$275+ Cheap flights from Ohio to Florence, SC (FLO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/4. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — FLO
Apr 11 — Apr 181
Round-trip
1 adult, Economy
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Find cheap flights from Ohio to Florence with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Ohio to Florence
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Cheapest flights from Ohio to FlorenceExplore the most affordable flight options available from Ohio to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
Explore the most affordable flight options available from Ohio to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:01 am
DTW
- FLO
1 stop4h 09m
American Airlines
Wed 6/32:35 pm
FLO
- DTW
1 stop4h 43m
American Airlines
Deal found 3/9![American Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:06 pm
DTW
- FLO
1 stop4h 15m
American Airlines
Sat 3/286:25 pm
FLO
- DTW
1 stop6h 13m
American Airlines
Deal found 3/9![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2111:36 am
DTW
- FLO
1 stop6h 14m
American Airlines
Sun 3/225:16 am
FLO
- DTW
1 stop4h 09m
American Airlines
Deal found 3/7![American Airlines logo]()
$402
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:22 pm
DTW
- FLO
1 stop6h 41m
American Airlines
Sat 11/711:11 am
FLO
- DTW
1 stop3h 40m
American Airlines
Deal found 3/8![American Airlines logo]()
$413
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:10 am
CLE
- FLO
1 stop6h 01m
American Airlines
Wed 7/155:09 am
FLO
- CLE
1 stop6h 03m
American Airlines
Deal found 3/7![American Airlines logo]()
$461
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:07 am
CVG
- FLO
1 stop4h 43m
American Airlines
Sun 5/35:20 am
FLO
- CVG
1 stop4h 22m
American Airlines
Deal found 3/9![American Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/189:44 am
PIT
- FLO
1 stop4h 26m
American Airlines
Sat 6/205:05 am
FLO
- PIT
1 stop3h 49m
American Airlines
Deal found 3/9![American Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:27 am
DAY
- FLO
2 stops13h 20m
American Airlines
Wed 5/135:20 am
FLO
- DAY
2 stops10h 21m
American Airlines
Deal found 3/10![American Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:05 am
CLE
- FLO
1 stop5h 45m
American Airlines
Sun 5/105:20 am
FLO
- CLE
1 stop3h 55m
American Airlines
Deal found 3/9![American Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:31 am
CMH
- FLO
1 stop3h 38m
American Airlines
Sat 8/2911:15 am
FLO
- CMH
1 stop6h 17m
American Airlines
Deal found 3/8![American Airlines logo]()
$519
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:37 pm
CVG
- FLO
2 stops9h 10m
American Airlines
Sat 5/25:20 am
FLO
- CVG
1 stop4h 22m
American Airlines
Deal found 3/9![American Airlines logo]()
$520
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/189:44 am
PIT
- FLO
1 stop4h 26m
American Airlines
Sun 6/285:05 am
FLO
- PIT
1 stop3h 49m
American Airlines
Deal found 3/9![American Airlines logo]()
$521
Best flights from Ohio to FlorenceDiscover carefully curated flight deals from Ohio to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
Discover carefully curated flight deals from Ohio to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:57 pm
DTW
- FLO
2 stops9h 03m
American Airlines
Wed 6/32:35 pm
FLO
- DTW
2 stops7h 59m
American Airlines
Deal found 3/9![American Airlines logo]()
$313
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:06 pm
DTW
- FLO
1 stop4h 15m
American Airlines
Sat 3/286:25 pm
FLO
- DTW
1 stop6h 13m
American Airlines
Deal found 3/9![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:10 am
CLE
- FLO
1 stop6h 01m
American Airlines
Wed 7/155:09 am
FLO
- CLE
1 stop6h 03m
American Airlines
Deal found 3/7![American Airlines logo]()
$461
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:07 am
CVG
- FLO
1 stop4h 43m
American Airlines
Sun 5/35:20 am
FLO
- CVG
1 stop4h 22m
American Airlines
Deal found 3/9![American Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/189:44 am
