How long is the flight from Mississippi to Panama City?

There are many flights that can get you from Mississippi to Panama City in 11h 37m. Fly via United Airlines, American Airlines, or Copa Airlines to get the fastest option. Mississippi and Panama City are separated by a distance of 1600 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the most popular routes from Mississippi to Panama City?

While some choose either Memphis - Panama City Tocumen Intl or Mobile - Panama City Tocumen Intl, Jackson-Evers Intl - Panama City Tocumen Intl is the most popular route from Mississippi to Panama City.

What is the cheapest time of day to fly from MS to PTY?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Panama City as you normally would.

What airport do you fly into for flights to Panama City from Mississippi?

Most people fly into Panama City Tocumen Intl (PTY) if they book a flight to Panama City from Mississippi. Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

Can I find deals for flights from Mississippi to Panama City that include hotel bookings?

Yes. In addition to deals on Mississippi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mississippi to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Panama City.

Can I find deals for business class flights from Mississippi to Panama City?

Yes. Cheapflights offers flight deals from Mississippi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$477+ Cheap Flights from Mississippi to Panama City

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Cheap flight deals from Mississippi to Panama City

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Cheapest flights from Mississippi to Panama City
Explore the most affordable flight options available from Mississippi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.

Mon 12/711:58 am -

1 stop6h 40m

Mon 12/148:55 am -

1 stop8h 39m

Deal found 11/7

$775

Mon 12/75:53 pm -

2 stops19h 20m

Mon 12/143:13 pm -

2 stops21h 26m

Deal found 11/7

$883

Thu 12/249:00 am -

1 stop9h 38m

Thu 12/318:55 am -

1 stop14h 04m

Deal found 11/8

$1,279

Best flights from Mississippi to Panama City
Discover carefully curated flight deals from Mississippi to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.

Mon 4/267:00 am -

1 stop11h 37m

Wed 4/287:55 am -

1 stop7h 58m

Deal found 11/4

$681

Sat 1/164:58 pm -

2 stops21h 57m

Mon 1/254:55 pm -

2 stops19h 44m

Deal found 11/7

$792

Sat 5/17:00 am -

1 stop11h 37m

Wed 5/510:00 am -

1 stop9h 42m

Deal found 11/7

$734

Sat 1/162:00 pm -

1 stop23h 45m

Mon 1/258:55 am -

1 stop27h 31m

Deal found 11/7

$814

Thu 12/249:00 am -

1 stop9h 38m

Thu 12/318:55 am -

1 stop14h 04m

Deal found 11/8

$1,279

Sat 1/162:00 pm -

2 stops16h 49m

Mon 1/258:55 am -

1 stop8h 38m

Deal found 11/7

$3,389

Mon 12/711:58 am -

1 stop6h 40m

Mon 12/149:25 am -

2 stops13h 16m

Deal found 11/7

$5,097

Find flight deals from Mississippi to Panama City

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Round-trip from	$681 (United Airlines)
One-way from	$477 (United Airlines)

