How popular is this North Carolina to Panama City flight route?

Within the past month, 36 users have taken a look at flights from North Carolina to Panama City Tocumen Intl.

What are the cheapest airlines to fly from North Carolina to Panama City one-way?

For one-way options, check prices for Delta. According to our data, you can fly for as low as $164. Users have also found prices from $169 and $189 on United Airlines and American Airlines, respectively.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the most popular routes from North Carolina to Panama City?

Most travelers choose Raleigh-Durham - Panama City Tocumen Intl, Charlotte Douglas - Panama City Tocumen Intl or Greensboro/H. Point - Panama City Tocumen Intl when deciding on the best route from North Carolina to Panama City.

What are the cheapest flights from North Carolina to Panama City?

Looking for the cheapest flight from North Carolina to Panama City? While on average our users pay $744, our data indicates the cheapest price to be $163. The most popular route (Raleigh-Durham - Panama City Tocumen Intl), is priced around $353.

What are the most popular airlines that fly from North Carolina to Panama City?

Before booking your flight from North Carolina to Panama City check out the most popular airlines for this route: American Airlines, Copa Airlines or Delta.

How far in advance should I book a flight from North Carolina to Panama City?

To save up to 59% on this flight, we recommend booking at least 22 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from North Carolina to Panama City from $558 1-2 weeks out and tickets from $716 for flights departing within the next 72 hours.

What is the cheapest month to fly from North Carolina to Panama City?

Our data shows that September tends to be the cheapest month to fly to Panama City from North Carolina. Users have commonly found prices around $570 for the month, but tickets can be as low as $467. Due to multiple factors, prepare for potentially higher prices in December.

What airport do you fly into for flights to Panama City from North Carolina?

If you book a flight to Panama City from North Carolina, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City.

Can I find deals for flights from North Carolina to Panama City that include hotel bookings?

Yes. In addition to deals on North Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from North Carolina to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama City.

Can I find deals for business class flights from North Carolina to Panama City?

Yes. Cheapflights offers flight deals from North Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$164+ Flights from North Carolina to Panama City

Q: How much does it cost to fly round-trip from North Carolina to Panama City?

Airfare is below average for this route at the moment. North Carolina to Panama City flights typically cost between $391 and $530 in August. The cheapest round-trip price found within the last 3 days was $353 on Copa Airlines (Aug 25-Sep 7).

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Find cheap flights from North Carolina to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from North Carolina to Panama City

Round-trip from	$353 (Copa Airlines)
One-way from	$164 (Delta)
Popular in	December
Cheapest in	September
Average price	$613
Good round-trip deal	$359 or less
Good one-way deal	$200 or less

From North Carolina to Panama City Tocumen Intl

Search Deals

One-way flight from North Carolina to Panama City Tocumen Intl

Search Deals

Highest demand for flights based on searches. 12% potential increase in price ($79 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in July 2025

Search Deals

Price to beat on a round-trip flight from North Carolina to Panama City Tocumen Intl.

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Price to beat on a one-way flight from North Carolina to Panama City Tocumen Intl.

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Find flight deals from North Carolina to Panama City

Cheapest flights from North Carolina to Panama City
Explore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Mon 8/254:22 pmRDU - PTY

