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Panama City

$188+ Cheap flights from Iowa to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PTY
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Iowa to Panama City

Keep the following information in mind while searching for Iowa to Panama City flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$435
(Kissandfly.com)

One-way from

$188
(Delta)

Popular in

March

Cheapest in

August

Average price

$556
Provider with most accurate pricing for Des Moines-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Panama City Tocumen Intl flights.
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From Iowa to Panama City Tocumen Intl
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One-way flight from Iowa to Panama City Tocumen Intl
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Highest demand for flights based on searches. 18% potential increase in price ($116 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($31 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Iowa to Panama City

Cheapest flights from Iowa to Panama City
Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Kissandfly.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/135:52 pmDSM - PTY
2 stops25h 10mKLM
Fri 6/202:23 pmPTY - DSM
2 stops19h 15mKLM
Deal found 4/30$435
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/28:00 amDSM - PTY
1 stop8h 12mUnited Airlines
Mon 5/57:55 amPTY - DSM
1 stop14h 50mUnited Airlines
Deal found 4/30$441
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/136:07 amDSM - PTY
2 stops13h 23mDelta
Fri 6/202:23 pmPTY - DSM
1 stop8h 40mDelta
Deal found 4/30$483
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/123:40 pmDSM - PTY
2 stops22h 45mAmerican Airlines
Thu 6/191:50 pmPTY - DSM
2 stops19h 17mAmerican Airlines
Deal found 4/30$484
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:35 amOMA - PTY
1 stop7h 12mDelta
Tue 11/43:12 pmPTY - OMA
1 stop9h 44mDelta
Deal found 4/30$501
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:15 pmOMA - PTY
2 stops20h 30mUnited Airlines
Tue 11/44:40 pmPTY - OMA
3 stops20h 23mUnited Airlines
Deal found 4/30$506
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:45 amCID - PTY
1 stop7h 02mDelta
Wed 10/222:12 pmPTY - CID
1 stop7h 39mDelta
Deal found 5/1$521
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1712:39 pmCID - PTY
2 stops23h 46mAmerican Airlines
Wed 10/221:50 pmPTY - CID
2 stops21h 05mAmerican Airlines
Deal found 5/1$526
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/186:04 pmOMA - PTY
2 stops18h 56mAmerican Airlines
Sun 6/221:50 pmPTY - OMA
2 stops18h 53mAmerican Airlines
Deal found 5/1$602
This Mytrip deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/156:32 pmDSM - PTY
3 stops26h 38mMultiple Airlines
Sun 6/227:28 amPTY - DSM
2 stops30h 27mMultiple Airlines
Deal found 5/1$678
This Avianca deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:00 amDSM - PTY
2 stops24h 40mAvianca
Tue 12/305:25 pmPTY - DSM
2 stops29h 11mAvianca
Deal found 4/30$2,451
This Orbitz deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/76:35 amOMA - PTY
3 stops26h 50mMultiple Airlines
Sat 12/138:05 pmPTY - OMA
3 stops28h 46mMultiple Airlines
Deal found 5/1$12,129

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Iowa to Panama City that are best for you.

Fly from

Iowa

Fly to

Panama City

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Fri 6/13

5:52 pm-7:02 pm

2 stops25h 10m

Panama City Tocumen Intl

Fri 6/20

2:23 pm-9:38 am

2 stops19h 15m

$435

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 5/24

6:30 am-7:53 pm

2 stops13h 23m

Panama City Tocumen Intl

Sat 5/31

8:00 am-5:50 pm

1 stop9h 50m

$446

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 5/24

3:01 pm-4:12 pm

1 stop25h 11m

Panama City Tocumen Intl

Sat 5/31

10:00 am-10:32 pm

1 stop12h 32m

$450

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Thu 6/12

3:40 pm-2:25 pm

2 stops22h 45m

Panama City Tocumen Intl

Thu 6/19

1:50 pm-9:07 am

2 stops19h 17m

$484

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Mon 10/27

5:35 am-12:47 pm

1 stop7h 12m

Panama City Tocumen Intl

Tue 11/4

3:12 pm-11:56 pm

1 stop9h 44m

$501

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Mon 10/27

5:15 pm-1:45 pm

2 stops20h 30m

Panama City Tocumen Intl

Tue 11/4

4:40 pm-12:03 pm

3 stops20h 23m

$506

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Fri 10/17

5:45 am-12:47 pm

1 stop7h 02m

Panama City Tocumen Intl

Wed 10/22

2:12 pm-9:51 pm

1 stop7h 39m

$521

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Fri 10/17

12:39 pm-12:25 pm

2 stops23h 46m

Panama City Tocumen Intl

Wed 10/22

1:50 pm-10:55 am

2 stops21h 05m

$526

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Wed 6/18

6:04 pm-1:00 pm

2 stops18h 56m

Panama City Tocumen Intl

Sun 6/22

1:50 pm-8:43 am

2 stops18h 53m

$602

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 6/15

6:32 pm-9:10 pm

3 stops26h 38m

Panama City Tocumen Intl

Sun 6/22

7:28 am-1:55 pm

2 stops30h 27m

$678

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 15 results
1
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Best time to book a flight from Iowa to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama City

What is the cheapest month to book a flight from Iowa to Panama City?

Currently, October is the cheapest month in which you can book a flight from Iowa to Panama City (average of $478). Flying from Iowa to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to PTY?

Find hourly flight availability from Iowa to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from Iowa to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated May 1, 2025.
Read through reviews of airlines operating flights from Iowa to Panama City, such as Delta, KLM and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
KLM
7.8
Good
1,334 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Iowa?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Iowa to Panama City.

  • What are the cheapest airlines to fly from Iowa to Panama City one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $188. However, be on the lookout for offers from United Airlines and American Airlines, as they are both options that can get you from Iowa to Panama City for a low price.

  • What are the most popular routes from Iowa to Panama City?

    The most popular flight routes from Iowa to Panama City are Omaha Eppley Airfield - Panama City Tocumen Intl, Des Moines - Panama City Tocumen Intl and Cedar Rapids - Panama City Tocumen Intl.

  • Can I find deals for flights from Iowa to Panama City that include hotel bookings?

    Yes. In addition to deals on Iowa to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama City.

  • Can I find deals for business class flights from Iowa to Panama City?

    Yes. Cheapflights offers flight deals from Iowa to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Iowa to Panama City (average of $478). Flying from Iowa to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Panama City

Discover the top 3 airlines that operate flights from Iowa to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$349Average$623FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$349Average$518FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$354Average$544FlexibilityNo cancel feeOn-time71%

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