$87+ Cheap flights from Des Moines to Indianapolis (DSM - IND)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Sep 17 — Sep 241
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Indianapolis
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Cheapest flights from Des Moines to IndianapolisExplore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2026.
Explore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:30 pm -
1 stop17h 47m
Wed 9/234:12 pm -
1 stop19h 32m
Deal found 8/14![Frontier logo]()
$250
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am -
1 stop4h 31m
Wed 9/236:35 am -
1 stop4h 03m
Deal found 8/17![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:50 pm -
1 stop5h 50m
Tue 9/2212:15 pm -
2 stops10h 45m
Deal found 8/14![Southwest logo]()
$262
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:30 am -
2 stops15h 10m
Mon 9/215:00 pm -
1 stop6h 15m
Deal found 8/15![Southwest logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm -
2 stops21h 23m
Thu 9/248:56 pm -
1 stop23h 37m
Deal found 8/14![Frontier logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:51 pm -
1 stop22h 06m
Mon 11/912:39 pm -
2 stops50h 16m
Deal found 8/15![Multiple Airlines logo]()
$275
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:59 pm -
1 stop4h 06m
Fri 9/256:35 am -
1 stop4h 03m
Deal found 8/14![Delta logo]()
$278
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:10 am -
2 stops8h 55m
Thu 10/85:55 pm -
1 stop6h 00m
Deal found 8/16![Southwest logo]()
$283
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:40 am -
2 stops8h 10m
Mon 9/281:15 pm -
2 stops10h 00m
Deal found 8/14![Southwest logo]()
$288
Best flights from Des Moines to IndianapolisDiscover carefully curated flight deals from Des Moines to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 18, 2026.
Discover carefully curated flight deals from Des Moines to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 18, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:05 am -
1 stop4h 14m
Mon 9/288:52 pm -
1 stop4h 12m
Deal found 8/17![American Airlines logo]()
$257
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:50 pm -
1 stop5h 50m
Tue 9/2212:15 pm -
2 stops10h 45m
Deal found 8/14![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:59 pm -
1 stop4h 06m
Fri 9/256:35 am -
1 stop4h 03m
Deal found 8/14![Delta logo]()
$278
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:56 pm -
1 stop4h 13m
Tue 9/228:52 pm -
1 stop4h 12m
Deal found 8/14![American Airlines logo]()
$257
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:50 pm -
1 stop5h 50m
Wed 9/2312:15 pm -
2 stops10h 45m
Deal found 8/14![Southwest logo]()
$262
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:30 am -
2 stops15h 10m
Mon 9/215:00 pm -
1 stop6h 15m
Deal found 8/15![Southwest logo]()
$268
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:29 pm -
1 stop5h 44m
Sun 11/226:35 am -
1 stop4h 44m
Deal found 8/13![Delta logo]()
$295
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:56 pm -
1 stop4h 13m
Fri 9/258:52 pm -
1 stop4h 12m
Deal found 8/17![American Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:50 pm -
1 stop5h 50m
Fri 9/185:00 pm -
1 stop6h 15m
Deal found 8/18![Southwest logo]()
$278
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:40 am -
1 stop5h 30m
Mon 9/281:15 pm -
2 stops10h 00m
Deal found 8/14![Southwest logo]()
$283
Last-minute flights from Des Moines to IndianapolisDiscover last-minute flight deals from Des Moines to Indianapolis. Data last updated August 18, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Indianapolis. Data last updated August 18, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am -
1 stop4h 31m
Wed 9/236:35 am -
1 stop4h 03m
Deal found 8/17![Delta logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm -
2 stops21h 23m
Thu 9/248:56 pm -
1 stop23h 37m
Deal found 8/14![Frontier logo]()
$273
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:30 am -
2 stops15h 10m
Mon 9/215:00 pm -
1 stop6h 15m
Deal found 8/15![Southwest logo]()
$268
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am -
1 stop4h 31m
Thu 9/247:00 am -
1 stop4h 17m
Deal found 8/13![Delta logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:30 pm -
1 stop17h 47m
Wed 9/234:12 pm -
1 stop19h 32m
Deal found 8/14![Frontier logo]()
$250
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:50 pm -
1 stop5h 50m
Tue 9/2212:15 pm -
2 stops10h 45m
Deal found 8/14![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:59 pm -
1 stop4h 06m
Fri 9/256:35 am -
1 stop4h 03m
Deal found 8/14![Delta logo]()
$278
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:40 am -
1 stop5h 30m
Mon 9/281:15 pm -
2 stops10h 00m
Deal found 8/14![Southwest logo]()
$283
One-way flights from Des Moines to IndianapolisSearch for one-way flight options from Des Moines to Indianapolis. Find affordable one-way fares based on user searches. Data last updated August 18, 2026.
