$157+ Cheap flights from the United States to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — BOG
Oct 14 — Oct 211
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from USA to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from USA to South America
Cheapest
Best
Last-minute
One-way
Cheapest flights from USA to South AmericaExplore the most affordable flight options available from USA to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from USA to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:22 pm -
1 stop14h 53m
Sat 11/146:20 pm -
1 stop6h 17m
Deal found 9/12![Copa Airlines logo]()
$334
This Super.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:59 pm -
1 stop19h 41m
Thu 2/251:56 pm -
1 stop9h 34m
Deal found 9/14![Arajet logo]()
$372
This Trip.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:52 pm -
1 stop23h 48m
Tue 11/310:17 am -
1 stop6h 38m
Deal found 9/11![Arajet logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:59 pm -
1 stop8h 32m
Fri 11/201:00 am -
Nonstop6h 10m
Deal found 9/10![Multiple Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:09 pm -
1 stop11h 06m
Thu 11/262:30 am -
1 stop9h 09m
Deal found 9/10![Arajet logo]()
$378
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:52 pm -
2 stops25h 18m
Tue 11/1010:40 am -
2 stops24h 43m
Deal found 9/9![United Airlines logo]()
$378
This eDestinos deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2711:59 pm -
1 stop9h 21m
Wed 12/98:25 pm -
1 stop13h 05m
Deal found 9/13![Arajet logo]()
$378
This Orbitz deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/254:02 pm -
1 stop9h 08m
Sat 10/312:34 am -
1 stop10h 58m
Deal found 9/13![Arajet logo]()
$379
This Booking.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:45 pm -
1 stop10h 59m
Thu 11/122:30 am -
1 stop9h 09m
Deal found 9/11![Arajet logo]()
$380
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:59 pm -
1 stop8h 32m
Thu 11/123:00 am -
1 stop12h 08m
Deal found 9/10![Arajet logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:09 pm -
1 stop11h 06m
Thu 12/31:00 am -
Nonstop6h 10m
Deal found 9/12![Multiple Airlines logo]()
$382
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/295:30 am -
1 stop11h 58m
Wed 12/98:25 pm -
1 stop13h 05m
Deal found 9/11![Arajet logo]()
$382
Best flights from USA to South AmericaDiscover carefully curated flight deals from USA to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from USA to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:21 am -
1 stop9h 24m
Mon 10/2612:40 pm -
1 stop9h 04m
Deal found 9/14![Copa Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:28 pm -
3 stops28h 42m
Thu 11/1210:40 am -
1 stop11h 19m
Deal found 9/12![United Airlines logo]()
$398
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:40 am -
1 stop6h 40m
Thu 10/221:30 pm -
1 stop7h 44m
Deal found 9/10![JetBlue logo]()
$434
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:25 pm -
1 stop6h 25m
Fri 11/137:55 am -
1 stop6h 50m
Deal found 9/13![Delta logo]()
$434
This Arajet deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:09 pm -
1 stop6h 31m
Wed 10/288:25 pm -
1 stop21h 57m
Deal found 9/11![Arajet logo]()
$457
This Avianca deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:15 pm -
Nonstop3h 45m
Fri 9/2512:35 pm -
Nonstop3h 50m
Deal found 9/11![Avianca logo]()
$470
This oojo deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:50 am -
Nonstop5h 50m
Sat 11/71:00 am -
Nonstop6h 10m
Deal found 9/14![Sky Airline logo]()
$471
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:59 am -
1 stop19h 41m
Wed 11/49:07 am -
2 stops24h 23m
Deal found 9/14![Multiple Airlines logo]()
$553
This GOL deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:40 pm -
Nonstop9h 35m
Thu 11/53:25 pm -
1 stop17h 35m
Deal found 9/9![GOL logo]()
$699
This Copa Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:57 am -
1 stop9h 18m
Sun 10/259:15 am -
1 stop15h 30m
Deal found 9/12![Copa Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:58 pm -
1 stop29h 12m
Wed 11/1810:40 am -
2 stops24h 31m
Deal found 9/14![United Airlines logo]()
$406
This JetBlue deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:00 pm -
Nonstop3h 33m
Sun 11/152:30 pm -
Nonstop3h 35m
Deal found 9/9![JetBlue logo]()
$453
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:20 pm -
1 stop27h 50m
Mon 11/910:40 am -
1 stop12h 20m
Deal found 9/10![United Airlines logo]()
$418
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:20 am -
2 stops11h 30m
Mon 11/167:55 am -
2 stops15h 08m
Deal found 9/14![Delta logo]()
$471
This Copa Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:11 pm -
1 stop21h 04m
Tue 11/109:15 am -
1 stop5h 58m
Deal found 9/13![Copa Airlines logo]()
$431
This Arajet deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:59 pm -
1 stop17h 29m
Fri 11/2010:00 am -
1 stop12h 30m
Deal found 9/10![Arajet logo]()
$479
This JetBlue deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1412:00 pm -
Nonstop3h 33m
Fri 11/202:25 pm -
Nonstop3h 34m
Deal found 9/9![JetBlue logo]()
$453
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:24 pm -
2 stops25h 46m
Fri 11/1310:40 am -
3 stops28h 03m
Deal found 9/9![United Airlines logo]()
$420
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:13 pm -
1 stop21h 02m
Sun 10/253:15 pm -
1 stop24h 00m
Deal found 9/11![Copa Airlines logo]()
$432
This Arajet deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2812:45 pm -
1 stop10h 59m
Wed 12/21:00 am -
1 stop17h 22m
Deal found 9/12![Arajet logo]()
$482
