$139+ Cheap flights from Des Moines (DSM) to Mexico
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Nov 6 — Nov 131
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Des Moines to MexicoExplore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 7, 2026.
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am -
1 stop29h 37m
Thu 11/122:07 pm -
1 stop24h 29m
Deal found 10/6![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:15 am -
1 stop29h 42m
Thu 11/122:07 pm -
1 stop24h 29m
Deal found 10/6![Multiple Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:20 am -
1 stop29h 37m
Thu 12/32:07 pm -
1 stop19h 43m
Deal found 10/4![Multiple Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am -
1 stop29h 37m
Mon 11/169:02 am -
1 stop10h 33m
Deal found 10/6![Multiple Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am -
1 stop29h 37m
Wed 11/117:00 am -
2 stops32h 25m
Deal found 10/6![Multiple Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:15 am -
1 stop29h 42m
Tue 11/103:35 pm -
2 stops22h 20m
Deal found 10/6![Multiple Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:15 am -
1 stop29h 42m
Wed 11/117:00 am -
2 stops32h 25m
Deal found 10/6![Multiple Airlines logo]()
$372
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:15 am -
1 stop29h 42m
Sun 11/88:00 am -
2 stops35h 35m
Deal found 10/6![Multiple Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am -
1 stop29h 37m
Fri 11/139:02 am -
1 stop10h 33m
Deal found 10/6![Multiple Airlines logo]()
$386
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:15 am -
1 stop29h 42m
Thu 11/52:07 pm -
1 stop24h 29m
Deal found 10/6![Multiple Airlines logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:30 am -
1 stop29h 27m
Thu 11/122:07 pm -
1 stop24h 29m
Deal found 10/6![Multiple Airlines logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am -
2 stops36h 50m
Mon 11/168:00 am -
1 stop11h 35m
Deal found 10/6![Multiple Airlines logo]()
$422
Best flights from Des Moines to MexicoDiscover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 7, 2026.
Discover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 7, 2026.
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/38:00 am -
1 stop6h 37m
Mon 3/83:15 pm -
1 stop9h 24m
Deal found 10/6![United Airlines logo]()
$523
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:31 pm -
1 stop7h 03m
Tue 11/246:52 am -
1 stop11h 35m
Deal found 10/3![American Airlines logo]()
$566
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/315:45 am -
2 stops12h 02m
Wed 2/103:10 pm -
1 stop8h 19m
Deal found 10/2![Delta logo]()
$570
This Southwest deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/215:10 am -
2 stops10h 45m
Fri 2/2612:05 pm -
2 stops11h 45m
Deal found 10/4![Southwest logo]()
$585
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:30 pm -
1 stop20h 20m
Mon 11/2310:55 pm -
2 stops37h 41m
Deal found 10/2![Multiple Airlines logo]()
$600
This Aeromexico deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
2 stops15h 35m
Tue 11/108:35 am -
2 stops14h 00m
Deal found 10/6![Aeromexico logo]()
$637
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:30 am -
1 stop9h 15m
Fri 11/138:39 am -
2 stops16h 03m
Deal found 10/6![United Airlines logo]()
$561
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:27 pm -
1 stop22h 07m
Tue 11/245:30 pm -
1 stop15h 37m
Deal found 10/3![American Airlines logo]()
$572
This Delta deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:15 am -
2 stops12h 40m
Thu 11/58:00 am -
2 stops12h 14m
Deal found 10/3![Delta logo]()
$600
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/185:20 am -
2 stops13h 25m
Tue 2/2312:10 pm -
2 stops10h 25m
Deal found 10/5![Southwest logo]()
$600
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:30 am -
1 stop8h 48m
Tue 11/102:11 pm -
1 stop7h 19m
Deal found 10/4![United Airlines logo]()
$617
This Delta deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2310:15 am -
2 stops10h 00m
Wed 1/278:15 am -
2 stops14h 09m
Deal found 10/3![Delta logo]()
$625
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/286:55 am -
1 stop8h 25m
Mon 2/19:40 am -
2 stops12h 00m
Deal found 10/6![Southwest logo]()
$625
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:27 pm -
1 stop15h 30m
Tue 11/242:55 pm -
1 stop8h 49m
Deal found 10/3![American Airlines logo]()
$637
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/217:00 pm -
2 stops17h 43m
