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South Carolina

$96+ Cheap flights from Iowa to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CHS
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from Iowa to South Carolina

Keep the following information in mind while searching for Iowa to South Carolina flight deals. Data was last updated April 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$199
(United Airlines)

One-way from

$96
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$316
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From Iowa to South Carolina
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One-way flight from Iowa to South Carolina
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Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Iowa to South Carolina

Cheapest flights from Iowa to South Carolina
Explore the most affordable flight options available from Iowa to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/12:40 pmCID - CHS
1 stop5h 53mUnited Airlines
Fri 7/43:51 pmCHS - CID
1 stop6h 35mUnited Airlines
Deal found 4/29$199
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/17:15 amCID - SAV
1 stop6h 08mAmerican Airlines
Sat 7/57:56 pmSAV - CID
1 stop4h 50mAmerican Airlines
Deal found 4/28$199
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/45:56 amCID - CHS
1 stop4h 57mDelta
Tue 7/86:23 pmCHS - CID
1 stop5h 21mDelta
Deal found 4/29$243
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:25 amCID - SAV
1 stop6h 49mDelta
Tue 6/36:59 pmSAV - CID
1 stop5h 01mDelta
Deal found 4/29$243
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/37:15 amCID - CHS
1 stop4h 39mAmerican Airlines
Mon 7/76:02 pmCHS - CID
1 stop6h 44mAmerican Airlines
Deal found 4/28$249
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/227:15 pmDSM - CLT
1 stop19h 22mMultiple Airlines
Mon 5/266:34 pmCLT - DSM
1 stop22h 02mMultiple Airlines
Deal found 4/29$267
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/302:15 pmDSM - CHS
1 stop5h 33mAmerican Airlines
Tue 10/78:00 pmCHS - DSM
1 stop4h 45mAmerican Airlines
Deal found 4/29$271
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/71:15 pmDSM - MYR
2 stops28h 15mMultiple Airlines
Wed 6/116:00 amMYR - DSM
1 stop8h 33mMultiple Airlines
Deal found 4/29$275
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/3010:17 amDSM - CHS
1 stop6h 43mDelta
Tue 6/34:59 pmCHS - DSM
1 stop6h 31mDelta
Deal found 4/28$284
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/246:30 amDSM - MYR
1 stop4h 22mDelta
Sat 5/316:00 amMYR - DSM
1 stop5h 41mDelta
Deal found 4/28$284
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/47:00 amDSM - CLT
Nonstop2h 21mAmerican Airlines
Fri 7/41:01 pmCLT - DSM
1 stop5h 09mAmerican Airlines
Deal found 4/28$284
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/212:13 pmOMA - SAV
1 stop5h 09mAmerican Airlines
Wed 7/912:43 pmSAV - OMA
1 stop5h 51mAmerican Airlines
Deal found 4/29$285

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Iowa to South Carolina that are best for you.

Fly from

Iowa

Fly to

South Carolina

Route

Depart

Return

Price

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Tue 7/1

2:40 pm-9:33 pm

1 stop5h 53m

Charleston

Fri 7/4

3:51 pm-9:26 pm

1 stop6h 35m

$199

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Tue 7/1

7:15 am-2:23 pm

1 stop6h 08m

Savannah/Hilton Head

Sat 7/5

7:56 pm-11:46 pm

1 stop4h 50m

$199

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Fri 7/4

5:56 am-11:53 am

1 stop4h 57m

Charleston

Tue 7/8

6:23 pm-10:44 pm

1 stop5h 21m

$243

Cedar RapidsSavannah

CID - SAV

CIDSAV

Cedar Rapids

Wed 5/28

6:25 am-2:14 pm

1 stop6h 49m

Savannah/Hilton Head

Tue 6/3

6:59 pm-11:00 pm

1 stop5h 01m

$243

Cedar RapidsCharleston

CID - CHS

CIDCHS

Cedar Rapids

Thu 7/3

7:15 am-12:54 pm

1 stop4h 39m

Charleston

Mon 7/7

6:02 pm-11:46 pm

1 stop6h 44m

$249

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 5/22

7:15 pm-3:37 pm

1 stop19h 22m

Charlotte Douglas

Mon 5/26

6:34 pm-3:36 pm

1 stop22h 02m

$267

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Tue 9/30

2:15 pm-8:48 pm

1 stop5h 33m

Charleston

Tue 10/7

8:00 pm-11:45 pm

1 stop4h 45m

$271

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 6/7

1:15 pm-6:30 pm

2 stops28h 15m

Myrtle Beach Intl

Wed 6/11

6:00 am-1:33 pm

1 stop8h 33m

$275

Des MoinesCharleston

DSM - CHS

DSMCHS

Des Moines

Fri 5/30

10:17 am-6:00 pm

1 stop6h 43m

Charleston

Tue 6/3

4:59 pm-10:30 pm

1 stop6h 31m

$284

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Sat 5/24

6:30 am-11:52 am

1 stop4h 22m

Myrtle Beach Intl

Sat 5/31

6:00 am-10:41 am

1 stop5h 41m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to South Carolina

What is the cheapest month to book a flight from Iowa to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SC?

Find hourly flight availability from Iowa to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

When flying from Iowa to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 30, 2025.
Read through reviews of airlines operating flights from Iowa to South Carolina, such as Alaska Airlines, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,961 reviews

Entertainment

7.1

Comfort

7.9

Food

7.1

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,961 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Entertainment

7.1

Comfort

7.9

Food

7.1

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,295 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Entertainment

7.1

Comfort

7.9

Food

7.1

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,936 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Entertainment

7.1

Comfort

7.9

Food

7.1

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,696 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Entertainment

7.1

Comfort

7.9

Food

7.1

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Allegiant Air
7.3
Good
734 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Entertainment

7.1

Comfort

7.9

Food

7.1

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Iowa to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Iowa to South Carolina one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $136. However, be on the lookout for offers from Frontier and American Airlines, as they are both options that can get you from Iowa to South Carolina for a low price.

  • Can I find deals for flights from Iowa to South Carolina that include hotel bookings?

    Yes. In addition to deals on Iowa to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to South Carolina.

  • Can I find deals for business class flights from Iowa to South Carolina?

    Yes. Cheapflights offers flight deals from Iowa to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Iowa to South Carolina (average of $217). Flying from Iowa to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to South Carolina

Discover the top 4 airlines that operate flights from Iowa to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$383FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$227Average$424FlexibilityNo cancel feeOn-time69%
DeltaCheapest$232Average$350FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$376Average$447FlexibilityNo cancel feeOn-time63%

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