$133+ Cheap flights from Pittsburgh (PIT) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/13. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — BOG
Jun 21 — Jun 281
Round-trip
1 adult, Economy
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Find cheap flights from Pittsburgh to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Pittsburgh to South America
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Cheapest flights from Pittsburgh to South AmericaExplore the most affordable flight options available from Pittsburgh to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
Explore the most affordable flight options available from Pittsburgh to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
This KAYAK deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:35 pm
PIT
- MDE
1 stop29h 30m
Multiple Airlines
Wed 11/410:45 am
MDE
- PIT
1 stop11h 35m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:05 pm
PIT
- CTG
2 stops22h 12m
American Airlines
Mon 7/203:17 pm
CTG
- PIT
2 stops20h 14m
American Airlines
Deal found 5/21![American Airlines logo]()
$332
This KAYAK deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 pm
PIT
- MDE
2 stops26h 05m
Copa Airlines
Wed 11/410:45 am
MDE
- PIT
2 stops12h 37m
Copa Airlines
Deal found 5/20![Copa Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:35 am
PIT
- CTG
1 stop6h 30m
American Airlines
Sat 9/262:05 pm
CTG
- PIT
1 stop7h 28m
American Airlines
Deal found 5/22![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:00 pm
PIT
- CTG
1 stop20h 17m
American Airlines
Tue 8/113:15 pm
CTG
- PIT
1 stop7h 39m
American Airlines
Deal found 5/20![American Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:54 pm
PIT
- CTG
1 stop18h 41m
American Airlines
Sat 8/83:15 pm
CTG
- PIT
2 stops19h 29m
American Airlines
Deal found 5/20![American Airlines logo]()
$369
This Orbitz deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3111:50 am
PIT
- CTG
1 stop26h 19m
LATAM Airlines
Tue 8/112:30 pm
CTG
- PIT
1 stop9h 06m
LATAM Airlines
Deal found 5/20![LATAM Airlines logo]()
$383
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:21 pm
PIT
- MDE
2 stops26h 49m
United Airlines
Tue 6/99:45 am
MDE
- PIT
1 stop13h 14m
United Airlines
Deal found 5/19![United Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:15 am
PIT
- CTG
1 stop7h 20m
American Airlines
Wed 6/103:13 pm
CTG
- PIT
2 stops19h 44m
American Airlines
Deal found 5/20![American Airlines logo]()
$407
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:01 pm
PIT
- CTG
2 stops17h 34m
American Airlines
Tue 7/141:35 pm
CTG
- PIT
2 stops18h 03m
American Airlines
Deal found 5/20![American Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:00 pm
PIT
- MDE
1 stop9h 10m
United Airlines
Sun 8/239:45 am
MDE
- PIT
1 stop13h 14m
United Airlines
Deal found 5/21![United Airlines logo]()
$426
This KAYAK deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:00 pm
PIT
- MDE
1 stop9h 10m
Multiple Airlines
Sun 8/239:45 am
MDE
- PIT
1 stop13h 14m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$431
Best flights from Pittsburgh to South AmericaDiscover carefully curated flight deals from Pittsburgh to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
Discover carefully curated flight deals from Pittsburgh to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:35 am
PIT
- CTG
1 stop6h 30m
American Airlines
Sat 9/262:05 pm
CTG
- PIT
1 stop7h 28m
American Airlines
Deal found 5/19![American Airlines logo]()
$355
This JetBlue deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:00 am
PIT
- CTG
1 stop8h 25m
JetBlue
Thu 11/51:40 pm
CTG
- PIT
1 stop7h 42m
JetBlue
Deal found 5/19![JetBlue logo]()
$355
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:02 pm
PIT
- MDE
1 stop29h 08m
United Airlines
Tue 6/99:45 am
MDE
- PIT
1 stop13h 14m
United Airlines
Deal found 5/19![United Airlines logo]()
$400
This LATAM Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am
PIT
- BOG
2 stops15h 15m
LATAM Airlines
Fri 11/1310:55 am
BOG
- PIT
2 stops23h 43m
LATAM Airlines
Deal found 5/22![LATAM Airlines logo]()
$499
This Air Canada deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:15 pm
PIT
- LIM
2 stops18h 30m
Air Canada
Fri 11/68:00 am
LIM
- PIT
1 stop31h 31m
Air Canada
Deal found 5/21![Air Canada logo]()
$597
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:30 am
PIT
- BOG
1 stop14h 45m
Delta
Mon 7/132:55 pm
BOG
- PIT
1 stop17h 13m
Delta
Deal found 5/17![Delta logo]()
$635
This Copa Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:10 am
PIT
- LIM
2 stops19h 45m
Copa Airlines
Fri 9/182:15 am
LIM
- PIT
2 stops15h 58m
Copa Airlines
Deal found 5/21![Copa Airlines logo]()
