HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Iowa

$110+ Cheap flights from South Carolina to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
Jul 7 — Jul 141
Mon 7/7
Mon 7/14
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Iowa

Keep the following information in mind while searching for South Carolina to Iowa flight deals. Data was last updated July 2, 2025.

Round-trip from

$204
(Mytrip)

One-way from

$110
(FlightHub)
From South Carolina to Iowa
Search Deals
One-way flight from South Carolina to Iowa
Search Deals

Find flight deals from South Carolina to Iowa

Cheapest flights from South Carolina to Iowa
Explore the most affordable flight options available from South Carolina to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/19:24 amCLT - CID
1 stop4h 42mMultiple Airlines
Fri 8/16:52 pmCID - CLT
1 stop12h 34mMultiple Airlines
Deal found 7/2$204
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/89:24 amCLT - DSM
1 stop9h 41mMultiple Airlines
Mon 8/111:59 pmDSM - CLT
2 stops22h 41mMultiple Airlines
Deal found 7/1$209
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/75:05 pmCLT - OMA
1 stop6h 20mSouthwest
Mon 8/117:00 amOMA - CLT
1 stop4h 30mSouthwest
Deal found 6/30$236
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/118:37 pmGSP - OMA
1 stop4h 29mAmerican Airlines
Mon 9/153:47 pmOMA - GSP
1 stop5h 43mAmerican Airlines
Deal found 6/30$237
This Gotogate deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/215:32 pmCLT - OMA
1 stop27h 18mFrontier
Sat 8/233:18 pmOMA - CLT
1 stop24h 19mFrontier
Deal found 6/30$237
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/195:25 pmCLT - DSM
1 stop5h 55mSouthwest
Wed 8/206:30 amDSM - CLT
2 stops8h 30mSouthwest
Deal found 6/30$242
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/146:06 pmCHS - CID
1 stop6h 53mAmerican Airlines
Mon 8/186:01 amCID - CHS
1 stop6h 16mAmerican Airlines
Deal found 7/1$249
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/213:23 pmCAE - DSM
1 stop8h 34mAmerican Airlines
Sun 8/247:14 amDSM - CAE
1 stop7h 06mAmerican Airlines
Deal found 6/30$249
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:40 amCAE - OMA
1 stop4h 54mDelta
Mon 9/156:00 amOMA - CAE
1 stop8h 05mDelta
Deal found 7/2$259
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/75:20 pmCLT - CID
1 stop27h 11mFrontier
Thu 9/118:16 pmCID - CLT
1 stop19h 09mFrontier
Deal found 7/1$280
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/24:35 pmCLT - OMA
1 stop8h 11mAmerican Airlines
Tue 10/77:20 pmOMA - CLT
1 stop12h 03mAmerican Airlines
Deal found 7/1$283
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/41:50 pmGSP - OMA
2 stops9h 35mSouthwest
Sun 9/71:05 pmOMA - GSP
1 stop5h 10mSouthwest
Deal found 7/2$286

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
Use the filters below to find and compare flights from South Carolina to Iowa that are best for you.

