How long is the flight from South Carolina to Panama City?

A quick flight from South Carolina to Panama City can take about 7h 55m. United Airlines provides one of the quickest options available for as low as $436. There are 1700 mi between South Carolina and Panama City. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the most popular routes from South Carolina to Panama City?

The most popular route from South Carolina to Panama City is Charlotte Douglas - Panama City Tocumen Intl. You may also consider Columbia Metropolitan - Panama City Tocumen Intl or Charleston - Panama City Tocumen Intl.

What are the most popular airlines that fly from South Carolina to Panama City?

Delta, American Airlines and United Airlines are the most popular airlines when flying from South Carolina to Panama City.

What is the cheapest time of day to fly from SC to PTY?

When flying from South Carolina to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly into for flights to Panama City from South Carolina?

Located just 11.4 mi from the city center, Panama City Tocumen Intl (PTY) is the airport most travelers will use when flying to Panama City from South Carolina.

Can I find deals for flights from South Carolina to Panama City that include hotel bookings?

Yes. In addition to deals on South Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Carolina to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Panama City.

Can I find deals for business class flights from South Carolina to Panama City?

Yes. Cheapflights offers flight deals from South Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$189+ Flights from South Carolina to Panama City

Q: How much does it cost to fly round-trip from South Carolina to Panama City?

Airfare is below average for this route at the moment. South Carolina to Panama City flights typically cost between $444 and $608 in January. The cheapest round-trip price found within the last 3 days was $370 on United Airlines (Jan 27-Feb 3).

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Cheap flight deals from South Carolina to Panama City

Cheapest flights from South Carolina to Panama City
Explore the most affordable flight options available from South Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Wed 12/316:07 amCLT - PTY

1 stop13h 31mUnited Airlines

Thu 1/111:55 pmPTY - CLT

1 stop9h 19mUnited Airlines

Deal found 12/28

$688

Wed 12/316:21 pmCAE - PTY

2 stops21h 33mAmerican Airlines

Fri 1/94:50 pmPTY - CAE

2 stops19h 38mAmerican Airlines

Deal found 12/28

$710

Tue 12/3011:15 amCLT - PTY

1 stop8h 47mUnited Airlines

Tue 1/64:41 pmPTY - CLT

1 stop29h 18mUnited Airlines

Deal found 12/29

$740

Wed 12/316:45 amGSP - PTY

1 stop12h 53mUnited Airlines

Fri 1/28:55 amPTY - GSP

1 stop8h 08mUnited Airlines

Deal found 12/28

$747

Mon 12/295:07 amCAE - PTY

2 stops10h 47mAmerican Airlines

Tue 12/304:55 pmPTY - CAE

2 stops21h 15mAmerican Airlines

Deal found 12/28

$760

Wed 12/316:20 amCLT - PTY

1 stop9h 34mAmerican Airlines

Thu 1/14:55 pmPTY - CLT

2 stops13h 38mAmerican Airlines

Deal found 12/28

$792

Mon 12/295:45 amGSP - PTY

1 stop14h 15mDelta

Fri 1/28:00 amPTY - GSP

1 stop7h 45mDelta

Deal found 12/28

$856

Tue 12/308:35 pmCLT - PTY

1 stop17h 18mAmerican Airlines

Tue 1/64:31 pmPTY - CLT

1 stop16h 48mAmerican Airlines

Deal found 12/29

$925

Wed 12/316:20 pmGSP - PTY

2 stops19h 33mGOL

Fri 1/22:53 pmPTY - GSP

2 stops19h 14mGOL

Deal found 12/28

$1,071

Mon 12/298:07 pmGSP - PTY

2 stops19h 47mAmerican Airlines

Fri 1/22:53 pmPTY - GSP

2 stops19h 14mAmerican Airlines

Deal found 12/28

$1,083

Wed 12/317:44 pmCLT - PTY

2 stops14h 46mMultiple Airlines

Thu 1/13:50 pmPTY - CLT

2 stops18h 13mMultiple Airlines

Deal found 12/28

$1,106

Tue 12/306:01 pmSAV - PTY

2 stops19h 52mAmerican Airlines

Sat 1/32:53 pmPTY - SAV

2 stops17h 45mAmerican Airlines

Deal found 12/29

$1,404

Best flights from South Carolina to Panama City
Discover carefully curated flight deals from South Carolina to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 30, 2025.

