$420+ Cheap flights from Des Moines (DSM) to Quito (UIO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — UIO
May 29 — Jun 51
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Quito with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Quito
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Best
Last-minute
One-way
Cheapest flights from Des Moines to QuitoExplore the most affordable flight options available from Des Moines to Quito. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
Explore the most affordable flight options available from Des Moines to Quito. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:15 am
DSM
- UIO
1 stop17h 10m
United Airlines
Tue 10/2712:35 am
UIO
- DSM
2 stops13h 36m
United Airlines
Deal found 4/29![United Airlines logo]()
$710
This Justfly.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:27 am
DSM
- UIO
1 stop13h 32m
LATAM Airlines
Thu 6/46:50 pm
UIO
- DSM
2 stops16h 18m
LATAM Airlines
Deal found 4/28![LATAM Airlines logo]()
$734
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:04 pm
DSM
- UIO
2 stops15h 39m
Delta
Thu 6/46:50 pm
UIO
- DSM
2 stops16h 18m
Delta
Deal found 4/28![Delta logo]()
$748
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:56 am
DSM
- UIO
2 stops17h 47m
Delta
Thu 6/46:50 pm
UIO
- DSM
2 stops17h 34m
Delta
Deal found 4/28![Delta logo]()
$758
This eDestinos deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:45 am
DSM
- UIO
1 stop20h 58m
Multiple Airlines
Sun 5/246:50 pm
UIO
- DSM
1 stop28h 34m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$760
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:00 am
DSM
- UIO
2 stops18h 25m
United Airlines
Fri 7/1712:35 am
UIO
- DSM
1 stop13h 45m
United Airlines
Deal found 4/25![United Airlines logo]()
$800
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:55 am
DSM
- UIO
2 stops14h 01m
American Airlines
Wed 6/176:01 am
UIO
- DSM
2 stops14h 42m
American Airlines
Deal found 4/26![American Airlines logo]()
$812
This KAYAK deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:50 pm
DSM
- UIO
2 stops27h 08m
GOL
Wed 7/2911:59 pm
UIO
- DSM
2 stops24h 07m
GOL
Deal found 4/29![GOL logo]()
$828
Best flights from Des Moines to QuitoDiscover carefully curated flight deals from Des Moines to Quito that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
Discover carefully curated flight deals from Des Moines to Quito that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:15 am
DSM
- UIO
1 stop17h 10m
United Airlines
Tue 10/2712:35 am
UIO
- DSM
2 stops13h 36m
United Airlines
Deal found 4/27![United Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:27 am
DSM
- UIO
1 stop13h 32m
Delta
Wed 6/312:59 am
UIO
- DSM
1 stop16h 54m
Delta
Deal found 4/28![Delta logo]()
$743
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:50 am
DSM
- UIO
1 stop18h 09m
American Airlines
Thu 6/46:00 am
UIO
- DSM
2 stops18h 10m
American Airlines
Deal found 4/25![American Airlines logo]()
$748
This eDestinos deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:45 am
DSM
- UIO
1 stop20h 58m
Multiple Airlines
Sun 5/246:30 pm
UIO
- DSM
2 stops28h 54m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$760
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:04 pm
DSM
- UIO
2 stops15h 39m
Delta
Thu 6/46:50 pm
UIO
- DSM
2 stops16h 18m
Delta
Deal found 4/28![Delta logo]()
$748
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:00 am
DSM
- UIO
2 stops18h 25m
United Airlines
Fri 7/1712:35 am
UIO
- DSM
1 stop13h 45m
United Airlines
Deal found 4/25![United Airlines logo]()
$800
Last-minute flights from Des Moines to QuitoDiscover last-minute flight deals from Des Moines to Quito. Data last updated April 29, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Quito. Data last updated April 29, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:27 am
DSM
- UIO
1 stop13h 32m
Delta
Thu 5/1412:59 am
UIO
- DSM
1 stop12h 38m
Delta
Deal found 4/27![Delta logo]()
$941
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:11 am
DSM
- UIO
2 stops15h 21m
American Airlines
Fri 5/1511:40 pm
UIO
- DSM
2 stops18h 55m
American Airlines
Deal found 4/27![American Airlines logo]()
$946
This eDestinos deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:45 am
DSM
- UIO
1 stop20h 58m
Multiple Airlines
Sun 5/246:50 pm
UIO
- DSM
1 stop28h 34m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$760
This Justfly.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:27 am
DSM
- UIO
1 stop13h 32m
LATAM Airlines
Thu 6/46:50 pm
UIO
- DSM
2 stops16h 18m
LATAM Airlines
Deal found 4/28![LATAM Airlines logo]()
$734
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:04 pm
