$45+ Cheap flights from Indiana to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/7. Fares are subject to change and may not be available on all flights or dates of travel.
IND — CHS
Jul 8 — Jul 151
Round-trip
1 adult, Economy
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Find cheap flights from Indiana to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Indiana to South Carolina
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Cheapest flights from Indiana to South CarolinaExplore the most affordable flight options available from Indiana to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
Explore the most affordable flight options available from Indiana to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:42 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Fri 7/176:00 am
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$100
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:46 am
CVG
- SAV
Nonstop1h 35m
Allegiant Air
Mon 6/296:00 am
SAV
- CVG
Nonstop1h 41m
Allegiant Air
Deal found 6/3![Allegiant Air logo]()
$101
This CheapOair deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:43 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Sat 7/259:09 pm
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$103
This CheapOair deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:42 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Mon 7/136:00 am
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 6/5![Allegiant Air logo]()
$104
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/171:40 pm
CVG
- MYR
Nonstop1h 32m
Allegiant Air
Mon 7/209:30 pm
MYR
- CVG
Nonstop1h 37m
Allegiant Air
Deal found 6/3![Allegiant Air logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:42 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Thu 7/166:12 pm
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$105
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/262:05 pm
CVG
- MYR
Nonstop1h 30m
Allegiant Air
Sat 7/49:53 pm
MYR
- CVG
Nonstop1h 37m
Allegiant Air
Deal found 6/3![Allegiant Air logo]()
$106
This CheapOair deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:42 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Mon 7/206:00 am
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:43 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Fri 7/176:00 am
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$107
This Cheapflightsfares deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:36 pm
CVG
- MYR
Nonstop1h 32m
Allegiant Air
Sat 8/19:58 pm
MYR
- CVG
Nonstop1h 37m
Allegiant Air
Deal found 6/5![Allegiant Air logo]()
$108
This Cheapflightsfares deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:37 pm
CVG
- MYR
Nonstop1h 32m
Allegiant Air
Mon 6/159:47 pm
MYR
- CVG
Nonstop1h 37m
Allegiant Air
Deal found 6/5![Allegiant Air logo]()
$109
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:10 pm
CVG
- MYR
Nonstop1h 30m
Allegiant Air
Mon 6/159:47 pm
MYR
- CVG
Nonstop1h 37m
Allegiant Air
Deal found 6/3![Allegiant Air logo]()
$110
Best flights from Indiana to South CarolinaDiscover carefully curated flight deals from Indiana to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
Discover carefully curated flight deals from Indiana to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:29 am
ORD
- CLT
Nonstop2h 14m
United Airlines
Wed 7/158:05 am
CLT
- ORD
Nonstop2h 17m
United Airlines
Deal found 6/5![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:05 pm
MDW
- MYR
Nonstop2h 05m
Southwest
Wed 7/157:55 am
MYR
- MDW
Nonstop2h 05m
Southwest
Deal found 6/3![Southwest logo]()
$276
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:59 pm
CVG
- SAV
1 stop4h 00m
Delta
Wed 10/145:30 am
SAV
- CVG
1 stop3h 24m
Delta
Deal found 6/5![Delta logo]()
$284
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:47 pm
ORD
- CHS
1 stop4h 01m
American Airlines
Sat 8/17:30 pm
CHS
- ORD
1 stop5h 00m
American Airlines
Deal found 6/7![American Airlines logo]()
$341
This JetBlue deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/249:42 am
ORD
- CHS
1 stop9h 10m
JetBlue
Mon 7/2710:58 am
CHS
- ORD
1 stop6h 18m
JetBlue
Deal found 6/7![JetBlue logo]()
$393
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:25 am
ORD
- HHH
Nonstop2h 38m
United Airlines
Tue 9/152:48 pm
HHH
- ORD
Nonstop3h 17m
