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$164+ Cheap flights from Des Moines to Indianapolis (DSM - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Des Moines to Indianapolis

Cheapest flights from Des Moines to Indianapolis
Explore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:50 amDSM - IND
1 stop4h 17mDelta
Thu 12/186:45 amIND - DSM
1 stop4h 36mDelta
Deal found 10/29$251
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:56 pmDSM - IND
2 stops23h 14mMultiple Airlines
Thu 12/188:30 amIND - DSM
1 stop6h 36mMultiple Airlines
Deal found 10/29$284
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1210:55 amDSM - IND
1 stop20h 49mMultiple Airlines
Fri 11/145:05 amIND - DSM
1 stop10h 50mMultiple Airlines
Deal found 10/29$288
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:17 amDSM - IND
1 stop4h 12mDelta
Sat 12/206:35 amIND - DSM
1 stop5h 53mDelta
Deal found 10/29$289
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:45 amDSM - IND
2 stops9h 25mSouthwest
Tue 12/234:35 pmIND - DSM
1 stop7h 35mSouthwest
Deal found 10/30$300
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:58 pmDSM - IND
2 stops14h 26mMultiple Airlines
Sun 12/73:15 pmIND - DSM
1 stop8h 31mMultiple Airlines
Deal found 10/30$301
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/54:32 pmDSM - IND
1 stop19h 15mAllegiant Air
Sun 12/73:15 pmIND - DSM
1 stop8h 31mAllegiant Air
Deal found 10/30$321
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:59 pmDSM - IND
1 stop6h 31mDelta
Mon 12/226:35 amIND - DSM
1 stop5h 53mDelta
Deal found 10/30$327
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/510:55 amDSM - IND
1 stop20h 49mMultiple Airlines
Fri 11/75:05 amIND - DSM
1 stop10h 50mMultiple Airlines
Deal found 10/29$330

Cheap flight deals from Des Moines to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$251
(American Airlines)

One-way from

$164
(Delta)

Popular in

October

Cheapest in

September

Average price

$438
Provider with most accurate pricing for Des Moines-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Indianapolis flights.
Search Deals
From Des Moines to Indianapolis
Search Deals
One-way flight from Des Moines to Indianapolis
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($23 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.

Fly from

Des Moines

Fly to

Indianapolis

Route

Depart

Return

Price

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 12/11

6:50 am-12:07 pm

1 stop4h 17m

Indianapolis

Thu 12/18

6:45 am-10:21 am

1 stop4h 36m

$251

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 11/12

10:55 am-8:44 am

1 stop20h 49m

Indianapolis

Fri 11/14

5:05 am-2:55 pm

1 stop10h 50m

$288

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 1/29

8:00 am-1:18 pm

1 stop4h 18m

Indianapolis

Sun 2/1

11:25 am-2:33 pm

1 stop4h 08m

$289

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 12/18

6:17 am-11:29 am

1 stop4h 12m

Indianapolis

Mon 12/22

6:35 am-11:28 am

1 stop5h 53m

$289

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 12/13

6:17 am-1:31 pm

1 stop6h 14m

Indianapolis

Sat 12/20

6:35 am-11:28 am

1 stop5h 53m

$289

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 1/29

8:35 am-10:05 pm

2 stops12h 30m

Indianapolis

Sun 2/1

3:10 pm-9:20 pm

1 stop7h 10m

$294

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 12/18

5:45 am-4:10 pm

2 stops9h 25m

Indianapolis

Tue 12/23

4:35 pm-11:10 pm

1 stop7h 35m

$300

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 12/5

7:58 pm-11:24 am

2 stops14h 26m

Indianapolis

Sun 12/7

3:15 pm-10:46 pm

1 stop8h 31m

$301

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 12/5

4:32 pm-12:47 pm

1 stop19h 15m

Indianapolis

Sun 12/7

3:15 pm-10:46 pm

1 stop8h 31m

$321

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 4/18

10:55 am-3:36 pm

1 stop3h 41m

$164

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 21 results
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Compare providers for flights from Des Moines to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Indianapolis in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Indianapolis flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Des Moines-Indianapolis flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Des Moines-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Indianapolis flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indianapolis

What is the cheapest month to book a flight from Des Moines to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $130). Flying from Des Moines to Indianapolis in May is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IND?

Find hourly flight availability from Des Moines to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s optimal to fly from Des Moines to Indianapolis in the evening. By choosing this option you can save up to 82% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated October 30, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,998 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Indianapolis?

    A quick flight from Des Moines to Indianapolis can take about 4h 17m. Delta provides one of the quickest options available for as low as $251. Des Moines and Indianapolis are separated by a distance of 406 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Indianapolis round-trip?

    Our cheapest airline available from Des Moines to Indianapolis is American Airlines. Our recent data shows that you can find tickets from as low as $196 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $196 and $210 round-trip. You may be able to fly from Des Moines to Indianapolis for 41% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Des Moines to Indianapolis one-way?

    $164 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on Southwest and United Airlines, with prices starting from $169 and $174, respectively.

  • Can I find deals for flights from Des Moines to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indianapolis.

  • Can I find deals for business class flights from Des Moines to Indianapolis?

    Yes. Cheapflights offers flight deals from Des Moines to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $130). Flying from Des Moines to Indianapolis in May is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Noblesville
Fishers
Greenwood
Anderson
Kokomo
Bloomington
Plainfield
Franklin
Carmel
Crawfordsville
Speedway

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Top 3 airlines flying from Des Moines to Indianapolis

Discover the top 3 airlines that operate flights from Des Moines to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$311FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$341FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$210Average$386FlexibilityNo cancel feeOn-time69%

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