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$176+ Cheap flights from Des Moines to Indianapolis (DSM - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Find flight deals from Des Moines to Indianapolis

Cheapest flights from Des Moines to Indianapolis
Explore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/211:01 amDSM - IND
1 stop3h 28mDelta
Sat 12/66:45 amIND - DSM
1 stop4h 36mDelta
Deal found 11/18$251
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:43 pmDSM - IND
1 stop5h 29mDelta
Mon 12/226:30 amIND - DSM
1 stop4h 19mDelta
Deal found 11/19$277
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:30 amDSM - IND
2 stops26h 29mMultiple Airlines
Thu 12/188:30 amIND - DSM
1 stop6h 36mMultiple Airlines
Deal found 11/19$288
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/183:55 pmDSM - IND
1 stop5h 57mAmerican Airlines
Tue 12/238:11 pmIND - DSM
1 stop5h 26mAmerican Airlines
Deal found 11/19$292
This Southwest deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:15 amDSM - IND
2 stops9h 45mSouthwest
Thu 12/182:55 pmIND - DSM
2 stops9h 40mSouthwest
Deal found 11/19$293
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/201:24 pmDSM - IND
1 stop7h 05mAmerican Airlines
Sun 12/218:11 pmIND - DSM
1 stop5h 26mAmerican Airlines
Deal found 11/20$347
This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:17 amDSM - IND
1 stop4h 12mDelta
Sun 12/146:22 amIND - DSM
1 stop4h 18mDelta
Deal found 11/20$373
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/297:30 amDSM - IND
1 stop14h 58mMultiple Airlines
Wed 12/37:00 amIND - DSM
2 stops39h 36mMultiple Airlines
Deal found 11/19$374
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:50 amDSM - IND
1 stop4h 12mDelta
Tue 12/212:09 pmIND - DSM
1 stop5h 07mDelta
Deal found 11/18$404
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:17 amDSM - IND
1 stop6h 11mDelta
Mon 12/86:45 amIND - DSM
1 stop4h 36mDelta
Deal found 11/19$407

Cheap flight deals from Des Moines to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$231
(Delta)

One-way from

$176
(Kiwi.com)

Popular in

June

Cheapest in

September

Average price

$386
Provider with most accurate pricing for Des Moines-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Indianapolis flights.
Search Deals
From Des Moines to Indianapolis
Search Deals
One-way flight from Des Moines to Indianapolis
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.

Fly from

Des Moines

Fly to

Indianapolis

Route

Depart

Return

Price

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 2/19

6:19 am-11:28 am

1 stop4h 09m

Indianapolis

Sat 2/21

6:15 am-10:11 am

1 stop4h 56m

$231

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 12/10

6:50 am-12:07 pm

1 stop4h 17m

Indianapolis

Wed 12/10

4:28 pm-9:15 pm

1 stop5h 47m

$251

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 12/2

11:01 am-3:29 pm

1 stop3h 28m

Indianapolis

Sat 12/6

6:45 am-10:21 am

1 stop4h 36m

$251

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 12/11

7:15 am-1:09 pm

1 stop28h 54m

Indianapolis

Thu 12/18

8:30 am-2:06 pm

1 stop6h 36m

$277

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 12/18

5:43 pm-12:12 am

1 stop5h 29m

Indianapolis

Mon 12/22

6:30 am-9:49 am

1 stop4h 19m

$277

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 12/11

8:30 am-11:59 am

2 stops26h 29m

Indianapolis

Thu 12/18

8:30 am-2:06 pm

1 stop6h 36m

$288

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 12/18

3:55 pm-10:52 pm

1 stop5h 57m

Indianapolis

Tue 12/23

8:11 pm-12:37 am

1 stop5h 26m

$292

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 11/26

3:49 pm-6:21 pm

1 stop25h 32m

$176

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sun 11/30

8:51 am-4:15 pm

1 stop6h 24m

$249

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 12/2

6:17 am-11:29 am

1 stop4h 12m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/17

Showing 1-10 of 16 results
1
2

Compare providers for flights from Des Moines to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Indianapolis in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Indianapolis flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Des Moines-Indianapolis flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Des Moines-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Indianapolis flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indianapolis

What is the cheapest month to book a flight from Des Moines to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $130). Flying from Des Moines to Indianapolis in May is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IND?

Find hourly flight availability from Des Moines to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

It’s optimal to fly from Des Moines to Indianapolis in the evening. By choosing this option you can save up to 82% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated November 20, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,029 reviews
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Indianapolis?

    A quick flight from Des Moines to Indianapolis can take about 4h 09m. Delta provides one of the quickest options available for as low as $231. Des Moines and Indianapolis are separated by a distance of 406 mi.

  • What are the cheapest airlines flying from Des Moines to Indianapolis round-trip?

    Our cheapest airline available from Des Moines to Indianapolis is American Airlines. Our recent data shows that you can find tickets from as low as $196 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $196 and $210 round-trip. You may be able to fly from Des Moines to Indianapolis for 39% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Des Moines to Indianapolis one-way?

    $176 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $249 and $249, respectively.

  • Can I find deals for flights from Des Moines to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indianapolis.

  • Can I find deals for business class flights from Des Moines to Indianapolis?

    Yes. Cheapflights offers flight deals from Des Moines to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $130). Flying from Des Moines to Indianapolis in May is currently the most expensive (average of $299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Noblesville
Fishers
Greenwood
Anderson
Kokomo
Bloomington
Plainfield
Franklin
Carmel
Crawfordsville
Speedway

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Top 3 airlines flying from Des Moines to Indianapolis

Discover the top 3 airlines that operate flights from Des Moines to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$308FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$327FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$210Average$386FlexibilityNo cancel feeOn-time69%

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