$168+ Cheap flights from Chicago (CHI) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — BOG
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Chicago to South America
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Cheapest flights from Chicago to South AmericaExplore the most affordable flight options available from Chicago to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Chicago to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/142:13 pm -
1 stop17h 02m
Fri 11/206:25 am -
1 stop18h 46m
Deal found 9/4![Copa Airlines logo]()
$365
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:30 am -
1 stop7h 45m
Thu 9/172:30 pm -
2 stops25h 43m
Deal found 9/6![Delta logo]()
$388
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:13 pm -
1 stop7h 47m
Sat 11/1412:05 pm -
1 stop13h 06m
Deal found 9/4![Copa Airlines logo]()
$393
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop8h 36m
Sat 11/142:35 pm -
1 stop11h 09m
Deal found 9/5![American Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
1 stop8h 36m
Thu 11/124:37 pm -
1 stop16h 23m
Deal found 9/7![American Airlines logo]()
$401
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:11 pm -
2 stops15h 24m
Fri 11/204:34 pm -
2 stops15h 56m
Deal found 9/5![American Airlines logo]()
$402
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:13 pm -
1 stop17h 22m
Mon 11/166:25 am -
1 stop18h 46m
Deal found 9/7![Copa Airlines logo]()
$404
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:20 pm -
1 stop22h 45m
Mon 10/266:25 am -
1 stop18h 40m
Deal found 9/5![Copa Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:15 pm -
1 stop20h 19m
Tue 11/242:35 pm -
1 stop18h 25m
Deal found 9/6![American Airlines logo]()
$407
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:10 pm -
2 stops19h 55m
Sat 9/192:30 pm -
1 stop9h 29m
Deal found 9/6![Delta logo]()
$410
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:20 pm -
1 stop25h 47m
Fri 10/304:40 pm -
1 stop8h 25m
Deal found 9/4![Copa Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/262:13 pm -
1 stop9h 07m
Wed 12/94:40 pm -
1 stop8h 31m
Deal found 9/7![Copa Airlines logo]()
$416
Best flights from Chicago to South AmericaDiscover carefully curated flight deals from Chicago to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Chicago to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/26:00 am -
1 stop7h 50m
Sun 3/74:00 pm -
1 stop18h 39m
Deal found 9/6![United Airlines logo]()
$397
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:13 pm -
1 stop17h 22m
Tue 11/1712:05 pm -
1 stop13h 06m
Deal found 9/8![Copa Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:30 am -
1 stop13h 45m
Sat 10/172:55 pm -
1 stop9h 02m
Deal found 9/5![Delta logo]()
$445
This Volaris deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/812:53 pm -
1 stop23h 02m
Mon 12/142:00 pm -
1 stop22h 13m
Deal found 9/7![Volaris logo]()
$529
This FlightHub deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:04 am -
2 stops15h 01m
Wed 11/1111:40 pm -
1 stop11h 44m
Deal found 9/3![LATAM Airlines logo]()
$687
This KAYAK deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/13:20 am -
1 stop16h 05m
Thu 11/511:25 am -
1 stop14h 15m
Deal found 9/4![Arajet logo]()
$741
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/105:30 am -
1 stop8h 20m
Sat 1/162:20 pm -
1 stop11h 23m
Deal found 9/8![United Airlines logo]()
$397
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:20 pm -
1 stop22h 45m
Mon 10/266:25 am -
1 stop18h 40m
Deal found 9/5![Copa Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:27 am -
1 stop13h 03m
Sat 11/710:45 am -
2 stops14h 12m
Deal found 9/6![Delta logo]()
$450
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:35 am -
1 stop15h 45m
Mon 11/96:10 am -
1 stop19h 01m
Deal found 9/4![Copa Airlines logo]()
$413
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:55 am -
1 stop16h 10m
Thu 12/31:30 am -
1 stop9h 40m
Deal found 9/7![United Airlines logo]()
$445
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
2 stops13h 10m
Tue 11/1710:45 am -
2 stops14h 09m
Deal found 9/5![Delta logo]()
$450
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:13 pm -
1 stop22h 52m
Sat 11/76:25 am -
1 stop18h 46m
Deal found 9/4![Copa Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:40 am -
1 stop12h 35m
Wed 9/302:55 pm -
1 stop17h 41m
Deal found 9/7![Delta logo]()
$458
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:53 pm -
1 stop11h 01m
Mon 9/218:30 am -
1 stop14h 57m
Deal found 9/6![United Airlines logo]()
$458
This Gotogate deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:05 am -
1 stop20h 45m
Sun 10/259:30 pm -
1 stop13h 53m
Deal found 9/3![Air Canada logo]()
$1,137
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/132:13 pm -
1 stop18h 12m
Mon 11/164:40 pm -
1 stop8h 31m
Deal found 9/7![Copa Airlines logo]()
$433
This GOL deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:06 pm -
2 stops29h 39m
Sat 9/2610:05 pm -
2 stops25h 33m
Deal found 9/5![GOL logo]()
$1,207
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:13 pm -
1 stop26h 13m
Wed 11/1812:08 pm -
1 stop13h 03m
Deal found 9/5![Copa Airlines logo]()
$433
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
2 stops12h 22m
Wed 12/212:55 am -
2 stops18h 31m
Deal found 9/7![Delta logo]()
$512
This Copa Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:35 am -
1 stop26h 32m
Sun 11/2210:40 am -
1 stop14h 31m
Deal found 9/8![Copa Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:45 pm -