Tue 1/276:30 amCHS - PTY

1 stop8h 15mUnited Airlines

Tue 2/38:55 amPTY - CHS

1 stop13h 02mUnited Airlines

Deal found 12/28

$370

Tue 1/275:34 pmCHS - PTY

2 stops19h 53mAmerican Airlines

Tue 2/32:27 pmPTY - CHS

2 stops23h 58mAmerican Airlines

Deal found 12/29

$374

Tue 2/177:00 amCLT - PTY

2 stops18h 00mMultiple Airlines

Wed 2/255:50 pmPTY - CLT

2 stops18h 30mMultiple Airlines

Deal found 12/29

$418

Wed 5/66:00 amMYR - PTY

1 stop7h 55mDelta

Tue 5/122:20 pmPTY - MYR

1 stop8h 18mDelta

Deal found 12/27

$436

Wed 2/115:24 pmCHS - PTY

2 stops21h 51mAmerican Airlines

Wed 2/182:40 pmPTY - CHS

2 stops20h 36mAmerican Airlines

Deal found 12/28

$374

Tue 5/267:00 amGSP - PTY

1 stop12h 37mUnited Airlines

Tue 6/210:00 amPTY - GSP

1 stop10h 46mUnited Airlines

Deal found 12/28

$392

Sat 3/147:02 pmCHS - PTY

2 stops20h 18mAmerican Airlines

Tue 3/173:10 pmPTY - CHS

2 stops18h 15mAmerican Airlines

Deal found 12/28

$394

Wed 1/216:49 amGSP - PTY

1 stop10h 18mUnited Airlines

Wed 2/49:55 amPTY - GSP

1 stop12h 02mUnited Airlines

Deal found 12/28

$398

Thu 2/127:00 amCLT - PTY

2 stops18h 00mMultiple Airlines

Tue 2/175:50 pmPTY - CLT

2 stops18h 30mMultiple Airlines

Deal found 12/29

$439

Mon 3/25:25 amCLT - PTY

1 stop8h 25mDelta

Tue 3/33:15 pmPTY - CLT

1 stop17h 25mDelta

Deal found 12/28

$468

Sun 2/15:41 pmCHS - PTY

2 stops19h 46mAmerican Airlines

Fri 2/64:50 pmPTY - CHS

2 stops18h 51mAmerican Airlines

Deal found 12/28

$394

Mon 2/27:00 amCLT - PTY

2 stops17h 40mMultiple Airlines

Sat 2/75:50 pmPTY - CLT

2 stops18h 32mMultiple Airlines

Deal found 12/29

$448

Tue 5/268:08 pmGSP - PTY

1 stop17h 02mAmerican Airlines

Tue 6/21:10 pmPTY - GSP

2 stops20h 39mAmerican Airlines

Deal found 12/28

$396

Tue 3/37:00 amCLT - PTY

2 stops18h 00mMultiple Airlines

Sun 3/152:55 amPTY - CLT

2 stops16h 28mMultiple Airlines

Deal found 12/30

$452

Wed 3/46:33 amCLT - PTY

1 stop13h 05mUnited Airlines

Mon 3/911:35 amPTY - CLT

1 stop9h 24mUnited Airlines

Deal found 12/28

$468

Wed 1/285:40 pmGSP - PTY

2 stops19h 47mAmerican Airlines

Thu 2/54:50 pmPTY - GSP