$718
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:35 am
PIT
- CTG
1 stop6h 30m
American Airlines
Tue 9/152:05 pm
CTG
- PIT
2 stops21h 32m
American Airlines
Deal found 5/18![American Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:45 pm
PIT
- CTG
2 stops19h 32m
American Airlines
Sat 8/83:15 pm
CTG
- PIT
2 stops19h 29m
American Airlines
Deal found 5/20![American Airlines logo]()
$360
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:00 pm
PIT
- MDE
1 stop9h 10m
United Airlines
Sun 8/239:45 am
MDE
- PIT
1 stop13h 14m
United Airlines
Deal found 5/21![United Airlines logo]()
$426
This JetBlue deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am
PIT
- CTG
1 stop6h 30m
JetBlue
Thu 10/112:35 pm
CTG
- PIT
1 stop7h 48m
JetBlue
Deal found 5/20![JetBlue logo]()
$487
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:02 pm
PIT
- MDE
1 stop29h 08m
United Airlines
Wed 6/109:45 am
MDE
- PIT
2 stops22h 55m
United Airlines
Deal found 5/20![United Airlines logo]()
$444
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:37 pm
PIT
- CTG
2 stops18h 36m
American Airlines
Sat 7/41:35 pm
CTG
- PIT
2 stops19h 45m
American Airlines
Deal found 5/20![American Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:16 pm
PIT
- MDE
2 stops27h 54m
United Airlines
Sun 7/59:45 am
MDE
- PIT
2 stops28h 38m
United Airlines
Deal found 5/21![United Airlines logo]()
$453
This Mytrip deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
PIT
- SCL
2 stops33h 34m
Multiple Airlines
Tue 6/233:20 pm
SCL
- PIT
3 stops25h 47m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$1,129
This BusinessClass deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:16 am
PIT
- GIG
2 stops15h 44m
GOL
Sat 7/46:25 pm
GIG
- PIT
2 stops23h 36m
GOL
Deal found 5/20![GOL logo]()
$1,181
This LATAM Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am
PIT
- BOG
2 stops12h 40m
LATAM Airlines
Tue 11/38:35 am
BOG
- PIT
2 stops15h 44m
LATAM Airlines
Deal found 5/22![LATAM Airlines logo]()
$637
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:40 pm
PIT
- MDE
2 stops26h 30m
United Airlines
Mon 7/139:45 am
MDE
- PIT
2 stops22h 55m
United Airlines
Deal found 5/22![United Airlines logo]()
$496
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
PIT
- UIO
2 stops14h 05m
Delta
Sat 9/1912:59 am
UIO
- PIT
1 stop8h 40m
Delta
Deal found 5/18![Delta logo]()
$662
This Copa Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:36 am
PIT
- LIM
2 stops17h 44m
Copa Airlines
Thu 7/911:00 am
LIM
- PIT
2 stops21h 40m
Copa Airlines
Deal found 5/19![Copa Airlines logo]()
$721
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:16 pm
PIT
- MDE
2 stops27h 54m
United Airlines
Tue 6/239:45 am
MDE
- PIT
1 stop24h 40m
United Airlines
Deal found 5/18![United Airlines logo]()
$497
This LATAM Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:20 pm
PIT
- BOG
2 stops26h 50m
LATAM Airlines
Sat 6/2010:40 am
BOG
- PIT
2 stops12h 50m
LATAM Airlines
Deal found 5/22![LATAM Airlines logo]()
$668
This Delta deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:05 am
PIT
- BOG
2 stops13h 05m
Delta
Sun 8/168:40 am
BOG
- PIT
2 stops23h 25m
Delta
Deal found 5/21![Delta logo]()
$721
This Copa Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:40 pm
PIT
- LIM
2 stops24h 35m
Copa Airlines
Mon 7/272:15 am
LIM
- PIT
2 stops17h 36m
Copa Airlines
Deal found 5/19![Copa Airlines logo]()
$737
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:15 am
PIT
- MDE
1 stop15h 55m
United Airlines
Fri 6/199:45 am
MDE
- PIT
1 stop13h 14m
United Airlines
Deal found 5/19![United Airlines logo]()
$507
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:00 am
PIT
- BOG
2 stops14h 17m
American Airlines
Sun 8/166:30 am
BOG
- PIT
1 stop9h 30m
American Airlines
Deal found 5/19![American Airlines logo]()
$633
This Air Canada deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:15 pm
PIT
- SCL
1 stop17h 00m
Air Canada
Thu 10/297:55 pm
SCL
- PIT
1 stop20h 36m
Air Canada
Deal found 5/18![Air Canada logo]()
$887
This Copa Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:36 am
PIT
- LIM
2 stops28h 49m
Copa Airlines
Thu 7/94:40 pm
LIM
- PIT
2 stops16h 18m
Copa Airlines
Deal found 5/18![Copa Airlines logo]()
$737
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:25 pm
PIT
- EZE
1 stop14h 20m
Delta
Wed 6/177:35 am
EZE
- PIT
2 stops18h 20m
Delta
Deal found 5/19![Delta logo]()
$779
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:01 pm
PIT
- AEP
2 stops18h 39m
Delta
Wed 6/173:45 pm
AEP
- PIT
2 stops20h 00m
Delta
Deal found 5/19![Delta logo]()
$787