1 stop31h 15m
Fri 10/2312:35 am -
1 stop19h 40m
Deal found 9/7![United Airlines logo]()
$537
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:33 pm -
2 stops22h 19m
Wed 11/1112:55 am -
2 stops20h 22m
Deal found 9/7![Delta logo]()
$512
This Arajet deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:30 am -
1 stop15h 35m
Thu 10/297:45 am -
1 stop17h 55m
Deal found 9/4![Arajet logo]()
$758
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:35 am -
1 stop26h 32m
Sun 11/14:40 pm -
1 stop8h 31m
Deal found 9/7![Copa Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:55 pm -
1 stop28h 35m
Fri 11/131:35 am -
1 stop19h 20m
Deal found 9/4![United Airlines logo]()
$537
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:30 am -
2 stops12h 22m
Tue 11/2412:55 am -
2 stops16h 23m
Deal found 9/4![Delta logo]()
$533
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:13 pm -
1 stop17h 02m
Tue 11/176:25 am -
1 stop18h 46m
Deal found 9/5![Copa Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:55 pm -
1 stop28h 35m
Sat 11/71:35 am -
1 stop10h 42m
Deal found 9/4![United Airlines logo]()
$537
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:20 am -
2 stops12h 45m
Thu 11/1212:55 am -
1 stop19h 10m
Deal found 9/5![Delta logo]()
$533
Last-minute flights from Chicago to South AmericaDiscover last-minute flight deals from Chicago to South America. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to South America. Data last updated September 9, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:30 am -
1 stop7h 45m
Thu 9/172:30 pm -
2 stops25h 43m
Deal found 9/6![Delta logo]()
$388
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:10 pm -
2 stops19h 55m
Sat 9/192:30 pm -
1 stop9h 29m
Deal found 9/7![Delta logo]()
$402
This Gotogate deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:01 am -
1 stop30h 04m
Wed 9/169:45 am -
1 stop15h 17m
Deal found 9/7![Copa Airlines logo]()
$417
This Trip.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:30 am -
1 stop8h 10m
Tue 9/222:55 pm -
1 stop9h 04m
Deal found 9/4![Delta logo]()
$436
This BusinessClass deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:57 pm -
2 stops17h 38m
Mon 9/281:35 pm -
2 stops19h 01m
Deal found 9/7![GOL logo]()
$432
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:20 pm -
1 stop16h 45m
Wed 10/1412:00 pm -
1 stop12h 57m
Deal found 9/5![Copa Airlines logo]()
$424
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:20 pm -
1 stop22h 45m
Mon 10/266:25 am -
1 stop18h 40m
Deal found 9/5![Copa Airlines logo]()
$405
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:20 pm -
1 stop25h 47m
Fri 10/304:40 pm -
1 stop8h 25m
Deal found 9/4![Copa Airlines logo]()
$413
This Gotogate deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:20 pm -
1 stop9h 02m
Thu 10/294:40 pm -
1 stop8h 25m
Deal found 9/7![Copa Airlines logo]()
$417
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2510:01 am -
1 stop12h 09m
Sun 11/13:15 pm -
1 stop9h 41m
Deal found 9/4![American Airlines logo]()
$437
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:35 am -
1 stop8h 28m
Sun 11/14:40 pm -
1 stop8h 31m
Deal found 9/8![Copa Airlines logo]()
$424
This Copa Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:13 pm -
1 stop9h 07m
Sat 11/712:08 pm -
1 stop13h 03m
Deal found 9/6![Copa Airlines logo]()
$433
One-way flights from Chicago to South AmericaSearch for one-way flight options from Chicago to South America. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Chicago to South America. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/185:30 am -
1 stop7h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$168
This LATAM Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:30 am -
1 stop7h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![LATAM Airlines logo]()
$172
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:01 am -
1 stop9h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Copa Airlines logo]()
$178
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:06 pm -
2 stops15h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![American Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/12:13 pm -
1 stop9h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Copa Airlines logo]()
$182
This eDestinos deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:30 am -
1 stop9h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Arajet logo]()
$184
This Copa Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:01 am -
1 stop9h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Copa Airlines logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:30 am -
1 stop7h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![LATAM Airlines logo]()
$186
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:13 pm -
1 stop17h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Copa Airlines logo]()
$188
This Cheapflightsfares deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:00 am -
1 stop6h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![JetBlue logo]()
$190
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:00 am -
1 stop8h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:13 pm -
1 stop9h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Copa Airlines logo]()
$191
Find flight deals from Chicago to South America
Keep the following information in mind while searching for Chicago to South America flight deals. Data was last updated September 9, 2026.