1 stop7h 07mAmerican Airlines

Deal found 12/29

$396

Thu 2/2611:23 amCLT - PTY

1 stop8h 39mUnited Airlines

Tue 3/34:41 pmPTY - CLT

1 stop18h 06mUnited Airlines

Deal found 12/28

$468

Sat 2/77:00 amCLT - PTY

2 stops18h 00mMultiple Airlines

Fri 2/202:55 amPTY - CLT

2 stops15h 07mMultiple Airlines

Deal found 12/28

$472

Thu 2/268:25 pmCHS - PTY

2 stops17h 15mAmerican Airlines

Sun 3/14:05 pmPTY - CHS

2 stops20h 37mAmerican Airlines

Deal found 12/29

$399

Sat 5/25:30 amCAE - PTY

1 stop8h 25mDelta

Thu 5/212:20 pmPTY - CAE

1 stop8h 35mDelta

Deal found 12/28

$598

Wed 3/2511:28 amCLT - PTY

1 stop8h 10mUnited Airlines

Mon 4/63:30 pmPTY - CLT

1 stop18h 21mUnited Airlines

Deal found 12/29

$468

Wed 1/217:42 pmGSP - PTY

2 stops19h 56mAmerican Airlines

Wed 2/42:27 pmPTY - GSP

2 stops20h 57mAmerican Airlines

Deal found 12/29

$402

Wed 2/256:33 amCLT - PTY

1 stop8h 12mUnited Airlines

Thu 3/510:00 amPTY - CLT

1 stop11h 15mUnited Airlines

Deal found 12/28

$468

Sat 5/26:00 amGSP - PTY

1 stop7h 36mAmerican Airlines

Fri 5/81:49 pmPTY - GSP

2 stops21h 25mAmerican Airlines

Deal found 12/29

$414

Wed 2/2511:23 amCLT - PTY

1 stop8h 39mUnited Airlines

Tue 3/34:41 pmPTY - CLT

1 stop18h 06mUnited Airlines

Deal found 12/28

$468

Mon 5/46:17 pmGSP - PTY

2 stops19h 19mAmerican Airlines

Mon 5/111:49 pmPTY - GSP

2 stops21h 16mAmerican Airlines

Deal found 12/29

$414

Wed 2/116:50 amAGS - PTY

1 stop7h 05mDelta

Wed 2/183:15 pmPTY - AGS

1 stop6h 42mDelta

Deal found 12/28

$762

Wed 2/411:46 amSAV - PTY

1 stop7h 52mUnited Airlines

Wed 2/118:55 amPTY - SAV

1 stop12h 50mUnited Airlines

Deal found 12/28

$476

Mon 5/117:38 pmGSP - PTY

2 stops17h 58mAmerican Airlines

Sun 5/171:49 pmPTY - GSP

2 stops21h 16mAmerican Airlines

Deal found 12/28

$419

Thu 2/125:35 amAGS - PTY

1 stop8h 15mDelta

Tue 2/173:15 pmPTY - AGS

1 stop6h 42mDelta

Deal found 12/29

$762

Last-minute flights from South Carolina to Panama City
Discover last-minute flight deals from South Carolina to Panama City. Data last updated December 30, 2025 and is based on user searches.