Nonstop4h 24mCopa Airlines

Sun 9/78:57 amPTY - RDU

Nonstop4h 30mCopa Airlines

Deal found 7/30

$353

Tue 10/145:15 amRDU - PTY

1 stop8h 41mDelta

Wed 10/222:21 pmPTY - RDU

1 stop8h 41mDelta

Deal found 7/30

$367

Fri 9/196:00 amRDU - PTY

1 stop9h 31mAmerican Airlines

Sun 9/283:31 pmPTY - RDU

1 stop7h 14mAmerican Airlines

Deal found 7/30

$372

Wed 9/36:15 amORF - PTY

1 stop7h 40mAmerican Airlines

Fri 9/123:31 pmPTY - ORF

1 stop7h 28mAmerican Airlines

Deal found 7/29

$403

Wed 8/276:15 amORF - PTY

2 stops13h 22mUnited Airlines

Mon 9/83:30 pmPTY - ORF

2 stops18h 32mUnited Airlines

Deal found 7/29

$408

Thu 10/210:17 amCLT - PTY

2 stops14h 53mMultiple Airlines

Wed 10/83:20 amPTY - CLT

2 stops16h 41mMultiple Airlines

Deal found 7/31

$415

Sat 9/65:30 amORF - PTY

1 stop8h 20mDelta

Tue 9/92:05 pmPTY - ORF

1 stop9h 19mDelta

Deal found 7/28

$423

Mon 9/225:45 amORF - PTY

2 stops16h 25mMultiple Airlines

Tue 9/233:20 amPTY - ORF

2 stops18h 28mMultiple Airlines

Deal found 7/29

$431

Thu 11/136:00 amGSO - PTY

1 stop7h 55mUnited Airlines

Tue 11/1810:00 amPTY - GSO

1 stop11h 03mUnited Airlines

Deal found 7/31

$465

Thu 9/255:18 amCLT - PTY

1 stop10h 13mAmerican Airlines

Tue 9/301:45 pmPTY - CLT

1 stop16h 40mAmerican Airlines

Deal found 7/30

$467

Thu 11/138:11 pmGSO - PTY

2 stops17h 25mAmerican Airlines

Tue 11/182:43 pmPTY - GSO

2 stops19h 06mAmerican Airlines

Deal found 7/31

$472

Thu 9/258:03 pmFAY - PTY

2 stops19h 28mAmerican Airlines

Tue 9/301:45 pmPTY - FAY

2 stops19h 00mAmerican Airlines

Deal found 7/30

$472

Best flights from North Carolina to Panama City
Discover carefully curated flight deals from North Carolina to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 31, 2025.

Mon 8/254:22 pmRDU - PTY

Nonstop4h 24mCopa Airlines

Sun 9/78:57 amPTY - RDU

Nonstop4h 30mCopa Airlines

Deal found 7/30

$353

Tue 10/145:15 amRDU - PTY

1 stop8h 41mDelta

Wed 10/222:21 pmPTY - RDU

1 stop8h 41mDelta

Deal found 7/30

$367

Fri 9/196:00 amRDU - PTY

1 stop9h 31mAmerican Airlines

Sun 9/283:31 pmPTY - RDU

1 stop7h 14mAmerican Airlines

Deal found 7/30

$372

Wed 8/276:15 amORF - PTY

2 stops13h 22mUnited Airlines

Mon 9/83:30 pmPTY - ORF

2 stops18h 32mUnited Airlines

Deal found 7/29

$408

Thu 10/210:17 amCLT - PTY

2 stops14h 53mMultiple Airlines

Wed 10/83:20 amPTY - CLT

2 stops16h 41mMultiple Airlines

Deal found 7/31

$415

Wed 9/36:15 amORF - PTY

1 stop7h 40mAmerican Airlines

Fri 9/123:31 pmPTY - ORF

1 stop7h 28mAmerican Airlines

Deal found 7/29

$403

Sat 9/65:30 amORF - PTY

1 stop8h 20mDelta

Tue 9/92:05 pmPTY - ORF

1 stop9h 19mDelta

Deal found 7/28

$423

Mon 9/225:45 amORF - PTY

2 stops16h 25mMultiple Airlines

Tue 9/233:20 amPTY - ORF

2 stops18h 28mMultiple Airlines

Deal found 7/29

$431

Thu 11/136:00 amGSO - PTY

1 stop7h 55mUnited Airlines

Tue 11/1810:00 amPTY - GSO

1 stop11h 03mUnited Airlines

Deal found 7/31

$465

Thu 9/255:18 amCLT - PTY

1 stop10h 13mAmerican Airlines

Tue 9/301:45 pmPTY - CLT

1 stop16h 40mAmerican Airlines

Deal found 7/30

$467

Fri 9/265:30 amCLT - PTY

1 stop8h 25mDelta

Wed 10/12:10 pmPTY - CLT

1 stop8h 36mDelta

Deal found 7/31

$487

Wed 8/278:00 amAVL - PTY

3 stops27h 25mMultiple Airlines

Sat 8/303:20 amPTY - AVL

3 stops17h 48mMultiple Airlines

Deal found 7/31

$501

Last-minute flights from North Carolina to Panama City
Discover last-minute flight deals from North Carolina to Panama City. Data last updated July 31, 2025 and is based on user searches.

