$159+ Cheap flights from Chicago (CHI) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — BOG
Sep 15 — Sep 221
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Chicago to South America
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Cheapest flights from Chicago to South AmericaExplore the most affordable flight options available from Chicago to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2026.
Explore the most affordable flight options available from Chicago to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:20 pm -
1 stop19h 40m
Wed 9/309:45 am -
1 stop15h 17m
Deal found 8/15![Copa Airlines logo]()
$341
This Copa Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:13 pm -
1 stop26h 42m
Mon 12/149:35 am -
1 stop15h 36m
Deal found 8/12![Copa Airlines logo]()
$365
This Copa Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:20 pm -
1 stop16h 45m
Sun 9/276:20 am -
1 stop18h 42m
Deal found 8/12![Copa Airlines logo]()
$369
This Copa Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:20 pm -
1 stop16h 45m
Mon 9/286:20 am -
1 stop18h 42m
Deal found 8/14![Copa Airlines logo]()
$373
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop8h 36m
Sat 11/142:35 pm -
1 stop11h 09m
Deal found 8/13![American Airlines logo]()
$377
This Despegar deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Despegar is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:30 am -
1 stop7h 45m
Sat 10/32:30 pm -
1 stop9h 29m
Deal found 8/12![LATAM Airlines logo]()
$378
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:59 pm -
1 stop17h 36m
Sat 9/53:15 pm -
1 stop8h 15m
Deal found 8/11![American Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:10 pm -
2 stops19h 55m
Sat 9/192:30 pm -
1 stop9h 29m
Deal found 8/14![Delta logo]()
$382
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:40 pm -
1 stop21h 25m
Thu 9/242:30 pm -
1 stop9h 29m
Deal found 8/13![Delta logo]()
$385
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:30 am -
1 stop7h 35m
Sat 9/52:30 pm -
2 stops20h 12m
Deal found 8/11![Delta logo]()
$386
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:20 pm -
1 stop16h 45m
Sun 10/116:20 am -
1 stop18h 37m
Deal found 8/15![Copa Airlines logo]()
$387
This FlightHub deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:30 am -
1 stop13h 45m
Tue 10/62:55 pm -
1 stop18h 30m
Deal found 8/11![LATAM Airlines logo]()
$411
Best flights from Chicago to South AmericaDiscover carefully curated flight deals from Chicago to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 16, 2026.
Discover carefully curated flight deals from Chicago to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 16, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:13 pm -
1 stop26h 42m
Mon 12/149:35 am -
1 stop14h 28m
Deal found 8/16![Copa Airlines logo]()
$365
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1210:40 am -
1 stop8h 40m
Fri 9/258:30 am -
1 stop13h 12m
Deal found 8/12![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:27 am -
1 stop13h 48m
Mon 10/122:55 pm -
1 stop18h 30m
Deal found 8/15![Delta logo]()
$425
This Copa Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:20 pm -
1 stop26h 35m
Sun 11/19:35 am -
1 stop15h 36m
Deal found 8/11![Copa Airlines logo]()
$369
This Expedia deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:30 am -
1 stop26h 45m
Sun 10/181:35 am -
1 stop21h 45m
Deal found 8/15![Multiple Airlines logo]()
$762
This Copa Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:20 pm -
1 stop26h 35m
Sun 10/116:20 am -
1 stop18h 37m
Deal found 8/12![Copa Airlines logo]()
$373
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:28 pm -
1 stop10h 26m
Tue 9/228:30 am -
1 stop13h 02m
Deal found 8/15![United Airlines logo]()
$425
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:10 am -
2 stops14h 00m
Tue 9/292:55 pm -
2 stops17h 01m
Deal found 8/11![Delta logo]()
$430
