa

Route

Depart

Return

Price

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Thu 10/23

5:34 pm-8:04 pm

1 stop27h 30m

Omaha Eppley Airfield

Sun 10/26

8:59 pm-4:39 pm

1 stop18h 40m

$164

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Thu 10/30

7:05 pm-10:34 pm

1 stop4h 29m

Cedar Rapids

Tue 11/4

7:00 am-2:12 pm

1 stop6h 12m

$249

ColumbiaMoline

CAE - MLI

CAEMLI

Columbia Metropolitan

Tue 10/28

6:48 pm-10:29 pm

1 stop4h 41m

Moline Quad-City

Sat 11/1

4:29 pm-10:04 pm

1 stop4h 35m

$249

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Wed 10/8

3:55 pm-7:07 pm

1 stop4h 12m

Cedar Rapids

Sun 10/12

6:47 am-11:46 am

1 stop3h 59m

$249

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Wed 10/29

7:05 pm-10:34 pm

1 stop4h 29m

Cedar Rapids

Wed 11/5

6:00 am-1:25 pm

1 stop6h 25m

$249

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Wed 10/29

7:05 pm-10:34 pm

1 stop4h 29m

Cedar Rapids

Thu 11/6

7:00 am-2:12 pm

1 stop6h 12m

$249

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Wed 10/29

7:05 pm-10:34 pm

1 stop4h 29m

Cedar Rapids

Sun 11/2

5:00 am-10:46 am

1 stop4h 46m

$249

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Thu 10/30

7:05 pm-10:34 pm

1 stop4h 29m

Cedar Rapids

Thu 11/6

7:00 am-2:12 pm

1 stop6h 12m

$249

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

Fri 12/12

7:36 pm-10:37 pm

1 stop4h 01m

Cedar Rapids

Tue 12/16

5:50 am-11:16 am

1 stop4h 26m

$249

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Fri 10/31

10:21 am-4:54 pm

1 stop7h 33m

Cedar Rapids

Mon 11/3

3:13 pm-11:25 pm

2 stops7h 12m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Iowa

What is the cheapest month to book a flight from South Carolina to Iowa?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $336). Flying from South Carolina to Iowa in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IA?

Find hourly flight availability from South Carolina to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Iowa as you normally would.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated September 17, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from South Carolina to Iowa have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Iowa?

    Airlines like Frontier, Delta, and American Airlines fly from South Carolina to Iowa in about 4h 29m. The time it takes to get you to your destination can typically vary by up to 23h 01m. South Carolina and Iowa are separated by a distance of 890 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Iowa one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $116. Delta flights start at $129 while deals on American Airlines start at $149 one-way.

  • Can I find deals for flights from South Carolina to Iowa that include hotel bookings?

    Yes. In addition to deals on South Carolina to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Iowa.

  • Can I find deals for business class flights from South Carolina to Iowa?

    Yes. Cheapflights offers flight deals from South Carolina to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Iowa?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $336). Flying from South Carolina to Iowa in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Iowa

Discover the top 3 airlines that operate flights from South Carolina to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$204Average$392FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$337FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$366Average$626FlexibilityNo cancel feeOn-time69%

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