$92+ Cheap flights from Chicago (CHI) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — BOG
May 18 — May 251
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Chicago to South America
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Cheapest flights from Chicago to South AmericaExplore the most affordable flight options available from Chicago to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.
Explore the most affordable flight options available from Chicago to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.
This CheapOair deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:05 am
ORD
- CTG
1 stop7h 21m
Spirit Airlines
Fri 5/151:31 pm
CTG
- ORD
1 stop9h 44m
Spirit Airlines
Deal found 4/14![Spirit Airlines logo]()
$301
This Orbitz deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:28 am
ORD
- CTG
2 stops24h 58m
Spirit Airlines
Fri 5/81:31 pm
CTG
- ORD
1 stop9h 44m
Spirit Airlines
Deal found 4/17![Spirit Airlines logo]()
$305
This Copa Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:06 am
ORD
- BOG
1 stop9h 20m
Copa Airlines
Wed 5/67:00 am
BOG
- ORD
1 stop18h 15m
Copa Airlines
Deal found 4/16![Copa Airlines logo]()
$305
This Expedia deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:05 am
ORD
- CTG
1 stop7h 01m
Spirit Airlines
Thu 4/301:11 pm
CTG
- ORD
1 stop11h 13m
Spirit Airlines
Deal found 4/15![Spirit Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:05 am
ORD
- CTG
1 stop7h 21m
Multiple Airlines
Fri 5/291:31 pm
CTG
- ORD
1 stop23h 06m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$313
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:00 am
ORD
- BOG
1 stop17h 38m
American Airlines
Thu 5/2112:50 pm
BOG
- ORD
1 stop11h 34m
American Airlines
Deal found 4/16![American Airlines logo]()
$321
This Mytrip deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:05 am
ORD
- MDE
2 stops18h 35m
Multiple Airlines
Wed 5/205:00 am
MDE
- ORD
2 stops18h 15m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$322
This KAYAK deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:05 am
ORD
- CTG
1 stop7h 21m
Spirit Airlines
Wed 5/61:31 pm
CTG
- ORD
1 stop18h 51m
Spirit Airlines
Deal found 4/15![Spirit Airlines logo]()
$324
This Cheapflightsfares deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:15 pm
ORD
- CTG
1 stop16h 51m
Spirit Airlines
Wed 5/61:31 pm
CTG
- ORD
2 stops22h 52m
Spirit Airlines
Deal found 4/17![Spirit Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:00 am
ORD
- BOG
1 stop17h 30m
American Airlines
Tue 4/216:30 am
BOG
- ORD
2 stops12h 52m
American Airlines
Deal found 4/15![American Airlines logo]()
$326
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am
ORD
- BOG
1 stop16h 57m
American Airlines
Tue 9/157:00 am
BOG
- ORD
1 stop12h 44m
American Airlines
Deal found 4/14![American Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:05 am
ORD
- CTG
1 stop7h 21m
Multiple Airlines
Thu 5/281:31 pm
CTG
- ORD
2 stops18h 24m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$331
Best flights from Chicago to South AmericaDiscover carefully curated flight deals from Chicago to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 18, 2026.
Discover carefully curated flight deals from Chicago to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 18, 2026.
