$165+ Cheap flights from Des Moines (DSM) to Mexico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/3. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Jul 17 — Jul 241
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to MexicoExplore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2026.
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:31 pm
DSM
- MEX
1 stop27h 59m
Multiple Airlines
Tue 10/2711:00 am
MEX
- DSM
1 stop25h 52m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$439
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/269:56 pm
DSM
- MTY
1 stop22h 24m
Multiple Airlines
Tue 8/412:05 pm
MTY
- DSM
1 stop23h 54m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$461
This Priceline deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/242:19 pm
DSM
- CUN
1 stop22h 30m
Frontier
Thu 7/303:31 pm
CUN
- DSM
1 stop22h 03m
Frontier
Deal found 6/13![Frontier logo]()
$474
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:56 pm
DSM
- MEX
1 stop23h 09m
Multiple Airlines
Tue 10/611:00 am
MEX
- DSM
1 stop25h 52m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$477
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:56 pm
DSM
- MEX
1 stop23h 09m
Multiple Airlines
Wed 10/710:35 pm
MEX
- DSM
2 stops35h 22m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$478
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:06 pm
DSM
- GDL
2 stops26h 54m
Multiple Airlines
Sun 8/2311:51 am
GDL
- DSM
1 stop30h 57m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$491
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:31 pm
DSM
- MEX
1 stop27h 59m
Multiple Airlines
Tue 10/2711:55 am
MEX
- DSM
1 stop24h 57m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$493
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:01 pm
DSM
- GDL
1 stop22h 53m
Multiple Airlines
Mon 8/34:09 pm
GDL
- DSM
2 stops44h 25m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$495
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:51 pm
DSM
- MEX
1 stop27h 39m
Multiple Airlines
Sun 10/48:40 am
MEX
- DSM
2 stops12h 17m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$501
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:00 am
DSM
- MEX
2 stops37h 00m
Multiple Airlines
Sun 10/48:40 am
MEX
- DSM
2 stops12h 17m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$502
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:00 am
DSM
- MEX
2 stops24h 25m
Multiple Airlines
Tue 10/611:00 am
MEX
- DSM
1 stop25h 52m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$503
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:16 pm
DSM
- GDL
1 stop10h 54m
Multiple Airlines
Thu 7/166:10 am
GDL
- DSM
2 stops8h 57m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$512
Best flights from Des Moines to MexicoDiscover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 17, 2026.
Discover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:01 pm
DSM
- GDL
1 stop22h 53m
Multiple Airlines
Mon 8/34:09 pm
GDL
- DSM
2 stops44h 25m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$495
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:00 am
DSM
- CUN
1 stop7h 01m
Delta
Fri 8/1412:35 pm
CUN
- DSM
1 stop8h 04m
Delta
Deal found 6/13![Delta logo]()
$569
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:41 am
DSM
- PVR
1 stop25h 53m
American Airlines
Tue 8/411:38 am
PVR
- DSM
1 stop11h 20m
American Airlines
Deal found 6/13![American Airlines logo]()
$578
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:40 am
DSM
- CUN
2 stops8h 20m
Southwest
Fri 8/1411:35 am
CUN
- DSM
2 stops10h 35m
Southwest
Deal found 6/16![Southwest logo]()
$584
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:50 pm
DSM
- CZM
2 stops19h 52m
United Airlines
Fri 7/313:52 pm
CZM
- DSM
2 stops18h 25m
United Airlines
Deal found 6/13![United Airlines logo]()
$606
