$145+ Cheap flights from Des Moines (DSM) to Mexico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Aug 12 — Aug 191
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to MexicoExplore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:19 pm
DSM
- GDL
1 stop27h 06m
Multiple Airlines
Sun 9/206:00 am
GDL
- DSM
2 stops30h 56m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm
DSM
- GDL
1 stop19h 59m
Multiple Airlines
Sun 8/306:00 am
GDL
- DSM
2 stops30h 34m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$405
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:19 pm
DSM
- GDL
1 stop27h 06m
Multiple Airlines
Wed 9/166:52 pm
GDL
- DSM
2 stops24h 05m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:19 pm
DSM
- GDL
1 stop27h 06m
Multiple Airlines
Sun 9/206:00 am
GDL
- DSM
2 stops30h 56m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$417
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:00 am
DSM
- MTY
1 stop8h 10m
Multiple Airlines
Sun 8/3011:30 am
MTY
- DSM
2 stops25h 04m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$430
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm
DSM
- MEX
2 stops20h 40m
Multiple Airlines
Sun 8/308:40 am
MEX
- DSM
1 stop27h 54m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
- GDL
2 stops40h 34m
Multiple Airlines
Mon 8/1710:25 am
GDL
- DSM
1 stop9h 51m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:06 pm
DSM
- GDL
1 stop19h 43m
Multiple Airlines
Mon 8/2410:25 am
GDL
- DSM
1 stop8h 23m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$436
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:31 pm
DSM
- MEX
1 stop27h 59m
Multiple Airlines
Tue 10/2712:05 pm
MEX
- DSM
1 stop24h 47m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$440
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:01 pm
DSM
- GDL
1 stop19h 48m
Multiple Airlines
Tue 8/118:25 am
GDL
- DSM
2 stops28h 09m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$443
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:51 pm
DSM
- MEX
1 stop26h 09m
Multiple Airlines
Wed 12/210:35 pm
MEX
- DSM
2 stops23h 51m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$446
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:19 pm
DSM
- GDL
1 stop27h 06m
Multiple Airlines
Thu 9/1710:37 am
GDL
- DSM
1 stop9h 29m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$446
Best flights from Des Moines to MexicoDiscover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
Discover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:44 pm
DSM
- CUN
2 stops36h 19m
Multiple Airlines
Thu 8/131:59 pm
CUN
- DSM
1 stop28h 16m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:45 am
DSM
- SJD
1 stop8h 20m
United Airlines
Thu 8/271:17 pm
SJD
- DSM
1 stop8h 27m
United Airlines
Deal found 7/13![United Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:35 pm
DSM
- MID
1 stop18h 37m
American Airlines
Thu 8/271:52 pm
MID
- DSM
1 stop24h 20m
American Airlines
Deal found 7/8![American Airlines logo]()
$562
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:45 am
DSM
- CUN
1 stop8h 25m
Delta
Tue 9/2912:35 pm
CUN
- DSM
1 stop9h 54m
Delta
Deal found 7/12![Delta logo]()
$568
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:00 am
DSM
- CUN
1 stop9h 00m
Southwest
Sat 10/31:30 pm
CUN
- DSM
1 stop7h 15m
Southwest
Deal found 7/11![Southwest logo]()
$568
This Rumbo deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:54 pm
DSM
- BJX
2 stops18h 21m
Aeromexico
Thu 9/39:00 am
BJX
- DSM
1 stop12h 37m
Aeromexico
Deal found 7/12![Aeromexico logo]()
$572
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/201:37 pm
DSM
- MEX
1 stop9h 38m
Multiple Airlines
Mon 7/276:20 am
MEX
- DSM
1 stop11h 44m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$492
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:13 pm
DSM
- MID
1 stop21h 59m
American Airlines
Thu 9/31:52 pm
MID
- DSM
1 stop27h 00m
American Airlines
Deal found 7/13![American Airlines logo]()
$564
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:55 am
DSM
- CUN
2 stops13h 10m
Delta
Wed 8/198:05 am
CUN
- DSM
2 stops12h 34m
Delta
Deal found 7/12![Delta logo]()
$572
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:15 am
DSM
- CZM
1 stop8h 27m
United Airlines
Fri 8/283:52 pm
CZM
- DSM
1 stop6h 38m
United Airlines
Deal found 7/8![United Airlines logo]()
$590
This Aeromexico deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:40 am
DSM
- SJD
1 stop7h 27m
Aeromexico
Fri 9/412:12 pm
SJD
- DSM
1 stop8h 25m
Aeromexico
Deal found 7/9![Aeromexico logo]()
$596
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:55 pm
DSM
- MTY
2 stops29h 55m
Multiple Airlines
Thu 8/2712:05 pm
MTY
- DSM
1 stop7h 55m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$573
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:22 pm
DSM
- MTY
1 stop22h 16m
American Airlines
Mon 8/314:28 pm
MTY
- DSM
1 stop5h 57m
American Airlines
Deal found 7/10![American Airlines logo]()
$583
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:15 am
DSM
- CZM
1 stop8h 27m
United Airlines
Mon 8/313:52 pm
CZM
- DSM
1 stop6h 38m
United Airlines
Deal found 7/11![United Airlines logo]()
$590
