Mexico

$181+ Cheap flights from Des Moines (DSM) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Jun 4 — Jun 111
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Cheap flight deals from Des Moines to Mexico

Cheapest flights from Des Moines to Mexico
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:02 pm
DSM
-
CUN
1 stop16h 18m
Multiple Airlines
Thu 6/1110:25 am
CUN
-
DSM
1 stop11h 02m
Multiple Airlines
Deal found 5/4$316
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:41 pm
DSM
-
CUN
1 stop16h 39m
Multiple Airlines
Thu 6/410:30 am
CUN
-
DSM
1 stop10h 57m
Multiple Airlines
Deal found 4/30$387
This Priceline deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:19 pm
DSM
-
CUN
1 stop22h 30m
Frontier
Sun 7/123:35 pm
CUN
-
DSM
1 stop21h 59m
Frontier
Deal found 5/3$393
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:02 pm
DSM
-
CUN
1 stop16h 18m
Multiple Airlines
Tue 6/1611:11 am
CUN
-
DSM
2 stops26h 20m
Multiple Airlines
Deal found 5/2$408
This Expedia deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/272:19 pm
DSM
-
CUN
1 stop22h 30m
Frontier
Sun 8/23:35 pm
CUN
-
DSM
1 stop21h 59m
Frontier
Deal found 5/4$413
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/183:57 pm
DSM
-
CUN
2 stops21h 54m
Multiple Airlines
Thu 6/2510:25 am
CUN
-
DSM
1 stop11h 22m
Multiple Airlines
Deal found 5/3$429
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/172:16 pm
DSM
-
MEX
1 stop28h 14m
Multiple Airlines
Wed 6/249:45 pm
MEX
-
DSM
2 stops23h 02m
Multiple Airlines
Deal found 5/3$430
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:56 pm
DSM
-
GDL
1 stop22h 56m
Multiple Airlines
Mon 6/227:35 pm
GDL
-
DSM
2 stops40h 56m
Multiple Airlines
Deal found 5/1$478
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:16 pm
DSM
-
MEX
1 stop28h 14m
Multiple Airlines
Mon 6/810:45 pm
MEX
-
DSM
2 stops37h 46m
Multiple Airlines
Deal found 5/2$485
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:56 pm
DSM
-
MEX
1 stop24h 49m
Multiple Airlines
Mon 6/2210:45 pm
MEX
-
DSM
2 stops37h 46m
Multiple Airlines
Deal found 5/1$489
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:16 pm
DSM
-
MEX
1 stop28h 14m
Multiple Airlines
Tue 5/268:40 am
MEX
-
DSM
1 stop27h 51m
Multiple Airlines
Deal found 5/3$493
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/172:16 pm
DSM
-
GDL
1 stop27h 09m
Multiple Airlines
Wed 6/249:30 am
GDL
-
DSM
2 stops29h 28m
Multiple Airlines
Deal found 5/3$503

Find flight deals from Des Moines to Mexico

Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated May 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$316
(Kiwi.com)

One-way from

$181
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$644
Provider with most accurate pricing for Des Moines-Mexico City Benito Juarez flight deals.
Provider most trusted by Cheapflights users for Des Moines-Mexico City Benito Juarez flights.
From Des Moines to Mexico
One-way flight from Des Moines to Mexico
Highest demand for flights based on searches. 17% potential increase in price ($136 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($27 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Fri 8/14

6:55 am-7:31 pm

2 stops12h 36m

Cancun

Wed 8/19

8:05 am-8:58 pm

2 stops12h 53m

$538

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Wed 6/17

2:16 pm-4:25 pm

1 stop27h 09m

Guadalajara Miguel Hidal

Wed 6/24

11:51 am-7:46 pm

1 stop30h 55m

$556

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 6/19

2:16 pm-4:25 pm

1 stop27h 09m

Guadalajara Miguel Hidal

Fri 6/26

10:25 am-9:06 pm

1 stop9h 41m

$569

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 7/1

6:50 am-8:25 pm

2 stops13h 35m

Cancun

Wed 7/8

8:00 am-8:49 pm

2 stops12h 49m

$572

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 6/17

10:24 am-8:25 pm

2 stops10h 01m

Cancun

Wed 6/24

8:00 am-9:08 pm

2 stops13h 08m

$573

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Mon 8/31

5:45 am-11:22 am

1 stop7h 37m

San José del Cabo Los Cabos

Fri 9/4

12:27 pm-10:26 pm

1 stop7h 59m

$581

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Mon 8/31

5:45 am-11:22 am

1 stop7h 37m

San José del Cabo Los Cabos

Fri 9/4

12:27 pm-10:26 pm

1 stop7h 59m

$581

Des MoinesPuerto Vallarta

DSM - PVR

DSMPVR

Des Moines

Mon 8/24

5:45 am-12:11 pm

1 stop7h 26m

Puerto Vallarta Ordaz

Thu 8/27

1:21 pm-10:26 pm

1 stop8h 05m

$590
Quickest round-trip

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 6/15

6:00 am-1:10 pm

1 stop7h 10m

Cancun

Sat 6/20

12:11 pm-7:25 pm

1 stop7h 14m

$593

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Thu 6/18

5:10 am-3:05 pm

2 stops9h 55m

Cancun

Thu 6/25

12:40 pm-11:30 pm

2 stops10h 50m

$598

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/4

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Des Moines to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico

How far ahead should I book a flight from Des Moines to Mexico?

Booking 19 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Mexico. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Des Moines to Mexico?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $192). Flying from Des Moines to Mexico in August is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated May 5, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

8.0

Food

7.0

Entertainment

7.5

Crew

8.6

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Comfort

8.0

Food

7.0

Entertainment

7.5

Crew

8.6

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Comfort

8.0

Food

7.0

Entertainment

7.5

Crew

8.6

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Comfort

8.0

Food

7.0

Entertainment

7.5

Crew

8.6

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Comfort

8.0

Food

7.0

Entertainment

7.5

Crew

8.6

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Comfort

8.0

Food

7.0

Entertainment

7.5

Crew

8.6

Overall

7.9

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Des Moines to Mexico?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Mexico?

    Delta, Aeromexico, and American Airlines can get you from Des Moines to Mexico in just under 7h 37m. Your travel time can differ by up to 4h 59m. Airlines will cover a distance of 1572 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Des Moines to Mexico?

  • Can I find deals for flights from Des Moines to Mexico that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico.

  • Can I find deals for business class flights from Des Moines to Mexico?

    Yes. Cheapflights offers flight deals from Des Moines to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mexico?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $192). Flying from Des Moines to Mexico in August is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Mexico

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Des Moines to Mexico

Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$276Average$481FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$379Average$664FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$382Average$665FlexibilityNo cancel feeOn-time71%
DeltaCheapest$397Average$628FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$569Average$697FlexibilityNo cancel feeOn-time63%

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