United Airlines
Deal found 6/3![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:10 pm
CVG
- SAV
1 stop6h 35m
Southwest
Tue 9/151:10 pm
SAV
- CVG
1 stop7h 00m
Southwest
Deal found 6/7![Southwest logo]()
$278
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:40 am
ORD
- GSP
1 stop5h 01m
Delta
Sun 8/238:49 am
GSP
- ORD
1 stop4h 51m
Delta
Deal found 6/4![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:15 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
Sat 7/46:00 am
CLT
- ORD
1 stop4h 36m
United Airlines
Deal found 6/6![United Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:30 am
ORD
- GSP
1 stop4h 28m
Delta
Sun 10/187:15 am
GSP
- ORD
1 stop6h 22m
Delta
Deal found 6/3![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:00 am
CVG
- SAV
1 stop4h 45m
Southwest
Tue 8/111:10 pm
SAV
- CVG
1 stop7h 00m
Southwest
Deal found 6/5![Southwest logo]()
$302
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/11:55 pm
ORD
- GSP
Nonstop2h 05m
United Airlines
Thu 8/67:40 pm
GSP
- ORD
1 stop4h 51m
United Airlines
Deal found 6/6![United Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:40 pm
ORD
- GSP
1 stop7h 08m
Delta
Thu 7/97:10 am
GSP
- ORD
1 stop4h 27m
Delta
Deal found 6/6![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am
CVG
- SAV
2 stops10h 40m
Southwest
Sun 9/137:15 am
SAV
- CVG
1 stop5h 25m
Southwest
Deal found 6/7![Southwest logo]()
$306
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:30 am
ORD
- CLT
Nonstop2h 14m
United Airlines
Tue 7/218:05 am
CLT
- ORD
Nonstop2h 17m
United Airlines
Deal found 6/7![United Airlines logo]()
$297
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:02 am
ORD
- GSP
1 stop4h 53m
Delta
Sun 8/95:46 am
GSP
- ORD
1 stop3h 58m
Delta
Deal found 6/5![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:35 am
CVG
- SAV
2 stops7h 05m
Southwest
Sun 7/127:35 pm
SAV
- CVG
1 stop4h 55m
Southwest
Deal found 6/3![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:05 am
ORD
- GSP
1 stop4h 50m
Delta
Sun 8/97:15 am
GSP
- ORD
1 stop4h 27m
Delta
Deal found 6/7![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:05 am
ORD
- CHS
Nonstop2h 31m
United Airlines
Sat 8/226:30 am
CHS
- ORD
Nonstop2h 30m
United Airlines
Deal found 6/3![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:45 am
CVG
- MYR
2 stops10h 00m
Southwest
Sat 7/117:05 pm
MYR
- CVG
1 stop4h 45m
Southwest
Deal found 6/6![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am
CVG
- SAV
2 stops7h 50m
United Airlines
Sun 11/2210:00 am
SAV
- CVG
1 stop5h 01m
United Airlines
Deal found 6/3![United Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:40 am
ORD
- CLT
1 stop5h 46m
Delta
Tue 8/255:30 pm
CLT
- ORD
1 stop7h 32m
Delta
Deal found 6/4![Delta logo]()
$308
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/512:45 pm
CVG
- SAV
2 stops7h 50m
Southwest
Wed 7/81:25 pm
SAV
- CVG
2 stops7h 05m
Southwest
Deal found 6/4![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:25 pm
ORD
- CHS
Nonstop2h 26m
United Airlines
Sat 6/276:00 am
CHS
- ORD
Nonstop2h 33m
United Airlines
Deal found 6/3![United Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:35 am
ORD
- CLT
1 stop6h 00m
Delta
Sun 7/56:00 am
CLT
- ORD
1 stop5h 50m
Delta
Deal found 6/4![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:00 am
CVG
- SAV
2 stops12h 20m
Southwest
Wed 7/151:25 pm
SAV
- CVG
2 stops8h 30m
Southwest
Deal found 6/3![Southwest logo]()
$328
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:10 pm
ORD
- GSP
Nonstop2h 07m
United Airlines
Sun 6/286:10 am
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 6/3![United Airlines logo]()
$308
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:23 am
ORD
- SAV
1 stop4h 19m
Delta
Mon 8/3112:47 pm
SAV
- ORD
1 stop5h 04m
Delta
Deal found 6/4![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:10 am
CVG
- MYR
2 stops11h 30m
Southwest
Tue 9/88:15 am
MYR
- CVG
2 stops6h 40m
Southwest
Deal found 6/5![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:10 pm
ORD
- GSP
Nonstop2h 07m
United Airlines
Sun 6/216:10 am
GSP
- ORD
Nonstop2h 19m
United Airlines
Deal found 6/5![United Airlines logo]()
$309
Last-minute flights from Indiana to South CarolinaDiscover last-minute flight deals from Indiana to South Carolina. Data last updated June 8, 2026 and is based on user searches.
