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Panama City

$198+ Cheap flights from Iowa to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PTY
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
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Cheap flight deals from Iowa to Panama City

Keep the following information in mind while searching for Iowa to Panama City flight deals. Data was last updated septiembre 15, 2025.

Round-trip from

$461
(United Airlines)

One-way from

$198
(Delta)

Popular in

June

Cheapest in

December

Average price

$441
From Iowa to Panama City Tocumen Intl
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One-way flight from Iowa to Panama City Tocumen Intl
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Highest demand for flights based on searches. 15% potential increase in price ($108 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($45 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Iowa to Panama City

Cheapest flights from Iowa to Panama City
Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/306:05 amDSM - PTY
1 stop7h 40mUnited Airlines
jue. 11/68:55 amPTY - DSM
1 stop14h 25mUnited Airlines
Deal found 9/15$461
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/126:15 amDSM - PTY
1 stop12h 22mUnited Airlines
sáb. 10/183:30 pmPTY - DSM
2 stops19h 02mUnited Airlines
Deal found 9/15$466
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/113:05 pmDSM - PTY
1 stop23h 09mUnited Airlines
mar. 10/2110:00 amPTY - DSM
1 stop12h 28mUnited Airlines
Deal found 9/13$470
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/115:15 pmDSM - PTY
1 stop19h 41mDelta
mié. 10/222:21 pmPTY - DSM
2 stops18h 59mDelta
Deal found 9/13$475
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/113:05 pmDSM - PTY
1 stop23h 09mUnited Airlines
lun. 10/203:30 pmPTY - DSM
1 stop22h 43mUnited Airlines
Deal found 9/13$479
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/105:56 pmDSM - PTY
2 stops43h 00mDelta
mié. 10/222:21 pmPTY - DSM
1 stop8h 09mDelta
Deal found 9/13$481
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/166:15 amDSM - PTY
1 stop12h 22mUnited Airlines
dom. 10/193:30 pmPTY - DSM
2 stops22h 53mUnited Airlines
Deal found 9/13$508
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/305:42 pmDSM - PTY
2 stops20h 21mAmerican Airlines
jue. 11/62:49 pmPTY - DSM
2 stops20h 51mAmerican Airlines
Deal found 9/15$509
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/113:05 pmDSM - PTY
1 stop23h 09mUnited Airlines
jue. 10/2310:00 amPTY - DSM
1 stop12h 22mUnited Airlines
Deal found 9/13$512
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/1211:06 amDSM - PTY
2 stops25h 50mDelta
jue. 10/232:21 pmPTY - DSM
2 stops18h 59mDelta
Deal found 9/13$513
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/276:00 amOMA - PTY
1 stop7h 45mUnited Airlines
mar. 11/48:55 amPTY - OMA
1 stop10h 54mUnited Airlines
Deal found 9/15$541
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/296:00 amOMA - PTY
1 stop7h 45mUnited Airlines
mié. 11/54:41 pmPTY - OMA
1 stop30h 26mUnited Airlines
Deal found 9/14$551

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.

Fly from

Iowa

Fly to

Panama City

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

mié. 10/15

6:39 pm-12:56 pm

1 stop18h 17m

Panama City Tocumen Intl

mié. 10/22

2:21 pm-10:30 pm

1 stop8h 09m

$461

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

jue. 10/30

6:05 am-1:45 pm

1 stop7h 40m

Panama City Tocumen Intl

jue. 11/6

8:55 am-10:20 pm

1 stop14h 25m

$461

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

dom. 10/12

6:15 am-2:14 pm

1 stop7h 59m

Panama City Tocumen Intl

mar. 10/21

10:00 am-10:28 pm

1 stop12h 28m

$461

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

jue. 1/1

2:07 pm-1:53 pm

2 stops22h 46m

Panama City Tocumen Intl

mié. 4/1

3:50 pm-12:31 pm

2 stops20h 41m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

mié. 10/15

6:39 pm-12:56 pm

1 stop18h 17m

Panama City Tocumen Intl

jue. 10/23

2:21 pm-9:20 am

2 stops18h 59m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

dom. 2/8

8:10 am-5:07 pm

1 stop7h 57m

Panama City Tocumen Intl

sáb. 2/14

11:55 pm-9:51 pm

2 stops22h 56m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

sáb. 10/11

8:00 am-6:37 pm

2 stops10h 37m

Panama City Tocumen Intl

mar. 10/21

3:30 pm-10:32 am

2 stops19h 02m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

dom. 10/12

6:15 am-2:14 pm

1 stop7h 59m

Panama City Tocumen Intl

vie. 10/17

3:30 pm-12:11 pm

2 stops20h 41m

$466

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

dom. 2/22

5:15 pm-2:45 pm

2 stops20h 30m

Panama City Tocumen Intl

jue. 2/26

4:41 pm-12:35 pm

2 stops20h 54m

$526

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

mié. 3/11

6:00 am-5:49 pm

1 stop11h 49m

Panama City Tocumen Intl

lun. 3/16

3:00 pm-11:59 pm

1 stop32h 59m

$531

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 29 results
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Best time to book a flight from Iowa to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama City

What is the cheapest month to book a flight from Iowa to Panama City?

Currently, October is the cheapest month in which you can book a flight from Iowa to Panama City (average of $478). Flying from Iowa to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to PTY?

Find hourly flight availability from Iowa to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

When flying from Iowa to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Iowa?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Iowa to Panama City.

  • How long is the flight from Iowa to Panama City?

    Departing from Iowa to Panama City will take you 7h 40m. Airlines will cover a distance of 2405 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Iowa to Panama City one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $198. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Iowa to Panama City for a low price.

  • What are the most popular routes from Iowa to Panama City?

    The most popular flight routes from Iowa to Panama City are Des Moines - Panama City Tocumen Intl, Omaha Eppley Airfield - Panama City Tocumen Intl and Cedar Rapids - Panama City Tocumen Intl.

  • Can I find deals for flights from Iowa to Panama City that include hotel bookings?

    Yes. In addition to deals on Iowa to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama City.

  • Can I find deals for business class flights from Iowa to Panama City?

    Yes. Cheapflights offers flight deals from Iowa to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Iowa to Panama City (average of $478). Flying from Iowa to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Panama City

Discover the top 3 airlines that operate flights from Iowa to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$411Average$484FlexibilityNo cancel feeOn-time69%
DeltaCheapest$441Average$632FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$445Average$544FlexibilityNo cancel feeOn-time71%

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