$274+ Cheap flights from Des Moines to Columbia (DSM - CAE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CAE
Sep 3 — Sep 101
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Columbia with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Columbia
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Best
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One-way
Cheapest flights from Des Moines to ColumbiaExplore the most affordable flight options available from Des Moines to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 4, 2026.
Explore the most affordable flight options available from Des Moines to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 4, 2026.
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:56 pm -
1 stop5h 07m
Fri 9/116:47 pm -
1 stop5h 54m
Deal found 7/31![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:56 pm -
1 stop5h 07m
Wed 9/236:47 pm -
1 stop5h 54m
Deal found 8/1![American Airlines logo]()
$297
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:00 am -
2 stops7h 21m
Tue 9/86:25 am -
1 stop5h 06m
Deal found 8/3![United Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:34 pm -
1 stop5h 34m
Mon 9/146:47 pm -
1 stop5h 54m
Deal found 7/30![American Airlines logo]()
$317
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:56 pm -
1 stop5h 07m
Thu 9/246:47 pm -
1 stop5h 54m
Deal found 8/3![American Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:26 am -
1 stop5h 09m
Tue 9/86:46 pm -
1 stop5h 58m
Deal found 8/3![American Airlines logo]()
$332
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:00 am -
1 stop4h 40m
Sat 9/1910:22 am -
2 stops8h 06m
Deal found 8/2![United Airlines logo]()
$337
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:40 am -
1 stop4h 29m
Tue 9/811:57 am -
1 stop4h 18m
Deal found 8/3![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:13 pm -
1 stop7h 46m
Mon 10/55:18 pm -
1 stop6h 49m
Deal found 8/1![American Airlines logo]()
$391
Best flights from Des Moines to ColumbiaDiscover carefully curated flight deals from Des Moines to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 4, 2026.
Discover carefully curated flight deals from Des Moines to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 4, 2026.
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:56 pm -
1 stop5h 07m
Fri 9/116:47 pm -
1 stop5h 54m
Deal found 7/31![American Airlines logo]()
$295
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:24 am -
1 stop6h 16m
Mon 9/1410:22 am -
2 stops12h 06m
Deal found 7/30![United Airlines logo]()
$312
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:40 am -
1 stop6h 34m
Tue 9/87:30 am -
1 stop4h 16m
Deal found 8/3![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:56 pm -
1 stop5h 07m
Thu 9/246:47 pm -
1 stop5h 54m
Deal found 8/3![American Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:40 am -
1 stop4h 29m
Tue 9/811:57 am -
1 stop4h 18m
Deal found 8/3![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/63:15 pm -
2 stops7h 27m
Sat 1/95:25 pm -
1 stop4h 52m
Deal found 8/1![United Airlines logo]()
$380
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/293:15 pm -
1 stop5h 01m
Sat 2/135:25 pm -
1 stop6h 36m
Deal found 8/3![United Airlines logo]()
$387
Last-minute flights from Des Moines to ColumbiaDiscover last-minute flight deals from Des Moines to Columbia. Data last updated August 4, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Columbia. Data last updated August 4, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:40 am -
1 stop4h 29m
Tue 9/811:57 am -
1 stop4h 18m
Deal found 8/3![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:00 am -
2 stops7h 21m
Tue 9/86:25 am -
1 stop5h 06m
Deal found 8/3![United Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:26 am -
1 stop5h 09m
Tue 9/86:46 pm -
1 stop5h 58m
Deal found 8/3![American Airlines logo]()
$332
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:00 am -
2 stops7h 21m
Tue 9/86:25 am -
1 stop5h 06m
Deal found 8/3![United Airlines logo]()
$392
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:56 pm -
1 stop5h 07m
Fri 9/116:47 pm -
1 stop5h 54m
Deal found 7/31![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:34 pm -
1 stop5h 34m
Mon 9/146:47 pm -
1 stop5h 54m
Deal found 7/30![American Airlines logo]()
$317
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:00 am -
1 stop4h 40m
Sat 9/1910:22 am -
2 stops8h 06m
Deal found 8/2![United Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:56 pm -
1 stop5h 07m
Wed 9/236:47 pm -
1 stop5h 54m
Deal found 8/1![American Airlines logo]()
$297
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:56 pm -
1 stop5h 07m
Thu 9/246:47 pm -
1 stop5h 54m
Deal found 8/3![American Airlines logo]()
$321
One-way flights from Des Moines to ColumbiaSearch for one-way flight options from Des Moines to Columbia. Find affordable one-way fares based on user searches. Data last updated August 4, 2026.
