$309+ Cheap flights from Des Moines (DSM) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
DSM — BOG
Jul 16 — Jul 231

What is the cheapest time of day to fly from DSM to SA?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to South America as you normally would.

Cheap Des Moines to South America flights in July & August 2024

Find cheap flight options from Des Moines to South America specifically for the months of July and August 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,800,118 searches. Prices were last updated on July 11, 2024.
This United deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/246:00 amDSM - GYE
2 stops27h 10mMultiple Airlines
Wed 9/48:30 amGYE - DSM
2 stops29h 49mMultiple Airlines
Deal found 7/9$516
This United deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/223:00 pmDSM - GYE
2 stops18h 10mMultiple Airlines
Sat 8/318:30 amGYE - DSM
2 stops29h 49mMultiple Airlines
Deal found 7/9$536
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/246:55 amDSM - GYE
1 stop15h 09mAmerican Airlines
Wed 9/46:00 amGYE - DSM
2 stops14h 27mAmerican Airlines
Deal found 7/9$566
This United deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/62:59 pmDSM - GYE
2 stops26h 11mMultiple Airlines
Tue 8/138:30 amGYE - DSM
2 stops29h 44mMultiple Airlines
Deal found 7/9$643
This mytrip.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/229:00 amDSM - GYE
3 stops37h 59mMultiple Airlines
Sat 8/314:20 amGYE - DSM
3 stops32h 24mMultiple Airlines
Deal found 7/9$663
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/226:00 amDSM - GYE
2 stops16h 04mAmerican Airlines
Sat 8/316:05 amGYE - DSM
1 stop15h 51mAmerican Airlines
Deal found 7/9$683
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/76:33 pmDSM - LIM
1 stop11h 07mDelta
Wed 8/1411:20 pmLIM - DSM
1 stop18h 23mDelta
Deal found 7/10$868
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/711:52 amDSM - LIM
2 stops17h 48mDelta
Wed 8/141:30 pmLIM - DSM
2 stops20h 52mDelta
Deal found 7/10$873
This United deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/243:00 pmDSM - GYE
2 stops11h 40mMultiple Airlines
Tue 9/33:40 amGYE - DSM
2 stops18h 47mMultiple Airlines
Deal found 7/9$877

Des Moines to South America 2024 flight deals

Discover exclusive flight deals for travel between Des Moines and South America in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,800,118 searches. Data last updated July 11, 2024.
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/412:39 pmDSM - UIO
2 stops24h 37mAmerican Airlines
Fri 11/153:05 pmUIO - DSM
2 stops21h 14mAmerican Airlines
Deal found 7/10$471
This United deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/56:54 pmDSM - UIO
2 stops52h 36mUnited Airlines
Fri 11/151:35 amUIO - DSM
2 stops13h 48mUnited Airlines
Deal found 7/10$489
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/23:20 pmDSM - UIO
2 stops33h 10mUnited Airlines
Fri 11/151:35 amUIO - DSM
2 stops21h 11mUnited Airlines
Deal found 7/10$500
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/53:30 pmDSM - UIO
2 stops21h 46mAmerican Airlines
Sat 11/163:05 pmUIO - DSM
2 stops20h 30mAmerican Airlines
Deal found 7/10$501
This United deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/246:00 amDSM - GYE
2 stops27h 10mMultiple Airlines
Wed 9/48:30 amGYE - DSM
2 stops29h 49mMultiple Airlines
Deal found 7/9$516
This United deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/36:54 pmDSM - UIO
2 stops28h 36mUnited Airlines
Fri 11/151:35 amUIO - DSM
2 stops13h 48mUnited Airlines
Deal found 7/10$521
This United deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/223:00 pmDSM - GYE
2 stops18h 10mMultiple Airlines
Sat 8/318:30 amGYE - DSM
2 stops29h 49mMultiple Airlines
Deal found 7/9$536
This United deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/43:20 pmDSM - UIO
2 stops32h 10mUnited Airlines
Thu 11/141:35 amUIO - DSM
2 stops21h 11mUnited Airlines
Deal found 7/10$536
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/35:49 pmDSM - UIO
2 stops21h 38mAmerican Airlines
Sun 11/173:05 pmUIO - DSM
2 stops22h 43mAmerican Airlines
Deal found 7/10$541

