$206+ Cheap flights from Des Moines (DSM) to Mexico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Sep 27 — Oct 41
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Des Moines to Mexico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Mexico
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to MexicoExplore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 28, 2026.
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/239:31 pm -
2 stops34h 00m
Thu 12/39:42 am -
1 stop12h 44m
Deal found 8/24![Multiple Airlines logo]()
$454
This CheapOair deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
1 stop21h 00m
Mon 11/29:02 am -
1 stop10h 33m
Deal found 8/24![Frontier logo]()
$457
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:42 pm -
1 stop27h 07m
Tue 10/206:10 am -
2 stops30h 42m
Deal found 8/27![Multiple Airlines logo]()
$461
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:31 pm -
2 stops19h 34m
Tue 9/298:46 am -
1 stop28h 06m
Deal found 8/24![Multiple Airlines logo]()
$462
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:30 pm -
1 stop20h 58m
Fri 12/411:54 am -
1 stop8h 34m
Deal found 8/25![Multiple Airlines logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am -
2 stops33h 40m
Tue 10/2011:51 am -
1 stop25h 01m
Deal found 8/27![Multiple Airlines logo]()
$471
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:31 pm -
2 stops19h 34m
Thu 10/111:51 am -
1 stop22h 06m
Deal found 8/24![Multiple Airlines logo]()
$473
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:25 pm -
1 stop22h 05m
Mon 10/1910:53 pm -
2 stops37h 59m
Deal found 8/28![Multiple Airlines logo]()
$476
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:00 am -
2 stops12h 23m
Tue 9/298:46 am -
1 stop28h 06m
Deal found 8/24![Multiple Airlines logo]()
$478
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:31 pm -
2 stops19h 34m
Fri 9/2510:37 am -
1 stop8h 11m
Deal found 8/24![Multiple Airlines logo]()
$479
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:09 pm -
2 stops31h 47m
Thu 11/59:42 am -
1 stop9h 52m
Deal found 8/24![Multiple Airlines logo]()
$480
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:42 pm -
1 stop26h 35m
Wed 10/147:34 pm -
2 stops20h 18m
Deal found 8/23![Multiple Airlines logo]()
$484
Best flights from Des Moines to MexicoDiscover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 28, 2026.
Discover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:25 pm -
1 stop22h 05m
Mon 10/1910:53 pm -
2 stops37h 59m
Deal found 8/28![Multiple Airlines logo]()
$476
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:12 pm -
1 stop21h 27m
Thu 10/151:29 pm -
1 stop18h 46m
Deal found 8/24![American Airlines logo]()
$566
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:10 am -
2 stops13h 45m
Thu 11/196:04 am -
2 stops13h 03m
Deal found 8/23![Delta logo]()
$571
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:45 am -
1 stop8h 08m
Fri 10/912:19 pm -
1 stop8h 56m
Deal found 8/25![United Airlines logo]()
$591
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:00 am -
2 stops8h 50m
Sun 12/1311:50 am -
2 stops10h 10m
Deal found 8/26![Southwest logo]()
$626
This Justfly.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:30 pm -
2 stops24h 24m
Sun 11/19:45 am -
2 stops33h 50m
Deal found 8/25![Frontier logo]()
$633
This Aeromexico deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:45 am -
2 stops18h 19m
Sat 10/101:55 pm -
1 stop7h 38m
Deal found 8/24![Aeromexico logo]()
$667
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:42 pm -
1 stop26h 35m
Wed 10/147:34 pm -
2 stops20h 18m
Deal found 8/23![Multiple Airlines logo]()
$484
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:45 pm -
1 stop29h 20m
Mon 11/910:50 pm -
2 stops39h 05m
Deal found 8/23![Multiple Airlines logo]()
$527
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:30 am -
1 stop14h 25m
Fri 12/48:15 am -
1 stop15h 23m
Deal found 8/26![Delta logo]()
$592
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop5h 51m
Tue 10/2711:50 am -
1 stop9h 40m
Deal found 8/27![United Airlines logo]()
$598
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:14 am -
1 stop7h 00m
Tue 10/135:35 am -
1 stop8h 36m
Deal found 8/24![American Airlines logo]()
$598
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/215:55 am -
2 stops8h 30m
Mon 1/259:40 am -
2 stops12h 00m
Deal found 8/25![Southwest logo]()
$627
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:27 am -
1 stop8h 28m
Thu 11/58:00 am -
2 stops12h 14m
Deal found 8/26![Delta logo]()
$597
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:15 am -