Mon 1/127:00 pmGSP - PTY

2 stops18h 27mAmerican Airlines

Mon 3/22:40 pmPTY - GSP

2 stops21h 34mAmerican Airlines

Deal found 12/28

$420

Mon 1/126:30 amCHS - PTY

1 stop8h 15mUnited Airlines

Thu 1/1511:35 amPTY - CHS

1 stop28h 42mUnited Airlines

Deal found 12/28

$443

Mon 1/126:00 amCHS - PTY

1 stop9h 38mAmerican Airlines

Thu 1/154:50 pmPTY - CHS

2 stops16h 58mAmerican Airlines

Deal found 12/28

$458

Wed 1/145:13 pmCHS - PTY

1 stop26h 25mUnited Airlines

Wed 1/214:41 pmPTY - CHS

1 stop23h 36mUnited Airlines

Deal found 12/28

$452

Fri 1/1610:55 amCHS - PTY

1 stop9h 07mUnited Airlines

Sun 2/14:41 pmPTY - CHS

1 stop29h 16mUnited Airlines

Deal found 12/28

$450

Fri 1/165:41 pmCHS - PTY

2 stops19h 46mAmerican Airlines

Sun 2/14:50 pmPTY - CHS

1 stop15h 57mAmerican Airlines

Deal found 12/28

$451

Wed 1/216:49 amGSP - PTY

1 stop10h 18mUnited Airlines

Wed 2/49:55 amPTY - GSP

1 stop12h 02mUnited Airlines

Deal found 12/28

$398

Wed 1/216:23 pmGSP - PTY

2 stops21h 15mAmerican Airlines

Wed 2/42:27 pmPTY - GSP

2 stops21h 40mAmerican Airlines

Deal found 12/28

$402

Fri 1/237:00 amCLT - PTY

2 stops17h 40mMultiple Airlines

Sun 1/252:55 pmPTY - CLT

2 stops21h 27mMultiple Airlines

Deal found 12/29

$428

Tue 1/276:30 amCHS - PTY

1 stop10h 37mUnited Airlines

Tue 2/38:55 amPTY - CHS

1 stop13h 02mUnited Airlines

Deal found 12/29

$370

Tue 1/276:00 amCHS - PTY

1 stop7h 27mAmerican Airlines

Tue 2/32:27 pmPTY - CHS

2 stops21h 07mAmerican Airlines

Deal found 12/28

$374

Wed 1/287:42 pmGSP - PTY

2 stops19h 56mAmerican Airlines

Thu 2/54:50 pmPTY - GSP

2 stops17h 40mAmerican Airlines

Deal found 12/29

$396

One-way flights from South Carolina to Panama City
Search for one-way flight options from South Carolina to Panama City. Find affordable one-way fares based on user searches. Data last updated December 30, 2025.

Fri 1/237:00 amCLT - PTY

2 stops17h 40mMultiple Airlines

Deal found 12/29

$189

Thu 2/56:23 amMYR - PTY

2 stops9h 15mAmerican Airlines

Deal found 12/28

$205

Tue 1/610:34 amCLT - PTY

3 stops23h 56mMultiple Airlines

Deal found 12/28

$225

Fri 1/237:55 amCLT - PTY

1 stop7h 43mAmerican Airlines

Deal found 12/29

$241

Fri 4/34:45 pmCLT - PTY

1 stop24h 27mUnited Airlines

Deal found 12/30

$257

Tue 1/65:25 amCLT - PTY

1 stop8h 30mDelta

Deal found 12/28

$271

Tue 1/610:17 pmCLT - PTY

2 stops15h 10mAmerican Airlines

Deal found 12/28

$277

Thu 1/111:40 amSAV - PTY

1 stop7h 58mUnited Airlines

Deal found 12/28

$295

Thu 2/56:00 amMYR - PTY

1 stop7h 55mDelta

Deal found 12/29

$327

Thu 1/11:23 pmSAV - PTY

3 stops29h 08mMultiple Airlines

Deal found 12/28

$594

Fri 4/311:08 pmCLT - PTY

2 stops16h 53mAmerican Airlines

Deal found 12/30

$1,256

Find flight deals from South Carolina to Panama City

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Round-trip from	$370 (United Airlines)
One-way from	$189 (Avianca Connect)

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From South Carolina to Panama City Tocumen Intl

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Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 1/27

