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$143+ Cheap flights from Des Moines to Columbia (DSM - CAE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CAE
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Des Moines to Columbia

Cheapest flights from Des Moines to Columbia
Explore the most affordable flight options available from Des Moines to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This American Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1712:57 pmDSM - CAE
1 stop4h 45mAmerican Airlines
Sun 12/217:59 pmCAE - DSM
1 stop5h 38mAmerican Airlines
Deal found 12/1$309
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:34 amDSM - CAE
1 stop5h 33mDelta
Mon 12/2210:56 amCAE - DSM
1 stop7h 19mDelta
Deal found 12/3$383
This American Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/201:56 pmDSM - CAE
1 stop7h 02mAmerican Airlines
Mon 1/197:10 pmCAE - DSM
1 stop4h 58mAmerican Airlines
Deal found 12/1$391
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1812:56 pmDSM - CAE
1 stop7h 51mAmerican Airlines
Mon 12/229:05 amCAE - DSM
2 stops7h 19mAmerican Airlines
Deal found 12/3$412
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/201:56 pmDSM - CAE
1 stop4h 37mAmerican Airlines
Sun 1/47:59 pmCAE - DSM
1 stop5h 38mAmerican Airlines
Deal found 12/2$436
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/201:56 pmDSM - CAE
1 stop4h 37mAmerican Airlines
Sat 1/35:07 amCAE - DSM
2 stops8h 47mAmerican Airlines
Deal found 12/2$489
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:46 pmDSM - CAE
1 stop4h 40mUnited Airlines
Mon 12/226:20 amCAE - DSM
1 stop12h 45mUnited Airlines
Deal found 12/3$498

Find flight deals from Des Moines to Columbia

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Columbia (CAE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

One-way from

$143
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$423
Provider with most accurate pricing for Des Moines-Columbia Metropolitan flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Columbia Metropolitan flights.
Search Deals
From Des Moines to Columbia Metropolitan
Search Deals
One-way flight from Des Moines to Columbia Metropolitan
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Des Moines to Columbia that are best for you.

Fly from

Des Moines

Fly to

Columbia

Route

Depart

Return

Price

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sat 2/14

1:02 pm-8:27 pm

1 stop6h 25m

Columbia Metropolitan

Wed 2/18

6:40 am-10:40 am

1 stop5h 00m

$249

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Thu 2/12

7:01 am-4:59 pm

1 stop8h 58m

Columbia Metropolitan

Sun 2/15

7:22 am-1:09 pm

1 stop6h 47m

$274

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Wed 12/17

12:57 pm-6:42 pm

1 stop4h 45m

Columbia Metropolitan

Sun 12/21

7:59 pm-12:37 am

1 stop5h 38m

$309

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sun 1/18

3:35 pm-9:21 pm

1 stop4h 46m

Columbia Metropolitan

Sun 1/25

5:07 pm-9:50 pm

1 stop5h 43m

$319

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sat 1/17

3:35 pm-9:21 pm

1 stop4h 46m

Columbia Metropolitan

Sat 1/24

10:10 am-8:34 pm

2 stops11h 24m

$324

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sat 2/14

12:19 pm-10:00 pm

2 stops8h 41m

Columbia Metropolitan

Wed 2/18

6:00 am-1:09 pm

1 stop8h 09m

$324

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Thu 12/18

5:34 am-12:07 pm

1 stop5h 33m

Columbia Metropolitan

Mon 12/22

10:56 am-5:15 pm

1 stop7h 19m

$383

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sat 12/13

10:38 am-3:17 pm

1 stop27h 39m

$143

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sat 12/27

6:46 pm-12:26 am

1 stop4h 40m

$239

Des MoinesColumbia

DSM - CAE

DSMCAE

Des Moines

Sat 1/17

5:30 am-6:55 pm

2 stops12h 25m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 16 results
1
2

Compare providers for flights from Des Moines to Columbia

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Columbia in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Columbia flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Columbia flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Columbia flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Columbia flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Columbia flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Columbia

Have a flexible travel schedule? Discover the best time to fly to Columbia from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Columbia

What is the cheapest month to book a flight from Des Moines to Columbia?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Columbia (average of $166). Flying from Des Moines to Columbia in November is currently the most expensive (average of $288). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Columbia

Get insights into the airlines that provide service to Columbia. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbia. Reviews last updated December 4, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Des Moines to Columbia. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.9

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Columbia?

    A quick flight from Des Moines to Columbia can take about 4h 46m. Delta provides one of the quickest options available for as low as $319. There are 861 mi between Des Moines and Columbia. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Columbia round-trip?

    Currently priced at $248, American Airlines will fly you from Des Moines to Columbia and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $248. American Airlines is 32% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Des Moines to Columbia that include hotel bookings?

    Yes. In addition to deals on Des Moines to Columbia flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Columbia?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Columbia.

  • Can I find deals for business class flights from Des Moines to Columbia?

    Yes. Cheapflights offers flight deals from Des Moines to Columbia by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Columbia?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Columbia (average of $166). Flying from Des Moines to Columbia in November is currently the most expensive (average of $288). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Columbia?

Book flights to Columbia if you plan to visit one of these locations
West Columbia

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Top 2 airlines flying from Des Moines to Columbia

Discover the top 2 airlines that operate flights from Des Moines to Columbia. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$363FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$363FlexibilityNo cancel feeOn-timeN/A

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