How popular is this Colorado to Panama City flight route?

Within the past month, 38 users have taken a look at flights from Colorado to Panama City Tocumen Intl.

How long is the flight from Colorado to Panama City?

A quick flight from Colorado to Panama City can take about 5h 45m. Copa Airlines provides one of the quickest options available for as low as $535. Colorado and Panama City are separated by a distance of 2634 mi. Most flights are nonstop.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the cheapest flights from Colorado to Panama City?

The cheapest flight price from Colorado to Panama City is $154. On average you can expect to pay $1,025. The most popular route, (Denver Intl - Panama City Tocumen Intl), can usually be booked for $535.

What are the most popular airlines that fly from Colorado to Panama City?

Consider Copa Airlines, United Airlines or American Airlines when booking your flight. These represent the most popular airlines when flying from Colorado to Panama City.

What airport do you fly into for flights to Panama City from Colorado?

If you book a flight to Panama City from Colorado, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City.

Can I find deals for flights from Colorado to Panama City that include hotel bookings?

Yes. In addition to deals on Colorado to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Colorado to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Panama City.

Can I find deals for business class flights from Colorado to Panama City?

Yes. Cheapflights offers flight deals from Colorado to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$177+ Flights from Colorado to Panama City

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Find flight deals from Colorado to Panama City

Cheapest flights from Colorado to Panama City
Explore the most affordable flight options available from Colorado to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Sun 11/1612:34 amDEN - PTY

1 stop11h 56mMultiple Airlines

Mon 12/89:33 pmPTY - DEN

1 stop13h 10mMultiple Airlines

Deal found 10/27

$464

Wed 12/311:25 pmDEN - PTY

1 stop14h 30mMultiple Airlines

Mon 12/89:33 pmPTY - DEN

1 stop13h 10mMultiple Airlines

Deal found 10/27

$477

Fri 12/511:25 pmDEN - PTY

1 stop14h 30mMultiple Airlines

Mon 12/89:33 pmPTY - DEN

1 stop13h 10mMultiple Airlines

Deal found 10/27

$492

Sat 12/611:25 pmDEN - PTY

1 stop14h 30mMultiple Airlines

Mon 12/89:33 pmPTY - DEN

1 stop13h 10mMultiple Airlines

Deal found 10/27

$493

Wed 12/311:25 pmDEN - PTY

2 stops39h 30mMultiple Airlines

Tue 12/99:33 pmPTY - DEN

1 stop13h 10mMultiple Airlines

Deal found 10/27

$499

Wed 12/311:25 pmDEN - PTY

2 stops39h 30mMultiple Airlines

Wed 12/101:45 pmPTY - DEN

1 stop22h 27mMultiple Airlines

Deal found 10/27

$500

Thu 12/411:25 pmDEN - PTY

2 stops33h 05mMultiple Airlines

Tue 12/99:33 pmPTY - DEN

1 stop13h 10mMultiple Airlines

Deal found 10/27

$504

Mon 12/16:20 amDEN - PTY

1 stop21h 00mMultiple Airlines

Mon 12/85:50 pmPTY - DEN

2 stops16h 53mMultiple Airlines

Deal found 10/27

$520

Wed 12/312:59 amDEN - PTY

2 stops12h 56mMultiple Airlines

Wed 12/109:33 pmPTY - DEN

1 stop13h 10mMultiple Airlines

Deal found 10/30

$521

Best flights from Colorado to Panama City
Discover carefully curated flight deals from Colorado to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2025.