6:30 am-2:45 pm

1 stop8h 15m

Panama City Tocumen Intl

Tue 2/3

8:55 am-9:57 pm

1 stop13h 02m

$370

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 1/27

5:34 pm-1:27 pm

2 stops19h 53m

Panama City Tocumen Intl

Tue 2/3

2:27 pm-2:25 pm

2 stops23h 58m

$374

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 2/11

5:24 pm-3:15 pm

2 stops21h 51m

Panama City Tocumen Intl

Wed 2/18

2:40 pm-11:16 am

2 stops20h 36m

$374

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 5/26

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Tue 6/2

10:00 am-9:46 pm

1 stop10h 46m

$392

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

7:02 pm-2:20 pm

2 stops20h 18m

Panama City Tocumen Intl

Tue 3/17

3:10 pm-10:25 am

2 stops18h 15m

$394

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sun 2/1

5:41 pm-1:27 pm

2 stops19h 46m

Panama City Tocumen Intl

Fri 2/6

4:50 pm-11:41 am

2 stops18h 51m

$394

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 5/26

8:08 pm-12:10 pm

1 stop17h 02m

Panama City Tocumen Intl

Tue 6/2

1:10 pm-10:49 am

2 stops20h 39m

$396

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 1/28

5:40 pm-1:27 pm

2 stops19h 47m

Panama City Tocumen Intl

Thu 2/5

4:50 pm-11:57 pm

1 stop7h 07m

$396

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Wed 1/21

6:49 am-5:07 pm

1 stop10h 18m

Panama City Tocumen Intl

Wed 2/4

9:55 am-9:57 pm

1 stop12h 02m

$398

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 2/26

8:25 pm-1:40 pm

2 stops17h 15m

Panama City Tocumen Intl

Sun 3/1

4:05 pm-12:42 pm

2 stops20h 37m

$399

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Showing 1-10 of 42 results

...

Best time to book a flight from South Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from South Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Panama City

What is the cheapest month to book a flight from South Carolina to Panama City?

Currently, July is the cheapest month in which you can book a flight from South Carolina to Panama City (average of $230). Flying from South Carolina to Panama City in May is currently the most expensive (average of $419). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from South Carolina to Panama City?

Related info for your journey

What airport do you fly into for flights to Panama City from South Carolina?
Located just 11.4 mi from the city center, Panama City Tocumen Intl (PTY) is the airport most travelers will use when flying to Panama City from South Carolina.
How long is the flight from South Carolina to Panama City?
A quick flight from South Carolina to Panama City can take about 7h 55m. United Airlines provides one of the quickest options available for as low as $436. There are 1700 mi between South Carolina and Panama City. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the most popular routes from South Carolina to Panama City?
The most popular route from South Carolina to Panama City is Charlotte Douglas - Panama City Tocumen Intl. You may also consider Columbia Metropolitan - Panama City Tocumen Intl or Charleston - Panama City Tocumen Intl.
Can I find deals for flights from South Carolina to Panama City that include hotel bookings?
Yes. In addition to deals on South Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Panama City.
Can I find deals for business class flights from South Carolina to Panama City?
Yes. Cheapflights offers flight deals from South Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from South Carolina to Panama City?
Currently, July is the cheapest month in which you can book a flight from South Carolina to Panama City (average of $230). Flying from South Carolina to Panama City in May is currently the most expensive (average of $419). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from South Carolina to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$349	Average$527	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$363	Average$570	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$369	Average$450	FlexibilityNo cancel fee	On-time69%

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$189+ Cheap flights from South Carolina to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from South Carolina to Panama City

Cheapest flights from South Carolina to Panama CityExplore the most affordable flight options available from South Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Explore the most affordable flight options available from South Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Find flight deals from South Carolina to Panama City

Keep the following information in mind while searching for South Carolina to Panama City flight deals. Data was last updated December 30, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Panama City that are best for you.

Best time to book a flight from South Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from South Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Panama City

What is the cheapest month to book a flight from South Carolina to Panama City?

How much does it cost to fly round-trip from South Carolina to Panama City?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Panama City from South Carolina?

How long is the flight from South Carolina to Panama City?

What are the most popular routes from South Carolina to Panama City?

Can I find deals for flights from South Carolina to Panama City that include hotel bookings?

How can I find direct flights from South Carolina to Panama City?

Can I find deals for business class flights from South Carolina to Panama City?

What is the cheapest month to book a flight from South Carolina to Panama City?

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Alternative routes for South Carolina to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from South Carolina to Panama City

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Cheapest flights from South Carolina to Panama City
Explore the most affordable flight options available from South Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.