Des Moines to South America flights leaving soon

Find last-minute flight options from Des Moines to South America for spontaneous travel. Discover available flights and compare prices based on user searches. Secure great deals and offers for spontaneous trips with quick booking options. Over the last 7 days, Cheapflights users made 2,800,118 searches. Data last updated July 11, 2024.
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/142:05 pmDSM - SCL
1 stop15h 55mDelta
Wed 7/2412:25 amSCL - DSM
2 stops22h 54mDelta
Deal found 7/10$1,432

One-way flights to South America from Des Moines

Search for one-way flight options from Des Moines to South America. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 2,800,118 searches. Data last updated July 11, 2024.
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/910:58 amDSM - LIM
2 stops32h 07mMultiple Airlines
Deal found 7/10$309
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/910:58 amDSM - LIM
3 stops42h 02mMultiple Airlines
Deal found 7/10$336
This FlightHub deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/58:00 amDSM - SCL
2 stops18h 10mAvianca
Deal found 7/10$509
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/26:00 amDSM - SCL
1 stop22h 20mDelta
Deal found 7/10$532
This United deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/56:40 pmDSM - SCL
2 stops35h 10mUnited Airlines
Deal found 7/11$548
This United deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/46:40 pmDSM - SCL
2 stops59h 10mUnited Airlines
Deal found 7/10$572
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/95:57 amDSM - LIM
1 stop15h 08mDelta
Deal found 7/10$573
This United deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/36:40 pmDSM - SCL
2 stops59h 10mUnited Airlines
Deal found 7/10$612
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/312:41 pmDSM - SCL
2 stops17h 14mAmerican Airlines
Deal found 7/11$622

Find flights from Des Moines to South America within your budget

Customize your flight search to find flights from Des Moines to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,800,118 searches. Data last updated July 11, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$471 - $662

Route

Depart

Return

Price

Des MoinesQuito Mariscal Sucr

DSM - UIO

DSMUIO

Des Moines

Mon 11/4

2 stops24h 37m

Quito Mariscal Sucr

Fri 11/15

2 stops21h 14m

$471

Des MoinesQuito Mariscal Sucr

DSM - UIO

DSMUIO

Des Moines

Tue 11/5

2 stops52h 36m

Quito Mariscal Sucr

Fri 11/15

2 stops13h 48m

$489

Des MoinesQuito Mariscal Sucr

DSM - UIO

DSMUIO

Des Moines

Sat 11/2

2 stops33h 10m

Quito Mariscal Sucr

Fri 11/15

2 stops21h 11m

$500

Des MoinesQuito Mariscal Sucr

DSM - UIO

DSMUIO

Des Moines

Tue 11/5

2 stops21h 46m

Quito Mariscal Sucr

Sat 11/16

2 stops20h 30m

$501

Des MoinesGuayaquil Jose Joaquin de Olmedo

DSM - GYE

DSMGYE

Des Moines

Sat 8/24

2 stops27h 10m

Guayaquil Jose Joaquin de Olmedo

Wed 9/4

2 stops29h 49m

$516

Des MoinesQuito Mariscal Sucr

DSM - UIO

DSMUIO

Des Moines

Sun 11/3

2 stops28h 36m

Quito Mariscal Sucr

Fri 11/15

2 stops13h 48m

$521

Des MoinesGuayaquil Jose Joaquin de Olmedo

DSM - GYE

DSMGYE

Des Moines

Thu 8/22

2 stops18h 10m

Guayaquil Jose Joaquin de Olmedo

Sat 8/31

2 stops29h 49m

$536

Des MoinesQuito Mariscal Sucr

DSM - UIO

DSMUIO

Des Moines

Sun 11/3

2 stops21h 38m

Quito Mariscal Sucr

Sun 11/17

2 stops22h 43m

$541

Des MoinesLima J Chavez Intl

DSM - LIM

DSMLIM

Des Moines

Thu 10/10

2 stops21h 01m

Lima J Chavez Intl

Fri 10/18

2 stops21h 10m

$662

Flights are sorted by cheapest first

Deals found on 7/10

No data available for this route at this time. Please check back soon.

