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$139+ Cheap flights from Des Moines to Indianapolis (DSM - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Mar 17 — Mar 241
Tue 3/17
Tue 3/24
1 adult, Economy
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Cheap flight deals from Des Moines to Indianapolis

Cheapest flights from Des Moines to Indianapolis
Explore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 15, 2026.

This Frontier deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/811:00 am
DSM
-
IND
1 stop26h 15m
Frontier
Mon 3/165:18 pm
IND
-
DSM
1 stop17h 27m
Frontier
Deal found 2/14$250
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/293:21 pm
DSM
-
IND
1 stop3h 41m
United Airlines
Sat 5/210:15 am
IND
-
DSM
1 stop5h 09m
United Airlines
Deal found 2/12$251
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:04 pm
DSM
-
IND
1 stop3h 46m
United Airlines
Thu 3/269:00 am
IND
-
DSM
1 stop6h 24m
United Airlines
Deal found 2/12$264
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:55 am
DSM
-
IND
1 stop3h 40m
Delta
Sat 3/286:13 am
IND
-
DSM
1 stop4h 46m
Delta
Deal found 2/14$277
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/118:21 pm
DSM
-
IND
1 stop22h 17m
Frontier
Sun 3/158:33 pm
IND
-
DSM
1 stop23h 43m
Frontier
Deal found 2/11$287
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:34 am
DSM
-
IND
1 stop5h 44m
Delta
Fri 4/246:13 am
IND
-
DSM
1 stop4h 41m
Delta
Deal found 2/13$289
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/47:44 pm
DSM
-
IND
1 stop3h 34m
American Airlines
Fri 3/68:00 am
IND
-
DSM
1 stop6h 17m
American Airlines
Deal found 2/11$299
This Southwest deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:30 am
DSM
-
IND
1 stop5h 35m
Southwest
Thu 3/2612:15 pm
IND
-
DSM
2 stops12h 00m
Southwest
Deal found 2/12$300
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:03 pm
DSM
-
IND
1 stop3h 28m
American Airlines
Sun 5/105:55 am
IND
-
DSM
1 stop5h 31m
American Airlines
Deal found 2/11$302
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:40 am
DSM
-
IND
1 stop5h 45m
American Airlines
Mon 4/67:17 pm
IND
-
DSM
1 stop5h 25m
American Airlines
Deal found 2/13$303

Find flight deals from Des Moines to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$250
(Frontier)

One-way from

$139
(Delta)

Popular in

November

Cheapest in

September

Average price

$308
Provider with most accurate pricing for Des Moines-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Indianapolis flights.
Search Deals
From Des Moines to Indianapolis
Search Deals
One-way flight from Des Moines to Indianapolis
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 15, 2026.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.

Fly from

Des Moines

Fly to

Indianapolis

Route

Depart

Return

Price

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sun 3/8

11:00 am-2:15 pm

1 stop26h 15m

Indianapolis

Mon 3/16

5:18 pm-9:45 am

1 stop17h 27m

$250

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 3/31

7:44 pm-12:16 am

1 stop3h 32m

Indianapolis

Tue 4/7

1:50 pm-4:31 pm

1 stop3h 41m

$250

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 4/28

10:58 am-4:34 pm

1 stop4h 36m

Indianapolis

Sat 5/2

6:13 am-9:54 am

1 stop4h 41m

$251

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 4/29

3:21 pm-8:02 pm

1 stop3h 41m

Indianapolis

Sat 5/2

10:15 am-2:24 pm

1 stop5h 09m

$251

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 3/24

2:04 pm-6:50 pm

1 stop3h 46m

Indianapolis

Thu 3/26

9:00 am-2:24 pm

1 stop6h 24m

$264

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 3/24

6:55 am-11:35 am

1 stop3h 40m

Indianapolis

Thu 3/26

6:13 am-9:46 am

1 stop4h 33m

$264

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 3/28

4:25 pm-11:47 pm

1 stop6h 22m

Indianapolis

Sat 4/4

12:17 pm-4:54 pm

1 stop5h 37m

$277

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 3/26

6:55 am-11:35 am

1 stop3h 40m

Indianapolis

Sat 3/28

6:13 am-9:59 am

1 stop4h 46m

$277

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 3/11

8:21 pm-7:38 pm

1 stop22h 17m

Indianapolis

Sun 3/15

8:33 pm-7:16 pm

1 stop23h 43m

$287

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 4/22

10:34 am-5:18 pm

1 stop5h 44m

Indianapolis

Fri 4/24

6:13 am-9:54 am

1 stop4h 41m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 21 results
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2
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Compare providers for flights from Des Moines to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Indianapolis in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indianapolis

What is the cheapest month to book a flight from Des Moines to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $130). Flying from Des Moines to Indianapolis in January is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated February 15, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,205 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,205 reviews
Delta
7.9
Good
8,205 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,296 reviews
Delta
7.9
Good
8,205 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,297 reviews
Delta
7.9
Good
8,205 reviews

Boarding

8.1

Entertainment

7.8

Food

7.2

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Indianapolis?

    A quick flight from Des Moines to Indianapolis can take about 3h 32m. Frontier provides one of the quickest options available for as low as $250. Des Moines and Indianapolis are separated by a distance of 406 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Indianapolis round-trip?

    Our cheapest airline available from Des Moines to Indianapolis is Delta. Our recent data shows that you can find tickets from as low as $179 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $196 and $196 round-trip. You may be able to fly from Des Moines to Indianapolis for 45% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Des Moines to Indianapolis one-way?

    $98 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $123 and $125, respectively.

  • Can I find deals for flights from Des Moines to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indianapolis.

  • Can I find deals for business class flights from Des Moines to Indianapolis?

    Yes. Cheapflights offers flight deals from Des Moines to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $130). Flying from Des Moines to Indianapolis in January is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Noblesville
Greenwood
Plainfield
Anderson
Kokomo
Mooresville
Franklin
Carmel
Crawfordsville
Bloomington

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Des Moines to Indianapolis

Discover the top 3 airlines that operate flights from Des Moines to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$179Average$309FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$196Average$358FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$196Average$318FlexibilityNo cancel feeOn-time71%

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