1 stop6h 18m
Wed 9/3012:11 pm -
1 stop9h 16m
Deal found 8/23![United Airlines logo]()
$604
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:22 pm -
2 stops20h 02m
Fri 10/212:26 pm -
1 stop8h 46m
Deal found 8/28![American Airlines logo]()
$609
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:25 am -
2 stops13h 20m
Fri 12/48:20 am -
2 stops13h 25m
Deal found 8/26![Southwest logo]()
$628
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:45 am -
2 stops13h 10m
Thu 12/39:24 am -
2 stops14h 14m
Deal found 8/25![Delta logo]()
$597
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop6h 10m
Wed 10/141:55 pm -
1 stop8h 53m
Deal found 8/24![United Airlines logo]()
$615
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:42 pm -
1 stop16h 30m
Wed 10/1412:07 pm -
1 stop20h 08m
Deal found 8/23![American Airlines logo]()
$627
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Fri 1/88:00 am -
1 stop7h 32m
Fri 1/1512:49 pm -
1 stop8h 41m
Deal found 8/23![United Airlines logo]()
$621
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:51 am -
1 stop27h 27m
Sat 10/1011:29 am -
1 stop6h 31m
Deal found 8/26![American Airlines logo]()
$632
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:22 am -
2 stops12h 58m
Mon 10/198:35 am -
2 stops11h 25m
Deal found 8/28![Delta logo]()
$640
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:12 pm -
1 stop19h 07m
Wed 11/41:57 pm -
1 stop9h 02m
Deal found 8/23![United Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:26 pm -
1 stop17h 27m
Thu 12/172:18 pm -
1 stop8h 25m
Deal found 8/27![American Airlines logo]()
$647
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:20 am -
1 stop9h 24m
Sun 12/137:07 am -
1 stop10h 59m
Deal found 8/25![Delta logo]()
$662
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:01 pm -
1 stop9h 09m
Wed 11/112:40 pm -
1 stop7h 50m
Deal found 8/24![United Airlines logo]()
$635
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:09 am -
1 stop10h 46m
Mon 11/98:06 am -
1 stop15h 20m
Deal found 8/23![American Airlines logo]()
$665
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:10 pm -
2 stops18h 32m
Fri 10/1612:55 pm -
2 stops19h 47m
Deal found 8/27![Delta logo]()
$674
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:00 am -
1 stop6h 25m
Mon 11/95:40 am -
2 stops10h 27m
Deal found 8/23![United Airlines logo]()
$640
Last-minute flights from Des Moines to MexicoDiscover last-minute flight deals from Des Moines to Mexico. Data last updated August 28, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Mexico. Data last updated August 28, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:30 pm -
1 stop22h 00m
Mon 9/148:40 am -
1 stop9h 53m
Deal found 8/24![Multiple Airlines logo]()
$532
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:00 am -
2 stops12h 23m
Tue 9/298:46 am -
1 stop28h 06m
Deal found 8/24![Multiple Airlines logo]()
$478
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:00 am -
2 stops12h 23m
Thu 10/111:51 am -
1 stop22h 06m
Deal found 8/24![Multiple Airlines logo]()
$488
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:00 am -
2 stops12h 23m
Fri 9/2510:37 am -
1 stop8h 11m
Deal found 8/24![Multiple Airlines logo]()
$495
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:00 am -
2 stops12h 23m
Wed 9/307:58 am -
1 stop25h 46m
Deal found 8/24![Multiple Airlines logo]()
$504
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:31 pm -
2 stops19h 34m
Tue 9/298:46 am -
1 stop28h 06m
Deal found 8/24![Multiple Airlines logo]()
$462
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:31 pm -
2 stops19h 34m
Thu 10/111:51 am -
1 stop22h 06m
Deal found 8/24![Multiple Airlines logo]()
$473
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:31 pm -
2 stops19h 34m
Fri 9/2510:37 am -
1 stop8h 11m
Deal found 8/24![Multiple Airlines logo]()
$479
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:31 pm -
2 stops19h 34m
Wed 9/307:58 am -
1 stop25h 46m
Deal found 8/24![Multiple Airlines logo]()
$489
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:29 am -
1 stop29h 56m
Tue 9/296:10 am -
2 stops30h 42m
Deal found 8/24![Multiple Airlines logo]()
$486
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:31 pm -
1 stop22h 46m
Mon 9/288:22 pm -
2 stops40h 30m
Deal found 8/24![Multiple Airlines logo]()
$501
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:31 pm -
1 stop23h 23m
Sun 10/118:50 pm -
2 stops21h 40m
Deal found 8/24![Multiple Airlines logo]()
$493
One-way flights from Des Moines to MexicoSearch for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated August 28, 2026.
