HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mexico

$211+ Cheap flights from Des Moines (DSM) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Mexico with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Mexico

Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$384
(Kiwi.com)

One-way from

$211
(Mytrip)

Popular in

December

Cheapest in

February

Average price

$794
Provider with most accurate pricing for Des Moines-Mexico City Benito Juarez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Mexico City Benito Juarez flights.
Search Deals
From Des Moines to Mexico
Search Deals
One-way flight from Des Moines to Mexico
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2025
Search Deals

Find flight deals from Des Moines to Mexico

Cheapest flights from Des Moines to Mexico
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/97:19 pmDSM - CUN
1 stop12h 57mMultiple Airlines
Sat 6/149:35 amCUN - DSM
1 stop26h 14mMultiple Airlines
Deal found 4/30$384
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/96:00 amDSM - MTY
2 stops27h 35mMultiple Airlines
Sun 5/116:00 amMTY - DSM
1 stop11h 54mMultiple Airlines
Deal found 4/29$451
This Aeromexico deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/122:15 pmDSM - CUN
1 stop6h 05mAeromexico
Tue 5/208:00 amCUN - DSM
1 stop9h 50mAeromexico
Deal found 4/28$453
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/126:30 amDSM - CUN
2 stops13h 50mDelta
Tue 5/208:00 amCUN - DSM
2 stops13h 06mDelta
Deal found 4/28$457
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/92:44 pmDSM - MTY
1 stop6h 16mAmerican Airlines
Sun 5/1110:00 amMTY - DSM
1 stop5h 37mAmerican Airlines
Deal found 4/29$465
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/212:39 pmDSM - SJD
1 stop23h 48mMultiple Airlines
Fri 7/251:37 pmSJD - DSM
1 stop6h 58mMultiple Airlines
Deal found 4/29$469
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/85:27 pmDSM - GDL
1 stop6h 28mAmerican Airlines
Tue 5/206:00 amGDL - DSM
1 stop15h 56mAmerican Airlines
Deal found 4/30$470
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/127:21 pmDSM - CUN
1 stop18h 29mAmerican Airlines
Thu 6/1912:05 pmCUN - DSM
1 stop12h 01mAmerican Airlines
Deal found 4/29$476
This lol.travel deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/135:40 amDSM - PVR
1 stop7h 36mAeromexico
Fri 6/201:26 pmPVR - DSM
1 stop8h 37mAeromexico
Deal found 4/29$479
This Aeromexico deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/85:35 amDSM - MEX
2 stops9h 45mAeromexico
Mon 5/127:00 amMEX - DSM
2 stops14h 30mAeromexico
Deal found 4/30$488
This lastminute.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/135:40 amDSM - SJD
1 stop7h 50mAeromexico
Fri 6/2012:35 pmSJD - DSM
1 stop8h 28mAeromexico
Deal found 4/29$492
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/123:48 pmDSM - MEX
1 stop30h 22mMultiple Airlines
Thu 6/1911:45 amMEX - DSM
1 stop23h 49mMultiple Airlines
Deal found 4/30$492

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.