This Aeromexico deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:28 am
DSM
- MTY
2 stops21h 24m
Aeromexico
Tue 9/112:15 pm
MTY
- DSM
1 stop9h 22m
Aeromexico
Deal found 6/15![Aeromexico logo]()
$622
This Faresmojo deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:15 am
DSM
- GDL
1 stop6h 10m
JetBlue
Sat 8/296:40 am
GDL
- DSM
1 stop6h 34m
JetBlue
Deal found 6/16![JetBlue logo]()
$692
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:01 pm
DSM
- GDL
2 stops34h 29m
Multiple Airlines
Fri 7/248:46 am
GDL
- DSM
1 stop11h 25m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$556
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:25 pm
DSM
- CUN
1 stop5h 58m
Delta
Wed 8/512:35 pm
CUN
- DSM
1 stop8h 04m
Delta
Deal found 6/13![Delta logo]()
$594
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/14:48 pm
DSM
- SJD
2 stops17h 13m
American Airlines
Fri 8/71:13 pm
SJD
- DSM
2 stops17h 48m
American Airlines
Deal found 6/16![American Airlines logo]()
$600
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:00 am
DSM
- MID
2 stops11h 05m
United Airlines
Mon 7/207:00 am
MID
- DSM
1 stop14h 35m
United Airlines
Deal found 6/16![United Airlines logo]()
$623
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:10 am
DSM
- CUN
2 stops10h 35m
Southwest
Sat 8/110:45 am
CUN
- DSM
1 stop12h 10m
Southwest
Deal found 6/14![Southwest logo]()
$624
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:16 pm
DSM
- GDL
1 stop22h 59m
Multiple Airlines
Sat 10/248:46 am
GDL
- DSM
1 stop27h 21m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$569
This Aeromexico deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/305:40 am
DSM
- PVR
1 stop7h 48m
Aeromexico
Wed 9/21:39 pm
PVR
- DSM
1 stop7h 58m
Aeromexico
Deal found 6/12![Aeromexico logo]()
$634
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:40 am
DSM
- SJD
1 stop7h 27m
Delta
Wed 8/1912:12 pm
SJD
- DSM
1 stop8h 25m
Delta
Deal found 6/15![Delta logo]()
$596
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:32 am
DSM
- SJD
1 stop5h 53m
American Airlines
Wed 8/191:13 pm
SJD
- DSM
2 stops17h 48m
American Airlines
Deal found 6/13![American Airlines logo]()
$605
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:10 am
DSM
- CUN
2 stops10h 35m
Southwest
Sun 7/2611:15 am
CUN
- DSM
1 stop11h 20m
Southwest
Deal found 6/14![Southwest logo]()
$624
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:19 pm
DSM
- MTY
2 stops31h 04m
Multiple Airlines
Wed 8/511:20 am
MTY
- DSM
1 stop27h 58m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$571
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/273:26 pm
DSM
- MEX
2 stops8h 44m
United Airlines
Thu 8/276:30 am
MEX
- DSM
2 stops9h 58m
United Airlines
Deal found 6/13![United Airlines logo]()
$633
This Aeromexico deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:40 am
DSM
- PVR
1 stop7h 48m
Aeromexico
Wed 8/191:39 pm
PVR
- DSM
1 stop7h 58m
Aeromexico
Deal found 6/16![Aeromexico logo]()
$644
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:12 am
DSM
- MTY
1 stop7h 34m
American Airlines
Fri 7/244:42 pm
MTY
- DSM
1 stop6h 17m
American Airlines
Deal found 6/12![American Airlines logo]()
$606
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:10 am
DSM
- CUN
1 stop9h 15m
Southwest
Sun 7/1911:25 am
CUN
- DSM
1 stop12h 25m
Southwest
Deal found 6/16![Southwest logo]()
$629
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/196:20 am
DSM
- PVR
1 stop8h 36m
United Airlines
Fri 7/312:52 pm
PVR
- DSM
2 stops18h 25m
United Airlines
Deal found 6/16![United Airlines logo]()
$634
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:54 am
DSM
- MEX
2 stops12h 11m
Delta
Wed 8/55:50 pm
MEX
- DSM
2 stops15h 53m
Delta
Deal found 6/14![Delta logo]()
$640
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:47 am
DSM
- GDL
1 stop13h 13m
American Airlines
