$158+ Cheap flights from Chicago (CHI) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — BOG
Oct 23 — Oct 301
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Chicago to South America
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Cheapest flights from Chicago to South AmericaExplore the most affordable flight options available from Chicago to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
Explore the most affordable flight options available from Chicago to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/142:13 pm -
1 stop17h 02m
Fri 11/209:35 am -
1 stop15h 36m
Deal found 9/18![Copa Airlines logo]()
$405
This Copa Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:13 pm -
1 stop22h 52m
Fri 11/203:05 pm -
1 stop10h 06m
Deal found 9/23![Copa Airlines logo]()
$406
This Avianca deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:30 pm -
1 stop12h 55m
Tue 11/177:10 am -
1 stop14h 20m
Deal found 9/19![Avianca logo]()
$414
This Avianca deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:30 pm -
1 stop12h 55m
Sat 11/1411:15 am -
1 stop10h 15m
Deal found 9/23![Avianca logo]()
$415
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:00 am -
1 stop9h 36m
Tue 11/102:35 pm -
1 stop10h 21m
Deal found 9/23![American Airlines logo]()
$416
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:50 pm -
1 stop16h 45m
Fri 11/204:34 pm -
1 stop17h 56m
Deal found 9/18![American Airlines logo]()
$417
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:27 am -
1 stop7h 48m
Thu 11/53:30 pm -
1 stop9h 27m
Deal found 9/21![Delta logo]()
$418
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:35 am -
1 stop9h 30m
Fri 11/63:05 pm -
1 stop10h 06m
Deal found 9/23![Copa Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop8h 36m
Fri 11/204:34 pm -
2 stops15h 56m
Deal found 9/18![American Airlines logo]()
$420
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:27 am -
1 stop7h 48m
Wed 11/113:34 pm -
2 stops17h 15m
Deal found 9/22![Delta logo]()
$423
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:35 am -
1 stop26h 32m
Mon 11/92:30 pm -
1 stop23h 16m
Deal found 9/21![Copa Airlines logo]()
$433
This Copa Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:13 pm -
1 stop9h 07m
Mon 11/96:08 pm -
1 stop19h 38m
Deal found 9/23![Copa Airlines logo]()
$434
Best flights from Chicago to South AmericaDiscover carefully curated flight deals from Chicago to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
Discover carefully curated flight deals from Chicago to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/142:13 pm -
1 stop22h 52m
Fri 11/2012:05 pm -
1 stop13h 06m
Deal found 9/19![Copa Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:27 am -
1 stop7h 48m
Thu 11/53:30 pm -
1 stop9h 27m
Deal found 9/22![Delta logo]()
$418
This Avianca deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:30 pm -
1 stop11h 05m
Sun 11/159:20 am -
1 stop12h 10m
Deal found 9/18![Avianca logo]()
$434
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:25 am -
1 stop16h 10m
Mon 11/98:15 am -
1 stop16h 11m
Deal found 9/18![United Airlines logo]()
$445
This GOL deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:31 pm -
1 stop18h 44m
Wed 11/411:55 pm -
1 stop21h 28m
Deal found 9/20![GOL logo]()
$551
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:13 pm -
1 stop17h 22m
Sun 11/226:25 am -
1 stop18h 46m
Deal found 9/22![Copa Airlines logo]()
$406
This FlightHub deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/151:30 pm -
1 stop14h 25m
Thu 4/156:40 am -
2 stops18h 10m
Deal found 9/18![LATAM Airlines logo]()
$857
This Arajet deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:20 am -
1 stop16h 45m
Wed 11/41:05 am -
1 stop24h 35m
Deal found 9/20![Arajet logo]()
$875
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:27 am -
1 stop7h 48m
Sat 11/73:30 pm -
1 stop9h 27m
Deal found 9/22![Delta logo]()
$438
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:34 am -
1 stop11h 01m
Sat 11/78:15 am -
1 stop11h 15m
Deal found 9/22![United Airlines logo]()
$446
This Avianca deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:30 pm -
1 stop10h 30m
Sun 11/1510:00 am -
1 stop11h 30m
Deal found 9/21![Avianca logo]()
$448
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:13 pm -
1 stop22h 52m
Mon 11/166:25 am -
1 stop18h 46m
Deal found 9/18![Copa Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:00 am -
1 stop18h 05m
Wed 11/118:15 am -
1 stop11h 15m
Deal found 9/23![United Airlines logo]()
$446
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:44 am -
1 stop8h 46m
Fri 11/66:35 pm -
2 stops25h 36m
Deal found 9/18![Delta logo]()
$465
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:13 pm -
1 stop22h 52m
Wed 11/183:05 pm -
1 stop22h 41m
Deal found 9/21![Copa Airlines logo]()
$425
This GOL deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/38:43 am -
1 stop18h 32m
Sun 3/76:55 am -
2 stops44h 43m
Deal found 9/22![GOL logo]()
$559
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:25 am -
1 stop14h 45m
Thu 11/1910:40 am -
1 stop13h 46m
Deal found 9/20![United Airlines logo]()
$467
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:13 pm -
1 stop18h 12m
Wed 11/188:40 am -
1 stop16h 31m
Deal found 9/19![Copa Airlines logo]()
$433
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:10 am -
2 stops12h 55m
Sun 11/812:55 am -
1 stop19h 10m
Deal found 9/18![Delta logo]()
$512
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2310:30 am -
1 stop10h 40m
Fri 1/2910:40 am -
1 stop13h 19m
Deal found 9/22![United Airlines logo]()
$468
This Copa Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:13 pm -
1 stop25h 50m
Mon 11/3010:40 am -
1 stop14h 31m
