$137+ Cheap flights from Des Moines to Indianapolis (DSM - IND)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Aug 17 — Aug 241
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Des Moines to IndianapolisExplore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.
Explore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.
This Frontier deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:51 pm
DSM
- IND
1 stop27h 30m
Frontier
Thu 9/178:16 pm
IND
- DSM
1 stop18h 40m
Frontier
Deal found 7/17![Frontier logo]()
$249
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:50 pm
DSM
- IND
1 stop5h 45m
Southwest
Wed 8/197:40 am
IND
- DSM
1 stop5h 10m
Southwest
Deal found 7/14![Southwest logo]()
$273
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:50 pm
DSM
- IND
1 stop5h 45m
Southwest
Thu 8/201:15 pm
IND
- DSM
2 stops9h 55m
Southwest
Deal found 7/16![Southwest logo]()
$278
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am
DSM
- IND
1 stop4h 23m
Delta
Sat 10/314:33 pm
IND
- DSM
1 stop5h 34m
Delta
Deal found 7/17![Delta logo]()
$281
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:00 pm
DSM
- IND
1 stop6h 02m
Delta
Tue 10/206:15 pm
IND
- DSM
1 stop3h 52m
Delta
Deal found 7/17![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:40 am
DSM
- IND
2 stops8h 10m
Southwest
Thu 9/171:15 pm
IND
- DSM
2 stops9h 55m
Southwest
Deal found 7/17![Southwest logo]()
$291
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:10 am
DSM
- IND
2 stops9h 45m
Southwest
Tue 8/185:00 pm
IND
- DSM
1 stop5h 55m
Southwest
Deal found 7/17![Southwest logo]()
$294
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:10 pm
DSM
- IND
2 stops8h 25m
Southwest
Mon 9/281:15 pm
IND
- DSM
2 stops9h 55m
Southwest
Deal found 7/17![Southwest logo]()
$299
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:20 am
DSM
- IND
1 stop4h 08m
Delta
Fri 12/45:49 pm
IND
- DSM
1 stop4h 03m
Delta
Deal found 7/14![Delta logo]()
$310
Best flights from Des Moines to IndianapolisDiscover carefully curated flight deals from Des Moines to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 18, 2026.
Discover carefully curated flight deals from Des Moines to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 18, 2026.
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:20 pm
DSM
- IND
1 stop5h 45m
Delta
Tue 9/16:34 am
IND
- DSM
1 stop4h 09m
Delta
Deal found 7/14![Delta logo]()
$273
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:20 pm
DSM
- IND
1 stop5h 40m
United Airlines
Sat 8/297:00 am
IND
- DSM
1 stop6h 20m
United Airlines
Deal found 7/15![United Airlines logo]()
$273
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:10 am
DSM
- IND
2 stops9h 45m
Southwest
Tue 10/66:50 am
IND
- DSM
1 stop5h 40m
Southwest
Deal found 7/13![Southwest logo]()
$278
This Delta deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
DSM
- IND
1 stop4h 32m
Delta
Thu 8/206:34 am
IND
- DSM
1 stop4h 09m
Delta
Deal found 7/16![Delta logo]()
$273
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:52 pm
DSM
- IND
1 stop3h 49m
United Airlines
Sat 10/311:37 pm
IND
- DSM
1 stop6h 41m
United Airlines
Deal found 7/15![United Airlines logo]()
$273
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:10 am
DSM
- IND
2 stops9h 45m
Southwest
Thu 9/103:05 pm
IND
- DSM
1 stop7h 10m
Southwest
Deal found 7/14![Southwest logo]()
$278
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
DSM
- IND
1 stop6h 39m
Delta
Sat 9/512:12 pm
IND
- DSM
1 stop6h 06m
Delta
Deal found 7/15![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:40 am
DSM
- IND
2 stops12h 15m
Southwest
Wed 8/197:40 am
IND
- DSM
1 stop5h 10m
Southwest
Deal found 7/14![Southwest logo]()
$286
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:40 am
DSM
- IND
2 stops12h 15m
Southwest
Sat 8/296:35 am
IND
- DSM
2 stops13h 50m
Southwest
Deal found 7/15![Southwest logo]()
$289
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
DSM
- IND
1 stop4h 31m
Delta
Sun 9/136:35 am
IND
- DSM
1 stop3h 58m
Delta
Deal found 7/15![Delta logo]()
$310
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:50 am
DSM
- IND
1 stop5h 35m
Southwest
Tue 10/204:05 pm
IND
- DSM
2 stops6h 50m
Southwest
Deal found 7/17![Southwest logo]()
$294
Last-minute flights from Des Moines to IndianapolisDiscover last-minute flight deals from Des Moines to Indianapolis. Data last updated July 18, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Indianapolis. Data last updated July 18, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:15 am
DSM
- IND
1 stop7h 25m
Southwest
Tue 8/185:00 pm
IND
- DSM
1 stop5h 55m
Southwest
Deal found 7/17![Southwest logo]()
$289
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:50 pm
DSM
- IND
1 stop5h 45m
Southwest
Thu 8/201:15 pm
IND
- DSM
2 stops9h 55m
Southwest
Deal found 7/16![Southwest logo]()
$278
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:20 pm
DSM
- IND
1 stop5h 40m
United Airlines
Sun 8/168:00 am
IND
- DSM
1 stop5h 20m
United Airlines
Deal found 7/15![United Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:30 am
DSM
- IND
1 stop5h 40m
Southwest
Sun 8/1611:05 am
IND
- DSM
2 stops12h 45m
Southwest
Deal found 7/15![Southwest logo]()
$321
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:50 pm
DSM
- IND
1 stop5h 45m
Southwest
Wed 8/197:40 am
IND
- DSM
1 stop5h 10m
Southwest
Deal found 7/14![Southwest logo]()
$273
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:30 am
DSM
- IND
2 stops6h 55m
Southwest
Sat 9/56:35 am
IND
- DSM
2 stops13h 50m
Southwest
Deal found 7/15![Southwest logo]()
$324
One-way flights from Des Moines to IndianapolisSearch for one-way flight options from Des Moines to Indianapolis. Find affordable one-way fares based on user searches. Data last updated July 18, 2026.
