$179+ Cheap flights from Des Moines (DSM) to Mexico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Aug 26 — Sep 21
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to MexicoExplore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm
DSM
- GDL
1 stop19h 59m
Multiple Airlines
Sat 9/58:02 am
GDL
- DSM
2 stops34h 55m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:38 pm
DSM
- GDL
1 stop21h 11m
Multiple Airlines
Sat 9/58:02 am
GDL
- DSM
2 stops34h 55m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:44 pm
DSM
- GDL
1 stop21h 36m
Multiple Airlines
Thu 8/2710:25 am
GDL
- DSM
1 stop9h 35m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$415
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:44 pm
DSM
- GDL
1 stop21h 36m
Multiple Airlines
Mon 8/2410:25 am
GDL
- DSM
1 stop8h 23m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$418
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:44 pm
DSM
- GDL
1 stop21h 36m
Multiple Airlines
Fri 8/288:46 am
GDL
- DSM
1 stop9h 02m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$436
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:06 pm
DSM
- GDL
1 stop19h 43m
Multiple Airlines
Thu 8/2710:25 am
GDL
- DSM
1 stop9h 35m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$437
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm
DSM
- GDL
1 stop19h 59m
Multiple Airlines
Fri 8/288:46 am
GDL
- DSM
1 stop9h 02m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$439
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:44 pm
DSM
- GDL
1 stop21h 36m
Multiple Airlines
Wed 8/265:25 pm
GDL
- DSM
2 stops25h 29m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$440
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:06 pm
DSM
- GDL
1 stop26h 52m
Multiple Airlines
Thu 8/2710:25 am
GDL
- DSM
1 stop9h 35m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$444
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:42 pm
DSM
- GDL
1 stop30h 12m
Multiple Airlines
Sun 10/116:00 am
GDL
- DSM
2 stops30h 18m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$445
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:06 pm
DSM
- GDL
1 stop26h 52m
Multiple Airlines
Mon 8/2410:25 am
GDL
- DSM
1 stop8h 23m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$446
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:38 pm
DSM
- MEX
1 stop26h 07m
Multiple Airlines
Thu 8/276:00 am
MEX
- DSM
2 stops14h 00m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$462
Best flights from Des Moines to MexicoDiscover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.
Discover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:39 pm
DSM
- SJD
1 stop20h 38m
American Airlines
Thu 9/1710:51 am
SJD
- DSM
1 stop20h 26m
American Airlines
Deal found 7/27![American Airlines logo]()
$531
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:58 pm
DSM
- GDL
2 stops50h 42m
Multiple Airlines
Thu 9/1710:37 am
GDL
- DSM
1 stop9h 29m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$550
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:55 am
DSM
- CUN
2 stops13h 33m
Delta
Tue 10/203:25 pm
CUN
- DSM
1 stop7h 08m
Delta
Deal found 7/26![Delta logo]()
$562
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/115:55 am
DSM
- SJD
2 stops9h 00m
Southwest
Fri 1/151:35 pm
SJD
- DSM
1 stop6h 45m
Southwest
Deal found 7/24![Southwest logo]()
$571
This Aeromexico deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:40 am
DSM
- BJX
2 stops14h 55m
Aeromexico
Tue 10/136:05 pm
BJX
- DSM
2 stops23h 04m
Aeromexico
Deal found 7/24![Aeromexico logo]()
$598
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:21 pm
DSM
- CZM
2 stops21h 21m
United Airlines
Tue 9/153:52 pm
CZM
- DSM
1 stop6h 38m