Deal found 9/18![Copa Airlines logo]()
$433
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:30 pm -
2 stops23h 29m
Tue 11/2412:55 am -
1 stop19h 10m
Deal found 9/20![Delta logo]()
$512
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:45 pm -
1 stop23h 20m
Fri 11/2010:40 am -
1 stop13h 46m
Deal found 9/20![United Airlines logo]()
$476
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/12:13 pm -
1 stop8h 52m
Sun 11/84:45 am -
1 stop20h 26m
Deal found 9/20![Copa Airlines logo]()
$433
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:20 am -
2 stops12h 45m
Fri 11/612:55 am -
1 stop17h 03m
Deal found 9/18![Delta logo]()
$512
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:13 pm -
1 stop26h 13m
Mon 11/307:00 am -
1 stop18h 11m
Deal found 9/22![Copa Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:55 am -
1 stop16h 35m
Tue 12/227:45 am -
1 stop16h 39m
Deal found 9/18![United Airlines logo]()
$508
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:49 am -
2 stops11h 03m
Mon 11/2312:55 am -
2 stops14h 04m
Deal found 9/20![Delta logo]()
$512
This Avianca deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/1410:30 pm -
2 stops35h 40m
Fri 4/164:40 pm -
1 stop30h 40m
Deal found 9/22![Avianca logo]()
$767
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/152:13 pm -
1 stop18h 57m
Sun 11/226:10 am -
1 stop19h 01m
Deal found 9/22![Copa Airlines logo]()
$434
Last-minute flights from Chicago to South AmericaDiscover last-minute flight deals from Chicago to South America. Data last updated September 23, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to South America. Data last updated September 23, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:20 pm -
1 stop22h 45m
Wed 10/2812:05 pm -
1 stop13h 00m
Deal found 9/19![Copa Airlines logo]()
$424
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:20 pm -
1 stop19h 46m
Sun 11/87:00 am -
1 stop18h 11m
Deal found 9/20![Copa Airlines logo]()
$433
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:20 pm -
1 stop9h 02m
Wed 10/284:40 pm -
1 stop8h 25m
Deal found 9/21![Copa Airlines logo]()
$434
This Avianca deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:20 pm -
1 stop13h 05m
Wed 10/2810:40 am -
1 stop10h 50m
Deal found 9/19![Avianca logo]()
$414
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:58 pm -
2 stops15h 37m
Thu 10/291:35 pm -
2 stops17h 52m
Deal found 9/21![American Airlines logo]()
$421
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:13 pm -
1 stop7h 47m
Sun 11/13:05 pm -
1 stop10h 06m
Deal found 9/19![Copa Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:29 pm -
2 stops15h 06m
Tue 11/32:35 pm -
1 stop10h 21m
Deal found 9/20![American Airlines logo]()
$422
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:44 am -
1 stop26h 31m
Wed 11/113:34 pm -
1 stop18h 07m
Deal found 9/22![Delta logo]()
$426
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:44 am -
1 stop26h 31m
Thu 11/53:30 pm -
2 stops17h 11m
Deal found 9/22![Delta logo]()
$431
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:05 am -
1 stop7h 30m
Mon 11/24:37 pm -
1 stop9h 07m
Deal found 9/20![American Airlines logo]()
$417
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:27 am -
1 stop7h 48m
Thu 11/53:30 pm -
1 stop9h 27m
Deal found 9/22![Delta logo]()
$418
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:27 am -
1 stop7h 48m
Wed 11/113:34 pm -
2 stops17h 15m
Deal found 9/22![Delta logo]()
$423
One-way flights from Chicago to South AmericaSearch for one-way flight options from Chicago to South America. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
Search for one-way flight options from Chicago to South America. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
This FlightHub deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/145:24 pm -
1 stop17h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Frontier logo]()
$158
This Volaris deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1012:53 pm -
1 stop23h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Volaris logo]()
$171
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
1 stop8h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![American Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/195:45 am -
1 stop9h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Arajet logo]()
$187
This CheapOair deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:45 am -
1 stop8h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Arajet logo]()
$187
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
1 stop8h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![American Airlines logo]()
$190
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:00 am -
1 stop7h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![American Airlines logo]()
$192
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:30 am -
1 stop17h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![United Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:20 pm -
1 stop9h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Copa Airlines logo]()
$193
This Volaris deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/512:53 pm -
1 stop23h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Volaris logo]()
$194
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/12:13 pm -
1 stop8h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Copa Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:41 am -
2 stops21h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$196
Find flight deals from Chicago to South America
Keep the following information in mind while searching for Chicago to South America flight deals. Data was last updated September 23, 2026.