This Copa Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:21 pm
ORD
- CTG
1 stop7h 39m
Copa Airlines
Wed 5/63:05 pm
CTG
- ORD
1 stop10h 10m
Copa Airlines
Deal found 4/14![Copa Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:15 am
ORD
- CTG
1 stop8h 05m
Delta
Sat 4/252:35 pm
CTG
- ORD
1 stop9h 24m
Delta
Deal found 4/13![Delta logo]()
$359
This KAYAK deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 am
MDW
- BOG
1 stop13h 15m
LATAM Airlines
Fri 4/249:00 am
BOG
- MDW
1 stop13h 28m
LATAM Airlines
Deal found 4/13![LATAM Airlines logo]()
$365
This oojo deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:20 pm
ORD
- MDE
1 stop10h 30m
Avianca
Sat 5/2311:55 am
MDE
- ORD
1 stop9h 25m
Avianca
Deal found 4/15![Avianca logo]()
$398
This Mytrip deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:33 pm
ORD
- MDE
1 stop17h 10m
Spirit Airlines
Sun 5/312:06 pm
MDE
- ORD
1 stop18h 16m
Spirit Airlines
Deal found 4/13![Spirit Airlines logo]()
$410
This Copa Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:05 pm
ORD
- CTG
1 stop7h 55m
Copa Airlines
Tue 4/286:20 am
CTG
- ORD
1 stop18h 53m
Copa Airlines
Deal found 4/13![Copa Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:45 pm
ORD
- CTG
1 stop17h 30m
Delta
Sat 5/162:30 pm
CTG
- ORD
1 stop9h 29m
Delta
Deal found 4/15![Delta logo]()
$359
This Copa Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:05 pm
ORD
- CTG
1 stop17h 35m
Copa Airlines
Tue 4/289:45 am
CTG
- ORD
1 stop15h 28m
Copa Airlines
Deal found 4/18![Copa Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:26 am
ORD
- BOG
1 stop7h 49m
Delta
Fri 5/222:55 pm
BOG
- ORD
1 stop9h 04m
Delta
Deal found 4/14![Delta logo]()
$360
This Justfly.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:59 am
MDW
- BOG
1 stop8h 16m
LATAM Airlines
Sun 5/179:00 am
BOG
- MDW
1 stop12h 09m
LATAM Airlines
Deal found 4/13![LATAM Airlines logo]()
$432
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:07 am
ORD
- BOG
1 stop12h 08m
Delta
Sat 5/232:55 pm
BOG
- ORD
1 stop9h 12m
Delta
Deal found 4/14![Delta logo]()
$360
This Copa Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:21 pm
ORD
- CTG
1 stop16h 44m
Copa Airlines
Tue 6/912:00 pm
CTG
- ORD
1 stop16h 00m
Copa Airlines
Deal found 4/13![Copa Airlines logo]()
$363
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:15 pm
ORD
- GRU
1 stop13h 15m
United Airlines
Thu 6/410:20 pm
GRU
- ORD
Nonstop10h 25m
United Airlines
Deal found 4/13![United Airlines logo]()
$951
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:19 pm
ORD
- CTG
2 stops19h 56m
Delta
Tue 5/192:13 pm
CTG
- ORD
1 stop8h 14m
Delta
Deal found 4/14![Delta logo]()
$364
This GOL deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/911:20 pm
ORD
- GRU
1 stop21h 10m
GOL
Fri 7/246:00 am
GRU
- ORD
2 stops18h 38m
GOL
Deal found 4/16![GOL logo]()
$1,039
This Copa Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/53:21 pm
ORD
- CTG
1 stop17h 19m
Copa Airlines
Wed 6/1012:00 pm
CTG
- ORD
1 stop16h 00m
Copa Airlines
Deal found 4/15![Copa Airlines logo]()
$393
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/37:10 am
ORD
- BOG
1 stop12h 05m
Delta
Thu 5/289:00 am
BOG
- ORD
1 stop14h 59m
Delta
Deal found 4/13![Delta logo]()
$365
This LATAM Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
MDW
- MDE
2 stops26h 15m
LATAM Airlines
Fri 5/85:05 am
MDE
- MDW
2 stops16h 21m
LATAM Airlines
Deal found 4/16![LATAM Airlines logo]()
$506
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1610:45 am
MDW
- BOG
1 stop8h 30m
Delta
Sat 5/239:00 am
BOG
- MDW
1 stop12h 09m
Delta
Deal found 4/14![Delta logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/13:21 pm
ORD
- MDE
1 stop16h 54m
Copa Airlines
Tue 6/910:35 am
MDE
- ORD
1 stop17h 25m
Copa Airlines
Deal found 4/18![Copa Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:23 am
MDW
- BOG
1 stop12h 52m
Delta
Sat 5/239:00 am
BOG
- MDW
