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$119+ Cheap flights from Ohio to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — BOG
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Ohio to South America

Keep the following information in mind while searching for Ohio to South America flight deals. Data was last updated September 11, 2025.

Round-trip from

$260
(Kiwi.com)

One-way from

$119
(Cheapflightsfares)

Popular in

September

Cheapest in

February

Average price

$1,437
From Ohio to South America
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One-way flight from Ohio to South America
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Highest demand for flights based on searches. 7% potential increase in price ($77 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($42 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Ohio to South America

Cheapest flights from Ohio to South America
Explore the most affordable flight options available from Ohio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/196:00 amCVG - MDE
1 stop19h 21mMultiple Airlines
Fri 10/241:16 amMDE - CVG
1 stop9h 40mMultiple Airlines
Deal found 9/9$257
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:29 pmDTW - MDE
1 stop6h 52mSpirit Airlines
Fri 10/311:16 amMDE - DTW
1 stop7h 38mSpirit Airlines
Deal found 9/10$286
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/318:27 pmCVG - MDE
1 stop28h 54mMultiple Airlines
Mon 11/33:22 pmMDE - CVG
1 stop8h 55mMultiple Airlines
Deal found 9/9$290
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:43 amDTW - MDE
1 stop18h 38mSpirit Airlines
Sun 10/261:16 amMDE - DTW
1 stop7h 38mSpirit Airlines
Deal found 9/11$331
This KAYAK deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:29 pmDTW - MDE
1 stop6h 52mSpirit Airlines
Sat 10/251:16 amMDE - DTW
1 stop7h 38mSpirit Airlines
Deal found 9/11$333
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:29 pmDTW - MDE
1 stop30h 52mMultiple Airlines
Fri 10/311:16 amMDE - DTW
2 stops31h 00mMultiple Airlines
Deal found 9/10$335
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:22 pmDTW - MDE
2 stops29h 59mMultiple Airlines
Tue 10/211:16 amMDE - DTW
1 stop21h 14mMultiple Airlines
Deal found 9/11$343
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:29 pmDTW - MDE
1 stop6h 52mSpirit Airlines
Mon 10/201:16 amMDE - DTW
1 stop7h 38mSpirit Airlines
Deal found 9/11$352
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:29 pmDTW - MDE
1 stop30h 52mSpirit Airlines
Tue 10/211:16 amMDE - DTW
1 stop21h 14mSpirit Airlines
Deal found 9/11$355
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/217:30 amCVG - MDE
1 stop30h 44mMultiple Airlines
Thu 9/252:09 pmMDE - CVG
1 stop23h 39mMultiple Airlines
Deal found 9/10$379
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:05 pmCVG - MDE
2 stops31h 16mMultiple Airlines
Mon 11/33:22 pmMDE - CVG
1 stop8h 55mMultiple Airlines
Deal found 9/9$382
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:00 amCVG - MDE
1 stop19h 21mMultiple Airlines
Sat 10/181:16 amMDE - CVG
1 stop21h 08mMultiple Airlines
Deal found 9/10$385

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Ohio to South America that are best for you.

Fly from

Ohio

Fly to

South America

Route

Depart

Return

Price

CincinnatiMedellín

CVG - MDE

CVGMDE

Cincinnati Cinci./N. Kentucky

Sun 10/19

6:00 am-12:21 am

1 stop19h 21m

Medellín Jose Maria Cordova Intl

Fri 10/24

1:16 am-11:56 am

1 stop9h 40m

$257

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Sat 10/25

6:29 pm-12:21 am

1 stop6h 52m

Medellín Jose Maria Cordova Intl

Sat 11/1

2:22 pm-11:30 pm

1 stop8h 08m

$326

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Fri 10/17

7:22 pm-12:21 am

2 stops29h 59m

Medellín Jose Maria Cordova Intl

Tue 10/21

1:16 am-11:30 pm

1 stop21h 14m

$343

CincinnatiMedellín

CVG - MDE

CVGMDE

Cincinnati Cinci./N. Kentucky

Fri 10/31

6:09 pm-11:24 pm

2 stops30h 15m

Medellín Jose Maria Cordova Intl

Mon 11/3

3:22 pm-12:17 am

1 stop8h 55m

$348

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Thu 10/16

6:29 pm-12:21 am

1 stop6h 52m

Medellín Jose Maria Cordova Intl

Mon 10/20

1:16 am-9:54 am

1 stop7h 38m

$352

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Thu 10/16

6:29 pm-12:21 am

1 stop30h 52m

Medellín Jose Maria Cordova Intl

Tue 10/21

1:16 am-5:50 pm

2 stops15h 34m

$352

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Thu 10/23

11:46 am-12:21 am

2 stops13h 35m

Medellín Jose Maria Cordova Intl

Sat 10/25

1:16 am-9:54 am

1 stop7h 38m

$355

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Thu 10/16

6:29 pm-12:21 am

1 stop6h 52m

Medellín Jose Maria Cordova Intl

Sun 10/19

1:16 am-9:54 am

1 stop7h 38m

$375

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Fri 10/17

6:29 pm-12:21 am

1 stop6h 52m

Medellín Jose Maria Cordova Intl

Tue 10/21

1:16 am-9:54 am

1 stop7h 38m

$375

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Fri 10/24

6:29 pm-12:21 am

1 stop6h 52m

Medellín Jose Maria Cordova Intl

Mon 10/27

1:59 pm-9:54 am

2 stops18h 55m

$392

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to South America

What is the cheapest month to book a flight from Ohio to South America?

Currently, May is the cheapest month in which you can book a flight from Ohio to South America (average of $359). Flying from Ohio to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SA?

Find hourly flight availability from Ohio to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Ohio to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Ohio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Ohio to South America?

    Airlines like Spirit Airlines, LATAM Airlines, and Delta fly from Ohio to South America in about 6h 52m. The time it takes to get you to your destination can typically vary by up to 8h 42m. Ohio and South America are separated by a distance of 2537 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Ohio to South America that include hotel bookings?

    Yes. In addition to deals on Ohio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to South America.

  • Can I find deals for business class flights from Ohio to South America?

    Yes. Cheapflights offers flight deals from Ohio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to South America?

    Currently, May is the cheapest month in which you can book a flight from Ohio to South America (average of $359). Flying from Ohio to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Ohio to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Ohio to South America

Discover the top 7 airlines that operate flights from Ohio to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$239Average$880FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$242Average$429FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$370Average$857FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$423Average$861FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$462Average$1,029FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$659Average$719FlexibilityNo cancel feeOn-time70%
Air CanadaCheapest$680Average$891FlexibilityNo cancel feeOn-time67%

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