Round-trip from | $405 (Copa Airlines) |
|---|---|
One-way from | $158 (FlightHub) |
Popular in | December |
Cheapest in | February |
Average price | $467 |
Good round-trip deal | $531 or less |
Good one-way deal | $416 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
Use the filters below to find and compare flights from Chicago to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Mon 11/30
7:00 am-10:55 pm
2 stops14h 55m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$190
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Mon 11/9
7:29 am-10:35 pm
1 stop14h 06m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$192
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Wed 11/25
2:13 pm-5:03 pm
1 stop25h 50m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$195
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Mon 11/2
2:13 pm-11:07 am
1 stop19h 54m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$195
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Tue 11/24
2:13 pm-11:07 am
1 stop19h 54m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$195
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Tue 11/3
2:13 pm-9:25 am
1 stop18h 12m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$195
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Sun 10/25
3:13 pm-10:10 am
1 stop18h 57m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$195
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Thu 11/5
10:34 am-10:35 pm
1 stop11h 01m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$198
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Thu 10/29
5:30 am-10:35 pm
1 stop17h 05m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$198
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Thu 11/12
2:13 pm-2:05 pm
1 stop22h 52m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$198
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Chicago to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Chicago with our price prediction graph.
ORD-CTG
ORD-BOG
ORD-MDE
ORD-GIG
ORD-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to South America
CHI-0SA
ORD-CTG
ORD-BOG
ORD-MDE
ORD-GIG
What is the cheapest month to book a flight from Chicago to South America?
Currently, February is the cheapest month in which you can book a flight from Chicago to South America (average of $538). Flying from Chicago to South America in December is currently the most expensive (average of $829). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to SA?
Find hourly flight availability from Chicago to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 23, 2026.
When flying from Chicago to South America, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 44% versus a flight in the afternoon.
How far ahead should I book a flight from Chicago to South America?
The price you pay for your flight from Chicago to South America may vary depending on when you book. For the best chance of a lower fare, look to book 34 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 23, 2026.
Read reviews from past customers who have flown Copa Airlines,LATAM Airlines, andUnited Airlines from Chicago to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Overall
7.6
Comfort
7.4
Boarding
7.8
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Overall
7.6
Comfort
7.4
Boarding
7.8
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Overall
7.6
Comfort
7.4
Boarding
7.8
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Overall
7.6
Comfort
7.4
Boarding
7.8
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Overall
7.6
Comfort
7.4
Boarding
7.8
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Overall
7.6
Comfort
7.4
Boarding
7.8
Crew
8.1
Food
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Chicago to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to South America by cabin class
Find flights from Chicago to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and South America flights
Browse other Chicago and South America flight options. Last updated on September 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Chicago to South America flights
Consider these flights traveling from Chicago to South America.
Top 10 airlines flying from Chicago to South America
Discover the top 10 airlines that operate flights from Chicago to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$153 | Average$794 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$161 | Average$661 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$185 | Average$752 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$204 | Average$822 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$245 | Average$645 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$269 | Average$730 | FlexibilityNo cancel fee | On-time74% | |
| Cheapest$272 | Average$712 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$296 | Average$856 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$298 | Average$661 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$319 | Average$765 | FlexibilityNo cancel fee | On-time67% |