$271+ Cheap flights from Mississippi to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — PTY
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Mississippi to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
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Cheapest flights from Mississippi to PanamaExplore the most affordable flight options available from Mississippi to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Mississippi to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:00 am -
1 stop6h 45m
Wed 11/48:55 am -
1 stop8h 13m
Deal found 9/5![United Airlines logo]()
$601
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:02 pm -
2 stops19h 00m
Wed 11/43:13 pm -
2 stops20h 58m
Deal found 9/5![American Airlines logo]()
$605
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
1 stop13h 02m
Wed 11/48:55 am -
1 stop8h 23m
Deal found 9/7![United Airlines logo]()
$607
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:31 am -
1 stop7h 07m
Tue 11/38:55 am -
1 stop12h 11m
Deal found 9/10![United Airlines logo]()
$632
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am -
1 stop7h 14m
Tue 10/273:41 pm -
1 stop19h 34m
Deal found 9/5![United Airlines logo]()
$637
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:30 am -
1 stop7h 15m
Fri 10/303:41 pm -
1 stop17h 21m
Deal found 9/9![United Airlines logo]()
$641
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:55 pm -
1 stop20h 50m
Sun 11/88:55 am -
1 stop8h 13m
Deal found 9/7![United Airlines logo]()
$648
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop13h 31m
Sat 10/103:30 pm -
1 stop17h 37m
Deal found 9/5![United Airlines logo]()
$657
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:35 am -
1 stop9h 02m
Wed 10/1410:00 am -
1 stop9h 31m
Deal found 9/9![United Airlines logo]()
$657
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/316:48 am -
1 stop9h 24m
Mon 1/114:41 pm -
2 stops27h 29m
Deal found 9/9![United Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:26 pm -
2 stops19h 36m
Sat 10/312:02 pm -
2 stops27h 55m
Deal found 9/8![American Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:17 pm -
2 stops18h 45m
Thu 10/292:02 pm -
2 stops27h 42m
Deal found 9/7![American Airlines logo]()
$664
Best flights from Mississippi to PanamaDiscover carefully curated flight deals from Mississippi to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Mississippi to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:00 am -
1 stop6h 45m
Wed 11/48:55 am -
1 stop8h 13m
Deal found 9/5![United Airlines logo]()
$601
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:02 pm -
2 stops19h 00m
Wed 11/43:13 pm -
2 stops20h 58m
Deal found 9/5![American Airlines logo]()
$605
This Faresmojo deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:00 am -
1 stop7h 03m
Sun 1/103:20 pm -
1 stop7h 41m
Deal found 9/7![JetBlue logo]()
$767
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/3112:07 pm -
1 stop8h 36m
Mon 1/113:20 pm -
1 stop7h 32m
Deal found 9/9![Delta logo]()
$793
This BusinessClass deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:36 pm -
2 stops17h 37m
Sun 1/104:55 pm -
2 stops29h 15m
Deal found 9/7![GOL logo]()
$893
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:46 pm -
2 stops25h 33m
Sun 11/86:42 pm -
1 stop15h 09m
Deal found 9/7![Multiple Airlines logo]()
$983
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
1 stop13h 02m
Wed 11/48:55 am -
1 stop8h 23m
Deal found 9/7![United Airlines logo]()
$607
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:26 pm -
2 stops19h 36m
Sat 10/312:02 pm -
2 stops27h 55m
Deal found 9/8![American Airlines logo]()
$661
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:14 pm -
2 stops24h 48m
Tue 11/38:55 am -
1 stop10h 10m
Deal found 9/6![United Airlines logo]()
$611
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:17 pm -
2 stops18h 45m
Thu 10/292:02 pm -
2 stops27h 42m
Deal found 9/7![American Airlines logo]()
$664
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:00 am -
1 stop9h 37m
Wed 10/289:30 am -
2 stops25h 20m
Deal found 9/5![United Airlines logo]()
$636
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:29 pm -
2 stops18h 33m
Wed 10/282:02 pm -
2 stops28h 02m
Deal found 9/6![American Airlines logo]()
$666
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am -
1 stop7h 14m
Tue 10/273:41 pm -
1 stop19h 34m
Deal found 9/5![United Airlines logo]()
$637
This BusinessClass deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:55 pm -
1 stop23h 17m
Fri 1/88:55 am -
1 stop8h 07m
Deal found 9/6![Copa Airlines logo]()
$1,788
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
1 stop6h 59m
Fri 11/273:29 pm -
1 stop24h 32m