PIT
- FLO
1 stop4h 26m
American Airlines
Sat 6/205:05 am
FLO
- PIT
1 stop3h 49m
American Airlines
Deal found 3/9![American Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:27 am
DAY
- FLO
2 stops13h 20m
American Airlines
Wed 5/135:20 am
FLO
- DAY
2 stops10h 21m
American Airlines
Deal found 3/10![American Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:05 am
CLE
- FLO
1 stop5h 45m
American Airlines
Sun 5/105:20 am
FLO
- CLE
1 stop3h 55m
American Airlines
Deal found 3/8![American Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:35 pm
CVG
- FLO
1 stop6h 12m
American Airlines
Sun 5/35:20 am
FLO
- CVG
2 stops9h 18m
American Airlines
Deal found 3/9![American Airlines logo]()
$520
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/189:44 am
PIT
- FLO
1 stop4h 26m
American Airlines
Sun 6/285:05 am
FLO
- PIT
1 stop3h 49m
American Airlines
Deal found 3/9![American Airlines logo]()
$521
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:11 am
CVG
- FLO
2 stops10h 36m
American Airlines
Sat 5/25:20 am
FLO
- CVG
2 stops9h 18m
American Airlines
Deal found 3/9![American Airlines logo]()
$525
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:26 am
CVG
- FLO
2 stops12h 21m
American Airlines
Sat 5/24:16 pm
FLO
- CVG
2 stops7h 11m
American Airlines
Deal found 3/9![American Airlines logo]()
$525
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:05 pm
DAY
- FLO
1 stop4h 03m
American Airlines
Sat 3/285:16 am
FLO
- DAY
2 stops6h 55m
American Airlines
Deal found 3/9![American Airlines logo]()
$526
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:08 am
PIT
- FLO
1 stop4h 24m
American Airlines
Tue 5/56:15 am
FLO
- PIT
2 stops13h 09m
American Airlines
Deal found 3/10![American Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:58 pm
PIT
- FLO
1 stop3h 49m
American Airlines
Tue 5/56:15 am
FLO
- PIT
2 stops13h 09m
American Airlines
Deal found 3/10![American Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:33 am
PIT
- FLO
1 stop5h 17m
American Airlines
Sun 5/34:16 pm
FLO
- PIT
1 stop4h 42m
American Airlines
Deal found 3/10![American Airlines logo]()
$535
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/183:35 pm
CVG
- FLO
1 stop6h 12m
American Airlines
Sun 5/312:35 pm
FLO
- CVG
2 stops9h 24m
American Airlines
Deal found 3/7![American Airlines logo]()
$540
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:58 pm
PIT
- FLO
1 stop3h 49m
American Airlines
Tue 5/56:15 am
FLO
- PIT
2 stops6h 24m
American Airlines
Deal found 3/10![American Airlines logo]()
$540
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/274:52 pm
PIT
- FLO
2 stops7h 05m
American Airlines
Tue 3/316:15 am
FLO
- PIT
1 stop4h 07m
American Airlines
Deal found 3/8![American Airlines logo]()
$564
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:30 pm
DAY
- FLO
1 stop4h 27m
American Airlines
Sat 3/285:16 am
FLO
- DAY
2 stops6h 55m
American Airlines
Deal found 3/7![American Airlines logo]()
$565
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:55 am
CMH
- FLO
1 stop5h 55m
American Airlines
Sun 3/295:16 am
FLO
- CMH
1 stop5h 54m
American Airlines
Deal found 3/10![American Airlines logo]()
$580
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:43 pm
CMH
- FLO
1 stop6h 14m
American Airlines
Mon 4/66:20 pm
FLO
- CMH
1 stop6h 06m
American Airlines
Deal found 3/8![American Airlines logo]()
$599
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:20 am
DTW
- FLO
2 stops11h 30m
American Airlines
Mon 3/306:20 pm
FLO
- DTW
1 stop6h 16m
American Airlines
Deal found 3/11![American Airlines logo]()
$638
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:55 pm
DTW
- FLO
1 stop4h 02m
American Airlines
Thu 3/265:16 am
FLO
- DTW
2 stops11h 32m
American Airlines
Deal found 3/9![American Airlines logo]()
$643
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:57 am
PIT
- FLO
2 stops7h 53m
American Airlines
Sun 3/295:16 am
FLO
- PIT
2 stops8h 27m
American Airlines
Deal found 3/12![American Airlines logo]()
$678
