South America

$106+ Cheap flights from Ohio to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — BOG
Aug 5 — Aug 121
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Cheap flight deals from Ohio to South America

Keep the following information in mind while searching for Ohio to South America flight deals. Data was last updated July 31, 2025.

Round-trip from

$282
(Cheapflightsfares)

One-way from

$106
(Mytrip)

Popular in

January

Cheapest in

February

Average price

$1,075
From Ohio to South America
One-way flight from Ohio to South America
Highest demand for flights based on searches. 4% potential increase in price ($42 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($26 potential savings vs. average RT price).
Average for round-trip flights in July 2025

Find flight deals from Ohio to South America

Cheapest flights from Ohio to South America
Explore the most affordable flight options available from Ohio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/115:51 pmDTW - MDE
1 stop7h 37mSpirit Airlines
Thu 9/182:09 pmMDE - DTW
1 stop8h 34mSpirit Airlines
Deal found 7/30$283
This Cheapflightsfares deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/187:51 pmCLE - MDE
1 stop18h 23mSpirit Airlines
Sun 9/211:24 amMDE - CLE
1 stop16h 00mSpirit Airlines
Deal found 7/31$302
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/115:51 pmDTW - MDE
1 stop7h 37mMultiple Airlines
Thu 9/186:05 amMDE - DTW
2 stops16h 38mMultiple Airlines
Deal found 7/30$359
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/910:26 amCLE - MDE
2 stops38h 59mMultiple Airlines
Fri 9/121:24 amMDE - CLE
1 stop13h 26mMultiple Airlines
Deal found 7/31$418
This Avianca Connect deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2711:25 amDTW - LIM
2 stops17h 00mMultiple Airlines
Wed 9/38:25 pmLIM - DTW
2 stops22h 35mMultiple Airlines
Deal found 7/30$480
This FlightHub deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/305:15 amCMH - LIM
1 stop15h 55mSpirit Airlines
Sun 9/79:00 amLIM - CMH
1 stop25h 41mSpirit Airlines
Deal found 7/31$489
This Cheapflightsfares deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:58 amDTW - LIM
1 stop15h 00mSpirit Airlines
Mon 1/1211:59 pmLIM - DTW
2 stops21h 59mSpirit Airlines
Deal found 7/30$503
This SmartFares deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/136:29 pmCLE - MDE
2 stops24h 26mLATAM Airlines
Wed 8/207:02 amMDE - CLE
2 stops16h 38mLATAM Airlines
Deal found 7/30$533
This Copa Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/88:00 pmCLE - MDE
2 stops22h 00mCopa Airlines
Tue 9/1610:46 amMDE - CLE
2 stops21h 53mCopa Airlines
Deal found 7/30$535
This FlightHub deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/227:02 pmCLE - LIM
1 stop26h 08mSpirit Airlines
Sun 8/249:00 amLIM - CLE
1 stop31h 57mSpirit Airlines
Deal found 7/31$543
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/275:15 amCMH - LIM
2 stops32h 10mMultiple Airlines
Sun 9/79:20 amLIM - CMH
1 stop25h 28mMultiple Airlines
Deal found 7/30$546
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/16:00 amDTW - GRU
1 stop15h 25mMultiple Airlines
Sun 9/74:35 amGRU - DTW
2 stops16h 25mMultiple Airlines
Deal found 7/29$563

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Ohio to South America that are best for you.

Fly from

Ohio

Fly to

South America

Route

Depart

Return

Price

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Thu 9/11

5:51 pm-12:28 am

1 stop7h 37m

Medellín Jose Maria Cordova Intl

Thu 9/18

2:09 pm-11:43 pm

1 stop8h 34m

$283

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Thu 9/18

7:51 pm-1:14 pm

1 stop18h 23m

Medellín Jose Maria Cordova Intl

Sun 9/21

1:24 am-6:24 pm

1 stop16h 00m

$302

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Thu 9/11

5:51 pm-12:28 am

1 stop7h 37m

Medellín Jose Maria Cordova Intl

Thu 9/18

6:05 am-11:43 pm

2 stops16h 38m

$359

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Tue 1/13

6:00 am-8:00 pm

2 stops14h 00m

Medellín Jose Maria Cordova Intl

Wed 3/11

10:00 pm-6:45 pm

2 stops19h 45m

$406

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Tue 9/9

10:26 am-12:25 am

2 stops38h 59m

Medellín Jose Maria Cordova Intl

Fri 9/12

1:24 am-3:50 pm

1 stop13h 26m

$418

DetroitLima

DTW - LIM

DTWLIM

Detroit Metropolitan Wayne County

Wed 8/27

11:25 am-3:25 am

2 stops17h 00m

Lima J Chavez Intl

Wed 9/3

8:25 pm-8:00 pm

2 stops22h 35m

$480

ColumbusLima

CMH - LIM

CMHLIM

Columbus

Sat 8/30

5:15 am-8:10 pm

1 stop15h 55m

Lima J Chavez Intl

Sun 9/7

9:00 am-11:41 am

1 stop25h 41m

$489

DetroitLima

DTW - LIM

DTWLIM

Detroit Metropolitan Wayne County

Mon 12/22

6:11 am-10:58 pm

1 stop16h 47m

Lima J Chavez Intl

Mon 1/12

11:59 pm-9:58 pm

2 stops21h 59m

$503

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Mon 9/8

8:00 pm-5:00 pm

2 stops22h 00m

Medellín Jose Maria Cordova Intl

Tue 9/16

10:46 am-9:39 am

2 stops21h 53m

$535

ClevelandLima

CLE - LIM

CLELIM

Cleveland Hopkins Intl

Fri 8/22

7:02 pm-8:10 pm

1 stop26h 08m

Lima J Chavez Intl

Sun 8/24

9:00 am-5:57 pm

1 stop31h 57m

$543

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to South America

What is the cheapest month to book a flight from Ohio to South America?

Currently, May is the cheapest month in which you can book a flight from Ohio to South America (average of $359). Flying from Ohio to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SA?

Find hourly flight availability from Ohio to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from Ohio to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 31, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and Copa Airlines from Ohio to South America by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Ohio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from Ohio to South America one-way?

    The cheapest airlines for a one-way flight from Ohio to South America are Spirit Airlines ($106), LATAM Airlines ($246), and American Airlines ($359).

  • Can I find deals for flights from Ohio to South America that include hotel bookings?

    Yes. In addition to deals on Ohio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to South America.

  • Can I find deals for business class flights from Ohio to South America?

    Yes. Cheapflights offers flight deals from Ohio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to South America?

    Currently, May is the cheapest month in which you can book a flight from Ohio to South America (average of $359). Flying from Ohio to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Ohio to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Ohio to South America

Discover the top 7 airlines that operate flights from Ohio to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$239Average$865FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$242Average$424FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$370Average$838FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$401Average$990FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$403Average$877FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$659Average$719FlexibilityNo cancel feeOn-time70%
Air CanadaCheapest$680Average$891FlexibilityNo cancel feeOn-time67%

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