$97+ Cheap flights from South Carolina to Iowa
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
Jul 15 — Jul 221
Round-trip
1 adult, Economy
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Cheapest flights from South Carolina to IowaExplore the most affordable flight options available from South Carolina to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2026.
Explore the most affordable flight options available from South Carolina to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:41 pm
CLT
- CID
1 stop23h 24m
Multiple Airlines
Mon 7/275:55 pm
CID
- CLT
1 stop26h 12m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$241
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:10 am
CHS
- OMA
1 stop5h 32m
Delta
Tue 8/1110:40 am
OMA
- CHS
1 stop5h 58m
Delta
Deal found 6/11![Delta logo]()
$249
This Booking.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:14 pm
CLT
- OMA
1 stop22h 20m
Frontier
Fri 8/218:19 pm
OMA
- CLT
1 stop24h 05m
Frontier
Deal found 6/12![Frontier logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:41 pm
CLT
- DSM
1 stop22h 09m
Multiple Airlines
Mon 7/134:40 pm
DSM
- CLT
1 stop27h 27m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:02 pm
CLT
- DSM
1 stop24h 30m
Multiple Airlines
Mon 7/134:40 pm
DSM
- CLT
1 stop27h 27m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$262
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:35 pm
CLT
- DSM
1 stop4h 20m
Southwest
Tue 8/182:40 pm
DSM
- CLT
1 stop5h 30m
Southwest
Deal found 6/11![Southwest logo]()
$267
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:35 pm
CLT
- DSM
2 stops10h 20m
Southwest
Tue 8/252:40 pm
DSM
- CLT
1 stop5h 30m
Southwest
Deal found 6/11![Southwest logo]()
$272
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:21 pm
CHS
- OMA
1 stop5h 16m
American Airlines
Sat 8/86:14 am
OMA
- CHS
1 stop6h 02m
American Airlines
Deal found 6/11![American Airlines logo]()
$273
This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:04 pm
CLT
- OMA
1 stop22h 11m
Frontier
Sun 7/128:00 pm
OMA
- CLT
1 stop24h 19m
Frontier
Deal found 6/11![Frontier logo]()
$282
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:06 am
CAE
- OMA
1 stop6h 12m
American Airlines
Fri 7/31:45 pm
OMA
- CAE
1 stop5h 20m
American Airlines
Deal found 6/12![American Airlines logo]()
$285
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:10 pm
MYR
- DSM
1 stop5h 31m
American Airlines
Mon 10/56:04 am
DSM
- MYR
1 stop4h 52m
American Airlines
Deal found 6/10![American Airlines logo]()
$290
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:03 pm
CAE
- OMA
1 stop7h 16m
American Airlines
Sat 7/185:20 am
OMA
- CAE
1 stop7h 03m
American Airlines
Deal found 6/14![American Airlines logo]()
$291
Best flights from South Carolina to IowaDiscover carefully curated flight deals from South Carolina to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 15, 2026.
Discover carefully curated flight deals from South Carolina to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 15, 2026.
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:35 pm
CLT
- DSM
1 stop4h 20m
Southwest
Tue 8/186:10 am
DSM
- CLT
2 stops11h 50m
Southwest
Deal found 6/11![Southwest logo]()
$278
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:32 pm
GSP
- OMA
1 stop5h 47m
American Airlines
Wed 7/224:58 pm
OMA
- GSP
1 stop5h 18m
American Airlines
Deal found 6/13![American Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:30 pm
CHS
- OMA
1 stop5h 47m
Delta
Mon 11/26:30 pm
OMA
- CHS
1 stop4h 26m
Delta
Deal found 6/10![Delta logo]()
$322
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:30 am
GSP
- DSM
1 stop4h 56m
United Airlines
Wed 8/196:00 am
DSM
- GSP
2 stops7h 19m
United Airlines