United Airlines
Deal found 7/26![United Airlines logo]()
$611
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:41 am
DSM
- SJD
1 stop8h 30m
American Airlines
Fri 10/21:17 pm
SJD
- DSM
2 stops18h 00m
American Airlines
Deal found 7/23![American Airlines logo]()
$546
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:25 pm
DSM
- CUN
2 stops7h 50m
Delta
Thu 10/228:00 am
CUN
- DSM
2 stops12h 51m
Delta
Deal found 7/23![Delta logo]()
$566
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:56 pm
DSM
- MTY
1 stop19h 19m
Multiple Airlines
Thu 9/1712:01 pm
MTY
- DSM
1 stop8h 05m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$568
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:35 am
DSM
- CUN
2 stops8h 05m
Southwest
Mon 10/191:05 pm
CUN
- DSM
1 stop9h 50m
Southwest
Deal found 7/25![Southwest logo]()
$598
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:52 pm
DSM
- SJD
1 stop17h 49m
American Airlines
Tue 10/131:23 pm
SJD
- DSM
2 stops17h 52m
American Airlines
Deal found 7/22![American Airlines logo]()
$546
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:21 pm
DSM
- CZM
2 stops21h 21m
United Airlines
Sat 9/123:52 pm
CZM
- DSM
1 stop6h 38m
United Airlines
Deal found 7/24![United Airlines logo]()
$615
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 am
DSM
- CUN
2 stops8h 22m
Delta
Thu 9/102:00 pm
CUN
- DSM
2 stops19h 38m
Delta
Deal found 7/24![Delta logo]()
$573
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:30 pm
DSM
- MEX
1 stop22h 00m
Multiple Airlines
Mon 10/2611:00 am
MEX
- DSM
1 stop8h 21m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$574
This Aeromexico deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:45 am
DSM
- MTY
1 stop11h 35m
Aeromexico
Fri 1/88:02 am
MTY
- DSM
1 stop8h 25m
Aeromexico
Deal found 7/23![Aeromexico logo]()
$656
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:14 pm
DSM
- BJX
1 stop20h 59m
American Airlines
Thu 9/176:00 am
BJX
- DSM
1 stop26h 17m
American Airlines
Deal found 7/27![American Airlines logo]()
$548
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/196:00 am
DSM
- MEX
2 stops10h 50m
United Airlines
Thu 1/287:50 am
MEX
- DSM
1 stop6h 30m
United Airlines
Deal found 7/23![United Airlines logo]()
$636
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:00 am
DSM
- SJD
2 stops9h 10m
Southwest
Sat 11/1410:05 am
SJD
- DSM
2 stops8h 35m
Southwest
Deal found 7/22![Southwest logo]()
$667
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am
DSM
- CUN
2 stops8h 10m
Delta
Sat 10/318:00 am
CUN
- DSM
2 stops12h 00m
Delta
Deal found 7/23![Delta logo]()
$611
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:11 pm
DSM
- CUN
2 stops20h 51m
United Airlines
Fri 10/231:12 pm
CUN
- DSM
2 stops10h 23m
United Airlines
Deal found 7/25![United Airlines logo]()
$651
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:27 pm
DSM
- PVR
1 stop16h 57m
American Airlines
Sun 11/154:25 pm
PVR
- DSM
1 stop16h 25m
American Airlines
Deal found 7/22![American Airlines logo]()
$592
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:45 am
DSM
- CUN
2 stops13h 04m
Delta
Tue 9/298:00 am
CUN
- DSM
2 stops14h 26m
Delta
Deal found 7/27![Delta logo]()
$618
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am
DSM
- BJX
1 stop8h 43m
United Airlines
Fri 10/911:47 am
BJX
- DSM
2 stops11h 01m
United Airlines
Deal found 7/24![United Airlines logo]()
$654
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:41 am
DSM
- PVR
1 stop6h 37m
American Airlines
Mon 9/143:46 pm
PVR
- DSM
2 stops16h 31m
American Airlines
Deal found 7/27![American Airlines logo]()
$596
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:15 am
DSM
- CUN
2 stops12h 35m
Delta
