$274+ Cheap flights from Des Moines to Columbia (DSM - CAE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CAE
Oct 1 — Oct 81
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Columbia with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Columbia
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Best
Last-minute
One-way
Cheapest flights from Des Moines to ColumbiaExplore the most affordable flight options available from Des Moines to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
Explore the most affordable flight options available from Des Moines to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:45 am -
1 stop6h 29m
Sat 10/105:11 pm -
1 stop6h 22m
Deal found 8/29![Delta logo]()
$295
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:27 am -
1 stop4h 30m
Tue 10/2710:37 am -
2 stops10h 59m
Deal found 8/28![United Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:56 pm -
1 stop5h 07m
Sat 10/38:18 am -
1 stop4h 46m
Deal found 8/31![American Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:35 am -
1 stop4h 08m
Sun 10/185:59 pm -
1 stop5h 34m
Deal found 8/27![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:34 pm -
1 stop5h 34m
Wed 9/164:10 pm -
1 stop4h 38m
Deal found 8/28![American Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:24 am -
2 stops11h 43m
Wed 9/166:25 am -
1 stop5h 06m
Deal found 8/28![United Airlines logo]()
$327
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:45 am -
1 stop4h 27m
Sat 9/196:00 am -
1 stop5h 46m
Deal found 8/30![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:24 am -
2 stops6h 57m
Sat 9/196:25 am -
1 stop5h 11m
Deal found 8/30![United Airlines logo]()
$354
Best flights from Des Moines to ColumbiaDiscover carefully curated flight deals from Des Moines to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
Discover carefully curated flight deals from Des Moines to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:13 pm -
1 stop7h 46m
Mon 10/55:18 pm -
1 stop6h 49m
Deal found 8/27![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:35 am -
1 stop6h 39m
Sun 10/1810:10 am -
1 stop4h 59m
Deal found 8/31![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:24 am -
2 stops11h 43m
Wed 9/166:25 am -
1 stop5h 06m
Deal found 8/28![United Airlines logo]()
$327
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:34 pm -
1 stop5h 34m
Wed 9/164:10 pm -
1 stop4h 38m
Deal found 8/28![American Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:24 am -
2 stops6h 57m
Sat 9/196:25 am -
1 stop5h 11m
Deal found 8/30![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:13 pm -
2 stops7h 52m
Sat 10/36:25 am -
1 stop6h 39m
Deal found 8/31![American Airlines logo]()
$353
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:27 am -
1 stop4h 30m
Tue 10/275:37 pm -
1 stop5h 18m
Deal found 8/31![United Airlines logo]()
$375
Last-minute flights from Des Moines to ColumbiaDiscover last-minute flight deals from Des Moines to Columbia. Data last updated September 1, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Columbia. Data last updated September 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:34 pm -
1 stop5h 34m
Wed 9/164:10 pm -
1 stop4h 38m
Deal found 8/28![American Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:24 am -
2 stops11h 43m
Wed 9/166:25 am -
1 stop5h 06m
Deal found 8/28![United Airlines logo]()
$327
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:45 am -
1 stop4h 27m
Sat 9/196:00 am -
1 stop5h 46m
Deal found 8/30![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:24 am -
2 stops6h 57m
Sat 9/196:25 am -
1 stop5h 11m
Deal found 8/30![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:13 pm -
1 stop7h 46m
Mon 10/55:18 pm -
1 stop6h 49m
Deal found 8/27![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:57 pm -
1 stop5h 06m
Sun 10/48:28 pm -
1 stop4h 24m
Deal found 8/27![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:56 pm -
1 stop5h 07m
Sat 10/38:18 am -
1 stop4h 46m
Deal found 8/31![American Airlines logo]()
$307
One-way flights from Des Moines to ColumbiaSearch for one-way flight options from Des Moines to Columbia. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
Search for one-way flight options from Des Moines to Columbia. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:34 pm -
1 stop5h 37m
Deal found 8/27![Delta logo]()
$274
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:45 am -
2 stops10h 12m
Deal found 8/28![United Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:00 am -
1 stop6h 03m
Deal found 8/30![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/135:45 am -
2 stops10h 18m
Deal found 8/30![United Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:22 pm -
2 stops15h 25m
Deal found 8/27![United Airlines logo]()
$438
Find flight deals from Des Moines to Columbia
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Columbia (CAE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $295 (Delta) |
One-way from | $274 (Delta) |
Popular in | July |
Cheapest in | January |
Average price | $385 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
Use the filters below to find and compare flights from Des Moines to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Fri 9/25
2:13 pm-10:59 pm
1 stop7h 46m
Columbia Metropolitan
Mon 10/5
5:18 pm-11:07 pm
1 stop6h 49m
$319
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Thu 10/15
5:35 am-1:14 pm
1 stop6h 39m
Columbia Metropolitan
Sun 10/18
10:10 am-2:09 pm
1 stop4h 59m
$319
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Sat 9/12
12:34 pm-7:08 pm
1 stop5h 34m
Columbia Metropolitan
Wed 9/16
4:10 pm-7:48 pm
1 stop4h 38m
$322
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Sat 9/12
6:24 am-7:07 pm
2 stops11h 43m
Columbia Metropolitan
Wed 9/16
6:25 am-10:31 am
1 stop5h 06m
$327
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Tue 9/29
2:13 pm-11:05 pm
2 stops7h 52m
Columbia Metropolitan
Sat 10/3
6:25 am-12:04 pm
1 stop6h 39m
$353
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Tue 9/15
6:24 am-2:21 pm
2 stops6h 57m
Columbia Metropolitan
Sat 9/19
6:25 am-10:36 am
1 stop5h 11m
$354
Quickest round-trip
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Sat 10/24
11:27 am-4:57 pm
1 stop4h 30m
Columbia Metropolitan
Tue 10/27
5:37 pm-9:55 pm
1 stop5h 18m
$375
Cheapest one-way
Quickest one-way
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Sat 9/26
5:45 am-11:12 am
1 stop4h 27m
$274
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Fri 9/25
2:34 pm-9:11 pm
1 stop5h 37m
$274
Des MoinesColumbia
DSM Des Moines - CAE Columbia Metropolitan
DSMCAE
Des Moines
Sat 9/26
5:45 am-4:57 pm
2 stops10h 12m
$279
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Columbia
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Columbia in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Columbia flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Columbia flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Columbia flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Columbia flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Columbia flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from Des Moines with our price prediction graph.
DSM-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Columbia
Reviews of airlines servicing Columbia
Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated September 1, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Des Moines to Columbia. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsIrmo
West Columbia
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Other flights to Columbia
Explore flights to Columbia departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 1, 2026.
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Des Moines and Columbia flights
Browse other Des Moines and Columbia flight options. Last updated on September 1, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Des Moines to Columbia
Discover the top 3 airlines that operate flights from Des Moines to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$476 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$274 | Average$357 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$299 | Average$391 | FlexibilityNo cancel fee | On-time71% |