South America

$114+ Cheap flights from Ohio to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — BOG
May 5 — May 121
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Cheap flight deals from Ohio to South America

Keep the following information in mind while searching for Ohio to South America flight deals. Data was last updated April 30, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$305
(FlightHub)

One-way from

$114
(FlightHub)

Popular in

December

Cheapest in

February

Average price

$873
Provider with most accurate pricing for Cleveland Hopkins Intl-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Sao Paulo (SAO) flights.
From Ohio to South America
One-way flight from Ohio to South America
Highest demand for flights based on searches. 16% potential increase in price ($206 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($22 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from Ohio to South America

Cheapest flights from Ohio to South America
Explore the most affordable flight options available from Ohio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This FlightHub deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/148:20 pmDTW - CTG
1 stop16h 50mSpirit Airlines
Thu 6/191:15 pmCTG - DTW
1 stop9h 30mSpirit Airlines
Deal found 4/29$305
This Cheapflightsfares deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/68:11 pmCMH - BOG
1 stop17h 54mSpirit Airlines
Sun 6/82:07 pmBOG - CMH
1 stop17h 43mSpirit Airlines
Deal found 4/28$322
This Cheapflightsfares deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/198:53 pmCMH - MDE
1 stop17h 19mSpirit Airlines
Mon 6/232:13 pmMDE - CMH
1 stop17h 46mSpirit Airlines
Deal found 4/29$332
This Cheapflightsfares deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/155:25 amPIT - BOG
1 stop7h 32mSpirit Airlines
Wed 10/152:03 pmBOG - PIT
1 stop9h 01mSpirit Airlines
Deal found 4/29$345
This Cheapflightsfares deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/158:29 pmDTW - BOG
1 stop16h 28mSpirit Airlines
Mon 10/612:52 pmBOG - DTW
1 stop18h 15mSpirit Airlines
Deal found 4/28$360
This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/275:10 amDTW - MDE
1 stop8h 48mSpirit Airlines
Tue 6/31:53 pmMDE - DTW
1 stop28h 54mSpirit Airlines
Deal found 4/28$360
This Cheapflightsfares deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/185:54 amPIT - MDE
1 stop8h 04mSpirit Airlines
Sat 5/242:13 pmMDE - PIT
1 stop8h 06mSpirit Airlines
Deal found 4/29$378
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/276:00 amDTW - MDE
2 stops13h 54mMultiple Airlines
Tue 6/37:38 amMDE - DTW
2 stops12h 53mMultiple Airlines
Deal found 4/28$399
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/127:10 pmCLE - MDE
2 stops26h 37mMultiple Airlines
Thu 5/229:07 amMDE - CLE
2 stops32h 08mMultiple Airlines
Deal found 4/28$400
This Avianca Connect deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/46:00 amDTW - CTG
2 stops16h 25mMultiple Airlines
Wed 6/115:43 amCTG - DTW
2 stops14h 48mMultiple Airlines
Deal found 4/28$406
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/75:25 amCMH - BOG
2 stops32h 40mMultiple Airlines
Wed 6/115:00 amBOG - CMH
2 stops26h 59mMultiple Airlines
Deal found 4/28$406
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/198:11 pmCMH - MDE
2 stops25h 36mMultiple Airlines
Sun 6/152:10 pmMDE - CMH
1 stop17h 49mMultiple Airlines
Deal found 4/28$413

Cheapflights Fare Finder

Customize your flight search to find flights from Ohio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Ohio to South America that are best for you.

Fly from

Ohio

Fly to

South America

Route

Depart

Return

Price

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Sat 6/14

8:20 pm-12:10 pm

1 stop16h 50m

Cartagena Rafael Nunez

Thu 6/19

1:15 pm-11:45 pm

1 stop9h 30m

$305

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

Fri 6/6

8:11 pm-1:05 pm

1 stop17h 54m

Bogotá El Dorado

Sun 6/8

2:07 pm-8:50 am

1 stop17h 43m

$322

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

Thu 6/19

8:53 pm-1:12 pm

1 stop17h 19m

Medellín Jose Maria Cordova Intl

Mon 6/23

2:13 pm-8:59 am

1 stop17h 46m

$332

PittsburghBogotá

PIT - BOG

PITBOG

Pittsburgh

Wed 10/15

5:25 am-11:57 am

1 stop7h 32m

Bogotá El Dorado

Wed 10/15

2:03 pm-12:04 am

1 stop9h 01m

$345

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Mon 9/15

8:29 pm-11:57 am

1 stop16h 28m

Bogotá El Dorado

Mon 10/6

12:52 pm-8:07 am

1 stop18h 15m

$360

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Tue 5/27

5:10 am-12:58 pm

1 stop8h 48m

Medellín Jose Maria Cordova Intl

Tue 6/3

1:53 pm-7:47 pm

1 stop28h 54m

$360

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Sun 5/18

5:54 am-12:58 pm

1 stop8h 04m

Medellín Jose Maria Cordova Intl

Sat 5/24

2:13 pm-11:19 pm

1 stop8h 06m

$378

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Tue 5/27

6:00 am-6:54 pm

2 stops13h 54m

Medellín Jose Maria Cordova Intl

Tue 6/3

7:38 am-9:31 pm

2 stops12h 53m

$399

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Mon 5/12

7:10 pm-8:47 pm

2 stops26h 37m

Medellín Jose Maria Cordova Intl

Thu 5/22

9:07 am-6:15 pm

2 stops32h 08m

$400

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Wed 6/4

6:00 am-9:25 pm

2 stops16h 25m

Cartagena Rafael Nunez

Wed 6/11

5:43 am-9:31 pm

2 stops14h 48m

$406

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to South America

What is the cheapest month to book a flight from Ohio to South America?

Currently, May is the cheapest month in which you can book a flight from Ohio to South America (average of $359). Flying from Ohio to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SA?

Find hourly flight availability from Ohio to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

When flying from Ohio to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 30, 2025.
8.0
Very good

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good
8.0
Very good

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Ohio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from Ohio to South America one-way?

    The cheapest airlines for a one-way flight from Ohio to South America are Spirit Airlines ($114), Copa Airlines ($239), and American Airlines ($244).

  • Can I find deals for flights from Ohio to South America that include hotel bookings?

    Yes. In addition to deals on Ohio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to South America.

  • Can I find deals for business class flights from Ohio to South America?

    Yes. Cheapflights offers flight deals from Ohio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to South America?

    Currently, May is the cheapest month in which you can book a flight from Ohio to South America (average of $359). Flying from Ohio to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Ohio to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Ohio to South America

Discover the top 7 airlines that operate flights from Ohio to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$277Average$437FlexibilityNo cancel feeOn-time65%
DeltaCheapest$299Average$905FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$370Average$840FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$401Average$1,006FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$445Average$916FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$659Average$719FlexibilityNo cancel feeOn-time70%
Air CanadaCheapest$744Average$1,014FlexibilityNo cancel feeOn-time67%

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