Search for one-way flight options from Des Moines to Indianapolis. Find affordable one-way fares based on user searches. Data last updated August 18, 2026.
This Jetabroad deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Jetabroad is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:30 pm -
1 stop17h 47m
Deal found 8/15![Frontier logo]()
$87
This Jetabroad deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Jetabroad is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:25 pm -
1 stop17h 48m
Deal found 8/14![Frontier logo]()
$107
This Jetabroad deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Jetabroad is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:51 pm -
1 stop22h 06m
Deal found 8/17![Frontier logo]()
$109
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:00 am -
1 stop3h 35m
Deal found 8/13![Delta logo]()
$118
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:10 am -
2 stops9h 45m
Deal found 8/15![Southwest logo]()
$134
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:40 am -
2 stops12h 15m
Deal found 8/15![Southwest logo]()
$140
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:27 am -
1 stop4h 07m
Deal found 8/16![United Airlines logo]()
$150
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:10 am -
2 stops8h 55m
Deal found 8/16![Southwest logo]()
$155
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:40 am -
2 stops15h 45m
Deal found 8/17![Southwest logo]()
$166
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:10 am -
2 stops9h 10m
Deal found 8/16![Southwest logo]()
$184
Find flight deals from Des Moines to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $250 (Kiwi.com) |
One-way from | $87 (Jetabroad) |
Popular in | May |
Cheapest in | September |
Average price | $453 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2026.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Thu 9/24
7:05 am-12:19 pm
1 stop4h 14m
Indianapolis
Mon 9/28
8:52 pm-12:04 am
1 stop4h 12m
$257
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Mon 9/21
5:56 pm-11:09 pm
1 stop4h 13m
Indianapolis
Tue 9/22
8:52 pm-12:04 am
1 stop4h 12m
$257
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Mon 9/21
3:50 pm-10:40 pm
1 stop5h 50m
Indianapolis
Tue 9/22
12:15 pm-10:00 pm
2 stops10h 45m
$262
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Mon 9/21
3:50 pm-10:40 pm
1 stop5h 50m
Indianapolis
Wed 9/23
12:15 pm-10:00 pm
2 stops10h 45m
$262
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Sat 9/19
5:30 am-9:40 pm
2 stops15h 10m
Indianapolis
Mon 9/21
5:00 pm-10:15 pm
1 stop6h 15m
$268
Quickest round-trip
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Mon 9/21
5:59 pm-11:05 pm
1 stop4h 06m
Indianapolis
Fri 9/25
6:35 am-9:38 am
1 stop4h 03m
$278
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Mon 9/21
5:56 pm-11:09 pm
1 stop4h 13m
Indianapolis
Fri 9/25
8:52 pm-12:04 am
1 stop4h 12m
$278
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Thu 9/17
3:50 pm-10:40 pm
1 stop5h 50m
Indianapolis
Fri 9/18
5:00 pm-10:15 pm
1 stop6h 15m
$278
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Thu 9/24
5:40 am-12:10 pm
1 stop5h 30m
Indianapolis
Mon 9/28
1:15 pm-10:15 pm
2 stops10h 00m
$283
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Mon 11/16
5:29 pm-12:13 am
1 stop5h 44m
Indianapolis
Sun 11/22
6:35 am-10:19 am
1 stop4h 44m
$295
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Indianapolis in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Des Moines with our price prediction graph.
DSM-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Indianapolis
What is the cheapest month to book a flight from Des Moines to Indianapolis?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $298). Flying from Des Moines to Indianapolis in May is currently the most expensive (average of $606). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Indianapolis?
Airfare is below average for this route at the moment.
Des Moines to Indianapolis flights typically cost between $410 and $511 in September.The cheapest round-trip price found within the last 5 days was $250 on Frontier (Sep 21-Sep 23).
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated August 18, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Des Moines to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Food
7.2
Overall
7.8
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Food
7.2
Overall
7.8
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Food
7.2
Overall
7.8
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Food
7.2
Overall
7.8
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Greenwood
Plainfield
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Anderson
Crawfordsville
Carmel
Noblesville
Bloomington
Speedway
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Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 18, 2026.
Des Moines and Indianapolis flights
Browse other Des Moines and Indianapolis flight options. Last updated on August 18, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on August 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Des Moines to Indianapolis
Discover the top 3 airlines that operate flights from Des Moines to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$346 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$254 | Average$311 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$272 | Average$358 | FlexibilityNo cancel fee | On-time69% |