$158+ Cheap flights from the United States to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — BOG
Sep 10 — Sep 171
Round-trip
1 adult, Economy
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Find cheap flights from USA to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from USA to South America
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Cheapest flights from USA to South AmericaExplore the most affordable flight options available from USA to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2026.
Explore the most affordable flight options available from USA to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2026.
This CheapOair deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1912:59 am -
1 stop9h 21m
Thu 11/51:56 pm -
1 stop8h 34m
Deal found 8/7![Arajet logo]()
$337
This eDestinos deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1912:59 am -
1 stop9h 21m
Tue 10/272:23 pm -
1 stop8h 07m
Deal found 8/8![Arajet logo]()
$339
This CheapOair deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:59 am -
1 stop9h 21m
Mon 10/268:25 pm -
1 stop13h 05m
Deal found 8/8![Arajet logo]()
$341
This Expedia deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1912:00 pm -
1 stop8h 40m
Fri 10/238:25 pm -
1 stop13h 05m
Deal found 8/10![Arajet logo]()
$346
This Expedia deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:00 am -
1 stop8h 40m
Tue 11/172:05 pm -
1 stop8h 25m
Deal found 8/11![Arajet logo]()
$350
This Trip.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1312:59 am -
1 stop19h 41m
Fri 10/1610:05 am -
1 stop12h 25m
Deal found 8/8![Arajet logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:09 pm -
1 stop6h 31m
Tue 10/2010:05 am -
1 stop6h 50m
Deal found 8/9![Arajet logo]()
$352
This Expedia deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:09 pm -
1 stop6h 31m
Tue 9/1510:05 am -
1 stop6h 50m
Deal found 8/9![Arajet logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:09 pm -
1 stop6h 31m
Thu 9/2410:05 am -
1 stop8h 17m
Deal found 8/6![Arajet logo]()
$355
This FlightHub deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:25 pm -
1 stop6h 25m
Mon 11/97:55 am -
1 stop6h 50m
Deal found 8/10![LATAM Airlines logo]()
$356
This CheapOair deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:59 pm -
1 stop9h 33m
Wed 12/168:25 pm -
1 stop13h 05m
Deal found 8/10![Arajet logo]()
$357
This Justfly.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:30 pm -
1 stop7h 15m
Mon 11/25:30 am -
1 stop7h 00m
Deal found 8/8![LATAM Airlines logo]()
$357
Best flights from USA to South AmericaDiscover carefully curated flight deals from USA to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2026.
Discover carefully curated flight deals from USA to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:13 pm -
1 stop16h 27m
Thu 9/248:35 am -
1 stop6h 40m
Deal found 8/9![Copa Airlines logo]()
$365
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:30 am -
1 stop14h 45m
Fri 11/610:40 am -
1 stop10h 41m
Deal found 8/6![United Airlines logo]()
$389
This Avianca deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am -
Nonstop3h 20m
Sat 10/1011:50 pm -
Nonstop3h 30m
Deal found 8/10![Avianca logo]()
$414
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:30 pm -
1 stop27h 50m
Mon 9/2112:15 am -
Nonstop6h 05m
Deal found 8/10![Delta logo]()
$431
This Arajet deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/512:59 am -
1 stop9h 21m
Sun 10/117:00 pm -
1 stop14h 30m
Deal found 8/10![Arajet logo]()
$450
This JetBlue deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:15 pm -
Nonstop5h 52m
Wed 10/211:17 am -
Nonstop5h 43m
Deal found 8/10![JetBlue logo]()
$513
This Avianca deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:59 am -
