How long is the flight from Des Moines to Mexico?

Frontier, Delta, and American Airlines can get you from Des Moines to Mexico in just under 6h 36m. Your travel time can differ by up to 10h 34m. Airlines will cover a distance of 1470 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Mexico ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mexico, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular routes from Des Moines to Mexico?

Most travelers choose Des Moines - Cancun, Des Moines - Cozumel or Des Moines - Puerto Vallarta Ordaz when deciding on the best route from Des Moines to Mexico.

What are the most popular airlines that fly from Des Moines to Mexico?

The most popular airlines flying from Des Moines to Mexico are American Airlines, Delta and United Airlines. Something to consider prior to booking your flight.

What airport do you fly from for flights from Des Moines to Mexico?

Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

Can I find deals for flights from Des Moines to Mexico that include hotel bookings?

Yes. In addition to deals on Des Moines to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Mexico?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico.

Can I find deals for business class flights from Des Moines to Mexico?

Yes. Cheapflights offers flight deals from Des Moines to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$154+ Flights from Des Moines to Mexico

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Cheap flight deals from Des Moines to Mexico

Cheapest flights from Des Moines to Mexico
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 25, 2025.

Sun 12/286:59 amDSM - MEX

2 stops13h 06mDelta

Thu 1/156:40 amMEX - DSM

2 stops14h 14mDelta

Deal found 12/24

$608

Tue 12/302:35 pmDSM - CUN

1 stop25h 37mMultiple Airlines

Tue 1/62:36 pmCUN - DSM

2 stops27h 48mMultiple Airlines

Deal found 12/23

$612

Tue 12/306:15 amDSM - CUN

1 stop8h 50mDelta

Tue 1/61:45 pmCUN - DSM

1 stop8h 39mDelta

Deal found 12/23

$622

Sun 12/287:30 pmDSM - CUN

1 stop17h 01mMultiple Airlines

Tue 12/302:36 pmCUN - DSM

1 stop9h 34mMultiple Airlines

Deal found 12/24

$652

Tue 12/306:52 pmDSM - PVR

1 stop17h 36mAmerican Airlines

Tue 1/64:50 pmPVR - DSM

1 stop27h 14mAmerican Airlines

Deal found 12/23

$665

Fri 12/267:16 pmDSM - CUN

2 stops41h 16mMultiple Airlines

Tue 12/302:36 pmCUN - DSM

1 stop9h 34mMultiple Airlines

Deal found 12/24

$674

Sun 12/285:39 pmDSM - MEX

1 stop17h 51mAmerican Airlines

Thu 1/158:00 amMEX - DSM

1 stop9h 06mAmerican Airlines

Deal found 12/24

$678

Sun 12/283:14 pmDSM - MEX

2 stops18h 51mUnited Airlines

Thu 1/159:05 amMEX - DSM

1 stop14h 39mUnited Airlines

Deal found 12/24

$684

Sun 12/286:59 amDSM - CUN

1 stop6h 11mDelta

Fri 1/21:10 pmCUN - DSM

1 stop7h 52mDelta

Deal found 12/25

$712

Sun 12/286:59 amDSM - CUN

1 stop7h 21mDelta

Wed 12/314:30 pmCUN - DSM

2 stops19h 58mDelta

Deal found 12/24

$716

Fri 12/265:55 pmDSM - CUN

1 stop17h 15mDelta

Wed 12/312:56 pmCUN - DSM

1 stop6h 49mDelta

Deal found 12/24

$717

Thu 12/2512:10 pmDSM - CUN

2 stops21h 05mDelta

Wed 12/314:30 pmCUN - DSM

2 stops19h 58mDelta

Deal found 12/24

$721

Best flights from Des Moines to Mexico
Discover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 25, 2025.

