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$278+ Cheap flights from Des Moines to Columbia (DSM - CAE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CAE
May 24 — May 311
Sun 5/24
Sun 5/31
1 adult, Economy
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Cheap flight deals from Des Moines to Columbia

Cheapest flights from Des Moines to Columbia
Explore the most affordable flight options available from Des Moines to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2211:23 am
DSM
-
CAE
1 stop4h 47m
United Airlines
Sat 8/292:29 pm
CAE
-
DSM
1 stop5h 55m
United Airlines
Deal found 4/21$285
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:00 am
DSM
-
CAE
1 stop7h 46m
United Airlines
Tue 7/75:40 pm
CAE
-
DSM
1 stop5h 00m
United Airlines
Deal found 4/22$326
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:41 pm
DSM
-
CAE
1 stop4h 08m
Delta
Mon 5/187:17 pm
CAE
-
DSM
1 stop4h 15m
Delta
Deal found 4/23$329
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:41 pm
DSM
-
CAE
1 stop4h 05m
Delta
Mon 6/17:17 pm
CAE
-
DSM
1 stop4h 15m
Delta
Deal found 4/22$362
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:48 pm
DSM
-
CAE
1 stop5h 45m
American Airlines
Sun 5/247:03 pm
CAE
-
DSM
1 stop5h 47m
American Airlines
Deal found 4/21$364
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
DSM
-
CAE
1 stop7h 12m
United Airlines
Tue 8/256:30 am
CAE
-
DSM
1 stop4h 41m
United Airlines
Deal found 4/19$365
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:41 pm
DSM
-
CAE
1 stop4h 08m
Delta
Mon 5/257:17 pm
CAE
-
DSM
1 stop4h 15m
Delta
Deal found 4/18$379

Find flight deals from Des Moines to Columbia

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Columbia (CAE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$285
(United Airlines)

One-way from

$278
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$361
Provider with most accurate pricing for Des Moines-Columbia Metropolitan flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Columbia Metropolitan flights.
Search Deals
From Des Moines to Columbia Metropolitan
Search Deals
One-way flight from Des Moines to Columbia Metropolitan
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Des Moines to Columbia that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sat 8/22

5:00 am-2:10 pm

2 stops8h 10m

Columbia Metropolitan

Sat 8/29

2:29 pm-9:12 pm

1 stop7h 43m

$290

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Thu 7/2

5:00 am-1:46 pm

1 stop7h 46m

Columbia Metropolitan

Tue 7/7

5:40 pm-9:40 pm

1 stop5h 00m

$326
Quickest round-trip

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sat 8/22

6:00 am-2:12 pm

1 stop7h 12m

Columbia Metropolitan

Tue 8/25

6:30 am-10:11 am

1 stop4h 41m

$365

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sat 8/22

6:00 am-2:12 pm

1 stop7h 12m

Columbia Metropolitan

Wed 8/26

6:30 am-10:11 am

1 stop4h 41m

$365

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Wed 5/27

6:00 am-2:16 pm

2 stops7h 16m

Columbia Metropolitan

Mon 6/1

5:27 pm-9:40 pm

1 stop5h 13m

$370
Cheapest one-way

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Fri 5/22

4:48 pm-11:33 pm

1 stop5h 45m

$279

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Fri 5/15

3:30 pm-11:59 pm

2 stops7h 29m

$284

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sun 5/24

6:02 am-2:05 pm

2 stops7h 03m

$315
Quickest one-way

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Fri 5/22

11:23 am-4:52 pm

1 stop4h 29m

$328

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Wed 5/13

8:00 am-1:41 pm

1 stop4h 41m

$364

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/20

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Columbia

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Columbia in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Columbia flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Columbia flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Columbia flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Columbia flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Columbia flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Columbia

Have a flexible travel schedule? Discover the best time to fly to Columbia from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Columbia

How much does it cost to fly round-trip from Des Moines to Columbia?

Reviews of airlines servicing Columbia

Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated April 24, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Des Moines to Columbia. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,450 reviews

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,450 reviews
Delta
7.9
Good
8,450 reviews

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,666 reviews
Delta
7.9
Good
8,450 reviews

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Columbia?

    A quick flight from Des Moines to Columbia can take about 8h 10m. United Airlines provides one of the quickest options available for as low as $290. There are 861 mi between Des Moines and Columbia.

  • What are the cheapest airlines flying from Des Moines to Columbia round-trip?

    Currently priced at $248, American Airlines will fly you from Des Moines to Columbia and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $248. American Airlines is 29% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Des Moines to Columbia that include hotel bookings?

    Yes. In addition to deals on Des Moines to Columbia flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Columbia?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Columbia.

  • Can I find deals for business class flights from Des Moines to Columbia?

    Yes. Cheapflights offers flight deals from Des Moines to Columbia by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Columbia?

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Top 2 airlines flying from Des Moines to Columbia

Discover the top 2 airlines that operate flights from Des Moines to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$353FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$401FlexibilityNo cancel feeOn-timeN/A

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