1 stop12h 09m
Delta
Deal found 4/14![Delta logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:21 pm
ORD
- MDE
1 stop16h 54m
Copa Airlines
Sat 5/3010:35 am
MDE
- ORD
1 stop14h 40m
Copa Airlines
Deal found 4/16![Copa Airlines logo]()
$405
This Copa Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:21 pm
ORD
- MDE
1 stop16h 54m
Copa Airlines
Mon 5/2510:35 am
MDE
- ORD
1 stop14h 40m
Copa Airlines
Deal found 4/18![Copa Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/37:43 pm
ORD
- BOG
2 stops17h 57m
Delta
Thu 5/212:55 pm
BOG
- ORD
2 stops22h 06m
Delta
Deal found 4/18![Delta logo]()
$370
This Copa Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/103:21 pm
ORD
- MDE
1 stop16h 54m
Copa Airlines
Sat 7/189:15 am
MDE
- ORD
1 stop14h 46m
Copa Airlines
Deal found 4/16![Copa Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:00 am
ORD
- BOG
2 stops12h 15m
Delta
Wed 5/279:00 am
BOG
- ORD
2 stops11h 14m
Delta
Deal found 4/15![Delta logo]()
$370
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/103:21 pm
ORD
- MDE
1 stop16h 54m
Copa Airlines
Mon 7/139:15 am
MDE
- ORD
1 stop18h 45m
Copa Airlines
Deal found 4/17![Copa Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:10 am
ORD
- BOG
1 stop11h 05m
Delta
Mon 5/112:55 pm
BOG
- ORD
2 stops22h 06m
Delta
Deal found 4/17![Delta logo]()
$370
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:10 pm
ORD
- GRU
1 stop14h 20m
United Airlines
Wed 5/2010:20 pm
GRU
- ORD
Nonstop10h 25m
United Airlines
Deal found 4/14![United Airlines logo]()
$951
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:07 am
ORD
- BOG
2 stops13h 03m
Delta
Wed 6/32:55 pm
BOG
- ORD
2 stops17h 50m
Delta
Deal found 4/14![Delta logo]()
$370
Last-minute flights from Chicago to South AmericaDiscover last-minute flight deals from Chicago to South America. Data last updated April 18, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to South America. Data last updated April 18, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:00 am
ORD
- BOG
1 stop17h 30m
American Airlines
Tue 4/216:30 am
BOG
- ORD
2 stops12h 52m
American Airlines
Deal found 4/15![American Airlines logo]()
$326
This Copa Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:06 am
ORD
- BOG
1 stop9h 20m
Copa Airlines
Wed 5/67:00 am
BOG
- ORD
1 stop18h 15m
Copa Airlines
Deal found 4/16![Copa Airlines logo]()
$305
This BusinessClass deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:05 am
ORD
- BOG
2 stops11h 25m
GOL
Wed 5/62:10 pm
BOG
- ORD
1 stop10h 15m
GOL
Deal found 4/16![GOL logo]()
$328
This Expedia deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:05 am
ORD
- CTG
1 stop7h 01m
Spirit Airlines
Thu 4/301:11 pm
CTG
- ORD
1 stop11h 13m
Spirit Airlines
Deal found 4/15![Spirit Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/273:05 pm
ORD
- BOG
1 stop9h 01m
Copa Airlines
Tue 5/512:08 pm
BOG
- ORD
1 stop13h 07m
Copa Airlines
Deal found 4/14![Copa Airlines logo]()
$329
This Cheapflightsfares deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:15 pm
ORD
- CTG
1 stop16h 51m
Spirit Airlines
Wed 5/61:31 pm
CTG
- ORD
2 stops22h 52m
Spirit Airlines
Deal found 4/17![Spirit Airlines logo]()
$325
This Orbitz deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:28 am
ORD
- CTG
2 stops24h 58m
Spirit Airlines
Fri 5/81:31 pm
CTG
- ORD
1 stop9h 44m
Spirit Airlines
Deal found 4/17![Spirit Airlines logo]()
$305
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:00 am
ORD
- BOG
1 stop17h 38m
American Airlines
Thu 5/216:30 am
BOG
- ORD
1 stop17h 54m
American Airlines
Deal found 4/15![American Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:05 am
ORD
- CTG
1 stop7h 21m
Multiple Airlines
Fri 5/291:31 pm
CTG
- ORD
1 stop23h 06m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$313
This KAYAK deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:05 am
ORD
- CTG
1 stop7h 21m
Spirit Airlines
Wed 5/61:31 pm