Deal found 6/11![United Airlines logo]()
$350
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:20 am
MYR
- OMA
2 stops8h 35m
Southwest
Mon 11/28:15 am
OMA
- MYR
2 stops9h 40m
Southwest
Deal found 6/10![Southwest logo]()
$321
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:35 am
CAE
- OMA
1 stop5h 01m
Delta
Sat 7/115:25 am
OMA
- CAE
1 stop6h 34m
Delta
Deal found 6/10![Delta logo]()
$344
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:28 pm
GSP
- DSM
1 stop7h 30m
American Airlines
Wed 7/226:30 am
DSM
- GSP
1 stop4h 56m
American Airlines
Deal found 6/10![American Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:43 pm
GSP
- DSM
1 stop6h 13m
United Airlines
Sat 8/156:00 am
DSM
- GSP
2 stops7h 19m
United Airlines
Deal found 6/14![United Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:00 am
GSP
- OMA
2 stops6h 05m
Southwest
Mon 9/145:35 am
OMA
- GSP
2 stops9h 30m
Southwest
Deal found 6/15![Southwest logo]()
$347
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:29 pm
MYR
- OMA
1 stop6h 40m
American Airlines
Mon 11/26:11 am
OMA
- MYR
1 stop6h 48m
American Airlines
Deal found 6/10![American Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:30 am
CHS
- OMA
1 stop6h 50m
United Airlines
Wed 8/192:59 pm
OMA
- CHS
1 stop6h 12m
United Airlines
Deal found 6/10![United Airlines logo]()
$365
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am
MYR
- DSM
1 stop5h 43m
Delta
Sun 10/46:00 am
DSM
- MYR
1 stop4h 54m
Delta
Deal found 6/13![Delta logo]()
$372
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1711:50 am
CLT
- DSM
2 stops10h 25m
Southwest
Sat 8/227:20 am
DSM
- CLT
2 stops10h 00m
Southwest
Deal found 6/11![Southwest logo]()
$349
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:28 pm
GSP
- DSM
1 stop7h 31m
American Airlines
Tue 8/42:41 pm
DSM
- GSP
1 stop5h 54m
American Airlines
Deal found 6/14![American Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:43 pm
CHS
- OMA
1 stop5h 31m
United Airlines
Mon 11/21:08 pm
OMA
- CHS
2 stops9h 11m
United Airlines
Deal found 6/10![United Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:35 pm
CLT
- OMA
1 stop4h 10m
Southwest
Sat 8/85:30 am
OMA
- CLT
1 stop5h 50m
Southwest
Deal found 6/10![Southwest logo]()
$357
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:59 pm
CHS
- OMA
1 stop5h 08m
Delta
Sun 10/1810:55 am
OMA
- CHS
1 stop4h 41m
Delta
Deal found 6/12![Delta logo]()
$401
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:25 am
CAE
- OMA
1 stop4h 57m
United Airlines
Sat 8/223:11 pm
OMA
- CAE
1 stop5h 17m
United Airlines
Deal found 6/10![United Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:20 pm
GSP
- DSM
1 stop5h 41m
American Airlines
Tue 7/216:33 pm
DSM
- GSP
1 stop4h 25m
American Airlines
Deal found 6/10![American Airlines logo]()
$381
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:50 am
CLT
- DSM
2 stops10h 55m
Southwest
Wed 8/52:40 pm
DSM
- CLT
1 stop5h 30m
Southwest
Deal found 6/13![Southwest logo]()
$362
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:00 am
MYR
- DSM
1 stop5h 45m
Delta
Wed 7/156:37 pm
DSM
- MYR
1 stop4h 18m
Delta
Deal found 6/14![Delta logo]()
$402
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:43 pm
GSP
- OMA
1 stop5h 15m
United Airlines
Wed 8/196:02 am
OMA
- GSP
2 stops7h 17m
United Airlines
Deal found 6/10![United Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:56 pm
SAV
- OMA
2 stops7h 41m
American Airlines
Sat 7/255:05 pm
OMA
- SAV
1 stop5h 23m
American Airlines
Deal found 6/11![American Airlines logo]()
$381
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:50 am
CLT
- OMA
2 stops6h 55m
Southwest
Wed 7/221:10 pm
OMA
- CLT
1 stop7h 05m
Southwest
Deal found 6/12![Southwest logo]()
$362
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:02 pm
