$350+ Cheap flights from Missouri to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/25. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — PTY
Jul 8 — Jul 151
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to PanamaExplore the most affordable flight options available from Missouri to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
Explore the most affordable flight options available from Missouri to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:20 am
MCI
- PTY
1 stop7h 54m
United Airlines
Wed 8/193:30 pm
PTY
- MCI
2 stops17h 28m
United Airlines
Deal found 6/4![United Airlines logo]()
$521
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:20 am
MCI
- PTY
1 stop12h 17m
United Airlines
Mon 8/2410:00 am
PTY
- MCI
1 stop12h 35m
United Airlines
Deal found 6/8![United Airlines logo]()
$527
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:08 pm
MCI
- PTY
2 stops21h 06m
United Airlines
Wed 8/193:30 pm
PTY
- MCI
2 stops22h 48m
United Airlines
Deal found 6/7![United Airlines logo]()
$531
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:20 pm
MCI
- PTY
1 stop21h 52m
United Airlines
Wed 7/299:45 am
PTY
- MCI
1 stop14h 14m
United Airlines
Deal found 6/6![United Airlines logo]()
$536
This KAYAK deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:30 am
MCI
- PTY
1 stop10h 07m
Copa Airlines
Wed 8/193:30 pm
PTY
- MCI
1 stop25h 22m
Copa Airlines
Deal found 6/4![Copa Airlines logo]()
$537
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:16 am
MCI
- PTY
1 stop12h 21m
United Airlines
Wed 7/299:45 am
PTY
- MCI
1 stop14h 14m
United Airlines
Deal found 6/4![United Airlines logo]()
$552
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:01 am
STL
- PTY
1 stop13h 30m
United Airlines
Wed 7/159:45 am
PTY
- STL
1 stop13h 59m
United Airlines
Deal found 6/5![United Airlines logo]()
$575
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:59 pm
STL
- PTY
2 stops22h 13m
United Airlines
Mon 8/1010:55 pm
PTY
- STL
2 stops16h 43m
United Airlines
Deal found 6/4![United Airlines logo]()
$579
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:01 am
STL
- PTY
1 stop22h 03m
United Airlines
Wed 7/297:55 am
PTY
- STL
1 stop14h 50m
United Airlines
Deal found 6/8![United Airlines logo]()
$585
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:59 pm
STL
- PTY
2 stops22h 13m
United Airlines
Mon 7/2710:55 pm
PTY
- STL
2 stops16h 51m
United Airlines
Deal found 6/5![United Airlines logo]()
$589
This Kissandfly.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:01 am
STL
- PTY
1 stop13h 30m
Lufthansa
Wed 7/157:55 am
PTY
- STL
1 stop14h 50m
Lufthansa
Deal found 6/5![Lufthansa logo]()
$591
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3111:10 am
STL
- PTY
1 stop7h 27m
United Airlines
Tue 8/49:45 am
PTY
- STL
1 stop13h 51m
United Airlines
Deal found 6/4![United Airlines logo]()
$592
Best flights from Missouri to PanamaDiscover carefully curated flight deals from Missouri to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
Discover carefully curated flight deals from Missouri to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:08 pm
MCI
- PTY
2 stops21h 06m
United Airlines
Wed 8/193:30 pm
PTY
- MCI
2 stops22h 48m
United Airlines
Deal found 6/7![United Airlines logo]()
$531
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
STL
- PTY
1 stop6h 55m
Delta
Fri 8/212:20 pm
PTY
- STL
1 stop9h 38m
Delta
Deal found 6/8![Delta logo]()
$592
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:18 am
STL
- PTY
1 stop6h 56m
American Airlines
Fri 7/101:14 pm
PTY
- STL
1 stop9h 40m
American Airlines
Deal found 6/3![American Airlines logo]()
$592
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:19 am
MCI
- PTY
1 stop12h 18m
United Airlines
Mon 10/263:41 pm
PTY
- MCI
2 stops18h 52m
United Airlines
Deal found 6/6![United Airlines logo]()
$531
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:16 am
MCI
- PTY
1 stop12h 21m
United Airlines
Mon 7/273:30 pm
PTY
- MCI
