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$243+ Cheap flights from Quito (UIO) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — SCL
Jun 23 — Jun 301
Mon 6/23
Mon 6/30
1 adult, Economy
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Cheapflights Tip: The best prices from Quito Mariscal Sucr to Santiago Arturo Merino Benitez are usually found in April or May, booked 81 days in advance, depart on a Monday or Friday and return on a Friday

Cheap flight deals from Quito to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Quito (UIO) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 18, 2025.

Round-trip from

$426
(Booking.com)

One-way from

$287
(Copa Airlines)

Popular in

February

Cheapest in

April

Average price

$344
From Quito Mariscal Sucr to Santiago Arturo Merino Benitez
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One-way flight from Quito Mariscal Sucr to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 9% potential increase in price ($36 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Quito to Santiago

Cheapest flights from Quito to Santiago
Explore the most affordable flight options available from Quito to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2025.

This Trip.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/104:41 pmUIO - SCL
1 stop10h 20mJetSMART
Sun 10/195:51 amSCL - UIO
1 stop12h 18mJetSMART
Deal found 6/17$375
This Booking.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/104:41 pmUIO - SCL
1 stop10h 20mMultiple Airlines
Sat 10/1812:55 amSCL - UIO
1 stop15h 45mMultiple Airlines
Deal found 6/17$395
This Priceline deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/92:30 amUIO - SCL
1 stop9h 55mAvianca
Sat 10/1812:55 amSCL - UIO
1 stop15h 45mAvianca
Deal found 6/17$434
This Copa Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/183:22 amUIO - SCL
1 stop18h 46mCopa Airlines
Sat 11/224:19 amSCL - UIO
1 stop15h 20mCopa Airlines
Deal found 6/16$463
This LATAM Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/308:15 pmUIO - SCL
2 stops11h 59mLATAM Airlines
Tue 7/14:55 pmSCL - UIO
1 stop10h 09mLATAM Airlines
Deal found 6/18$469

Cheapflights Fare Finder

Customize your flight search to find flights from Quito to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2025.
Use the filters below to find and compare flights from Quito to Santiago that are best for you.

Fly from

Quito

Fly to

Santiago

Route

Depart

Return

Price

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 10/10

4:41 pm-5:01 am

1 stop10h 20m

Santiago Arturo Merino Benitez

Sun 10/19

5:51 am-4:09 pm

1 stop12h 18m

$375

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 10/10

4:41 pm-5:01 am

1 stop10h 20m

Santiago Arturo Merino Benitez

Sat 10/18

12:55 am-2:40 pm

1 stop15h 45m

$395

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Thu 10/9

2:30 am-2:25 pm

1 stop9h 55m

Santiago Arturo Merino Benitez

Sat 10/18

12:55 am-2:40 pm

1 stop15h 45m

$434

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Tue 11/18

3:22 am-12:08 am

1 stop18h 46m

Santiago Arturo Merino Benitez

Sat 11/22

4:19 am-5:39 pm

1 stop15h 20m

$463

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Mon 6/30

8:15 pm-9:14 am

2 stops11h 59m

Santiago Arturo Merino Benitez

Tue 7/1

4:55 pm-2:04 am

1 stop10h 09m

$469

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 10/22

8:38 pm-2:25 pm

2 stops15h 47m

$243

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 10/22

6:59 am-10:25 am

3 stops25h 26m

$289

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sun 7/27

6:10 am-8:38 pm

1 stop13h 28m

$302

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Mon 7/7

3:07 am-11:08 pm

1 stop19h 01m

$471

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/17

Best time to book a flight from Quito to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Quito with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Quito to Santiago

How far ahead should I book a flight from Quito to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Quito to Santiago. Price data was last updated on June 13, 2025.

The price you pay for your flight from Quito to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 81 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Quito to Santiago?

Currently, April is the cheapest month in which you can book a flight from Quito to Santiago (average of $752). Flying from Quito to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from UIO to SCL?

Find hourly flight availability from Quito to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 18, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 9% on flights from Quito to Santiago by exploring options for tickets at noon.

What is the cheapest day to fly from Quito to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Quito to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Quito to Santiago flight should consider departing on Monday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated June 18, 2025.
To help decide which airline to fly from Quito to Santiago, see what other customers have to say about LATAM Airlines, Copa Airlines and Avianca. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,787 reviews

Entertainment

7.0

Boarding

7.6

Food

6.7

Crew

8.1

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
LATAM Airlines
7.5
Good
1,787 reviews
LATAM Airlines
7.5
Good
1,787 reviews

Entertainment

7.0

Boarding

7.6

Food

6.7

Crew

8.1

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Copa Airlines
7.5
Good
1,455 reviews
LATAM Airlines
7.5
Good
1,787 reviews

Entertainment

7.0

Boarding

7.6

Food

6.7

Crew

8.1

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Avianca
6.7
Okay
2,350 reviews
LATAM Airlines
7.5
Good
1,787 reviews

Entertainment

7.0

Boarding

7.6

Food

6.7

Crew

8.1

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
JetSMART
6.6
Okay
197 reviews
LATAM Airlines
7.5
Good
1,787 reviews

Entertainment

7.0

Boarding

7.6

Food

6.7

Crew

8.1

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Related info for your journey

Find useful and relevant information for your journey from Quito to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Quito to Santiago round-trip?

    Currently priced at $446, Avianca will fly you from Quito to Santiago and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from JetSMART and LATAM Airlines - these airlines can fly you to your destination from $453 and $469, respectively.

  • What are the cheapest airlines to fly from Quito to Santiago one-way?

    The cheapest airlines for a one-way flight from Quito to Santiago are Copa Airlines ($287), Avianca ($290), and LATAM Airlines ($302).

  • Can I find deals for flights from Quito to Santiago that include hotel bookings?

    Yes. In addition to deals on Quito to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Quito to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Quito to Santiago.

  • Can I find deals for business class flights from Quito to Santiago?

    Yes. Cheapflights offers flight deals from Quito to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Quito to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Quito to Santiago (average of $752). Flying from Quito to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Quito to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Guayaquil to Santiago flights

Top 4 airlines flying from Quito to Santiago

Discover the top 4 airlines that operate flights from Quito to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$168Average$419FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$183Average$563FlexibilityNo cancel feeOn-time70%
JetSMARTCheapest$214Average$334FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$362Average$472FlexibilityNo cancel feeOn-time81%

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