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Panama City

$252+ Cheap flights from Mississippi to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — PTY
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Mississippi to Panama City

Keep the following information in mind while searching for Mississippi to Panama City flight deals. Data was last updated June 12, 2025.

Round-trip from

$420
(Delta)

One-way from

$252
(United Airlines)
From Mississippi to Panama City Tocumen Intl
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One-way flight from Mississippi to Panama City Tocumen Intl
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Find flight deals from Mississippi to Panama City

Cheapest flights from Mississippi to Panama City
Explore the most affordable flight options available from Mississippi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/17:30 amMEM - PTY
1 stop12h 01mDelta
Sat 8/92:28 pmPTY - MEM
1 stop17h 22mDelta
Deal found 6/11$420
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/277:00 amJAN - PTY
1 stop6h 45mUnited Airlines
Mon 11/108:55 amPTY - JAN
1 stop11h 46mUnited Airlines
Deal found 6/10$467
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/319:00 amMEM - PTY
1 stop7h 12mUnited Airlines
Thu 8/77:55 amPTY - MEM
1 stop12h 17mUnited Airlines
Deal found 6/11$489
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/13:43 pmMEM - PTY
2 stops21h 11mAmerican Airlines
Mon 8/43:10 pmPTY - MEM
2 stops18h 37mAmerican Airlines
Deal found 6/11$494
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/276:52 pmJAN - PTY
2 stops17h 33mAmerican Airlines
Mon 11/104:20 pmPTY - JAN
2 stops18h 56mAmerican Airlines
Deal found 6/10$501
This Avianca Connect deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:00 amMEM - PTY
2 stops19h 10mMultiple Airlines
Sat 9/273:20 amPTY - MEM
2 stops19h 37mMultiple Airlines
Deal found 6/10$518
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/269:10 amMOB - PTY
1 stop9h 27mUnited Airlines
Sat 8/23:30 pmPTY - MOB
1 stop30h 05mUnited Airlines
Deal found 6/11$535
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2612:10 pmBTR - PTY
1 stop6h 27mUnited Airlines
Tue 9/303:30 pmPTY - BTR
1 stop7h 52mUnited Airlines
Deal found 6/10$551
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/266:01 pmMOB - PTY
2 stops20h 14mAmerican Airlines
Sat 8/23:10 pmPTY - MOB
2 stops26h 21mAmerican Airlines
Deal found 6/11$552
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/112:56 pmBTR - PTY
2 stops23h 58mAmerican Airlines
Fri 8/83:30 pmPTY - BTR
2 stops26h 38mAmerican Airlines
Deal found 6/10$556
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/16:10 amBTR - PTY
1 stop7h 03mDelta
Fri 8/82:28 pmPTY - BTR
1 stop7h 30mDelta
Deal found 6/10$571
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/239:10 amGPT - PTY
1 stop7h 02mUnited Airlines
Sat 7/263:30 pmPTY - GPT
1 stop21h 58mUnited Airlines
Deal found 6/10$1,048

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Mississippi to Panama City that are best for you.

Fly from

Mississippi

Fly to

Panama City

Route

Depart

Return

Price

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Fri 8/1

6:26 am-1:13 pm

1 stop6h 47m

Panama City Tocumen Intl

Sun 8/3

2:28 pm-11:44 pm

1 stop9h 16m

$420

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Thu 7/31

7:00 am-6:37 pm

1 stop11h 37m

Panama City Tocumen Intl

Wed 8/6

10:00 am-10:14 pm

1 stop12h 14m

$489

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Fri 8/1

3:43 pm-12:54 pm

2 stops21h 11m

Panama City Tocumen Intl

Mon 8/4

3:10 pm-9:47 am

2 stops18h 37m

$494

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Thu 9/25

5:00 am-12:10 am

2 stops19h 10m

Panama City Tocumen Intl

Sat 9/27

3:20 am-10:57 pm

2 stops19h 37m

$518

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Sat 7/19

9:00 am-6:37 pm

1 stop9h 37m

Panama City Tocumen Intl

Thu 7/24

10:00 am-9:59 pm

1 stop11h 59m

$527

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Sat 7/26

9:10 am-6:37 pm

1 stop9h 27m

Panama City Tocumen Intl

Sat 8/2

3:30 pm-9:35 pm

1 stop30h 05m

$535

Baton RougePanama City

BTR - PTY

BTRPTY

Baton Rouge Ryan

Fri 9/26

12:10 pm-6:37 pm

1 stop6h 27m

Panama City Tocumen Intl

Tue 9/30

3:30 pm-11:22 pm

1 stop7h 52m

$551

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Sat 7/26

6:01 pm-2:15 pm

2 stops20h 14m

Panama City Tocumen Intl

Sat 8/2

3:10 pm-5:31 pm

2 stops26h 21m

$552

Baton RougePanama City

BTR - PTY

BTRPTY

Baton Rouge Ryan

Fri 8/1

12:56 pm-12:54 pm

2 stops23h 58m

Panama City Tocumen Intl

Fri 8/8

3:30 pm-6:08 pm

2 stops26h 38m

$556

Baton RougePanama City

BTR - PTY

BTRPTY

Baton Rouge Ryan

Fri 8/1

6:10 am-1:13 pm

1 stop7h 03m

Panama City Tocumen Intl

Fri 8/8

2:28 pm-9:58 pm

1 stop7h 30m

$571

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 18 results
1
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Best time to book a flight from Mississippi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Panama City

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated June 12, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Mississippi to Panama City. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Mississippi?

    Most people fly into Panama City Tocumen Intl (PTY) if they book a flight to Panama City from Mississippi. Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • What are the cheapest airlines to fly from Mississippi to Panama City one-way?

    The cheapest airlines for a one-way flight from Mississippi to Panama City are United Airlines ($252), Delta ($272), and American Airlines ($448).

  • What are the most popular routes from Mississippi to Panama City?

    While some choose either Baton Rouge Ryan - Panama City Tocumen Intl or Gulfport Biloxi Regional - Panama City Tocumen Intl, Memphis - Panama City Tocumen Intl is the most popular route from Mississippi to Panama City.

  • Can I find deals for flights from Mississippi to Panama City that include hotel bookings?

    Yes. In addition to deals on Mississippi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Panama City.

  • Can I find deals for business class flights from Mississippi to Panama City?

    Yes. Cheapflights offers flight deals from Mississippi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Mississippi to Panama City (average of $478). Flying from Mississippi to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Panama City

Discover the top 2 airlines that operate flights from Mississippi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$377Average$417FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$417Average$570FlexibilityNo cancel feeOn-time69%

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