$284+ Cheap flights from Des Moines to Columbia (DSM - CAE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CAE
Oct 29 — Nov 51
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Columbia with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Columbia
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Cheapest flights from Des Moines to ColumbiaExplore the most affordable flight options available from Des Moines to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
Explore the most affordable flight options available from Des Moines to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:25 pm -
1 stop6h 58m
Sat 12/55:28 pm -
1 stop7h 02m
Deal found 9/29![American Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:26 pm -
1 stop8h 12m
Thu 10/228:30 pm -
1 stop4h 28m
Deal found 9/26![American Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:59 pm -
1 stop4h 11m
Sun 11/225:35 am -
1 stop6h 09m
Deal found 9/27![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:45 am -
1 stop6h 29m
Sat 10/36:09 pm -
1 stop5h 17m
Deal found 9/29![Delta logo]()
$389
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:30 pm -
1 stop4h 38m
Sat 10/36:25 am -
2 stops8h 34m
Deal found 9/29![American Airlines logo]()
$410
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:52 pm -
1 stop4h 01m
Sun 11/225:35 am -
1 stop6h 09m
Deal found 9/24![Delta logo]()
$419
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:26 pm -
1 stop8h 12m
Sun 10/188:30 pm -
1 stop4h 28m
Deal found 9/24![American Airlines logo]()
$430
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:30 am -
2 stops7h 38m
Sat 10/38:18 am -
2 stops8h 23m
Deal found 9/28![American Airlines logo]()
$431
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:23 am -
1 stop7h 51m
Sun 11/224:11 pm -
2 stops9h 08m
Deal found 9/27![American Airlines logo]()
$443
Best flights from Des Moines to ColumbiaDiscover carefully curated flight deals from Des Moines to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
Discover carefully curated flight deals from Des Moines to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/147:00 pm -
1 stop4h 35m
Sat 2/2010:20 am -
2 stops11h 21m
Deal found 9/27![United Airlines logo]()
$332
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/296:30 pm -
1 stop5h 11m
Sat 2/1310:20 am -
1 stop5h 47m
Deal found 9/28![United Airlines logo]()
$427
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:27 am -
1 stop4h 30m
Sat 10/1710:23 am -
2 stops8h 25m
Deal found 9/28![United Airlines logo]()
$474
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/98:00 am -
1 stop4h 51m
Tue 1/122:27 pm -
1 stop6h 43m
Deal found 9/26![United Airlines logo]()
$486
Last-minute flights from Des Moines to ColumbiaDiscover last-minute flight deals from Des Moines to Columbia. Data last updated September 29, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Columbia. Data last updated September 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:30 am -
2 stops7h 38m
Sat 10/38:18 am -
2 stops8h 23m
Deal found 9/28![American Airlines logo]()
$431
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:45 am -
1 stop6h 29m
Sat 10/36:09 pm -
1 stop5h 17m
Deal found 9/29![Delta logo]()
$389
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:30 pm -
1 stop4h 38m
Sat 10/36:25 am -
2 stops8h 34m
Deal found 9/29![American Airlines logo]()
$410
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:45 am -
1 stop6h 29m
Sun 10/41:59 pm -
1 stop5h 10m
Deal found 9/25![Delta logo]()
$454
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:27 am -
1 stop4h 30m
Sat 10/1710:29 am -
1 stop4h 46m
Deal found 9/28![United Airlines logo]()
$469
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:26 pm -
1 stop8h 12m
Sun 10/188:30 pm -
1 stop4h 28m
Deal found 9/24![American Airlines logo]()
$430
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:26 pm -
1 stop8h 12m
Thu 10/228:30 pm -
1 stop4h 28m
Deal found 9/26![American Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:29 am -
1 stop15h 30m
Mon 10/268:30 pm -
1 stop4h 28m
Deal found 9/24![American Airlines logo]()
$462
One-way flights from Des Moines to ColumbiaSearch for one-way flight options from Des Moines to Columbia. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
Search for one-way flight options from Des Moines to Columbia. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:59 pm -
1 stop4h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Delta logo]()
$284
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
2 stops10h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![United Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:35 am -
1 stop6h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Delta logo]()
$320
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:27 am -
1 stop3h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am -
2 stops7h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![United Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
2 stops7h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![United Airlines logo]()
$390
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:27 am -
1 stop4h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/168:00 am -
1 stop8h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![United Airlines logo]()
$442
Find flight deals from Des Moines to Columbia
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Columbia (CAE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $315 (American Airlines) |
One-way from | $284 (Delta) |
Popular in | July |
Cheapest in | January |
Average price | $425 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
Use the filters below to find and compare flights from Des Moines to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Wed 11/18
2:59 pm-8:10 pm
1 stop4h 11m
Columbia Metropolitan
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$284
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Thu 10/22
5:35 am-1:14 pm
1 stop6h 39m
Columbia Metropolitan
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$320
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Sun 2/14
7:00 pm-12:35 am
1 stop4h 35m
Columbia Metropolitan
Sat 2/20
10:20 am-8:41 pm
2 stops11h 21m
$332
Quickest round-trip
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Sat 10/10
11:27 am-4:26 pm
1 stop3h 59m
Columbia Metropolitan
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$369
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Thu 10/22
6:00 am-2:26 pm
2 stops7h 26m
Columbia Metropolitan
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$390
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Fri 1/29
6:30 pm-12:41 am
1 stop5h 11m
Columbia Metropolitan
Sat 2/13
10:20 am-3:07 pm
1 stop5h 47m
$427
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Thu 10/8
11:27 am-4:57 pm
1 stop4h 30m
Columbia Metropolitan
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$429
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Wed 12/16
8:00 am-5:09 pm
1 stop8h 09m
Columbia Metropolitan
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$442
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Tue 10/13
11:27 am-4:57 pm
1 stop4h 30m
Columbia Metropolitan
Sat 10/17
10:23 am-5:48 pm
2 stops8h 25m
$474
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Sat 1/9
8:00 am-1:51 pm
1 stop4h 51m
Columbia Metropolitan
Tue 1/12
2:27 pm-8:10 pm
1 stop6h 43m
$486
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Columbia
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Columbia in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Columbia flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Columbia flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Columbia flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Columbia flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Columbia flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from Des Moines with our price prediction graph.
DSM-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Columbia
Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated September 29, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Des Moines to Columbia. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Entertainment
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Entertainment
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Entertainment
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsIrmo
West Columbia
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Des Moines and Columbia flights
Browse other Des Moines and Columbia flight options. Last updated on September 29, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Des Moines to Columbia
Discover the top 3 airlines that operate flights from Des Moines to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$274 | Average$343 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$308 | Average$577 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$311 | Average$425 | FlexibilityNo cancel fee | On-time71% |