$201+ Cheap flights from Quito (UIO) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — SCL
Oct 1 — Oct 81
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Quito to Santiago
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Cheapest flights from Quito to SantiagoExplore the most affordable flight options available from Quito to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
Explore the most affordable flight options available from Quito to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
This Booking.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:48 pm -
1 stop10h 00m
Fri 10/306:07 am -
1 stop11h 57m
Deal found 8/30![JetSMART logo]()
$320
This Booking.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:48 pm -
1 stop10h 20m
Sun 11/16:07 am -
1 stop11h 57m
Deal found 8/30![JetSMART logo]()
$321
This Booking.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/224:50 pm -
1 stop10h 13m
Fri 11/276:07 am -
1 stop11h 57m
Deal found 8/30![JetSMART logo]()
$322
This Booking.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:48 pm -
1 stop10h 00m
Sun 10/256:12 am -
1 stop11h 51m
Deal found 8/27![JetSMART logo]()
$323
This JetSMART deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:50 pm -
1 stop10h 13m
Sun 11/226:07 am -
1 stop11h 57m
Deal found 8/31![JetSMART logo]()
$325
This Booking.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:50 pm -
1 stop10h 18m
Mon 11/26:07 am -
1 stop11h 57m
Deal found 8/30![JetSMART logo]()
$329
This FlightHub deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:50 pm -
1 stop10h 18m
Wed 11/186:07 am -
1 stop11h 57m
Deal found 8/30![JetSMART logo]()
$345
This JetSMART deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/224:50 pm -
1 stop10h 13m
Wed 12/26:07 am -
1 stop11h 57m
Deal found 8/30![JetSMART logo]()
$346
This JetSMART deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:50 pm -
1 stop10h 13m
Fri 11/276:07 am -
1 stop11h 57m
Deal found 8/28![JetSMART logo]()
$347
This CheapOair deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:50 pm -
1 stop10h 13m
Sun 11/88:13 am -
1 stop16h 47m
Deal found 8/31![Multiple Airlines logo]()
$348
This CheapOair deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:50 pm -
1 stop10h 13m
Fri 11/136:07 am -
1 stop11h 57m
Deal found 8/27![JetSMART logo]()
$350
This CheapOair deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:50 pm -
1 stop10h 13m
Fri 11/136:07 am -
1 stop11h 57m
Deal found 8/26![JetSMART logo]()
$352
Best flights from Quito to SantiagoDiscover carefully curated flight deals from Quito to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
Discover carefully curated flight deals from Quito to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
This JetSMART deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:50 pm -
1 stop10h 13m
Fri 11/276:07 am -
1 stop11h 57m
Deal found 8/31![JetSMART logo]()
$325
This JetSMART deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:50 pm -
1 stop10h 13m
Sun 11/226:07 am -
1 stop11h 57m
Deal found 8/31![JetSMART logo]()
$325
This JetSMART deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:50 pm -
1 stop10h 13m
Wed 11/116:07 am -
1 stop11h 57m
Deal found 8/31![JetSMART logo]()
$363
This JetSMART deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:50 pm -
1 stop10h 13m
Tue 12/110:12 pm -
1 stop19h 52m
Deal found 8/30![JetSMART logo]()
$383
This JetSMART deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:50 pm -
1 stop10h 13m
Wed 11/116:07 am -
1 stop11h 57m
Deal found 8/26![JetSMART logo]()
$383
This JetSMART deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:50 pm -
1 stop10h 13m
Wed 11/116:07 am -
1 stop11h 57m
Deal found 8/26![JetSMART logo]()
$383
This JetSMART deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:50 pm -
1 stop10h 13m
Wed 12/26:07 am -
1 stop11h 57m
Deal found 8/30![JetSMART logo]()
$383
This JetSMART deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:50 pm -
1 stop10h 13m
Mon 11/236:07 am -
1 stop11h 57m
Deal found 8/29![JetSMART logo]()
$383
This JetSMART deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:50 pm -
1 stop10h 13m
Mon 11/236:07 am -
1 stop11h 57m
Deal found 8/29![JetSMART logo]()
$383
This Priceline deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:50 pm -
2 stops29h 46m
Mon 11/26:07 am -
1 stop11h 57m
Deal found 8/30![JetSMART logo]()
$426
Last-minute flights from Quito to SantiagoDiscover last-minute flight deals from Quito to Santiago. Data last updated September 1, 2026 and is based on user searches.