2 stops16h 56m
Sun 10/44:05 am -
1 stop19h 40m
Deal found 8/10![Multiple Airlines logo]()
$537
This LATAM Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:59 pm -
Nonstop7h 56m
Wed 9/3012:30 pm -
1 stop10h 29m
Deal found 8/10![LATAM Airlines logo]()
$676
This Copa Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:13 pm -
1 stop16h 27m
Tue 9/296:20 pm -
1 stop20h 55m
Deal found 8/7![Copa Airlines logo]()
$365
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:20 am -
1 stop11h 55m
Wed 11/410:40 am -
1 stop12h 20m
Deal found 8/6![United Airlines logo]()
$389
This GOL deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/286:35 pm -
Nonstop9h 30m
Thu 2/1111:15 pm -
Nonstop9h 50m
Deal found 8/9![GOL logo]()
$825
This Copa Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:13 pm -
1 stop15h 02m
Tue 9/156:20 pm -
1 stop20h 55m
Deal found 8/8![Copa Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:00 am -
1 stop13h 10m
Mon 11/1610:40 am -
1 stop14h 05m
Deal found 8/6![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am -
2 stops15h 20m
Thu 9/2412:05 pm -
1 stop11h 50m
Deal found 8/10![Delta logo]()
$445
This Copa Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:13 pm -
1 stop21h 02m
Sun 9/136:20 pm -
1 stop20h 55m
Deal found 8/8![Copa Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:43 pm -
1 stop25h 27m
Wed 10/219:45 am -
1 stop14h 13m
Deal found 8/7![United Airlines logo]()
$398
This Copa Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:12 pm -
1 stop15h 03m
Mon 8/246:20 pm -
1 stop20h 55m
Deal found 8/10![Copa Airlines logo]()
$380
This JetBlue deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:15 pm -
Nonstop5h 52m
Thu 10/221:17 am -
Nonstop5h 43m
Deal found 8/6![JetBlue logo]()
$513
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:05 am -
2 stops18h 10m
Tue 10/68:55 am -
2 stops32h 50m
Deal found 8/10![Delta logo]()
$467
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:55 am -
2 stops12h 15m
Tue 9/1511:55 am -
1 stop10h 50m
Deal found 8/10![Avianca logo]()
$523
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:50 pm -
1 stop26h 20m
Sat 10/109:45 am -
1 stop11h 59m
Deal found 8/10![United Airlines logo]()
$398
This Arajet deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:59 am -
1 stop19h 41m
Sun 10/117:00 pm -
1 stop14h 30m
Deal found 8/6![Arajet logo]()
$534
This Copa Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:13 pm -
1 stop21h 02m
Sat 10/245:00 am -
1 stop10h 15m
Deal found 8/10![Copa Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:00 am -
2 stops16h 35m
Sun 10/115:50 am -
2 stops11h 55m
Deal found 8/6![Delta logo]()
$471
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:55 pm -
1 stop28h 15m
Wed 9/239:45 am -
1 stop10h 48m
Deal found 8/9![United Airlines logo]()
$398
This Avianca deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:05 pm -
1 stop9h 40m
Thu 8/2711:45 am -
1 stop10h 45m
Deal found 8/9![Avianca logo]()
$543
This Copa Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:11 pm -
1 stop17h 44m
Wed 11/185:00 am -
1 stop10h 13m
Deal found 8/10![Copa Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:05 am -
2 stops17h 40m
Tue 9/158:30 am -
2 stops13h 29m
Deal found 8/7![Delta logo]()
$471
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:43 pm -
1 stop25h 27m
Sun 10/259:45 am -
1 stop14h 00m
Deal found 8/7![United Airlines logo]()
$398
This Copa Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:13 pm -
1 stop21h 02m
Sun 10/256:20 pm -
1 stop20h 55m
Deal found 8/10![Copa Airlines logo]()
$385
Last-minute flights from USA to South AmericaDiscover last-minute flight deals from USA to South America. Data last updated August 11, 2026 and is based on user searches.
