$245+ Cheap flights from Florence, SC to Indianapolis (FLO - IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — IND
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Florence to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Florence to Indianapolis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Florence to IndianapolisExplore the most affordable flight options available from Florence to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Florence to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:24 am -
1 stop4h 02m
Sat 11/146:32 pm -
1 stop4h 27m
Deal found 10/26![American Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:09 am -
1 stop4h 16m
Mon 11/96:32 pm -
1 stop4h 27m
Deal found 10/27![American Airlines logo]()
$555
Best flights from Florence to IndianapolisDiscover carefully curated flight deals from Florence to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Florence to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:24 am -
1 stop4h 02m
Sat 11/146:32 pm -
1 stop4h 27m
Deal found 10/26![American Airlines logo]()
$489
Last-minute flights from Florence to IndianapolisDiscover last-minute flight deals from Florence to Indianapolis. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Florence to Indianapolis. Data last updated October 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:09 am -
1 stop4h 16m
Mon 11/96:32 pm -
1 stop4h 27m
Deal found 10/27![American Airlines logo]()
$555
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:24 am -
1 stop4h 02m
Sat 11/146:32 pm -
1 stop4h 27m
Deal found 10/26![American Airlines logo]()
$489
One-way flights from Florence to IndianapolisSearch for one-way flight options from Florence to Indianapolis. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Florence to Indianapolis. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/212:35 pm -
1 stop4h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![American Airlines logo]()
$245
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:09 am -
1 stop4h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![American Airlines logo]()
$499
Find flight deals from Florence to Indianapolis
Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Indianapolis (IND). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $489 (American Airlines) |
One-way from | $245 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Florence to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
FlorenceIndianapolis
FLO Florence - IND Indianapolis
FLOIND
Florence
Sat 11/21
2:35 pm-7:13 pm
1 stop4h 38m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$245
FlorenceIndianapolis
FLO Florence - IND Indianapolis
FLOIND
Florence
Tue 11/10
6:24 am-10:26 am
1 stop4h 02m
Indianapolis
Sat 11/14
6:32 pm-10:59 pm
1 stop4h 27m
$489
Quickest round-trip
FlorenceIndianapolis
FLO Florence - IND Indianapolis
FLOIND
Florence
Fri 11/20
5:09 am-9:27 am
1 stop4h 18m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$499
Sorted by cheapest first
Compare providers for flights from Florence to Indianapolis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to Indianapolis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Florence, South Carolina-Indianapolis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Indianapolis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Indianapolis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Florence, South Carolina-Indianapolis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Indianapolis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Florence to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Florence with our price prediction graph.
FLO-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Florence to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsPlainfield
Greenwood
Terre Haute
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Carmel
Bloomington
Noblesville
Speedway
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