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$107+ Cheap flights from Florence, SC (FLO) to North America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — LAX
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Florence to North America

Keep the following information in mind while searching for Florence to North America flight deals. Data was last updated September 11, 2025.

Round-trip from

$306
(American Airlines)

One-way from

$107
(American Airlines)

Good round-trip deal

$391 or less

Good one-way deal

$417 or less
From Florence to North America
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One-way flight from Florence to North America
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Price to beat on a one-way flight from Florence to North America.
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Find flight deals from Florence to North America

Cheapest flights from Florence to North America
Explore the most affordable flight options available from Florence to North America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1111:11 amFLO - ORD
1 stop5h 54mAmerican Airlines
Sat 10/187:10 amORD - FLO
1 stop5h 54mAmerican Airlines
Deal found 9/11$159
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2612:27 pmFLO - HOU
2 stops8h 44mAmerican Airlines
Tue 9/302:33 pmHOU - FLO
2 stops7h 43mAmerican Airlines
Deal found 9/11$289
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:14 amFLO - ATL
2 stops14h 13mAmerican Airlines
Sat 11/18:48 amATL - FLO
2 stops10h 59mAmerican Airlines
Deal found 9/10$306
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:37 pmFLO - ORD
1 stop6h 35mAmerican Airlines
Tue 9/309:51 amORD - FLO
1 stop6h 21mAmerican Airlines
Deal found 9/11$320
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:14 amFLO - MCO
2 stops13h 30mAmerican Airlines
Wed 10/16:10 amMCO - FLO
2 stops11h 02mAmerican Airlines
Deal found 9/10$369
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:14 amFLO - SFO
1 stop8h 16mAmerican Airlines
Tue 9/3012:30 pmSFO - FLO
1 stop7h 46mAmerican Airlines
Deal found 9/11$375
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:11 amFLO - SFO
1 stop9h 43mAmerican Airlines
Tue 12/27:15 amSFO - FLO
1 stop6h 54mAmerican Airlines
Deal found 9/10$377
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1912:27 pmFLO - HOU
2 stops8h 44mAmerican Airlines
Sun 9/216:00 amHOU - FLO
2 stops9h 32mAmerican Airlines
Deal found 9/10$379
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2511:11 amFLO - SFO
2 stops12h 03mAmerican Airlines
Tue 12/27:15 amSFO - FLO
1 stop6h 54mAmerican Airlines
Deal found 9/10$382
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1711:11 amFLO - JAN
2 stops11h 50mAmerican Airlines
Tue 10/217:20 amJAN - FLO
2 stops14h 53mAmerican Airlines
Deal found 9/9$385
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1811:11 amFLO - JAN
1 stop5h 52mAmerican Airlines
Wed 10/225:46 pmJAN - FLO
1 stop4h 27mAmerican Airlines
Deal found 9/9$387
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:14 amFLO - JAN
1 stop4h 18mAmerican Airlines
Sat 10/115:10 amJAN - FLO
1 stop4h 36mAmerican Airlines
Deal found 9/9$397

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to North America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Florence to North America that are best for you.

Fly from

Florence

Fly to

North America

Route

Depart

Return

Price

FlorenceChicago

FLO - ORD

FLOORD

Florence

Sat 10/11

11:11 am-4:05 pm

1 stop5h 54m

Chicago O'Hare Intl

Sat 10/18

7:10 am-2:04 pm

1 stop5h 54m

$159

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Fri 9/26

12:27 pm-8:11 pm

2 stops8h 44m

Houston Hobby

Tue 9/30

2:33 pm-11:16 pm

2 stops7h 43m

$289

FlorenceAtlanta

FLO - ATL

FLOATL

Florence

Sat 10/25

5:14 am-7:27 pm

2 stops14h 13m

Atlanta Hartsfield-Jackson

Sat 11/1

8:48 am-7:47 pm

2 stops10h 59m

$306

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 9/26

5:37 pm-11:12 pm

1 stop6h 35m

Chicago O'Hare Intl

Tue 9/30

9:51 am-5:12 pm

1 stop6h 21m

$320

FlorenceChicago

FLO - ORD

FLOORD

Florence

Wed 3/4

2:33 pm-7:29 pm

1 stop5h 56m

Chicago O'Hare Intl

Sat 3/7

7:00 am-2:03 pm

1 stop6h 03m

$346

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Wed 9/24

6:14 am-7:44 pm

2 stops13h 30m

Orlando

Wed 10/1

6:10 am-5:12 pm

2 stops11h 02m

$369

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Fri 9/26

6:14 am-11:30 am

1 stop8h 16m

San Francisco

Tue 9/30

12:30 pm-11:16 pm

1 stop7h 46m

$375

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Wed 11/26

11:11 am-5:54 pm

1 stop9h 43m

San Francisco

Tue 12/2

7:15 am-5:09 pm

1 stop6h 54m

$377

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Tue 11/25

11:11 am-8:14 pm

2 stops12h 03m

San Francisco

Tue 12/2

7:15 am-5:09 pm

1 stop6h 54m

$382

FlorenceJackson

FLO - JAN

FLOJAN

Florence

Fri 10/17

11:11 am-10:01 pm

2 stops11h 50m

Jackson-Evers Intl

Tue 10/21

7:20 am-11:13 pm

2 stops14h 53m

$385

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 34 results
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Best time to book a flight from Florence to North America

Have a flexible travel schedule? Discover the best time to fly to North America from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to North America

What is the cheapest month to book a flight from Florence, South Carolina to North America?

Currently, January is the cheapest month in which you can book a flight from Florence, South Carolina to North America (average of $246). Flying from Florence, South Carolina to North America in March is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing North America

Get insights into the airlines that provide service to North America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North America. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with American Airlines from Florence to North America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Food

6.4

Overall

7.2

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Food

6.4

Overall

7.2

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Florence to North America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to North America?

    Florence (FLO), located 2.3 mi from the city center, is the airport you fly out of when you book flights from Florence to North America.

  • How long is the flight from Florence, South Carolina to North America?

    American Airlines can get you from Florence, South Carolina to North America in just under 5h 54m. Your travel time can differ by up to . The distance from Florence, South Carolina to North America is about 697 mi.

  • What are the most popular routes from Florence, South Carolina to North America?

    The most popular route from Florence, South Carolina to North America is Florence - Jackson-Evers Intl. You may also consider Florence - Chicago O'Hare Intl or Florence - Tampa.

  • Can I find deals for flights from Florence to North America that include hotel bookings?

    Yes. In addition to deals on Florence to North America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to North America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to North America.

  • Can I find deals for business class flights from Florence to North America?

    Yes. Cheapflights offers flight deals from Florence to North America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to North America?

    Currently, January is the cheapest month in which you can book a flight from Florence, South Carolina to North America (average of $246). Flying from Florence, South Carolina to North America in March is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Florence to North America

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Top airline flying from Florence to North America

Discover the top airline that operate flights from Florence to North America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$213Average$497FlexibilityNo cancel feeOn-time71%

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