$170+ Cheap flights from Des Moines (DSM) to Mexico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to MexicoExplore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:54 pm -
1 stop24h 00m
Fri 9/1810:37 am -
1 stop8h 11m
Deal found 8/6![Multiple Airlines logo]()
$437
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:54 pm -
1 stop24h 00m
Thu 9/1710:37 am -
1 stop9h 29m
Deal found 8/8![Multiple Airlines logo]()
$442
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:31 pm -
1 stop22h 46m
Mon 9/288:22 pm -
2 stops40h 30m
Deal found 8/7![Multiple Airlines logo]()
$454
This Priceline deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:30 pm -
2 stops26h 45m
Mon 9/288:40 am -
1 stop9h 53m
Deal found 8/8![Frontier logo]()
$462
This FlightHub deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:30 pm -
2 stops30h 09m
Tue 10/207:58 am -
1 stop28h 20m
Deal found 8/9![Frontier logo]()
$464
This Frontier deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:19 pm -
1 stop10h 51m
Mon 9/146:16 am -
2 stops12h 17m
Deal found 8/6![Frontier logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:31 pm -
2 stops23h 29m
Mon 9/288:40 am -
1 stop9h 53m
Deal found 8/7![Multiple Airlines logo]()
$469
This FlightHub deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:31 pm -
1 stop26h 54m
Mon 10/198:46 am -
2 stops51h 32m
Deal found 8/9![Frontier logo]()
$471
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:54 pm -
1 stop24h 00m
Wed 9/167:58 am -
1 stop25h 46m
Deal found 8/6![Multiple Airlines logo]()
$472
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:00 am -
1 stop8h 10m
Fri 9/186:00 am -
2 stops12h 48m
Deal found 8/9![Multiple Airlines logo]()
$472
This Frontier deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:19 pm -
1 stop10h 51m
Sun 9/208:50 pm -
2 stops21h 43m
Deal found 8/8![Frontier logo]()
$479
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:00 am -
2 stops24h 30m
Thu 9/1710:37 am -
1 stop9h 29m
Deal found 8/8![Multiple Airlines logo]()
$482
Best flights from Des Moines to MexicoDiscover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from Des Moines to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:31 pm -
1 stop22h 46m
Mon 9/288:22 pm -
2 stops40h 30m
Deal found 8/7![Multiple Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/234:14 pm -
1 stop5h 26m
Wed 9/304:42 pm -
1 stop5h 30m
Deal found 8/9![American Airlines logo]()
$567
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/165:15 pm -
1 stop16h 45m
Fri 1/221:40 pm -
1 stop8h 12m
Deal found 8/5![Delta logo]()
$568
This FlightHub deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:30 pm -
2 stops26h 45m
Fri 10/27:00 am -
2 stops11h 33m
Deal found 8/5![Frontier logo]()
$581
This lastminute.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:45 am -
2 stops19h 08m
Sat 9/269:24 am -
2 stops12h 02m
Deal found 8/5![Aeromexico logo]()
$589
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:15 am -
1 stop6h 44m
Thu 12/102:55 pm -
1 stop7h 22m
Deal found 8/6![United Airlines logo]()
$593
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:40 am -
1 stop6h 20m
Mon 9/281:05 pm -
1 stop9h 10m
Deal found 8/7![Southwest logo]()
$598
This Kissandfly.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/205:21 pm -
2 stops25h 52m
Sun 9/276:50 am -
2 stops15h 45m
Deal found 8/6![Lufthansa logo]()
$773
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:31 pm -
1 stop25h 14m
Mon 9/288:40 am -
1 stop9h 53m
Deal found 8/7![Multiple Airlines logo]()
$524
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:21 am -
2 stops9h 49m
Wed 11/258:00 am -
1 stop7h 13m
Deal found 8/9![Delta logo]()
$573
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/234:14 pm -
1 stop6h 46m
Wed 9/306:13 am -
1 stop7h 57m
Deal found 8/9![American Airlines logo]()
$592
This Aeromexico deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:45 am -
1 stop11h 55m
Thu 10/112:16 pm -
1 stop9h 10m
Deal found 8/6![Aeromexico logo]()
$597
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/208:00 am -
1 stop6h 42m
Mon 1/254:50 pm -
1 stop6h 40m
Deal found 8/9![United Airlines logo]()
$600
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:42 pm -
1 stop30h 23m
Sun 10/45:35 am -
2 stops15h 22m
Deal found 8/5![Multiple Airlines logo]()
$553
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:35 am -
1 stop7h 05m
Tue 10/133:20 pm -
1 stop6h 35m
Deal found 8/5![Southwest logo]()
$613
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
2 stops13h 55m
Fri 11/138:00 am -
2 stops13h 50m
Deal found 8/10![Delta logo]()
$573
This Aeromexico deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:55 am -
