$219+ Cheap flights from Quito (UIO) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/30. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — SCL
Nov 5 — Nov 121
Round-trip
1 adult, Economy
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Find cheap flights from Quito to Santiago with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Quito to Santiago
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Cheapest flights from Quito to SantiagoExplore the most affordable flight options available from Quito to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 6, 2026.
Explore the most affordable flight options available from Quito to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 6, 2026.
This JetSMART deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:50 pm -
1 stop10h 15m
Fri 11/136:07 am -
1 stop11h 58m
Deal found 10/5![JetSMART logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:50 pm -
1 stop10h 15m
Mon 12/76:07 am -
1 stop11h 58m
Deal found 10/4![JetSMART logo]()
$373
This Booking.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:50 pm -
1 stop10h 15m
Fri 11/66:07 am -
1 stop11h 58m
Deal found 10/2![JetSMART logo]()
$380
This CheapOair deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:50 pm -
1 stop10h 15m
Mon 11/166:07 am -
1 stop11h 58m
Deal found 10/2![JetSMART logo]()
$387
This JetSMART deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/224:50 pm -
1 stop10h 15m
Fri 11/276:07 am -
1 stop11h 58m
Deal found 10/5![JetSMART logo]()
$393
This JetSMART deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:50 pm -
1 stop10h 15m
Sun 12/66:07 am -
1 stop11h 58m
Deal found 10/2![JetSMART logo]()
$397
This CheapOair deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:48 pm -
1 stop10h 25m
Sat 1/1612:32 pm -
1 stop29h 32m
Deal found 10/3![JetSMART logo]()
$403
This Booking.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:50 pm -
1 stop10h 15m
Wed 11/256:07 am -
1 stop11h 58m
Deal found 10/4![JetSMART logo]()
$404
This CheapOair deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/112:03 pm -
1 stop10h 18m
Sun 11/86:07 am -
1 stop11h 58m
Deal found 10/5![Multiple Airlines logo]()
$406
Best flights from Quito to SantiagoDiscover carefully curated flight deals from Quito to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 6, 2026.
Discover carefully curated flight deals from Quito to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 6, 2026.
This JetSMART deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:50 pm -
1 stop10h 15m
Fri 11/136:07 am -
1 stop11h 58m
Deal found 10/5![JetSMART logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:50 pm -
1 stop10h 15m
Thu 11/128:13 am -
1 stop16h 47m
Deal found 10/5![Multiple Airlines logo]()
$364
This JetSMART deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/224:50 pm -
1 stop10h 15m
Fri 11/276:07 am -
1 stop11h 58m
Deal found 10/5![JetSMART logo]()
$393
This JetSMART deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:50 pm -
1 stop10h 15m
Sun 12/66:07 am -
1 stop11h 58m
Deal found 10/2![JetSMART logo]()
$397
This JetSMART deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:50 pm -
1 stop10h 15m
Mon 1/186:07 am -
1 stop11h 57m
Deal found 10/5![JetSMART logo]()
$462
This JetSMART deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/24:50 pm -
1 stop10h 15m
Mon 12/76:07 am -
1 stop11h 58m
Deal found 10/1![JetSMART logo]()
$509
This FlightHub deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:48 pm -
1 stop9h 45m
Mon 11/26:07 am -
1 stop11h 58m
Deal found 10/3![JetSMART logo]()
$543
This JetSMART deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:48 pm -
1 stop10h 15m
Sun 11/86:07 am -
1 stop11h 58m
Deal found 10/5![JetSMART logo]()
$563
Last-minute flights from Quito to SantiagoDiscover last-minute flight deals from Quito to Santiago. Data last updated October 6, 2026 and is based on user searches.
Discover last-minute flight deals from Quito to Santiago. Data last updated October 6, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:48 pm -
1 stop10h 25m
Sat 1/1612:32 pm -
1 stop29h 32m
Deal found 10/3![JetSMART logo]()
$403
This CheapOair deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/112:03 pm -
1 stop10h 18m
Sun 11/86:07 am -
1 stop11h 58m
Deal found 10/5![Multiple Airlines logo]()
$406
This Booking.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:50 pm -
1 stop10h 15m
Fri 11/66:07 am -
1 stop11h 58m
Deal found 10/2![JetSMART logo]()
$380
This JetSMART deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:50 pm -
1 stop10h 15m
Fri 11/136:07 am -
1 stop11h 58m
Deal found 10/5![JetSMART logo]()
$342
This CheapOair deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:50 pm -
1 stop10h 15m
Mon 11/166:07 am -
1 stop11h 58m
Deal found 10/2![JetSMART logo]()
$387
This Booking.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:50 pm -
1 stop10h 15m
Wed 11/256:07 am -
1 stop11h 58m
Deal found 10/4![JetSMART logo]()
$404
This JetSMART deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/224:50 pm -
1 stop10h 15m
Fri 11/276:07 am -
1 stop11h 58m
Deal found 10/5![JetSMART logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:50 pm -
1 stop10h 15m
Mon 12/76:07 am -
1 stop11h 58m
Deal found 10/4![JetSMART logo]()
$373
This JetSMART deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:50 pm -
1 stop10h 15m
Sun 12/66:07 am -
1 stop11h 58m
Deal found 10/2![JetSMART logo]()
$397
One-way flights from Quito to SantiagoSearch for one-way flight options from Quito to Santiago. Find affordable one-way fares based on user searches. Data last updated October 6, 2026.
