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$123+ Cheap flights from Des Moines to Indianapolis (DSM - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Des Moines to Indianapolis

Cheapest flights from Des Moines to Indianapolis
Explore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/238:19 pmDSM - IND
1 stop21h 55mMultiple Airlines
Wed 11/268:46 amIND - DSM
1 stop25h 15mMultiple Airlines
Deal found 11/11$234
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:15 amDSM - IND
1 stop28h 54mAllegiant Air
Thu 12/188:30 amIND - DSM
1 stop6h 36mAllegiant Air
Deal found 11/13$245
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:56 pmDSM - IND
2 stops23h 14mMultiple Airlines
Thu 12/188:30 amIND - DSM
1 stop6h 36mMultiple Airlines
Deal found 11/13$260
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:50 pmDSM - IND
1 stop3h 48mUnited Airlines
Tue 12/167:15 amIND - DSM
1 stop4h 38mUnited Airlines
Deal found 11/13$264
This Southwest deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/158:20 amDSM - IND
1 stop8h 15mSouthwest
Tue 12/161:10 pmIND - DSM
2 stops9h 25mSouthwest
Deal found 11/13$269
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/54:32 pmDSM - IND
1 stop19h 15mAllegiant Air
Sun 12/73:15 pmIND - DSM
1 stop8h 31mAllegiant Air
Deal found 11/12$286
This Southwest deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:15 amDSM - IND
2 stops9h 10mSouthwest
Thu 12/186:10 pmIND - DSM
2 stops6h 25mSouthwest
Deal found 11/13$287
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/183:55 pmDSM - IND
1 stop5h 57mAmerican Airlines
Tue 12/238:11 pmIND - DSM
1 stop5h 26mAmerican Airlines
Deal found 11/12$292
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:56 pmDSM - IND
1 stop19h 02mMultiple Airlines
Sun 12/73:15 pmIND - DSM
1 stop8h 31mMultiple Airlines
Deal found 11/12$299
This Mytrip deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/209:19 amDSM - IND
1 stop13h 00mMultiple Airlines
Sun 11/238:00 amIND - DSM
1 stop14h 14mMultiple Airlines
Deal found 11/13$300
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:58 pmDSM - IND
2 stops14h 26mMultiple Airlines
Sun 12/73:15 pmIND - DSM
1 stop8h 31mMultiple Airlines
Deal found 11/12$303

Cheap flight deals from Des Moines to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$234
(Kiwi.com)

One-way from

$123
(Kiwi.com)

Popular in

June

Cheapest in

September

Average price

$386
Provider with most accurate pricing for Des Moines-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Indianapolis flights.
Search Deals
From Des Moines to Indianapolis
Search Deals
One-way flight from Des Moines to Indianapolis
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.

Fly from

Des Moines

Fly to

Indianapolis

Route

Depart

Return

Price

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sun 11/23

8:19 pm-7:14 pm

1 stop21h 55m

Indianapolis

Wed 11/26

8:46 am-9:01 am

1 stop25h 15m

$234

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 12/11

2:56 pm-3:10 pm

2 stops23h 14m

Indianapolis

Thu 12/18

8:30 am-2:06 pm

1 stop6h 36m

$260

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 12/15

6:50 pm-11:38 pm

1 stop3h 48m

Indianapolis

Tue 12/16

7:15 am-10:53 am

1 stop4h 38m

$264

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 12/15

8:20 am-5:35 pm

1 stop8h 15m

Indianapolis

Tue 12/16

1:10 pm-9:35 pm

2 stops9h 25m

$269

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 12/5

4:32 pm-12:47 pm

1 stop19h 15m

Indianapolis

Sun 12/7

3:15 pm-10:46 pm

1 stop8h 31m

$286

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 12/11

6:15 am-4:25 pm

2 stops9h 10m

Indianapolis

Thu 12/18

6:10 pm-11:35 pm

2 stops6h 25m

$287

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 1/16

4:00 pm-10:54 pm

1 stop5h 54m

Indianapolis

Sun 1/18

6:00 am-10:50 am

1 stop5h 50m

$289

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 12/18

5:45 am-1:42 pm

1 stop6h 57m

Indianapolis

Tue 12/23

8:11 pm-12:37 am

1 stop5h 26m

$292

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 12/4

2:56 pm-10:58 am

1 stop19h 02m

Indianapolis

Sun 12/7

3:15 pm-10:46 pm

1 stop8h 31m

$299

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 1/12

6:48 pm-11:30 pm

1 stop3h 42m

Indianapolis

Fri 1/16

6:00 pm-9:50 pm

1 stop4h 50m

$302

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 20 results
1
2

Compare providers for flights from Des Moines to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Indianapolis in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Indianapolis flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Des Moines-Indianapolis flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Des Moines-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Indianapolis flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indianapolis

What is the cheapest month to book a flight from Des Moines to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $130). Flying from Des Moines to Indianapolis in May is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IND?

Find hourly flight availability from Des Moines to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

It’s optimal to fly from Des Moines to Indianapolis in the evening. By choosing this option you can save up to 82% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated November 13, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,017 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Indianapolis?

    A quick flight from Des Moines to Indianapolis can take about 3h 48m. United Airlines provides one of the quickest options available for as low as $264. Des Moines and Indianapolis are separated by a distance of 406 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Indianapolis round-trip?

    Our cheapest airline available from Des Moines to Indianapolis is American Airlines. Our recent data shows that you can find tickets from as low as $196 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $196 and $210 round-trip. You may be able to fly from Des Moines to Indianapolis for 39% less than the average price by searching for these airlines.

  • Can I find deals for flights from Des Moines to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indianapolis.

  • Can I find deals for business class flights from Des Moines to Indianapolis?

    Yes. Cheapflights offers flight deals from Des Moines to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $130). Flying from Des Moines to Indianapolis in May is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Noblesville
Fishers
Greenwood
Anderson
Kokomo
Bloomington
Plainfield
Franklin
Carmel
Crawfordsville
Speedway

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Alternative routes for Des Moines to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Des Moines to Indianapolis

Discover the top 3 airlines that operate flights from Des Moines to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$308FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$327FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$210Average$386FlexibilityNo cancel feeOn-time69%

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