Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to South America as you normally would.
Due to multiple factors, expect to potentially pay more when booking in April. For low rates, August can be a great choice for travel to South America. Flights to South America from Des Moines in August are about $857 on average during August, but can be found for as low as $576.
||$771||$1,059||No cancel fee||71%|
||$814||$914||No cancel fee||N/A|
||$833||$1,002||No cancel fee||67%|
||$857||$1,211||No cancel fee||69%|