How long is the flight from Iowa to Panama City?

Departing from Iowa to Panama City will take you 7h 10m. Airlines will cover a distance of 2405 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the most popular routes from Iowa to Panama City?

The most popular flight routes from Iowa to Panama City are Des Moines - Panama City Tocumen Intl, Omaha Eppley Airfield - Panama City Tocumen Intl and Cedar Rapids - Panama City Tocumen Intl.

What airport do you fly into for flights to Panama City from Iowa?

Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Iowa to Panama City.

Can I find deals for flights from Iowa to Panama City that include hotel bookings?

Yes. In addition to deals on Iowa to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Iowa to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama City.

Can I find deals for business class flights from Iowa to Panama City?

Yes. Cheapflights offers flight deals from Iowa to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$348+ Cheap Flights from Iowa to Panama City

Q: How much does it cost to fly round-trip from Iowa to Panama City?

Airfare is below average for this route at the moment. Iowa to Panama City flights typically cost between $509 and $588 in May. The cheapest round-trip price found within the last 3 days was $462 on Delta (May 2-May 5).

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Find flight deals from Iowa to Panama City

Cheapest flights from Iowa to Panama City
Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

Sat 12/138:15 amDSM - PTY

1 stop10h 23mUnited Airlines

Fri 12/268:55 amPTY - DSM

1 stop14h 35mUnited Airlines

Deal found 11/2

$462

Tue 12/163:18 pmDSM - PTY

2 stops23h 24mAmerican Airlines

Tue 12/234:55 pmPTY - DSM

2 stops21h 26mAmerican Airlines

Deal found 11/1

$467

Mon 11/246:05 amDSM - PTY

1 stop7h 40mUnited Airlines

Thu 11/274:41 pmPTY - DSM

1 stop30h 39mUnited Airlines

Deal found 11/1

$471

Tue 12/162:53 pmDSM - PTY

1 stop27h 45mUnited Airlines

Tue 12/234:41 pmPTY - DSM

2 stops19h 09mUnited Airlines

Deal found 11/1

$475

Tue 11/185:10 amOMA - PTY

1 stop8h 02mDelta

Thu 12/43:46 pmPTY - OMA

1 stop9h 30mDelta

Deal found 11/1

$582

Tue 11/189:34 amOMA - PTY

2 stops27h 15mAmerican Airlines

Thu 12/42:50 pmPTY - OMA

1 stop10h 06mAmerican Airlines

Deal found 11/1

$586

Mon 12/225:15 pmOMA - PTY

2 stops20h 30mUnited Airlines

Mon 12/2911:35 amPTY - OMA

1 stop11h 47mUnited Airlines

Deal found 11/1

$636

Mon 12/227:31 pmOMA - PTY

2 stops19h 23mAmerican Airlines

Mon 12/292:53 pmPTY - OMA

2 stops20h 49mAmerican Airlines

Deal found 11/1

$736

Fri 12/265:38 pmOMA - PTY

2 stops21h 16mAmerican Airlines

Sun 1/44:55 pmPTY - OMA

2 stops21h 43mAmerican Airlines

Deal found 11/2

$1,175

Fri 12/261:58 pmOMA - PTY

2 stops22h 55mAmerican Airlines

Sat 1/34:55 pmPTY - OMA

2 stops21h 43mAmerican Airlines

Deal found 10/30

$1,342

Best flights from Iowa to Panama City
Discover carefully curated flight deals from Iowa to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 3, 2025.