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GulfportPanama City

GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl

GPTPTY

Gulfport Biloxi Regional

Mon 12/7

7:00 am-7:38 pm

1 stop11h 38m

Panama City Tocumen Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$477

JacksonPanama City

JAN Jackson-Evers Intl - PTY Panama City Tocumen Intl

JANPTY

Jackson-Evers Intl

Mon 4/26

7:00 am-6:37 pm

1 stop11h 37m

Panama City Tocumen Intl

Wed 4/28

7:55 am-3:53 pm

1 stop7h 58m

$681

GulfportPanama City

GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl

GPTPTY

Gulfport Biloxi Regional

Sat 5/1

7:00 am-6:37 pm

1 stop11h 37m

Panama City Tocumen Intl

Wed 5/5

10:00 am-7:42 pm

1 stop9h 42m

$734

JacksonPanama City

JAN Jackson-Evers Intl - PTY Panama City Tocumen Intl

JANPTY

Jackson-Evers Intl

Sat 1/16

4:58 pm-3:55 pm

2 stops21h 57m

Panama City Tocumen Intl

Mon 1/25

4:55 pm-11:39 am

2 stops19h 44m

$792

JacksonPanama City

JAN Jackson-Evers Intl - PTY Panama City Tocumen Intl

JANPTY

Jackson-Evers Intl

Sat 1/16

2:00 pm-2:45 pm

1 stop23h 45m

Panama City Tocumen Intl

Mon 1/25

8:55 am-11:26 am

1 stop27h 31m

$814

JacksonPanama City

JAN Jackson-Evers Intl - PTY Panama City Tocumen Intl

JANPTY

Jackson-Evers Intl

Thu 12/24

9:00 am-7:38 pm

1 stop9h 38m

Panama City Tocumen Intl

Thu 12/31

8:55 am-9:59 pm

1 stop14h 04m

$1,279

JacksonPanama City

JAN Jackson-Evers Intl - PTY Panama City Tocumen Intl

JANPTY

Jackson-Evers Intl

Sat 1/16

2:00 pm-7:49 am

2 stops16h 49m

Panama City Tocumen Intl

Mon 1/25

8:55 am-4:33 pm

1 stop8h 38m

$3,389

JacksonPanama City

JAN Jackson-Evers Intl - PTY Panama City Tocumen Intl

JANPTY

Jackson-Evers Intl

Mon 12/7

11:58 am-7:38 pm

1 stop6h 40m

Panama City Tocumen Intl

Mon 12/14

9:25 am-9:41 pm

2 stops13h 16m

$5,097

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Sorted by cheapest first

Best time to book a flight from Mississippi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mississippi with our price prediction graph.

JAN-PTY

GPT-PTY

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

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Everything you need to know about your flight from Mississippi to Panama City

USMS-PTY

JAN-PTY

GPT-PTY

No data available for this route at this time. Please check back soon.

Related info for your journey

What airport do you fly into for flights to Panama City from Mississippi?
Most people fly into Panama City Tocumen Intl (PTY) if they book a flight to Panama City from Mississippi. Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.
How long is the flight from Mississippi to Panama City?
There are many flights that can get you from Mississippi to Panama City in 11h 37m. Fly via United Airlines, American Airlines, or Copa Airlines to get the fastest option. Mississippi and Panama City are separated by a distance of 1600 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the most popular routes from Mississippi to Panama City?
While some choose either Memphis - Panama City Tocumen Intl or Mobile - Panama City Tocumen Intl, Jackson-Evers Intl - Panama City Tocumen Intl is the most popular route from Mississippi to Panama City.
Can I find deals for flights from Mississippi to Panama City that include hotel bookings?
Yes. In addition to deals on Mississippi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mississippi to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Panama City.
Can I find deals for business class flights from Mississippi to Panama City?
Yes. Cheapflights offers flight deals from Mississippi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top 2 airlines flying from Mississippi to Panama City

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$524	Average$786	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$786	Average$1,058	FlexibilityNo cancel fee	On-timeN/A

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$477+ Cheap flights from Mississippi to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Mississippi to Panama City

Cheapest flights from Mississippi to Panama CityExplore the most affordable flight options available from Mississippi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.

Explore the most affordable flight options available from Mississippi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.

Best flights from Mississippi to Panama CityDiscover carefully curated flight deals from Mississippi to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.

Discover carefully curated flight deals from Mississippi to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.

Last-minute flights from Mississippi to Panama CityDiscover last-minute flight deals from Mississippi to Panama City. Data last updated November 9, 2026 and is based on user searches.

Discover last-minute flight deals from Mississippi to Panama City. Data last updated November 9, 2026 and is based on user searches.

One-way flights from Mississippi to Panama CitySearch for one-way flight options from Mississippi to Panama City. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.

Search for one-way flight options from Mississippi to Panama City. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.

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Related info for your journey

What airport do you fly into for flights to Panama City from Mississippi?

How long is the flight from Mississippi to Panama City?

What are the most popular routes from Mississippi to Panama City?

Can I find deals for flights from Mississippi to Panama City that include hotel bookings?

How can I find direct flights from Mississippi to Panama City?

Can I find deals for business class flights from Mississippi to Panama City?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to Panama City

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Mississippi and Panama City flights

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Cheapest flights from Mississippi to Panama City
Explore the most affordable flight options available from Mississippi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.

Best flights from Mississippi to Panama City
Discover carefully curated flight deals from Mississippi to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.

Last-minute flights from Mississippi to Panama City
Discover last-minute flight deals from Mississippi to Panama City. Data last updated November 9, 2026 and is based on user searches.

One-way flights from Mississippi to Panama City
Search for one-way flight options from Mississippi to Panama City. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.