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$346+ Cheap flights from Florence, SC (FLO) to Ohio

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/19. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — CLE
Jul 24 — Jul 311
Fri 7/24
Fri 7/31
1 adult, Economy
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Cheap flight deals from Florence to Ohio

Cheapest flights from Florence to Ohio
Explore the most affordable flight options available from Florence to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 24, 2026.

This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:17 am
FLO
-
PIT
2 stops11h 00m
American Airlines
Tue 8/41:01 pm
PIT
-
FLO
2 stops10h 36m
American Airlines
Deal found 6/23$411
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:17 am
FLO
-
CVG
1 stop3h 24m
American Airlines
Tue 7/2812:04 pm
CVG
-
FLO
2 stops11h 33m
American Airlines
Deal found 6/23$511
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:17 am
FLO
-
PIT
1 stop4h 13m
American Airlines
Sat 7/118:01 pm
PIT
-
FLO
1 stop3h 36m
American Airlines
Deal found 6/22$529
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:17 am
FLO
-
CAK
1 stop4h 01m
American Airlines
Sat 7/118:33 am
CAK
-
FLO
1 stop5h 37m
American Airlines
Deal found 6/22$541
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:17 am
FLO
-
DTW
1 stop4h 00m
American Airlines
Sun 7/2610:00 am
DTW
-
FLO
1 stop4h 10m
American Airlines
Deal found 6/20$555
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:17 am
FLO
-
DAY
2 stops14h 13m
American Airlines
Sat 7/117:19 am
DAY
-
FLO
2 stops16h 18m
American Airlines
Deal found 6/22$558
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:17 am
FLO
-
CVG
2 stops10h 31m
American Airlines
Mon 7/205:29 pm
CVG
-
FLO
1 stop6h 08m
American Airlines
Deal found 6/23$580
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:35 pm
FLO
-
DTW
1 stop4h 38m
American Airlines
Sun 7/1210:00 am
DTW
-
FLO
1 stop4h 10m
American Airlines
Deal found 6/23$619
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:17 am
FLO
-
CVG
2 stops13h 20m
American Airlines
Thu 7/912:04 pm
CVG
-
FLO
2 stops11h 33m
American Airlines
Deal found 6/19$869

Find flight deals from Florence to Ohio

Keep the following information in mind while searching for Florence to Ohio flight deals. Data was last updated June 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$411
(American Airlines)

One-way from

$346
(American Airlines)
Provider with most accurate pricing for Florence-Cleveland Hopkins Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Cleveland Hopkins Intl flights.
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From Florence to Ohio
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One-way flight from Florence to Ohio
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
Use the filters below to find and compare flights from Florence to Ohio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

FlorencePittsburgh

FLO - PIT

FLOPIT

Florence

Sat 8/1

5:17 am-9:30 am

1 stop4h 13m

Pittsburgh

Tue 8/4

1:01 pm-11:37 pm

2 stops10h 36m

$419

FlorenceCincinnati

FLO - CVG

FLOCVG

Florence

Tue 7/21

5:17 am-8:41 am

1 stop3h 24m

Cincinnati Cinci./N. Kentucky

Tue 7/28

5:29 pm-11:37 pm

1 stop6h 08m

$511
Quickest round-trip

FlorencePittsburgh

FLO - PIT

FLOPIT

Florence

Tue 7/7

5:17 am-9:30 am

1 stop4h 13m

Pittsburgh

Sat 7/11

8:01 pm-11:37 pm

1 stop3h 36m

$529

FlorenceAkron

FLO - CAK

FLOCAK

Florence

Tue 7/7

5:17 am-9:18 am

1 stop4h 01m

Akron/Canton

Sat 7/11

8:33 am-2:10 pm

1 stop5h 37m

$541

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Fri 7/24

5:17 am-9:17 am

1 stop4h 00m

Detroit Metropolitan Wayne County

Sun 7/26

10:00 am-2:10 pm

1 stop4h 10m

$555

FlorenceDayton

FLO - DAY

FLODAY

Florence

Tue 7/7

5:17 am-7:30 pm

2 stops14h 13m

Dayton

Sat 7/11

7:19 am-11:37 pm

2 stops16h 18m

$558

FlorenceCincinnati

FLO - CVG

FLOCVG

Florence

Wed 7/15

5:17 am-3:48 pm

2 stops10h 31m

Cincinnati Cinci./N. Kentucky

Mon 7/20

5:29 pm-11:37 pm

1 stop6h 08m

$580

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Wed 7/8

2:35 pm-7:13 pm

1 stop4h 38m

Detroit Metropolitan Wayne County

Sun 7/12

10:00 am-2:10 pm

1 stop4h 10m

$619

FlorenceCincinnati

FLO - CVG

FLOCVG

Florence

Sun 7/5

5:17 am-8:32 am

1 stop3h 15m

Cincinnati Cinci./N. Kentucky

Thu 7/9

5:29 pm-11:37 pm

1 stop6h 08m

$955
Cheapest one-way

FlorenceAkron

FLO - CAK

FLOCAK

Florence

Sun 7/19

2:35 pm-8:40 pm

1 stop6h 05m

$346

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/21

Showing 1-10 of 18 resultsSorted by cheapest first
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Best time to book a flight from Florence to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Ohio
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Florence to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Ohio?

    Most people fly from Florence (FLO) if they book a flight from Florence to Ohio. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Florence, South Carolina to Ohio?

    There are many flights that can get you from Florence, South Carolina to Ohio in 4h 13m. Fly via American Airlines to get the fastest option. The distance between Florence, South Carolina and Ohio is about 437 mi.

  • What are the most popular routes from Florence, South Carolina to Ohio?

    The most popular flight routes from Florence, South Carolina to Ohio are Florence - Cincinnati Cinci./N. Kentucky, Florence - Pittsburgh and Florence - Akron/Canton.

  • Can I find deals for flights from Florence to Ohio that include hotel bookings?

    Yes. In addition to deals on Florence to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Ohio.

  • Can I find deals for business class flights from Florence to Ohio?

    Yes. Cheapflights offers flight deals from Florence to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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