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Panama City

$164+ Cheap flights from North Carolina to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — PTY
Nov 19 — Nov 261
Wed 11/19
Wed 11/26
1 adult, Economy
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Find flight deals from North Carolina to Panama City

Cheapest flights from North Carolina to Panama City
Explore the most affordable flight options available from North Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2025.

This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/175:30 amCLT - PTY
1 stop8h 42mDelta
Mon 11/243:37 pmPTY - CLT
1 stop8h 13mDelta
Deal found 10/18$400
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1710:01 pmCLT - PTY
2 stops15h 48mAmerican Airlines
Thu 11/202:43 pmPTY - CLT
2 stops15h 52mAmerican Airlines
Deal found 10/20$404
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/118:05 pmORF - PTY
2 stops18h 40mUnited Airlines
Mon 11/174:41 pmPTY - ORF
2 stops21h 53mUnited Airlines
Deal found 10/19$408
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/285:15 amORF - PTY
1 stop14h 44mDelta
Wed 12/33:46 pmPTY - ORF
1 stop8h 30mDelta
Deal found 10/17$424
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/285:21 pmORF - PTY
2 stops20h 22mAmerican Airlines
Wed 12/32:50 pmPTY - ORF
1 stop9h 09mAmerican Airlines
Deal found 10/17$428
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/173:55 pmRDU - PTY
1 stop16h 11mMultiple Airlines
Tue 11/2512:33 pmPTY - RDU
1 stop8h 17mMultiple Airlines
Deal found 10/19$433
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/110:45 pmCLT - PTY
1 stop14h 58mAmerican Airlines
Thu 1/154:46 pmPTY - CLT
1 stop7h 11mAmerican Airlines
Deal found 10/18$434
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/154:03 pmMYR - PTY
2 stops21h 44mAmerican Airlines
Thu 3/121:50 pmPTY - MYR
2 stops19h 02mAmerican Airlines
Deal found 10/19$440
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/193:14 pmRDU - PTY
Nonstop4h 32mCopa Airlines
Wed 12/38:57 amPTY - RDU
Nonstop4h 28mCopa Airlines
Deal found 10/19$441
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:30 amORF - PTY
1 stop8h 42mDelta
Sat 11/228:05 amPTY - ORF
1 stop10h 29mDelta
Deal found 10/19$444
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/168:39 pmRDU - PTY
2 stops17h 10mAmerican Airlines
Mon 11/242:43 pmPTY - RDU
2 stops17h 20mAmerican Airlines
Deal found 10/18$447
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:58 pmORF - PTY
2 stops18h 51mAmerican Airlines
Sat 11/222:43 pmPTY - ORF
1 stop9h 32mAmerican Airlines
Deal found 10/19$448

Cheap flight deals from North Carolina to Panama City

Keep the following information in mind while searching for North Carolina to Panama City flight deals. Data was last updated October 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$394
(Delta)

One-way from

$164
(Delta)

Popular in

December

Cheapest in

November

Average price

$398

Good round-trip deal

$344 or less

Good one-way deal

$150 or less
Provider with most accurate pricing for Raleigh-Durham-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Panama City Tocumen Intl flights.
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From North Carolina to Panama City Tocumen Intl
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One-way flight from North Carolina to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($37 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from North Carolina to Panama City Tocumen Intl.
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Price to beat on a one-way flight from North Carolina to Panama City Tocumen Intl.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
Use the filters below to find and compare flights from North Carolina to Panama City that are best for you.

