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Panama City

$249+ Cheap flights from Mississippi to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/2. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — PTY
Jun 5 — Jun 121
Fri 6/5
Fri 6/12
1 adult, Economy
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Cheap flight deals from Mississippi to Panama City

Cheapest flights from Mississippi to Panama City
Explore the most affordable flight options available from Mississippi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.

This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:00 am
MEM
-
PTY
1 stop11h 38m
United Airlines
Wed 1/278:55 am
PTY
-
MEM
1 stop13h 43m
United Airlines
Deal found 5/3$467
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:22 pm
MEM
-
PTY
2 stops24h 40m
United Airlines
Mon 1/254:41 pm
PTY
-
MEM
2 stops23h 07m
United Airlines
Deal found 5/3$471
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:55 pm
MEM
-
PTY
1 stop19h 01m
Delta
Wed 1/273:20 pm
PTY
-
MEM
1 stop7h 22m
Delta
Deal found 5/3$474
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:00 am
MEM
-
PTY
1 stop22h 04m
United Airlines
Thu 7/239:45 am
PTY
-
MEM
1 stop13h 45m
United Airlines
Deal found 5/1$476
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:55 pm
MEM
-
PTY
1 stop19h 01m
Delta
Thu 1/283:20 pm
PTY
-
MEM
1 stop20h 33m
Delta
Deal found 5/3$481
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am
MEM
-
PTY
1 stop13h 02m
United Airlines
Wed 1/278:55 am
PTY
-
MEM
1 stop8h 18m
United Airlines
Deal found 5/3$486
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:00 am
MEM
-
PTY
1 stop6h 45m
United Airlines
Wed 1/2711:35 am
PTY
-
MEM
1 stop11h 03m
United Airlines
Deal found 5/3$499
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:50 am
MEM
-
PTY
1 stop7h 24m
United Airlines
Wed 8/193:30 pm
PTY
-
MEM
1 stop17h 35m
United Airlines
Deal found 5/5$501
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:00 am
MEM
-
PTY
1 stop6h 45m
United Airlines
Mon 1/254:41 pm
PTY
-
MEM
2 stops23h 07m
United Airlines
Deal found 5/3$503
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:22 pm
MEM
-
PTY
2 stops24h 40m
United Airlines
Tue 1/268:55 am
PTY
-
MEM
1 stop8h 18m
United Airlines
Deal found 5/3$505
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:55 pm
MEM
-
PTY
1 stop19h 01m
Delta
Fri 1/293:20 pm
PTY
-
MEM
1 stop8h 28m
Delta
Deal found 5/3$508
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:00 am
JAN
-
PTY
1 stop9h 37m
United Airlines
Thu 8/133:30 pm
PTY
-
JAN
1 stop27h 58m
United Airlines
Deal found 5/3$534

Find flight deals from Mississippi to Panama City

Keep the following information in mind while searching for Mississippi to Panama City flight deals. Data was last updated May 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$467
(United Airlines)

One-way from

$249
(United Airlines)
Provider with most accurate pricing for Jackson-Evers Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Panama City Tocumen Intl flights.
Search Deals
From Mississippi to Panama City Tocumen Intl
Search Deals
One-way flight from Mississippi to Panama City Tocumen Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Mississippi to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Sat 8/15

6:50 am-2:14 pm

1 stop7h 24m

Panama City Tocumen Intl

Wed 8/19

3:30 pm-9:05 am

1 stop17h 35m

$501

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Sat 8/1

6:20 am-1:00 pm

1 stop6h 40m

Panama City Tocumen Intl

Thu 8/6

2:20 pm-11:24 pm

1 stop9h 04m

$501

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Sat 8/1

7:25 am-4:04 am

2 stops20h 39m

Panama City Tocumen Intl

Thu 8/6

3:30 pm-9:05 am

1 stop17h 35m

$505

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Thu 7/16

6:00 am-4:04 am

1 stop22h 04m

Panama City Tocumen Intl

Thu 7/23

10:55 pm-11:21 pm

2 stops24h 26m

$512

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Tue 8/11

9:00 am-6:37 pm

1 stop9h 37m

Panama City Tocumen Intl

Thu 8/13

3:30 pm-7:28 pm

1 stop27h 58m

$534

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Sat 10/17

7:00 am-6:37 pm

1 stop11h 37m

Panama City Tocumen Intl

Tue 10/20

10:00 am-6:17 pm

1 stop8h 17m

$557

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Tue 6/2

5:10 pm-6:37 pm

1 stop25h 27m

Panama City Tocumen Intl

Tue 6/9

3:30 pm-4:15 pm

1 stop24h 45m

$583

Baton RougePanama City

BTR - PTY

BTRPTY

Baton Rouge Ryan

Sun 8/30

6:14 pm-2:14 pm

1 stop20h 00m

Panama City Tocumen Intl

Tue 9/1

3:30 pm-8:43 am

1 stop17h 13m

$630

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Tue 5/19

11:20 am-6:37 pm

1 stop7h 17m

Panama City Tocumen Intl

Fri 5/22

10:55 pm-8:25 pm

2 stops21h 30m

$641

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Thu 6/4

4:21 pm-12:13 pm

2 stops19h 52m

Panama City Tocumen Intl

Thu 6/11

1:15 pm-10:26 am

2 stops21h 11m

$671

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/2

Showing 1-10 of 44 resultsSorted by cheapest first
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Best time to book a flight from Mississippi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Panama City
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Mississippi?

    Most people fly into Panama City Tocumen Intl (PTY) if they book a flight to Panama City from Mississippi. Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • How long is the flight from Mississippi to Panama City?

    There are many flights that can get you from Mississippi to Panama City in 6h 40m. Fly via United Airlines, Delta, or American Airlines to get the fastest option. Mississippi and Panama City are separated by a distance of 1914 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Mississippi to Panama City?

    While some choose either Baton Rouge Ryan - Panama City Tocumen Intl or Jackson-Evers Intl - Panama City Tocumen Intl, Memphis - Panama City Tocumen Intl is the most popular route from Mississippi to Panama City.

  • Can I find deals for flights from Mississippi to Panama City that include hotel bookings?

    Yes. In addition to deals on Mississippi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Panama City.

  • Can I find deals for business class flights from Mississippi to Panama City?

    Yes. Cheapflights offers flight deals from Mississippi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Mississippi to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Mississippi to Panama City

Discover the top airline that operate flights from Mississippi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$445Average$627FlexibilityNo cancel feeOn-time69%

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