How long is the flight from Indianapolis to Florence, South Carolina?

Airlines like American Airlines fly from Indianapolis to Florence, South Carolina in about 4h 14m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 526 mi.

In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from IND to FLO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Indianapolis to Florence, South Carolina as you normally would.

Most accurate provider : When it comes to deals on Indianapolis-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Indianapolis-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Indianapolis-Florence, South Carolina flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Indianapolis-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Indianapolis to Florence that include hotel bookings?

Yes. In addition to deals on Indianapolis to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Indianapolis to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Florence.

Can I find deals for business class flights from Indianapolis to Florence?

Yes. Cheapflights offers flight deals from Indianapolis to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$973+ Cheap Flights from Indianapolis to Florence, SC

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Cheap flight deals from Indianapolis to Florence

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Best flights from Indianapolis to Florence
Discover carefully curated flight deals from Indianapolis to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 2, 2026.

Wed 3/2410:56 am -

1 stop4h 14m

Fri 3/262:33 pm -

1 stop21h 02m

Deal found 10/30

$973

Find flight deals from Indianapolis to Florence

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$973 (American Airlines)

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IndianapolisFlorence

IND Indianapolis - FLO Florence

INDFLO

Indianapolis

Wed 3/24

10:56 am-3:10 pm

1 stop4h 14m

Florence

Fri 3/26

2:33 pm-11:35 am

1 stop21h 02m

$973

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Deals found on 10/30

Sorted by cheapest first

Compare providers for flights from Indianapolis to Florence

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Florence in November.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy2 stars	Trust Score*3 stars
Expedia	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Indianapolis-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Indianapolis-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Indianapolis-Florence, South Carolina flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Indianapolis-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Indianapolis with our price prediction graph.

IND-FLO

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Indianapolis to Florence, South Carolina?
Airlines like American Airlines fly from Indianapolis to Florence, South Carolina in about 4h 14m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 526 mi.
Can I find deals for flights from Indianapolis to Florence that include hotel bookings?
Yes. In addition to deals on Indianapolis to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Indianapolis to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Florence.
Can I find deals for business class flights from Indianapolis to Florence?
Yes. Cheapflights offers flight deals from Indianapolis to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$973+ Cheap flights from Indianapolis to Florence, SC (IND - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Indianapolis to Florence with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Indianapolis to Florence

Best flights from Indianapolis to FlorenceDiscover carefully curated flight deals from Indianapolis to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 2, 2026.

Discover carefully curated flight deals from Indianapolis to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 2, 2026.

Find flight deals from Indianapolis to Florence

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Use the filters below to find and compare flights from Indianapolis to Florence that are best for you.

Compare providers for flights from Indianapolis to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Florence in November.

Best time to book a flight from Indianapolis to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Indianapolis with our price prediction graph.

Related info for your journey

How long is the flight from Indianapolis to Florence, South Carolina?

Can I find deals for flights from Indianapolis to Florence that include hotel bookings?

How can I find direct flights from Indianapolis to Florence?

Can I find deals for business class flights from Indianapolis to Florence?

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Other flights to Florence

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Best flights from Indianapolis to Florence
Discover carefully curated flight deals from Indianapolis to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 2, 2026.