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2212:41 pm
DAY
- FLO
2 stops11h 16m
American Airlines
Fri 3/276:20 pm
FLO
- DAY
2 stops22h 45m
American Airlines
Deal found 3/7![American Airlines logo]()
$814
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/237:55 pm
DTW
- FLO
1 stop4h 02m
American Airlines
Fri 3/276:20 pm
FLO
- DTW
1 stop15h 00m
American Airlines
Deal found 3/8![American Airlines logo]()
$827
Last-minute flights from Ohio to FlorenceDiscover last-minute flight deals from Ohio to Florence. Data last updated March 12, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to Florence. Data last updated March 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1111:51 am
CAK
- FLO
1 stop5h 59m
American Airlines
Wed 3/185:16 am
FLO
- CAK
1 stop5h 59m
American Airlines
Deal found 3/8![American Airlines logo]()
$521
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2111:36 am
DTW
- FLO
1 stop6h 14m
American Airlines
Sun 3/225:16 am
FLO
- DTW
1 stop4h 09m
American Airlines
Deal found 3/7![American Airlines logo]()
$402
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/217:57 pm
CVG
- FLO
1 stop4h 00m
American Airlines
Sat 3/285:16 am
FLO
- CVG
1 stop4h 45m
American Airlines
Deal found 3/7![American Airlines logo]()
$521
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/211:54 pm
DAY
- FLO
1 stop3h 56m
American Airlines
Sat 3/285:16 am
FLO
- DAY
2 stops6h 55m
American Airlines
Deal found 3/7![American Airlines logo]()
$526
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:06 pm
DTW
- FLO
1 stop4h 15m
American Airlines
Sat 3/286:25 pm
FLO
- DTW
1 stop6h 13m
American Airlines
Deal found 3/9![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/273:50 pm
PIT
- FLO
2 stops8h 07m
American Airlines
Tue 3/316:15 am
FLO
- PIT
2 stops12h 51m
American Airlines
Deal found 3/8![American Airlines logo]()
$555
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:08 am
PIT
- FLO
1 stop4h 24m
American Airlines
Tue 5/56:15 am
FLO
- PIT
2 stops13h 09m
American Airlines
Deal found 3/10![American Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:04 pm
PIT
- FLO
1 stop6h 38m
American Airlines
Mon 5/45:20 am
FLO
- PIT
1 stop4h 23m
American Airlines
Deal found 3/10![American Airlines logo]()
$535
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:07 am
CVG
- FLO
1 stop4h 43m
American Airlines
Sun 5/35:20 am
FLO
- CVG
1 stop4h 22m
American Airlines
Deal found 3/9![American Airlines logo]()
$515
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:37 pm
CVG
- FLO
2 stops9h 10m
American Airlines
Sat 5/25:20 am
FLO
- CVG
1 stop4h 22m
American Airlines
Deal found 3/9![American Airlines logo]()
$520
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:24 am
PIT
- FLO
2 stops7h 26m
American Airlines
Tue 5/54:02 pm
FLO
- PIT
2 stops7h 19m
American Airlines
Deal found 3/10![American Airlines logo]()
$539
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:54 am
PIT
- FLO
2 stops8h 56m
American Airlines
Mon 5/45:20 am
FLO
- PIT
2 stops10h 11m
American Airlines
Deal found 3/10![American Airlines logo]()
$545
One-way flights from Ohio to FlorenceSearch for one-way flight options from Ohio to Florence. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
Search for one-way flight options from Ohio to Florence. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:00 am
CLE
- FLO
2 stops12h 50m
American Airlines
Deal found 3/8![American Airlines logo]()
$275
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:20 am
DTW
- FLO
2 stops11h 40m
American Airlines
Deal found 3/9![American Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:00 am
CVG
- FLO
2 stops12h 21m
American Airlines
Deal found 3/10![American Airlines logo]()
$302
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:00 am
CLE
- FLO
2 stops12h 50m
American Airlines
Deal found 3/9![American Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/189:44 am
PIT
- FLO
1 stop4h 26m
American Airlines
Deal found 3/9![American Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:40 pm