Discover last-minute flight deals from USA to South America. Data last updated August 11, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:30 pm -
1 stop7h 15m
Wed 9/238:30 am -
1 stop6h 25m
Deal found 8/10![LATAM Airlines logo]()
$367
This Expedia deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:09 pm -
1 stop6h 31m
Tue 9/1510:05 am -
1 stop6h 50m
Deal found 8/9![Arajet logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:09 pm -
1 stop6h 31m
Thu 10/1510:05 am -
1 stop8h 17m
Deal found 8/6![Arajet logo]()
$365
This Booking.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:13 pm -
1 stop16h 27m
Wed 9/166:20 pm -
1 stop20h 55m
Deal found 8/7![Copa Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:09 pm -
1 stop6h 31m
Thu 9/2410:05 am -
1 stop8h 17m
Deal found 8/6![Arajet logo]()
$355
This FlightHub deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:09 pm -
1 stop6h 31m
Tue 9/1510:05 am -
1 stop6h 50m
Deal found 8/6![Arajet logo]()
$357
This Booking.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:09 pm -
1 stop6h 31m
Sat 9/1210:05 am -
1 stop6h 50m
Deal found 8/9![Arajet logo]()
$358
This eDestinos deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:09 pm -
1 stop6h 31m
Tue 9/1510:05 am -
1 stop6h 50m
Deal found 8/9![Arajet logo]()
$361
This Trip.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1312:59 am -
1 stop19h 41m
Fri 10/1610:05 am -
1 stop12h 25m
Deal found 8/8![Arajet logo]()
$352
This Copa Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:13 pm -
1 stop21h 02m
Mon 9/289:15 am -
1 stop6h 00m
Deal found 8/7![Copa Airlines logo]()
$365
This CheapOair deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:12 pm -
1 stop12h 49m
Sat 9/262:34 am -
1 stop10h 58m
Deal found 8/10![Multiple Airlines logo]()
$370
This LATAM Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 pm -
1 stop7h 15m
Wed 10/218:30 am -
1 stop6h 25m
Deal found 8/9![LATAM Airlines logo]()
$366
One-way flights from USA to South AmericaSearch for one-way flight options from USA to South America. Find affordable one-way fares based on user searches. Data last updated August 11, 2026.
Search for one-way flight options from USA to South America. Find affordable one-way fares based on user searches. Data last updated August 11, 2026.
This Justfly.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:09 pm -
1 stop6h 31m
Deal found 8/10![Arajet logo]()
$158
This eDestinos deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2311:59 pm -
1 stop17h 29m
Deal found 8/6![Arajet logo]()
$159
This Booking.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:59 pm -
1 stop19h 41m
Deal found 8/9![Arajet logo]()
$160
This FlightHub deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:30 pm -
1 stop7h 15m
Deal found 8/10![LATAM Airlines logo]()
$160
This Trip.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/811:59 pm -
1 stop19h 41m
Deal found 8/8![Arajet logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:48 pm -
2 stops17h 57m
Deal found 8/9![Multiple Airlines logo]()
$161
This Super.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:09 pm -
1 stop6h 31m
Deal found 8/9![Arajet logo]()
$162
This Trip.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/179:33 pm -
2 stops45h 17m
Deal found 8/10![Multiple Airlines logo]()
$163
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am -
1 stop16h 15m
Deal found 8/7![United Airlines logo]()
$164
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:00 am -
1 stop13h 15m
Deal found 8/7![United Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:10 am -
1 stop11h 15m
Deal found 8/7![Multiple Airlines logo]()
$164
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:29 am -
1 stop14h 41m
Deal found 8/7![United Airlines logo]()
$165
Find flight deals from USA to South America
Keep the following information in mind while searching for USA to South America flight deals. Data was last updated August 11, 2026.
Round-trip from | $337 (CheapOair) |
|---|---|
One-way from | $158 (Justfly.com) |
Popular in | December |
Cheapest in | February |
Average price | $603 |
Good round-trip deal | $319 or less |
Good one-way deal | $136 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from USA to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from the United States to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Fort LauderdaleMedellín
FLL Fort Lauderdale - MDE Medellín Jose Maria Cordova Intl
FLLMDE
Fort Lauderdale
Fri 9/18
6:13 pm-9:40 am
1 stop16h 27m
Medellín Jose Maria Cordova Intl
Thu 9/24
8:35 am-4:15 pm
1 stop6h 40m
$365
Fort LauderdaleMedellín
FLL Fort Lauderdale - MDE Medellín Jose Maria Cordova Intl
FLLMDE
Fort Lauderdale
Fri 9/25
6:13 pm-9:40 am
1 stop16h 27m
Medellín Jose Maria Cordova Intl
Tue 9/29
6:20 pm-4:15 pm
1 stop20h 55m
$365
Fort LauderdaleMedellín
FLL Fort Lauderdale - MDE Medellín Jose Maria Cordova Intl
FLLMDE
Fort Lauderdale
Thu 9/10