Wed 10/78:00 am
CUN
- DSM
2 stops12h 49m
Delta
Deal found 7/27![Delta logo]()
$622
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:22 pm
DSM
- PVR
1 stop18h 56m
American Airlines
Sat 10/103:53 pm
PVR
- DSM
1 stop6h 14m
American Airlines
Deal found 7/23![American Airlines logo]()
$596
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:15 pm
DSM
- SJD
1 stop17h 48m
United Airlines
Wed 12/912:49 pm
SJD
- DSM
1 stop8h 41m
United Airlines
Deal found 7/22![United Airlines logo]()
$662
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:40 am
DSM
- PVR
1 stop7h 48m
Delta
Sun 9/131:29 pm
PVR
- DSM
1 stop7h 57m
Delta
Deal found 7/23![Delta logo]()
$638
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
DSM
- BJX
1 stop7h 09m
American Airlines
Tue 10/135:35 am
BJX
- DSM
1 stop8h 36m
American Airlines
Deal found 7/25![American Airlines logo]()
$604
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:55 pm
DSM
- SJD
2 stops19h 53m
United Airlines
Tue 10/131:44 pm
SJD
- DSM
2 stops24h 36m
United Airlines
Deal found 7/22![United Airlines logo]()
$666
Last-minute flights from Des Moines to MexicoDiscover last-minute flight deals from Des Moines to Mexico. Data last updated July 27, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Mexico. Data last updated July 27, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:44 pm
DSM
- GDL
1 stop21h 36m
Multiple Airlines
Thu 8/2710:25 am
GDL
- DSM
1 stop9h 35m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$415
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:44 pm
DSM
- GDL
1 stop21h 36m
Multiple Airlines
Mon 8/2410:25 am
GDL
- DSM
1 stop8h 23m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$418
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:44 pm
DSM
- GDL
1 stop21h 36m
Multiple Airlines
Fri 8/288:46 am
GDL
- DSM
1 stop9h 02m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$436
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:44 pm
DSM
- GDL
1 stop21h 36m
Multiple Airlines
Wed 8/265:25 pm
GDL
- DSM
2 stops25h 29m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$440
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:06 pm
DSM
- GDL
1 stop19h 43m
Multiple Airlines
Thu 8/2710:25 am
GDL
- DSM
1 stop9h 35m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$437
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:06 pm
DSM
- GDL
1 stop26h 52m
Multiple Airlines
Thu 8/2710:25 am
GDL
- DSM
1 stop9h 35m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$444
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:06 pm
DSM
- GDL
1 stop26h 52m
Multiple Airlines
Mon 8/2410:25 am
GDL
- DSM
1 stop8h 23m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$446
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm
DSM
- GDL
1 stop19h 59m
Multiple Airlines
Sat 9/58:02 am
GDL
- DSM
2 stops34h 55m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm
DSM
- GDL
1 stop19h 59m
Multiple Airlines
Fri 8/288:46 am
GDL
- DSM
1 stop9h 02m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$439
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm
DSM
- GDL
1 stop19h 59m
Multiple Airlines
Sun 8/3010:25 am
GDL
- DSM
2 stops26h 09m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$452
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:38 pm
DSM
- GDL
1 stop21h 11m
Multiple Airlines
Sat 9/58:02 am
GDL
- DSM
2 stops34h 55m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:38 pm
DSM
- MEX
1 stop26h 07m
Multiple Airlines
Thu 8/276:00 am
MEX
- DSM
2 stops14h 00m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$462
One-way flights from Des Moines to MexicoSearch for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated July 27, 2026.