Wed 8/68:10 pmORF - PTY

2 stops21h 02mUnited Airlines

Mon 8/113:30 pmPTY - ORF

2 stops22h 44mUnited Airlines

Deal found 7/30

$429

Wed 8/67:00 amCLT - PTY

1 stop12h 37mUnited Airlines

Wed 8/1310:00 amPTY - CLT

1 stop10h 57mUnited Airlines

Deal found 7/30

$577

Wed 8/66:10 amMYR - PTY

3 stops43h 00mMultiple Airlines

Wed 8/135:25 pmPTY - MYR

3 stops25h 20mMultiple Airlines

Deal found 7/30

$601

Thu 8/78:04 pmORF - PTY

2 stops19h 26mAmerican Airlines

Sun 8/103:30 pmPTY - ORF

2 stops23h 42mAmerican Airlines

Deal found 7/30

$449

Thu 8/74:38 pmTRI - PTY

2 stops22h 52mAmerican Airlines

Thu 8/143:30 pmPTY - TRI

2 stops19h 15mAmerican Airlines

Deal found 7/31

$582

Thu 8/75:48 pmAVL - PTY

2 stops21h 42mAmerican Airlines

Sun 8/173:30 pmPTY - AVL

2 stops24h 31mAmerican Airlines

Deal found 7/30

$607

Thu 8/76:19 pmFAY - PTY

2 stops21h 11mAmerican Airlines

Mon 8/113:30 pmPTY - FAY

2 stops18h 48mAmerican Airlines

Deal found 7/29

$632

Thu 8/79:05 amORF - PTY

3 stops26h 20mMultiple Airlines

Sun 8/1011:20 amPTY - ORF

3 stops34h 15mMultiple Airlines

Deal found 7/30

$652

Fri 8/88:55 amCLT - PTY

1 stop6h 35mAmerican Airlines

Sat 8/163:30 pmPTY - CLT

1 stop14h 56mAmerican Airlines

Deal found 7/31

$597

Fri 8/86:49 amRDU - PTY

1 stop12h 48mUnited Airlines

Sun 8/107:55 amPTY - RDU

1 stop13h 05mUnited Airlines

Deal found 7/30

$739

Sat 8/910:51 amAVL - PTY

3 stops24h 34mMultiple Airlines

Sun 8/178:10 pmPTY - AVL

3 stops24h 41mMultiple Airlines

Deal found 7/30

$482

Sat 8/98:48 amCLT - PTY

2 stops16h 22mMultiple Airlines

Sun 8/173:40 pmPTY - CLT

2 stops19h 58mMultiple Airlines

Deal found 7/30

$588

One-way flights from North Carolina to Panama City
Search for one-way flight options from North Carolina to Panama City. Find affordable one-way fares based on user searches. Data last updated July 31, 2025.

Mon 10/136:05 amGSO - PTY

1 stop7h 51mDelta

Deal found 7/31

$164

Sun 8/35:05 pmORF - PTY

2 stops24h 07mUnited Airlines

Deal found 7/29

$169

Mon 8/187:56 pmRDU - PTY

2 stops26h 14mMultiple Airlines

Deal found 7/31

$176

Wed 9/37:00 amCLT - PTY

2 stops18h 45mMultiple Airlines

Deal found 7/31

$178

Sat 8/166:29 amORF - PTY

1 stop9h 01mAmerican Airlines

Deal found 7/31

$189

Mon 9/15:35 amCLT - PTY

1 stop8h 15mDelta

Deal found 7/31

$221

Wed 9/34:36 pmAVL - PTY

2 stops22h 55mAmerican Airlines

Deal found 7/31

$221

Thu 10/306:52 pmGSO - PTY

2 stops20h 08mAmerican Airlines

Deal found 7/31

$226

Mon 8/187:53 pmRDU - PTY

1 stop19h 37mAmerican Airlines

Deal found 7/30

$263

Fri 12/129:10 amCLT - PTY

1 stop6h 15mAmerican Airlines

Deal found 7/30

$271

Sat 8/97:00 amCLT - PTY

1 stop10h 12mUnited Airlines

Deal found 7/30

$291

Sat 8/165:30 amORF - PTY

3 stops29h 55mMultiple Airlines

Deal found 7/31

$294

Cheapflights Fare Finder

Use the filters below to find and compare flights from North Carolina to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 8/25

