$173+ Cheap flights from Des Moines (DSM) to Mexico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/2. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Des Moines to Mexico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Mexico
Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated June 12, 2025.
Round-trip from | $316 (American Airlines) |
|---|---|
One-way from | $173 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $758 |
Find flight deals from Des Moines to Mexico
Cheapest flights from Des Moines to MexicoExplore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Aeromexico deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This FlightHub deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Mon 6/30
5:30 am-12:24 pm
1 stop8h 54m
San José del Cabo Los Cabos
Tue 7/8
10:25 am-6:39 pm
1 stop6h 14m
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Fri 7/11
6:30 am-11:20 am
1 stop28h 50m
Cancun
Fri 7/18
12:26 pm-5:16 pm
2 stops28h 50m
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Mon 10/20
5:45 am-11:30 am
1 stop7h 45m
San José del Cabo Los Cabos
Sat 10/25
6:01 am-10:23 pm
2 stops14h 22m
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Mon 11/24
2:14 pm-9:02 pm
1 stop5h 48m
Cancun
Wed 11/26
11:14 am-10:23 pm
2 stops12h 09m
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Wed 9/10
7:00 am-9:03 pm
2 stops14h 03m
Cancun
Thu 9/11
7:52 am-10:23 pm
2 stops14h 31m
Des MoinesMexico City
DSM - MEX
DSMMEX
Des Moines
Fri 7/11
2:00 pm-10:00 pm
3 stops33h 00m
Mexico City Benito Juarez
Fri 7/18
6:20 am-5:16 pm
2 stops33h 56m
Des MoinesGuadalajara
DSM - GDL
DSMGDL
Des Moines
Thu 7/17
3:44 pm-5:11 pm
1 stop26h 27m
Guadalajara Miguel Hidal
Fri 8/15
10:20 am-8:20 pm
1 stop9h 00m
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Mon 7/28
7:33 pm-4:20 pm
1 stop20h 47m
Cancun
Sun 8/3
3:25 pm-6:48 pm
1 stop27h 23m
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Wed 11/19
6:54 am-3:40 pm
1 stop7h 46m
Cancun
Tue 12/2
7:05 pm-11:57 am
1 stop17h 52m
Des MoinesPuerto Vallarta
DSM - PVR
DSMPVR
Des Moines
Sun 8/3
12:43 pm-12:24 pm
2 stops24h 41m
Puerto Vallarta Ordaz
Thu 8/7
9:29 am-10:36 pm
2 stops12h 07m
Best time to book a flight from Des Moines to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Mexico
What is the cheapest month to book a flight from Des Moines to Mexico?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $388). Flying from Des Moines to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to MX?
Find hourly flight availability from Des Moines to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Mexico as you normally would.
Rainfall in Mexico by month
Plan your trip to Mexico by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Mexico ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico when rainfall is around 0.0 in.
Temperature in Mexico by month
Plan your trip to Mexico by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Mexico, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).
Reviews of airlines servicing Mexico
Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated June 12, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and Aeromexico from Des Moines to Mexico to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
Entertainment
Boarding
Overall
Comfort
Crew
Reviews
John,May 2025
PVD - BNA
Food
Entertainment
Boarding
Overall
Comfort
Crew
Reviews
John,May 2025
PVD - BNA
Food
Entertainment
Boarding
Overall
Comfort
Crew
Reviews
John,May 2025
PVD - BNA
Food
Entertainment
Boarding
Overall
Comfort
Crew
Reviews
John,May 2025
PVD - BNA
Food
Entertainment
Boarding
Overall
Comfort
Crew
Reviews
John,May 2025
PVD - BNA
Food
Entertainment
Boarding
Overall
Comfort
Crew
Reviews
John,May 2025
PVD - BNA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Mexico
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from Des Moines to Mexico
Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$300 | Average$587 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$350 | Average$501 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$449 | Average$680 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$460 | Average$648 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$469 | Average$645 | FlexibilityNo cancel fee | On-time71% |