Discover last-minute flight deals from Indiana to South Carolina. Data last updated June 8, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:10 pm
CVG
- MYR
Nonstop1h 30m
Allegiant Air
Mon 6/159:47 pm
MYR
- CVG
Nonstop1h 37m
Allegiant Air
Deal found 6/3![Allegiant Air logo]()
$110
This Cheapflightsfares deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:37 pm
CVG
- MYR
Nonstop1h 32m
Allegiant Air
Mon 6/159:47 pm
MYR
- CVG
Nonstop1h 37m
Allegiant Air
Deal found 6/5![Allegiant Air logo]()
$109
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:46 am
CVG
- SAV
Nonstop1h 35m
Allegiant Air
Mon 6/296:00 am
SAV
- CVG
Nonstop1h 41m
Allegiant Air
Deal found 6/3![Allegiant Air logo]()
$101
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/262:05 pm
CVG
- MYR
Nonstop1h 30m
Allegiant Air
Sat 7/49:53 pm
MYR
- CVG
Nonstop1h 37m
Allegiant Air
Deal found 6/3![Allegiant Air logo]()
$106
This CheapOair deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:42 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Mon 7/136:00 am
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 6/5![Allegiant Air logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:43 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Fri 7/176:00 am
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:42 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Fri 7/176:00 am
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:42 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Thu 7/166:12 pm
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$105
This Cheapflightsfares deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:30 am
CVG
- MYR
Nonstop1h 32m
Allegiant Air
Sat 7/189:58 pm
MYR
- CVG
Nonstop1h 37m
Allegiant Air
Deal found 6/4![Allegiant Air logo]()
$111
This Cheapflightsfares deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/171:40 pm
CVG
- MYR
Nonstop1h 32m
Allegiant Air
Mon 7/209:30 pm
MYR
- CVG
Nonstop1h 37m
Allegiant Air
Deal found 6/3![Allegiant Air logo]()
$105
This CheapOair deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:43 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Sat 7/259:09 pm
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$103
This Cheapflightsfares deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:36 pm
CVG
- MYR
Nonstop1h 32m
Allegiant Air
Sat 8/19:58 pm
MYR
- CVG
Nonstop1h 37m
Allegiant Air
Deal found 6/5![Allegiant Air logo]()
$108
One-way flights from Indiana to South CarolinaSearch for one-way flight options from Indiana to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
Search for one-way flight options from Indiana to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
This CheapOair deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:30 am
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$45
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:37 pm
CVG
- MYR
Nonstop1h 32m
Allegiant Air
Deal found 6/6![Allegiant Air logo]()
$49
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/171:40 pm
CVG
- MYR
Nonstop1h 32m
Allegiant Air
Deal found 6/3![Allegiant Air logo]()
$53
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:43 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Deal found 6/6![Allegiant Air logo]()
$56
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:37 pm
CVG
- MYR
Nonstop1h 32m
Allegiant Air
Deal found 6/6![Allegiant Air logo]()
$57
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/101:40 pm
CVG
- MYR
Nonstop1h 32m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$61
This CheapOair deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:42 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Deal found 6/4![Allegiant Air logo]()
$63
This Super.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/292:05 pm
CVG
- MYR
Nonstop1h 30m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$67
This Super.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:33 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
Deal found 6/4![Allegiant Air logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/218:30 am
CVG
- MYR
Nonstop1h 32m
Allegiant Air
Deal found 6/7![Allegiant Air logo]()
$71
This Super.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:46 am
CVG
- SAV
Nonstop1h 35m
Allegiant Air
Deal found 6/3![Allegiant Air logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:55 am
ORD
- SAV
1 stop9h 00m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$81
Find flight deals from Indiana to South Carolina