Last-minute flights from Pittsburgh to South AmericaDiscover last-minute flight deals from Pittsburgh to South America. Data last updated May 22, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to South America. Data last updated May 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:15 am
PIT
- CTG
1 stop7h 20m
American Airlines
Wed 6/103:13 pm
CTG
- PIT
2 stops19h 44m
American Airlines
Deal found 5/20![American Airlines logo]()
$407
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:15 am
PIT
- CTG
1 stop7h 20m
American Airlines
Tue 6/21:35 pm
CTG
- PIT
2 stops19h 44m
American Airlines
Deal found 5/19![American Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:07 am
PIT
- CTG
2 stops14h 28m
Delta
Tue 6/210:20 am
CTG
- PIT
2 stops13h 25m
Delta
Deal found 5/19![Delta logo]()
$448
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:52 am
PIT
- CTG
2 stops17h 43m
Delta
Wed 6/109:30 am
CTG
- PIT
2 stops14h 25m
Delta
Deal found 5/20![Delta logo]()
$458
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:05 pm
PIT
- MDE
1 stop9h 05m
United Airlines
Sun 5/319:45 am
MDE
- PIT
1 stop13h 14m
United Airlines
Deal found 5/21![United Airlines logo]()
$467
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:21 pm
PIT
- MDE
2 stops26h 49m
United Airlines
Tue 6/99:45 am
MDE
- PIT
1 stop13h 14m
United Airlines
Deal found 5/19![United Airlines logo]()
$397
This KAYAK deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:21 pm
PIT
- MDE
2 stops26h 49m
Multiple Airlines
Tue 6/99:45 am
MDE
- PIT
1 stop13h 14m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$446
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:02 pm
PIT
- MDE
1 stop29h 08m
United Airlines
Wed 6/109:45 am
MDE
- PIT
2 stops22h 55m
United Airlines
Deal found 5/20![United Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:16 pm
PIT
- MDE
2 stops27h 54m
United Airlines
Sun 7/59:45 am
MDE
- PIT
2 stops28h 38m
United Airlines
Deal found 5/20![United Airlines logo]()
$453
This KAYAK deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/124:55 pm
PIT
- CTG
2 stops20h 40m
GOL
Wed 6/173:13 pm
CTG
- PIT
2 stops19h 44m
GOL
Deal found 5/19![GOL logo]()
$455
This LATAM Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:00 am
PIT
- BOG
2 stops16h 10m
LATAM Airlines
Sat 7/411:00 am
BOG
- PIT
2 stops12h 55m
LATAM Airlines
Deal found 5/20![LATAM Airlines logo]()
$486
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:37 pm
PIT
- CTG
2 stops18h 36m
American Airlines
Sat 7/41:35 pm
CTG
- PIT
2 stops19h 45m
American Airlines
Deal found 5/20![American Airlines logo]()
$420
One-way flights from Pittsburgh to South AmericaSearch for one-way flight options from Pittsburgh to South America. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
Search for one-way flight options from Pittsburgh to South America. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:15 am
PIT
- MDE
1 stop15h 55m
United Airlines
Deal found 5/22![United Airlines logo]()
$133
This SmartFares deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
PIT
- CTG
1 stop6h 35m
JetBlue
Deal found 5/20![JetBlue logo]()
$138
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:16 am
PIT
- CTG
2 stops8h 59m
American Airlines
Deal found 5/20![American Airlines logo]()
$154
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:15 am
PIT
- MDE
1 stop15h 55m
United Airlines
Deal found 5/18![United Airlines logo]()
$183
This KAYAK deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:59 pm
PIT
- MDE
2 stops26h 11m
Copa Airlines
Deal found 5/18![Copa Airlines logo]()
$188
This KAYAK deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:02 pm
PIT
- MDE
1 stop29h 08m
Avianca
Deal found 5/18![Avianca logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:00 am
PIT
- MDE
3 stops51h 15m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$206
This KAYAK deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:54 am
PIT
- MDE
2 stops35h 16m
Azul
Deal found 5/19![Azul logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:00 am
PIT
- MDE
2 stops31h 45m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$218
This KAYAK deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:02 pm
PIT
- MDE
1 stop29h 08m
Avianca
Deal found 5/19![Avianca logo]()
$223
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:06 am
PIT
- MDE
2 stops40h 04m
United Airlines
Deal found 5/18![United Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:35 pm
PIT
- CTG
2 stops23h 38m
American Airlines
Deal found 5/20![American Airlines logo]()
$232
Find flight deals from Pittsburgh to South America
Keep the following information in mind while searching for Pittsburgh to South America flight deals. Data was last updated May 22, 2026.