Search for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated July 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/309:50 pm
DSM
- GDL
1 stop19h 59m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$179
This Frontier deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:19 pm
DSM
- GDL
1 stop10h 51m
Frontier
Deal found 7/23![Frontier logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:06 pm
DSM
- MEX
1 stop24h 39m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:54 pm
DSM
- GDL
2 stops33h 02m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$196
This FlightHub deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:51 pm
DSM
- MEX
1 stop26h 09m
Frontier
Deal found 7/23![Frontier logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:51 pm
DSM
- MEX
1 stop27h 39m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:44 pm
DSM
- PVR
2 stops42h 11m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:00 am
DSM
- MLM
2 stops11h 35m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/139:44 pm
DSM
- MEX
2 stops34h 41m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:21 pm
DSM
- PVR
2 stops37h 19m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:06 pm
DSM
- MTY
2 stops34h 25m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$243
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:42 pm
DSM
- CUN
1 stop15h 12m
American Airlines
Deal found 7/24![American Airlines logo]()
$249
Find flight deals from Des Moines to Mexico
Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated July 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $403 (Kiwi.com) |
One-way from | $179 (Kiwi.com) |
Popular in | December |
Cheapest in | March |
Average price | $751 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Thu 9/10
5:39 pm-12:17 pm
1 stop20h 38m
San José del Cabo Los Cabos
Thu 9/17
10:51 am-9:17 am
1 stop20h 26m
$531
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Tue 9/29
6:41 am-1:11 pm
1 stop8h 30m
San José del Cabo Los Cabos
Fri 10/2
1:17 pm-9:17 am
2 stops18h 00m
$546
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Sat 10/10
7:52 pm-11:41 am
1 stop17h 49m
San José del Cabo Los Cabos
Tue 10/13
1:23 pm-9:15 am
2 stops17h 52m
$546
Des MoinesLeón
DSM - BJX
DSMBJX
Des Moines
Thu 9/10
4:14 pm-12:13 pm
1 stop20h 59m
León Del Bajio
Thu 9/17
6:00 am-9:17 am
1 stop26h 17m
$548
Des MoinesGuadalajara
DSM - GDL
DSMGDL
Des Moines
Thu 9/10
1:58 pm-3:40 pm
2 stops50h 42m
Guadalajara Miguel Hidal
Thu 9/17
10:37 am-9:06 pm
1 stop9h 29m
$550
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Fri 10/9
6:55 am-8:28 pm
2 stops13h 33m
Cancun
Tue 10/20
3:25 pm-10:33 pm
1 stop7h 08m
$562
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Sat 10/17
12:25 pm-8:15 pm
2 stops7h 50m
Cancun
Thu 10/22
8:00 am-8:51 pm
2 stops12h 51m
$566
Des MoinesMonterrey
DSM - MTY
DSMMTY
Des Moines
Thu 9/10
9:56 pm-4:15 pm
1 stop19h 19m
Monterrey Gen Mariano Escobedo
Thu 9/17
12:01 pm-9:06 pm
1 stop8h 05m
$568
Quickest round-trip
Des MoinesSan José del Cabo
DSM - SJD
DSMSJD
Des Moines
Mon 1/11
5:55 am-1:55 pm
2 stops9h 00m
San José del Cabo Los Cabos
Fri 1/15
1:35 pm-9:20 pm
1 stop6h 45m
$571
Des MoinesCancún
DSM - CUN
DSMCUN
Des Moines
Mon 9/7
6:00 am-2:22 pm
2 stops8h 22m
Cancun
Thu 9/10
2:00 pm-9:38 am
2 stops19h 38m
$573
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
DSM-SJD
DSM-GDL
DSM-CUN
DSM-BJX
DSM-CZM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Mexico
DSM-MX0
DSM-SJD
DSM-GDL
DSM-CUN
DSM-BJX
What is the cheapest month to book a flight from Des Moines to Mexico?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $559). Flying from Des Moines to Mexico in December is currently the most expensive (average of $797). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Des Moines to Mexico?
Booking 17 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Mexico. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Mexico
Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated July 27, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Mexico
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Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Des Moines to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Mexico flights
Browse other Des Moines and Mexico flight options. Last updated on July 27, 2026.
Popular flight searches
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Des Moines to Mexico flights
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Consider these flights traveling to Mexico regions.
Top 5 airlines flying from Des Moines to Mexico
Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$494 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$423 | Average$679 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$441 | Average$706 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$465 | Average$705 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$569 | Average$697 | FlexibilityNo cancel fee | On-time63% |