2 stops22h 50m
United Airlines
Deal found 6/7![United Airlines logo]()
$561
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:01 am
STL
- PTY
1 stop13h 30m
United Airlines
Wed 7/1510:55 pm
PTY
- STL
2 stops13h 16m
United Airlines
Deal found 6/7![United Airlines logo]()
$579
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:12 pm
SGF
- PTY
2 stops18h 02m
American Airlines
Mon 8/31:14 pm
PTY
- SGF
2 stops24h 26m
American Airlines
Deal found 6/7![American Airlines logo]()
$727
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
STL
- PTY
2 stops22h 04m
United Airlines
Wed 7/293:30 pm
PTY
- STL
2 stops20h 41m
United Airlines
Deal found 6/6![United Airlines logo]()
$579
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:34 pm
SGF
- PTY
2 stops17h 40m
American Airlines
Sat 7/111:14 pm
PTY
- SGF
1 stop9h 28m
American Airlines
Deal found 6/8![American Airlines logo]()
$747
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:59 pm
STL
- PTY
2 stops22h 13m
United Airlines
Mon 8/103:30 pm
PTY
- STL
2 stops20h 32m
United Airlines
Deal found 6/8![United Airlines logo]()
$579
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:36 pm
STL
- PTY
2 stops20h 38m
United Airlines
Wed 10/213:30 pm
PTY
- STL
2 stops24h 13m
United Airlines
Deal found 6/3![United Airlines logo]()
$579
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:16 am
MCI
- PTY
1 stop9h 56m
United Airlines
Thu 6/2510:00 am
PTY
- MCI
1 stop12h 31m
United Airlines
Deal found 6/8![United Airlines logo]()
$587
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:01 am
STL
- PTY
1 stop13h 30m
United Airlines
Mon 7/2710:55 pm
PTY
- STL
2 stops16h 51m
United Airlines
Deal found 6/5![United Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/99:34 am
MCI
- PTY
2 stops18h 30m
United Airlines
Mon 7/133:30 pm
PTY
- MCI
2 stops20h 52m
United Airlines
Deal found 6/4![United Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3111:10 am
STL
- PTY
1 stop7h 27m
United Airlines
Tue 8/49:45 am
PTY
- STL
1 stop13h 51m
United Airlines
Deal found 6/4![United Airlines logo]()
$592
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:30 am
MCI
- PTY
1 stop10h 07m
United Airlines
Sat 9/59:45 am
PTY
- MCI
1 stop14h 14m
United Airlines
Deal found 6/5![United Airlines logo]()
$595
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:05 am
MCI
- PTY
1 stop13h 26m
United Airlines
Fri 7/2410:55 pm
PTY
- MCI
1 stop18h 07m
United Airlines
Deal found 6/4![United Airlines logo]()
$620
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:30 am
MCI
- PTY
1 stop10h 07m
United Airlines
Mon 7/207:55 am
PTY
- MCI
1 stop14h 36m
United Airlines
Deal found 6/4![United Airlines logo]()
$621
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:16 am
MCI
- PTY
1 stop7h 58m
United Airlines
Sun 7/269:45 am
PTY
- MCI
1 stop14h 14m
United Airlines
Deal found 6/8![United Airlines logo]()
$621
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:25 pm
SGF
- PTY
2 stops25h 06m
United Airlines
Sat 10/243:30 pm
PTY
- SGF
2 stops19h 04m
United Airlines
Deal found 6/7![United Airlines logo]()
$661
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:15 am
SGF
- PTY
1 stop12h 22m
United Airlines
Mon 10/267:55 am
PTY
- SGF
1 stop11h 48m
United Airlines
Deal found 6/6![United Airlines logo]()
$673
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:15 am
SGF
- PTY
1 stop7h 59m
United Airlines
Fri 7/243:30 pm
PTY
- SGF
2 stops19h 14m
United Airlines
Deal found 6/5![United Airlines logo]()
$691
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:35 am
SGF
- PTY
1 stop12h 03m
United Airlines
Wed 11/48:55 am
PTY
- SGF
1 stop8h 08m
United Airlines
Deal found 6/3![United Airlines logo]()
$703
Last-minute flights from Missouri to PanamaDiscover last-minute flight deals from Missouri to Panama. Data last updated June 8, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Panama. Data last updated June 8, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:16 am
MCI
- PTY
1 stop12h 21m