Fly from

Des Moines

Fly to

Mexico

Route

Depart

Return

Price

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 6/9

7:19 pm-8:16 am

1 stop12h 57m

Cancun

Sat 6/14

9:35 am-11:49 am

1 stop26h 14m

$384

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 5/12

2:15 pm-8:20 pm

1 stop6h 05m

Cancun

Tue 5/20

8:00 am-5:50 pm

1 stop9h 50m

$453

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 5/12

6:30 am-8:20 pm

2 stops13h 50m

Cancun

Tue 5/20

8:00 am-9:06 pm

2 stops13h 06m

$457

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Mon 7/21

2:39 pm-12:27 pm

1 stop23h 48m

San José del Cabo Los Cabos

Fri 7/25

1:37 pm-10:35 pm

1 stop6h 58m

$469

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Thu 6/12

7:21 pm-1:50 pm

1 stop18h 29m

Cancun

Thu 6/19

12:05 pm-12:06 am

1 stop12h 01m

$476

Des MoinesPuerto Vallarta

DSM - PVR

DSMPVR

Des Moines

Fri 6/13

5:40 am-12:16 pm

1 stop7h 36m

Puerto Vallarta Ordaz

Fri 6/20

1:26 pm-11:03 pm

1 stop8h 37m

$479

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 5/8

5:35 am-2:20 pm

2 stops9h 45m

Mexico City Benito Juarez

Mon 5/12

7:00 am-10:30 pm

2 stops14h 30m

$488

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 6/12

3:48 pm-9:10 pm

1 stop30h 22m

Mexico City Benito Juarez

Thu 6/19

11:45 am-12:34 pm

1 stop23h 49m

$492

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Fri 6/13

5:40 am-11:30 am

1 stop7h 50m

San José del Cabo Los Cabos

Fri 6/20

12:35 pm-11:03 pm

1 stop8h 28m

$492

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Wed 7/16

5:00 am-3:20 pm

1 stop11h 20m

Cozumel

Wed 7/30

4:20 pm-11:49 pm

1 stop6h 29m

$493

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 47 results
1
2
3
...
5

Best time to book a flight from Des Moines to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico

What is the cheapest month to book a flight from Des Moines to Mexico?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $400). Flying from Des Moines to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MX?

Find hourly flight availability from Des Moines to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Mexico as you normally would.

Rainfall in Mexico by month

Plan your trip to Mexico by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mexico ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico when rainfall is around 0.0 in.

Temperature in Mexico by month

Plan your trip to Mexico by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mexico, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated May 1, 2025.
Peruse reviews from past customers who have flown with Delta, KLM and LATAM Airlines from Des Moines to Mexico to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
KLM
7.8
Good
1,334 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,767 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Aeromexico
7.5
Good
1,698 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Mexico?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to Mexico one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $229. Users have also found prices from $266 and $268 on Delta and Aeromexico, respectively.

  • What are the most popular routes from Des Moines to Mexico?

    Most travelers choose Des Moines - Cancun, Des Moines - Cozumel or Des Moines - Mexico City Benito Juarez when deciding on the best route from Des Moines to Mexico.

  • Can I find deals for flights from Des Moines to Mexico that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico.

  • Can I find deals for business class flights from Des Moines to Mexico?

    Yes. Cheapflights offers flight deals from Des Moines to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mexico?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $400). Flying from Des Moines to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Seattle flights
Des Moines to Denver flights
Omaha to Dallas/Fort Worth flights
Cedar Rapids to Denver flights
Cedar Rapids to Dallas/Fort Worth flights
Omaha to O'Hare Intl flights
Omaha to Sky Harbor Intl flights
Des Moines to Seattle flights
Omaha to LaGuardia flights
Des Moines to LaGuardia flights
Omaha to Orlando flights
Omaha to Denver flights
Des Moines to Sky Harbor Intl flights
Cedar Rapids to Seattle flights
Des Moines to Orlando flights
Omaha to Las Vegas flights
Des Moines to Reagan-National flights
Des Moines to Dallas/Fort Worth flights
Cedar Rapids to Orlando flights
Des Moines to John F Kennedy Intl flights
Omaha to John F Kennedy Intl flights
Des Moines to O'Hare Intl flights
Des Moines to Dulles Intl flights
Omaha to Atlanta flights
Cedar Rapids to Sky Harbor Intl flights
Omaha to Newark flights
Moline to Dallas/Fort Worth flights
Omaha to Hobby flights
Omaha to Miami flights
Des Moines to Las Vegas flights
Moline to Denver flights
Omaha to San Francisco flights
Omaha to Love Field flights
Moline to Orlando flights
Omaha to Nashville flights
Cedar Rapids to Reagan-National flights
Omaha to Cancún flights
Omaha to Dulles Intl flights
Cedar Rapids to Cancún flights
Omaha to Los Angeles flights
Des Moines to Cancún flights
Omaha to Boston flights
Des Moines to Baltimore flights
Des Moines to Hobby flights
Cedar Rapids to Dulles Intl flights
Omaha to Minneapolis flights
Cedar Rapids to Atlanta flights
Omaha to Midway flights
Des Moines to Salt Lake City flights
Des Moines to George Bush Intcntl flights

Top 5 airlines flying from Des Moines to Mexico

Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$349Average$582FlexibilityNo cancel feeOn-timeN/A
AeromexicoCheapest$350Average$493FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$421Average$691FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$441Average$629FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$460Average$646FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.