$620+ Cheap flights from Ohio to Florence, SC (FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — FLO
Oct 29 — Nov 51
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Ohio to Florence
Cheapest
Best
Last-minute
Cheapest flights from Ohio to FlorenceExplore the most affordable flight options available from Ohio to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
Explore the most affordable flight options available from Ohio to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:10 am -
1 stop5h 59m
Sun 10/185:09 am -
1 stop6h 00m
Deal found 9/29![American Airlines logo]()
$620
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:25 pm -
1 stop6h 32m
Tue 10/133:19 pm -
1 stop6h 21m
Deal found 9/24![American Airlines logo]()
$649
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:39 am -
1 stop3h 39m
Sun 10/42:36 pm -
1 stop4h 16m
Deal found 9/27![American Airlines logo]()
$669
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:39 am -
1 stop3h 39m
Mon 10/52:34 pm -
1 stop3h 54m
Deal found 9/24![American Airlines logo]()
$722
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:39 am -
1 stop3h 39m
Sat 10/36:24 am -
1 stop6h 05m
Deal found 9/27![American Airlines logo]()
$730
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:39 am -
1 stop3h 39m
Sun 10/45:09 am -
1 stop6h 19m
Deal found 9/27![American Airlines logo]()
$779
Best flights from Ohio to FlorenceDiscover carefully curated flight deals from Ohio to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
Discover carefully curated flight deals from Ohio to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:10 am -
1 stop5h 59m
Sun 10/185:09 am -
1 stop6h 00m
Deal found 9/29![American Airlines logo]()
$620
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:25 pm -
1 stop6h 32m
Tue 10/133:19 pm -
1 stop6h 21m
Deal found 9/24![American Airlines logo]()
$649
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/115:25 pm -
1 stop6h 32m
Thu 10/152:34 pm -
1 stop3h 54m
Deal found 9/26![American Airlines logo]()
$985
Last-minute flights from Ohio to FlorenceDiscover last-minute flight deals from Ohio to Florence. Data last updated September 29, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to Florence. Data last updated September 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:39 am -
1 stop3h 39m
Sun 10/42:36 pm -
1 stop4h 16m
Deal found 9/27![American Airlines logo]()
$669
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:39 am -
1 stop3h 39m
Sat 10/36:24 am -
1 stop6h 05m
Deal found 9/27![American Airlines logo]()
$730
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:39 am -
1 stop3h 39m
Mon 10/52:34 pm -
1 stop3h 54m
Deal found 9/24![American Airlines logo]()
$722
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:39 am -
1 stop3h 39m
Sun 10/45:09 am -
1 stop6h 19m
Deal found 9/27![American Airlines logo]()
$779
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:25 pm -
1 stop6h 32m
Tue 10/133:19 pm -
1 stop6h 21m
Deal found 9/24![American Airlines logo]()
$649
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:10 am -
1 stop5h 59m
Sun 10/185:09 am -
1 stop6h 00m
Deal found 9/29![American Airlines logo]()
$620
Find flight deals from Ohio to Florence
Keep the following information in mind while searching for Ohio to Florence flight deals. Data was last updated September 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $620 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
Use the filters below to find and compare flights from Ohio to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandFlorence
CLE Cleveland Hopkins Intl - FLO Florence
CLEFLO
Cleveland Hopkins Intl
Wed 10/14
8:10 am-2:09 pm
1 stop5h 59m
Florence
Sun 10/18
5:09 am-11:09 am
1 stop6h 00m
$620
ClevelandFlorence
CLE Cleveland Hopkins Intl - FLO Florence
CLEFLO
Cleveland Hopkins Intl
Fri 10/9
5:25 pm-11:57 pm
1 stop6h 32m
Florence
Tue 10/13
3:19 pm-9:40 pm
1 stop6h 21m
$649
Quickest round-trip
ClevelandFlorence
CLE Cleveland Hopkins Intl - FLO Florence
CLEFLO
Cleveland Hopkins Intl
Sun 10/11
5:25 pm-11:57 pm
1 stop6h 32m
Florence
Thu 10/15
2:34 pm-6:28 pm
1 stop3h 54m
$985
Sorted by cheapest first
Best time to book a flight from Ohio to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Ohio with our price prediction graph.
CLE-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to Florence
USOH-FLO
CLE-FLO
No data available for this route at this time. Please check back soon.
Related info for your journey
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