4:22 pm-7:46 pm

Nonstop4h 24m

Panama City Tocumen Intl

Sun 9/7

8:57 am-2:27 pm

Nonstop4h 30m

$353

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Tue 10/14

5:15 am-12:56 pm

1 stop8h 41m

Panama City Tocumen Intl

Wed 10/22

2:21 pm-12:02 am

1 stop8h 41m

$367

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 9/19

6:00 am-2:31 pm

1 stop9h 31m

Panama City Tocumen Intl

Sun 9/28

3:31 pm-11:45 pm

1 stop7h 14m

$372

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 9/3

6:15 am-12:55 pm

1 stop7h 40m

Panama City Tocumen Intl

Fri 9/12

3:31 pm-11:59 pm

1 stop7h 28m

$403

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 8/27

6:15 am-6:37 pm

2 stops13h 22m

Panama City Tocumen Intl

Mon 9/8

3:30 pm-11:02 am

2 stops18h 32m

$408

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 10/2

10:17 am-12:10 am

2 stops14h 53m

Panama City Tocumen Intl

Wed 10/8

3:20 am-9:01 pm

2 stops16h 41m

$415

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Sat 9/6

5:30 am-12:50 pm

1 stop8h 20m

Panama City Tocumen Intl

Tue 9/9

2:05 pm-12:24 am

1 stop9h 19m

$423

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Mon 9/22

5:45 am-9:10 pm

2 stops16h 25m

Panama City Tocumen Intl

Tue 9/23

3:20 am-10:48 pm

2 stops18h 28m

$431

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

Thu 11/13

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Tue 11/18

10:00 am-9:03 pm

1 stop11h 03m

$465

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 9/25

5:18 am-2:31 pm

1 stop10h 13m

Panama City Tocumen Intl

Tue 9/30

1:45 pm-7:25 am

1 stop16h 40m

$467

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 53 results

...

Best time to book a flight from North Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from North Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama City

What is the cheapest month to book a flight from North Carolina to Panama City?

Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama City (average of $478). Flying from North Carolina to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to PTY?

When flying from North Carolina to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from North Carolina to Panama City?

Reviews of airlines servicing Panama City

Read through reviews of airlines operating flights from North Carolina to Panama City, such as Delta, Copa Airlines, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,981 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Copa Airlines

7.5

Good

1,493 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,900 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

WestJet

7.2

Good

2,978 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly into for flights to Panama City from North Carolina?
If you book a flight to Panama City from North Carolina, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City.
How popular is this North Carolina to Panama City flight route?
Within the past month, 36 users have taken a look at flights from North Carolina to Panama City Tocumen Intl.
What are the cheapest airlines to fly from North Carolina to Panama City one-way?
For one-way options, check prices for Delta. According to our data, you can fly for as low as $164. Users have also found prices from $169 and $189 on United Airlines and American Airlines, respectively.
What are the most popular routes from North Carolina to Panama City?
Most travelers choose Raleigh-Durham - Panama City Tocumen Intl, Charlotte Douglas - Panama City Tocumen Intl or Greensboro/H. Point - Panama City Tocumen Intl when deciding on the best route from North Carolina to Panama City.
What are the cheapest flights from North Carolina to Panama City?
Looking for the cheapest flight from North Carolina to Panama City? While on average our users pay $744, our data indicates the cheapest price to be $163. The most popular route (Raleigh-Durham - Panama City Tocumen Intl), is priced around $353.
Can I find deals for flights from North Carolina to Panama City that include hotel bookings?
Yes. In addition to deals on North Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from North Carolina to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama City.
Can I find deals for business class flights from North Carolina to Panama City?
Yes. Cheapflights offers flight deals from North Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from North Carolina to Panama City?
Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama City (average of $478). Flying from North Carolina to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from North Carolina to Panama City

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$249	Average$587	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$282	Average$413	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$297	Average$579	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$409	Average$508	FlexibilityNo cancel fee	On-time69%

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$164+ Cheap flights from North Carolina to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from North Carolina to Panama City with Cheapflights

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3. Compare prices and book

Cheap flight deals from North Carolina to Panama City

Keep the following information in mind while searching for North Carolina to Panama City flight deals. Data was last updated July 31, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from North Carolina to Panama City

Cheapest flights from North Carolina to Panama CityExplore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Explore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from North Carolina to Panama City that are best for you.

Best time to book a flight from North Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from North Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama City

What is the cheapest month to book a flight from North Carolina to Panama City?

What is the cheapest time of day to fly from NC to PTY?

Find hourly flight availability from North Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

How much does it cost to fly round-trip from North Carolina to Panama City?

Reviews of airlines servicing Panama City

Read through reviews of airlines operating flights from North Carolina to Panama City, such as Delta, Copa Airlines, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Panama City from North Carolina?

How popular is this North Carolina to Panama City flight route?

What are the cheapest airlines to fly from North Carolina to Panama City one-way?

What are the most popular routes from North Carolina to Panama City?

What are the cheapest flights from North Carolina to Panama City?

Can I find deals for flights from North Carolina to Panama City that include hotel bookings?

How can I find direct flights from North Carolina to Panama City?

Can I find deals for business class flights from North Carolina to Panama City?

What is the cheapest month to book a flight from North Carolina to Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for North Carolina to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from North Carolina to Panama City

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Cheapest flights from North Carolina to Panama City
Explore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.