CTG
- ORD
1 stop18h 51m
Spirit Airlines
Deal found 4/15![Spirit Airlines logo]()
$324
This CheapOair deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:05 am
ORD
- CTG
1 stop7h 21m
Spirit Airlines
Fri 5/151:31 pm
CTG
- ORD
1 stop9h 44m
Spirit Airlines
Deal found 4/14![Spirit Airlines logo]()
$301
This Mytrip deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:05 am
ORD
- MDE
2 stops18h 35m
Multiple Airlines
Wed 5/205:00 am
MDE
- ORD
2 stops18h 15m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$322
One-way flights from Chicago to South AmericaSearch for one-way flight options from Chicago to South America. Find affordable one-way fares based on user searches. Data last updated April 18, 2026.
Search for one-way flight options from Chicago to South America. Find affordable one-way fares based on user searches. Data last updated April 18, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:15 pm
ORD
- CTG
1 stop16h 51m
Spirit Airlines
Deal found 4/16![Spirit Airlines logo]()
$92
This Super.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:15 pm
ORD
- CTG
1 stop16h 51m
Spirit Airlines
Deal found 4/14![Spirit Airlines logo]()
$104
This Cheapflightsfares deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:05 am
ORD
- CTG
1 stop7h 21m
Spirit Airlines
Deal found 4/16![Spirit Airlines logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/21:27 pm
ORD
- CTG
1 stop22h 39m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$109
This Cheapflightsfares deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:33 pm
ORD
- CTG
1 stop16h 53m
Spirit Airlines
Deal found 4/17![Spirit Airlines logo]()
$117
This CheapOair deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:05 am
ORD
- CTG
1 stop7h 21m
Spirit Airlines
Deal found 4/16![Spirit Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:05 am
ORD
- MDE
2 stops27h 25m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/261:22 pm
ORD
- MDE
2 stops33h 28m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:05 am
ORD
- MDE
2 stops17h 45m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/301:18 pm
ORD
- CTG
1 stop23h 08m
Spirit Airlines
Deal found 4/17![Spirit Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/103:44 pm
ORD
- MDE
2 stops40h 46m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:05 am
ORD
- MDE
2 stops18h 22m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$137
Find flight deals from Chicago to South America
Keep the following information in mind while searching for Chicago to South America flight deals. Data was last updated April 18, 2026.
Round-trip from | $301 (CheapOair) |
|---|---|
One-way from | $92 (Cheapflightsfares) |
Popular in | December |
Cheapest in | February |
Average price | $403 |
Good round-trip deal | $413 or less |
Good one-way deal | $225 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from Chicago to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCartagena
ORD - CTG
ORDCTG
Chicago O'Hare Intl
Fri 5/1
3:21 pm-11:00 pm
1 stop7h 39m
Cartagena Rafael Nunez
Wed 5/6
3:05 pm-1:15 am
1 stop10h 10m
$333
ChicagoCartagena
ORD - CTG
ORDCTG
Chicago O'Hare Intl
Sat 4/25
3:05 pm-11:00 pm
1 stop7h 55m
Cartagena Rafael Nunez
Tue 4/28
6:20 am-1:13 am
1 stop18h 53m
$348
ChicagoCartagena
ORD - CTG
ORDCTG
Chicago O'Hare Intl
Fri 4/24
3:05 pm-8:40 am
1 stop17h 35m
Cartagena Rafael Nunez
Tue 4/28
9:45 am-1:13 am
1 stop15h 28m
$353
ChicagoCartagena
ORD - CTG
ORDCTG
Chicago O'Hare Intl
Tue 4/21
5:15 am-1:20 pm
1 stop8h 05m
Cartagena Rafael Nunez
Sat 4/25
2:35 pm-11:59 pm
1 stop9h 24m
$359
ChicagoCartagena
ORD - CTG
ORDCTG
Chicago O'Hare Intl
Fri 5/8
7:45 pm-1:15 pm
1 stop17h 30m
Cartagena Rafael Nunez
Sat 5/16
2:30 pm-11:59 pm
1 stop9h 29m
$359
Quickest round-trip
ChicagoBogotá
ORD - BOG
ORDBOG
Chicago O'Hare Intl
Thu 5/14
11:26 am-7:15 pm
1 stop7h 49m
Bogotá El Dorado
Fri 5/22
2:55 pm-11:59 pm
