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Iowa

$89+ Cheap flights from South Carolina to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
Aug 22 — Aug 291
Fri 8/22
Fri 8/29
1 adult, Economy
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Cheap flight deals from South Carolina to Iowa

Keep the following information in mind while searching for South Carolina to Iowa flight deals. Data was last updated August 17, 2025.

Round-trip from

$195
(Kiwi.com)

One-way from

$89
(FlightHub)
From South Carolina to Iowa
Search Deals
One-way flight from South Carolina to Iowa
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Find flight deals from South Carolina to Iowa

Cheapest flights from South Carolina to Iowa
Explore the most affordable flight options available from South Carolina to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2025.

This FlightHub deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/145:20 pmCLT - DSM
1 stop21h 20mFrontier
Sun 9/212:25 pmDSM - CLT
1 stop25h 00mFrontier
Deal found 8/16$204
This FlightHub deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/154:00 pmCLT - OMA
1 stop19h 28mFrontier
Sun 10/198:59 pmOMA - CLT
1 stop18h 40mFrontier
Deal found 8/15$218
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/39:10 amCLT - DSM
1 stop6h 40mMultiple Airlines
Sun 10/58:47 pmDSM - CLT
1 stop18h 00mMultiple Airlines
Deal found 8/15$231
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/307:37 amSAV - OMA
1 stop6h 22mAmerican Airlines
Sat 9/65:24 pmOMA - SAV
1 stop4h 37mAmerican Airlines
Deal found 8/15$234
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/208:52 amCLT - DSM
1 stop6h 58mMultiple Airlines
Mon 10/278:30 amDSM - CLT
1 stop28h 05mMultiple Airlines
Deal found 8/17$238
This FlightHub deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:20 pmCLT - OMA
1 stop27h 30mFrontier
Sun 9/287:40 pmOMA - CLT
1 stop19h 45mFrontier
Deal found 8/16$239
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:50 pmCLT - DSM
1 stop4h 00mSouthwest
Mon 9/296:00 amDSM - CLT
1 stop10h 35mSouthwest
Deal found 8/14$242
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:27 amSAV - OMA
1 stop7h 43mAmerican Airlines
Mon 11/242:03 pmOMA - SAV
1 stop6h 13mAmerican Airlines
Deal found 8/17$247
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/32:58 pmCLT - CID
1 stop4h 21mMultiple Airlines
Sun 10/510:18 amCID - CLT
1 stop25h 12mMultiple Airlines
Deal found 8/16$248
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:59 pmCHS - CID
1 stop4h 44mDelta
Sun 10/55:57 amCID - CHS
1 stop4h 51mDelta
Deal found 8/15$249
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/254:06 pmCAE - DSM
1 stop6h 48mAmerican Airlines
Tue 9/307:00 amDSM - CAE
1 stop7h 35mAmerican Airlines
Deal found 8/17$249
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/167:05 amSAV - OMA
1 stop7h 07mAmerican Airlines
Tue 9/235:24 pmOMA - SAV
1 stop4h 39mAmerican Airlines
Deal found 8/17$251

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2025.
Use the filters below to find and compare flights from South Carolina to Iowa that are best for you.

Fly from

South Carolina

Fly to

Iowa

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sun 9/14

5:20 pm-1:40 pm

1 stop21h 20m

Des Moines

Sun 9/21

2:25 pm-4:25 pm

1 stop25h 00m

$204

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Wed 10/15

4:00 pm-10:28 am

1 stop19h 28m

Omaha Eppley Airfield

Sun 10/19

8:59 pm-4:39 pm

1 stop18h 40m

$218

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 10/3

9:10 am-2:50 pm

1 stop6h 40m

Des Moines

Sun 10/5

8:47 pm-3:47 pm

1 stop18h 00m

$231

SavannahOmaha

SAV - OMA

SAVOMA

Savannah/Hilton Head

Sat 8/30

7:37 am-12:59 pm

1 stop6h 22m

Omaha Eppley Airfield

Sat 9/6

5:24 pm-11:01 pm

1 stop4h 37m

$234

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 10/20

8:52 am-2:50 pm

1 stop6h 58m

Des Moines

Mon 10/27

8:30 am-1:35 pm

1 stop28h 05m

$238

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Thu 9/25

5:20 pm-7:50 pm

1 stop27h 30m

Omaha Eppley Airfield

Sun 9/28

7:40 pm-4:25 pm

1 stop19h 45m

$239

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 9/25

7:50 pm-10:50 pm

1 stop4h 00m

Des Moines

Mon 9/29

6:00 am-5:35 pm

1 stop10h 35m

$242

SavannahOmaha

SAV - OMA

SAVOMA

Savannah/Hilton Head

Fri 11/14

7:27 am-2:10 pm

1 stop7h 43m

Omaha Eppley Airfield

Mon 11/24

2:03 pm-9:16 pm

1 stop6h 13m

$247

CharlotteCedar Rapids

CLT - CID

CLTCID

Charlotte Douglas

Fri 10/3

2:58 pm-6:19 pm

1 stop4h 21m

Cedar Rapids

Sun 10/5

10:18 am-12:30 pm

1 stop25h 12m

$248

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Fri 10/3

4:44 pm-10:43 pm

1 stop6h 59m

Cedar Rapids

Sun 10/5

5:57 am-11:48 am

1 stop4h 51m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/15

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Iowa

What is the cheapest month to book a flight from South Carolina to Iowa?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $336). Flying from South Carolina to Iowa in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IA?

Find hourly flight availability from South Carolina to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Iowa as you normally would.

How much does it cost to fly round-trip from South Carolina to Iowa?

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated August 17, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from South Carolina to Iowa have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,986 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,986 reviews
Delta
8.0
Very good
7,986 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,919 reviews
Delta
8.0
Very good
7,986 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,986 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Iowa one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $89. Allegiant Air flights start at $106 while deals on American Airlines start at $139 one-way.

  • Can I find deals for flights from South Carolina to Iowa that include hotel bookings?

    Yes. In addition to deals on South Carolina to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Iowa.

  • Can I find deals for business class flights from South Carolina to Iowa?

    Yes. Cheapflights offers flight deals from South Carolina to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Iowa?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $336). Flying from South Carolina to Iowa in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Iowa

Discover the top 3 airlines that operate flights from South Carolina to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$204Average$389FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$329FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$366Average$626FlexibilityNo cancel feeOn-time69%

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