Mexico

$158+ Cheap flights from Des Moines (DSM) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/3. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Jun 19 — Jun 261
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Cheap flight deals from Des Moines to Mexico

Cheapest flights from Des Moines to Mexico
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 20, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:16 pm
DSM
-
GDL
1 stop27h 09m
Multiple Airlines
Fri 7/1010:25 am
GDL
-
DSM
1 stop9h 58m
Multiple Airlines
Deal found 5/20$429
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:56 pm
DSM
-
GDL
1 stop22h 58m
Multiple Airlines
Fri 7/310:25 am
GDL
-
DSM
1 stop9h 46m
Multiple Airlines
Deal found 5/19$435
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:56 pm
DSM
-
GDL
1 stop22h 58m
Multiple Airlines
Tue 6/308:30 am
GDL
-
DSM
2 stops28h 01m
Multiple Airlines
Deal found 5/19$437
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:16 pm
DSM
-
CUN
1 stop22h 32m
Multiple Airlines
Wed 7/83:35 pm
CUN
-
DSM
2 stops24h 32m
Multiple Airlines
Deal found 5/17$440
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/102:16 pm
DSM
-
MEX
1 stop28h 14m
Multiple Airlines
Sun 6/288:40 am
MEX
-
DSM
1 stop27h 51m
Multiple Airlines
Deal found 5/20$444
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
-
CUN
2 stops36h 02m
Multiple Airlines
Tue 7/213:35 pm
CUN
-
DSM
1 stop21h 59m
Multiple Airlines
Deal found 5/20$445
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:16 pm
DSM
-
MEX
1 stop28h 14m
Multiple Airlines
Fri 7/1011:00 am
MEX
-
DSM
1 stop9h 23m
Multiple Airlines
Deal found 5/19$451
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/52:19 pm
DSM
-
CUN
1 stop22h 30m
Multiple Airlines
Thu 8/1310:25 am
CUN
-
DSM
1 stop11h 06m
Multiple Airlines
Deal found 5/19$453
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:01 pm
DSM
-
MEX
1 stop23h 04m
Multiple Airlines
Wed 8/198:40 am
MEX
-
DSM
2 stops27h 25m
Multiple Airlines
Deal found 5/16$456
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/31:37 pm
DSM
-
CUN
1 stop24h 47m
Multiple Airlines
Thu 8/1310:25 am
CUN
-
DSM
1 stop11h 06m
Multiple Airlines
Deal found 5/19$456
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:16 pm
DSM
-
MEX
1 stop28h 14m
Multiple Airlines
Wed 7/810:45 pm
MEX
-
DSM
2 stops37h 49m
Multiple Airlines
Deal found 5/18$461
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:56 pm
DSM
-
GDL
1 stop22h 58m
Multiple Airlines
Thu 7/28:30 am
GDL
-
DSM
2 stops28h 01m
Multiple Airlines
Deal found 5/19$466

Find flight deals from Des Moines to Mexico

Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated May 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$429
(Kiwi.com)

One-way from

$158
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$644
Provider with most accurate pricing for Des Moines-Mexico City Benito Juarez flight deals.
Provider most trusted by Cheapflights users for Des Moines-Mexico City Benito Juarez flights.
From Des Moines to Mexico
One-way flight from Des Moines to Mexico
Highest demand for flights based on searches. 18% potential increase in price ($147 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMonterrey

DSM - MTY

DSMMTY

Des Moines

Fri 7/3

10:01 pm-7:20 pm

1 stop22h 19m

Monterrey Gen Mariano Escobedo

Fri 7/10

12:05 pm-9:23 pm

1 stop8h 18m

$476

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 6/28

8:36 pm-4:49 pm

1 stop21h 13m

Guadalajara Miguel Hidal

Tue 7/7

6:10 am-1:34 pm

2 stops30h 24m

$505

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 10/14

5:35 am-12:40 pm

1 stop7h 05m

Cancun

Thu 10/15

1:05 pm-11:30 pm

1 stop10h 25m

$568
Quickest round-trip

Des MoinesMonterrey

DSM - MTY

DSMMTY

Des Moines

Thu 7/2

4:48 pm-8:50 pm

1 stop5h 02m

Monterrey Gen Mariano Escobedo

Thu 7/9

4:42 pm-11:58 pm

1 stop6h 16m

$574

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 7/1

10:24 am-8:25 pm

2 stops10h 01m

Cancun

Wed 7/8

8:00 am-8:49 pm

2 stops12h 49m

$583

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 7/14

2:25 pm-8:15 pm

1 stop5h 50m

Cancun

Sat 7/18

2:10 pm-9:08 pm

1 stop6h 58m

$598

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Fri 7/24

5:10 am-2:00 pm

2 stops8h 50m

Cancun

Tue 7/28

12:40 pm-10:45 pm

2 stops10h 05m

$598

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Fri 9/25

10:15 am-8:15 pm

2 stops10h 00m

Cancun

Tue 9/29

6:03 am-5:42 pm

2 stops11h 39m

$598

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Fri 7/3

5:10 am-3:05 pm

2 stops9h 55m

Cancun

Fri 7/10

12:40 pm-11:30 pm

2 stops10h 50m

$598

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Fri 7/3

7:33 am-8:25 pm

2 stops12h 52m

Cancun

Fri 7/10

8:00 am-5:52 pm

1 stop9h 52m

$598

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/16

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Des Moines to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico

What is the cheapest month to book a flight from Des Moines to Mexico?

Currently, April is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $210). Flying from Des Moines to Mexico in May is currently the most expensive (average of $450). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far ahead should I book a flight from Des Moines to Mexico?

Booking 18 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Mexico. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated May 20, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.9

Food

7.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

7.9

Food

7.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

7.9

Food

7.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

7.9

Food

7.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

7.9

Food

7.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Overall

7.9

Food

7.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Des Moines to Mexico?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Mexico?

    American Airlines, Delta, and Southwest can get you from Des Moines to Mexico in just under 5h 02m. Your travel time can differ by up to 4h 58m. Airlines will cover a distance of 1149 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Des Moines to Mexico?

  • Can I find deals for flights from Des Moines to Mexico that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico.

  • Can I find deals for business class flights from Des Moines to Mexico?

    Yes. Cheapflights offers flight deals from Des Moines to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mexico?

    Currently, April is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $210). Flying from Des Moines to Mexico in May is currently the most expensive (average of $450). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Mexico

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Des Moines to Mexico

Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$276Average$494FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$366Average$668FlexibilityNo cancel feeOn-time71%
DeltaCheapest$397Average$634FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$423Average$666FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$569Average$788FlexibilityNo cancel feeOn-time63%

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