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:55 am
DSM
- CUN
2 stops13h 30m
Delta
Thu 9/39:11 am
CUN
- DSM
2 stops13h 26m
Delta
Deal found 7/13![Delta logo]()
$594
This Aeromexico deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:45 am
DSM
- SJD
2 stops18h 42m
Aeromexico
Fri 10/29:14 am
SJD
- DSM
2 stops11h 15m
Aeromexico
Deal found 7/10![Aeromexico logo]()
$596
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:15 am
DSM
- CUN
1 stop6h 18m
United Airlines
Sat 8/292:49 pm
CUN
- DSM
1 stop7h 41m
United Airlines
Deal found 7/10![United Airlines logo]()
$594
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:45 am
DSM
- SJD
2 stops13h 40m
Delta
Fri 10/212:12 pm
SJD
- DSM
1 stop8h 17m
Delta
Deal found 7/9![Delta logo]()
$596
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:41 am
DSM
- SJD
1 stop8h 30m
American Airlines
Fri 10/210:51 am
SJD
- DSM
1 stop10h 22m
American Airlines
Deal found 7/12![American Airlines logo]()
$596
This Aeromexico deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/115:40 am
DSM
- SJD
2 stops18h 47m
Aeromexico
Fri 10/166:15 am
SJD
- DSM
2 stops14h 19m
Aeromexico
Deal found 7/10![Aeromexico logo]()
$596
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/242:19 pm
DSM
- GDL
1 stop10h 51m
Multiple Airlines
Sun 8/95:50 am
GDL
- DSM
2 stops30h 44m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$604
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:45 am
DSM
- SJD
1 stop7h 22m
Delta
Tue 9/226:15 am
SJD
- DSM
2 stops14h 14m
Delta
Deal found 7/8![Delta logo]()
$596
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:33 am
DSM
- MID
1 stop7h 39m
American Airlines
Mon 8/311:52 pm
MID
- DSM
1 stop27h 00m
American Airlines
Deal found 7/9![American Airlines logo]()
$600
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/235:45 am
DSM
- SJD
1 stop8h 20m
United Airlines
Sun 8/301:17 pm
SJD
- DSM
1 stop8h 27m
United Airlines
Deal found 7/11![United Airlines logo]()
$614
This Aeromexico deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:45 am
DSM
- SJD
2 stops28h 42m
Aeromexico
Mon 10/56:15 am
SJD
- DSM
2 stops14h 14m
Aeromexico
Deal found 7/13![Aeromexico logo]()
$641
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:33 pm
DSM
- MEX
1 stop25h 12m
Multiple Airlines
Mon 8/107:00 am
MEX
- DSM
2 stops15h 14m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$648
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/244:13 pm
DSM
- PVR
2 stops22h 50m
American Airlines
Mon 8/311:19 pm
PVR
- DSM
1 stop24h 53m
American Airlines
Deal found 7/10![American Airlines logo]()
$611
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:55 am
DSM
- MID
2 stops12h 14m
Delta
Tue 9/15:47 am
MID
- DSM
2 stops15h 50m
Delta
Deal found 7/11![Delta logo]()
$619
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:15 am
DSM
- MID
1 stop12h 50m
United Airlines
Wed 9/27:00 am
MID
- DSM
1 stop6h 14m
United Airlines
Deal found 7/12![United Airlines logo]()
$619
This Aeromexico deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:54 pm
DSM
- MTY
2 stops18h 56m
Aeromexico
Mon 8/317:45 pm
MTY
- DSM
2 stops18h 31m
Aeromexico
Deal found 7/10![Aeromexico logo]()
$642
Last-minute flights from Des Moines to MexicoDiscover last-minute flight deals from Des Moines to Mexico. Data last updated July 13, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Mexico. Data last updated July 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:01 pm
DSM
- GDL
1 stop19h 48m
Multiple Airlines
Tue 8/118:25 am
GDL
- DSM
2 stops28h 09m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$443
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:01 pm
DSM
- GDL
1 stop19h 48m
Multiple Airlines
Mon 8/1710:25 am
GDL
- DSM
1 stop9h 51m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$448
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:01 pm
DSM
- GDL
1 stop19h 48m
Multiple Airlines
Thu 8/207:58 am
GDL
- DSM
1 stop28h 36m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$453
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:01 pm
DSM
- GDL
1 stop19h 48m
Multiple Airlines
Sat 8/225:00 pm
GDL
- DSM
2 stops27h 00m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$463
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:44 pm
DSM
- CUN
2 stops36h 19m
Multiple Airlines
Thu 8/131:59 pm
CUN
- DSM
1 stop28h 16m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$457
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
- GDL
2 stops40h 34m
Multiple Airlines
Mon 8/1710:25 am
GDL
- DSM
1 stop9h 51m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
- CUN
2 stops36h 42m
Multiple Airlines
Thu 8/131:59 pm
CUN
- DSM
1 stop28h 16m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$462
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:06 pm
DSM
- GDL
1 stop19h 43m
Multiple Airlines
Mon 8/2410:25 am
GDL
- DSM
1 stop8h 23m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$436
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:06 pm
DSM
- MEX
1 stop22h 59m
Multiple Airlines
Mon 8/245:35 am
MEX
- DSM
2 stops13h 13m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$455
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm
