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$107+ Cheap flights from Ohio to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — BOG
nov. 28 — dic. 51
vie. 11/28
vie. 12/5
1 adult, Economy
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Find flight deals from Ohio to South America

Cheapest flights from Ohio to South America
Explore the most affordable flight options available from Ohio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 29, 2025.

This Orbitz deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/279:01 pmDTW - CTG
2 stops16h 24mSpirit Airlines
jue. 12/42:15 pmCTG - DTW
1 stop10h 04mSpirit Airlines
Deal found 10/28$291
This CheapOair deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/158:05 pmDTW - CTG
1 stop17h 10mSpirit Airlines
sáb. 11/222:30 pmCTG - DTW
1 stop9h 24mSpirit Airlines
Deal found 10/27$293
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/272:52 pmDTW - CTG
1 stop22h 33mMultiple Airlines
jue. 12/42:15 pmCTG - DTW
1 stop10h 04mMultiple Airlines
Deal found 10/28$323
This Orbitz deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/148:05 pmDTW - BOG
1 stop18h 05mSpirit Airlines
lun. 12/13:17 pmBOG - DTW
2 stops26h 16mSpirit Airlines
Deal found 10/28$325
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/118:05 pmDTW - BOG
1 stop18h 05mSpirit Airlines
sáb. 11/223:17 pmBOG - DTW
1 stop8h 37mSpirit Airlines
Deal found 10/27$326
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/118:05 pmDTW - BOG
1 stop18h 05mSpirit Airlines
jue. 11/203:17 pmBOG - DTW
1 stop8h 37mSpirit Airlines
Deal found 10/27$328
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/156:29 pmDTW - CTG
2 stops18h 46mMultiple Airlines
sáb. 11/222:30 pmCTG - DTW
1 stop9h 24mMultiple Airlines
Deal found 10/26$329
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/118:05 pmDTW - BOG
1 stop18h 05mMultiple Airlines
jue. 11/203:17 pmBOG - DTW
2 stops16h 49mMultiple Airlines
Deal found 10/27$331
This KAYAK deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/19:53 pmDTW - BOG
1 stop15h 07mSpirit Airlines
lun. 12/83:05 pmBOG - DTW
1 stop9h 14mSpirit Airlines
Deal found 10/27$339
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/107:17 pmDTW - BOG
2 stops18h 53mSpirit Airlines
jue. 11/201:55 pmBOG - DTW
1 stop9h 51mSpirit Airlines
Deal found 10/27$340
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/157:17 pmDTW - BOG
2 stops18h 53mSpirit Airlines
mar. 12/21:55 pmBOG - DTW
1 stop9h 51mSpirit Airlines
Deal found 10/28$345
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/107:17 pmDTW - BOG
2 stops18h 53mSpirit Airlines
vie. 11/213:17 pmBOG - DTW
1 stop30h 41mSpirit Airlines
Deal found 10/27$346

Cheap flight deals from Ohio to South America

Keep the following information in mind while searching for Ohio to South America flight deals. Data was last updated octubre 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$291
(Orbitz)

One-way from

$107
(Cheapflightsfares)

Popular in

January

Cheapest in

February
Provider with most accurate pricing for Cleveland Hopkins Intl-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Sao Paulo (SAO) flights.
Search Deals
From Ohio to South America
Search Deals
One-way flight from Ohio to South America
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($116 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($52 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
Use the filters below to find and compare flights from Ohio to South America that are best for you.

Fly from

Ohio

Fly to

South America

Route

Depart

Return

Price

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

sáb. 1/24

11:10 am-1:08 pm

2 stops25h 58m

Cartagena Rafael Nunez

sáb. 2/7

2:16 pm-12:25 am

1 stop10h 09m

$322

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

vie. 11/14

8:05 pm-2:10 pm

1 stop18h 05m

Bogotá El Dorado

lun. 12/1

3:17 pm-5:33 pm

2 stops26h 16m

$325

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

sáb. 11/15

6:29 pm-1:15 pm

2 stops18h 46m

Cartagena Rafael Nunez

sáb. 11/22

2:30 pm-11:54 pm

1 stop9h 24m

$329

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

jue. 1/22

6:11 am-1:08 pm

1 stop6h 57m

Cartagena Rafael Nunez

lun. 1/26

2:16 pm-12:25 am

1 stop10h 09m

$333

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

sáb. 1/3

6:00 am-1:57 pm

1 stop7h 57m

Medellín Jose Maria Cordova Intl

mar. 2/10

3:11 pm-12:25 am

1 stop9h 14m

$342

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

dom. 12/14

7:42 pm-1:57 pm

1 stop18h 15m

Medellín Jose Maria Cordova Intl

mar. 12/16

2:05 am-10:08 am

1 stop8h 03m

$360

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

sáb. 11/15

8:05 pm-2:10 pm

1 stop18h 05m

Bogotá El Dorado

mar. 12/2

1:55 pm-11:46 pm

1 stop9h 51m

$361

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

lun. 11/10

5:25 am-9:40 pm

1 stop16h 15m

Medellín Jose Maria Cordova Intl

mar. 11/18

1:00 pm-11:10 pm

1 stop10h 10m

$364

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

vie. 11/21

9:53 pm-2:01 pm

1 stop16h 08m

Medellín Jose Maria Cordova Intl

lun. 12/1

2:57 pm-9:58 am

1 stop19h 01m

$372

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

jue. 11/13

5:25 am-2:03 pm

1 stop8h 38m

Medellín Jose Maria Cordova Intl

vie. 11/21

3:14 pm-11:51 pm

1 stop8h 37m

$378

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to South America

What is the cheapest month to book a flight from Ohio to South America?

Currently, October is the cheapest month in which you can book a flight from Ohio to South America (average of $129). Flying from Ohio to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SA?

Find hourly flight availability from Ohio to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 29, 2025.

One of the essential ways to save on airfare from Ohio to South America is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 15% on airfare.

What is the cheapest day to fly from Ohio to South America?

Use this chart to determine the cheapest time to fly round-trip from Ohio to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Ohio to South America flight should consider departing on Tuesday evenings when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Ohio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Ohio to South America?

    Airlines like Spirit Airlines, Delta, and United Airlines fly from Ohio to South America in about 12h 15m. The time it takes to get you to your destination can typically vary by up to 13h 43m. Ohio and South America are separated by a distance of 3559 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Ohio to South America that include hotel bookings?

    Yes. In addition to deals on Ohio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to South America.

  • Can I find deals for business class flights from Ohio to South America?

    Yes. Cheapflights offers flight deals from Ohio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to South America?

    Currently, October is the cheapest month in which you can book a flight from Ohio to South America (average of $129). Flying from Ohio to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Ohio to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Ohio to South America

Discover the top 7 airlines that operate flights from Ohio to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$261Average$437FlexibilityNo cancel feeOn-time65%
DeltaCheapest$384Average$861FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$442Average$822FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$462Average$1,023FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$469Average$826FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$659Average$706FlexibilityNo cancel feeOn-time70%
Air CanadaCheapest$744Average$956FlexibilityNo cancel feeOn-time67%

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