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South Carolina

$76+ Cheap flights from Iowa to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CHS
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Iowa to South Carolina

Keep the following information in mind while searching for Iowa to South Carolina flight deals. Data was last updated September 17, 2025.

Round-trip from

$198
(Booking.com)

One-way from

$76
(Frontier)

Popular in

October

Cheapest in

August

Average price

$348
From Iowa to South Carolina
Search Deals
One-way flight from Iowa to South Carolina
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Highest demand for flights based on searches. 8% potential increase in price ($37 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Iowa to South Carolina

Cheapest flights from Iowa to South Carolina
Explore the most affordable flight options available from Iowa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:26 pmOMA - CLT
1 stop14h 34mFrontier
Thu 10/165:34 pmCLT - OMA
1 stop27h 30mFrontier
Deal found 9/16$198
This Booking.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1611:31 amOMA - CLT
1 stop19h 29mFrontier
Sun 10/195:34 pmCLT - OMA
1 stop27h 30mFrontier
Deal found 9/17$227
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:40 pmDSM - CLT
1 stop12h 22mAmerican Airlines
Sun 11/911:50 amCLT - DSM
Nonstop2h 41mAmerican Airlines
Deal found 9/16$229
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/12:50 pmCID - CLT
1 stop17h 12mAmerican Airlines
Sun 11/211:40 amCLT - CID
Nonstop2h 39mAmerican Airlines
Deal found 9/15$233
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/54:58 pmCID - CHS
1 stop5h 59mAmerican Airlines
Sat 11/87:53 pmCHS - CID
1 stop5h 03mAmerican Airlines
Deal found 9/15$249
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:39 pmCID - SAV
1 stop4h 20mAmerican Airlines
Mon 10/278:37 pmSAV - CID
1 stop4h 36mAmerican Airlines
Deal found 9/15$249
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1911:29 amCID - SAV
2 stops6h 07mAmerican Airlines
Sun 11/238:32 pmSAV - CID
1 stop4h 24mAmerican Airlines
Deal found 9/16$254
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:00 amMLI - CLT
1 stop6h 27mDelta
Sat 10/1811:41 amCLT - MLI
1 stop5h 39mDelta
Deal found 9/15$257
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:00 amCID - CLT
1 stop6h 27mDelta
Mon 11/34:40 pmCLT - CID
1 stop7h 01mDelta
Deal found 9/15$257
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:32 pmDSM - CLT
1 stop4h 43mDelta
Sun 10/266:00 amCLT - DSM
1 stop4h 20mDelta
Deal found 9/15$257
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1911:29 amCID - CHS
2 stops6h 01mAmerican Airlines
Sun 11/235:15 amCHS - CID
2 stops6h 44mAmerican Airlines
Deal found 9/16$259
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/28:47 pmDSM - CLT
1 stop16h 16mMultiple Airlines
Mon 10/68:51 pmCLT - DSM
2 stops42h 01mMultiple Airlines
Deal found 9/17$262

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Iowa to South Carolina that are best for you.

Fly from

Iowa

Fly to

South Carolina

Route

Depart

Return

Price

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Wed 11/5

3:13 pm-9:50 pm

1 stop5h 37m

Charleston

Sat 11/8

6:40 pm-11:27 pm

1 stop5h 47m

$249

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Tue 10/7

6:00 am-11:09 am

1 stop4h 09m

Savannah/Hilton Head

Sat 10/11

5:37 pm-10:34 pm

1 stop5h 57m

$249

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Wed 11/12

8:00 am-3:11 pm

1 stop6h 11m

Savannah/Hilton Head

Sat 11/15

1:24 pm-7:06 pm

1 stop6h 42m

$249

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Wed 11/19

11:29 am-6:07 pm

1 stop5h 38m

Charleston

Sun 11/23

6:40 pm-11:23 pm

1 stop5h 43m

$249

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Wed 11/5

3:13 pm-9:34 pm

1 stop5h 21m

Savannah/Hilton Head

Sat 11/8

7:37 am-2:28 pm

1 stop7h 51m

$249

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Thu 10/16

6:39 pm-11:59 pm

1 stop4h 20m

Savannah/Hilton Head

Tue 10/21

7:36 am-12:08 pm

1 stop5h 32m

$249

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Fri 10/17

6:39 pm-11:59 pm

1 stop4h 20m

Savannah/Hilton Head

Fri 10/24

12:09 pm-5:45 pm

1 stop6h 36m

$249

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Sat 10/4

5:57 am-1:49 pm

1 stop6h 52m

Charleston

Sat 10/11

6:55 pm-10:34 pm

1 stop4h 39m

$254

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Tue 10/7

11:25 am-11:59 pm

2 stops11h 34m

Savannah/Hilton Head

Sat 10/11

10:10 am-2:12 pm

1 stop5h 02m

$254

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Wed 11/5

12:31 pm-11:43 pm

2 stops10h 12m

Savannah/Hilton Head

Sat 11/8

5:44 pm-10:34 pm

1 stop5h 50m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to South Carolina

What is the cheapest month to book a flight from Iowa to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SC?

Find hourly flight availability from Iowa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from Iowa to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Iowa to South Carolina by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,961 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,926 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Iowa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to South Carolina?

    Airlines like American Airlines, Delta, and United Airlines fly from Iowa to South Carolina in about 4h 09m. The time it takes to get you to your destination can typically vary by up to 2h 02m. The distance between Iowa and South Carolina is about 887 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Iowa to South Carolina one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $113. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Iowa to South Carolina for a low price.

  • Can I find deals for flights from Iowa to South Carolina that include hotel bookings?

    Yes. In addition to deals on Iowa to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to South Carolina.

  • Can I find deals for business class flights from Iowa to South Carolina?

    Yes. Cheapflights offers flight deals from Iowa to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to South Carolina

Discover the top 4 airlines that operate flights from Iowa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$367FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$235Average$422FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$397FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$272Average$404FlexibilityNo cancel feeOn-time63%

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