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$304+ Cheap flights from Ohio to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — FLO
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Ohio to Florence

Keep the following information in mind while searching for Ohio to Florence flight deals. Data was last updated July 30, 2025.

Round-trip from

$366
(American Airlines)

One-way from

$304
(American Airlines)
From Ohio to Florence
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One-way flight from Ohio to Florence
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Find flight deals from Ohio to Florence

Cheapest flights from Ohio to Florence
Explore the most affordable flight options available from Ohio to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/261:26 pmCLE - FLO
2 stops9h 36mAmerican Airlines
Tue 9/212:11 pmFLO - CLE
2 stops11h 11mAmerican Airlines
Deal found 7/29$366
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/124:19 pmDTW - FLO
1 stop6h 43mAmerican Airlines
Sat 8/162:34 pmFLO - DTW
1 stop3h 52mAmerican Airlines
Deal found 7/28$441
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/126:00 amCVG - FLO
1 stop5h 46mAmerican Airlines
Sat 8/162:34 pmFLO - CVG
1 stop6h 22mAmerican Airlines
Deal found 7/28$441
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/286:17 amCAK - FLO
2 stops29h 45mAmerican Airlines
Mon 10/62:29 pmFLO - CAK
2 stops23h 51mAmerican Airlines
Deal found 7/29$466
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/76:00 amCMH - FLO
1 stop4h 53mAmerican Airlines
Sat 9/136:14 amFLO - CMH
1 stop6h 22mAmerican Airlines
Deal found 7/29$475
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:38 amDAY - FLO
1 stop5h 30mAmerican Airlines
Sat 12/1311:14 amFLO - DAY
1 stop4h 53mAmerican Airlines
Deal found 7/29$475
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1311:14 amPIT - FLO
1 stop3h 50mAmerican Airlines
Sun 8/175:09 amFLO - PIT
1 stop4h 26mAmerican Airlines
Deal found 7/29$509

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Ohio to Florence that are best for you.

Fly from

Ohio

Fly to

Florence

Route

Depart

Return

Price

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 8/26

1:26 pm-11:02 pm

2 stops9h 36m

Florence

Tue 9/2

12:11 pm-11:22 pm

2 stops11h 11m

$366

DetroitFlorence

DTW - FLO

DTWFLO

Detroit Metropolitan Wayne County

Tue 8/12

4:19 pm-11:02 pm

1 stop6h 43m

Florence

Sat 8/16

2:34 pm-6:26 pm

1 stop3h 52m

$441

CincinnatiFlorence

CVG - FLO

CVGFLO

Cincinnati Cinci./N. Kentucky

Tue 8/12

6:00 am-11:46 am

1 stop5h 46m

Florence

Sat 8/16

2:34 pm-8:56 pm

1 stop6h 22m

$441

AkronFlorence

CAK - FLO

CAKFLO

Akron/Canton

Sun 9/28

6:17 am-12:02 pm

2 stops29h 45m

Florence

Mon 10/6

2:29 pm-2:20 pm

2 stops23h 51m

$466

ColumbusFlorence

CMH - FLO

CMHFLO

Columbus

Sun 9/7

6:00 am-10:53 am

1 stop4h 53m

Florence

Sat 9/13

6:14 am-12:36 pm

1 stop6h 22m

$475

DaytonFlorence

DAY - FLO

DAYFLO

Dayton

Wed 12/10

8:38 am-2:08 pm

1 stop5h 30m

Florence

Sat 12/13

11:14 am-4:07 pm

1 stop4h 53m

$475

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Wed 8/13

11:14 am-3:04 pm

1 stop3h 50m

Florence

Sun 8/17

5:09 am-9:35 am

1 stop4h 26m

$509

DetroitFlorence

DTW - FLO

DTWFLO

Detroit Metropolitan Wayne County

Wed 8/20

9:42 am-11:02 pm

2 stops13h 20m

$304

ColumbusFlorence

CMH - FLO

CMHFLO

Columbus

Sat 8/9

6:02 pm-11:59 pm

1 stop5h 57m

$384

AkronFlorence

CAK - FLO

CAKFLO

Akron/Canton

Fri 9/19

7:39 am-12:02 pm

1 stop4h 23m

$418

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Ohio to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Florence

What is the cheapest month to book a flight from Ohio to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Ohio to Florence, South Carolina (average of $366). Flying from Ohio to Florence, South Carolina in October is currently the most expensive (average of $481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to FLO?

Find hourly flight availability from Ohio to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

When flying from Ohio to Florence, South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated July 30, 2025.
See what other customers who have flown with American Airlines from Ohio to Florence have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Crew

8.0

Comfort

7.2

Overall

7.2

Food

6.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Crew

8.0

Comfort

7.2

Overall

7.2

Food

6.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from Ohio to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Ohio?

    If you book a flight to Florence from Ohio, you will be flying to Florence, which is the city’s only airport. Florence (FLO) is located 2.3 mi from the center of Florence.

  • What are the most popular routes from Ohio to Florence, South Carolina?

    While some choose either Detroit Metropolitan Wayne County - Florence or Akron/Canton - Florence, Columbus - Florence is the most popular route from Ohio to Florence, South Carolina.

  • Can I find deals for flights from Ohio to Florence that include hotel bookings?

    Yes. In addition to deals on Ohio to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Florence.

  • Can I find deals for business class flights from Ohio to Florence?

    Yes. Cheapflights offers flight deals from Ohio to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Ohio to Florence, South Carolina (average of $366). Flying from Ohio to Florence, South Carolina in October is currently the most expensive (average of $481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Alternative routes for Ohio to Florence

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Ohio to Florence

Discover the top airline that operate flights from Ohio to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$356Average$530FlexibilityNo cancel feeOn-time71%

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