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$225+ Cheap flights from Des Moines to Milwaukee (DSM - MKE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MKE
Mar 18 — Mar 251
Wed 3/18
Wed 3/25
1 adult, Economy
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Cheap flight deals from Des Moines to Milwaukee

Cheapest flights from Des Moines to Milwaukee
Explore the most affordable flight options available from Des Moines to Milwaukee. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 16, 2026.

This Southwest deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:35 am
DSM
-
MKE
1 stop6h 10m
Southwest
Mon 4/65:40 am
MKE
-
DSM
1 stop8h 00m
Southwest
Deal found 2/13$276
This Delta deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/310:51 am
DSM
-
MKE
1 stop4h 25m
Delta
Sun 4/59:21 am
MKE
-
DSM
1 stop6h 21m
Delta
Deal found 2/15$287
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:44 pm
DSM
-
MKE
1 stop13h 16m
American Airlines
Mon 3/95:00 am
MKE
-
DSM
1 stop3h 59m
American Airlines
Deal found 2/15$290
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:15 pm
DSM
-
MKE
1 stop3h 44m
United Airlines
Sun 9/207:00 am
MKE
-
DSM
1 stop3h 20m
United Airlines
Deal found 2/12$299
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:20 am
DSM
-
MKE
1 stop3h 40m
United Airlines
Sun 4/57:22 pm
MKE
-
DSM
1 stop3h 37m
United Airlines
Deal found 2/15$301
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:25 pm
DSM
-
MKE
1 stop4h 51m
Delta
Tue 4/76:30 am
MKE
-
DSM
1 stop3h 39m
Delta
Deal found 2/14$310
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:15 pm
DSM
-
MKE
1 stop3h 44m
United Airlines
Sun 9/207:00 am
MKE
-
DSM
1 stop3h 20m
United Airlines
Deal found 2/12$311
This Southwest deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:40 am
DSM
-
MKE
1 stop5h 20m
Southwest
Sun 9/205:25 pm
MKE
-
DSM
2 stops5h 10m
Southwest
Deal found 2/12$312
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:40 am
DSM
-
MKE
1 stop28h 03m
American Airlines
Thu 4/97:01 am
MKE
-
DSM
1 stop6h 45m
American Airlines
Deal found 2/13$326
This Southwest deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:30 am
DSM
-
MKE
1 stop6h 15m
Southwest
Tue 4/78:00 am
MKE
-
DSM
2 stops14h 10m
Southwest
Deal found 2/14$332

Find flight deals from Des Moines to Milwaukee

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Milwaukee (MKE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$239
(American Airlines)

One-way from

$225
(American Airlines)

Popular in

December

Cheapest in

March
Provider with most accurate pricing for Des Moines-Milwaukee-Mitchell flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Milwaukee-Mitchell flights.
Search Deals
From Des Moines to Milwaukee-Mitchell
Search Deals
One-way flight from Des Moines to Milwaukee-Mitchell
Search Deals
Highest demand for flights based on searches. 34% potential increase in price ($168 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 16% potential price decrease ($44 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Milwaukee that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 16, 2026.
Use the filters below to find and compare flights from Des Moines to Milwaukee that are best for you.