Thu 2/54:30 pmDSM - MEX

2 stops28h 20mMultiple Airlines

Thu 2/128:10 amMEX - DSM

1 stop10h 37mMultiple Airlines

Deal found 12/24

$374

Sun 3/17:27 pmDSM - CUN

2 stops17h 10mFrontier

Mon 3/910:10 amCUN - DSM

2 stops23h 35mFrontier

Deal found 12/25

$425

Sun 1/256:24 amDSM - CUN

1 stop6h 36mDelta

Fri 1/308:00 amCUN - DSM

1 stop9h 28mDelta

Deal found 12/25

$435

Sun 2/85:05 amDSM - CUN

1 stop10h 03mAmerican Airlines

Fri 2/135:08 pmCUN - DSM

1 stop7h 30mAmerican Airlines

Deal found 12/25

$435

Sun 1/255:35 amDSM - CZM

1 stop8h 15mAeromexico

Fri 1/303:05 pmCZM - DSM

1 stop7h 24mAeromexico

Deal found 12/25

$447

Thu 2/58:10 amDSM - MLM

1 stop11h 12mUnited Airlines

Thu 2/128:00 amMLM - DSM

1 stop14h 20mUnited Airlines

Deal found 12/23

$539

Thu 2/127:32 pmDSM - MEX

1 stop21h 33mMultiple Airlines

Thu 2/269:05 amMEX - DSM

1 stop9h 37mMultiple Airlines

Deal found 12/22

$380

Tue 2/36:24 amDSM - CUN

2 stops13h 47mDelta

Tue 2/108:00 amCUN - DSM

2 stops14h 24mDelta

Deal found 12/24

$440

Mon 3/25:24 amDSM - CUN

1 stop10h 21mAeromexico

Thu 3/511:00 amCUN - DSM

1 stop6h 27mAeromexico

Deal found 12/25

$465

Wed 2/186:19 amDSM - CUN

2 stops13h 52mDelta

Wed 2/258:00 amCUN - DSM

1 stop9h 27mDelta

Deal found 12/25

$440

Thu 2/54:30 pmDSM - MTY

1 stop22h 25mMultiple Airlines

Thu 2/1211:00 amMTY - DSM

1 stop7h 47mMultiple Airlines

Deal found 12/24

$441

Thu 2/127:32 pmDSM - MEX

2 stops26h 28mFrontier

Thu 2/267:00 amMEX - DSM

2 stops11h 42mFrontier

Deal found 12/25

$486

Thu 2/54:25 pmDSM - MEX

1 stop20h 20mAmerican Airlines

Thu 2/126:00 amMEX - DSM

1 stop17h 38mAmerican Airlines

Deal found 12/23

$492

Tue 3/35:00 amDSM - SJD

1 stop11h 33mAmerican Airlines

Fri 3/64:35 pmSJD - DSM

1 stop6h 24mAmerican Airlines

Deal found 12/23

$494

Tue 2/177:52 amDSM - MLM

1 stop11h 30mUnited Airlines

Thu 3/127:00 amMLM - DSM

1 stop14h 44mUnited Airlines

Deal found 12/24

$552

Mon 1/126:30 amDSM - MEX

2 stops39h 30mMultiple Airlines

Mon 1/198:10 amMEX - DSM

1 stop11h 13mMultiple Airlines

