HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Iowa

$81+ Cheap flights from South Carolina to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
dic. 26 — ene. 21
vie. 12/26
vie. 1/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from South Carolina to Iowa

Cheapest flights from South Carolina to Iowa
Explore the most affordable flight options available from South Carolina to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 26, 2025.

This Priceline deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1812:17 pmCLT - OMA
1 stop8h 30mFrontier
lun. 1/511:11 amOMA - CLT
1 stop8h 47mFrontier
Deal found 11/23$213
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/304:55 pmSAV - CID
1 stop5h 39mUnited Airlines
mié. 1/73:10 pmCID - SAV
1 stop5h 26mUnited Airlines
Deal found 11/23$249
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/305:05 amSAV - CID
2 stops8h 05mAmerican Airlines
mié. 1/71:26 pmCID - SAV
2 stops9h 32mAmerican Airlines
Deal found 11/23$259
This Kiwi.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/245:14 pmCLT - OMA
1 stop27h 33mFrontier
mar. 12/308:42 pmOMA - CLT
1 stop18h 37mFrontier
Deal found 11/24$281
This Kiwi.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/228:54 amCLT - CID
1 stop10h 15mMultiple Airlines
lun. 12/297:14 pmCID - CLT
1 stop24h 25mMultiple Airlines
Deal found 11/24$291
This Mytrip deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/3010:02 pmCAE - CID
1 stop12h 25mAllegiant Air
vie. 1/27:16 pmCID - CAE
1 stop12h 00mAllegiant Air
Deal found 11/26$298
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/78:55 amCLT - DSM
1 stop14h 26mMultiple Airlines
vie. 12/128:00 amDSM - CLT
2 stops22h 57mMultiple Airlines
Deal found 11/23$310
This Delta deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/45:34 amCAE - CID
2 stops7h 08mDelta
dom. 12/75:50 amCID - CAE
1 stop5h 18mDelta
Deal found 11/23$314
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/256:20 amCAE - CID
1 stop5h 14mUnited Airlines
mié. 12/315:28 pmCID - CAE
1 stop5h 58mUnited Airlines
Deal found 11/24$319
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/228:54 amCLT - CID
1 stop10h 15mMultiple Airlines
jue. 1/112:48 pmCID - CLT
1 stop27h 53mMultiple Airlines
Deal found 11/25$321
This Kiwi.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/222:51 pmCLT - OMA
2 stops29h 56mFrontier
mar. 12/308:42 pmOMA - CLT
1 stop18h 37mFrontier
Deal found 11/24$323
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/78:55 amCLT - DSM
1 stop14h 26mMultiple Airlines
jue. 12/114:21 pmDSM - CLT
2 stops18h 36mMultiple Airlines
Deal found 11/23$325

Cheap flight deals from South Carolina to Iowa

Keep the following information in mind while searching for South Carolina to Iowa flight deals. Data was last updated noviembre 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$213
(Priceline)

One-way from

$81
(Frontier)
Provider with most accurate pricing for Myrtle Beach Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Des Moines flights.
Search Deals
From South Carolina to Iowa
Search Deals
One-way flight from South Carolina to Iowa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 26, 2025.
Use the filters below to find and compare flights from South Carolina to Iowa that are best for you.