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:19 am -
1 stop16h 51m
Wed 11/1110:40 am -
1 stop14h 05m
Deal found 9/13![United Airlines logo]()
$429
This Avianca deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:35 pm -
1 stop8h 55m
Wed 10/213:30 am -
1 stop9h 25m
Deal found 9/12![Avianca logo]()
$571
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:38 pm -
1 stop18h 37m
Tue 9/226:20 pm -
1 stop17h 25m
Deal found 9/11![Copa Airlines logo]()
$433
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:30 pm -
1 stop15h 35m
Wed 10/2812:10 pm -
1 stop11h 43m
Deal found 9/10![Delta logo]()
$539
This JetBlue deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:20 am -
1 stop7h 01m
Sun 11/222:25 pm -
1 stop7h 54m
Deal found 9/13![JetBlue logo]()
$491
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:50 am -
Nonstop5h 50m
Sat 10/312:55 am -
3 stops44h 00m
Deal found 9/14![Multiple Airlines logo]()
$624
This Arajet deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:59 pm -
1 stop9h 21m
Tue 11/172:05 pm -
1 stop8h 25m
Deal found 9/10![Arajet logo]()
$522
This Copa Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:31 pm -
1 stop14h 44m
Tue 10/2712:40 pm -
1 stop9h 04m
Deal found 9/14![Copa Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:27 pm -
1 stop8h 43m
Tue 11/1010:40 am -
2 stops26h 38m
Deal found 9/13![United Airlines logo]()
$450
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:18 am -
1 stop22h 42m
Fri 10/238:55 am -
2 stops14h 58m
Deal found 9/10![Delta logo]()
$551
Last-minute flights from USA to South AmericaDiscover last-minute flight deals from USA to South America. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from USA to South America. Data last updated September 14, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/274:02 pm -
1 stop9h 08m
Tue 9/292:30 am -
1 stop9h 09m
Deal found 9/13![Arajet logo]()
$388
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:02 pm -
1 stop9h 08m
Mon 10/191:55 am -
1 stop9h 30m
Deal found 9/10![Arajet logo]()
$383
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:25 am -
1 stop7h 20m
Fri 10/239:15 am -
1 stop6h 22m
Deal found 9/11![Copa Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:30 pm -
1 stop24h 10m
Sun 11/112:40 pm -
1 stop23h 50m
Deal found 9/10![Delta logo]()
$388
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:55 pm -
1 stop10h 49m
Thu 11/122:30 am -
1 stop9h 09m
Deal found 9/14![Arajet logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:21 am -
1 stop5h 34m
Sun 10/259:15 am -
1 stop12h 29m
Deal found 9/10![Copa Airlines logo]()
$390
This Orbitz deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/254:02 pm -
1 stop9h 08m
Sat 10/312:34 am -
1 stop10h 58m
Deal found 9/13![Arajet logo]()
$379
This eDestinos deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:50 am -
Nonstop5h 50m
Sat 11/71:00 am -
Nonstop6h 10m
Deal found 9/10![Sky Airline logo]()
$391
This oojo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:50 am -
Nonstop5h 50m
Tue 11/31:00 am -
Nonstop6h 10m
Deal found 9/11![Sky Airline logo]()
$389
This Trip.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:52 pm -
1 stop23h 48m
Tue 11/310:17 am -
1 stop6h 38m
Deal found 9/11![Arajet logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:55 pm -
1 stop11h 06m
Thu 11/122:30 am -
1 stop9h 09m
Deal found 9/14![Arajet logo]()
$384
This Booking.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:45 pm -
1 stop10h 59m
Thu 11/122:30 am -
1 stop9h 09m
Deal found 9/11![Arajet logo]()
$380
One-way flights from USA to South AmericaSearch for one-way flight options from USA to South America. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
Search for one-way flight options from USA to South America. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
This JetBlue deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:25 am -
1 stop6h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![JetBlue logo]()
$157
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:59 pm -
1 stop19h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Arajet logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:09 pm -
1 stop6h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Arajet logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:21 am -
2 stops17h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:09 pm -
1 stop6h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Arajet logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:30 pm -
2 stops21h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:22 pm -
1 stop20h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Copa Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/123:31 pm -
1 stop13h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Volaris logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:41 am -
1 stop10h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Copa Airlines logo]()
$169
This Mytrip deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:09 pm -
2 stops19h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$170
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:55 pm -
1 stop11h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Arajet logo]()
$171
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am -
2 stops15h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![United Airlines logo]()
$171
Find flight deals from USA to South America
Keep the following information in mind while searching for USA to South America flight deals. Data was last updated September 14, 2026.
