$114+ Cheap flights from Des Moines to Indianapolis (DSM - IND)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
May 24 — May 311
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to IndianapolisExplore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
Explore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:15 pm
DSM
- IND
1 stop3h 50m
United Airlines
Wed 6/37:59 pm
IND
- DSM
1 stop4h 17m
United Airlines
Deal found 4/21![United Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/244:41 pm
DSM
- IND
2 stops41h 40m
Multiple Airlines
Mon 6/82:49 pm
IND
- DSM
1 stop9h 38m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$264
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:20 pm
DSM
- IND
1 stop3h 48m
United Airlines
Thu 5/147:15 am
IND
- DSM
1 stop4h 22m
United Airlines
Deal found 4/22![United Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/295:45 pm
DSM
- IND
1 stop17h 13m
Allegiant Air
Fri 7/31:14 pm
IND
- DSM
1 stop10h 16m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$273
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:00 am
DSM
- IND
1 stop4h 28m
United Airlines
Fri 6/126:00 am
IND
- DSM
1 stop5h 27m
United Airlines
Deal found 4/22![United Airlines logo]()
$287
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:02 am
DSM
- IND
1 stop4h 01m
United Airlines
Thu 5/147:15 am
IND
- DSM
1 stop4h 22m
United Airlines
Deal found 4/23![United Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:04 pm
DSM
- IND
1 stop4h 30m
Delta
Fri 5/295:45 pm
IND
- DSM
1 stop3h 51m
Delta
Deal found 4/21![Delta logo]()
$295
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/98:03 pm
DSM
- IND
1 stop3h 50m
American Airlines
Fri 6/125:10 am
IND
- DSM
1 stop4h 02m
American Airlines
Deal found 4/22![American Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:30 am
DSM
- IND
1 stop5h 40m
Southwest
Tue 9/2212:15 pm
IND
- DSM
2 stops10h 40m
Southwest
Deal found 4/22![Southwest logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:35 am
DSM
- IND
1 stop11h 06m
Multiple Airlines
Mon 6/111:02 am
IND
- DSM
1 stop13h 22m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$300
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:30 am
DSM
- IND
2 stops6h 10m
Southwest
Thu 5/146:00 pm
IND
- DSM
1 stop6h 05m
Southwest
Deal found 4/23![Southwest logo]()
$301
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:24 pm
DSM
- IND
1 stop3h 39m
American Airlines
Fri 5/157:43 pm
IND
- DSM
1 stop5h 06m
American Airlines
Deal found 4/20![American Airlines logo]()
$302
Best flights from Des Moines to IndianapolisDiscover carefully curated flight deals from Des Moines to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
Discover carefully curated flight deals from Des Moines to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:00 am
DSM
- IND
1 stop4h 28m
United Airlines
Fri 6/126:00 am
IND
- DSM
1 stop5h 27m
United Airlines
Deal found 4/22![United Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:10 am
DSM
- IND
1 stop5h 55m
Southwest
Tue 6/95:20 am
IND
- DSM
2 stops7h 10m
Southwest
Deal found 4/19![Southwest logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:16 pm
DSM
- IND
1 stop28h 50m
Multiple Airlines
Mon 6/151:49 pm
IND
- DSM
1 stop10h 04m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$316
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:25 am
DSM
- IND
1 stop6h 05m
Southwest
Fri 5/296:35 pm
IND
- DSM
2 stops5h 30m
Southwest
Deal found 4/21![Southwest logo]()
$308
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:15 pm
DSM
- IND
1 stop3h 50m
United Airlines
Thu 6/46:00 am
IND
- DSM
1 stop5h 27m
United Airlines
Deal found 4/20![United Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:00 am
DSM
- IND
1 stop5h 54m
United Airlines
Tue 6/304:25 pm
IND
- DSM
1 stop4h 00m
United Airlines
Deal found 4/21![United Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/154:40 pm
DSM
- IND
1 stop5h 45m
Southwest
Wed 6/176:40 am
IND
- DSM
1 stop5h 50m
Southwest
Deal found 4/23![Southwest logo]()
$357
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:30 pm
DSM
- IND
1 stop3h 50m
United Airlines
Sun 6/289:15 pm
IND
- DSM
1 stop4h 30m
United Airlines
Deal found 4/21![United Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:30 pm
DSM
- IND
1 stop5h 47m
United Airlines
Tue 5/127:15 am
IND
- DSM
1 stop4h 22m
United Airlines
Deal found 4/23![United Airlines logo]()
$362
Last-minute flights from Des Moines to IndianapolisDiscover last-minute flight deals from Des Moines to Indianapolis. Data last updated April 24, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Indianapolis. Data last updated April 24, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:02 am
DSM
- IND
1 stop4h 01m
United Airlines
Thu 5/147:15 am
IND
- DSM
1 stop4h 22m
United Airlines
Deal found 4/23![United Airlines logo]()
$290
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:30 am
DSM
- IND
2 stops6h 10m
Southwest
Thu 5/146:00 pm
IND
- DSM
1 stop6h 05m
Southwest
Deal found 4/23![Southwest logo]()
$301
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:20 pm
DSM
- IND
1 stop3h 48m
United Airlines
Thu 5/147:15 am
IND
- DSM
1 stop4h 22m
United Airlines
Deal found 4/22![United Airlines logo]()
$272
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:24 pm
DSM
- IND
1 stop3h 39m
American Airlines
Fri 5/157:43 pm
IND
- DSM
1 stop5h 06m
American Airlines
Deal found 4/20![American Airlines logo]()
$302
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
DSM
- IND
1 stop6h 10m
American Airlines
Tue 5/265:10 am
IND
- DSM
1 stop4h 03m
American Airlines
Deal found 4/19![American Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/244:41 pm
DSM
- IND
2 stops41h 40m
Multiple Airlines
Mon 6/82:49 pm
IND
- DSM
1 stop9h 38m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:04 pm
DSM
- IND
1 stop4h 30m
Delta
Fri 5/295:45 pm
IND
- DSM
1 stop3h 51m
Delta
Deal found 4/21![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:25 am
