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South America

$114+ Cheap flights from the United States to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — BOG
May 27 — Jun 31
Wed 5/27
Wed 6/3
1 adult, Economy
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Cheap flight deals from USA to South America

Cheapest flights from USA to South America
Explore the most affordable flight options available from USA to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:41 am
FLL
-
MDE
1 stop22h 49m
Multiple Airlines
Tue 5/126:52 pm
MDE
-
FLL
1 stop21h 38m
Multiple Airlines
Deal found 4/22$268
This oojo deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:00 pm
FLL
-
MDE
Nonstop3h 25m
Avianca
Mon 6/291:00 pm
MDE
-
FLL
Nonstop3h 35m
Avianca
Deal found 4/22$273
This oojo deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:50 pm
MIA
-
MDE
Nonstop3h 25m
Avianca
Mon 6/111:50 pm
MDE
-
MIA
Nonstop3h 30m
Avianca
Deal found 4/22$273
This eDestinos deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:09 pm
MIA
-
MDE
1 stop6h 31m
Arajet
Tue 5/1910:05 am
MDE
-
MIA
1 stop6h 50m
Arajet
Deal found 4/23$274
This eDestinos deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:09 pm
MIA
-
MDE
1 stop6h 31m
Arajet
Thu 6/1110:05 am
MDE
-
MIA
1 stop8h 17m
Arajet
Deal found 4/24$275
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:35 am
FLL
-
MDE
1 stop14h 00m
Multiple Airlines
Wed 6/37:40 pm
MDE
-
FLL
1 stop20h 30m
Multiple Airlines
Deal found 4/23$278
This oojo deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:25 am
MIA
-
MDE
1 stop6h 45m
Avianca
Thu 8/611:50 pm
MDE
-
MIA
Nonstop3h 30m
Avianca
Deal found 4/22$279
This oojo deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:00 am
MIA
-
MDE
1 stop14h 30m
Avianca
Sun 5/3111:50 pm
MDE
-
MIA
Nonstop3h 30m
Avianca
Deal found 4/22$282
This oojo deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:00 pm
FLL
-
MDE
Nonstop3h 25m
Avianca
Wed 5/276:20 am
MDE
-
FLL
1 stop6h 35m
Avianca
Deal found 4/22$283
This oojo deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:50 pm
MIA
-
MDE
Nonstop3h 25m
Avianca
Mon 5/2510:45 pm
MDE
-
MIA
1 stop12h 40m
Avianca
Deal found 4/22$283
This oojo deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/223:20 pm
FLL
-
MDE
1 stop8h 05m
Avianca
Sat 5/301:00 pm
MDE
-
FLL
Nonstop3h 35m
Avianca
Deal found 4/22$284
This oojo deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:45 am
MIA
-
MDE
1 stop16h 25m
Avianca
Sun 5/3111:50 pm
MDE
-
MIA
Nonstop3h 30m
Avianca
Deal found 4/22$284

Find flight deals from USA to South America

Keep the following information in mind while searching for USA to South America flight deals. Data was last updated April 27, 2026.

Round-trip from

$268
(Kiwi.com)

One-way from

$114
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$524

Good round-trip deal

$207 or less

Good one-way deal

$96 or less
From USA to South America
Search Deals
One-way flight from USA to South America
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($62 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from USA to South America.
Search Deals
Price to beat on a one-way flight from USA to South America.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from USA to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
Use the filters below to find and compare flights from the United States to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OrlandoMedellín