Fly from

Des Moines

Fly to

Milwaukee

Route

Depart

Return

Price

Des MoinesMilwaukee

DSM - MKE

DSMMKE

Des Moines

Mon 3/30

5:35 am-11:45 am

1 stop6h 10m

Milwaukee-Mitchell

Mon 4/6

5:40 am-1:40 pm

1 stop8h 00m

$276

Des MoinesMilwaukee

DSM - MKE

DSMMKE

Des Moines

Fri 4/3

10:51 am-3:16 pm

1 stop4h 25m

Milwaukee-Mitchell

Sun 4/5

9:21 am-3:42 pm

1 stop6h 21m

$287

Des MoinesMilwaukee

DSM - MKE

DSMMKE

Des Moines

Fri 3/6

7:44 pm-9:00 am

1 stop13h 16m

Milwaukee-Mitchell

Mon 3/9

5:00 am-8:59 am

1 stop3h 59m

$290

Des MoinesMilwaukee

DSM - MKE

DSMMKE

Des Moines

Fri 4/3

6:20 am-10:00 am

1 stop3h 40m

Milwaukee-Mitchell

Sun 4/5

7:22 pm-10:59 pm

1 stop3h 37m

$301

Des MoinesMilwaukee

DSM - MKE

DSMMKE

Des Moines

Tue 3/31

4:25 pm-9:16 pm

1 stop4h 51m

Milwaukee-Mitchell

Tue 4/7

6:30 am-10:09 am

1 stop3h 39m

$310

Des MoinesMilwaukee

DSM - MKE

DSMMKE

Des Moines

Mon 4/6

6:40 am-10:43 am

1 stop28h 03m

Milwaukee-Mitchell

Thu 4/9

7:01 am-1:46 pm

1 stop6h 45m

$326

Des MoinesMilwaukee

DSM - MKE

DSMMKE

Des Moines

Tue 3/31

5:30 am-11:45 am

1 stop6h 15m

Milwaukee-Mitchell

Tue 4/7

8:00 am-10:10 pm

2 stops14h 10m

$332

Des MoinesMilwaukee

DSM - MKE

DSMMKE

Des Moines

Fri 3/6

5:35 am-12:00 pm

2 stops6h 25m

Milwaukee-Mitchell

Mon 3/9

9:50 am-11:15 pm

2 stops13h 25m

$387

Des MoinesMilwaukee

DSM - MKE

DSMMKE

Des Moines

Sat 2/21

7:44 pm-7:49 am

1 stop12h 05m

$225

Des MoinesMilwaukee

DSM - MKE

DSMMKE

Des Moines

Sat 2/21

5:10 am-2:50 pm

2 stops9h 40m

$280

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/15

Showing 1-10 of 13 results
1
2

Compare providers for flights from Des Moines to Milwaukee

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Milwaukee in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Milwaukee flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Milwaukee flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Milwaukee flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Milwaukee flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Milwaukee flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Milwaukee

Have a flexible travel schedule? Discover the best time to fly to Milwaukee from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Milwaukee

What is the cheapest month to book a flight from Des Moines to Milwaukee?

Currently, February is the cheapest month in which you can book a flight from Des Moines to Milwaukee (average of $142). Flying from Des Moines to Milwaukee in January is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Milwaukee

Get insights into the airlines that provide service to Milwaukee. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Milwaukee. Reviews last updated February 16, 2026.
Read through reviews of airlines operating flights from Des Moines to Milwaukee, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,294 reviews

Overall

7.2

Boarding

7.5

Food

6.4

Comfort

7.2

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,294 reviews
American Airlines
7.2
Good
11,294 reviews

Overall

7.2

Boarding

7.5

Food

6.4

Comfort

7.2

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Milwaukee. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Milwaukee?

    A quick flight from Des Moines to Milwaukee can take about 4h 25m. Southwest provides one of the quickest options available for as low as $287. Des Moines and Milwaukee are separated by a distance of 310 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Des Moines to Milwaukee round-trip?

    Currently priced at $188, American Airlines will fly you from Des Moines to Milwaukee and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. American Airlines is currently priced 40% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Milwaukee that include hotel bookings?

    Yes. In addition to deals on Des Moines to Milwaukee flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Milwaukee?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Milwaukee.

  • Can I find deals for business class flights from Des Moines to Milwaukee?

    Yes. Cheapflights offers flight deals from Des Moines to Milwaukee by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Milwaukee?

    Currently, February is the cheapest month in which you can book a flight from Des Moines to Milwaukee (average of $142). Flying from Des Moines to Milwaukee in January is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Milwaukee?

Book flights to Milwaukee if you plan to visit one of these locations
Sheboygan
New Berlin
Oak Creek
Wauwatosa

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Des Moines to Milwaukee

Discover the top airline that operate flights from Des Moines to Milwaukee. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$188Average$267FlexibilityNo cancel feeOn-time71%

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