Search for one-way flight options from Des Moines to Indianapolis. Find affordable one-way fares based on user searches. Data last updated July 18, 2026.
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:00 am
DSM
- IND
1 stop3h 35m
Delta
Deal found 7/13![Delta logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:43 am
DSM
- IND
2 stops26h 01m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$141
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:40 am
DSM
- IND
2 stops12h 15m
Southwest
Deal found 7/14![Southwest logo]()
$142
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
DSM
- IND
1 stop4h 32m
Delta
Deal found 7/18![Delta logo]()
$145
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:24 am
DSM
- IND
1 stop3h 33m
United Airlines
Deal found 7/16![United Airlines logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:12 pm
DSM
- IND
3 stops17h 13m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$175
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
DSM
- IND
2 stops12h 02m
United Airlines
Deal found 7/14![United Airlines logo]()
$177
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:40 am
DSM
- IND
2 stops12h 15m
Southwest
Deal found 7/16![Southwest logo]()
$179
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:00 am
DSM
- IND
1 stop4h 32m
Delta
Deal found 7/17![Delta logo]()
$194
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:40 am
DSM
- IND
2 stops8h 10m
Southwest
Deal found 7/17![Southwest logo]()
$199
Find flight deals from Des Moines to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $249 (Frontier) |
One-way from | $137 (Delta) |
Popular in | May |
Cheapest in | September |
Average price | $319 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Mon 8/31
4:20 pm-11:05 pm
1 stop5h 45m
Indianapolis
Tue 9/1
6:34 am-9:43 am
1 stop4h 09m
$273
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Thu 8/27
3:20 pm-10:00 pm
1 stop5h 40m
Indianapolis
Sat 8/29
7:00 am-12:20 pm
1 stop6h 20m
$273
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Thu 8/13
6:00 am-11:32 am
1 stop4h 32m
Indianapolis
Thu 8/20
6:34 am-9:43 am
1 stop4h 09m
$273
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Fri 10/30
6:52 pm-11:41 pm
1 stop3h 49m
Indianapolis
Sat 10/31
1:37 pm-7:18 pm
1 stop6h 41m
$273
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Sat 8/29
6:00 am-1:39 pm
1 stop6h 39m
Indianapolis
Sat 9/5
12:12 pm-5:18 pm
1 stop6h 06m
$273
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Wed 9/30
6:10 am-4:55 pm
2 stops9h 45m
Indianapolis
Tue 10/6
6:50 am-11:30 am
1 stop5h 40m
$278
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Wed 9/9
6:10 am-4:55 pm
2 stops9h 45m
Indianapolis
Thu 9/10
3:05 pm-9:15 pm
1 stop7h 10m
$278
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Mon 8/17
5:40 am-6:55 pm
2 stops12h 15m
Indianapolis
Wed 8/19
7:40 am-11:50 am
1 stop5h 10m
$286
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Thu 8/27
5:40 am-6:55 pm
2 stops12h 15m
Indianapolis
Sat 8/29
6:35 am-7:25 pm
2 stops13h 50m
$289
Des MoinesIndianapolis
DSM - IND
DSMIND
Des Moines
Sat 10/17
5:50 am-12:25 pm
1 stop5h 35m
Indianapolis
Tue 10/20
4:05 pm-9:55 pm
2 stops6h 50m
$294
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Indianapolis in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Des Moines with our price prediction graph.
DSM-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Indianapolis
What is the cheapest month to book a flight from Des Moines to Indianapolis?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $248). Flying from Des Moines to Indianapolis in May is currently the most expensive (average of $606). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Indianapolis?
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated July 18, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Des Moines to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Muncie
Greenwood
Fishers
Kokomo
Plainfield
Franklin
Mooresville
Anderson
Crawfordsville
Carmel
Noblesville
Bloomington
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Find flights from Des Moines to Indianapolis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 18, 2026.
Des Moines and Indianapolis flights
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Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on July 18, 2026.
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Top 3 airlines flying from Des Moines to Indianapolis
Discover the top 3 airlines that operate flights from Des Moines to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$196 | Average$344 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$196 | Average$298 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$269 | Average$358 | FlexibilityNo cancel fee | On-time69% |