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South Carolina

$95+ Cheap flights from Iowa to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CHS
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Iowa to South Carolina

Keep the following information in mind while searching for Iowa to South Carolina flight deals. Data was last updated junio 12, 2025.

Round-trip from

$199
(Mytrip)

One-way from

$95
(Mytrip)

Popular in

June

Cheapest in

September

Average price

$481
From Iowa to South Carolina
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One-way flight from Iowa to South Carolina
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Highest demand for flights based on searches. 10% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Iowa to South Carolina

Cheapest flights from Iowa to South Carolina
Explore the most affordable flight options available from Iowa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/66:45 amOMA - CLT
1 stop4h 40mSouthwest
mar. 11/116:20 pmCLT - OMA
1 stop4h 35mSouthwest
Deal found 6/11$181
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/176:32 pmDSM - CLT
1 stop18h 30mMultiple Airlines
jue. 7/2411:40 amCLT - DSM
1 stop28h 05mMultiple Airlines
Deal found 6/10$199
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/252:14 pmDSM - CLT
1 stop7h 06mDelta
jue. 10/28:25 amCLT - DSM
1 stop6h 03mDelta
Deal found 6/12$217
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/1210:53 amOMA - CLT
1 stop4h 34mDelta
mar. 8/196:20 amCLT - OMA
1 stop4h 53mDelta
Deal found 6/12$217
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/218:35 amDSM - MYR
1 stop10h 28mMultiple Airlines
vie. 7/258:34 amMYR - DSM
1 stop7h 11mMultiple Airlines
Deal found 6/10$219
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/218:41 pmDSM - CLT
1 stop18h 51mFrontier
dom. 9/285:34 pmCLT - DSM
1 stop27h 22mFrontier
Deal found 6/10$224
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/286:52 pmCID - CLT
1 stop12h 34mMultiple Airlines
jue. 7/316:20 amCLT - CID
2 stops31h 46mMultiple Airlines
Deal found 6/11$238
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/296:00 amCID - CHS
1 stop6h 56mDelta
lun. 8/46:23 pmCHS - CID
1 stop5h 21mDelta
Deal found 6/12$249
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/126:00 amOMA - CLT
1 stop8h 40mAmerican Airlines
jue. 8/212:45 pmCLT - OMA
1 stop10h 03mAmerican Airlines
Deal found 6/11$255
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/56:01 amCID - CHS
2 stops9h 44mAmerican Airlines
lun. 9/85:36 pmCHS - CID
2 stops7h 06mAmerican Airlines
Deal found 6/11$259
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/146:19 amOMA - MYR
1 stop9h 17mAmerican Airlines
jue. 8/217:00 amMYR - OMA
1 stop7h 07mAmerican Airlines
Deal found 6/12$270
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/236:00 amOMA - CHS
1 stop12h 18mAmerican Airlines
lun. 10/277:57 amCHS - OMA
1 stop6h 03mAmerican Airlines
Deal found 6/11$270

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Iowa to South Carolina that are best for you.

Fly from

Iowa

Fly to

South Carolina

Route

Depart

Return

Price

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

jue. 7/17

6:32 pm-2:02 pm

1 stop18h 30m

Charlotte Douglas

jue. 7/24

11:40 am-2:45 pm

1 stop28h 05m

$199

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

jue. 9/25

2:14 pm-10:20 pm

1 stop7h 06m

Charlotte Douglas

jue. 10/2

8:25 am-1:28 pm

1 stop6h 03m

$217

OmahaCharlotte

OMA - CLT

OMACLT

Omaha Eppley Airfield

mar. 8/12

5:15 am-11:01 am

1 stop4h 46m

Charlotte Douglas

jue. 8/21

6:20 am-12:38 pm

1 stop7h 18m

$217

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

lun. 7/21

8:35 am-8:03 pm

1 stop10h 28m

Myrtle Beach Intl

vie. 7/25

8:34 am-2:45 pm

1 stop7h 11m

$219

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

dom. 9/21

8:41 pm-4:32 pm

1 stop18h 51m

Charlotte Douglas

dom. 9/28

5:34 pm-7:56 pm

1 stop27h 22m

$224

Cedar RapidsCharlotte

CID - CLT

CIDCLT

Cedar Rapids

lun. 7/28

6:52 pm-8:26 am

1 stop12h 34m

Charlotte Douglas

jue. 7/31

6:20 am-1:06 pm

2 stops31h 46m

$238

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

mar. 7/29

6:00 am-1:56 pm

1 stop6h 56m

Charleston

lun. 8/4

6:23 pm-10:44 pm

1 stop5h 21m

$249

OmahaCharlotte

OMA - CLT

OMACLT

Omaha Eppley Airfield

mar. 8/12

6:00 am-3:40 pm

1 stop8h 40m

Charlotte Douglas

jue. 8/21

2:45 pm-11:48 pm

1 stop10h 03m

$255

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

vie. 9/5

6:01 am-4:45 pm

2 stops9h 44m

Charleston

lun. 9/8

5:36 pm-11:42 pm

2 stops7h 06m

$259

OmahaMyrtle Beach

OMA - MYR

OMAMYR

Omaha Eppley Airfield

jue. 8/14

6:19 am-4:36 pm

1 stop9h 17m

Myrtle Beach Intl

jue. 8/21

7:00 am-1:07 pm

1 stop7h 07m

$270

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to South Carolina

What is the cheapest month to book a flight from Iowa to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SC?

Find hourly flight availability from Iowa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

When flying from Iowa to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated junio 12, 2025.
Read through reviews of airlines operating flights from Iowa to South Carolina, such as Southwest, Delta and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Food

7.1

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Food

7.1

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,950 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Food

7.1

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Food

7.1

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Allegiant Air
7.3
Good
725 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Food

7.1

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Food

7.1

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Iowa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Iowa to South Carolina one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $133. However, be on the lookout for offers from Delta and Allegiant Air, as they are both options that can get you from Iowa to South Carolina for a low price.

  • Can I find deals for flights from Iowa to South Carolina that include hotel bookings?

    Yes. In addition to deals on Iowa to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to South Carolina.

  • Can I find deals for business class flights from Iowa to South Carolina?

    Yes. Cheapflights offers flight deals from Iowa to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to South Carolina

Discover the top 4 airlines that operate flights from Iowa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$384FlexibilityNo cancel feeOn-time71%
DeltaCheapest$232Average$359FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$235Average$444FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$376Average$447FlexibilityNo cancel feeOn-time63%

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