Keep the following information in mind while searching for Indiana to South Carolina flight deals. Data was last updated June 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $100 (Cheapflightsfares) |
One-way from | $45 (CheapOair) |
Popular in | March |
Cheapest in | August |
Average price | $317 |
Good round-trip deal | $90 or less |
Good one-way deal | $49 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Indiana to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
Use the filters below to find and compare flights from Indiana to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Sat 7/11
6:29 am-9:43 am
Nonstop2h 14m
Charlotte Douglas
Wed 7/15
8:05 am-9:22 am
Nonstop2h 17m
$259
ChicagoHilton Head Island
ORD - HHH
ORDHHH
Chicago O'Hare Intl
Fri 9/11
10:25 am-2:03 pm
Nonstop2h 38m
Hilton Head Island
Tue 9/15
2:48 pm-5:05 pm
Nonstop3h 17m
$269
Quickest round-trip
ChicagoMyrtle Beach
MDW - MYR
MDWMYR
Chicago Midway
Sat 7/11
6:05 pm-9:10 pm
Nonstop2h 05m
Myrtle Beach Intl
Wed 7/15
7:55 am-9:00 am
Nonstop2h 05m
$276
CincinnatiSavannah
CVG - SAV
CVGSAV
Cincinnati Cinci./N. Kentucky
Fri 9/11
2:10 pm-8:45 pm
1 stop6h 35m
Savannah/Hilton Head
Tue 9/15
1:10 pm-8:10 pm
1 stop7h 00m
$278
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Sat 6/20
6:15 pm-9:29 pm
Nonstop2h 14m
Charlotte Douglas
Sat 7/4
6:00 am-9:36 am
1 stop4h 36m
$280
CincinnatiSavannah
CVG - SAV
CVGSAV
Cincinnati Cinci./N. Kentucky
Mon 10/12
7:59 pm-11:59 pm
1 stop4h 00m
Savannah/Hilton Head
Wed 10/14
5:30 am-8:54 am
1 stop3h 24m
$284
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Sat 8/1
1:55 pm-5:00 pm
Nonstop2h 05m
Greenville
Thu 8/6
7:40 pm-11:31 pm
1 stop4h 51m
$287
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 8/21
6:40 am-12:41 pm
1 stop5h 01m
Greenville
Sun 8/23
8:49 am-12:40 pm
1 stop4h 51m
$289
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Thu 10/15
5:30 am-10:58 am
1 stop4h 28m
Greenville
Sun 10/18
7:15 am-12:37 pm
1 stop6h 22m
$289
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 7/3
1:40 pm-9:48 pm
1 stop7h 08m
Greenville
Thu 7/9
7:10 am-10:37 am
1 stop4h 27m
$297
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Indiana to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Indiana with our price prediction graph.
CVG-SAV
ORD-MYR
MDW-MYR
ORD-SAV
CVG-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indiana to South Carolina
USIN-USSC
CVG-SAV
ORD-MYR
MDW-MYR
ORD-SAV
What is the cheapest month to book a flight from Indiana to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Indiana to South Carolina (average of $41). Flying from Indiana to South Carolina in April is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IN to SC?
Find hourly flight availability from Indiana to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 8, 2026.
One of the essential ways to save on airfare from Indiana to South Carolina is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 65% on airfare.
How much does it cost to fly round-trip from Indiana to South Carolina?
How far ahead should I book a flight from Indiana to South Carolina?
The best time to book flights from Indiana to South Carolina is 88 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 8, 2026.
Read through reviews of airlines operating flights from Indiana to South Carolina, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Indiana to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Indiana to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Indiana to South Carolina by cabin class
Find flights from Indiana to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Indiana and South Carolina flights
Browse other Indiana and South Carolina flight options. Last updated on June 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Indiana after your stay in South Carolina
Indiana to South Carolina flights
Consider these flights traveling from Indiana to South Carolina.
Top 5 airlines flying from Indiana to South Carolina
Discover the top 5 airlines that operate flights from Indiana to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$50 | Average$136 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$151 | Average$350 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$166 | Average$413 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$198 | Average$346 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$253 | Average$408 | FlexibilityNo cancel fee | On-time63% |