Fri 9/111:30 pm
GDL
- DSM
1 stop18h 47m
American Airlines
Deal found 6/16![American Airlines logo]()
$619
This Aeromexico deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:40 am
DSM
- PVR
2 stops29h 46m
Aeromexico
Sat 9/121:29 pm
PVR
- DSM
1 stop8h 00m
Aeromexico
Deal found 6/14![Aeromexico logo]()
$694
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:00 am
DSM
- MEX
2 stops10h 30m
Delta
Thu 8/65:50 pm
MEX
- DSM
2 stops15h 53m
Delta
Deal found 6/15![Delta logo]()
$640
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am
DSM
- GDL
1 stop6h 25m
United Airlines
Mon 10/56:40 am
GDL
- DSM
1 stop14h 35m
United Airlines
Deal found 6/12![United Airlines logo]()
$655
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:10 am
DSM
- SJD
2 stops10h 30m
Southwest
Mon 8/311:35 am
SJD
- DSM
2 stops10h 00m
Southwest
Deal found 6/12![Southwest logo]()
$664
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:19 pm
DSM
- MTY
1 stop28h 46m
Multiple Airlines
Fri 7/246:00 am
MTY
- DSM
2 stops14h 11m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$666
Last-minute flights from Des Moines to MexicoDiscover last-minute flight deals from Des Moines to Mexico. Data last updated June 17, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Mexico. Data last updated June 17, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/269:56 pm
DSM
- MTY
1 stop22h 24m
Multiple Airlines
Tue 8/412:05 pm
MTY
- DSM
1 stop23h 54m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$461
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/269:56 pm
DSM
- GDL
2 stops34h 22m
Multiple Airlines
Fri 7/1010:25 am
GDL
- DSM
1 stop9h 58m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$528
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:16 pm
DSM
- GDL
1 stop10h 54m
Multiple Airlines
Thu 7/166:10 am
GDL
- DSM
2 stops8h 57m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$512
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:16 pm
DSM
- GDL
1 stop10h 54m
Multiple Airlines
Tue 7/148:20 am
GDL
- DSM
2 stops28h 14m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$519
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:16 pm
DSM
- GDL
1 stop10h 54m
Multiple Airlines
Sun 7/128:20 am
GDL
- DSM
2 stops28h 14m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$525
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:01 pm
DSM
- GDL
1 stop19h 48m
Multiple Airlines
Mon 7/135:00 pm
GDL
- DSM
2 stops43h 34m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$522
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- MEX
1 stop24h 44m
Multiple Airlines
Mon 7/276:00 am
MEX
- DSM
2 stops53h 59m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$500
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- GDL
1 stop19h 48m
Multiple Airlines
Mon 7/277:10 am
GDL
- DSM
2 stops52h 49m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$521
This Priceline deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/242:19 pm
DSM
- CUN
1 stop22h 30m
Frontier
Thu 7/303:31 pm
CUN
- DSM
1 stop22h 03m
Frontier
Deal found 6/13![Frontier logo]()
$474
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:01 pm
DSM
- GDL
1 stop22h 53m
Multiple Airlines
Mon 8/34:09 pm
GDL
- DSM
2 stops44h 25m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$495
This lastminute.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:41 am
DSM
- CUN
1 stop7h 24m
Aeromexico
Tue 8/412:35 pm
CUN
- DSM
1 stop8h 04m
Aeromexico
Deal found 6/12![Aeromexico logo]()
$525
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/291:49 pm
DSM
- MEX
1 stop8h 56m
Multiple Airlines
Wed 8/58:45 pm
MEX
- DSM
2 stops23h 46m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$533
One-way flights from Des Moines to MexicoSearch for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated June 17, 2026.