2 stops11h 32m
Tue 10/136:03 am -
2 stops15h 30m
Deal found 8/6![Aeromexico logo]()
$598
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/35:15 am -
1 stop6h 50m
Sun 1/1012:10 pm -
2 stops10h 25m
Deal found 8/8![Southwest logo]()
$614
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/58:00 am -
1 stop6h 30m
Mon 2/83:11 pm -
1 stop8h 50m
Deal found 8/5![United Airlines logo]()
$618
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:22 pm -
1 stop17h 37m
Wed 9/3012:24 pm -
1 stop9h 48m
Deal found 8/9![American Airlines logo]()
$628
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:30 am -
1 stop9h 00m
Fri 12/46:06 am -
2 stops12h 59m
Deal found 8/6![Delta logo]()
$593
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:38 pm -
1 stop26h 07m
Mon 8/318:10 am -
2 stops10h 54m
Deal found 8/5![Multiple Airlines logo]()
$601
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/135:55 am -
2 stops8h 30m
Thu 1/142:55 pm -
1 stop7h 40m
Deal found 8/7![Southwest logo]()
$618
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:27 pm -
1 stop16h 57m
Wed 11/114:51 pm -
1 stop6h 14m
Deal found 8/5![American Airlines logo]()
$629
This Aeromexico deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:30 am -
2 stops17h 10m
Mon 11/169:20 pm -
2 stops20h 45m
Deal found 8/5![Aeromexico logo]()
$635
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:22 pm -
2 stops8h 48m
Wed 9/302:15 pm -
1 stop7h 00m
Deal found 8/10![United Airlines logo]()
$635
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/235:45 am -
2 stops13h 15m
Wed 1/278:15 am -
2 stops14h 09m
Deal found 8/8![Delta logo]()
$598
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:00 am -
2 stops8h 50m
Wed 11/181:05 pm -
1 stop6h 40m
Deal found 8/6![Southwest logo]()
$620
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
1 stop7h 29m
Fri 11/203:51 pm -
2 stops17h 24m
Deal found 8/8![American Airlines logo]()
$634
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:45 am -
2 stops8h 58m
Mon 9/2811:47 am -
2 stops11h 01m
Deal found 8/7![United Airlines logo]()
$638
Last-minute flights from Des Moines to MexicoDiscover last-minute flight deals from Des Moines to Mexico. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Mexico. Data last updated August 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:54 pm -
1 stop24h 00m
Fri 9/1810:37 am -
1 stop8h 11m
Deal found 8/6![Multiple Airlines logo]()
$437
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:54 pm -
1 stop24h 00m
Thu 9/1710:37 am -
1 stop9h 29m
Deal found 8/8![Multiple Airlines logo]()
$442
This Frontier deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:19 pm -
1 stop10h 51m
Mon 9/146:16 am -
2 stops12h 17m
Deal found 8/6![Frontier logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:54 pm -
1 stop24h 00m
Wed 9/167:58 am -
1 stop25h 46m
Deal found 8/6![Multiple Airlines logo]()
$472
This Frontier deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:19 pm -
1 stop10h 51m
Sun 9/208:50 pm -
2 stops21h 43m
Deal found 8/8![Frontier logo]()
$479
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:00 am -
2 stops24h 30m
Thu 9/1710:37 am -
1 stop9h 29m
Deal found 8/8![Multiple Airlines logo]()
$482
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
2 stops35h 46m
Mon 9/148:40 am -
1 stop9h 53m
Deal found 8/7![Multiple Airlines logo]()
$490
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:00 am -
1 stop8h 10m
Fri 9/186:00 am -
2 stops12h 48m
Deal found 8/9![Multiple Airlines logo]()
$472
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:31 pm -
1 stop22h 46m
Mon 9/288:22 pm -
2 stops40h 30m
Deal found 8/7![Multiple Airlines logo]()
$454
This Priceline deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:30 pm -
2 stops26h 45m
Mon 9/288:40 am -
1 stop9h 53m
Deal found 8/8![Frontier logo]()
$462
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:31 pm -
2 stops23h 29m
Mon 9/288:40 am -
1 stop9h 53m
Deal found 8/7![Multiple Airlines logo]()
$469
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:31 pm -
1 stop23h 34m
Fri 10/28:40 am -
1 stop9h 53m
Deal found 8/5![Multiple Airlines logo]()
$494
One-way flights from Des Moines to MexicoSearch for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from Des Moines to Mexico. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1712:37 pm -
3 stops34h 59m
Deal found 8/8![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1712:37 pm -
1 stop10h 38m
Deal found 8/5![Multiple Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/133:15 pm -
1 stop31h 30m
Deal found 8/9![Multiple Airlines logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:19 pm -