Deal found 12/24

$466

Sun 2/86:24 amDSM - CUN

1 stop6h 36mDelta

Fri 2/138:00 amCUN - DSM

2 stops9h 57mDelta

Deal found 12/24

$469

Sun 1/256:54 amDSM - BJX

2 stops14h 07mAeromexico

Tue 2/37:44 amBJX - DSM

2 stops14h 45mAeromexico

Deal found 12/25

$550

Thu 2/55:51 pmDSM - GDL

1 stop6h 08mAmerican Airlines

Thu 2/122:18 pmGDL - DSM

1 stop20h 29mAmerican Airlines

Deal found 12/23

$507

Sat 2/215:03 pmDSM - CZM

2 stops20h 20mUnited Airlines

Wed 2/252:25 pmCZM - DSM

1 stop7h 55mUnited Airlines

Deal found 12/23

$562

Sun 2/84:30 pmDSM - MTY

1 stop22h 25mMultiple Airlines

Sun 2/1511:20 amMTY - DSM

2 stops31h 12mMultiple Airlines

Deal found 12/25

$472

Tue 3/36:50 amDSM - SJD

2 stops11h 47mDelta

Fri 3/611:46 amSJD - DSM

1 stop8h 34mDelta

Deal found 12/22

$494

Tue 2/311:26 amDSM - MTY

2 stops22h 41mAeromexico

Tue 2/1011:43 amMTY - DSM

2 stops10h 46mAeromexico

Deal found 12/23

$557

Fri 2/64:00 pmDSM - GDL

1 stop7h 59mAmerican Airlines

Fri 2/132:18 pmGDL - DSM

1 stop20h 25mAmerican Airlines

Deal found 12/23

$507

Wed 2/46:48 pmDSM - CZM

2 stops18h 35mUnited Airlines

Tue 2/102:25 pmCZM - DSM

2 stops9h 19mUnited Airlines

Deal found 12/24

$562

Fri 2/62:08 pmDSM - MEX

2 stops44h 37mMultiple Airlines

Fri 2/138:10 amMEX - DSM

1 stop10h 09mMultiple Airlines

Deal found 12/23

$482

Tue 3/1011:33 amDSM - SJD

2 stops22h 12mDelta

Wed 3/252:19 pmSJD - DSM

2 stops17h 27mDelta

Deal found 12/23

$499

Sun 2/85:35 amDSM - SJD

2 stops13h 02mAeromexico

Wed 2/116:25 pmSJD - DSM

2 stops27h 03mAeromexico

Deal found 12/24

$562

Sun 2/86:48 pmDSM - CZM

2 stops18h 35mUnited Airlines

Fri 2/132:25 pmCZM - DSM

1 stop7h 55mUnited Airlines

Deal found 12/23

$562

Fri 2/64:00 pmDSM - MTY

1 stop22h 49mAmerican Airlines

Fri 2/136:16 pmMTY - DSM

1 stop16h 27mAmerican Airlines

Deal found 12/23

$521

Last-minute flights from Des Moines to Mexico
Discover last-minute flight deals from Des Moines to Mexico. Data last updated December 25, 2025 and is based on user searches.