1 stop9h 04m
$360
ChicagoBogotá
ORD - BOG
ORDBOG
Chicago O'Hare Intl
Fri 5/15
7:07 am-7:15 pm
1 stop12h 08m
Bogotá El Dorado
Sat 5/23
2:55 pm-12:07 am
1 stop9h 12m
$360
ChicagoCartagena
ORD - CTG
ORDCTG
Chicago O'Hare Intl
Sat 6/6
3:21 pm-8:05 am
1 stop16h 44m
Cartagena Rafael Nunez
Tue 6/9
12:00 pm-4:00 am
1 stop16h 00m
$363
ChicagoCartagena
ORD - CTG
ORDCTG
Chicago O'Hare Intl
Fri 5/15
5:19 pm-1:15 pm
2 stops19h 56m
Cartagena Rafael Nunez
Tue 5/19
2:13 pm-10:27 pm
1 stop8h 14m
$364
ChicagoBogotá
MDW - BOG
MDWBOG
Chicago Midway
Tue 4/21
6:00 am-7:15 pm
1 stop13h 15m
Bogotá El Dorado
Fri 4/24
9:00 am-10:28 pm
1 stop13h 28m
$365
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Chicago to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Chicago with our price prediction graph.
ORD-CTG
ORD-BOG
ORD-MDE
ORD-GRU
ORD-GIG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to South America
CHI-0SA
ORD-CTG
ORD-BOG
ORD-MDE
ORD-GRU
What is the cheapest month to book a flight from Chicago to South America?
Currently, May is the cheapest month in which you can book a flight from Chicago to South America (average of $443). Flying from Chicago to South America in December is currently the most expensive (average of $796). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to SA?
Find hourly flight availability from Chicago to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 18, 2026.
When flying from Chicago to South America, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 42% versus a flight in the afternoon.
Weekly flight availability from Chicago to South America
Explore weekly flight availability from Chicago to South America. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 18, 2026.
The most flights from CHI to 0SA are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 18, 2026.
Read reviews from past customers who have flown Copa Airlines,LATAM Airlines, andUnited Airlines from Chicago to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.8
Crew
8.1
Overall
7.5
Comfort
7.4
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Food
6.8
Crew
8.1
Overall
7.5
Comfort
7.4
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Food
6.8
Crew
8.1
Overall
7.5
Comfort
7.4
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Food
6.8
Crew
8.1
Overall
7.5
Comfort
7.4
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Food
6.8
Crew
8.1
Overall
7.5
Comfort
7.4
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Food
6.8
Crew
8.1
Overall
7.5
Comfort
7.4
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from Chicago to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to South America by cabin class
Find flights from Chicago to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and South America flights
Browse other Chicago and South America flight options. Last updated on April 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Chicago to South America flights
Consider these flights traveling from Chicago to South America.
Top 10 airlines flying from Chicago to South America
Discover the top 10 airlines that operate flights from Chicago to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$126 | Average$438 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$188 | Average$834 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$212 | Average$673 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$266 | Average$585 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$288 | Average$614 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$295 | Average$769 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$302 | Average$736 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$360 | Average$709 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$479 | Average$788 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$572 | Average$695 | FlexibilityNo cancel fee | On-time74% |