$154+ Cheap flights from Missouri to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Missouri to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Panama City
Keep the following information in mind while searching for Missouri to Panama City flight deals. Data was last updated May 1, 2025.
Most accurate provider | AranGrant 3 stars |
|---|---|
Most trusted provider | AranGrant 3 stars |
Round-trip from | $398 (United Airlines) |
One-way from | $154 (United Airlines) |
Popular in | December |
Cheapest in | April |
Average price | $615 |
Find flight deals from Missouri to Panama City
Cheapest flights from Missouri to Panama CityExplore the most affordable flight options available from Missouri to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.
Explore the most affordable flight options available from Missouri to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Ovago deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Missouri to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Thu 6/26
10:15 am-2:14 pm
1 stop27h 59m
Panama City Tocumen Intl
Mon 6/30
3:30 pm-9:31 am
1 stop18h 01m
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Sat 6/14
10:05 am-7:02 pm
1 stop8h 57m
Panama City Tocumen Intl
Sat 6/21
8:10 am-4:25 pm
1 stop8h 15m
Kansas CityPanama City
MCI - PTY
MCIPTY
Kansas City
Fri 7/4
8:10 am-7:02 pm
1 stop10h 52m
Panama City Tocumen Intl
Tue 7/15
2:23 pm-10:56 pm
1 stop8h 33m
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Sat 6/14
5:25 am-2:25 pm
1 stop9h 00m
Panama City Tocumen Intl
Sat 6/21
1:50 pm-8:13 am
2 stops18h 23m
Kansas CityPanama City
MCI - PTY
MCIPTY
Kansas City
Fri 7/4
3:28 pm-2:14 pm
2 stops22h 46m
Panama City Tocumen Intl
Tue 7/15
10:00 am-10:00 pm
1 stop12h 00m
Kansas CityPanama City
MCI - PTY
MCIPTY
Kansas City
Wed 5/21
1:48 pm-12:19 pm
2 stops22h 31m
Panama City Tocumen Intl
Wed 5/28
1:20 pm-10:38 pm
1 stop9h 18m
Kansas CityPanama City
MCI - PTY
MCIPTY
Kansas City
Sun 6/15
6:05 am-12:45 am
3 stops42h 40m
Panama City Tocumen Intl
Sat 6/21
3:20 am-10:10 am
3 stops30h 50m
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Sat 5/24
10:10 am-8:19 pm
1 stop10h 09m
Panama City Tocumen Intl
Sun 5/25
3:20 am-11:52 pm
2 stops20h 32m
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Sat 8/23
8:15 am-12:10 am
2 stops15h 55m
Panama City Tocumen Intl
Sat 8/30
3:20 am-6:59 pm
2 stops15h 39m
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Tue 6/3
5:00 am-6:37 pm
2 stops13h 37m
Best time to book a flight from Missouri to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Missouri with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Panama City
What is the cheapest month to book a flight from Missouri to Panama City?
Currently, October is the cheapest month in which you can book a flight from Missouri to Panama City (average of $478). Flying from Missouri to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to PTY?
Find hourly flight availability from Missouri to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Panama City as you normally would.
Rainfall in Panama City by month
Plan your trip to Panama City by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.
Temperature in Panama City by month
Plan your trip to Panama City by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated May 1, 2025.
See what other customers who have flown with Delta, United Airlines and American Airlines from Missouri to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
Entertainment
Food
Overall
Boarding
Crew
Reviews
Aaron,Oct 2024
LAX - LHR
Comfort
Entertainment
Food
Overall
Boarding
Crew
Reviews
Aaron,Oct 2024
LAX - LHR
Comfort
Entertainment
Food
Overall
Boarding
Crew
Reviews
Aaron,Oct 2024
LAX - LHR
Comfort
Entertainment
Food
Overall
Boarding
Crew
Reviews
Aaron,Oct 2024
LAX - LHR
Comfort
Entertainment
Food
Overall
Boarding
Crew
Reviews
Aaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from Missouri to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Top 3 airlines flying from Missouri to Panama City
Discover the top 3 airlines that operate flights from Missouri to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$379 | Average$568 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$397 | Average$567 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$440 | Average$573 | FlexibilityNo cancel fee | On-time71% |