Fly from

North Carolina

Fly to

Panama City

Route

Depart

Return

Price

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

Wed 3/18

5:25 am-12:55 pm

1 stop8h 30m

Panama City Tocumen Intl

Tue 4/21

2:20 pm-11:56 pm

1 stop8h 36m

$394

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 12/1

8:19 pm-1:43 pm

1 stop17h 24m

Panama City Tocumen Intl

Thu 12/4

2:50 pm-10:57 pm

1 stop8h 07m

$400

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 1/29

7:38 pm-1:27 pm

1 stop17h 49m

Panama City Tocumen Intl

Tue 2/3

2:27 pm-10:59 pm

1 stop8h 32m

$404

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 11/17

10:01 pm-1:49 pm

2 stops15h 48m

Panama City Tocumen Intl

Thu 11/20

2:43 pm-6:35 am

2 stops15h 52m

$404

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 11/17

10:01 pm-1:49 pm

2 stops15h 48m

Panama City Tocumen Intl

Mon 11/24

2:43 pm-6:35 am

2 stops15h 52m

$404

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Tue 11/11

8:05 pm-2:45 pm

2 stops18h 40m

Panama City Tocumen Intl

Mon 11/17

4:41 pm-2:34 pm

2 stops21h 53m

$408

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 2/12

6:25 am-7:38 pm

2 stops13h 13m

Panama City Tocumen Intl

Tue 2/17

4:41 pm-10:28 pm

1 stop29h 47m

$417

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Fri 11/28

5:15 am-7:59 pm

1 stop14h 44m

Panama City Tocumen Intl

Wed 12/3

3:46 pm-12:16 am

1 stop8h 30m

$424

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 2/19

6:10 am-8:02 pm

2 stops13h 52m

Panama City Tocumen Intl

Sat 2/28

4:41 pm-2:23 pm

2 stops21h 42m

$426

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

Wed 3/18

8:54 pm-12:10 pm

2 stops16h 16m

Panama City Tocumen Intl

Tue 4/21

1:55 pm-11:14 pm

1 stop8h 19m

$440

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/17

Showing 1-10 of 60 results
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Best time to book a flight from North Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama City

What is the cheapest month to book a flight from North Carolina to Panama City?

Currently, August is the cheapest month in which you can book a flight from North Carolina to Panama City (average of $234). Flying from North Carolina to Panama City in June is currently the most expensive (average of $394). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to PTY?

Find hourly flight availability from North Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 20, 2025.

One of the essential ways to save on airfare from North Carolina to Panama City is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 30% on airfare.

How much does it cost to fly round-trip from North Carolina to Panama City?

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from North Carolina?

    If you book a flight to Panama City from North Carolina, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City.

  • How popular is this North Carolina to Panama City flight route?

    Within the past month, 23 users have taken a look at flights from North Carolina to Panama City Tocumen Intl.

  • How long is the flight from North Carolina to Panama City?

    A quick flight from North Carolina to Panama City can take about 8h 30m. Delta provides one of the quickest options available for as low as $394. There are 1867 mi between North Carolina and Panama City. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from North Carolina to Panama City one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $164. Users have also found prices from $169 and $221 on American Airlines and United Airlines, respectively.

  • What are the most popular routes from North Carolina to Panama City?

    Most travelers choose Raleigh-Durham - Panama City Tocumen Intl, Charlotte Douglas - Panama City Tocumen Intl or Greensboro/H. Point - Panama City Tocumen Intl when deciding on the best route from North Carolina to Panama City.

  • What are the cheapest flights from North Carolina to Panama City?

    Looking for the cheapest flight from North Carolina to Panama City? While on average our users pay $382, our data indicates the cheapest price to be $93. The most popular route (Raleigh-Durham - Panama City Tocumen Intl), is priced around $441.

  • Can I find deals for flights from North Carolina to Panama City that include hotel bookings?

    Yes. In addition to deals on North Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama City.

  • Can I find deals for business class flights from North Carolina to Panama City?

    Yes. Cheapflights offers flight deals from North Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Panama City?

    Currently, August is the cheapest month in which you can book a flight from North Carolina to Panama City (average of $234). Flying from North Carolina to Panama City in June is currently the most expensive (average of $394). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for North Carolina to Panama City

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Top 4 airlines flying from North Carolina to Panama City

Discover the top 4 airlines that operate flights from North Carolina to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$249Average$588FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$282Average$443FlexibilityNo cancel feeOn-time70%
DeltaCheapest$357Average$550FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$409Average$511FlexibilityNo cancel feeOn-time69%

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