Round-trip from | $365 (Copa Airlines) |
|---|---|
One-way from | $168 (Delta) |
Popular in | December |
Cheapest in | February |
Average price | $467 |
Good round-trip deal | $470 or less |
Good one-way deal | $411 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Chicago to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Tue 1/19
5:30 am-2:10 pm
1 stop7h 40m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$168
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Sun 1/24
11:30 am-2:10 pm
2 stops25h 40m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$174
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Tue 11/24
2:13 pm-11:00 am
1 stop19h 47m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$178
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Mon 10/19
3:20 pm-11:00 pm
1 stop7h 40m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$179
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Wed 10/28
3:13 pm-8:35 am
1 stop17h 22m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$188
ChicagoCartagena
ORD Chicago O'Hare Intl - CTG Cartagena Rafael Nunez
ORDCTG
Chicago O'Hare Intl
Wed 11/25
2:13 pm-8:35 am
1 stop17h 22m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$193
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Mon 11/9
12:59 pm-11:05 pm
1 stop9h 06m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$194
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Fri 10/30
6:30 pm-5:10 am
1 stop10h 40m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$194
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Sat 11/14
2:13 pm-11:07 am
1 stop19h 54m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$195
ChicagoBogotá
ORD Chicago O'Hare Intl - BOG Bogotá El Dorado
ORDBOG
Chicago O'Hare Intl
Fri 10/23
3:20 pm-11:06 am
1 stop19h 46m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$195
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Chicago to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Chicago with our price prediction graph.
ORD-CTG
ORD-BOG
ORD-MDE
MDW-LIM
ORD-GRU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to South America
CHI-0SA
ORD-CTG
ORD-BOG
ORD-MDE
MDW-LIM
What is the cheapest month to book a flight from Chicago to South America?
Currently, February is the cheapest month in which you can book a flight from Chicago to South America (average of $537). Flying from Chicago to South America in December is currently the most expensive (average of $827). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to SA?
Find hourly flight availability from Chicago to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 9, 2026.
When flying from Chicago to South America, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 43% versus a flight in the afternoon.
Weekly flight availability from Chicago to South America
Explore weekly flight availability from Chicago to South America. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 9, 2026.
The most flights from CHI to 0SA are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).
How far ahead should I book a flight from Chicago to South America?
The price you pay for your flight from Chicago to South America may vary depending on when you book. For the best chance of a lower fare, look to book 34 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 9, 2026.
Read reviews from past customers who have flown Copa Airlines,LATAM Airlines, andUnited Airlines from Chicago to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Comfort
7.4
Boarding
7.8
Crew
8.1
Food
6.9
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Comfort
7.4
Boarding
7.8
Crew
8.1
Food
6.9
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Comfort
7.4
Boarding
7.8
Crew
8.1
Food
6.9
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Comfort
7.4
Boarding
7.8
Crew
8.1
Food
6.9
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Comfort
7.4
Boarding
7.8
Crew
8.1
Food
6.9
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.9
Comfort
7.4
Boarding
7.8
Crew
8.1
Food
6.9
Overall
7.6
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Chicago to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to South America by cabin class
Find flights from Chicago to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and South America flights
Browse other Chicago and South America flight options. Last updated on September 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Chicago to South America flights
Consider these flights traveling from Chicago to South America.
Top 10 airlines flying from Chicago to South America
Discover the top 10 airlines that operate flights from Chicago to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$153 | Average$791 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$161 | Average$653 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$185 | Average$726 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$204 | Average$797 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$269 | Average$715 | FlexibilityNo cancel fee | On-time74% | |
| Cheapest$272 | Average$717 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$272 | Average$623 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$298 | Average$641 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$317 | Average$838 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$319 | Average$735 | FlexibilityNo cancel fee | On-time67% |