Best time to book a flight from Des Moines to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 11, 2024.
8.0
Very good
9,842 reviews

Overall

8.0

Food

7.4

Boarding

8.2

Crew

8.6

Comfort

7.9

Entertainment

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

8.0
Very good
9,842 reviews
8.0
Very good
9,842 reviews

Overall

8.0

Food

7.4

Boarding

8.2

Crew

8.6

Comfort

7.9

Entertainment

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

7.4
Good
10,000 reviews
8.0
Very good
9,842 reviews

Overall

8.0

Food

7.4

Boarding

8.2

Crew

8.6

Comfort

7.9

Entertainment

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

7.4
Good
3,393 reviews
8.0
Very good
9,842 reviews

Overall

8.0

Food

7.4

Boarding

8.2

Crew

8.6

Comfort

7.9

Entertainment

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

7.3
Good
10,000 reviews
8.0
Very good
9,842 reviews

Overall

8.0

Food

7.4

Boarding

8.2

Crew

8.6

Comfort

7.9

Entertainment

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

6.9
Okay
7,277 reviews
8.0
Very good
9,842 reviews

Overall

8.0

Food

7.4

Boarding

8.2

Crew

8.6

Comfort

7.9

Entertainment

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

Related info for your journey

Find useful and relevant information for your journey from Des Moines to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Des Moines to South America?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to South America.

  • Can I find flights from Des Moines to South America for under $500 on Cheapflights?

    Yes, there are multiple flights from Des Moines to South America for under $500. The cheapest flight booked recently is on American Airlines for just $471, but on average you can expect to pay $546.

  • Are there last-minute flights available from Des Moines to South America for under $1,500?

    There are currently 1+ open flights from Des Moines to South America within the next 7 days for less than $1,500.

  • What are the cheapest airlines to fly from Des Moines to South America one-way?

    For one-way options, check prices for Avianca. According to our data, you can fly for as low as $509. Users have also found prices from $532 and $548 on Delta and United Airlines, respectively.

  • What are the most popular routes from Des Moines to South America?

  • What does DSM to BOG mean?

    These are just IATA (International Air Transport Association) codes. They are used in aviation to identify and differentiate airports. That’s why a Des Moines Airport to Bogotá El Dorado Airport flight would often be abbreviated as a DSM to BOG flight. Lima J Chavez Intl Airport (LIM), Sao Paulo Guarulhos Intl Airport (GRU), Santiago Arturo Merino Benitez Airport (SCL), Medellín Jose Maria Cordova Intl Airport (MDE), Recife Guararapes Intl Airport (REC) are other airports near this flight route and their unique identifiers/IATA codes.

  • Can I find deals for flights from Des Moines to South America that include extra baggage allowance?

    The amount of baggage you can bring on your Des Moines to South America flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Des Moines to South America with specific airlines?

    Yes, Cheapflights allows you to browse and filter Des Moines to South America flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Des Moines to South America that include hotel bookings?

    Yes. In addition to deals on Des Moines to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to South America.

  • Can I find deals for business class flights from Des Moines to South America?

    Yes. Cheapflights offers flight deals from Des Moines to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Des Moines to South America that allow pets onboard?

    Many airlines flying from Des Moines to South America offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Des Moines to South America?

    Yes, you can often find last-minute deals on Des Moines to South America flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Des Moines to South America flight deals updated?

    The Des Moines to South America flight deals you see on this page were last updated on 7/10.

  • What is the cheapest month to book a flight from Des Moines to South America?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to South America (average of $354). Flying from Des Moines to South America in December is currently the most expensive (average of $489). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to South America
See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Des Moines to South America

Discover the top 3 airlines that operate flights from Des Moines to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,800,118 searches. Data last updated July 11, 2024.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$384Average$965FlexibilityNo cancel feeOn-time69%
DeltaCheapest$449Average$1,002FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$457Average$991FlexibilityNo cancel feeOn-time71%

Search flights from Des Moines to South America by cabin class

Find flights from Des Moines to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
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