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Panama City

$222+ Cheap flights from Mississippi to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — PTY
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Mississippi to Panama City

Keep the following information in mind while searching for Mississippi to Panama City flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$422
(United Airlines)

One-way from

$222
(Delta)
Provider with most accurate pricing for Jackson-Evers Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Panama City Tocumen Intl flights.
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From Mississippi to Panama City Tocumen Intl
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One-way flight from Mississippi to Panama City Tocumen Intl
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Find flight deals from Mississippi to Panama City

Cheapest flights from Mississippi to Panama City
Explore the most affordable flight options available from Mississippi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/235:25 pmGPT - PTY
1 stop22h 47mUnited Airlines
Mon 7/287:55 amPTY - GPT
1 stop8h 19mUnited Airlines
Deal found 4/30$422
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/239:10 amMOB - PTY
1 stop9h 27mUnited Airlines
Sun 7/273:30 pmPTY - MOB
1 stop30h 05mUnited Airlines
Deal found 4/30$438
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/236:36 pmGPT - PTY
2 stops18h 18mAmerican Airlines
Mon 7/283:10 pmPTY - GPT
2 stops26h 50mAmerican Airlines
Deal found 4/30$480
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/211:43 amMEM - PTY
1 stop6h 54mUnited Airlines
Wed 7/210:00 amPTY - MEM
1 stop12h 14mUnited Airlines
Deal found 4/30$489
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:51 amMEM - PTY
1 stop6h 28mAmerican Airlines
Thu 7/31:50 pmPTY - MEM
2 stops19h 55mAmerican Airlines
Deal found 4/30$494
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/135:00 pmJAN - PTY
2 stops21h 25mAmerican Airlines
Sun 6/153:20 pmPTY - JAN
2 stops20h 59mAmerican Airlines
Deal found 4/29$500
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/139:00 amJAN - PTY
1 stop9h 37mUnited Airlines
Sun 6/153:30 pmPTY - JAN
1 stop19h 59mUnited Airlines
Deal found 4/29$503
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/46:00 amMEM - PTY
1 stop6h 48mDelta
Tue 7/12:23 pmPTY - MEM
1 stop21h 00mDelta
Deal found 4/30$517
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/126:51 pmMOB - PTY
2 stops17h 28mAmerican Airlines
Sun 5/181:20 pmPTY - MOB
2 stops22h 50mAmerican Airlines
Deal found 4/30$550
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/149:45 amBTR - PTY
1 stop8h 52mUnited Airlines
Sat 6/213:30 pmPTY - BTR
1 stop17h 29mUnited Airlines
Deal found 4/30$571
This United deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/142:01 pmGPT - PTY
2 stops22h 34mMultiple Airlines
Sun 5/1810:00 amPTY - GPT
1 stop9h 46mMultiple Airlines
Deal found 4/30$735
This Avianca Connect deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:00 amMEM - PTY
2 stops19h 10mMultiple Airlines
Sun 10/53:20 amPTY - MEM
2 stops19h 37mMultiple Airlines
Deal found 4/30$741

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Mississippi to Panama City that are best for you.

Fly from

Mississippi

Fly to

Panama City

Route

Depart

Return

Price

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Wed 7/23

5:25 pm-4:12 pm

1 stop22h 47m

Panama City Tocumen Intl

Mon 7/28

7:55 am-4:14 pm

1 stop8h 19m

$422

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Wed 7/23

9:10 am-6:37 pm

1 stop9h 27m

Panama City Tocumen Intl

Sun 7/27

3:30 pm-9:35 pm

1 stop30h 05m

$438

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

Wed 7/23

6:36 pm-12:54 pm

2 stops18h 18m

Panama City Tocumen Intl

Mon 7/28

3:10 pm-6:00 pm

2 stops26h 50m

$480

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Mon 6/2

11:43 am-6:37 pm

1 stop6h 54m

Panama City Tocumen Intl

Wed 7/2

10:00 am-10:14 pm

1 stop12h 14m

$489

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Wed 5/28

5:51 am-12:19 pm

1 stop6h 28m

Panama City Tocumen Intl

Thu 7/3

1:50 pm-9:45 am

2 stops19h 55m

$494

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Fri 6/13

5:00 pm-2:25 pm

2 stops21h 25m

Panama City Tocumen Intl

Sun 6/15

3:20 pm-12:19 pm

2 stops20h 59m

$500

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Fri 6/13

9:00 am-6:37 pm

1 stop9h 37m

Panama City Tocumen Intl

Sun 6/15

3:30 pm-11:29 am

1 stop19h 59m

$503

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Wed 6/4

6:00 am-12:48 pm

1 stop6h 48m

Panama City Tocumen Intl

Tue 7/1

2:23 pm-11:23 am

1 stop21h 00m

$517

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Mon 5/12

6:51 pm-12:19 pm

2 stops17h 28m

Panama City Tocumen Intl

Sun 5/18

1:20 pm-12:10 pm

2 stops22h 50m

$550

Baton RougePanama City

BTR - PTY

BTRPTY

Baton Rouge Ryan

Sat 6/14

9:45 am-6:37 pm

1 stop8h 52m

Panama City Tocumen Intl

Sat 6/21

3:30 pm-8:59 am

1 stop17h 29m

$571

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 17 results
1
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Best time to book a flight from Mississippi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Panama City

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated May 1, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Mississippi to Panama City. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Mississippi?

    Most people fly into Panama City Tocumen Intl (PTY) if they book a flight to Panama City from Mississippi. Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • What are the cheapest airlines to fly from Mississippi to Panama City one-way?

    The cheapest airlines for a one-way flight from Mississippi to Panama City are Delta ($222), United Airlines ($243), and American Airlines ($301).

  • What are the most popular routes from Mississippi to Panama City?

    While some choose either Jackson-Evers Intl - Panama City Tocumen Intl or Gulfport Biloxi Regional - Panama City Tocumen Intl, Memphis - Panama City Tocumen Intl is the most popular route from Mississippi to Panama City.

  • Can I find deals for flights from Mississippi to Panama City that include hotel bookings?

    Yes. In addition to deals on Mississippi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Panama City.

  • Can I find deals for business class flights from Mississippi to Panama City?

    Yes. Cheapflights offers flight deals from Mississippi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Mississippi to Panama City (average of $478). Flying from Mississippi to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Panama City

Discover the top 2 airlines that operate flights from Mississippi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$377Average$417FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$384Average$569FlexibilityNo cancel feeOn-time69%

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