United Airlines
Wed 7/299:45 am
PTY
- MCI
1 stop14h 14m
United Airlines
Deal found 6/4![United Airlines logo]()
$552
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:14 am
STL
- PTY
1 stop12h 23m
United Airlines
Fri 7/1010:55 pm
PTY
- STL
1 stop17h 12m
United Airlines
Deal found 6/4![United Airlines logo]()
$619
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:14 am
STL
- PTY
1 stop12h 23m
United Airlines
Sat 7/117:55 am
PTY
- STL
1 stop14h 50m
United Airlines
Deal found 6/4![United Airlines logo]()
$609
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:16 am
MCI
- PTY
1 stop12h 21m
United Airlines
Mon 7/133:30 pm
PTY
- MCI
1 stop18h 33m
United Airlines
Deal found 6/4![United Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:01 am
STL
- PTY
1 stop13h 30m
United Airlines
Wed 7/159:45 am
PTY
- STL
1 stop13h 59m
United Airlines
Deal found 6/5![United Airlines logo]()
$575
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:16 am
MCI
- PTY
1 stop7h 58m
United Airlines
Mon 7/133:30 pm
PTY
- MCI
1 stop18h 33m
United Airlines
Deal found 6/4![United Airlines logo]()
$587
This Kissandfly.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:01 am
STL
- PTY
1 stop13h 30m
Lufthansa
Wed 7/157:55 am
PTY
- STL
1 stop14h 50m
Lufthansa
Deal found 6/5![Lufthansa logo]()
$591
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:01 am
STL
- PTY
1 stop13h 30m
United Airlines
Mon 7/2710:55 pm
PTY
- STL
2 stops16h 51m
United Airlines
Deal found 6/5![United Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:16 am
MCI
- PTY
1 stop7h 58m
United Airlines
Sun 7/269:45 am
PTY
- MCI
1 stop14h 14m
United Airlines
Deal found 6/5![United Airlines logo]()
$596
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:01 am
STL
- PTY
1 stop22h 03m
United Airlines
Wed 7/297:55 am
PTY
- STL
1 stop14h 50m
United Airlines
Deal found 6/8![United Airlines logo]()
$585
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:41 pm
MCI
- PTY
2 stops19h 33m
United Airlines
Wed 7/2910:55 pm
PTY
- MCI
2 stops18h 41m
United Airlines
Deal found 6/6![United Airlines logo]()
$531
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3111:10 am
STL
- PTY
1 stop7h 27m
United Airlines
Tue 8/43:30 pm
PTY
- STL
1 stop18h 37m
United Airlines
Deal found 6/8![United Airlines logo]()
$592
One-way flights from Missouri to PanamaSearch for one-way flight options from Missouri to Panama. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
Search for one-way flight options from Missouri to Panama. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:12 pm
SGF
- PTY
2 stops18h 01m
American Airlines
Deal found 6/3![American Airlines logo]()
$350
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:00 am
STL
- PTY
2 stops12h 37m
United Airlines
Deal found 6/4![United Airlines logo]()
$382
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/147:05 pm
STL
- PTY
2 stops19h 09m
United Airlines
Deal found 6/8![United Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/253:05 pm
SGF
- PTY
1 stop23h 09m
United Airlines
Deal found 6/3![United Airlines logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:08 pm
STL
- PTY
3 stops28h 27m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$449
This Faresmojo deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:38 am
MCI
- PTY
1 stop7h 31m
JetBlue
Deal found 6/4![JetBlue logo]()
$514
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/211:45 pm
MCI
- PTY
3 stops34h 50m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$536
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/218:30 am
MCI
- PTY
1 stop10h 07m
United Airlines
Deal found 6/5![United Airlines logo]()
$537
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/147:03 pm
STL
- PTY
3 stops29h 32m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$566
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:57 pm
SGF
- PTY
3 stops47h 22m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$581