Wed 2/2412:49 pm -
2 stops9h 39m
Deal found 10/5![United Airlines logo]()
$621
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/227:00 am -
2 stops8h 30m
Wed 1/278:15 am -
2 stops14h 09m
Deal found 10/5![Delta logo]()
$625
This Aeromexico deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:30 am -
2 stops27h 25m
Tue 12/89:51 am -
2 stops12h 47m
Deal found 10/2![Aeromexico logo]()
$760
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:27 pm -
1 stop16h 57m
Wed 11/114:25 pm -
1 stop16h 21m
Deal found 10/2![American Airlines logo]()
$641
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:45 am -
2 stops12h 15m
Wed 12/27:25 pm -
2 stops14h 56m
Deal found 10/6![Delta logo]()
$641
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:09 pm -
2 stops17h 34m
Wed 11/251:57 pm -
1 stop7h 58m
Deal found 10/4![United Airlines logo]()
$645
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/255:45 am -
1 stop9h 30m
Thu 3/46:40 am -
2 stops10h 10m
Deal found 10/4![Delta logo]()
$641
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/71:23 pm -
2 stops9h 12m
Wed 1/275:45 am -
2 stops10h 26m
Deal found 10/6![United Airlines logo]()
$649
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/47:57 pm -
1 stop18h 04m
Sun 2/71:38 pm -
1 stop9h 10m
Deal found 10/6![American Airlines logo]()
$720
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:20 am -
2 stops9h 10m
Wed 1/208:15 am -
2 stops9h 35m
Deal found 10/7![Delta logo]()
$645
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:00 am -
2 stops13h 07m
Wed 11/113:50 pm -
1 stop6h 40m
Deal found 10/6![United Airlines logo]()
$659
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:31 pm -
1 stop20h 43m
Tue 11/241:13 pm -
1 stop10h 10m
Deal found 10/3![American Airlines logo]()
$739
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:20 am -
2 stops9h 10m
Mon 1/253:20 pm -
1 stop7h 04m
Deal found 10/7![Delta logo]()
$645
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:30 am -
2 stops9h 25m
Sun 12/69:05 am -
1 stop7h 08m
Deal found 10/4![United Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:23 am -
1 stop17h 15m
Wed 1/206:52 am -
1 stop9h 19m
Deal found 10/5![American Airlines logo]()
$790
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/255:45 am -
1 stop9h 30m
Sun 2/288:20 am -
2 stops13h 04m
Deal found 10/4![Delta logo]()
$661
Last-minute flights from Des Moines to MexicoDiscover last-minute flight deals from Des Moines to Mexico. Data last updated October 7, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Mexico. Data last updated October 7, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:15 am -
1 stop29h 42m
Thu 11/52:07 pm -
1 stop24h 29m
Deal found 10/6![Multiple Airlines logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:15 am -
1 stop29h 42m
Thu 11/122:07 pm -
1 stop24h 29m
Deal found 10/6![Multiple Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:15 am -
1 stop29h 42m
Tue 11/103:35 pm -
2 stops22h 20m
Deal found 10/6![Multiple Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:15 am -
1 stop29h 42m
Wed 11/117:00 am -
2 stops32h 25m
Deal found 10/6![Multiple Airlines logo]()
$372
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:15 am -
1 stop29h 42m
Sun 11/88:00 am -
2 stops35h 35m
Deal found 10/6![Multiple Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:30 am -
1 stop29h 27m
Thu 11/122:07 pm -
1 stop24h 29m
Deal found 10/6![Multiple Airlines logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am -
1 stop29h 37m
Thu 11/122:07 pm -
1 stop24h 29m
Deal found 10/6![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am -
1 stop29h 37m
Mon 11/169:02 am -
1 stop10h 33m
Deal found 10/6![Multiple Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am -
1 stop29h 37m
Wed 11/117:00 am -
2 stops32h 25m
Deal found 10/6![Multiple Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am -
1 stop29h 37m
Fri 11/139:02 am -
1 stop10h 33m
Deal found 10/6![Multiple Airlines logo]()
$386
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:20 am -
2 stops36h 50m
Mon 11/168:00 am -
1 stop11h 35m
Deal found 10/6![Multiple Airlines logo]()
$422
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:20 am -
1 stop29h 37m
Thu 12/32:07 pm -
1 stop19h 43m
Deal found 10/4![Multiple Airlines logo]()
$338
One-way flights from Des Moines to MexicoSearch for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated October 7, 2026.