Deal found 9/7![Delta logo]()
$926
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:30 am -
1 stop7h 15m
Fri 10/303:41 pm -
2 stops23h 03m
Deal found 9/9![United Airlines logo]()
$645
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:42 pm -
2 stops18h 34m
Wed 10/72:02 pm -
2 stops21h 11m
Deal found 9/9![American Airlines logo]()
$723
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:00 am -
1 stop6h 59m
Fri 11/273:29 pm -
1 stop24h 32m
Deal found 9/7![Delta logo]()
$926
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:55 pm -
1 stop20h 50m
Sun 11/88:55 am -
1 stop8h 13m
Deal found 9/8![United Airlines logo]()
$648
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:46 pm -
2 stops25h 45m
Sun 11/19:16 am -
1 stop24h 35m
Deal found 9/9![Multiple Airlines logo]()
$1,073
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:51 pm -
2 stops19h 11m
Sat 10/312:02 pm -
2 stops29h 12m
Deal found 9/8![American Airlines logo]()
$756
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/11:04 pm -
1 stop23h 55m
Fri 11/273:29 pm -
1 stop24h 32m
Deal found 9/7![Delta logo]()
$935
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop13h 31m
Sat 10/103:30 pm -
1 stop17h 37m
Deal found 9/5![United Airlines logo]()
$657
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:00 pm -
1 stop20h 59m
Fri 11/273:29 pm -
1 stop18h 02m
Deal found 9/7![Delta logo]()
$935
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:00 am -
1 stop9h 37m
Fri 10/307:55 am -
1 stop10h 10m
Deal found 9/7![United Airlines logo]()
$657
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:32 am -
1 stop7h 05m
Fri 10/233:30 pm -
1 stop17h 37m
Deal found 9/9![United Airlines logo]()
$657
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
1 stop6h 59m
Fri 11/273:29 pm -
1 stop18h 02m
Deal found 9/7![Delta logo]()
$979
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/316:52 pm -
2 stops17h 59m
Mon 1/114:55 pm -
2 stops19h 40m
Deal found 9/9![American Airlines logo]()
$948
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:35 am -
1 stop9h 02m
Wed 10/1410:00 am -
1 stop9h 31m
Deal found 9/9![United Airlines logo]()
$657
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:45 pm -
1 stop21h 25m
Wed 10/73:05 pm -
2 stops28h 00m
Deal found 9/9![Multiple Airlines logo]()
$1,461
Last-minute flights from Mississippi to PanamaDiscover last-minute flight deals from Mississippi to Panama. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to Panama. Data last updated September 10, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop13h 31m
Sat 10/103:30 pm -
1 stop17h 37m
Deal found 9/5![United Airlines logo]()
$657
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:46 pm -
2 stops20h 16m
Fri 10/302:02 pm -
2 stops21h 43m
Deal found 9/5![American Airlines logo]()
$664
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:35 am -
1 stop9h 02m
Wed 10/1410:00 am -
1 stop9h 31m
Deal found 9/9![United Airlines logo]()
$657
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am -
1 stop7h 14m
Tue 10/273:41 pm -
1 stop19h 34m
Deal found 9/5![United Airlines logo]()
$637
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:17 pm -
2 stops18h 45m
Thu 10/292:02 pm -
2 stops27h 42m
Deal found 9/7![American Airlines logo]()
$664
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:26 pm -
2 stops19h 36m
Sat 10/312:02 pm -
2 stops27h 55m
Deal found 9/8![American Airlines logo]()
$661
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:31 am -
1 stop7h 07m
Tue 11/38:55 am -
1 stop12h 11m
Deal found 9/10![United Airlines logo]()
$632
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
1 stop13h 02m
Wed 11/48:55 am -
1 stop8h 23m
Deal found 9/7![United Airlines logo]()
$607
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:00 am -
1 stop6h 45m
Wed 11/48:55 am -
1 stop8h 13m
Deal found 9/5![United Airlines logo]()
$601
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:02 pm -
2 stops19h 00m
Wed 11/43:13 pm -
2 stops20h 58m
Deal found 9/5![American Airlines logo]()
$605
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:30 am -
1 stop7h 15m
Fri 10/303:41 pm -
1 stop17h 21m
Deal found 9/9![United Airlines logo]()
$641
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:55 pm -
1 stop20h 50m
Sun 11/88:55 am -
1 stop8h 13m
Deal found 9/7![United Airlines logo]()
$648
One-way flights from Mississippi to PanamaSearch for one-way flight options from Mississippi to Panama. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Mississippi to Panama. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:00 am -
2 stops11h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![United Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/309:15 am -
