$385+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Santa Cruz de la Sierra (VVI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/28. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — VVI
Sep 16 — Sep 231
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Santa Cruz de la Sierra with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Santa Cruz de la Sierra
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Last-minute
One-way
Cheapest flights from Detroit to Santa Cruz de la SierraExplore the most affordable flight options available from Detroit to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
Explore the most affordable flight options available from Detroit to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
This KAYAK deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:15 am -
2 stops16h 23m
Thu 10/811:47 am -
2 stops34h 43m
Deal found 8/13![Copa Airlines logo]()
$967
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:26 am -
2 stops19h 11m
Tue 11/1711:49 am -
2 stops23h 29m
Deal found 8/13![United Airlines logo]()
$988
This Copa Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:25 am -
2 stops17h 19m
Fri 9/181:12 am -
2 stops32h 20m
Deal found 8/13![Copa Airlines logo]()
$1,019
This Copa Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:15 am -
2 stops37h 29m
Fri 9/111:12 am -
2 stops19h 13m
Deal found 8/12![Copa Airlines logo]()
$1,046
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:34 am -
2 stops39h 10m
Sat 9/1911:47 am -
3 stops47h 40m
Deal found 8/13![United Airlines logo]()
$1,058
This Expedia deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:00 am -
2 stops19h 30m
Sat 9/193:35 am -
2 stops35h 17m
Deal found 8/16![Multiple Airlines logo]()
$1,176
This United deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:00 pm -
2 stops57h 30m
Sat 9/1211:47 am -
3 stops47h 40m
Deal found 8/12![Multiple Airlines logo]()
$1,268
This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:55 pm -
3 stops35h 35m
Fri 9/183:35 am -
3 stops34h 37m
Deal found 8/13![Multiple Airlines logo]()
$1,438
This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:00 pm -
2 stops36h 30m
Thu 10/81:40 pm -
3 stops28h 32m
Deal found 8/13![Multiple Airlines logo]()
$1,876
Best flights from Detroit to Santa Cruz de la SierraDiscover carefully curated flight deals from Detroit to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
Discover carefully curated flight deals from Detroit to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
This KAYAK deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:15 am -
2 stops16h 23m
Thu 10/811:47 am -
2 stops34h 43m
Deal found 8/13![Copa Airlines logo]()
$967
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:00 am -
2 stops19h 37m
Tue 11/1711:49 am -
2 stops37h 08m
Deal found 8/12![United Airlines logo]()
$988
This United deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:00 pm -
2 stops57h 30m
Sat 9/1211:47 am -
3 stops47h 40m
Deal found 8/12![Multiple Airlines logo]()
$1,268
This Copa Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:25 am -
2 stops17h 19m
Fri 9/181:12 am -
2 stops32h 20m
Deal found 8/13![Copa Airlines logo]()
$1,019
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:34 am -
2 stops39h 10m
Sat 9/1911:47 am -
3 stops47h 40m
Deal found 8/13![United Airlines logo]()
$1,058
This Copa Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:15 am -
2 stops37h 29m
Fri 9/111:12 am -
2 stops19h 13m
Deal found 8/12![Copa Airlines logo]()
$1,046
This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:55 pm -
3 stops35h 35m
Fri 9/183:35 am -
3 stops34h 37m
Deal found 8/13![Multiple Airlines logo]()
$1,438
This Mytrip deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:55 pm -
3 stops35h 35m
Sat 9/193:35 am -
2 stops34h 37m
Deal found 8/16![Multiple Airlines logo]()
$1,656
Last-minute flights from Detroit to Santa Cruz de la SierraDiscover last-minute flight deals from Detroit to Santa Cruz de la Sierra. Data last updated August 17, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Santa Cruz de la Sierra. Data last updated August 17, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:15 am -
2 stops37h 29m
Fri 9/111:12 am -
2 stops19h 13m
Deal found 8/12![Copa Airlines logo]()
$1,046
This United deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:00 pm -
2 stops57h 30m
Sat 9/1211:47 am -
3 stops47h 40m
Deal found 8/12![Multiple Airlines logo]()
$1,268
This Copa Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:25 am -
2 stops17h 19m
Fri 9/181:12 am -