Discover last-minute flight deals from Quito to Santiago. Data last updated September 1, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:48 pm -
1 stop10h 15m
Fri 9/256:07 am -
1 stop11h 56m
Deal found 8/26![JetSMART logo]()
$405
This JetSMART deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:48 pm -
1 stop10h 15m
Sun 11/16:07 am -
1 stop11h 57m
Deal found 8/27![JetSMART logo]()
$448
This Booking.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/164:48 pm -
1 stop10h 25m
Fri 9/256:07 am -
1 stop11h 56m
Deal found 8/27![JetSMART logo]()
$429
This CheapOair deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/164:48 pm -
1 stop10h 25m
Wed 9/235:47 am -
1 stop12h 16m
Deal found 8/30![JetSMART logo]()
$436
This Trip.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1910:05 am -
1 stop12h 24m
Sun 9/276:07 am -
1 stop11h 56m
Deal found 8/27![Multiple Airlines logo]()
$454
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:45 pm -
2 stops21h 40m
Fri 9/256:07 am -
1 stop11h 56m
Deal found 8/26![Multiple Airlines logo]()
$452
This Booking.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/274:48 pm -
1 stop10h 15m
Sun 10/46:12 am -
1 stop11h 51m
Deal found 8/30![JetSMART logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/304:48 pm -
1 stop10h 25m
Tue 10/68:33 pm -
1 stop21h 30m
Deal found 8/30![Multiple Airlines logo]()
$407
This Mytrip deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/304:48 pm -
1 stop10h 25m
Tue 10/67:12 pm -
2 stops22h 51m
Deal found 8/30![JetSMART logo]()
$431
This CheapOair deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/304:48 pm -
1 stop10h 25m
Tue 10/1312:05 am -
1 stop13h 35m
Deal found 8/29![Multiple Airlines logo]()
$440
One-way flights from Quito to SantiagoSearch for one-way flight options from Quito to Santiago. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
Search for one-way flight options from Quito to Santiago. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:48 pm -
1 stop10h 25m
Deal found 8/28![JetSMART logo]()
$201
This Priceline deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:48 pm -
1 stop10h 00m
Deal found 8/30![JetSMART logo]()
$203
This JetSMART deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/274:48 pm -
1 stop10h 15m
Deal found 8/29![JetSMART logo]()
$205
This CheapOair deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:50 pm -
1 stop10h 13m
Deal found 8/28![JetSMART logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:48 pm -
1 stop10h 20m
Deal found 8/30![JetSMART logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:48 pm -
1 stop10h 20m
Deal found 8/27![JetSMART logo]()
$235
This JetSMART deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:48 pm -
1 stop10h 25m
Deal found 8/27![JetSMART logo]()
$240
This JetSMART deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:50 pm -
1 stop10h 18m
Deal found 8/27![JetSMART logo]()
$244
Find flight deals from Quito to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Quito (UIO) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $320 (Booking.com) |
One-way from | $201 (Kiwi.com) |
Popular in | February |
Cheapest in | June |
Average price | $414 |
Cheapflights Fare Finder
Customize your flight search to find flights from Quito to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
Use the filters below to find and compare flights from Quito to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Fri 11/20
4:50 pm-5:03 am
1 stop10h 13m
Santiago Arturo Merino Benitez
Fri 11/27
6:07 am-4:04 pm
1 stop11h 57m
$325
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Sun 11/15
4:50 pm-5:03 am
1 stop10h 13m
Santiago Arturo Merino Benitez
Sun 11/22
6:07 am-4:04 pm
1 stop11h 57m
$325
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Wed 11/4
4:50 pm-5:03 am
1 stop10h 13m
Santiago Arturo Merino Benitez
Wed 11/11
6:07 am-4:04 pm
1 stop11h 57m
$363
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Fri 11/20
4:50 pm-5:03 am
1 stop10h 13m
Santiago Arturo Merino Benitez
Tue 12/1
10:12 pm-4:04 pm
1 stop19h 52m
$383
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Fri 11/6
4:50 pm-5:03 am
1 stop10h 13m
Santiago Arturo Merino Benitez
Wed 11/11
6:07 am-4:04 pm
1 stop11h 57m
$383
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Sun 11/8
4:50 pm-5:03 am
1 stop10h 13m
Santiago Arturo Merino Benitez
Wed 11/11
6:07 am-4:04 pm
1 stop11h 57m
$383
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Fri 11/20
4:50 pm-5:03 am
1 stop10h 13m
Santiago Arturo Merino Benitez
Wed 12/2
6:07 am-4:04 pm
1 stop11h 57m
$383
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Fri 11/13
4:50 pm-5:03 am
1 stop10h 13m
Santiago Arturo Merino Benitez
Mon 11/23
6:07 am-4:04 pm
1 stop11h 57m
$383
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Mon 11/9
4:50 pm-5:03 am
1 stop10h 13m
Santiago Arturo Merino Benitez
Mon 11/23
6:07 am-4:04 pm
1 stop11h 57m
$383
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Wed 10/28
4:50 pm-12:36 am
2 stops29h 46m
Santiago Arturo Merino Benitez
Mon 11/2
6:07 am-4:04 pm
1 stop11h 57m
$426
Showing 1-10 of 19 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Quito-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Quito-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Quito-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Quito-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Quito-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Quito to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Quito with our price prediction graph.
UIO-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Quito to Santiago
How far ahead should I book a flight from Quito to Santiago?
The price you pay for your flight from Quito to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 76 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Quito to Santiago?
Currently, June is the cheapest month in which you can book a flight from Quito to Santiago (average of $361). Flying from Quito to Santiago in February is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Quito to Santiago?
Airfare is typical for this route at the moment.
Quito to Santiago flights typically cost between $260 and $498 in October.The cheapest round-trip price found within the last 5 days was $320 on JetSMART (Oct 19-Oct 30).
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 1, 2026.
Read reviews from past customers who have flown Copa Airlines,LATAM Airlines, andJetSMART from Quito to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Overall
7.6
Food
6.9
Crew
8.1
Comfort
7.4
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Entertainment
6.8
Overall
7.6
Food
6.9
Crew
8.1
Comfort
7.4
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Entertainment
6.8
Overall
7.6
Food
6.9
Crew
8.1
Comfort
7.4
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Entertainment
6.8
Overall
7.6
Food
6.9
Crew
8.1
Comfort
7.4
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Entertainment
6.8
Overall
7.6
Food
6.9
Crew
8.1
Comfort
7.4
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
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Quito and Santiago flights
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Top 4 airlines flying from Quito to Santiago
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$193 | Average$396 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$221 | Average$578 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$232 | Average$547 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$275 | Average$556 | FlexibilityNo cancel fee | On-time70% |