CAK
- FLO
1 stop5h 17m
American Airlines
Deal found 3/9![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/211:51 am
CAK
- FLO
1 stop5h 59m
American Airlines
Deal found 3/9![American Airlines logo]()
$458
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:55 pm
CLE
- FLO
1 stop5h 02m
American Airlines
Deal found 3/9![American Airlines logo]()
$458
Find flight deals from Ohio to Florence
Keep the following information in mind while searching for Ohio to Florence flight deals. Data was last updated March 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $303 (American Airlines) |
One-way from | $275 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from Ohio to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitFlorence
DTW - FLO
DTWFLO
Detroit Metropolitan Wayne County
Sat 5/23
12:57 pm-10:00 pm
2 stops9h 03m
Florence
Wed 6/3
2:35 pm-10:34 pm
2 stops7h 59m
$313
DetroitFlorence
DTW - FLO
DTWFLO
Detroit Metropolitan Wayne County
Tue 3/24
1:06 pm-5:21 pm
1 stop4h 15m
Florence
Sat 3/28
6:25 pm-12:38 am
1 stop6h 13m
$375
ClevelandFlorence
CLE - FLO
CLEFLO
Cleveland Hopkins Intl
Tue 7/7
8:10 am-2:11 pm
1 stop6h 01m
Florence
Wed 7/15
5:09 am-11:12 am
1 stop6h 03m
$461
CincinnatiFlorence
CVG - FLO
CVGFLO
Cincinnati Cinci./N. Kentucky
Wed 4/29
11:07 am-3:50 pm
1 stop4h 43m
Florence
Sun 5/3
5:20 am-9:42 am
1 stop4h 22m
$515
Quickest round-trip
PittsburghFlorence
PIT - FLO
PITFLO
Pittsburgh
Thu 6/18
9:44 am-2:10 pm
1 stop4h 26m
Florence
Sat 6/20
5:05 am-8:54 am
1 stop3h 49m
$515
DaytonFlorence
DAY - FLO
DAYFLO
Dayton
Fri 5/8
8:27 am-9:47 pm
2 stops13h 20m
Florence
Wed 5/13
5:20 am-3:41 pm
2 stops10h 21m
$515
ClevelandFlorence
CLE - FLO
CLEFLO
Cleveland Hopkins Intl
Thu 5/7
10:05 am-3:50 pm
1 stop5h 45m
Florence
Sun 5/10
5:20 am-9:15 am
1 stop3h 55m
$515
CincinnatiFlorence
CVG - FLO
CVGFLO
Cincinnati Cinci./N. Kentucky
Thu 4/30
3:35 pm-9:47 pm
1 stop6h 12m
Florence
Sun 5/3
5:20 am-2:38 pm
2 stops9h 18m
$520
PittsburghFlorence
PIT - FLO
PITFLO
Pittsburgh
Thu 6/18
9:44 am-2:10 pm
1 stop4h 26m
Florence
Sun 6/28
5:05 am-8:54 am
1 stop3h 49m
$521
CincinnatiFlorence
CVG - FLO
CVGFLO
Cincinnati Cinci./N. Kentucky
Wed 4/29
11:11 am-9:47 pm
2 stops10h 36m
Florence
Sat 5/2
5:20 am-2:38 pm
2 stops9h 18m
$525
Showing 1-10 of 35 resultsSorted by cheapest first
Best time to book a flight from Ohio to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Ohio with our price prediction graph.
DTW-FLO
CVG-FLO
CAK-FLO
DAY-FLO
PIT-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to Florence
USOH-FLO
DTW-FLO
CVG-FLO
CAK-FLO
DAY-FLO
What is the cheapest month to book a flight from Ohio to Florence, South Carolina?
Currently, October is the cheapest month in which you can book a flight from Ohio to Florence, South Carolina (average of $41). Flying from Ohio to Florence, South Carolina in February is currently the most expensive (average of $88). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Ohio to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Florence?
Book flights to Florence if you plan to visit one of these locationsSumter
Hartsville
Darlington
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Ohio to Florence
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Complete your trip
Complete your trip to Florence by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Ohio to Florence by cabin class
Find flights from Ohio to Florence, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Florence
Explore flights to Florence departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 12, 2026.
Ohio and Florence flights
Browse other Ohio and Florence flight options. Last updated on March 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Ohio to Florence flights
Consider these flights traveling from Ohio to Florence.
Top airline flying from Ohio to Florence
Discover the top airline that operate flights from Ohio to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$474 | Average$578 | FlexibilityNo cancel fee | On-time71% |