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$164+ Cheap flights from Des Moines to Indianapolis (DSM - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Des Moines to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$237
(Delta)

One-way from

$164
(United Airlines)

Popular in

October

Cheapest in

July

Average price

$272
From Des Moines to Indianapolis
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One-way flight from Des Moines to Indianapolis
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Highest demand for flights based on searches. 8% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Indianapolis

Cheapest flights from Des Moines to Indianapolis
Explore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:05 amDSM - IND
1 stop4h 09mDelta
Tue 11/411:54 amIND - DSM
1 stop5h 58mDelta
Deal found 9/15$237
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/152:37 pmDSM - IND
2 stops22h 14mFrontier
Wed 10/225:24 pmIND - DSM
1 stop21h 28mFrontier
Deal found 9/15$240
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/155:42 pmDSM - IND
1 stop5h 02mAmerican Airlines
Wed 10/223:56 pmIND - DSM
1 stop5h 15mAmerican Airlines
Deal found 9/15$241
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/302:32 pmDSM - IND
1 stop28h 12mMultiple Airlines
Thu 11/61:28 pmIND - DSM
1 stop26h 27mMultiple Airlines
Deal found 9/14$243
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:20 amDSM - IND
2 stops6h 30mSouthwest
Wed 10/225:05 pmIND - DSM
2 stops5h 45mSouthwest
Deal found 9/15$247
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:52 pmDSM - IND
1 stop5h 23mDelta
Tue 11/1110:29 amIND - DSM
1 stop6h 50mDelta
Deal found 9/17$251
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:22 pmDSM - IND
1 stop4h 57mAmerican Airlines
Mon 10/274:32 pmIND - DSM
1 stop4h 39mAmerican Airlines
Deal found 9/17$258
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/317:00 amDSM - IND
1 stop7h 31mAmerican Airlines
Fri 11/75:26 amIND - DSM
1 stop6h 14mAmerican Airlines
Deal found 9/15$270
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/710:21 amDSM - IND
1 stop6h 06mDelta
Tue 12/910:29 amIND - DSM
1 stop6h 47mDelta
Deal found 9/16$282
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:32 pmDSM - IND
1 stop24h 03mMultiple Airlines
Fri 11/710:14 pmIND - DSM
2 stops36h 46mMultiple Airlines
Deal found 9/15$286
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/125:56 pmDSM - IND
1 stop5h 03mDelta
Tue 10/144:25 pmIND - DSM
1 stop5h 38mDelta
Deal found 9/16$292

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.

Fly from

Des Moines

Fly to

Indianapolis

Route

Depart

Return

Price

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 10/29

6:05 am-11:14 am

1 stop4h 09m

Indianapolis

Tue 11/4

11:54 am-4:52 pm

1 stop5h 58m

$237

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 10/15

2:37 pm-1:51 pm

2 stops22h 14m

Indianapolis

Wed 10/22

5:24 pm-1:52 pm

1 stop21h 28m

$240

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 10/15

5:42 pm-11:44 pm

1 stop5h 02m

Indianapolis

Wed 10/22

3:56 pm-8:11 pm

1 stop5h 15m

$241

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 10/30

2:32 pm-7:44 pm

1 stop28h 12m

Indianapolis

Thu 11/6

1:28 pm-2:55 pm

1 stop26h 27m

$243

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 10/15

6:20 am-1:50 pm

2 stops6h 30m

Indianapolis

Wed 10/22

5:05 pm-9:50 pm

2 stops5h 45m

$247

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 11/10

5:52 pm-12:15 am

1 stop5h 23m

Indianapolis

Tue 11/11

10:29 am-4:19 pm

1 stop6h 50m

$251

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 10/25

6:22 pm-12:19 am

1 stop4h 57m

Indianapolis

Mon 10/27

4:32 pm-8:11 pm

1 stop4h 39m

$258

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 10/31

7:00 am-3:31 pm

1 stop7h 31m

Indianapolis

Fri 11/7

5:26 am-10:40 am

1 stop6h 14m

$270

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sun 12/7

10:21 am-5:27 pm

1 stop6h 06m

Indianapolis

Tue 12/9

10:29 am-4:16 pm

1 stop6h 47m

$282

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 10/31

2:32 pm-3:35 pm

1 stop24h 03m

Indianapolis

Fri 11/7

10:14 pm-10:00 am

2 stops36h 46m

$286

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 15 results
1
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Best time to book a flight from Des Moines to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indianapolis

What is the cheapest month to book a flight from Des Moines to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $286). Flying from Des Moines to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IND?

Find hourly flight availability from Des Moines to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from Des Moines to Indianapolis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Indianapolis?

    A quick flight from Des Moines to Indianapolis can take about 4h 09m. Delta provides one of the quickest options available for as low as $237. Des Moines and Indianapolis are separated by a distance of 406 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Indianapolis round-trip?

    Our cheapest airline available from Des Moines to Indianapolis is American Airlines. Our recent data shows that you can find tickets from as low as $196 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $196 and $210 round-trip. You may be able to fly from Des Moines to Indianapolis for 43% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Des Moines to Indianapolis one-way?

    $164 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Southwest and American Airlines, with prices starting from $215 and $254, respectively.

  • Can I find deals for flights from Des Moines to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indianapolis.

  • Can I find deals for business class flights from Des Moines to Indianapolis?

    Yes. Cheapflights offers flight deals from Des Moines to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $286). Flying from Des Moines to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Noblesville
Fishers
Anderson
Kokomo
Greenwood
Bloomington
Franklin
Plainfield
Carmel
Crawfordsville
Speedway

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Alternative routes for Des Moines to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Des Moines to Indianapolis

Discover the top 3 airlines that operate flights from Des Moines to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$310FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$346FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$210Average$403FlexibilityNo cancel feeOn-time69%

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