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Panama City

$217+ Cheap flights from Mississippi to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — PTY
nov. 12 — nov. 191
mié. 11/12
mié. 11/19
1 adult, Economy
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Cheap flight deals from Mississippi to Panama City

Keep the following information in mind while searching for Mississippi to Panama City flight deals. Data was last updated octubre 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$468
(United Airlines)

One-way from

$217
(Mytrip)
Provider with most accurate pricing for Jackson-Evers Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Panama City Tocumen Intl flights.
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From Mississippi to Panama City Tocumen Intl
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One-way flight from Mississippi to Panama City Tocumen Intl
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Find flight deals from Mississippi to Panama City

Cheapest flights from Mississippi to Panama City
Explore the most affordable flight options available from Mississippi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 13, 2025.

This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/211:30 amMOB - PTY
1 stop7h 08mUnited Airlines
mié. 12/108:55 amPTY - MOB
1 stop8h 12mUnited Airlines
Deal found 10/12$468
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/22:50 pmMOB - PTY
2 stops23h 52mAmerican Airlines
mié. 12/102:50 pmPTY - MOB
2 stops20h 05mAmerican Airlines
Deal found 10/12$490
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/105:47 amMEM - PTY
1 stop7h 00mAmerican Airlines
vie. 2/134:40 pmPTY - MEM
1 stop7h 34mAmerican Airlines
Deal found 10/11$490
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/257:00 amMOB - PTY
1 stop11h 38mUnited Airlines
mar. 12/24:41 pmPTY - MOB
1 stop26h 41mUnited Airlines
Deal found 10/11$495
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/65:40 amJAN - PTY
1 stop13h 19mDelta
dom. 12/148:05 amPTY - JAN
1 stop11h 24mDelta
Deal found 10/13$508
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/256:00 amMEM - PTY
1 stop6h 43mAmerican Airlines
mar. 12/22:43 pmPTY - MEM
1 stop10h 16mAmerican Airlines
Deal found 10/10$510
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/195:30 pmMOB - PTY
2 stops19h 13mAmerican Airlines
mié. 11/262:43 pmPTY - MOB
2 stops20h 37mAmerican Airlines
Deal found 10/11$512
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/63:04 pmJAN - PTY
2 stops23h 38mAmerican Airlines
sáb. 12/134:43 pmPTY - JAN
2 stops19h 58mAmerican Airlines
Deal found 10/13$512
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/115:18 pmJAN - PTY
1 stop25h 20mUnited Airlines
mar. 11/188:55 amPTY - JAN
1 stop14h 04mUnited Airlines
Deal found 10/12$515
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/66:31 pmJAN - PTY
2 stops20h 11mAmerican Airlines
dom. 12/142:50 pmPTY - JAN
2 stops18h 50mAmerican Airlines
Deal found 10/13$517
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/116:00 amMEM - PTY
1 stop6h 49mAmerican Airlines
mar. 11/252:43 pmPTY - MEM
1 stop10h 16mAmerican Airlines
Deal found 10/11$530
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/2612:09 pmGPT - PTY
2 stops24h 34mAmerican Airlines
lun. 12/12:43 pmPTY - GPT
2 stops27h 56mAmerican Airlines
Deal found 10/11$531

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 13, 2025.
Use the filters below to find and compare flights from Mississippi to Panama City that are best for you.

Fly from

Mississippi

Fly to

Panama City

Route

Depart

Return

Price

MobilePanama City

MOB - PTY

MOBPTY

Mobile

mar. 12/2

11:30 am-7:38 pm

1 stop7h 08m

Panama City Tocumen Intl

mié. 12/10

8:55 am-4:07 pm

1 stop8h 12m

$468

MobilePanama City

MOB - PTY

MOBPTY

Mobile

mar. 12/2

2:50 pm-3:42 pm

2 stops23h 52m

Panama City Tocumen Intl

mié. 12/10

2:50 pm-9:55 am

2 stops20h 05m

$490

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

mié. 12/10

5:47 am-1:47 pm

1 stop7h 00m

Panama City Tocumen Intl

vie. 2/13

4:40 pm-11:14 pm

1 stop7h 34m

$490

MobilePanama City

MOB - PTY

MOBPTY

Mobile

mar. 11/25

7:00 am-7:38 pm

1 stop11h 38m

Panama City Tocumen Intl

mar. 12/2

4:41 pm-6:22 pm

1 stop26h 41m

$495

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

sáb. 12/6

5:40 am-7:59 pm

1 stop13h 19m

Panama City Tocumen Intl

dom. 12/14

8:05 am-6:29 pm

1 stop11h 24m

$508

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

sáb. 12/6

10:07 am-7:59 pm

1 stop8h 52m

Panama City Tocumen Intl

sáb. 12/13

8:05 am-5:21 pm

1 stop10h 16m

$508

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

mié. 11/26

6:45 am-7:38 pm

1 stop11h 53m

Panama City Tocumen Intl

mié. 12/3

11:35 am-10:21 pm

1 stop11h 46m

$510

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

mar. 11/25

6:00 am-1:43 pm

1 stop6h 43m

Panama City Tocumen Intl

mar. 12/2

2:43 pm-11:59 pm

1 stop10h 16m

$510

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

jue. 11/27

6:45 am-7:38 pm

1 stop11h 53m

Panama City Tocumen Intl

jue. 12/4

8:55 am-8:11 pm

1 stop12h 16m

$510

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

jue. 2/5

6:15 am-7:38 pm

1 stop12h 23m

Panama City Tocumen Intl

dom. 2/8

8:55 am-4:09 pm

1 stop8h 14m

$510

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/11

Showing 1-10 of 42 results
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Best time to book a flight from Mississippi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Panama City
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Mississippi?

    Most people fly into Panama City Tocumen Intl (PTY) if they book a flight to Panama City from Mississippi. Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • How long is the flight from Mississippi to Panama City?

    There are many flights that can get you from Mississippi to Panama City in 7h 08m. Fly via United Airlines, American Airlines, or Delta to get the fastest option. Mississippi and Panama City are separated by a distance of 1598 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mississippi to Panama City one-way?

    The cheapest airlines for a one-way flight from Mississippi to Panama City are Delta ($232), American Airlines ($232), and United Airlines ($246).

  • What are the most popular routes from Mississippi to Panama City?

    While some choose either Memphis - Panama City Tocumen Intl or Gulfport Biloxi Regional - Panama City Tocumen Intl, Jackson-Evers Intl - Panama City Tocumen Intl is the most popular route from Mississippi to Panama City.

  • Can I find deals for flights from Mississippi to Panama City that include hotel bookings?

    Yes. In addition to deals on Mississippi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Panama City.

  • Can I find deals for business class flights from Mississippi to Panama City?

    Yes. Cheapflights offers flight deals from Mississippi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Mississippi to Panama City

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Top airline flying from Mississippi to Panama City

Discover the top airline that operate flights from Mississippi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$445Average$609FlexibilityNo cancel feeOn-time69%

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