MYR
- OMA
1 stop5h 57m
Delta
Mon 8/175:30 am
OMA
- MYR
1 stop7h 03m
Delta
Deal found 6/13![Delta logo]()
$403
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:59 pm
SAV
- OMA
1 stop5h 26m
United Airlines
Wed 9/27:25 am
OMA
- SAV
1 stop6h 39m
United Airlines
Deal found 6/10![United Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:16 pm
MYR
- DSM
2 stops8h 45m
American Airlines
Tue 7/211:41 pm
DSM
- MYR
1 stop7h 02m
American Airlines
Deal found 6/10![American Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:45 am
CHS
- OMA
2 stops6h 00m
Southwest
Tue 9/2210:30 am
OMA
- CHS
2 stops8h 15m
Southwest
Deal found 6/14![Southwest logo]()
$364
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:44 pm
GSP
- OMA
1 stop5h 05m
Delta
Wed 7/227:01 am
OMA
- GSP
1 stop4h 13m
Delta
Deal found 6/12![Delta logo]()
$407
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/222:56 pm
CAE
- OMA
2 stops8h 02m
United Airlines
Wed 8/267:00 pm
OMA
- CAE
2 stops13h 47m
United Airlines
Deal found 6/14![United Airlines logo]()
$381
Last-minute flights from South Carolina to IowaDiscover last-minute flight deals from South Carolina to Iowa. Data last updated June 15, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Iowa. Data last updated June 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:33 pm
CLT
- DSM
2 stops27h 54m
Multiple Airlines
Mon 7/134:40 pm
DSM
- CLT
1 stop27h 27m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$298
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:06 am
CAE
- OMA
1 stop6h 12m
American Airlines
Fri 7/31:45 pm
OMA
- CAE
1 stop5h 20m
American Airlines
Deal found 6/12![American Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:02 pm
CLT
- DSM
1 stop24h 30m
Multiple Airlines
Mon 7/134:40 pm
DSM
- CLT
1 stop27h 27m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:41 pm
CLT
- DSM
1 stop22h 09m
Multiple Airlines
Mon 7/134:40 pm
DSM
- CLT
1 stop27h 27m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$254
This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:04 pm
CLT
- OMA
1 stop22h 11m
Frontier
Sun 7/128:00 pm
OMA
- CLT
1 stop24h 19m
Frontier
Deal found 6/11![Frontier logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/103:10 pm
GSP
- DSM
1 stop8h 05m
Multiple Airlines
Thu 7/165:08 pm
DSM
- GSP
2 stops20h 33m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$296
This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:04 pm
CLT
- OMA
1 stop22h 11m
Frontier
Sun 7/198:00 pm
OMA
- CLT
1 stop24h 19m
Frontier
Deal found 6/11![Frontier logo]()
$301
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:03 pm
CAE
- OMA
1 stop7h 16m
American Airlines
Sat 7/185:20 am
OMA
- CAE
1 stop7h 03m
American Airlines
Deal found 6/14![American Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:41 pm
CLT
- DSM
1 stop22h 09m
Multiple Airlines
Mon 7/204:40 pm
DSM
- CLT
1 stop27h 27m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$293
This Booking.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1710:04 pm
CLT
- OMA
1 stop22h 11m
Frontier
Sun 7/198:00 pm
OMA
- CLT
1 stop24h 19m
Frontier
Deal found 6/10![Frontier logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:41 pm
CLT
- CID
1 stop23h 24m
Multiple Airlines
Mon 7/275:55 pm
CID
- CLT
1 stop26h 12m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$241
This Gotogate deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2410:04 pm
CLT
- OMA
1 stop22h 11m
Frontier
Sun 8/28:00 pm
OMA
- CLT
1 stop24h 19m
Frontier
Deal found 6/10![Frontier logo]()
$300
One-way flights from South Carolina to IowaSearch for one-way flight options from South Carolina to Iowa. Find affordable one-way fares based on user searches. Data last updated June 15, 2026.
