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$157+ Cheap flights from Des Moines (DSM) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Jan 19 — Jan 261
Mon 1/19
Mon 1/26
1 adult, Economy
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Cheap flight deals from Des Moines to Mexico

Cheapest flights from Des Moines to Mexico
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 20, 2025.

This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:30 amDSM - CUN
1 stop9h 20mUnited Airlines
Fri 12/268:15 amCUN - DSM
1 stop7h 18mUnited Airlines
Deal found 12/17$456
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 amDSM - CUN
1 stop5h 54mUnited Airlines
Thu 12/2512:36 pmCUN - DSM
1 stop8h 54mUnited Airlines
Deal found 12/17$474
This Priceline deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:29 pmDSM - CUN
1 stop19h 43mFrontier
Mon 12/294:58 pmCUN - DSM
1 stop21h 42mFrontier
Deal found 12/17$483
This Expedia deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:29 pmDSM - CUN
1 stop19h 43mFrontier
Mon 12/294:58 pmCUN - DSM
1 stop21h 42mFrontier
Deal found 12/17$513
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:46 pmDSM - CZM
2 stops18h 37mUnited Airlines
Thu 12/252:25 pmCZM - DSM
2 stops20h 25mUnited Airlines
Deal found 12/17$517
This United Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 amDSM - CUN
1 stop6h 34mUnited Airlines
Mon 12/293:18 pmCUN - DSM
1 stop7h 22mUnited Airlines
Deal found 12/18$519
This Aeromexico deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:35 amDSM - CZM
1 stop8h 40mAeromexico
Fri 12/263:30 pmCZM - DSM
1 stop7h 01mAeromexico
Deal found 12/17$523
This United Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:06 pmDSM - CZM
2 stops20h 17mUnited Airlines
Tue 12/232:25 pmCZM - DSM
2 stops31h 15mUnited Airlines
Deal found 12/18$535
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:59 amDSM - CUN
2 stops8h 31mDelta
Fri 12/268:15 amCUN - DSM
2 stops13h 29mDelta
Deal found 12/17$538
This United Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:06 pmDSM - CUN
2 stops17h 19mUnited Airlines
Tue 12/233:18 pmCUN - DSM
1 stop7h 22mUnited Airlines
Deal found 12/18$543
This United Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:30 amDSM - CUN
1 stop7h 48mUnited Airlines
Sun 12/286:30 amCUN - DSM
2 stops9h 03mUnited Airlines
Deal found 12/19$547
This United Airlines deal was found by Cheapflights users on 12/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:30 amDSM - CUN
1 stop7h 48mUnited Airlines
Sat 12/276:30 amCUN - DSM
1 stop8h 49mUnited Airlines
Deal found 12/19$549

Find flight deals from Des Moines to Mexico

Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated December 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$361
(Kiwi.com)

One-way from

$157
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$948
Provider with most accurate pricing for Des Moines-Mexico City Benito Juarez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Mexico City Benito Juarez flights.
Search Deals
From Des Moines to Mexico
Search Deals
One-way flight from Des Moines to Mexico
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($181 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 20, 2025.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.

Fly from

Des Moines

Fly to

Mexico

Route

Depart

Return

Price

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 2/12

7:32 pm-5:05 pm

1 stop21h 33m

Mexico City Benito Juarez

Thu 2/26

8:10 am-6:42 pm

1 stop10h 32m

$367

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Sun 2/15

6:55 pm-1:23 pm

2 stops18h 28m

Cozumel

Thu 2/19

2:25 pm-10:20 pm

1 stop7h 55m

$409

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Sun 3/1

10:57 am-1:55 pm

2 stops26h 58m

Cozumel

Tue 3/3

3:10 pm-10:17 am

2 stops19h 07m

$414

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Mon 3/2

5:24 am-1:55 pm

1 stop8h 31m

Cozumel

Thu 3/5

3:10 pm-10:17 am

2 stops19h 07m

$414

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sun 1/25

5:35 am-10:24 pm

2 stops15h 49m

Cancun

Fri 1/30

8:00 am-4:28 pm

1 stop9h 28m

$435

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 1/12

6:24 am-2:00 pm

1 stop6h 36m

Cancun

Thu 1/29

3:00 pm-9:24 pm

1 stop7h 24m

$435

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 2/4

11:26 am-9:11 pm

1 stop8h 45m

Cancun

Tue 2/10

8:00 am-4:28 pm

1 stop9h 28m

$435

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 2/3

6:24 am-2:00 pm

1 stop6h 36m

Cancun

Tue 2/10

8:00 am-4:28 pm

1 stop9h 28m

$435

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sun 1/25

5:35 am-8:00 pm

2 stops13h 25m

Cancun

Fri 1/30

11:15 am-10:29 pm

2 stops12h 14m

$435

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Wed 2/25

6:50 am-2:57 pm

1 stop8h 07m

Cozumel

Wed 3/4

3:10 pm-10:17 am

2 stops19h 07m

$438

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/18

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico

What is the cheapest month to book a flight from Des Moines to Mexico?

Currently, October is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $241). Flying from Des Moines to Mexico in June is currently the most expensive (average of $479). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MX?

Find hourly flight availability from Des Moines to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 20, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to Mexico in the evening. If you’re flexible enough to do this you can expect to save up to 7% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated December 20, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,258 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,021 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,100 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Aeromexico
7.4
Good
1,629 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,051 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Mexico?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Mexico?

    United Airlines, Delta, and Aeromexico can get you from Des Moines to Mexico in just under 15h 49m. Your travel time can differ by up to 11h 09m. Airlines will cover a distance of 1470 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Des Moines to Mexico one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $184. Users have also found prices from $240 and $246 on Delta and United Airlines, respectively.

  • What are the most popular routes from Des Moines to Mexico?

    Most travelers choose Des Moines - Cancun, Des Moines - Cozumel or Des Moines - San José del Cabo Los Cabos when deciding on the best route from Des Moines to Mexico.

  • Can I find deals for flights from Des Moines to Mexico that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico.

  • Can I find deals for business class flights from Des Moines to Mexico?

    Yes. Cheapflights offers flight deals from Des Moines to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mexico?

    Currently, October is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $241). Flying from Des Moines to Mexico in June is currently the most expensive (average of $479). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Des Moines to Mexico

Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$250Average$626FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$366Average$678FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$379Average$629FlexibilityNo cancel feeOn-time69%
AeromexicoCheapest$410Average$499FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$547Average$660FlexibilityNo cancel feeOn-time63%

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