This Copa Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:02 am -
1 stop24h 03m
Thu 9/39:45 am -
1 stop15h 17m
Deal found 8/15![Copa Airlines logo]()
$373
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:10 pm -
2 stops20h 30m
Tue 9/2211:00 am -
2 stops12h 59m
Deal found 8/13![Delta logo]()
$430
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:25 am -
1 stop14h 45m
Sun 10/259:45 am -
1 stop15h 00m
Deal found 8/11![United Airlines logo]()
$447
This Copa Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:20 pm -
1 stop16h 45m
Sun 10/116:20 am -
1 stop18h 37m
Deal found 8/12![Copa Airlines logo]()
$373
This Arajet deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:45 am -
1 stop22h 00m
Sun 9/208:40 am -
1 stop15h 30m
Deal found 8/15![Arajet logo]()
$1,008
This GOL deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:10 pm -
2 stops36h 45m
Tue 8/259:55 pm -
2 stops28h 40m
Deal found 8/11![GOL logo]()
$1,016
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:30 am -
2 stops12h 40m
Wed 11/1810:45 am -
2 stops14h 14m
Deal found 8/14![Delta logo]()
$430
This Air Canada deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:05 am -
2 stops20h 00m
Mon 11/29:45 pm -
2 stops20h 53m
Deal found 8/15![Air Canada logo]()
$1,071
This Copa Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/193:20 pm -
1 stop17h 20m
Sun 9/276:20 am -
1 stop18h 42m
Deal found 8/13![Copa Airlines logo]()
$373
This LATAM Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:04 am -
2 stops15h 26m
Tue 10/1310:15 pm -
2 stops24h 18m
Deal found 8/13![LATAM Airlines logo]()
$1,134
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:30 am -
1 stop16h 00m
Wed 11/181:35 am -
1 stop11h 54m
Deal found 8/15![United Airlines logo]()
$508
This Copa Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:13 pm -
1 stop26h 13m
Wed 11/1812:08 pm -
1 stop13h 03m
Deal found 8/11![Copa Airlines logo]()
$413
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:40 am -
1 stop12h 19m
Fri 10/212:59 am -
2 stops11h 59m
Deal found 8/12![Delta logo]()
$512
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:30 am -
2 stops17h 30m
Mon 10/123:05 pm -
2 stops30h 27m
Deal found 8/11![United Airlines logo]()
$530
This Copa Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:13 pm -
1 stop18h 57m
Sun 11/1512:08 pm -
1 stop13h 03m
Deal found 8/11![Copa Airlines logo]()
$413
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:30 am -
1 stop13h 29m
Fri 10/29:00 am -
2 stops14h 59m
Deal found 8/11![Delta logo]()
$512
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:35 pm -
2 stops25h 25m
Sat 9/129:45 am -
2 stops23h 24m
Deal found 8/14![United Airlines logo]()
$530
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:30 am -
1 stop14h 55m
Mon 11/210:30 am -
2 stops36h 50m
Deal found 8/15![Multiple Airlines logo]()
$777
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:19 pm -
2 stops23h 33m
Thu 11/2612:55 am -
1 stop19h 07m
Deal found 8/12![Delta logo]()
$512
This Copa Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:01 am -
1 stop24h 14m
Fri 10/235:00 am -
1 stop19h 57m
Deal found 8/14![Copa Airlines logo]()
$435
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:27 am -
2 stops13h 38m
Thu 10/2911:45 pm -
2 stops16h 47m
Deal found 8/11![Delta logo]()
$512
This Copa Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/143:20 pm -
1 stop19h 35m
Mon 9/214:30 pm -
1 stop8h 32m
Deal found 8/14![Copa Airlines logo]()
$435
Last-minute flights from Chicago to South AmericaDiscover last-minute flight deals from Chicago to South America. Data last updated August 16, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to South America. Data last updated August 16, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:59 pm -
1 stop17h 36m
Sat 9/53:15 pm -
1 stop8h 15m
Deal found 8/11![American Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:30 am -