1 stop11h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$296
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:30 am -
1 stop12h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![United Airlines logo]()
$305
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:35 am -
1 stop9h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:03 am -
1 stop6h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Delta logo]()
$404
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:03 am -
1 stop6h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Delta logo]()
$414
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:42 pm -
2 stops18h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:25 am -
1 stop6h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Delta logo]()
$452
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/292:00 pm -
1 stop6h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$641
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3012:50 pm -
2 stops24h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![United Airlines logo]()
$783
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:59 pm -
3 stops41h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$831
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:03 am -
3 stops31h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$1,186
Find flight deals from Mississippi to Panama
Keep the following information in mind while searching for Mississippi to Panama flight deals. Data was last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $601 (United Airlines) |
One-way from | $271 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Mississippi to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MemphisPanama City
MEM Memphis - PTY Panama City Tocumen Intl
MEMPTY
Memphis
Thu 10/29
6:00 am-7:02 pm
1 stop13h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$271
MemphisPanama City
MEM Memphis - PTY Panama City Tocumen Intl
MEMPTY
Memphis
Sun 11/1
6:30 am-7:38 pm
1 stop12h 08m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$305
Baton RougePanama City
BTR Baton Rouge Ryan - PTY Panama City Tocumen Intl
BTRPTY
Baton Rouge Ryan
Fri 9/25
6:03 am-12:58 pm
1 stop6h 55m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$404
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Tue 9/29
5:42 pm-12:26 pm
2 stops18h 44m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$447
Quickest round-trip
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Tue 9/29
6:25 am-12:58 pm
1 stop6h 33m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$452
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Thu 10/29
7:00 am-1:45 pm
1 stop6h 45m
Panama City Tocumen Intl
Wed 11/4
8:55 am-4:08 pm
1 stop8h 13m
$601
GulfportPanama City
GPT Gulfport Biloxi Regional - PTY Panama City Tocumen Intl
GPTPTY
Gulfport Biloxi Regional
Thu 10/29
6:02 pm-1:02 pm
2 stops19h 00m
Panama City Tocumen Intl
Wed 11/4
3:13 pm-11:11 am
2 stops20h 58m
$605
MemphisPanama City
MEM Memphis - PTY Panama City Tocumen Intl
MEMPTY
Memphis
Wed 10/28
6:00 am-7:02 pm
1 stop13h 02m
Panama City Tocumen Intl
Wed 11/4
8:55 am-4:18 pm
1 stop8h 23m
$607
MemphisPanama City
MEM Memphis - PTY Panama City Tocumen Intl
MEMPTY
Memphis
Tue 10/27
6:14 pm-7:02 pm
2 stops24h 48m
Panama City Tocumen Intl
Tue 11/3
8:55 am-6:05 pm
1 stop10h 10m
$611
MemphisPanama City
MEM Memphis - PTY Panama City Tocumen Intl
MEMPTY
Memphis
Wed 10/21
9:00 am-6:37 pm
1 stop9h 37m
Panama City Tocumen Intl
Wed 10/28
9:30 am-10:50 am
2 stops25h 20m
$636
Showing 1-10 of 42 resultsSorted by cheapest first
Best time to book a flight from Mississippi to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Mississippi with our price prediction graph.
GPT-PTY
BTR-PTY
MOB-PTY
MEM-PTY
JAN-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to Panama
USMS-PA0
GPT-PTY
BTR-PTY
MOB-PTY
MEM-PTY
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Mississippi to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Mississippi to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mississippi to Panama by cabin class
Find flights from Mississippi to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mississippi and Panama flights
Browse other Mississippi and Panama flight options. Last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Panama
Find the right flight back to Mississippi after your stay in Panama
Mississippi to Panama flights
Consider these flights traveling from Mississippi to Panama.
Top airline flying from Mississippi to Panama
Discover the top airline that operate flights from Mississippi to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$524 | Average$786 | FlexibilityNo cancel fee | On-time69% |