Search for one-way flight options from South Carolina to Iowa. Find affordable one-way fares based on user searches. Data last updated June 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:41 pm
CLT
- CID
1 stop23h 53m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:41 pm
CLT
- CID
1 stop23h 53m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:41 pm
CLT
- CID
1 stop23h 24m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:41 pm
CLT
- DSM
1 stop23h 36m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$129
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:35 pm
CLT
- DSM
1 stop4h 20m
Southwest
Deal found 6/11![Southwest logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:41 pm
CLT
- DSM
2 stops29h 38m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:41 pm
CLT
- DSM
2 stops29h 38m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:41 pm
CLT
- DSM
2 stops29h 26m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:41 pm
CLT
- CID
2 stops40h 04m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:01 pm
CLT
- DSM
2 stops26h 33m
Frontier
Deal found 6/10![Frontier logo]()
$147
This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:04 pm
CLT
- OMA
1 stop22h 11m
Frontier
Deal found 6/11![Frontier logo]()
$147
This Trip.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:04 pm
CLT
- CID
1 stop17h 02m
Frontier
Deal found 6/13![Frontier logo]()
$148
Find flight deals from South Carolina to Iowa
Keep the following information in mind while searching for South Carolina to Iowa flight deals. Data was last updated June 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $241 (Kiwi.com) |
One-way from | $97 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
Use the filters below to find and compare flights from South Carolina to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteDes Moines
CLT - DSM
CLTDSM
Charlotte Douglas
Tue 8/11
6:35 pm-9:55 pm
1 stop4h 20m
Des Moines
Tue 8/18
6:10 am-7:00 pm
2 stops11h 50m
$278
GreenvilleOmaha
GSP - OMA
GSPOMA
Greenville
Tue 7/14
7:32 pm-12:19 am
1 stop5h 47m
Omaha Eppley Airfield
Wed 7/22
4:58 pm-11:16 pm
1 stop5h 18m
$317
Myrtle BeachOmaha
MYR - OMA
MYROMA
Myrtle Beach Intl
Tue 10/27
8:20 am-3:55 pm
2 stops8h 35m
Omaha Eppley Airfield
Mon 11/2
8:15 am-6:55 pm
2 stops9h 40m
$321
CharlestonOmaha
CHS - OMA
CHSOMA
Charleston
Fri 10/30
4:30 pm-9:17 pm
1 stop5h 47m
Omaha Eppley Airfield
Mon 11/2
6:30 pm-11:56 pm
1 stop4h 26m
$322
ColumbiaOmaha
CAE - OMA
CAEOMA
Columbia Metropolitan
Sun 7/5
5:35 am-9:36 am
1 stop5h 01m
Omaha Eppley Airfield
Sat 7/11
5:25 am-12:59 pm
1 stop6h 34m
$344
GreenvilleOmaha
GSP - OMA
GSPOMA
Greenville
Wed 9/9
11:00 am-4:05 pm
2 stops6h 05m
Omaha Eppley Airfield
Mon 9/14
5:35 am-4:05 pm
2 stops9h 30m
$347
CharlotteDes Moines
CLT - DSM
CLTDSM
Charlotte Douglas
Mon 8/17
11:50 am-9:15 pm
2 stops10h 25m
Des Moines
Sat 8/22
7:20 am-6:20 pm
2 stops10h 00m
$349
GreenvilleDes Moines
GSP - DSM
GSPDSM
Greenville
Tue 8/18
6:30 am-10:26 am
1 stop4h 56m
Des Moines
Wed 8/19
6:00 am-2:19 pm
2 stops7h 19m
$350
GreenvilleDes Moines
GSP - DSM
GSPDSM
Greenville
Wed 7/8
5:28 pm-11:58 pm
1 stop7h 30m
Des Moines
Wed 7/22
6:30 am-12:26 pm
1 stop4h 56m
$355
CharlotteOmaha
CLT - OMA
CLTOMA
Charlotte Douglas
Tue 8/4
6:35 pm-9:45 pm
1 stop4h 10m
Omaha Eppley Airfield
Sat 8/8
5:30 am-12:20 pm
1 stop5h 50m
$357
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from South Carolina with our price prediction graph.
CLT-CID
CLT-DSM
CLT-OMA
CAE-OMA
GSP-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Iowa
USSC-USIA
CLT-CID
CLT-DSM
CLT-OMA
CAE-OMA
What is the cheapest month to book a flight from South Carolina to Iowa?
Currently, September is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $140). Flying from South Carolina to Iowa in June is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Carolina to Iowa?
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated June 15, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from South Carolina to Iowa have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.9
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.9
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.9
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.9
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Carolina to Iowa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Iowa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Iowa by cabin class
Find flights from South Carolina to Iowa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Iowa flights
Browse other South Carolina and Iowa flight options. Last updated on June 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Iowa
Find the right flight back to South Carolina after your stay in Iowa
South Carolina to Iowa flights
Consider these flights traveling from South Carolina to Iowa.
Top 3 airlines flying from South Carolina to Iowa
Discover the top 3 airlines that operate flights from South Carolina to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$140 | Average$407 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$219 | Average$400 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$326 | Average$626 | FlexibilityNo cancel fee | On-time69% |