1 stop7h 35m
Sat 9/52:30 pm -
2 stops20h 12m
Deal found 8/11![Delta logo]()
$386
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:10 pm -
2 stops19h 55m
Sat 9/192:30 pm -
1 stop9h 29m
Deal found 8/14![Delta logo]()
$382
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:40 pm -
1 stop21h 25m
Thu 9/242:30 pm -
1 stop9h 29m
Deal found 8/13![Delta logo]()
$385
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:30 am -
1 stop7h 35m
Sat 9/192:30 pm -
1 stop9h 29m
Deal found 8/15![Delta logo]()
$377
This Copa Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/163:20 pm -
1 stop16h 45m
Wed 9/236:20 am -
1 stop18h 42m
Deal found 8/13![Copa Airlines logo]()
$365
This FlightHub deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:30 am -
1 stop13h 45m
Tue 10/62:55 pm -
1 stop18h 30m
Deal found 8/11![LATAM Airlines logo]()
$411
This Copa Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:20 pm -
1 stop16h 45m
Sun 9/276:20 am -
1 stop18h 42m
Deal found 8/12![Copa Airlines logo]()
$369
This Copa Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:20 pm -
1 stop16h 45m
Mon 9/286:20 am -
1 stop18h 42m
Deal found 8/14![Copa Airlines logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:20 pm -
1 stop19h 40m
Wed 9/309:45 am -
1 stop15h 17m
Deal found 8/15![Copa Airlines logo]()
$341
This Despegar deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Despegar is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:30 am -
1 stop7h 45m
Sat 10/32:30 pm -
1 stop9h 29m
Deal found 8/12![LATAM Airlines logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:20 pm -
1 stop16h 45m
Sun 10/116:20 am -
1 stop18h 37m
Deal found 8/15![Copa Airlines logo]()
$387
One-way flights from Chicago to South AmericaSearch for one-way flight options from Chicago to South America. Find affordable one-way fares based on user searches. Data last updated August 16, 2026.
Search for one-way flight options from Chicago to South America. Find affordable one-way fares based on user searches. Data last updated August 16, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:20 pm -
1 stop16h 45m
Deal found 8/14![Copa Airlines logo]()
$159
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:00 am -
1 stop7h 35m
Deal found 8/11![American Airlines logo]()
$162
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:55 pm -
2 stops15h 40m
Deal found 8/14![American Airlines logo]()
$168
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:53 pm -
2 stops15h 42m
Deal found 8/14![American Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:20 am -
2 stops25h 55m
Deal found 8/14![Multiple Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:20 am -
2 stops25h 55m
Deal found 8/15![Multiple Airlines logo]()
$177
This Copa Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:13 pm -
1 stop17h 22m
Deal found 8/12![Copa Airlines logo]()
$178
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:20 pm -
2 stops19h 45m
Deal found 8/15![Delta logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:20 am -
2 stops25h 55m
Deal found 8/15![Multiple Airlines logo]()
$181
This FlightHub deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:30 am -
1 stop8h 10m
Deal found 8/12![LATAM Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:20 pm -
1 stop19h 35m
Deal found 8/13![Copa Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:45 am -
1 stop9h 00m
Deal found 8/11![Arajet logo]()
$183
Find flight deals from Chicago to South America
Keep the following information in mind while searching for Chicago to South America flight deals. Data was last updated August 16, 2026.
Round-trip from | $341 (Kiwi.com) |
|---|---|
One-way from | $159 (Copa Airlines) |
Popular in | December |
Cheapest in | February |
Average price | $445 |
Good round-trip deal | $508 or less |
Good one-way deal | $426 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2026.
