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$80+ Cheap flights from Des Moines to Indianapolis (DSM - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Jan 4 — Jan 111
Sun 1/4
Sun 1/11
1 adult, Economy
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Cheap flight deals from Des Moines to Indianapolis

Cheapest flights from Des Moines to Indianapolis
Explore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 5, 2025.

This Mytrip deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:47 pmDSM - IND
2 stops18h 46mMultiple Airlines
Wed 12/246:45 amIND - DSM
1 stop14h 42mMultiple Airlines
Deal found 12/5$396
This Kiwi.com deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:15 amDSM - IND
1 stop28h 54mAllegiant Air
Sat 12/1311:00 amIND - DSM
1 stop28h 06mAllegiant Air
Deal found 12/4$402
This Delta deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:17 amDSM - IND
1 stop6h 11mDelta
Mon 12/226:30 amIND - DSM
1 stop4h 19mDelta
Deal found 12/4$407
This Kiwi.com deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:15 amDSM - IND
1 stop28h 54mMultiple Airlines
Sat 12/1312:22 pmIND - DSM
2 stops34h 59mMultiple Airlines
Deal found 12/4$454
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:30 amDSM - IND
1 stop7h 52mUnited Airlines
Tue 12/231:45 pmIND - DSM
1 stop5h 20mUnited Airlines
Deal found 12/4$467
This Mytrip deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:21 pmDSM - IND
1 stop14h 58mAllegiant Air
Tue 12/231:43 pmIND - DSM
1 stop10h 27mAllegiant Air
Deal found 12/4$469
This American Airlines deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/183:55 pmDSM - IND
1 stop4h 02mAmerican Airlines
Tue 12/237:04 pmIND - DSM
1 stop5h 26mAmerican Airlines
Deal found 12/5$488
This Mytrip deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:21 pmDSM - IND
1 stop14h 58mMultiple Airlines
Tue 12/235:15 amIND - DSM
3 stops27h 26mMultiple Airlines
Deal found 12/4$489
This Delta deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:50 amDSM - IND
1 stop4h 17mDelta
Mon 12/156:22 amIND - DSM
1 stop4h 18mDelta
Deal found 12/5$497
This Delta deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/54:59 pmDSM - IND
1 stop6h 24mDelta
Sat 12/64:18 pmIND - DSM
1 stop5h 57mDelta
Deal found 12/5$537

Find flight deals from Des Moines to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 5, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$175
(United Airlines)

One-way from

$80
(United Airlines)

Popular in

June

Cheapest in

September

Average price

$310
Provider with most accurate pricing for Des Moines-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Indianapolis flights.
Search Deals
From Des Moines to Indianapolis
Search Deals
One-way flight from Des Moines to Indianapolis
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 5, 2025.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.

Fly from

Des Moines

Fly to

Indianapolis

Route

Depart

Return

Price

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 2/28

6:49 pm-11:44 pm

1 stop3h 55m

Indianapolis

Tue 3/3

6:00 am-10:53 am

1 stop5h 53m

$175

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 1/13

6:54 am-11:47 am

1 stop3h 53m

Indianapolis

Thu 1/15

7:05 am-10:19 am

1 stop4h 14m

$184

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 2/28

12:25 pm-7:10 pm

1 stop5h 45m

Indianapolis

Mon 3/2

3:42 pm-8:49 pm

1 stop6h 07m

$191

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 1/10

5:58 pm-9:43 am

1 stop14h 45m

Indianapolis

Sun 1/11

8:55 pm-7:22 pm

1 stop23h 27m

$207

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 1/26

6:48 pm-11:30 pm

1 stop3h 42m

Indianapolis

Thu 1/29

11:25 am-2:33 pm

1 stop4h 08m

$251

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 1/13

8:35 am-10:05 pm

2 stops12h 30m

Indianapolis

Thu 1/15

5:05 am-10:50 am

2 stops6h 45m

$255

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 1/12

6:30 am-11:15 pm

1 stop15h 45m

Indianapolis

Thu 1/15

10:38 am-10:09 pm

2 stops12h 31m

$272

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 2/28

5:10 am-3:15 pm

2 stops9h 05m

Indianapolis

Tue 3/3

8:05 am-9:10 pm

2 stops14h 05m

$275

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 2/27

4:21 pm-11:04 pm

1 stop5h 43m

Indianapolis

Sun 3/1

6:15 am-9:55 am

1 stop4h 40m

$279

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 1/13

6:48 pm-11:30 pm

1 stop3h 42m

$80

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/4

Showing 1-10 of 21 results
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Compare providers for flights from Des Moines to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Indianapolis in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Indianapolis flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Des Moines-Indianapolis flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Des Moines-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Indianapolis flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indianapolis

What is the cheapest month to book a flight from Des Moines to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $130). Flying from Des Moines to Indianapolis in May is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IND?

Find hourly flight availability from Des Moines to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 5, 2025.

It’s optimal to fly from Des Moines to Indianapolis in the evening. By choosing this option you can save up to 82% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated December 5, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Food

7.3

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,009 reviews
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Food

7.3

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,065 reviews
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Food

7.3

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,043 reviews
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Food

7.3

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Indianapolis?

    A quick flight from Des Moines to Indianapolis can take about 3h 53m. United Airlines provides one of the quickest options available for as low as $184. Des Moines and Indianapolis are separated by a distance of 406 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Indianapolis round-trip?

    Our cheapest airline available from Des Moines to Indianapolis is Delta. Our recent data shows that you can find tickets from as low as $193 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $196 and $196 round-trip. You may be able to fly from Des Moines to Indianapolis for 39% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Des Moines to Indianapolis one-way?

    $98 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $123 and $125, respectively.

  • Can I find deals for flights from Des Moines to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indianapolis.

  • Can I find deals for business class flights from Des Moines to Indianapolis?

    Yes. Cheapflights offers flight deals from Des Moines to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $130). Flying from Des Moines to Indianapolis in May is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Noblesville
Fishers
Greenwood
Anderson
Kokomo
Plainfield
Franklin
Carmel
Crawfordsville
Bloomington
Speedway

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Alternative routes for Des Moines to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Des Moines to Indianapolis

Discover the top 3 airlines that operate flights from Des Moines to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$308FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$323FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$210Average$386FlexibilityNo cancel feeOn-time69%

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