MCO - MDE

MCOMDE

Orlando

Wed 6/3

1:41 pm-8:35 pm

1 stop7h 54m

Medellín Jose Maria Cordova Intl

Sun 6/7

5:00 am-2:13 pm

1 stop8h 13m

$297

OrlandoMedellín

MCO - MDE

MCOMDE

Orlando

Sat 5/9

5:00 pm-8:15 am

1 stop16h 15m

Medellín Jose Maria Cordova Intl

Tue 5/12

6:20 pm-12:02 pm

1 stop16h 42m

$297

OrlandoMedellín

MCO - MDE

MCOMDE

Orlando

Tue 6/2

5:00 pm-8:15 am

1 stop16h 15m

Medellín Jose Maria Cordova Intl

Tue 6/9

5:00 am-1:44 pm

1 stop7h 44m

$297

OrlandoMedellín

MCO - MDE

MCOMDE

Orlando

Fri 6/5

5:00 pm-8:15 am

1 stop16h 15m

Medellín Jose Maria Cordova Intl

Mon 6/8

9:15 am-10:25 pm

1 stop12h 10m

$297

OrlandoMedellín

MCO - MDE

MCOMDE

Orlando

Mon 6/1

5:00 pm-8:15 am

1 stop16h 15m

Medellín Jose Maria Cordova Intl

Sun 6/7

5:00 am-12:45 pm

1 stop6h 45m

$297

OrlandoMedellín

MCO - MDE

MCOMDE

Orlando

Wed 5/6

5:00 pm-8:15 am

1 stop16h 15m

Medellín Jose Maria Cordova Intl

Tue 5/19

9:15 am-10:29 pm

1 stop12h 14m

$297

OrlandoMedellín

MCO - MDE

MCOMDE

Orlando

Wed 6/10

2:42 pm-8:35 pm

1 stop6h 53m

Medellín Jose Maria Cordova Intl

Wed 8/12

12:40 pm-10:40 pm

1 stop9h 00m

$297

OrlandoMedellín

MCO - MDE

MCOMDE

Orlando

Wed 5/13

5:00 pm-8:15 am

1 stop16h 15m

Medellín Jose Maria Cordova Intl

Tue 5/19

9:15 am-10:40 pm

1 stop12h 25m

$297

OrlandoMedellín

MCO - MDE

MCOMDE

Orlando

Wed 5/20

5:59 pm-8:15 am

1 stop15h 16m

Medellín Jose Maria Cordova Intl

Mon 5/25

8:35 am-4:42 pm

1 stop7h 07m

$297

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Mon 5/18

6:14 pm-9:40 am

1 stop16h 26m

Medellín Jose Maria Cordova Intl

Mon 5/25

9:15 am-4:28 pm

1 stop6h 13m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
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6

Best time to book a flight from USA to South America

Have a flexible travel schedule? Discover the best time to fly to South America from USA with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the United States to South America

How far ahead should I book a flight from USA to South America?

The price you pay for your flight from USA to South America may vary depending on when you book. For the best chance of a lower fare, look to book 14 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from USA to South America?

Currently, September is the cheapest month in which you can book a flight from USA to South America (average of $537). Flying from USA to South America in December is currently the most expensive (average of $838). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from US to SA?

Find hourly flight availability from USA to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 27, 2026.

Unlike in the evening, when flights are generally more expensive, you can save up to 24% on flights from USA to South America by exploring options for tickets in the morning.

What is the cheapest day to fly from USA to South America?

Use this chart to determine the cheapest time to fly round-trip from USA to South America. Price data was last updated on April 25, 2026.

Travelers seeking maximum savings on their USA to South America flight should consider departing on Sunday mornings when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 27, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from the United States to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,462 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,462 reviews
Delta
7.9
Good
8,462 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.5
Good
1,580 reviews
Delta
7.9
Good
8,462 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.4
Good
1,912 reviews
Delta
7.9
Good
8,462 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,668 reviews
Delta
7.9
Good
8,462 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Avianca
6.5
Okay
2,513 reviews
Delta
7.9
Good
8,462 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from USA to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from USA to South America?

    Departing from USA to South America will take you 7h 54m. The distance between USA and South America is about 1585 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from USA to South America one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $46. However, be on the lookout for offers from JetBlue and Avianca, as they are both options that can get you from USA to South America for a low price.

  • Can I find deals for flights from USA to South America that include hotel bookings?

    Yes. In addition to deals on USA to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from USA to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from USA to South America.

  • Can I find deals for business class flights from USA to South America?

    Yes. Cheapflights offers flight deals from USA to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from USA to South America?

    Currently, September is the cheapest month in which you can book a flight from USA to South America (average of $537). Flying from USA to South America in December is currently the most expensive (average of $838). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for USA to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from USA to South America

Discover the top 10 airlines that operate flights from USA to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$54Average$175FlexibilityNo cancel feeOn-time62%
ArajetCheapest$106Average$442FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$108Average$408FlexibilityNo cancel feeOn-time65%
DeltaCheapest$118Average$782FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$126Average$591FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$128Average$747FlexibilityNo cancel feeOn-time69%
VolarisCheapest$132Average$274FlexibilityNo cancel feeOn-time79%
LATAM AirlinesCheapest$142Average$743FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$150Average$636FlexibilityNo cancel feeOn-time70%
JetBlueCheapest$168Average$522FlexibilityNo cancel feeOn-time62%

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