Use the filters below to find and compare flights from Chicago to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Wed 12/2
2:13 pm-5:55 pm
1 stop26h 42m
Cartagena Rafael Nunez
Mon 12/14
9:35 am-11:03 pm
1 stop14h 28m
$365
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Sat 10/24
3:20 pm-5:55 pm
1 stop26h 35m
Cartagena Rafael Nunez
Sun 11/1
9:35 am-12:11 am
1 stop15h 36m
$369
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Wed 9/30
3:20 pm-5:55 pm
1 stop26h 35m
Cartagena Rafael Nunez
Sun 10/11
6:20 am-12:57 am
1 stop18h 37m
$373
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Wed 8/26
8:02 am-8:05 am
1 stop24h 03m
Cartagena Rafael Nunez
Thu 9/3
9:45 am-1:02 am
1 stop15h 17m
$373
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Wed 10/7
3:20 pm-8:05 am
1 stop16h 45m
Cartagena Rafael Nunez
Sun 10/11
6:20 am-12:57 am
1 stop18h 37m
$373
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Sat 9/19
3:20 pm-8:40 am
1 stop17h 20m
Cartagena Rafael Nunez
Sun 9/27
6:20 am-1:02 am
1 stop18h 42m
$373
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Fri 11/6
2:13 pm-5:26 pm
1 stop26h 13m
Bogotá El Dorado
Wed 11/18
12:08 pm-12:11 am
1 stop13h 03m
$413
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Mon 11/9
2:13 pm-10:10 am
1 stop18h 57m
Bogotá El Dorado
Sun 11/15
12:08 pm-12:11 am
1 stop13h 03m
$413
Quickest round-trip
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Sat 9/12
10:40 am-7:20 pm
1 stop8h 40m
Bogotá El Dorado
Fri 9/25
8:30 am-9:42 pm
1 stop13h 12m
$414
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Thu 10/8
5:27 am-7:15 pm
1 stop13h 48m
Bogotá El Dorado
Mon 10/12
2:55 pm-9:25 am
1 stop18h 30m
$425
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Chicago to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Chicago with our price prediction graph.
ORD-CTG
ORD-BOG
ORD-GIG
ORD-MDE
ORD-EZE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to South America
CHI-0SA
ORD-CTG
ORD-BOG
ORD-GIG
ORD-MDE
What is the cheapest month to book a flight from Chicago to South America?
Currently, February is the cheapest month in which you can book a flight from Chicago to South America (average of $533). Flying from Chicago to South America in December is currently the most expensive (average of $840). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to SA?
Find hourly flight availability from Chicago to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 16, 2026.
When flying from Chicago to South America, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 44% versus a flight in the afternoon.
Weekly flight availability from Chicago to South America
Explore weekly flight availability from Chicago to South America. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 16, 2026.
The most flights from CHI to 0SA are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).
How far ahead should I book a flight from Chicago to South America?
The price you pay for your flight from Chicago to South America may vary depending on when you book. For the best chance of a lower fare, look to book 34 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated August 16, 2026.
Read reviews from past customers who have flown Copa Airlines,LATAM Airlines, andUnited Airlines from Chicago to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Entertainment
6.8
Overall
7.6
Food
6.9
Boarding
7.8
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Entertainment
6.8
Overall
7.6
Food
6.9
Boarding
7.8
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Entertainment
6.8
Overall
7.6
Food
6.9
Boarding
7.8
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Entertainment
6.8
Overall
7.6
Food
6.9
Boarding
7.8
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Entertainment
6.8
Overall
7.6
Food
6.9
Boarding
7.8
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Entertainment
6.8
Overall
7.6
Food
6.9
Boarding
7.8
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Chicago to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to South America by cabin class
Find flights from Chicago to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and South America flights
Browse other Chicago and South America flight options. Last updated on August 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Chicago to South America flights
Consider these flights traveling from Chicago to South America.
Top 10 airlines flying from Chicago to South America
Discover the top 10 airlines that operate flights from Chicago to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$153 | Average$803 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$161 | Average$661 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$204 | Average$777 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$212 | Average$747 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$262 | Average$620 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$269 | Average$704 | FlexibilityNo cancel fee | On-time74% | |
| Cheapest$272 | Average$712 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$298 | Average$655 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$317 | Average$836 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$479 | Average$732 | FlexibilityNo cancel fee | On-time67% |