1 stop28h 11m
Deal found 8/6![Multiple Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/153:27 pm -
2 stops31h 28m
Deal found 8/9![Multiple Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:15 am -
2 stops29h 54m
Deal found 8/10![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm -
2 stops43h 20m
Deal found 8/8![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:30 pm -
2 stops27h 28m
Deal found 8/7![Multiple Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:53 pm -
3 stops34h 07m
Deal found 8/5![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/169:44 pm -
1 stop21h 36m
Deal found 8/8![Multiple Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/196:00 am -
1 stop7h 03m
Deal found 8/7![United Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:53 pm -
1 stop29h 15m
Deal found 8/8![Multiple Airlines logo]()
$276
Find flight deals from Des Moines to Mexico
Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $437 (Kiwi.com) |
One-way from | $170 (Kiwi.com) |
Popular in | December |
Cheapest in | March |
Average price | $628 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesMonterrey
DSM Des Moines - MTY Monterrey Gen Mariano Escobedo
DSMMTY
Des Moines
Mon 9/21
9:31 pm-7:17 pm
1 stop22h 46m
Monterrey Gen Mariano Escobedo
Mon 9/28
8:22 pm-1:52 pm
2 stops40h 30m
$454
Des MoinesMexico City
DSM Des Moines - MEX Mexico City Benito Juarez
DSMMEX
Des Moines
Mon 9/21
9:31 pm-9:45 pm
1 stop25h 14m
Mexico City Benito Juarez
Mon 9/28
8:40 am-7:33 pm
1 stop9h 53m
$524
Des MoinesMexico City
DSM Des Moines - MEX Mexico City Benito Juarez
DSMMEX
Des Moines
Wed 9/30
2:42 pm-8:05 pm
1 stop30h 23m
Mexico City Benito Juarez
Sun 10/4
5:35 am-9:57 pm
2 stops15h 22m
$553
Quickest round-trip
Des MoinesMonterrey
DSM Des Moines - MTY Monterrey Gen Mariano Escobedo
DSMMTY
Des Moines
Wed 9/23
4:14 pm-8:40 pm
1 stop5h 26m
Monterrey Gen Mariano Escobedo
Wed 9/30
4:42 pm-11:12 pm
1 stop5h 30m
$567
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Sat 1/16
5:15 pm-11:00 am
1 stop16h 45m
Cancun
Fri 1/22
1:40 pm-8:52 pm
1 stop8h 12m
$568
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Wed 11/18
10:21 am-9:10 pm
2 stops9h 49m
Cancun
Wed 11/25
8:00 am-2:13 pm
1 stop7h 13m
$573
Des MoinesCancún
DSM Des Moines - CUN Cancun
DSMCUN
Des Moines
Sun 11/8
6:00 am-8:55 pm
2 stops13h 55m
Cancun
Fri 11/13
8:00 am-8:50 pm
2 stops13h 50m
$573
Des MoinesMexico City
DSM Des Moines - MEX Mexico City Benito Juarez
DSMMEX
Des Moines
Mon 9/28
8:30 pm-10:15 pm
2 stops26h 45m
Mexico City Benito Juarez
Fri 10/2
7:00 am-7:33 pm
2 stops11h 33m
$581
Des MoinesMérida
DSM Des Moines - MID Mérida Rejon
DSMMID
Des Moines
Sat 9/19
5:45 am-11:53 pm
2 stops19h 08m
Mérida Rejon
Sat 9/26
9:24 am-10:26 pm
2 stops12h 02m
$589
Des MoinesGuadalajara
DSM Des Moines - GDL Guadalajara Miguel Hidal
DSMGDL
Des Moines
Wed 9/23
4:14 pm-10:00 pm
1 stop6h 46m
Guadalajara Miguel Hidal
Wed 9/30
6:13 am-3:10 pm
1 stop7h 57m
$592
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
DSM-MTY
DSM-CUN
DSM-MEX
DSM-MID
DSM-MLM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Mexico
DSM-MX0
DSM-MTY
DSM-CUN
DSM-MEX
DSM-MID
What is the cheapest month to book a flight from Des Moines to Mexico?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $570). Flying from Des Moines to Mexico in December is currently the most expensive (average of $781). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Des Moines to Mexico?
Booking 16 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Mexico. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Mexico
Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated August 10, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Mexico
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Complete your trip
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Find flights from Des Moines to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Mexico flights
Browse other Des Moines and Mexico flight options. Last updated on August 10, 2026.
Popular flight searches
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Des Moines to Mexico flights
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Consider these flights traveling to Mexico regions.
Top 5 airlines flying from Des Moines to Mexico
Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$494 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$423 | Average$676 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$441 | Average$706 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$465 | Average$738 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$569 | Average$700 | FlexibilityNo cancel fee | On-time63% |