Round-trip from | $334 (Kiwi.com) |
|---|---|
One-way from | $157 (JetBlue) |
Popular in | December |
Cheapest in | February |
Average price | $545 |
Good round-trip deal | $323 or less |
Good one-way deal | $144 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from USA to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from the United States to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MiamiMedellín
MIA Miami - MDE Medellín Jose Maria Cordova Intl
MIAMDE
Miami
Tue 11/10
4:25 pm-6:05 pm
1 stop25h 40m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Fort LauderdaleMedellín
FLL Fort Lauderdale - MDE Medellín Jose Maria Cordova Intl
FLLMDE
Fort Lauderdale
Tue 11/10
7:00 am-10:10 pm
2 stops15h 10m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$171
MiamiMedellín
MIA Miami - MDE Medellín Jose Maria Cordova Intl
MIAMDE
Miami
Tue 11/10
8:45 am-10:10 pm
1 stop13h 25m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$171
Quickest round-trip
OrlandoMedellín
MCO Orlando - MDE Medellín Jose Maria Cordova Intl
MCOMDE
Orlando
Fri 10/9
10:05 am-2:34 pm
1 stop5h 29m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$172
MiamiLima
MIA Miami - LIM Lima J Chavez Intl
MIALIM
Miami
Fri 12/4
3:31 pm-4:55 am
1 stop13h 24m
Lima J Chavez Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$174
MiamiMedellín
MIA Miami - MDE Medellín Jose Maria Cordova Intl
MIAMDE
Miami
Tue 10/27
6:35 am-2:15 pm
1 stop8h 40m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$174
MiamiMedellín
MIA Miami - MDE Medellín Jose Maria Cordova Intl
MIAMDE
Miami
Fri 10/23
5:57 am-2:15 pm
1 stop9h 18m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$174
Fort LauderdaleMedellín
FLL Fort Lauderdale - MDE Medellín Jose Maria Cordova Intl
FLLMDE
Fort Lauderdale
Mon 11/9
8:52 pm-10:10 pm
2 stops25h 18m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$177
MiamiMedellín
MIA Miami - MDE Medellín Jose Maria Cordova Intl
MIAMDE
Miami
Wed 11/4
5:28 pm-10:10 pm
3 stops28h 42m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$177
NewarkMedellín
EWR Newark - MDE Medellín Jose Maria Cordova Intl
EWRMDE
Newark
Fri 9/18
12:00 pm-9:10 pm
1 stop10h 10m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$179
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from USA to South America
Have a flexible travel schedule? Discover the best time to fly to South America from USA with our price prediction graph.
FLL-MDE
EWR-MDE
MIA-MDE
MIA-LIM
MCO-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from the United States to South America
US0-0SA
FLL-MDE
EWR-MDE
MIA-MDE
MIA-LIM
What is the cheapest month to book a flight from USA to South America?
Currently, April is the cheapest month in which you can book a flight from USA to South America (average of $591). Flying from USA to South America in December is currently the most expensive (average of $879). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from US to SA?
Find hourly flight availability from USA to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 14, 2026.
Unlike in the evening, when flights are generally more expensive, you can save up to 21% on flights from USA to South America by exploring options for tickets in the morning.
How far ahead should I book a flight from USA to South America?
The price you pay for your flight from USA to South America may vary depending on when you book. For the best chance of a lower fare, look to book 6 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from USA to South America?
Use this chart to determine the cheapest time to fly round-trip from USA to South America. Price data was last updated on September 12, 2026.
Travelers seeking maximum savings on their USA to South America flight should consider departing on Sunday mornings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 14, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from the United States to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.8
Entertainment
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Entertainment
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Entertainment
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Entertainment
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Entertainment
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Entertainment
7.8
Crew
8.5
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from USA to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top countries
Top destinations
Alternative routes for USA to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from USA to South America by cabin class
Find flights from USA to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
USA and South America flights
Browse other USA and South America flight options. Last updated on September 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South America
Find the right flight back to USA after your stay in South America
Fly to South America countries
Consider these flights traveling to countries located in South America.
USA to South America flights
Consider these flights traveling from USA to South America.
Top 10 airlines flying from USA to South America
Discover the top 10 airlines that operate flights from USA to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$54 | Average$122 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$124 | Average$537 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$126 | Average$641 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$129 | Average$475 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$133 | Average$822 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$148 | Average$782 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$149 | Average$326 | FlexibilityNo cancel fee | On-time79% | |
| Cheapest$162 | Average$856 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$184 | Average$688 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$234 | Average$963 | FlexibilityNo cancel fee | On-time67% |