Mexico

$142+ Cheap flights from Des Moines (DSM) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/21. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Apr 9 — Apr 161
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Cheap flight deals from Des Moines to Mexico

Cheapest flights from Des Moines to Mexico
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2010:15 am
DSM
-
CUN
1 stop28h 18m
Frontier
Tue 3/2412:16 pm
CUN
-
DSM
2 stops31h 00m
Frontier
Deal found 3/6$375
This FlightHub deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:21 pm
DSM
-
CUN
1 stop14h 55m
Frontier
Wed 3/259:53 am
CUN
-
DSM
1 stop9h 23m
Frontier
Deal found 3/6$380
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:00 am
DSM
-
CUN
1 stop6h 05m
American Airlines
Tue 4/2811:52 am
CUN
-
DSM
1 stop11h 57m
American Airlines
Deal found 3/8$387
This Bravofly deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:44 pm
DSM
-
CUN
2 stops19h 36m
Aeromexico
Tue 4/286:00 am
CUN
-
DSM
2 stops11h 45m
Aeromexico
Deal found 3/7$393
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:59 pm
DSM
-
MEX
2 stops40h 41m
Multiple Airlines
Sun 4/268:40 am
MEX
-
DSM
1 stop27h 29m
Multiple Airlines
Deal found 3/7$397
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:59 pm
DSM
-
MEX
2 stops40h 41m
Multiple Airlines
Thu 4/308:40 am
MEX
-
DSM
1 stop27h 29m
Multiple Airlines
Deal found 3/8$423
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:04 pm
DSM
-
MEX
2 stops32h 26m
Multiple Airlines
Sun 4/268:40 am
MEX
-
DSM
1 stop27h 29m
Multiple Airlines
Deal found 3/8$424
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:00 am
DSM
-
GDL
1 stop8h 30m
Multiple Airlines
Tue 5/197:10 am
GDL
-
DSM
2 stops28h 49m
Multiple Airlines
Deal found 3/9$426
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:56 pm
DSM
-
CUN
1 stop13h 05m
Frontier
Mon 3/2310:08 am
CUN
-
DSM
1 stop9h 08m
Frontier
Deal found 3/6$428
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:59 pm
DSM
-
MTY
1 stop24h 56m
Multiple Airlines
Sun 4/266:00 am
MTY
-
DSM
2 stops30h 09m
Multiple Airlines
Deal found 3/6$430
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/133:20 pm
DSM
-
SJD
1 stop20h 25m
American Airlines
Fri 4/172:59 pm
SJD
-
DSM
1 stop7h 00m
American Airlines
Deal found 3/5$435
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:04 pm
DSM
-
MEX
1 stop28h 26m
Multiple Airlines
Fri 5/16:50 am
MEX
-
DSM
2 stops13h 34m
Multiple Airlines
Deal found 3/10$444

Find flight deals from Des Moines to Mexico

Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated March 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$375
(Kiwi.com)

One-way from

$142
(Trip.com)

Popular in

December

Cheapest in

August

Average price

$549
Provider with most accurate pricing for Des Moines-Mexico City Benito Juarez flight deals.
Provider most trusted by Cheapflights users for Des Moines-Mexico City Benito Juarez flights.
From Des Moines to Mexico
One-way flight from Des Moines to Mexico
Highest demand for flights based on searches. 19% potential increase in price ($154 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesPuerto Vallarta

DSM - PVR

DSMPVR

Des Moines

Mon 4/13

7:05 pm-11:19 am

1 stop17h 14m

Puerto Vallarta Ordaz

Fri 4/17

11:22 am-11:59 pm

1 stop11h 37m

$454

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Fri 5/8

2:33 pm-8:16 pm

1 stop5h 43m

Cancun

Fri 5/15

8:00 am-5:54 pm

1 stop9h 54m

$468

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 5/5

8:15 am-12:48 pm

1 stop6h 33m

San José del Cabo Los Cabos

Tue 5/12

11:32 am-10:45 pm

1 stop9h 13m

$492

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 4/21

5:45 am-4:38 pm

2 stops10h 53m

Cancun

Tue 4/28

8:06 am-10:34 pm

2 stops14h 28m

$492

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Fri 5/1

6:15 am-1:10 pm

1 stop6h 55m

Cancun

Fri 5/8

2:49 pm-10:45 pm

1 stop7h 56m

$492

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 4/24

2:04 pm-5:30 pm

1 stop28h 26m

Mexico City Benito Juarez

Fri 5/1

6:50 am-9:24 pm

2 stops13h 34m

$493

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 4/19

11:00 am-6:30 pm

1 stop8h 30m

Guadalajara Miguel Hidal

Sun 4/26

5:50 am-1:09 pm

2 stops30h 19m

$511

Des MoinesPuerto Vallarta

DSM - PVR

DSMPVR

Des Moines

Tue 4/7

5:30 am-12:53 pm

1 stop8h 23m

Puerto Vallarta Ordaz

Tue 4/14

1:55 pm-11:42 pm

1 stop8h 47m

$512

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Wed 5/6

7:00 am-5:48 pm

2 stops12h 48m

San José del Cabo Los Cabos

Sat 5/9

6:07 am-10:32 pm

2 stops14h 25m

$537

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Wed 4/8

8:20 am-12:48 pm

1 stop6h 28m

San José del Cabo Los Cabos

Sat 4/11

2:50 pm-11:42 pm

1 stop6h 52m

$537

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/7

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Des Moines to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico

What is the cheapest month to book a flight from Des Moines to Mexico?

Currently, October is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $241). Flying from Des Moines to Mexico in June is currently the most expensive (average of $468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated March 10, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Des Moines to Mexico?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Mexico?

    American Airlines, Delta, and United Airlines can get you from Des Moines to Mexico in just under 5h 43m. Your travel time can differ by up to 11h 31m. Airlines will cover a distance of 1470 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Des Moines to Mexico?

  • Can I find deals for flights from Des Moines to Mexico that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico.

  • Can I find deals for business class flights from Des Moines to Mexico?

    Yes. Cheapflights offers flight deals from Des Moines to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mexico?

    Currently, October is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $241). Flying from Des Moines to Mexico in June is currently the most expensive (average of $468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Mexico

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Des Moines to Mexico

Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$233Average$480FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$366Average$651FlexibilityNo cancel feeOn-time71%
DeltaCheapest$373Average$605FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$379Average$651FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$569Average$694FlexibilityNo cancel feeOn-time63%

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