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$131+ Cheap flights from Ohio to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — BOG
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Ohio to South America

Cheapest flights from Ohio to South America
Explore the most affordable flight options available from Ohio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:26 pmCVG - MDE
1 stop16h 31mMultiple Airlines
Fri 12/262:54 pmMDE - CVG
1 stop8h 56mMultiple Airlines
Deal found 12/11$522
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:29 pmDTW - MDE
2 stops22h 26mMultiple Airlines
Wed 12/3111:50 amMDE - DTW
1 stop9h 42mMultiple Airlines
Deal found 12/10$579
This Mytrip deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:58 pmDTW - MDE
2 stops18h 59mSpirit Airlines
Sun 12/212:25 amMDE - DTW
2 stops22h 54mSpirit Airlines
Deal found 12/10$592
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/158:55 pmCVG - MDE
1 stop14h 00mMultiple Airlines
Wed 12/173:10 pmMDE - CVG
1 stop23h 52mMultiple Airlines
Deal found 12/11$594
This Cheapflightsfares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:00 amPIT - MDE
1 stop17h 28mSpirit Airlines
Fri 1/93:15 pmMDE - PIT
1 stop8h 29mSpirit Airlines
Deal found 12/10$611
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/157:42 pmDTW - MDE
1 stop15h 13mMultiple Airlines
Mon 12/226:35 amMDE - DTW
1 stop9h 53mMultiple Airlines
Deal found 12/10$628
This KAYAK deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/157:42 pmDTW - MDE
1 stop15h 13mSpirit Airlines
Wed 1/72:54 pmMDE - DTW
1 stop22h 58mSpirit Airlines
Deal found 12/11$656
This Mytrip deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:39 pmDTW - MDE
3 stops22h 18mSpirit Airlines
Wed 12/3111:50 amMDE - DTW
2 stops21h 43mSpirit Airlines
Deal found 12/10$669
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:12 pmDTW - MDE
1 stop16h 43mMultiple Airlines
Wed 1/72:54 pmMDE - DTW
2 stops19h 52mMultiple Airlines
Deal found 12/11$671
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:04 pmDTW - MDE
2 stops30h 24mMultiple Airlines
Mon 12/296:35 amMDE - DTW
1 stop11h 00mMultiple Airlines
Deal found 12/10$696
This Expedia deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amDTW - LIM
1 stop16h 35mSpirit Airlines
Tue 12/1611:37 pmLIM - DTW
2 stops20h 15mSpirit Airlines
Deal found 12/9$705
This Expedia deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amDTW - LIM
1 stop16h 35mSpirit Airlines
Thu 12/1111:37 pmLIM - DTW
1 stop10h 31mSpirit Airlines
Deal found 12/9$712

Find flight deals from Ohio to South America

Keep the following information in mind while searching for Ohio to South America flight deals. Data was last updated December 12, 2025.

Round-trip from

$257
(Cheapflightsfares)

One-way from

$131
(Kiwi.com)

Popular in

April

Cheapest in

August

Average price

$639
From Ohio to South America
Search Deals
One-way flight from Ohio to South America
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($126 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Ohio to South America that are best for you.

Fly from

Ohio

Fly to

South America

Route

Depart

Return

Price

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Sat 2/7

5:45 am-2:15 pm

1 stop8h 30m

Medellín Jose Maria Cordova Intl

Tue 2/10

2:50 pm-11:19 pm

1 stop8h 29m

$294

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 2/2

7:00 am-2:55 pm

1 stop7h 55m

Medellín Jose Maria Cordova Intl

Fri 2/6

2:25 pm-10:46 pm

1 stop8h 21m

$297

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Sun 2/1

8:10 pm-10:05 pm

2 stops25h 55m

Medellín Jose Maria Cordova Intl

Sat 2/7

10:45 am-9:33 am

2 stops22h 48m

$308

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 2/2

8:10 pm-10:05 pm

2 stops25h 55m

Medellín Jose Maria Cordova Intl

Fri 2/6

10:45 am-1:10 pm

2 stops26h 25m

$308

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Thu 1/1

8:00 am-1:28 am

1 stop17h 28m

Medellín Jose Maria Cordova Intl

Wed 1/21

3:15 pm-11:44 pm

1 stop8h 29m

$313

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Mon 1/26

5:45 am-2:15 pm

1 stop8h 30m

Medellín Jose Maria Cordova Intl

Mon 2/2

3:15 pm-11:27 pm

1 stop8h 12m

$343

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Fri 1/30

5:45 am-2:15 pm

1 stop8h 30m

Medellín Jose Maria Cordova Intl

Mon 2/2

3:15 pm-11:27 pm

1 stop8h 12m

$349

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Sat 1/17

5:15 am-2:15 pm

2 stops9h 00m

Medellín Jose Maria Cordova Intl

Thu 1/22

2:50 pm-11:41 pm

1 stop8h 51m

$360

DetroitLima

DTW - LIM

DTWLIM

Detroit Metropolitan Wayne County

Sat 1/17

5:05 am-10:35 pm

2 stops17h 30m

Lima J Chavez Intl

Sun 1/25

11:33 pm-10:08 pm

2 stops22h 35m

$361

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Thu 2/19

5:40 am-1:55 pm

1 stop8h 15m

Medellín Jose Maria Cordova Intl

Tue 2/24

3:10 pm-11:32 pm

1 stop8h 22m

$364

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to South America

What is the cheapest month to book a flight from Ohio to South America?

Currently, October is the cheapest month in which you can book a flight from Ohio to South America (average of $129). Flying from Ohio to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SA?

Find hourly flight availability from Ohio to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from Ohio to South America is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 13% on airfare.

What is the cheapest day to fly from Ohio to South America?

Use this chart to determine the cheapest time to fly round-trip from Ohio to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Ohio to South America flight should consider departing on Monday evenings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Ohio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Ohio to South America?

    Airlines like Spirit Airlines, JetBlue, and United Airlines fly from Ohio to South America in about 7h 55m. The time it takes to get you to your destination can typically vary by up to 18h. Ohio and South America are separated by a distance of 2389 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Ohio to South America one-way?

    The cheapest airlines for a one-way flight from Ohio to South America are Spirit Airlines ($115), Copa Airlines ($244), and Delta ($245).

  • Can I find deals for flights from Ohio to South America that include hotel bookings?

    Yes. In addition to deals on Ohio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to South America.

  • Can I find deals for business class flights from Ohio to South America?

    Yes. Cheapflights offers flight deals from Ohio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to South America?

    Currently, October is the cheapest month in which you can book a flight from Ohio to South America (average of $129). Flying from Ohio to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Ohio to South America

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Top 8 airlines flying from Ohio to South America

Discover the top 8 airlines that operate flights from Ohio to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$94Average$177FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$261Average$392FlexibilityNo cancel feeOn-time65%
DeltaCheapest$413Average$885FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$443Average$809FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$462Average$1,068FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$472Average$844FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$536Average$756FlexibilityNo cancel feeOn-time70%
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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