Mon 1/126:30 amDSM - MEX

2 stops39h 30mMultiple Airlines

Mon 1/198:10 amMEX - DSM

1 stop11h 13mMultiple Airlines

Deal found 12/24

$466

Mon 1/126:54 amDSM - CZM

1 stop8h 06mAeromexico

Thu 1/293:05 pmCZM - DSM

1 stop7h 24mAeromexico

Deal found 12/25

$527

Mon 1/126:54 amDSM - CZM

1 stop8h 06mDelta

Sun 1/183:05 pmCZM - DSM

1 stop7h 24mDelta

Deal found 12/25

$572

Thu 1/158:00 amDSM - GDL

2 stops14h 35mUnited Airlines

Tue 1/201:35 pmGDL - DSM

1 stop8h 55mUnited Airlines

Deal found 12/23

$563

Fri 1/168:18 pmDSM - GDL

1 stop24h 22mMultiple Airlines

Wed 1/282:34 pmGDL - DSM

2 stops32h 12mMultiple Airlines

Deal found 12/22

$495

Sun 1/185:35 amDSM - CZM

1 stop8h 15mAeromexico

Sun 1/253:05 pmCZM - DSM

1 stop7h 24mAeromexico

Deal found 12/24

$532

Mon 1/195:35 amDSM - CZM

1 stop8h 15mAeromexico

Tue 1/203:05 pmCZM - DSM

1 stop7h 24mAeromexico

Deal found 12/25

$561

Fri 1/235:35 amDSM - CZM

1 stop8h 15mAeromexico

Fri 1/303:05 pmCZM - DSM

1 stop7h 24mAeromexico

Deal found 12/24

$492

Sat 1/247:50 amDSM - CZM

2 stops29h 33mUnited Airlines

Wed 1/282:25 pmCZM - DSM

1 stop8h 05mUnited Airlines

Deal found 12/24

$562

Sun 1/255:35 amDSM - CZM

1 stop8h 15mAeromexico

Fri 1/303:05 pmCZM - DSM

1 stop7h 24mAeromexico

Deal found 12/25

$447

Sun 1/256:54 amDSM - BJX

2 stops14h 07mAeromexico

Tue 2/37:44 amBJX - DSM

2 stops14h 45mAeromexico

Deal found 12/25

$550

Sun 1/255:21 amDSM - BJX

1 stop18h 35mAmerican Airlines

Tue 2/36:00 amBJX - DSM

1 stop17h 23mAmerican Airlines

Deal found 12/25

$567

One-way flights from Des Moines to Mexico
Search for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated December 25, 2025.

Mon 2/96:07 amDSM - CUN

1 stop7h 43mAmerican Airlines

Deal found 12/24

$154

Mon 1/268:30 amDSM - MEX

1 stop12h 40mMultiple Airlines

Deal found 12/24

$170

Mon 2/911:09 amDSM - CUN

2 stops24h 07mMultiple Airlines

Deal found 12/24

$192

Sun 1/255:35 amDSM - CUN

2 stops12h 12mDelta

Deal found 12/25

$207

Mon 2/237:17 pmDSM - PVR

3 stops36h 48mMultiple Airlines

Deal found 12/24

$214

Sat 3/286:49 pmDSM - CUN

2 stops15h 17mUnited Airlines

Deal found 12/25

$222

Sat 3/286:56 pmDSM - CUN

1 stop13h 05mFrontier

Deal found 12/24

$224

Sat 3/287:27 pmDSM - CUN

1 stop15h 44mAmerican Airlines

Deal found 12/25

$236

Tue 2/175:24 amDSM - SJD

2 stops13h 13mDelta

Deal found 12/25

$261

Mon 2/236:50 amDSM - PVR

1 stop7h 10mDelta

Deal found 12/24

$261

Mon 2/233:24 pmDSM - CUN

2 stops19h 01mUnited Airlines

Deal found 12/24

$262

Sat 2/74:00 pmDSM - SJD

1 stop19h 55mAmerican Airlines

Deal found 12/24

$268

Find flight deals from Des Moines to Mexico

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$353 (Mytrip)
One-way from	$154 (American Airlines)
Popular in	December
Cheapest in	August
Average price	$948

Provider with most accurate pricing for Des Moines-Mexico City Benito Juarez flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Mexico City Benito Juarez flights.

Search Deals

From Des Moines to Mexico

Search Deals

One-way flight from Des Moines to Mexico

Search Deals

Highest demand for flights based on searches. 22% potential increase in price ($181 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 2/5