Search for one-way flight options from Des Moines to Columbia. Find affordable one-way fares based on user searches. Data last updated August 4, 2026.
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:00 am -
1 stop4h 40m
Deal found 7/31![United Airlines logo]()
$274
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:20 pm -
1 stop5h 08m
Deal found 8/3![United Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:11 am -
1 stop6h 31m
Deal found 8/3![American Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am -
2 stops12h 09m
Deal found 8/3![United Airlines logo]()
$532
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:10 am -
1 stop4h 09m
Deal found 8/3![American Airlines logo]()
$574
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:20 pm -
3 stops26h 47m
Deal found 8/3![United Airlines logo]()
$743
Find flight deals from Des Moines to Columbia
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Columbia (CAE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $295 (American Airlines) |
One-way from | $274 (United Airlines) |
Popular in | August |
Cheapest in | January |
Average price | $831 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from Des Moines to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesColumbia
DSM - CAE
DSMCAE
Des Moines
Wed 9/9
5:56 pm-12:03 am
1 stop5h 07m
Columbia Metropolitan
Fri 9/11
6:47 pm-11:41 pm
1 stop5h 54m
$295
Des MoinesColumbia
DSM - CAE
DSMCAE
Des Moines
Sat 9/12
6:24 am-1:40 pm
1 stop6h 16m
Columbia Metropolitan
Mon 9/14
10:22 am-9:28 pm
2 stops12h 06m
$312
Des MoinesColumbia
DSM - CAE
DSMCAE
Des Moines
Thu 9/17
5:56 pm-12:03 am
1 stop5h 07m
Columbia Metropolitan
Thu 9/24
6:47 pm-11:41 pm
1 stop5h 54m
$321
Des MoinesColumbia
DSM - CAE
DSMCAE
Des Moines
Wed 8/26
5:40 am-1:14 pm
1 stop6h 34m
Columbia Metropolitan
Tue 9/8
7:30 am-10:46 am
1 stop4h 16m
$359
Quickest round-trip
Des MoinesColumbia
DSM - CAE
DSMCAE
Des Moines
Mon 8/24
5:40 am-11:09 am
1 stop4h 29m
Columbia Metropolitan
Tue 9/8
11:57 am-3:15 pm
1 stop4h 18m
$359
Des MoinesColumbia
DSM - CAE
DSMCAE
Des Moines
Wed 1/6
3:15 pm-11:42 pm
2 stops7h 27m
Columbia Metropolitan
Sat 1/9
5:25 pm-9:17 pm
1 stop4h 52m
$380
Des MoinesColumbia
DSM - CAE
DSMCAE
Des Moines
Fri 1/29
3:15 pm-9:16 pm
1 stop5h 01m
Columbia Metropolitan
Sat 2/13
5:25 pm-11:01 pm
1 stop6h 36m
$387
Cheapest one-way
Des MoinesColumbia
DSM - CAE
DSMCAE
Des Moines
Wed 9/23
8:00 am-1:40 pm
1 stop4h 40m
$274
Des MoinesColumbia
DSM - CAE
DSMCAE
Des Moines
Wed 8/12
6:33 am-1:34 pm
1 stop6h 01m
$387
Quickest one-way
Des MoinesColumbia
DSM - CAE
DSMCAE
Des Moines
Sun 8/9
7:10 am-12:19 pm
1 stop4h 09m
$574
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Columbia
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Columbia in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Columbia flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Columbia flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Columbia flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Columbia flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Columbia flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from Des Moines with our price prediction graph.
DSM-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Columbia
Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated August 4, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Des Moines to Columbia. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.8
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.8
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.8
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsIrmo
West Columbia
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Des Moines and Columbia flights
Browse other Des Moines and Columbia flight options. Last updated on August 4, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on August 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Columbia
Discover the top 2 airlines that operate flights from Des Moines to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$476 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$296 | Average$321 | FlexibilityNo cancel fee | On-time71% |