Search for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated October 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:15 am -
1 stop29h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1010:00 am -
2 stops47h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/159:59 pm -
2 stops41h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Multiple Airlines logo]()
$190
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:00 am -
1 stop7h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![American Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/159:59 pm -
2 stops37h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Multiple Airlines logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/159:59 pm -
2 stops36h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:00 pm -
2 stops34h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$212
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:45 pm -
2 stops17h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![United Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:11 pm -
2 stops34h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:15 am -
3 stops58h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$217
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:12 pm -
1 stop18h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![American Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:20 am -
2 stops38h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Multiple Airlines logo]()
$219
Find flight deals from Des Moines to Mexico
Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated October 7, 2026.
Round-trip from | $314 (Kiwi.com) |
|---|---|
One-way from | $139 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 7, 2026.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesMexico City
DSM Des Moines - MEX Mexico City Benito Juarez
DSMMEX
Des Moines
Sun 1/10
10:00 am-9:40 am
2 stops47h 40m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$172
Des MoinesSan José del Cabo
DSM Des Moines - SJD San José del Cabo Los Cabos
DSMSJD
Des Moines
Fri 1/15
9:59 pm-10:35 am
2 stops37h 36m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$206
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Mon 11/2
6:45 pm-11:25 am
2 stops15h 40m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$214
Quickest round-trip
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Wed 2/24
8:00 am-3:37 pm
1 stop6h 37m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$214
Des MoinesMexico City
DSM Des Moines - MEX Mexico City Benito Juarez
DSMMEX
Des Moines
Wed 11/25
7:20 am-9:45 pm
2 stops38h 25m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$219
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Sun 12/6
3:15 pm-10:45 pm
1 stop31h 30m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$245
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Sun 1/31
10:00 am-10:00 am
2 stops23h 00m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$245
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Mon 12/7
9:18 pm-7:35 am
2 stops34h 17m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$247
Des MoinesMexico City
DSM Des Moines - MEX Mexico City Benito Juarez
DSMMEX
Des Moines
Fri 10/30
10:00 pm-7:05 am
2 stops34h 05m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$251
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Wed 10/28
8:00 am-2:37 pm
1 stop6h 37m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$252
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
DSM-GDL
DSM-MEX
DSM-PVR
DSM-CUN
DSM-SJD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Mexico
DSM-MX0
DSM-GDL
DSM-MEX
DSM-PVR
DSM-CUN
What is the cheapest month to book a flight from Des Moines to Mexico?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $594). Flying from Des Moines to Mexico in December is currently the most expensive (average of $778). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Des Moines to Mexico?
Booking 16 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Mexico. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Mexico
Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated October 7, 2026.
See what other customers who have flown with Southwest,Delta, andAeromexico from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
7.9
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Mexico
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Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Des Moines to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Mexico flights
Browse other Des Moines and Mexico flight options. Last updated on October 7, 2026.
Popular flight searches
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Des Moines to Mexico flights
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Consider these flights traveling to Mexico regions.
Top 5 airlines flying from Des Moines to Mexico
Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$229 | Average$620 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$459 | Average$695 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$459 | Average$700 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$467 | Average$757 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$569 | Average$700 | FlexibilityNo cancel fee | On-time63% |