DSM
- IND
1 stop6h 05m
Southwest
Fri 5/296:35 pm
IND
- DSM
2 stops5h 30m
Southwest
Deal found 4/21![Southwest logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:35 am
DSM
- IND
1 stop11h 06m
Multiple Airlines
Mon 6/111:02 am
IND
- DSM
1 stop13h 22m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:00 am
DSM
- IND
1 stop5h 31m
American Airlines
Mon 6/17:47 pm
IND
- DSM
1 stop5h 21m
American Airlines
Deal found 4/20![American Airlines logo]()
$310
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:10 pm
DSM
- IND
1 stop4h 45m
American Airlines
Wed 6/35:30 pm
IND
- DSM
1 stop7h 47m
American Airlines
Deal found 4/21![American Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3110:26 pm
DSM
- IND
2 stops17h 03m
Multiple Airlines
Wed 6/33:57 pm
IND
- DSM
1 stop17h 40m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$312
One-way flights from Des Moines to IndianapolisSearch for one-way flight options from Des Moines to Indianapolis. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
Search for one-way flight options from Des Moines to Indianapolis. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:55 am
DSM
- IND
1 stop5h 20m
Southwest
Deal found 4/19![Southwest logo]()
$114
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:44 am
DSM
- IND
1 stop5h 05m
American Airlines
Deal found 4/21![American Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:44 pm
DSM
- IND
1 stop15h 37m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$133
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:00 am
DSM
- IND
1 stop6h 54m
United Airlines
Deal found 4/21![United Airlines logo]()
$174
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:10 am
DSM
- IND
2 stops6h 05m
Southwest
Deal found 4/21![Southwest logo]()
$189
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:10 am
DSM
- IND
2 stops6h 10m
Southwest
Deal found 4/21![Southwest logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/214:41 pm
DSM
- IND
2 stops41h 40m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$204
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:30 am
DSM
- IND
2 stops6h 10m
Southwest
Deal found 4/21![Southwest logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/302:36 pm
DSM
- IND
1 stop26h 14m
Allegiant Air
Deal found 4/22![Allegiant Air logo]()
$215
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:34 am
DSM
- IND
1 stop3h 42m
Delta
Deal found 4/20![Delta logo]()
$224
Find flight deals from Des Moines to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $250 (United Airlines) |
One-way from | $114 (Southwest) |
Popular in | March |
Cheapest in | September |
Average price | $297 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Wed 6/10
5:00 am-10:28 am
1 stop4h 28m
Indianapolis
Fri 6/12
6:00 am-10:27 am
1 stop5h 27m
$287
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Fri 6/5
5:10 am-12:05 pm
1 stop5h 55m
Indianapolis
Tue 6/9
5:20 am-11:30 am
2 stops7h 10m
$305
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Thu 5/28
5:25 am-12:30 pm
1 stop6h 05m
Indianapolis
Fri 5/29
6:35 pm-11:05 pm
2 stops5h 30m
$308
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Mon 6/8
2:16 pm-8:06 pm
1 stop28h 50m
Indianapolis
Mon 6/15
1:49 pm-10:53 pm
1 stop10h 04m
$316
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Mon 6/1
8:15 pm-1:05 am
1 stop3h 50m
Indianapolis
Thu 6/4
6:00 am-10:27 am
1 stop5h 27m
$343
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Thu 6/25
6:00 am-12:54 pm
1 stop5h 54m
Indianapolis
Tue 6/30
4:25 pm-7:25 pm
1 stop4h 00m
$347
Quickest round-trip
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Fri 6/26
8:30 pm-1:20 am
1 stop3h 50m
Indianapolis
Sun 6/28
9:15 pm-12:45 am
1 stop4h 30m
$347
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Mon 6/15
4:40 pm-11:25 pm
1 stop5h 45m
Indianapolis
Wed 6/17
6:40 am-11:30 am
1 stop5h 50m
$357
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Fri 5/8
3:30 pm-10:17 pm
1 stop5h 47m
Indianapolis
Tue 5/12
7:15 am-10:37 am
1 stop4h 22m
$362
Cheapest one-way
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Tue 6/2
6:55 am-1:15 pm
1 stop5h 20m
$114
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Indianapolis in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Des Moines with our price prediction graph.
DSM-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Indianapolis
What is the cheapest month to book a flight from Des Moines to Indianapolis?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $251). Flying from Des Moines to Indianapolis in March is currently the most expensive (average of $586). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Indianapolis?
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated April 24, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Des Moines to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Overall
7.9
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Overall
7.9
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Overall
7.9
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Overall
7.9
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Muncie
Greenwood
Fishers
Kokomo
Plainfield
Mooresville
Anderson
Franklin
Carmel
Noblesville
Bloomington
Crawfordsville
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Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 24, 2026.
Des Moines and Indianapolis flights
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Other flights from Des Moines
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Top 3 airlines flying from Des Moines to Indianapolis
Discover the top 3 airlines that operate flights from Des Moines to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$196 | Average$321 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$196 | Average$308 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$210 | Average$358 | FlexibilityNo cancel fee | On-time69% |