Search for one-way flight options from Quito to Santiago. Find affordable one-way fares based on user searches. Data last updated October 6, 2026.
This FlightHub deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/304:50 pm -
1 stop10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![JetSMART logo]()
$219
This Booking.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:50 pm -
1 stop10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![JetSMART logo]()
$221
This Booking.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:50 pm -
1 stop16h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![JetSMART logo]()
$223
This JetSMART deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/274:50 pm -
1 stop10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![JetSMART logo]()
$225
This JetSMART deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:48 pm -
1 stop10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![JetSMART logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:50 pm -
1 stop10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![JetSMART logo]()
$266
This Booking.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/164:50 pm -
1 stop10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![JetSMART logo]()
$273
This JetSMART deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:50 pm -
1 stop10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![JetSMART logo]()
$274
This Booking.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/144:50 pm -
1 stop10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![JetSMART logo]()
$275
This JetSMART deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/154:50 pm -
1 stop10h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![JetSMART logo]()
$276
Find flight deals from Quito to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Quito (UIO) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $373 (Kiwi.com) |
One-way from | $219 (FlightHub) |
Popular in | February |
Cheapest in | April |
Average price | $430 |
Good one-way deal | $335 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Quito to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 6, 2026.
Use the filters below to find and compare flights from Quito to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Fri 11/27
4:50 pm-5:05 am
1 stop10h 15m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$225
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Fri 10/23
4:48 pm-5:03 am
1 stop10h 15m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$245
Quickest round-trip
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Sun 10/25
4:48 pm-4:33 am
1 stop9h 45m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$245
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Wed 12/16
4:50 pm-5:05 am
1 stop10h 15m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$273
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Mon 11/30
4:50 pm-5:05 am
1 stop10h 15m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$274
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Fri 12/25
4:50 pm-6:01 pm
1 stop23h 11m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$278
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Mon 10/26
4:48 pm-12:36 am
2 stops29h 48m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$316
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Tue 11/17
6:40 pm-6:00 pm
2 stops21h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$326
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Fri 11/6
4:50 pm-5:05 am
1 stop10h 15m
Santiago Arturo Merino Benitez
Fri 11/13
6:07 am-4:05 pm
1 stop11h 58m
$342
QuitoSantiago
UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez
UIOSCL
Quito Mariscal Sucr
Wed 11/11
4:50 pm-5:05 am
1 stop10h 15m
Santiago Arturo Merino Benitez
Thu 11/12
8:13 am-11:00 pm
1 stop16h 47m
$364
Showing 1-10 of 16 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Quito-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Quito-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Quito-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Quito-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Quito-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Quito to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Quito with our price prediction graph.
UIO-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Quito to Santiago
How far ahead should I book a flight from Quito to Santiago?
The price you pay for your flight from Quito to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 68 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Quito to Santiago?
Currently, April is the cheapest month in which you can book a flight from Quito to Santiago (average of $362). Flying from Quito to Santiago in February is currently the most expensive (average of $529). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Quito to Santiago?
Airfare is typical for this route at the moment.
Quito to Santiago flights typically cost between $268 and $563 in November.The cheapest round-trip price found within the last 5 days was $339 on JetSMART (Nov 18-Nov 23).
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated October 6, 2026.
Read reviews from past customers who have flown Copa Airlines,LATAM Airlines, andJetSMART from Quito to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Overall
7.6
Boarding
7.8
Entertainment
6.9
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Overall
7.6
Boarding
7.8
Entertainment
6.9
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Overall
7.6
Boarding
7.8
Entertainment
6.9
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Overall
7.6
Boarding
7.8
Entertainment
6.9
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Overall
7.6
Boarding
7.8
Entertainment
6.9
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Quito to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Find flights from Quito to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Quito and Santiago flights
Browse other Quito and Santiago flight options. Last updated on October 6, 2026.
Other flights from Quito
Browse through other flights departing from Quito. Flights are based on user searches made on Cheapflights and were last updated on October 6, 2026.
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Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 6, 2026.
Top 4 airlines flying from Quito to Santiago
Discover the top 4 airlines that operate flights from Quito to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$198 | Average$396 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$221 | Average$579 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$232 | Average$560 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$275 | Average$554 | FlexibilityNo cancel fee | On-time70% |