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South Carolina

$51+ Cheap flights from Indiana to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel.
IND — CHS
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Indiana to South Carolina

Keep the following information in mind while searching for Indiana to South Carolina flight deals. Data was last updated junio 12, 2025.

Round-trip from

$117
(Kiwi.com)

One-way from

$51
(FlightHub)

Popular in

December

Cheapest in

September

Average price

$316

Good round-trip deal

$87 or less

Good one-way deal

$69 or less
From Indiana to South Carolina
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One-way flight from Indiana to South Carolina
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Highest demand for flights based on searches. 12% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Price to beat on a round-trip flight from Indiana to South Carolina.
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Price to beat on a one-way flight from Indiana to South Carolina.
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Find flight deals from Indiana to South Carolina

Cheapest flights from Indiana to South Carolina
Explore the most affordable flight options available from Indiana to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/301:34 pmORD - MYR
Nonstop2h 02mSpirit Airlines
jue. 7/103:16 pmMYR - ORD
Nonstop2h 25mSpirit Airlines
Deal found 6/12$117
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/306:10 pmMDW - MYR
Nonstop2h 05mSouthwest
mar. 10/77:10 amMYR - MDW
Nonstop2h 10mSouthwest
Deal found 6/11$157
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/158:26 amORD - SAV
Nonstop2h 11mAmerican Airlines
mar. 8/1912:29 pmSAV - ORD
Nonstop2h 31mAmerican Airlines
Deal found 6/11$157
This FlightHub deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/135:05 amORD - CAE
1 stop7h 16mSpirit Airlines
sáb. 9/202:16 pmCAE - ORD
1 stop7h 24mSpirit Airlines
Deal found 6/12$163
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/17:10 amORD - SAV
Nonstop2h 25mUnited Airlines
lun. 8/47:07 pmSAV - ORD
1 stop5h 23mUnited Airlines
Deal found 6/10$167
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/1511:20 amORD - MYR
Nonstop2h 15mUnited Airlines
lun. 8/184:50 pmMYR - ORD
Nonstop2h 30mUnited Airlines
Deal found 6/12$177
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/286:35 pmMDW - CLT
Nonstop1h 55mSouthwest
lun. 9/16:00 amCLT - MDW
Nonstop1h 55mSouthwest
Deal found 6/10$177
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/296:16 pmORD - CLT
Nonstop2h 21mUnited Airlines
dom. 8/316:40 amCLT - ORD
Nonstop2h 20mUnited Airlines
Deal found 6/10$177
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/11:50 pmORD - SAV
1 stop7h 35mSouthwest
lun. 8/411:25 amSAV - ORD
1 stop6h 00mSouthwest
Deal found 6/10$177
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/2612:36 pmORD - CLT
Nonstop2h 04mAmerican Airlines
vie. 8/2910:32 pmCLT - ORD
Nonstop2h 10mAmerican Airlines
Deal found 6/10$178
This Cheapflightsfares deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/101:08 pmORD - CLT
Nonstop2h 08mFrontier
lun. 10/138:49 pmCLT - ORD
Nonstop2h 18mFrontier
Deal found 6/11$181
This Cheapflightsfares deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/265:05 amORD - CLT
1 stop10h 18mSpirit Airlines
sáb. 6/289:04 amCLT - ORD
1 stop9h 40mSpirit Airlines
Deal found 6/10$190

Cheapflights Fare Finder

Customize your flight search to find flights from Indiana to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Indiana to South Carolina that are best for you.

Fly from

Indiana

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

lun. 6/30

1:34 pm-4:36 pm

Nonstop2h 02m

Myrtle Beach Intl

jue. 7/10

3:16 pm-4:41 pm

Nonstop2h 25m

$117

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

vie. 8/15

8:26 am-11:37 am

Nonstop2h 11m

Savannah/Hilton Head

mar. 8/19

12:29 pm-2:00 pm

Nonstop2h 31m

$157

ChicagoMyrtle Beach

MDW - MYR

MDWMYR

Chicago Midway

sáb. 8/2

3:05 pm-6:05 pm

Nonstop2h 00m

Myrtle Beach Intl

mié. 8/6

6:30 am-7:40 am

Nonstop2h 10m

$167

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

vie. 8/1

7:10 am-10:35 am

Nonstop2h 25m

Savannah/Hilton Head

lun. 8/4

7:07 pm-11:30 pm

1 stop5h 23m

$167

ChicagoColumbia

ORD - CAE

ORDCAE

Chicago O'Hare Intl

lun. 7/7

5:05 am-4:46 pm

1 stop10h 41m

Columbia Metropolitan

sáb. 7/12

4:37 pm-11:53 pm

1 stop8h 16m

$175

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

vie. 8/15

11:20 am-2:35 pm

Nonstop2h 15m

Myrtle Beach Intl

lun. 8/18

4:50 pm-6:20 pm

Nonstop2h 30m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

jue. 8/28

6:35 pm-9:30 pm

Nonstop1h 55m

Charlotte Douglas

lun. 9/1

6:00 am-6:55 am

Nonstop1h 55m

$177

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

vie. 8/29

6:16 pm-9:37 pm

Nonstop2h 21m

Charlotte Douglas

dom. 8/31

6:40 am-8:00 am

Nonstop2h 20m

$177

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

vie. 8/1

1:50 pm-10:25 pm

1 stop7h 35m

Savannah/Hilton Head

lun. 8/4

11:25 am-4:25 pm

1 stop6h 00m

$177

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

mar. 8/26

12:36 pm-3:40 pm

Nonstop2h 04m

Charlotte Douglas

vie. 8/29

10:32 pm-11:42 pm

Nonstop2h 10m

$178

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to South Carolina

What is the cheapest month to book a flight from Indiana to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Indiana to South Carolina (average of $217). Flying from Indiana to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SC?

Find hourly flight availability from Indiana to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

When flying from Indiana to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated junio 12, 2025.
Read through reviews of airlines operating flights from Indiana to South Carolina, such as Alaska Airlines, Southwest and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Crew

8.5

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Crew

8.5

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,287 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Crew

8.5

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,950 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Crew

8.5

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Crew

8.5

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
JetBlue
7.3
Good
2,925 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Crew

8.5

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Indiana to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Indiana to South Carolina flight route?

    This flight path from Indiana to South Carolina was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Indiana to South Carolina one-way?

    $51 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Southwest and United Airlines, with prices starting from $79 and $79, respectively.

  • Can I find deals for flights from Indiana to South Carolina that include hotel bookings?

    Yes. In addition to deals on Indiana to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to South Carolina.

  • Can I find deals for business class flights from Indiana to South Carolina?

    Yes. Cheapflights offers flight deals from Indiana to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Indiana to South Carolina (average of $217). Flying from Indiana to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Indiana to South Carolina

Discover the top 6 airlines that operate flights from Indiana to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$81Average$129FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$114Average$208FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$198Average$394FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$336FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$228Average$368FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$276Average$373FlexibilityNo cancel feeOn-time63%

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