Fly from

South Carolina

Fly to

Iowa

Route

Depart

Return

Price

CharlotteCedar Rapids

CLT - CID

CLTCID

Charlotte Douglas

Fri 8/1

9:24 am-1:06 pm

1 stop4h 42m

Cedar Rapids

Fri 8/1

6:52 pm-8:26 am

1 stop12h 34m

$204

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 8/8

9:24 am-6:05 pm

1 stop9h 41m

Des Moines

Mon 8/11

1:59 pm-1:40 pm

2 stops22h 41m

$209

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Thu 8/7

5:05 pm-10:25 pm

1 stop6h 20m

Omaha Eppley Airfield

Mon 8/11

7:00 am-12:30 pm

1 stop4h 30m

$236

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

Thu 9/11

8:37 pm-12:06 am

1 stop4h 29m

Omaha Eppley Airfield

Mon 9/15

3:47 pm-10:30 pm

1 stop5h 43m

$237

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Thu 8/21

5:32 pm-7:50 pm

1 stop27h 18m

Omaha Eppley Airfield

Sat 8/23

3:18 pm-4:37 pm

1 stop24h 19m

$237

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 8/19

5:25 pm-10:20 pm

1 stop5h 55m

Des Moines

Wed 8/20

6:30 am-4:00 pm

2 stops8h 30m

$242

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Thu 8/14

6:06 pm-11:59 pm

1 stop6h 53m

Cedar Rapids

Mon 8/18

6:01 am-1:17 pm

1 stop6h 16m

$249

ColumbiaDes Moines

CAE - DSM

CAEDSM

Columbia Metropolitan

Thu 8/21

3:23 pm-10:57 pm

1 stop8h 34m

Des Moines

Sun 8/24

7:14 am-3:20 pm

1 stop7h 06m

$249

ColumbiaOmaha

CAE - OMA

CAEOMA

Columbia Metropolitan

Sat 9/13

5:40 am-9:34 am

1 stop4h 54m

Omaha Eppley Airfield

Mon 9/15

6:00 am-3:05 pm

1 stop8h 05m

$259

CharlotteCedar Rapids

CLT - CID

CLTCID

Charlotte Douglas

Sun 9/7

5:20 pm-7:31 pm

1 stop27h 11m

Cedar Rapids

Thu 9/11

8:16 pm-4:25 pm

1 stop19h 09m

$280

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 57 results
1
2
3
...
6

Best time to book a flight from South Carolina to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Iowa

What is the cheapest month to book a flight from South Carolina to Iowa?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $336). Flying from South Carolina to Iowa in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IA?

Find hourly flight availability from South Carolina to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Iowa as you normally would.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated July 2, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from South Carolina to Iowa have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,272 reviews

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,272 reviews
Southwest
8.0
Very good
4,272 reviews

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,983 reviews
Southwest
8.0
Very good
4,272 reviews

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,861 reviews
Southwest
8.0
Very good
4,272 reviews

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,272 reviews

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Allegiant Air
7.2
Good
709 reviews
Southwest
8.0
Very good
4,272 reviews

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Iowa one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $110. Southwest flights start at $118 while deals on American Airlines start at $126 one-way.

  • Can I find deals for flights from South Carolina to Iowa that include hotel bookings?

    Yes. In addition to deals on South Carolina to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Iowa.

  • Can I find deals for business class flights from South Carolina to Iowa?

    Yes. Cheapflights offers flight deals from South Carolina to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Iowa?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $336). Flying from South Carolina to Iowa in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to LaGuardia flights
Dallas/Fort Worth to Seattle flights
Los Angeles to John F Kennedy Intl flights
John F Kennedy Intl to Los Angeles flights
Los Angeles to Seattle flights
Dallas/Fort Worth to O'Hare Intl flights
Dallas/Fort Worth to John F Kennedy Intl flights
John F Kennedy Intl to Las Vegas flights
Los Angeles to Newark flights
Newark to Los Angeles flights
John F Kennedy Intl to O'Hare Intl flights
LaGuardia to Dallas/Fort Worth flights
Atlanta to John F Kennedy Intl flights
John F Kennedy Intl to Miami flights
Newark to Miami flights
Newark to O'Hare Intl flights
Los Angeles to Honolulu flights
O'Hare Intl to LaGuardia flights
John F Kennedy Intl to Atlanta flights
San Francisco to John F Kennedy Intl flights
John F Kennedy Intl to Seattle flights
Newark to Fort Lauderdale flights
Dallas/Fort Worth to Los Angeles flights
Los Angeles to Dallas/Fort Worth flights
LaGuardia to O'Hare Intl flights
LaGuardia to Fort Lauderdale flights
Los Angeles to San Francisco flights
John F Kennedy Intl to Orlando flights
Dallas/Fort Worth to Las Vegas flights
LaGuardia to Atlanta flights
San Francisco to Los Angeles flights
John F Kennedy Intl to San Francisco flights
San Francisco to Las Vegas flights
O'Hare Intl to John F Kennedy Intl flights
John F Kennedy Intl to Dallas/Fort Worth flights
O'Hare Intl to Newark flights
LaGuardia to Miami flights
O'Hare Intl to Dallas/Fort Worth flights
Ontario to Seattle flights
Newark to Seattle flights
Seattle to Los Angeles flights
Los Angeles to O'Hare Intl flights
O'Hare Intl to Las Vegas flights
San Francisco to Newark flights
Atlanta to LaGuardia flights
Seattle to Dallas/Fort Worth flights
John F Kennedy Intl to Denver flights
Atlanta to Las Vegas flights
Dallas/Fort Worth to Orlando flights
Atlanta to Miami flights

Top 3 airlines flying from South Carolina to Iowa

Discover the top 3 airlines that operate flights from South Carolina to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$204Average$393FlexibilityNo cancel feeOn-time71%
DeltaCheapest$242Average$339FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$336Average$571FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.