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$126+ Cheap flights from Des Moines to Indianapolis (DSM - IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Mar 28 — Apr 41
Sat 3/28
Sat 4/4
1 adult, Economy
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Cheap flight deals from Des Moines to Indianapolis

Cheapest flights from Des Moines to Indianapolis
Explore the most affordable flight options available from Des Moines to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 26, 2026.

This Frontier deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:14 pm
DSM
-
IND
1 stop22h 18m
Frontier
Thu 4/168:46 pm
IND
-
DSM
1 stop17h 23m
Frontier
Deal found 2/24$182
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:51 am
DSM
-
IND
1 stop3h 51m
Delta
Wed 4/112:19 pm
IND
-
DSM
1 stop5h 35m
Delta
Deal found 2/25$251
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
DSM
-
IND
1 stop6h 10m
American Airlines
Sat 4/188:53 pm
IND
-
DSM
1 stop3h 56m
American Airlines
Deal found 2/25$254
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/31:10 pm
DSM
-
IND
1 stop4h 42m
United Airlines
Tue 4/77:52 pm
IND
-
DSM
1 stop4h 10m
United Airlines
Deal found 2/24$260
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:49 pm
DSM
-
IND
1 stop3h 37m
United Airlines
Fri 3/2711:04 am
IND
-
DSM
1 stop4h 20m
United Airlines
Deal found 2/23$264
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:25 pm
DSM
-
IND
1 stop6h 22m
Delta
Sat 3/286:13 am
IND
-
DSM
1 stop4h 46m
Delta
Deal found 2/26$267
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/262:04 pm
DSM
-
IND
1 stop3h 46m
United Airlines
Thu 4/27:52 pm
IND
-
DSM
1 stop4h 10m
United Airlines
Deal found 2/24$277
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:00 am
DSM
-
IND
2 stops27h 23m
Multiple Airlines
Sun 4/198:46 pm
IND
-
DSM
1 stop17h 23m
Multiple Airlines
Deal found 2/26$283
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:04 pm
DSM
-
IND
1 stop4h 30m
Delta
Sun 5/107:02 am
IND
-
DSM
1 stop4h 14m
Delta
Deal found 2/25$299
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:16 pm
DSM
-
IND
1 stop9h 16m
American Airlines
Sun 5/108:53 pm
IND
-
DSM
1 stop3h 56m
American Airlines
Deal found 2/25$306
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:23 am
DSM
-
IND
1 stop4h 07m
United Airlines
Tue 6/163:16 pm
IND
-
DSM
1 stop5h 09m
United Airlines
Deal found 2/22$307

Find flight deals from Des Moines to Indianapolis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$182
(Frontier)

One-way from

$126
(United Airlines)

Popular in

November

Cheapest in

September

Average price

$308
Provider with most accurate pricing for Des Moines-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Indianapolis flights.
Search Deals
From Des Moines to Indianapolis
Search Deals
One-way flight from Des Moines to Indianapolis
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 26, 2026.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 4/8

5:47 pm-12:02 am

1 stop5h 15m

Indianapolis

Wed 4/15

2:08 pm-5:02 pm

1 stop3h 54m

$251

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 3/26

4:25 pm-11:47 pm

1 stop6h 22m

Indianapolis

Sat 3/28

6:13 am-9:59 am

1 stop4h 46m

$267

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 3/23

2:04 pm-8:05 pm

1 stop5h 01m

Indianapolis

Mon 3/30

6:05 pm-9:27 pm

1 stop4h 22m

$277

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 4/8

5:30 am-12:05 pm

1 stop5h 35m

Indianapolis

Wed 4/15

3:40 pm-10:10 pm

2 stops7h 30m

$299

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 5/7

1:04 pm-6:34 pm

1 stop4h 30m

Indianapolis

Sun 5/10

6:30 am-9:46 am

1 stop4h 16m

$302

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 5/8

11:09 am-8:13 pm

1 stop8h 04m

Indianapolis

Sun 5/10

7:43 pm-11:49 pm

1 stop5h 06m

$315

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 6/9

6:25 am-12:45 pm

1 stop5h 20m

Indianapolis

Tue 6/16

12:30 pm-10:45 pm

2 stops11h 15m

$322

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 6/6

6:10 am-12:25 pm

1 stop5h 15m

Indianapolis

Tue 6/9

12:30 pm-10:45 pm

2 stops11h 15m

$322

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 5/8

5:28 pm-11:12 pm

1 stop4h 44m

Indianapolis

Sun 5/10

6:30 am-9:46 am

1 stop4h 16m

$327

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sun 5/17

5:20 am-12:15 pm

1 stop5h 55m

Indianapolis

Mon 5/18

6:50 am-11:45 am

1 stop5h 55m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/25

Showing 1-10 of 22 resultsSorted by cheapest first
1
2
3

Compare providers for flights from Des Moines to Indianapolis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Indianapolis in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Indianapolis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indianapolis

What is the cheapest month to book a flight from Des Moines to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $130). Flying from Des Moines to Indianapolis in January is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated February 26, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Indianapolis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,237 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,237 reviews
Delta
7.9
Good
8,237 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,348 reviews
Delta
7.9
Good
8,237 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,352 reviews
Delta
7.9
Good
8,237 reviews

Overall

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Indianapolis?

    A quick flight from Des Moines to Indianapolis can take about 5h 01m. Delta provides one of the quickest options available for as low as $277. Des Moines and Indianapolis are separated by a distance of 406 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Indianapolis round-trip?

    Our cheapest airline available from Des Moines to Indianapolis is American Airlines. Our recent data shows that you can find tickets from as low as $196 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $196 and $210 round-trip. You may be able to fly from Des Moines to Indianapolis for 39% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Des Moines to Indianapolis one-way?

    $98 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $123 and $125, respectively.

  • Can I find deals for flights from Des Moines to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indianapolis.

  • Can I find deals for business class flights from Des Moines to Indianapolis?

    Yes. Cheapflights offers flight deals from Des Moines to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Des Moines to Indianapolis (average of $130). Flying from Des Moines to Indianapolis in January is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Noblesville
Greenwood
Plainfield
Kokomo
Mooresville
Franklin
Anderson
Carmel
Crawfordsville
Bloomington

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Des Moines to Indianapolis

Discover the top 3 airlines that operate flights from Des Moines to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$310FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$311FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$210Average$366FlexibilityNo cancel feeOn-time69%

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