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South Carolina

$30+ Cheap flights from Indiana to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
IND — CHS
ene. 7 — ene. 141
mié. 1/7
mié. 1/14
1 adult, Economy
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Cheap flight deals from Indiana to South Carolina

Cheapest flights from Indiana to South Carolina
Explore the most affordable flight options available from Indiana to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 8, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/255:25 amORD - CLT
Nonstop2h 07mFrontier
jue. 1/19:27 amCLT - ORD
Nonstop2h 13mFrontier
Deal found 12/8$77
This Frontier deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/255:25 amORD - CLT
Nonstop2h 07mFrontier
lun. 12/299:43 pmCLT - ORD
1 stop12h 19mFrontier
Deal found 12/7$120
This Super.com deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/195:45 amORD - CLT
Nonstop2h 07mFrontier
dom. 1/113:45 pmCLT - ORD
Nonstop2h 22mFrontier
Deal found 12/6$121
This Super.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/265:45 amORD - CLT
Nonstop2h 07mFrontier
jue. 1/19:27 amCLT - ORD
Nonstop2h 13mFrontier
Deal found 12/7$127
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/255:25 amORD - CLT
Nonstop2h 07mFrontier
mar. 12/309:24 pmCLT - ORD
1 stop13h 54mFrontier
Deal found 12/7$133
This Frontier deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/255:25 amORD - CLT
Nonstop2h 07mFrontier
vie. 1/29:47 amCLT - ORD
Nonstop2h 13mFrontier
Deal found 12/7$134
This Kiwi.com deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/185:25 amORD - CLT
Nonstop2h 07mMultiple Airlines
sáb. 1/105:38 pmCLT - ORD
1 stop16h 34mMultiple Airlines
Deal found 12/6$138
This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/256:05 pmORD - CLT
Nonstop2h 15mUnited Airlines
jue. 1/111:02 amCLT - ORD
Nonstop2h 28mUnited Airlines
Deal found 12/6$139
This Frontier deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/185:25 amORD - CLT
Nonstop2h 07mFrontier
lun. 12/229:43 pmCLT - ORD
1 stop12h 19mFrontier
Deal found 12/7$145
This Frontier deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/185:25 amORD - CLT
Nonstop2h 07mFrontier
dom. 12/219:33 pmCLT - ORD
1 stop12h 14mFrontier
Deal found 12/7$146
This CheapOair deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/132:59 pmMDW - CLT
1 stop20h 42mFrontier
dom. 12/219:33 pmCLT - MDW
1 stop25h 25mFrontier
Deal found 12/6$185
This CheapOair deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/132:59 pmMDW - CLT
1 stop20h 42mFrontier
lun. 12/1510:32 amCLT - MDW
1 stop12h 26mFrontier
Deal found 12/5$205

Find flight deals from Indiana to South Carolina

Keep the following information in mind while searching for Indiana to South Carolina flight deals. Data was last updated diciembre 8, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$67
(Kiwi.com)

One-way from

$30
(Frontier)

Popular in

December

Cheapest in

August

Average price

$421

Good round-trip deal

$194 or less
Provider with most accurate pricing for Indianapolis-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Myrtle Beach Intl flights.
Search Deals
From Indiana to South Carolina
Search Deals
One-way flight from Indiana to South Carolina
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($55 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Indiana to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 8, 2025.
Use the filters below to find and compare flights from Indiana to South Carolina that are best for you.

Fly from

Indiana

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

mié. 1/14

7:17 am-10:33 am

Nonstop2h 16m

Charlotte Douglas

mié. 1/21

10:44 am-12:12 pm

Nonstop2h 28m

$139

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

dom. 1/18

2:18 pm-5:24 pm

Nonstop2h 06m

Charlotte Douglas

mié. 1/21

6:10 am-7:43 am

Nonstop2h 33m

$139

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

jue. 1/15

6:00 pm-8:50 pm

Nonstop1h 50m

Charlotte Douglas

dom. 1/18

5:50 pm-6:55 pm

Nonstop2h 05m

$158

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

jue. 2/5

7:17 am-10:33 am

Nonstop2h 16m

Charlotte Douglas

sáb. 2/7

6:10 am-7:43 am

Nonstop2h 33m

$158

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

sáb. 1/24

7:17 am-10:33 am

Nonstop2h 16m

Charlotte Douglas

lun. 1/26

6:10 am-7:43 am

Nonstop2h 33m

$158

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

vie. 1/16

6:15 pm-9:37 pm

Nonstop2h 22m

Charlotte Douglas

sáb. 1/17

6:10 am-7:43 am

Nonstop2h 33m

$158

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

vie. 2/27

6:10 pm-9:21 pm

Nonstop2h 11m

Charlotte Douglas

sáb. 2/28

6:00 am-7:26 am

Nonstop2h 26m

$169

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

lun. 1/12

4:38 pm-2:42 pm

1 stop21h 04m

Myrtle Beach Intl

lun. 1/26

10:00 am-10:42 pm

1 stop13h 42m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

mié. 1/14

6:45 am-1:38 pm

1 stop5h 53m

Charlotte Douglas

mié. 1/21

6:00 am-8:52 am

1 stop3h 52m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

jue. 1/29

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

dom. 2/1

5:50 am-6:55 am

Nonstop2h 05m

$177

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/7

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to South Carolina

What is the cheapest month to book a flight from Indiana to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Indiana to South Carolina (average of $47). Flying from Indiana to South Carolina in December is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SC?

Find hourly flight availability from Indiana to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 8, 2025.

One of the essential ways to save on airfare from Indiana to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 13% on airfare.

What is the cheapest day to fly from Indiana to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Indiana to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Indiana to South Carolina flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated diciembre 8, 2025.
Read through reviews of airlines operating flights from Indiana to South Carolina, such as Delta, United Airlines, and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Entertainment

7.9

Comfort

7.9

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Entertainment

7.9

Comfort

7.9

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,084 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Entertainment

7.9

Comfort

7.9

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,044 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Entertainment

7.9

Comfort

7.9

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Allegiant Air
7.2
Good
698 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Entertainment

7.9

Comfort

7.9

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,168 reviews
Delta
7.9
Good
8,011 reviews

Boarding

8.1

Entertainment

7.9

Comfort

7.9

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Indiana to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Indiana to South Carolina flight route?

    This flight path from Indiana to South Carolina was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Indiana to South Carolina?

    Airlines like United Airlines, Southwest, and Spirit Airlines fly from Indiana to South Carolina in about 1h 50m. The time it takes to get you to your destination can typically vary by up to 19h 14m. Indiana and South Carolina are separated by a distance of 583 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Indiana to South Carolina one-way?

    $40 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Spirit Airlines and American Airlines, with prices starting from $76 and $79, respectively.

  • Can I find deals for flights from Indiana to South Carolina that include hotel bookings?

    Yes. In addition to deals on Indiana to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to South Carolina.

  • Can I find deals for business class flights from Indiana to South Carolina?

    Yes. Cheapflights offers flight deals from Indiana to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Indiana to South Carolina (average of $47). Flying from Indiana to South Carolina in December is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Indiana to South Carolina

Discover the top 6 airlines that operate flights from Indiana to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$76Average$118FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$128Average$209FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$166Average$390FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$343FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$198Average$342FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$247Average$412FlexibilityNo cancel feeOn-time63%

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