Fri 11/286:05 amDSM - PTY

1 stop12h 33mUnited Airlines

Fri 12/58:55 amPTY - DSM

1 stop14h 34mUnited Airlines

Deal found 10/31

$462

Sat 5/25:45 amDSM - PTY

1 stop7h 10mDelta

Tue 5/52:20 pmPTY - DSM

1 stop8h 04mDelta

Deal found 10/31

$462

Thu 1/12:07 pmDSM - PTY

2 stops22h 46mAmerican Airlines

Wed 4/11:50 pmPTY - DSM

1 stop8h 35mAmerican Airlines

Deal found 11/1

$466

Sat 12/138:15 amDSM - PTY

1 stop10h 23mUnited Airlines

Fri 12/268:55 amPTY - DSM

1 stop14h 35mUnited Airlines

Deal found 11/2

$462

Thu 2/268:08 amDSM - PTY

1 stop7h 59mUnited Airlines

Sat 3/78:55 amPTY - DSM

1 stop14h 41mUnited Airlines

Deal found 11/1

$462

Sat 5/25:45 amCID - PTY

1 stop7h 10mDelta

Wed 5/62:20 pmPTY - CID

2 stops25h 24mDelta

Deal found 10/31

$546

Tue 2/248:08 amDSM - PTY

1 stop10h 30mUnited Airlines

Fri 3/611:35 amPTY - DSM

1 stop12h 01mUnited Airlines

Deal found 10/31

$462

Tue 11/183:38 pmOMA - PTY

2 stops21h 11mAmerican Airlines

Thu 12/42:50 pmPTY - OMA

2 stops18h 47mAmerican Airlines

Deal found 11/1

$586

Mon 1/196:48 pmDSM - PTY

2 stops21h 19mUnited Airlines

Fri 1/234:41 pmPTY - DSM

2 stops19h 14mUnited Airlines

Deal found 11/2

$466

Tue 11/185:10 amOMA - PTY

1 stop8h 02mDelta

Thu 12/43:46 pmPTY - OMA

1 stop9h 30mDelta

Deal found 11/1

$582

Tue 12/163:17 pmDSM - PTY

2 stops22h 28mUnited Airlines

Tue 12/2311:55 pmPTY - DSM

2 stops20h 34mUnited Airlines

Deal found 11/1

$466

Sat 5/24:43 pmLSE - PTY

2 stops19h 32mAmerican Airlines

Wed 5/61:55 pmPTY - LSE

2 stops50h 03mAmerican Airlines

Deal found 10/31

$671

Wed 1/148:15 amOMA - PTY

1 stop10h 23mUnited Airlines

Wed 1/2111:35 amPTY - OMA

1 stop8h 19mUnited Airlines

Deal found 10/30

$522

Mon 12/225:15 pmOMA - PTY

2 stops20h 30mUnited Airlines

Mon 12/2911:35 amPTY - OMA

1 stop11h 47mUnited Airlines

Deal found 11/1

$636

Last-minute flights from Iowa to Panama City
Discover last-minute flight deals from Iowa to Panama City. Data last updated November 3, 2025 and is based on user searches.

Tue 11/185:10 amOMA - PTY

1 stop8h 02mDelta

Thu 12/43:46 pmPTY - OMA

1 stop9h 30mDelta

Deal found 11/1

$582

Tue 11/189:34 amOMA - PTY

2 stops27h 15mAmerican Airlines

Thu 12/42:50 pmPTY - OMA

1 stop10h 06mAmerican Airlines

Deal found 11/1

$586

Sat 11/222:52 pmDSM - PTY

1 stop27h 46mUnited Airlines

Fri 11/288:55 amPTY - DSM

1 stop14h 25mUnited Airlines

Deal found 11/2

$615

Mon 11/246:05 amDSM - PTY

1 stop12h 33mUnited Airlines

Thu 11/274:41 pmPTY - DSM

2 stops22h 38mUnited Airlines

Deal found 11/1

$466

Mon 11/2411:30 amDSM - PTY

2 stops25h 13mAmerican Airlines

Thu 11/272:43 pmPTY - DSM

2 stops20h 57mAmerican Airlines

Deal found 11/2

$516

Fri 11/286:05 amDSM - PTY

1 stop12h 33mUnited Airlines

Fri 12/58:55 amPTY - DSM

1 stop14h 34mUnited Airlines

Deal found 10/31

$462

One-way flights from Iowa to Panama City
Search for one-way flight options from Iowa to Panama City. Find affordable one-way fares based on user searches. Data last updated November 3, 2025.

Fri 3/136:20 pmDSM - PTY

2 stops17h 50mAmerican Airlines

Deal found 11/1

$348

Sun 12/77:34 amOMA - PTY

1 stop34h 15mUnited Airlines

Deal found 10/31

$443

Fri 3/133:00 pmDSM - PTY

1 stop22h 45mUnited Airlines

Deal found 10/31

$535

Tue 12/163:17 pmDSM - PTY

2 stops27h 21mUnited Airlines

Deal found 11/1

$566

Tue 12/165:34 amDSM - PTY

1 stop7h 47mDelta

Deal found 11/1

$587

Sun 12/76:02 pmOMA - PTY

2 stops20h 40mAmerican Airlines

Deal found 11/2

$649

Cheap flight deals from Iowa to Panama City

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$462 (United Airlines)
One-way from	$348 (American Airlines)
Popular in	June
Cheapest in	September
Average price	$571

Provider with most accurate pricing for Des Moines-Panama City Tocumen Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Panama City Tocumen Intl flights.