2 stops32h 20m
Deal found 8/13![Copa Airlines logo]()
$1,019
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:34 am -
2 stops39h 10m
Sat 9/1911:47 am -
3 stops47h 40m
Deal found 8/13![United Airlines logo]()
$1,058
This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:55 pm -
3 stops35h 35m
Fri 9/183:35 am -
3 stops34h 37m
Deal found 8/13![Multiple Airlines logo]()
$1,438
This Expedia deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:00 am -
2 stops19h 30m
Sat 9/193:35 am -
2 stops35h 17m
Deal found 8/16![Multiple Airlines logo]()
$1,176
One-way flights from Detroit to Santa Cruz de la SierraSearch for one-way flight options from Detroit to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
Search for one-way flight options from Detroit to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:21 pm -
3 stops53h 19m
Deal found 8/14![Multiple Airlines logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/164:23 pm -
3 stops54h 21m
Deal found 8/14![Multiple Airlines logo]()
$426
Find flight deals from Detroit to Santa Cruz de la Sierra
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 17, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $967 (KAYAK) |
One-way from | $385 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitSanta Cruz de la Sierra
DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl
DTWVVI
Detroit Metropolitan Wayne County
Mon 10/5
11:15 am-3:38 am
2 stops16h 23m
Santa Cruz de la Sierra Viru Viru Intl
Thu 10/8
11:47 am-10:30 pm
2 stops34h 43m
$967
DetroitSanta Cruz de la Sierra
DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl
DTWVVI
Detroit Metropolitan Wayne County
Fri 11/13
7:00 am-3:37 am
2 stops19h 37m
Santa Cruz de la Sierra Viru Viru Intl
Tue 11/17
11:49 am-11:57 pm
2 stops37h 08m
$988
Quickest round-trip
DetroitSanta Cruz de la Sierra
DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl
DTWVVI
Detroit Metropolitan Wayne County
Sat 9/12
5:25 am-10:44 pm
2 stops17h 19m
Santa Cruz de la Sierra Viru Viru Intl
Fri 9/18
1:12 am-9:32 am
2 stops32h 20m
$1,019
DetroitSanta Cruz de la Sierra
DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl
DTWVVI
Detroit Metropolitan Wayne County
Sat 9/5
9:15 am-10:44 pm
2 stops37h 29m
Santa Cruz de la Sierra Viru Viru Intl
Fri 9/11
1:12 am-8:25 pm
2 stops19h 13m
$1,046
DetroitSanta Cruz de la Sierra
DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl
DTWVVI
Detroit Metropolitan Wayne County
Sat 9/12
7:34 am-10:44 pm
2 stops39h 10m
Santa Cruz de la Sierra Viru Viru Intl
Sat 9/19
11:47 am-11:27 am
3 stops47h 40m
$1,058
DetroitSanta Cruz de la Sierra
DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl
DTWVVI
Detroit Metropolitan Wayne County
Sat 9/5
5:00 pm-2:30 am
2 stops57h 30m
Santa Cruz de la Sierra Viru Viru Intl
Sat 9/12
11:47 am-11:27 am
3 stops47h 40m
$1,268
DetroitSanta Cruz de la Sierra
DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl
DTWVVI
Detroit Metropolitan Wayne County
Sat 9/12
2:55 pm-2:30 am
3 stops35h 35m
Santa Cruz de la Sierra Viru Viru Intl
Fri 9/18
3:35 am-2:12 pm
3 stops34h 37m
$1,438
DetroitSanta Cruz de la Sierra
DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl
DTWVVI
Detroit Metropolitan Wayne County
Sun 9/13
2:55 pm-2:30 am
3 stops35h 35m
Santa Cruz de la Sierra Viru Viru Intl
Sat 9/19
3:35 am-2:12 pm
2 stops34h 37m
$1,656
Cheapest one-way
Quickest one-way
DetroitSanta Cruz de la Sierra
DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl
DTWVVI
Detroit Metropolitan Wayne County
Fri 8/28
5:21 pm-10:40 pm
3 stops53h 19m
$385
DetroitSanta Cruz de la Sierra
DTW Detroit Metropolitan Wayne County - VVI Santa Cruz de la Sierra Viru Viru Intl
DTWVVI
Detroit Metropolitan Wayne County
Wed 9/16
4:23 pm-10:44 pm
3 stops54h 21m
$426
Sorted by cheapest first
Compare providers for flights from Detroit to Santa Cruz de la Sierra
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Santa Cruz de la Sierra in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Santa Cruz de la Sierra flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Detroit Metropolitan Wayne County Airport-Santa Cruz de la Sierra flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Santa Cruz de la Sierra flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Santa Cruz de la Sierra
Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Detroit with our price prediction graph.
DTW-VVI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Detroit to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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