HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Indianapolis

$119+ Cheap flights from Des Moines to Indianapolis (DSM - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Indianapolis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 18, 2025.

Round-trip from

$241
(Delta)

One-way from

$119
(American Airlines)

Popular in

November

Cheapest in

July

Average price

$336
From Des Moines to Indianapolis
Search Deals
One-way flight from Des Moines to Indianapolis
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($32 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from Des Moines to Indianapolis

Cheapest flights from Des Moines to Indianapolis
Explore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3010:20 amDSM - IND
1 stop5h 53mDelta
Thu 10/27:00 amIND - DSM
1 stop4h 14mDelta
Deal found 8/16$241
This FlightHub deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/226:20 pmDSM - IND
1 stop20h 20mFrontier
Sun 8/248:59 pmIND - DSM
1 stop18h 24mFrontier
Deal found 8/16$245
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:30 amDSM - IND
1 stop5h 15mSouthwest
Thu 10/26:35 amIND - DSM
2 stops5h 25mSouthwest
Deal found 8/16$246
This Mytrip deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/88:25 amDSM - IND
1 stop10h 48mMultiple Airlines
Wed 9/107:43 pmIND - DSM
2 stops22h 16mMultiple Airlines
Deal found 8/17$248
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:32 pmDSM - IND
1 stop4h 57mDelta
Mon 10/205:00 pmIND - DSM
1 stop4h 35mDelta
Deal found 8/16$276
This Mytrip deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/18:35 amDSM - IND
1 stop8h 26mMultiple Airlines
Fri 9/55:00 amIND - DSM
1 stop10h 40mMultiple Airlines
Deal found 8/17$277
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/38:30 amDSM - IND
1 stop10h 43mMultiple Airlines
Sun 10/512:13 pmIND - DSM
1 stop9h 11mMultiple Airlines
Deal found 8/18$281
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/85:25 pmDSM - IND
1 stop5h 00mDelta
Wed 9/1012:33 pmIND - DSM
1 stop5h 39mDelta
Deal found 8/17$282
This Mytrip deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/28:52 amDSM - IND
1 stop10h 56mMultiple Airlines
Thu 10/98:16 pmIND - DSM
2 stops19h 34mMultiple Airlines
Deal found 8/18$285
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:25 pmDSM - IND
1 stop5h 04mDelta
Thu 10/911:54 amIND - DSM
1 stop5h 58mDelta
Deal found 8/18$286

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.

Fly from

Des Moines

Fly to

Indianapolis

Route

Depart

Return

Price

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 9/30

10:20 am-5:13 pm

1 stop5h 53m

Indianapolis

Thu 10/2

7:00 am-10:14 am

1 stop4h 14m

$241

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 10/3

2:25 pm-4:14 pm

1 stop24h 49m

Indianapolis

Sun 10/5

8:54 pm-1:40 pm

1 stop17h 46m

$241

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 10/29

6:05 am-11:14 am

1 stop4h 09m

Indianapolis

Thu 10/30

7:05 am-10:26 am

1 stop4h 21m

$241

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 10/2

5:25 pm-11:29 pm

1 stop5h 04m

Indianapolis

Thu 10/9

7:05 am-10:26 am

1 stop4h 21m

$245

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 9/30

6:30 am-12:45 pm

1 stop5h 15m

Indianapolis

Thu 10/2

6:35 am-11:00 am

2 stops5h 25m

$246

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 9/8

8:25 am-8:13 pm

1 stop10h 48m

Indianapolis

Wed 9/10

7:43 pm-4:59 pm

2 stops22h 16m

$248

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 10/17

5:32 pm-11:29 pm

1 stop4h 57m

Indianapolis

Mon 10/20

5:00 pm-8:35 pm

1 stop4h 35m

$276

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 9/1

8:35 am-6:01 pm

1 stop8h 26m

Indianapolis

Fri 9/5

5:00 am-2:40 pm

1 stop10h 40m

$277

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 10/3

8:30 am-8:13 pm

1 stop10h 43m

Indianapolis

Sun 10/5

12:13 pm-8:24 pm

1 stop9h 11m

$281

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 9/8

5:25 pm-11:25 pm

1 stop5h 00m

Indianapolis

Wed 9/10

12:33 pm-5:12 pm

1 stop5h 39m

$282

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Showing 1-10 of 22 results
1
2
3

Best time to book a flight from Des Moines to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indianapolis

What is the cheapest month to book a flight from Des Moines to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $297). Flying from Des Moines to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IND?

Find hourly flight availability from Des Moines to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

When flying from Des Moines to Indianapolis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated August 18, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,925 reviews
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Indianapolis?

    A quick flight from Des Moines to Indianapolis can take about 5h 15m. Delta provides one of the quickest options available for as low as $246. Des Moines and Indianapolis are separated by a distance of 406 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Indianapolis round-trip?

    Our cheapest airline available from Des Moines to Indianapolis is American Airlines. Our recent data shows that you can find tickets from as low as $196 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $196 and $210 round-trip. You may be able to fly from Des Moines to Indianapolis for 42% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Des Moines to Indianapolis one-way?

    $119 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and Southwest, with prices starting from $123 and $124, respectively.

  • Can I find deals for flights from Des Moines to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indianapolis.

  • Can I find deals for business class flights from Des Moines to Indianapolis?

    Yes. Cheapflights offers flight deals from Des Moines to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $297). Flying from Des Moines to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Greenwood
Bloomington
Muncie
Noblesville
Fishers
Terre Haute
Anderson
Kokomo
Franklin
Plainfield
Carmel
Crawfordsville
Shelbyville
Speedway

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to O'Hare Intl flights
Des Moines to O'Hare Intl flights
Omaha to Midway flights
Mason City to O'Hare Intl flights
Omaha to Dayton flights
Des Moines to Midway flights
Cedar Rapids to O'Hare Intl flights
Cedar Rapids to Cincinnati flights
Omaha to Louisville flights
Moline to Cincinnati flights
Omaha to Indianapolis flights
Cedar Rapids to Louisville flights
Des Moines to Louisville flights
Omaha to Cincinnati flights
Moline to O'Hare Intl flights
Sioux City to O'Hare Intl flights
Cedar Rapids to Midway flights
Cedar Rapids to Indianapolis flights
Des Moines to Cincinnati flights
Des Moines to Dayton flights
Omaha to Fort Wayne flights
Moline to Dayton flights
Dubuque to O'Hare Intl flights
Waterloo to O'Hare Intl flights
Omaha to South Bend flights
Moline to Louisville flights
La Crosse to O'Hare Intl flights
Des Moines to Rockford flights
La Crosse to Cincinnati flights
Burlington to O'Hare Intl flights
Moline to Midway flights
Sioux City to Louisville flights
Omaha to Kalamazoo flights
Omaha to Evansville flights
Omaha to Rockford flights
Moline to Kalamazoo flights
La Crosse to Louisville flights
La Crosse to Midway flights
La Crosse to Indianapolis flights
La Crosse to Kalamazoo flights
Des Moines to Kalamazoo flights
Cedar Rapids to South Bend flights
La Crosse to Dayton flights
Dubuque to Louisville flights
Dubuque to Cincinnati flights

Top 3 airlines flying from Des Moines to Indianapolis

Discover the top 3 airlines that operate flights from Des Moines to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$307FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$379FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$210Average$403FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.