DSM
- UIO
2 stops15h 39m
Delta
Thu 6/46:50 pm
UIO
- DSM
2 stops16h 18m
Delta
Deal found 4/28![Delta logo]()
$748
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:56 am
DSM
- UIO
2 stops17h 47m
Delta
Thu 6/46:50 pm
UIO
- DSM
2 stops17h 34m
Delta
Deal found 4/28![Delta logo]()
$758
One-way flights from Des Moines to QuitoSearch for one-way flight options from Des Moines to Quito. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
Search for one-way flight options from Des Moines to Quito. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:30 am
DSM
- UIO
2 stops17h 28m
American Airlines
Deal found 4/27![American Airlines logo]()
$420
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:41 am
DSM
- UIO
1 stop13h 18m
Delta
Deal found 4/27![Delta logo]()
$549
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:19 pm
DSM
- UIO
3 stops36h 36m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$563
Find flight deals from Des Moines to Quito
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Quito (UIO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $710 (United Airlines) |
One-way from | $420 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Quito that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Des Moines to Quito that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesQuito
DSM - UIO
DSMUIO
Des Moines
Thu 10/22
6:15 am-11:25 pm
1 stop17h 10m
Quito Mariscal Sucr
Tue 10/27
12:35 am-2:11 pm
2 stops13h 36m
$710
Quickest round-trip
Des MoinesQuito
DSM - UIO
DSMUIO
Des Moines
Thu 5/28
5:27 am-6:59 pm
1 stop13h 32m
Quito Mariscal Sucr
Wed 6/3
12:59 am-5:53 pm
1 stop16h 54m
$743
Des MoinesQuito
DSM - UIO
DSMUIO
Des Moines
Wed 5/27
5:50 am-11:59 pm
1 stop18h 09m
Quito Mariscal Sucr
Thu 6/4
6:00 am-12:10 am
2 stops18h 10m
$748
Des MoinesQuito
DSM - UIO
DSMUIO
Des Moines
Wed 5/27
1:04 pm-4:43 am
2 stops15h 39m
Quito Mariscal Sucr
Thu 6/4
6:50 pm-11:08 am
2 stops16h 18m
$748
Des MoinesQuito
DSM - UIO
DSMUIO
Des Moines
Thu 5/14
7:45 am-4:43 am
1 stop20h 58m
Quito Mariscal Sucr
Sun 5/24
6:30 pm-11:24 pm
2 stops28h 54m
$760
Des MoinesQuito
DSM - UIO
DSMUIO
Des Moines
Tue 7/7
5:00 am-11:25 pm
2 stops18h 25m
Quito Mariscal Sucr
Fri 7/17
12:35 am-2:20 pm
1 stop13h 45m
$800
Cheapest one-way
Des MoinesQuito
DSM - UIO
DSMUIO
Des Moines
Wed 7/22
6:30 am-11:58 pm
2 stops17h 28m
$420
Quickest one-way
Des MoinesQuito
DSM - UIO
DSMUIO
Des Moines
Wed 7/22
5:41 am-6:59 pm
1 stop13h 18m
$549
Des MoinesQuito
DSM - UIO
DSMUIO
Des Moines
Wed 7/22
2:19 pm-2:55 am
3 stops36h 36m
$563
Sorted by cheapest first
Compare providers for flights from Des Moines to Quito
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Quito in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Quito flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Quito flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Quito flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Quito flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Quito flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Quito
Have a flexible travel schedule? Discover the best time to fly to Quito from Des Moines with our price prediction graph.
DSM-UIO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Quito
Get insights into the airlines that provide service to Quito. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Quito. Reviews last updated April 29, 2026.
Read reviews from past customers who have flown Delta and United Airlines from Des Moines to Quito. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Entertainment
7.8
Crew
8.5
Comfort
7.9
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Food
7.2
Entertainment
7.8
Crew
8.5
Comfort
7.9
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Food
7.2
Entertainment
7.8
Crew
8.5
Comfort
7.9
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Quito. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Find flights from Des Moines to Quito, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Quito flights
Browse other Des Moines and Quito flight options. Last updated on April 29, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Popular flight searches
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Other flights to Quito
Explore flights to Quito departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Top 2 airlines flying from Des Moines to Quito
Discover the top 2 airlines that operate flights from Des Moines to Quito. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$643 | Average$755 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$647 | Average$685 | FlexibilityNo cancel fee | On-time69% |