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:17 pm
MCI
- PTY
2 stops18h 56m
American Airlines
Deal found 6/5![American Airlines logo]()
$584
This KAYAK deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:17 pm
MCI
- PTY
2 stops18h 56m
GOL
Deal found 6/4![GOL logo]()
$586
Find flight deals from Missouri to Panama
Keep the following information in mind while searching for Missouri to Panama flight deals. Data was last updated June 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $521 (United Airlines) |
One-way from | $350 (American Airlines) |
Popular in | December |
Cheapest in | April |
Average price | $631 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
Use the filters below to find and compare flights from Missouri to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityPanama City
MCI - PTY
MCIPTY
Kansas City
Sun 8/16
5:08 pm-2:14 pm
2 stops21h 06m
Panama City Tocumen Intl
Wed 8/19
3:30 pm-2:18 pm
2 stops22h 48m
$531
Kansas CityPanama City
MCI - PTY
MCIPTY
Kansas City
Thu 10/22
6:19 am-6:37 pm
1 stop12h 18m
Panama City Tocumen Intl
Mon 10/26
3:41 pm-10:33 am
2 stops18h 52m
$531
Kansas CityPanama City
MCI - PTY
MCIPTY
Kansas City
Mon 7/20
6:16 am-6:37 pm
1 stop12h 21m
Panama City Tocumen Intl
Mon 7/27
3:30 pm-2:20 pm
2 stops22h 50m
$561
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Thu 7/9
6:01 am-7:31 pm
1 stop13h 30m
Panama City Tocumen Intl
Wed 7/15
10:55 pm-12:11 pm
2 stops13h 16m
$579
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Thu 7/23
6:00 am-4:04 am
2 stops22h 04m
Panama City Tocumen Intl
Wed 7/29
3:30 pm-12:11 pm
2 stops20h 41m
$579
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Sun 8/2
5:59 pm-4:12 pm
2 stops22h 13m
Panama City Tocumen Intl
Mon 8/10
3:30 pm-12:02 pm
2 stops20h 32m
$579
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Mon 10/19
5:36 pm-2:14 pm
2 stops20h 38m
Panama City Tocumen Intl
Wed 10/21
3:30 pm-3:43 pm
2 stops24h 13m
$579
Kansas CityPanama City
MCI - PTY
MCIPTY
Kansas City
Tue 6/23
6:16 am-4:12 pm
1 stop9h 56m
Panama City Tocumen Intl
Thu 6/25
10:00 am-10:31 pm
1 stop12h 31m
$587
St. LouisPanama City
STL - PTY
STLPTY
Lambert-St Louis
Mon 7/20
6:01 am-7:31 pm
1 stop13h 30m
Panama City Tocumen Intl
Mon 7/27
10:55 pm-3:46 pm
2 stops16h 51m
$589
Kansas CityPanama City
MCI - PTY
MCIPTY
Kansas City
Thu 7/9
9:34 am-4:04 am
2 stops18h 30m
Panama City Tocumen Intl
Mon 7/13
3:30 pm-12:22 pm
2 stops20h 52m
$591
Showing 1-10 of 36 resultsSorted by cheapest first
Best time to book a flight from Missouri to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Missouri with our price prediction graph.
MCI-PTY
STL-PTY
SGF-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Panama
USMO-PA0
MCI-PTY
STL-PTY
SGF-PTY
What is the cheapest month to book a flight from Missouri to Panama?
Currently, February is the cheapest month in which you can book a flight from Missouri to Panama (average of $174). Flying from Missouri to Panama in September is currently the most expensive (average of $513). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
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Top destinations
Alternative routes for Missouri to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Panama by cabin class
Find flights from Missouri to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Panama flights
Browse other Missouri and Panama flight options. Last updated on June 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Panama
Find the right flight back to Missouri after your stay in Panama
Missouri to Panama flights
Consider these flights traveling from Missouri to Panama.
Top 3 airlines flying from Missouri to Panama
Discover the top 3 airlines that operate flights from Missouri to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$393 | Average$607 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$393 | Average$642 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$408 | Average$568 | FlexibilityNo cancel fee | On-timeN/A |