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Panama City

$212+ Cheap flights from Mississippi to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — PTY
מרץ 1 — מרץ 81
א' 3/1
א' 3/8
1 adult, Economy
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Cheap flight deals from Mississippi to Panama City

Cheapest flights from Mississippi to Panama City
Explore the most affordable flight options available from Mississippi to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on ינואר 30, 2026.

This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ו' 4/244:55 pm
MOB
-
PTY
1 stop21h 19m
United Airlines
א' 5/37:55 am
PTY
-
MOB
1 stop14h 04m
United Airlines
Deal found 1/29$505
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ד' 5/209:00 am
MEM
-
PTY
1 stop9h 37m
United Airlines
ד' 5/2710:00 am
PTY
-
MEM
1 stop8h 08m
United Airlines
Deal found 1/29$511
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ד' 5/205:47 am
MEM
-
PTY
1 stop6h 49m
American Airlines
ד' 5/271:10 pm
PTY
-
MEM
2 stops10h 42m
American Airlines
Deal found 1/29$515
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ב' 2/239:00 am
MOB
-
PTY
1 stop9h 38m
United Airlines
ו' 2/278:55 am
PTY
-
MOB
1 stop10h 18m
United Airlines
Deal found 1/26$517
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ב' 3/237:00 am
MOB
-
PTY
1 stop6h 45m
United Airlines
ו' 3/277:55 am
PTY
-
MOB
1 stop28h 09m
United Airlines
Deal found 1/29$525
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ו' 4/246:33 pm
MOB
-
PTY
2 stops18h 03m
American Airlines
א' 5/31:49 pm
PTY
-
MOB
2 stops20h 25m
American Airlines
Deal found 1/27$526
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ב' 5/186:15 am
MEM
-
PTY
1 stop12h 22m
United Airlines
א' 5/247:55 am
PTY
-
MEM
1 stop10h 13m
United Airlines
Deal found 1/29$531
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ב' 3/236:45 pm
MOB
-
PTY
2 stops19h 35m
American Airlines
ו' 3/273:10 pm
PTY
-
MOB
2 stops19h 11m
American Airlines
Deal found 1/29$536
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ב' 5/183:44 pm
MEM
-
PTY
2 stops20h 52m
American Airlines
א' 5/241:10 pm
PTY
-
MEM
1 stop10h 49m
American Airlines
Deal found 1/29$540
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ב' 2/231:58 pm
GPT
-
PTY
1 stop28h 40m
United Airlines
ו' 2/274:41 pm
PTY
-
GPT
1 stop27h 53m
United Airlines
Deal found 1/28$553
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ש' 3/147:23 pm
MEM
-
PTY
2 stops18h 57m
American Airlines
ג' 3/243:10 pm
PTY
-
MEM
1 stop8h 42m
American Airlines
Deal found 1/27$555
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ד' 2/257:00 am
JAN
-
PTY
1 stop11h 38m
United Airlines
ש' 2/284:41 pm
PTY
-
JAN
1 stop24h 20m
United Airlines
Deal found 1/26$565

Find flight deals from Mississippi to Panama City

Keep the following information in mind while searching for Mississippi to Panama City flight deals. Data was last updated ינואר 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$505
(United Airlines)

One-way from

$212
(Avianca Connect)
Provider with most accurate pricing for Jackson-Evers Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Panama City Tocumen Intl flights.
Search Deals
From Mississippi to Panama City Tocumen Intl
Search Deals
One-way flight from Mississippi to Panama City Tocumen Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated ינואר 30, 2026.
Use the filters below to find and compare flights from Mississippi to Panama City that are best for you.

Fly from

Mississippi

Fly to

Panama City

Route

Depart

Return

Price

MobilePanama City

MOB - PTY

MOBPTY

Mobile

ו' 4/24

4:55 pm-4:12 pm

1 stop23h 17m

Panama City Tocumen Intl

א' 5/3

7:55 am-9:59 pm

1 stop14h 04m

$505

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

ד' 5/20

5:47 am-12:36 pm

1 stop6h 49m

Panama City Tocumen Intl

ד' 5/27

1:10 pm-11:52 pm

2 stops10h 42m

$515

MobilePanama City

MOB - PTY

MOBPTY

Mobile

ב' 2/23

9:00 am-7:38 pm

1 stop9h 38m

Panama City Tocumen Intl

ו' 2/27

8:55 am-6:13 pm

1 stop10h 18m

$517

MobilePanama City

MOB - PTY

MOBPTY

Mobile

ב' 3/23

7:00 am-1:45 pm

1 stop6h 45m

Panama City Tocumen Intl

ו' 3/27

7:55 am-12:04 pm

1 stop28h 09m

$525

MobilePanama City

MOB - PTY

MOBPTY

Mobile

ו' 4/24

6:33 pm-12:36 pm

2 stops18h 03m

Panama City Tocumen Intl

א' 5/3

1:49 pm-10:14 am

2 stops20h 25m

$526

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

ב' 5/18

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

א' 5/24

7:55 am-6:08 pm

1 stop10h 13m

$531

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

ב' 5/18

3:44 pm-12:36 pm

2 stops20h 52m

Panama City Tocumen Intl

א' 5/24

1:10 pm-11:59 pm

1 stop10h 49m

$540

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

ב' 2/23

4:55 pm-5:07 pm

1 stop23h 12m

Panama City Tocumen Intl

ו' 2/27

4:41 pm-1:20 pm

1 stop21h 39m

$553

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

ש' 3/14

7:23 pm-2:20 pm

2 stops18h 57m

Panama City Tocumen Intl

ג' 3/24

3:10 pm-11:52 pm

1 stop8h 42m

$555

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

ד' 2/25

7:00 am-7:38 pm

1 stop11h 38m

Panama City Tocumen Intl

ש' 2/28

4:41 pm-4:01 pm

1 stop24h 20m

$565

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 34 results
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Best time to book a flight from Mississippi to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Panama City
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Mississippi?

    Most people fly into Panama City Tocumen Intl (PTY) if they book a flight to Panama City from Mississippi. Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • How long is the flight from Mississippi to Panama City?

    There are many flights that can get you from Mississippi to Panama City in 6h 49m. Fly via United Airlines, American Airlines, or JetBlue to get the fastest option. Mississippi and Panama City are separated by a distance of 1914 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Mississippi to Panama City?

    While some choose either Mobile - Panama City Tocumen Intl or Jackson-Evers Intl - Panama City Tocumen Intl, Memphis - Panama City Tocumen Intl is the most popular route from Mississippi to Panama City.

  • Can I find deals for flights from Mississippi to Panama City that include hotel bookings?

    Yes. In addition to deals on Mississippi to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Panama City.

  • Can I find deals for business class flights from Mississippi to Panama City?

    Yes. Cheapflights offers flight deals from Mississippi to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Mississippi to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Mississippi to Panama City

Discover the top airline that operate flights from Mississippi to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated ינואר 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$445Average$609FlexibilityNo cancel feeOn-time69%

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