Search Deals

From Iowa to Panama City Tocumen Intl

Search Deals

One-way flight from Iowa to Panama City Tocumen Intl

Search Deals

Highest demand for flights based on searches. 13% potential increase in price ($94 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 7% potential price decrease ($43 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in November 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Fri 11/28

6:05 am-7:38 pm

1 stop12h 33m

Panama City Tocumen Intl

Fri 12/5

8:55 am-10:29 pm

1 stop14h 34m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 5/2

5:45 am-12:55 pm

1 stop7h 10m

Panama City Tocumen Intl

Tue 5/5

2:20 pm-10:24 pm

1 stop8h 04m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 12/13

8:15 am-7:38 pm

1 stop10h 23m

Panama City Tocumen Intl

Fri 12/26

8:55 am-10:30 pm

1 stop14h 35m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Thu 2/26

8:08 am-5:07 pm

1 stop7h 59m

Panama City Tocumen Intl

Sat 3/7

8:55 am-10:36 pm

1 stop14h 41m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 2/24

8:08 am-7:38 pm

1 stop10h 30m

Panama City Tocumen Intl

Fri 3/6

11:35 am-10:36 pm

1 stop12h 01m

$462

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Thu 1/1

2:07 pm-1:53 pm

2 stops22h 46m

Panama City Tocumen Intl

Wed 4/1

1:50 pm-10:25 pm

1 stop8h 35m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Mon 1/19

6:48 pm-5:07 pm

2 stops21h 19m

Panama City Tocumen Intl

Fri 1/23

4:41 pm-10:55 am

2 stops19h 14m

$466

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 12/16

3:17 pm-2:45 pm

2 stops22h 28m

Panama City Tocumen Intl

Tue 12/23

11:55 pm-7:29 pm

2 stops20h 34m

$466

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Wed 1/14

8:15 am-7:38 pm

1 stop10h 23m

Panama City Tocumen Intl

Wed 1/21

11:35 am-6:54 pm

1 stop8h 19m

$522

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Sat 5/2

5:45 am-12:55 pm

1 stop7h 10m

Panama City Tocumen Intl

Wed 5/6

2:20 pm-3:44 pm

2 stops25h 24m

$546

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/31

Showing 1-10 of 20 results

Best time to book a flight from Iowa to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Iowa with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama City

What is the cheapest month to book a flight from Iowa to Panama City?

Currently, December is the cheapest month in which you can book a flight from Iowa to Panama City (average of $401). Flying from Iowa to Panama City in March is currently the most expensive (average of $604). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to PTY?

When flying from Iowa to Panama City, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 30% versus a flight in the morning.

How much does it cost to fly round-trip from Iowa to Panama City?

Related info for your journey

What airport do you fly into for flights to Panama City from Iowa?
Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Iowa to Panama City.
How long is the flight from Iowa to Panama City?
Departing from Iowa to Panama City will take you 7h 10m. Airlines will cover a distance of 2405 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the most popular routes from Iowa to Panama City?
The most popular flight routes from Iowa to Panama City are Des Moines - Panama City Tocumen Intl, Omaha Eppley Airfield - Panama City Tocumen Intl and Cedar Rapids - Panama City Tocumen Intl.
Can I find deals for flights from Iowa to Panama City that include hotel bookings?
Yes. In addition to deals on Iowa to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Iowa to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama City.
Can I find deals for business class flights from Iowa to Panama City?
Yes. Cheapflights offers flight deals from Iowa to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Iowa to Panama City?
Currently, December is the cheapest month in which you can book a flight from Iowa to Panama City (average of $401). Flying from Iowa to Panama City in March is currently the most expensive (average of $604). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Iowa to Panama City

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$414	Average$489	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$441	Average$612	FlexibilityNo cancel fee	On-timeN/A

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$348+ Cheap flights from Iowa to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/13. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Iowa to Panama City with Cheapflights

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Find flight deals from Iowa to Panama City

Cheapest flights from Iowa to Panama CityExplore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

Cheap flight deals from Iowa to Panama City

Keep the following information in mind while searching for Iowa to Panama City flight deals. Data was last updated November 3, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Iowa to Panama City that are best for you.

Best time to book a flight from Iowa to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Iowa with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama City

What is the cheapest month to book a flight from Iowa to Panama City?

What is the cheapest time of day to fly from IA to PTY?

Find hourly flight availability from Iowa to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

How much does it cost to fly round-trip from Iowa to Panama City?

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Panama City from Iowa?

How long is the flight from Iowa to Panama City?

What are the most popular routes from Iowa to Panama City?

Can I find deals for flights from Iowa to Panama City that include hotel bookings?

How can I find direct flights from Iowa to Panama City?

Can I find deals for business class flights from Iowa to Panama City?

What is the cheapest month to book a flight from Iowa to Panama City?

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Alternative routes for Iowa to Panama City

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Top 2 airlines flying from Iowa to Panama City

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Cheapest flights from Iowa to Panama City
Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.