$102+ Cheap flights from Des Moines to Indianapolis (DSM - IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Indianapolis
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Cheapest flights from Des Moines to IndianapolisExplore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:01 pm -
1 stop5h 56m
Sat 10/316:41 am -
1 stop4h 01m
Deal found 9/16![Delta logo]()
$233
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:35 am -
1 stop5h 20m
Sat 10/3112:10 pm -
2 stops6h 35m
Deal found 9/16![Southwest logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
2 stops34h 04m
Thu 10/2911:25 am -
1 stop22h 00m
Deal found 9/16![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:25 pm -
1 stop17h 43m
Sat 10/311:47 pm -
2 stops26h 12m
Deal found 9/16![Multiple Airlines logo]()
$248
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:50 pm -
1 stop5h 15m
Tue 11/37:00 am -
1 stop4h 11m
Deal found 9/16![Delta logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
2 stops34h 04m
Wed 10/2812:38 pm -
1 stop29h 24m
Deal found 9/17![Multiple Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
2 stops10h 30m
Thu 11/52:55 pm -
1 stop8h 10m
Deal found 9/17![Southwest logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
2 stops34h 04m
Tue 11/311:25 am -
1 stop25h 31m
Deal found 9/17![Multiple Airlines logo]()
$255
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:35 am -
2 stops7h 20m
Thu 10/293:10 pm -
2 stops9h 05m
Deal found 9/14![Southwest logo]()
$260
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:50 pm -
1 stop5h 15m
Wed 10/287:00 am -
1 stop4h 11m
Deal found 9/16![Delta logo]()
$264
Best flights from Des Moines to IndianapolisDiscover carefully curated flight deals from Des Moines to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Des Moines to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:50 pm -
1 stop5h 15m
Wed 10/217:00 am -
1 stop4h 11m
Deal found 9/15![Delta logo]()
$249
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:30 pm -
1 stop6h 45m
Thu 10/293:10 pm -
2 stops9h 05m
Deal found 9/16![Southwest logo]()
$276
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:45 pm -
1 stop4h 02m
Thu 10/2912:46 pm -
1 stop5h 41m
Deal found 9/16![United Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:57 am -
1 stop3h 31m
Tue 11/37:00 am -
1 stop4h 11m
Deal found 9/17![Delta logo]()
$291
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:50 pm -
1 stop5h 15m
Mon 11/27:00 am -
1 stop4h 11m
Deal found 9/17![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:10 am -
2 stops9h 10m
Wed 10/2112:35 pm -
2 stops10h 25m
Deal found 9/15![Southwest logo]()
$341
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:57 am -
1 stop3h 31m
Thu 10/297:00 am -
1 stop4h 11m
Deal found 9/17![Delta logo]()
$291
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:50 pm -
1 stop5h 15m
Mon 10/264:59 pm -
1 stop4h 41m
Deal found 9/17![Delta logo]()
$293
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:50 pm -
1 stop5h 15m
Mon 10/192:57 pm -
1 stop6h 43m
Deal found 9/12![Delta logo]()
$357
Last-minute flights from Des Moines to IndianapolisDiscover last-minute flight deals from Des Moines to Indianapolis. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Indianapolis. Data last updated September 17, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:50 pm -
1 stop5h 15m
Wed 10/287:00 am -
1 stop4h 11m
Deal found 9/16![Delta logo]()
$264
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:01 pm -
1 stop5h 56m
Sat 10/316:41 am -
1 stop4h 01m
Deal found 9/16![Delta logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
2 stops34h 04m
Thu 10/2911:25 am -
1 stop22h 00m
Deal found 9/16![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
2 stops34h 04m
Wed 10/2812:38 pm -
1 stop29h 24m
Deal found 9/17![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
2 stops34h 04m
Tue 11/311:25 am -
1 stop25h 31m
Deal found 9/17![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:25 pm -
1 stop17h 43m
Sat 10/311:47 pm -
2 stops26h 12m
Deal found 9/16![Multiple Airlines logo]()
$248
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:50 pm -
1 stop5h 15m
Tue 11/37:00 am -
1 stop4h 11m
Deal found 9/16![Delta logo]()
$249
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:50 pm -
1 stop5h 15m
Mon 11/212:12 pm -
1 stop5h 43m
Deal found 9/16![Delta logo]()
$265
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:35 am -
1 stop5h 20m
Sat 10/3112:10 pm -
2 stops6h 35m
Deal found 9/16![Southwest logo]()
$238
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:35 am -
2 stops7h 20m
Thu 10/293:10 pm -
2 stops9h 05m
Deal found 9/14![Southwest logo]()
$260
One-way flights from Des Moines to IndianapolisSearch for one-way flight options from Des Moines to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Des Moines to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
2 stops34h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$102
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/161:02 pm -
1 stop6h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$117
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
2 stops9h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Southwest logo]()
$122
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/235:20 am -
2 stops10h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$128
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:45 pm -
1 stop4h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![United Airlines logo]()
$133
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop5h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![United Airlines logo]()
$148
This deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/199:37 am -
1 stop5h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/83:27 pm -
2 stops26h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:04 pm -
3 stops45h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$169
Find flight deals from Des Moines to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $233 (Delta) |
One-way from | $102 (Kiwi.com) |
Popular in | May |
Cheapest in | February |
Average price | $357 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Sat 1/16
12:30 pm-5:24 pm
1 stop3h 54m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$117
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Sat 1/23
7:05 am-3:35 pm
1 stop7h 30m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$117
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Sat 1/16
1:02 pm-8:45 pm
1 stop6h 43m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$117
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Sat 10/24
6:00 am-12:42 pm
1 stop5h 42m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$117
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Wed 12/9
6:00 am-4:50 pm
2 stops9h 50m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$122
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Mon 1/18
6:20 am-2:15 pm
1 stop6h 55m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$133
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Fri 10/9
6:00 am-12:42 pm
1 stop5h 42m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$148
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Sun 10/25
8:00 am-7:04 pm
3 stops34h 04m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$164
Quickest round-trip
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Sun 10/25
7:31 pm-12:19 am
1 stop3h 48m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$179
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Sun 11/8
6:45 pm-11:47 pm
1 stop4h 02m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$179
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Indianapolis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Des Moines with our price prediction graph.
DSM-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Indianapolis
What is the cheapest month to book a flight from Des Moines to Indianapolis?
Currently, February is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $308). Flying from Des Moines to Indianapolis in May is currently the most expensive (average of $606). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Indianapolis?
Airfare is below average for this route at the moment.
Des Moines to Indianapolis flights typically cost between $298 and $486 in October.The cheapest round-trip price found within the last 5 days was $233 on Delta (Oct 24-Oct 31).
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated September 17, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Des Moines to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Greenwood
Plainfield
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Carmel
Noblesville
Bloomington
Speedway
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Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
Des Moines and Indianapolis flights
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Other flights from Des Moines
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Top 3 airlines flying from Des Moines to Indianapolis
Discover the top 3 airlines that operate flights from Des Moines to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$272 | Average$358 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$272 | Average$365 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$276 | Average$367 | FlexibilityNo cancel fee | On-time71% |