$429+ Cheap flights from Des Moines (DSM) to Quito (UIO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — UIO
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Quito with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Quito
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to QuitoExplore the most affordable flight options available from Des Moines to Quito. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Des Moines to Quito. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This LATAM Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:17 pm -
2 stops25h 35m
Tue 11/248:55 am -
2 stops14h 40m
Deal found 9/3![LATAM Airlines logo]()
$771
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:16 pm -
1 stop30h 20m
Tue 11/246:31 am -
1 stop18h 13m
Deal found 9/3![American Airlines logo]()
$786
Best flights from Des Moines to QuitoDiscover carefully curated flight deals from Des Moines to Quito that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Des Moines to Quito that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This LATAM Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:17 pm -
2 stops25h 35m
Tue 11/248:55 am -
2 stops14h 40m
Deal found 9/3![LATAM Airlines logo]()
$771
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:16 pm -
1 stop30h 20m
Tue 11/246:31 am -
1 stop18h 13m
Deal found 9/3![American Airlines logo]()
$786
Last-minute flights from Des Moines to QuitoDiscover last-minute flight deals from Des Moines to Quito. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Quito. Data last updated September 7, 2026 and is based on user searches.
This LATAM Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:27 am -
1 stop9h 58m
Sun 11/812:55 am -
1 stop18h 12m
Deal found 9/7![LATAM Airlines logo]()
$771
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:43 pm -
2 stops28h 47m
Sun 11/81:35 am -
2 stops16h 53m
Deal found 9/7![United Airlines logo]()
$776
One-way flights from Des Moines to QuitoSearch for one-way flight options from Des Moines to Quito. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Des Moines to Quito. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:42 pm -
3 stops50h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$429
This BusinessClass deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:55 pm -
2 stops25h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Copa Airlines logo]()
$430
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:45 am -
1 stop13h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Delta logo]()
$455
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:45 am -
1 stop13h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Delta logo]()
$485
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:02 pm -
1 stop8h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![United Airlines logo]()
$561
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:46 pm -
3 stops50h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$1,520
Find flight deals from Des Moines to Quito
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Quito (UIO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $771 (LATAM Airlines) |
One-way from | $429 (Kiwi.com) |
Popular in | June |
Cheapest in | February |
Average price | $677 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Quito that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Des Moines to Quito that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Wed 9/30
2:42 pm-5:18 pm
3 stops50h 36m
Quito Mariscal Sucr
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$429
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Wed 9/30
6:55 pm-8:41 pm
2 stops25h 46m
Quito Mariscal Sucr
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$430
Quickest round-trip
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Wed 9/30
5:45 am-6:59 pm
1 stop13h 14m
Quito Mariscal Sucr
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$455
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Wed 9/30
5:45 am-7:05 pm
2 stops13h 20m
Quito Mariscal Sucr
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$465
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Wed 9/16
6:54 pm-11:00 pm
2 stops28h 06m
Quito Mariscal Sucr
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$485
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Sat 11/14
4:17 pm-6:52 pm
2 stops25h 35m
Quito Mariscal Sucr
Tue 11/24
8:55 am-10:35 pm
2 stops14h 40m
$771
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Sat 11/14
3:16 pm-10:36 pm
1 stop30h 20m
Quito Mariscal Sucr
Tue 11/24
6:31 am-11:44 pm
1 stop18h 13m
$786
Sorted by cheapest first
Compare providers for flights from Des Moines to Quito
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Quito in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Quito flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Quito flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Quito flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Quito flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Quito flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Quito
Have a flexible travel schedule? Discover the best time to fly to Quito from Des Moines with our price prediction graph.
DSM-UIO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Quito
Get insights into the airlines that provide service to Quito. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Quito. Reviews last updated September 7, 2026.
Read reviews from past customers who have flown Delta from Des Moines to Quito. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Quito. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Des Moines and Quito flights
Browse other Des Moines and Quito flight options. Last updated on September 7, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Popular flight searches
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Other flights to Quito
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Top airline flying from Des Moines to Quito
Discover the top airline that operate flights from Des Moines to Quito. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$643 | Average$863 | FlexibilityNo cancel fee | On-timeN/A |