6:13 pm-8:15 am
1 stop15h 02m
Medellín Jose Maria Cordova Intl
Tue 9/15
6:20 pm-4:15 pm
1 stop20h 55m
$375
Fort LauderdaleMedellín
FLL Fort Lauderdale - MDE Medellín Jose Maria Cordova Intl
FLLMDE
Fort Lauderdale
Fri 9/11
6:13 pm-2:15 pm
1 stop21h 02m
Medellín Jose Maria Cordova Intl
Sun 9/13
6:20 pm-4:15 pm
1 stop20h 55m
$375
Fort LauderdaleMedellín
FLL Fort Lauderdale - MDE Medellín Jose Maria Cordova Intl
FLLMDE
Fort Lauderdale
Fri 8/21
6:12 pm-8:15 am
1 stop15h 03m
Medellín Jose Maria Cordova Intl
Mon 8/24
6:20 pm-4:15 pm
1 stop20h 55m
$380
Fort LauderdaleMedellín
FLL Fort Lauderdale - MDE Medellín Jose Maria Cordova Intl
FLLMDE
Fort Lauderdale
Thu 10/15
6:13 pm-2:15 pm
1 stop21h 02m
Medellín Jose Maria Cordova Intl
Sat 10/24
5:00 am-4:15 pm
1 stop10h 15m
$385
Fort LauderdaleMedellín
FLL Fort Lauderdale - MDE Medellín Jose Maria Cordova Intl
FLLMDE
Fort Lauderdale
Wed 11/11
5:11 pm-10:55 am
1 stop17h 44m
Medellín Jose Maria Cordova Intl
Wed 11/18
5:00 am-3:13 pm
1 stop10h 13m
$385
Fort LauderdaleMedellín
FLL Fort Lauderdale - MDE Medellín Jose Maria Cordova Intl
FLLMDE
Fort Lauderdale
Sat 10/3
6:13 pm-2:15 pm
1 stop21h 02m
Medellín Jose Maria Cordova Intl
Sun 10/25
6:20 pm-4:15 pm
1 stop20h 55m
$385
NewarkMedellín
EWR Newark - MDE Medellín Jose Maria Cordova Intl
EWRMDE
Newark
Sat 10/31
7:30 am-9:15 pm
1 stop14h 45m
Medellín Jose Maria Cordova Intl
Fri 11/6
10:40 am-9:21 pm
1 stop10h 41m
$389
NewarkMedellín
EWR Newark - MDE Medellín Jose Maria Cordova Intl
EWRMDE
Newark
Wed 10/28
10:20 am-9:15 pm
1 stop11h 55m
Medellín Jose Maria Cordova Intl
Wed 11/4
10:40 am-11:00 pm
1 stop12h 20m
$389
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from USA to South America
Have a flexible travel schedule? Discover the best time to fly to South America from USA with our price prediction graph.
MIA-MDE
EWR-MDE
LGA-MDE
FLL-MDE
MIA-LIM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from the United States to South America
US0-0SA
MIA-MDE
EWR-MDE
LGA-MDE
FLL-MDE
What is the cheapest month to book a flight from USA to South America?
Currently, October is the cheapest month in which you can book a flight from USA to South America (average of $571). Flying from USA to South America in December is currently the most expensive (average of $864). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from US to SA?
Find hourly flight availability from USA to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 11, 2026.
Unlike in the evening, when flights are generally more expensive, you can save up to 16% on flights from USA to South America by exploring options for tickets in the morning.
How far ahead should I book a flight from USA to South America?
The price you pay for your flight from USA to South America may vary depending on when you book. For the best chance of a lower fare, look to book 15 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from USA to South America?
Use this chart to determine the cheapest time to fly round-trip from USA to South America. Price data was last updated on August 8, 2026.
Travelers seeking maximum savings on their USA to South America flight should consider departing on Sunday mornings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated August 11, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from the United States to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from USA to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for USA to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from USA to South America by cabin class
Find flights from USA to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
USA and South America flights
Browse other USA and South America flight options. Last updated on August 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South America
Find the right flight back to USA after your stay in South America
Fly to South America countries
Consider these flights traveling to countries located in South America.
USA to South America flights
Consider these flights traveling from USA to South America.
Top 10 airlines flying from USA to South America
Discover the top 10 airlines that operate flights from USA to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$54 | Average$110 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$126 | Average$612 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$133 | Average$469 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$148 | Average$743 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$149 | Average$339 | FlexibilityNo cancel fee | On-time79% | |
| Cheapest$162 | Average$543 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$162 | Average$850 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$162 | Average$794 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$192 | Average$659 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$234 | Average$921 | FlexibilityNo cancel fee | On-time67% |