DSM
- GDL
1 stop19h 59m
Multiple Airlines
Sun 8/306:00 am
GDL
- DSM
2 stops30h 34m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$405
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/238:00 am
DSM
- MTY
1 stop8h 10m
Multiple Airlines
Sun 8/3011:30 am
MTY
- DSM
2 stops25h 04m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$430
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm
DSM
- MEX
2 stops20h 40m
Multiple Airlines
Sun 8/308:40 am
MEX
- DSM
1 stop27h 54m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$435
One-way flights from Des Moines to MexicoSearch for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
Search for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:19 pm
DSM
- GDL
1 stop10h 51m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:00 am
DSM
- MEX
2 stops13h 25m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:19 pm
DSM
- CUN
2 stops33h 39m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/231:55 pm
DSM
- MEX
2 stops45h 50m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm
DSM
- PVR
3 stops39h 45m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
- BJX
2 stops37h 09m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:01 pm
DSM
- GDL
2 stops34h 29m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:01 pm
DSM
- GDL
1 stop19h 48m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:41 pm
DSM
- MTY
3 stops49h 44m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:00 am
DSM
- GDL
1 stop20h 53m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:06 pm
DSM
- MEX
2 stops34h 19m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:01 pm
DSM
- GDL
1 stop26h 57m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$226
Find flight deals from Des Moines to Mexico
Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated July 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $378 (Kiwi.com) |
One-way from | $145 (Kiwi.com) |
Popular in | December |
Cheapest in | March |
Average price | $751 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Thu 8/6
9:44 pm-10:03 am
2 stops36h 19m
Cancun
Thu 8/13
1:59 pm-6:15 pm
1 stop28h 16m
$457
Des MoinesMexico City
DSM - MEX
DSMMEX
Des Moines
Mon 7/20
1:37 pm-10:15 pm
1 stop9h 38m
Mexico City Benito Juarez
Mon 7/27
6:20 am-7:04 pm
1 stop11h 44m
$492
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Sun 8/16
5:45 am-12:05 pm
1 stop8h 20m
San José del Cabo Los Cabos
Thu 8/27
1:17 pm-11:44 pm
1 stop8h 27m
$542
Des MoinesMérida
DSM - MID
DSMMID
Des Moines
Thu 8/20
7:35 pm-1:12 pm
1 stop18h 37m
Mérida Rejon
Thu 8/27
1:52 pm-3:12 pm
1 stop24h 20m
$562
Des MoinesMérida
DSM - MID
DSMMID
Des Moines
Thu 8/27
4:13 pm-1:12 pm
1 stop21h 59m
Mérida Rejon
Thu 9/3
1:52 pm-5:52 pm
1 stop27h 00m
$564
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Fri 9/25
5:45 am-2:10 pm
1 stop8h 25m
Cancun
Tue 9/29
12:35 pm-10:29 pm
1 stop9h 54m
$568
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Mon 9/28
7:00 am-4:00 pm
1 stop9h 00m
Cancun
Sat 10/3
1:30 pm-8:45 pm
1 stop7h 15m
$568
Des MoinesLeón
DSM - BJX
DSMBJX
Des Moines
Thu 8/27
2:54 pm-8:15 am
2 stops18h 21m
León Del Bajio
Thu 9/3
9:00 am-10:37 pm
1 stop12h 37m
$572
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Fri 8/14
6:55 am-8:05 pm
2 stops13h 10m
Cancun
Wed 8/19
8:05 am-8:39 pm
2 stops12h 34m
$572
Des MoinesMonterrey
DSM - MTY
DSMMTY
Des Moines
Thu 8/20
1:55 pm-6:50 pm
2 stops29h 55m
Monterrey Gen Mariano Escobedo
Thu 8/27
12:05 pm-9:00 pm
1 stop7h 55m
$573
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
DSM-GDL
DSM-MTY
DSM-MEX
DSM-CUN
DSM-SJD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Mexico
DSM-MX0
DSM-GDL
DSM-MTY
DSM-MEX
DSM-CUN
What is the cheapest month to book a flight from Des Moines to Mexico?
Currently, June is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $206). Flying from Des Moines to Mexico in May is currently the most expensive (average of $450). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Des Moines to Mexico?
Booking 10 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Mexico. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Mexico
Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated July 13, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Mexico
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Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Des Moines to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Mexico flights
Browse other Des Moines and Mexico flight options. Last updated on July 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Des Moines to Mexico flights
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Consider these flights traveling to Mexico regions.
Top 5 airlines flying from Des Moines to Mexico
Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$494 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$411 | Average$702 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$423 | Average$678 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$451 | Average$660 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$569 | Average$788 | FlexibilityNo cancel fee | On-time63% |