4:30 pm-8:50 pm

2 stops28h 20m

Mexico City Benito Juarez

Thu 2/12

8:10 am-6:47 pm

1 stop10h 37m

$374

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 2/12

7:32 pm-5:05 pm

1 stop21h 33m

Mexico City Benito Juarez

Thu 2/26

9:05 am-6:42 pm

1 stop9h 37m

$380

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sun 3/1

7:27 pm-1:37 pm

2 stops17h 10m

Cancun

Mon 3/9

10:10 am-9:45 am

2 stops23h 35m

$425

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sun 1/25

6:24 am-2:00 pm

1 stop6h 36m

Cancun

Fri 1/30

8:00 am-4:28 pm

1 stop9h 28m

$435

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sun 2/8

5:05 am-4:08 pm

1 stop10h 03m

Cancun

Fri 2/13

5:08 pm-11:38 pm

1 stop7h 30m

$435

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 2/3

6:24 am-9:11 pm

2 stops13h 47m

Cancun

Tue 2/10

8:00 am-9:24 pm

2 stops14h 24m

$440

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 2/18

6:19 am-9:11 pm

2 stops13h 52m

Cancun

Wed 2/25

8:00 am-4:27 pm

1 stop9h 27m

$440

Des MoinesMonterrey

DSM - MTY

DSMMTY

Des Moines

Thu 2/5

4:30 pm-2:55 pm

1 stop22h 25m

Monterrey Gen Mariano Escobedo

Thu 2/12

11:00 am-6:47 pm

1 stop7h 47m

$441

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Sun 1/25

5:35 am-1:50 pm

1 stop8h 15m

Cozumel

Fri 1/30

3:05 pm-10:29 pm

1 stop7h 24m

$447

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 3/2

5:24 am-4:45 pm

1 stop10h 21m

Cancun

Thu 3/5

11:00 am-4:27 pm

1 stop6h 27m

$465

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/24

Showing 1-10 of 60 results

...

Best time to book a flight from Des Moines to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico

What is the cheapest month to book a flight from Des Moines to Mexico?

Currently, October is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $241). Flying from Des Moines to Mexico in June is currently the most expensive (average of $479). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MX?

A simple way to save on the total cost of your ticket is to fly from Des Moines to Mexico in the evening. If you’re flexible enough to do this you can expect to save up to 7% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Mexico

See what other customers who have flown with Southwest, Delta, and United Airlines from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,258 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,012 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,115 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Aeromexico

7.4

Good

1,626 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,061 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airport do you fly from for flights from Des Moines to Mexico?
Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.
How long is the flight from Des Moines to Mexico?
Frontier, Delta, and American Airlines can get you from Des Moines to Mexico in just under 6h 36m. Your travel time can differ by up to 10h 34m. Airlines will cover a distance of 1470 mi. This flight may include one or multiple stops.
What are the most popular routes from Des Moines to Mexico?
Most travelers choose Des Moines - Cancun, Des Moines - Cozumel or Des Moines - Puerto Vallarta Ordaz when deciding on the best route from Des Moines to Mexico.
Can I find deals for flights from Des Moines to Mexico that include hotel bookings?
Yes. In addition to deals on Des Moines to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Mexico?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico.
Can I find deals for business class flights from Des Moines to Mexico?
Yes. Cheapflights offers flight deals from Des Moines to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Mexico?
Currently, October is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $241). Flying from Des Moines to Mexico in June is currently the most expensive (average of $479). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Des Moines to Mexico

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$250	Average$627	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$366	Average$676	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$379	Average$638	FlexibilityNo cancel fee	On-time69%
Aeromexico	Cheapest$410	Average$495	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$547	Average$658	FlexibilityNo cancel fee	On-time63%

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$154+ Cheap flights from Des Moines (DSM) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Mexico with Cheapflights

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Cheap flight deals from Des Moines to Mexico

Cheapest flights from Des Moines to MexicoExplore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 25, 2025.

Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 25, 2025.

Find flight deals from Des Moines to Mexico

Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated December 25, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.

Best time to book a flight from Des Moines to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico

What is the cheapest month to book a flight from Des Moines to Mexico?

What is the cheapest time of day to fly from DSM to MX?

Find hourly flight availability from Des Moines to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 25, 2025.

Reviews of airlines servicing Mexico

See what other customers who have flown with Southwest, Delta, and United Airlines from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to Mexico?

How long is the flight from Des Moines to Mexico?

What are the most popular routes from Des Moines to Mexico?

Can I find deals for flights from Des Moines to Mexico that include hotel bookings?

How can I find direct flights from Des Moines to Mexico?

Can I find deals for business class flights from Des Moines to Mexico?

What is the cheapest month to book a flight from Des Moines to Mexico?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Mexico

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Cheapest flights from Des Moines to Mexico
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 25, 2025.