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$184+ Cheap flights from Des Moines (DSM) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Find flight deals from Des Moines to Mexico

Cheapest flights from Des Moines to Mexico
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2810:00 amDSM - CUN
1 stop22h 13mMultiple Airlines
Wed 12/36:02 pmCUN - DSM
2 stops43h 53mMultiple Airlines
Deal found 11/5$403
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:56 pmDSM - CUN
1 stop21h 17mMultiple Airlines
Sun 12/74:18 amCUN - DSM
2 stops15h 45mMultiple Airlines
Deal found 11/6$415
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:29 pmDSM - CUN
2 stops36h 54mFrontier
Fri 12/264:58 pmCUN - DSM
1 stop27h 46mFrontier
Deal found 11/5$428
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2810:00 amDSM - CUN
1 stop22h 13mMultiple Airlines
Sat 12/62:36 pmCUN - DSM
2 stops32h 00mMultiple Airlines
Deal found 11/5$437
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:53 pmDSM - CUN
1 stop17h 42mMultiple Airlines
Sun 12/74:18 amCUN - DSM
2 stops15h 45mMultiple Airlines
Deal found 11/3$443
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/163:38 pmDSM - CZM
1 stop22h 12mAmerican Airlines
Tue 12/233:05 pmCZM - DSM
1 stop19h 42mAmerican Airlines
Deal found 11/3$451
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/72:56 pmDSM - CUN
1 stop21h 17mMultiple Airlines
Sat 12/1311:50 amCUN - DSM
2 stops35h 56mMultiple Airlines
Deal found 11/6$452
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:32 pmDSM - GDL
1 stop25h 53mMultiple Airlines
Tue 12/28:20 pmGDL - DSM
2 stops43h 11mMultiple Airlines
Deal found 11/4$483
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:00 pmDSM - MTY
1 stop20h 22mAmerican Airlines
Thu 12/253:07 pmMTY - DSM
1 stop8h 28mAmerican Airlines
Deal found 11/3$497
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:00 amDSM - CZM
1 stop8h 36mAmerican Airlines
Fri 12/193:01 pmCZM - DSM
1 stop8h 57mAmerican Airlines
Deal found 11/4$499
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:50 pmDSM - CZM
2 stops18h 33mUnited Airlines
Wed 12/172:25 pmCZM - DSM
2 stops20h 25mUnited Airlines
Deal found 11/6$503
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:53 pmDSM - CZM
1 stop22h 30mUnited Airlines
Wed 12/102:25 pmCZM - DSM
1 stop8h 04mUnited Airlines
Deal found 11/5$509

Cheap flight deals from Des Moines to Mexico

Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$378
(Kiwi.com)

One-way from

$184
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$598
Provider with most accurate pricing for Des Moines-Mexico City Benito Juarez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Mexico City Benito Juarez flights.
Search Deals
From Des Moines to Mexico
Search Deals
One-way flight from Des Moines to Mexico
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($140 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.

Fly from

Des Moines

Fly to

Mexico

Route

Depart

Return

Price

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Mon 1/12

5:09 pm-1:23 pm

2 stops20h 14m

Cozumel

Wed 1/28

2:25 pm-12:52 pm

2 stops22h 27m

$455

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 1/23

8:30 am-8:35 pm

1 stop12h 05m

Guadalajara Miguel Hidal

Sat 2/7

6:08 am-3:03 pm

2 stops32h 55m

$460

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Fri 1/23

11:09 am-9:13 am

2 stops21h 04m

Cancun

Sun 2/1

1:21 pm-10:46 pm

1 stop10h 25m

$476

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 11/10

2:32 pm-4:25 pm

1 stop25h 53m

Guadalajara Miguel Hidal

Tue 12/2

8:20 pm-3:31 pm

2 stops43h 11m

$483

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Fri 1/16

4:00 pm-2:24 pm

1 stop22h 24m

Cozumel

Wed 1/21

3:24 pm-11:23 pm

1 stop7h 59m

$485

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 1/27

6:54 am-6:47 pm

2 stops10h 53m

Cancun

Tue 2/3

12:15 pm-10:31 pm

1 stop11h 16m

$487

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 12/1

5:35 am-3:34 pm

1 stop8h 59m

Cancun

Mon 12/8

7:53 pm-5:47 pm

2 stops22h 54m

$487

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 1/26

8:10 am-5:50 pm

1 stop8h 40m

Cancun

Fri 1/30

2:44 pm-10:30 pm

1 stop8h 46m

$487

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 1/6

6:54 am-3:25 pm

1 stop7h 31m

Cancun

Tue 4/7

8:00 am-4:30 pm

1 stop8h 30m

$487

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sat 1/3

6:30 pm-10:15 am

1 stop14h 45m

Cancun

Tue 4/7

8:00 am-10:28 pm

1 stop14h 28m

$487

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico

What is the cheapest month to book a flight from Des Moines to Mexico?

Currently, October is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $244). Flying from Des Moines to Mexico in June is currently the most expensive (average of $472). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MX?

Find hourly flight availability from Des Moines to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to Mexico in the evening. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Des Moines to Mexico?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Mexico. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Des Moines to Mexico flight should consider departing on Sunday afternoons when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated November 6, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,240 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,001 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,003 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Aeromexico
7.4
Good
1,672 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,040 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Mexico?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Mexico?

    United Airlines, American Airlines, and Delta can get you from Des Moines to Mexico in just under 10h 53m. Your travel time can differ by up to 11h 31m. Airlines will cover a distance of 1470 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Des Moines to Mexico one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $230. Users have also found prices from $255 and $261 on American Airlines and United Airlines, respectively.

  • What are the most popular routes from Des Moines to Mexico?

    Most travelers choose Des Moines - Cancun, Des Moines - Cozumel or Des Moines - San José del Cabo Los Cabos when deciding on the best route from Des Moines to Mexico.

  • Can I find deals for flights from Des Moines to Mexico that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico.

  • Can I find deals for business class flights from Des Moines to Mexico?

    Yes. Cheapflights offers flight deals from Des Moines to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mexico?

    Currently, October is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $244). Flying from Des Moines to Mexico in June is currently the most expensive (average of $472). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Des Moines to Mexico

Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$250Average$610FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$379Average$642FlexibilityNo cancel feeOn-time69%
AeromexicoCheapest$410Average$514FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$420Average$652FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$547Average$655FlexibilityNo cancel feeOn-time63%

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