Search for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated August 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:00 am -
2 stops26h 35m
Deal found 8/24![Multiple Airlines logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:42 pm -
2 stops31h 48m
Deal found 8/23![Multiple Airlines logo]()
$215
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:00 am -
1 stop7h 34m
Deal found 8/26![American Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:42 pm -
3 stops46h 53m
Deal found 8/23![Multiple Airlines logo]()
$246
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:42 pm -
1 stop16h 10m
Deal found 8/24![American Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:25 pm -
3 stops37h 35m
Deal found 8/24![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:25 pm -
3 stops37h 38m
Deal found 8/24![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:42 pm -
2 stops52h 17m
Deal found 8/23![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:32 pm -
1 stop25h 22m
Deal found 8/23![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:56 pm -
3 stops35h 44m
Deal found 8/26![Multiple Airlines logo]()
$265
This Expedia deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/315:45 am -
2 stops27h 00m
Deal found 8/24![Aeromexico logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:00 am -
3 stops34h 35m
Deal found 8/27![Multiple Airlines logo]()
$271
Find flight deals from Des Moines to Mexico
Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated August 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $434 (Kiwi.com) |
One-way from | $206 (Kiwi.com) |
Popular in | December |
Cheapest in | March |
Average price | $628 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 28, 2026.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesMexico City
DSM Des Moines - MEX Mexico City Benito Juarez
DSMMEX
Des Moines
Mon 10/12
8:25 pm-5:30 pm
1 stop22h 05m
Mexico City Benito Juarez
Mon 10/19
10:53 pm-1:52 pm
2 stops37h 59m
$476
Des MoinesMonterrey
DSM Des Moines - MTY Monterrey Gen Mariano Escobedo
DSMMTY
Des Moines
Wed 10/7
2:42 pm-4:17 pm
1 stop26h 35m
Monterrey Gen Mariano Escobedo
Wed 10/14
7:34 pm-4:52 pm
2 stops20h 18m
$484
Des MoinesMexico City
DSM Des Moines - MEX Mexico City Benito Juarez
DSMMEX
Des Moines
Wed 11/4
2:45 pm-8:05 pm
1 stop29h 20m
Mexico City Benito Juarez
Mon 11/9
10:50 pm-1:55 pm
2 stops39h 05m
$527
Des MoinesMérida
DSM Des Moines - MID Mérida Rejon
DSMMID
Des Moines
Thu 10/8
4:12 pm-12:39 pm
1 stop21h 27m
Mérida Rejon
Thu 10/15
1:29 pm-9:15 am
1 stop18h 46m
$566
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Sun 11/15
6:10 am-8:55 pm
2 stops13h 45m
Cancun
Thu 11/19
6:04 am-6:07 pm
2 stops13h 03m
$571
Des MoinesPuerto Vallarta
DSM Des Moines - PVR Puerto Vallarta Ordaz
DSMPVR
Des Moines
Sun 10/4
5:45 am-12:53 pm
1 stop8h 08m
Puerto Vallarta Ordaz
Fri 10/9
12:19 pm-10:15 pm
1 stop8h 56m
$591
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Thu 11/26
5:30 am-8:55 pm
1 stop14h 25m
Cancun
Fri 12/4
8:15 am-10:38 pm
1 stop15h 23m
$592
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Thu 10/29
11:27 am-7:55 pm
1 stop8h 28m
Cancun
Thu 11/5
8:00 am-7:14 pm
2 stops12h 14m
$597
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Thu 11/26
6:45 am-8:55 pm
2 stops13h 10m
Cancun
Thu 12/3
9:24 am-10:38 pm
2 stops14h 14m
$597
Des MoinesLeón
DSM Des Moines - BJX León Del Bajio
DSMBJX
Des Moines
Tue 9/29
6:00 am-10:51 am
1 stop5h 51m
León Del Bajio
Tue 10/27
11:50 am-10:30 pm
1 stop9h 40m
$598
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
DSM-BJX
DSM-MEX
DSM-CUN
DSM-PVR
DSM-SJD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Mexico
DSM-MX0
DSM-BJX
DSM-MEX
DSM-CUN
DSM-PVR
What is the cheapest month to book a flight from Des Moines to Mexico?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $587). Flying from Des Moines to Mexico in December is currently the most expensive (average of $778). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Des Moines to Mexico?
Booking 16 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Mexico. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Mexico
Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated August 28, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Top regions
Alternative routes for Des Moines to Mexico
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Mexico by cabin class
Find flights from Des Moines to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Mexico flights
Browse other Des Moines and Mexico flight options. Last updated on August 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Des Moines to Mexico flights
Consider these flights traveling from Des Moines to Mexico.
Fly to Mexico regions
Consider these flights traveling to Mexico regions.
Top 5 airlines flying from Des Moines to Mexico
Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$494 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$437 | Average$679 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$459 | Average$718 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$465 | Average$749 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$569 | Average$697 | FlexibilityNo cancel fee | On-time63% |