Search for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated June 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:01 pm
DSM
- MTY
1 stop22h 19m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/299:56 pm
DSM
- MTY
1 stop22h 24m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/269:56 pm
DSM
- GDL
2 stops34h 22m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/129:33 pm
DSM
- GDL
1 stop20h 16m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:01 pm
DSM
- GDL
1 stop19h 48m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:16 pm
DSM
- MTY
2 stops32h 04m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:16 pm
DSM
- GDL
1 stop27h 09m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:16 pm
DSM
- MEX
1 stop28h 14m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:31 pm
DSM
- PVR
3 stops39h 53m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:19 pm
DSM
- GDL
1 stop27h 06m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/59:33 pm
DSM
- GDL
1 stop27h 25m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:01 pm
DSM
- GDL
1 stop19h 48m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$220
Find flight deals from Des Moines to Mexico
Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated June 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $439 (Kiwi.com) |
One-way from | $189 (Kiwi.com) |
Popular in | December |
Cheapest in | March |
Average price | $764 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesGuadalajara
DSM - GDL
DSMGDL
Des Moines
Mon 7/27
10:01 pm-7:54 pm
1 stop22h 53m
Guadalajara Miguel Hidal
Mon 8/3
4:09 pm-1:34 pm
2 stops44h 25m
$495
Des MoinesGuadalajara
DSM - GDL
DSMGDL
Des Moines
Fri 7/3
10:01 pm-7:30 am
2 stops34h 29m
Guadalajara Miguel Hidal
Fri 7/24
8:46 am-9:11 pm
1 stop11h 25m
$556
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Sun 8/9
6:00 am-1:01 pm
1 stop7h 01m
Cancun
Fri 8/14
12:35 pm-8:39 pm
1 stop8h 04m
$569
Des MoinesGuadalajara
DSM - GDL
DSMGDL
Des Moines
Thu 10/1
8:16 pm-6:15 pm
1 stop22h 59m
Guadalajara Miguel Hidal
Sat 10/24
8:46 am-1:07 pm
1 stop27h 21m
$569
Des MoinesMonterrey
DSM - MTY
DSMMTY
Des Moines
Wed 7/29
2:19 pm-8:23 pm
2 stops31h 04m
Monterrey Gen Mariano Escobedo
Wed 8/5
11:20 am-4:18 pm
1 stop27h 58m
$571
Des MoinesPuerto Vallarta
DSM - PVR
DSMPVR
Des Moines
Tue 7/28
9:41 am-10:34 am
1 stop25h 53m
Puerto Vallarta Ordaz
Tue 8/4
11:38 am-11:58 pm
1 stop11h 20m
$578
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Sun 8/9
5:40 am-2:00 pm
2 stops8h 20m
Cancun
Fri 8/14
11:35 am-10:10 pm
2 stops10h 35m
$584
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Wed 7/29
2:25 pm-8:23 pm
1 stop5h 58m
Cancun
Wed 8/5
12:35 pm-8:39 pm
1 stop8h 04m
$594
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Wed 8/12
5:40 am-11:07 am
1 stop7h 27m
San José del Cabo Los Cabos
Wed 8/19
12:12 pm-10:37 pm
1 stop8h 25m
$596
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Sat 8/1
4:48 pm-8:01 am
2 stops17h 13m
San José del Cabo Los Cabos
Fri 8/7
1:13 pm-9:01 am
2 stops17h 48m
$600
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
DSM-MTY
DSM-CUN
DSM-SJD
DSM-MEX
DSM-GDL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Mexico
DSM-MX0
DSM-MTY
DSM-CUN
DSM-SJD
DSM-MEX
What is the cheapest month to book a flight from Des Moines to Mexico?
Currently, June is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $206). Flying from Des Moines to Mexico in May is currently the most expensive (average of $450). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Des Moines to Mexico?
Booking 19 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Mexico. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Mexico
Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated June 17, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Des Moines and Mexico flights
Browse other Des Moines and Mexico flight options. Last updated on June 17, 2026.
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Des Moines to Mexico flights
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Top 5 airlines flying from Des Moines to Mexico
Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$494 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$366 | Average$690 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$379 | Average$669 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$397 | Average$639 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$569 | Average$697 | FlexibilityNo cancel fee | On-time63% |