$311+ Cheap flights from Des Moines (DSM) to Quito (UIO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — UIO
Nov 26 — Dec 31
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Des Moines to Quito with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Quito
Cheapest
Best
One-way
Cheapest flights from Des Moines to QuitoExplore the most affordable flight options available from Des Moines to Quito. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
Explore the most affordable flight options available from Des Moines to Quito. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:07 am -
2 stops15h 31m
Wed 12/166:45 am -
1 stop17h 14m
Deal found 10/25![American Airlines logo]()
$848
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:56 pm -
1 stop8h 34m
Tue 12/151:35 am -
1 stop13h 40m
Deal found 10/25![United Airlines logo]()
$917
Best flights from Des Moines to QuitoDiscover carefully curated flight deals from Des Moines to Quito that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
Discover carefully curated flight deals from Des Moines to Quito that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:24 am -
2 stops16h 14m
Tue 12/1512:55 am -
2 stops13h 40m
Deal found 10/25![American Airlines logo]()
$848
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:56 pm -
1 stop8h 34m
Tue 12/151:35 am -
1 stop13h 40m
Deal found 10/25![United Airlines logo]()
$917
This LATAM Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2011:04 am -
2 stops11h 56m
Thu 4/2212:59 am -
1 stop16h 43m
Deal found 10/26![LATAM Airlines logo]()
$948
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/205:00 am -
2 stops18h 25m
Thu 4/2212:35 am -
2 stops22h 26m
Deal found 10/22![United Airlines logo]()
$952
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:00 am -
2 stops16h 55m
Fri 1/1512:55 am -
1 stop13h 02m
Deal found 10/26![American Airlines logo]()
$968
One-way flights from Des Moines to QuitoSearch for one-way flight options from Des Moines to Quito. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
Search for one-way flight options from Des Moines to Quito. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:00 am -
2 stops28h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$311
This KAYAK deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:45 pm -
2 stops28h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Copa Airlines logo]()
$473
This KAYAK deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/258:00 am -
2 stops14h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Copa Airlines logo]()
$484
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/258:00 am -
1 stop15h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![United Airlines logo]()
$501
This LATAM Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/111:27 am -
1 stop8h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![LATAM Airlines logo]()
$525
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:00 am -
1 stop14h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![American Airlines logo]()
$550
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:00 am -
3 stops32h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$553
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:45 pm -
3 stops44h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$580
This Faresmojo deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:39 am -
1 stop14h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![JetBlue logo]()
$624
Find flight deals from Des Moines to Quito
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Quito (UIO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $848 (American Airlines) |
One-way from | $311 (Kiwi.com) |
Popular in | June |
Cheapest in | February |
Average price | $917 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Quito that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
Use the filters below to find and compare flights from Des Moines to Quito that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Mon 1/25
8:00 am-11:34 pm
2 stops14h 34m
Quito Mariscal Sucr
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$484
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Mon 1/25
8:00 am-12:30 am
1 stop15h 30m
Quito Mariscal Sucr
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$501
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Sun 11/1
11:27 am-9:25 pm
1 stop8h 58m
Quito Mariscal Sucr
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$525
Quickest round-trip
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Mon 11/9
11:36 am-9:25 pm
1 stop8h 49m
Quito Mariscal Sucr
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$525
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Mon 11/2
6:00 am-9:25 pm
2 stops14h 25m
Quito Mariscal Sucr
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$525
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Wed 12/9
5:24 am-10:38 pm
2 stops16h 14m
Quito Mariscal Sucr
Tue 12/15
12:55 am-1:35 pm
2 stops13h 40m
$848
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Wed 12/9
2:56 pm-12:30 am
1 stop8h 34m
Quito Mariscal Sucr
Tue 12/15
1:35 am-2:15 pm
1 stop13h 40m
$917
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Tue 4/20
11:04 am-11:00 pm
2 stops11h 56m
Quito Mariscal Sucr
Thu 4/22
12:59 am-5:42 pm
1 stop16h 43m
$948
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Tue 4/20
5:00 am-11:25 pm
2 stops18h 25m
Quito Mariscal Sucr
Thu 4/22
12:35 am-11:01 pm
2 stops22h 26m
$952
Des MoinesQuito
DSM Des Moines - UIO Quito Mariscal Sucr
DSMUIO
Des Moines
Thu 1/7
6:00 am-11:55 pm
2 stops16h 55m
Quito Mariscal Sucr
Fri 1/15
12:55 am-12:57 pm
1 stop13h 02m
$968
Sorted by cheapest first
Compare providers for flights from Des Moines to Quito
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Quito in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Quito flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Quito flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Quito flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Quito flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Quito flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Quito
Have a flexible travel schedule? Discover the best time to fly to Quito from Des Moines with our price prediction graph.
DSM-UIO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Quito
Get insights into the airlines that provide service to Quito. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Quito. Reviews last updated October 27, 2026.
Read reviews from past customers who have flown Delta from Des Moines to Quito. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.8
Food
7.2
Overall
7.8
Crew
8.5
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Comfort
7.8
Food
7.2
Overall
7.8
Crew
8.5
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Quito. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Complete your trip
Flights by cabin class
Other flight options
Other flights from Des Moines
Popular flights
Quito flight routes
Complete your trip
Complete your trip to Quito by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Quito by cabin class
Find flights from Des Moines to Quito, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Quito flights
Browse other Des Moines and Quito flight options. Last updated on October 27, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on October 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Quito
Explore flights to Quito departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 27, 2026.
Top airline flying from Des Moines to Quito
Discover the top airline that operate flights from Des Moines to Quito. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$643 | Average$863 | FlexibilityNo cancel fee | On-timeN/A |