Fly from

South Carolina

Fly to

Iowa

Route

Depart

Return

Price

SavannahCedar Rapids

SAV - CID

SAVCID

Savannah/Hilton Head

mar. 12/30

4:55 pm-9:34 pm

1 stop5h 39m

Cedar Rapids

mié. 1/7

3:10 pm-9:36 pm

1 stop5h 26m

$249

SavannahCedar Rapids

SAV - CID

SAVCID

Savannah/Hilton Head

sáb. 1/24

5:30 am-2:12 pm

2 stops9h 42m

Cedar Rapids

mié. 1/28

5:35 am-11:29 am

1 stop4h 54m

$254

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

sáb. 2/14

6:49 am-12:14 pm

1 stop6h 25m

Des Moines

mié. 2/18

7:34 am-5:14 pm

1 stop8h 40m

$289

CharlestonOmaha

CHS - OMA

CHSOMA

Charleston

mar. 2/24

5:27 am-10:04 am

1 stop5h 37m

Omaha Eppley Airfield

mié. 2/25

6:55 am-2:16 pm

1 stop6h 21m

$305

CharlestonOmaha

CHS - OMA

CHSOMA

Charleston

jue. 1/1

8:35 am-2:23 pm

1 stop6h 48m

Omaha Eppley Airfield

sáb. 1/10

10:34 am-5:43 pm

1 stop6h 09m

$316

ColumbiaCedar Rapids

CAE - CID

CAECID

Columbia Metropolitan

jue. 12/25

6:20 am-10:34 am

1 stop5h 14m

Cedar Rapids

mié. 12/31

5:28 pm-12:26 am

1 stop5h 58m

$319

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

mar. 1/13

7:50 am-11:12 am

1 stop4h 22m

Des Moines

sáb. 1/17

6:00 am-3:14 pm

2 stops8h 14m

$320

CharlotteCedar Rapids

CLT - CID

CLTCID

Charlotte Douglas

mié. 12/24

8:15 am-9:56 am

1 stop26h 41m

Cedar Rapids

mié. 12/31

10:26 am-8:04 am

1 stop20h 38m

$331

CharlestonOmaha

CHS - OMA

CHSOMA

Charleston

jue. 1/1

8:08 pm-11:59 pm

1 stop4h 51m

Omaha Eppley Airfield

sáb. 1/10

12:14 pm-9:11 pm

2 stops7h 57m

$331

CharlotteCedar Rapids

CLT - CID

CLTCID

Charlotte Douglas

lun. 12/22

8:54 am-6:09 pm

1 stop10h 15m

Cedar Rapids

lun. 12/29

7:14 pm-8:33 pm

2 stops24h 19m

$334

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/26

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from South Carolina to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Iowa

What is the cheapest month to book a flight from South Carolina to Iowa?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $162). Flying from South Carolina to Iowa in February is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IA?

Find hourly flight availability from South Carolina to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 26, 2025.

When flying from South Carolina to Iowa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 25% versus a flight in the morning.

What is the cheapest day to fly from South Carolina to Iowa?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Iowa. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Iowa flight should consider departing on Saturday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated noviembre 26, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from South Carolina to Iowa have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,046 reviews
Delta
7.9
Good
7,998 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,038 reviews
Delta
7.9
Good
7,998 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Iowa?

    Airlines like United Airlines, Delta, and American Airlines fly from South Carolina to Iowa in about 4h 22m. The time it takes to get you to your destination can typically vary by up to 5h 20m. South Carolina and Iowa are separated by a distance of 771 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Iowa one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $112. United Airlines flights start at $157 while deals on Delta start at $157 one-way.

  • Can I find deals for flights from South Carolina to Iowa that include hotel bookings?

    Yes. In addition to deals on South Carolina to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Iowa.

  • Can I find deals for business class flights from South Carolina to Iowa?

    Yes. Cheapflights offers flight deals from South Carolina to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Iowa?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $162). Flying from South Carolina to Iowa in February is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Fort Lauderdale flights
John F Kennedy Intl to Fort Lauderdale flights
Newark to Miami flights
John F Kennedy Intl to Miami flights
Los Angeles to John F Kennedy Intl flights
LaGuardia to Fort Lauderdale flights
LaGuardia to Miami flights
Dallas/Fort Worth to John F Kennedy Intl flights
John F Kennedy Intl to Los Angeles flights
Dallas/Fort Worth to LaGuardia flights
John F Kennedy Intl to Orlando flights
John F Kennedy Intl to Las Vegas flights
Dallas/Fort Worth to Newark flights
San Francisco to John F Kennedy Intl flights
John F Kennedy Intl to Dallas/Fort Worth flights
Newark to West Palm Beach flights
LaGuardia to Dallas/Fort Worth flights
Newark to Dallas/Fort Worth flights
Fort Lauderdale to Newark flights
Newark to Las Vegas flights
John F Kennedy Intl to West Palm Beach flights
Los Angeles to Newark flights
Newark to Orlando flights
John F Kennedy Intl to San Francisco flights
Seattle to Los Angeles flights
San Francisco to Newark flights
Dallas/Fort Worth to Las Vegas flights
Atlanta to John F Kennedy Intl flights
Orlando to John F Kennedy Intl flights
O'Hare Intl to Las Vegas flights
Los Angeles to Honolulu flights
Los Angeles to Seattle flights
Los Angeles to LaGuardia flights
Miami to John F Kennedy Intl flights
O'Hare Intl to John F Kennedy Intl flights
LaGuardia to Hobby flights
Atlanta to LaGuardia flights
Newark to Los Angeles flights
Fort Lauderdale to LaGuardia flights
Newark to Hobby flights
Hobby to John F Kennedy Intl flights
San Francisco to Las Vegas flights
Dulles Intl to Dallas/Fort Worth flights
LaGuardia to Orlando flights
Hobby to LaGuardia flights
Seattle to Las Vegas flights
Hobby to Newark flights
Miami to Newark flights
Newark to Tampa flights
Reagan-National to Miami flights

Top 3 airlines flying from South Carolina to Iowa

Discover the top 3 airlines that operate flights from South Carolina to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$204Average$386FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$344FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$268Average$452FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.