Round-trip from | $324 (KAYAK) |
|---|---|
One-way from | $133 (United Airlines) |
Popular in | December |
Cheapest in | March |
Average price | $673 |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Pittsburgh to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Sun 9/20
6:35 am-12:05 pm
1 stop6h 30m
Cartagena Rafael Nunez
Sat 9/26
2:05 pm-10:33 pm
1 stop7h 28m
$355
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Mon 11/2
6:00 am-2:25 pm
1 stop8h 25m
Cartagena Rafael Nunez
Thu 11/5
1:40 pm-9:22 pm
1 stop7h 42m
$355
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Wed 9/9
6:35 am-12:05 pm
1 stop6h 30m
Cartagena Rafael Nunez
Tue 9/15
2:05 pm-12:37 pm
2 stops21h 32m
$360
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Mon 8/3
7:45 pm-2:17 pm
2 stops19h 32m
Cartagena Rafael Nunez
Sat 8/8
3:15 pm-11:44 am
2 stops19h 29m
$360
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Tue 6/2
5:02 pm-9:10 pm
1 stop29h 08m
Medellín Jose Maria Cordova Intl
Tue 6/9
9:45 am-11:59 pm
1 stop13h 14m
$400
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Sat 6/27
8:37 pm-2:13 pm
2 stops18h 36m
Cartagena Rafael Nunez
Sat 7/4
1:35 pm-10:20 am
2 stops19h 45m
$420
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Thu 8/20
1:00 pm-9:10 pm
1 stop9h 10m
Medellín Jose Maria Cordova Intl
Sun 8/23
9:45 am-11:59 pm
1 stop13h 14m
$426
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Thu 6/4
5:02 pm-9:10 pm
1 stop29h 08m
Medellín Jose Maria Cordova Intl
Wed 6/10
9:45 am-9:40 am
2 stops22h 55m
$444
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Fri 6/5
6:16 pm-9:10 pm
2 stops27h 54m
Medellín Jose Maria Cordova Intl
Sun 7/5
9:45 am-3:23 pm
2 stops28h 38m
$453
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Mon 9/28
6:00 am-11:30 am
1 stop6h 30m
Cartagena Rafael Nunez
Thu 10/1
12:35 pm-9:23 pm
1 stop7h 48m
$487
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Pittsburgh to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Pittsburgh with our price prediction graph.
PIT-MDE
PIT-CTG
PIT-BOG
PIT-LIM
PIT-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to South America
PIT-0SA
PIT-MDE
PIT-CTG
PIT-BOG
PIT-LIM
What is the cheapest month to book a flight from Pittsburgh to South America?
Currently, October is the cheapest month in which you can book a flight from Pittsburgh to South America (average of $240). Flying from Pittsburgh to South America in June is currently the most expensive (average of $355). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Pittsburgh to South America?
The best time to book flights from Pittsburgh to South America is 81 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated May 22, 2026.
Peruse reviews from past customers who have flown with Delta,LATAM Airlines, andJetBlue from Pittsburgh to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Spirit Airlines
Overall
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Pittsburgh to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pittsburgh to South America by cabin class
Find flights from Pittsburgh to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pittsburgh and South America flights
Browse other Pittsburgh and South America flight options. Last updated on May 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Pittsburgh to South America flights
Consider these flights traveling from Pittsburgh to South America.
Top 7 airlines flying from Pittsburgh to South America
Discover the top 7 airlines that operate flights from Pittsburgh to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$240 | Average$421 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$286 | Average$660 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$333 | Average$422 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$355 | Average$917 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$568 | Average$775 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$614 | Average$1,002 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$617 | Average$937 | FlexibilityNo cancel fee | On-time70% |