Thu 3/59:48 pmDEN - PTY

Nonstop5h 45mCopa Airlines

Sun 3/812:56 pmPTY - DEN

Nonstop6h 20mCopa Airlines

Deal found 10/28

$535

Sun 3/18:33 pmDEN - PTY

1 stop18h 34mUnited Airlines

Mon 3/97:55 amPTY - DEN

1 stop15h 15mUnited Airlines

Deal found 10/30

$550

Sat 2/2812:59 amDEN - PTY

1 stop11h 03mDelta

Tue 3/33:27 pmPTY - DEN

1 stop10h 57mDelta

Deal found 10/29

$550

Sat 2/289:38 pmDEN - PTY

Nonstop5h 55mCopa Airlines

Sun 3/812:56 pmPTY - DEN

Nonstop6h 20mCopa Airlines

Deal found 10/30

$535

Tue 2/2410:05 amDEN - PTY

1 stop7h 33mUnited Airlines

Wed 3/48:55 amPTY - DEN

1 stop11h 21mUnited Airlines

Deal found 10/29

$550

Fri 2/2010:19 pmDEN - PTY

Nonstop5h 51mCopa Airlines

Tue 2/2412:56 pmPTY - DEN

Nonstop6h 20mCopa Airlines

Deal found 10/29

$535

Sat 1/179:38 pmDEN - PTY

Nonstop5h 55mCopa Airlines

Wed 1/2812:56 pmPTY - DEN

Nonstop6h 20mCopa Airlines

Deal found 10/28

$548

Mon 1/129:38 pmDEN - PTY

Nonstop5h 55mCopa Airlines

Thu 1/2212:56 pmPTY - DEN

Nonstop6h 20mCopa Airlines

Deal found 10/29

$548

Thu 1/19:38 pmDEN - PTY

Nonstop5h 55mCopa Airlines

Sun 1/1812:56 pmPTY - DEN

Nonstop6h 20mCopa Airlines

Deal found 10/28

$548

Last-minute flights from Colorado to Panama City
Discover last-minute flight deals from Colorado to Panama City. Data last updated October 30, 2025 and is based on user searches.

Thu 11/612:34 amDEN - PTY

1 stop11h 56mMultiple Airlines

Fri 11/79:33 pmPTY - DEN

1 stop13h 00mMultiple Airlines

Deal found 10/28

$605

Sun 11/1612:34 amDEN - PTY

1 stop11h 56mMultiple Airlines

Mon 12/89:33 pmPTY - DEN

1 stop13h 10mMultiple Airlines

Deal found 10/27

$464

Thu 11/206:00 amDEN - PTY

1 stop10h 49mUnited Airlines

Tue 11/253:35 pmPTY - DEN

1 stop19h 03mUnited Airlines

Deal found 10/28

$621

Tue 11/2510:29 pmDEN - PTY

1 stop28h 51mMultiple Airlines

Tue 12/22:55 pmPTY - DEN

2 stops22h 03mMultiple Airlines

Deal found 10/28

$597

Tue 11/2512:53 pmDEN - PTY

1 stop22h 50mAmerican Airlines

Tue 12/22:43 pmPTY - DEN

2 stops20h 47mAmerican Airlines

Deal found 10/28

$608

Thu 11/279:38 pmDEN - PTY

Nonstop5h 55mCopa Airlines

Thu 12/412:56 pmPTY - DEN

Nonstop6h 21mCopa Airlines

Deal found 10/29

$574

Sun 11/3012:50 amDEN - PTY

1 stop11h 22mDelta

Tue 12/93:46 pmPTY - DEN

1 stop19h 43mDelta

Deal found 10/27

$589

Sun 11/3012:17 amDEN - PTY

1 stop11h 26mAmerican Airlines

Fri 12/124:43 pmPTY - DEN

2 stops20h 41mAmerican Airlines

Deal found 10/28

$593

One-way flights from Colorado to Panama City
Search for one-way flight options from Colorado to Panama City. Find affordable one-way fares based on user searches. Data last updated October 30, 2025.

Mon 12/811:25 pmDEN - PTY

3 stops33h 05mMultiple Airlines

Deal found 10/29

$177

Sat 12/611:25 pmDEN - PTY

2 stops36h 35mMultiple Airlines

Deal found 10/29

$197

Wed 12/1011:25 pmDEN - PTY

3 stops33h 05mMultiple Airlines

Deal found 10/29

$199

Mon 1/1211:25 pmDEN - PTY

2 stops33h 05mMultiple Airlines

Deal found 10/28

$200

Thu 12/411:25 pmDEN - PTY

2 stops33h 05mMultiple Airlines

Deal found 10/30

$206

Tue 1/136:38 pmDEN - PTY

3 stops37h 52mMultiple Airlines

Deal found 10/28

$209

Wed 1/288:50 pmDEN - PTY

3 stops39h 10mMultiple Airlines

Deal found 10/27

$218

Tue 12/911:25 pmDEN - PTY

3 stops33h 05mMultiple Airlines

Deal found 10/29

$220

Sun 12/76:00 amDEN - PTY

3 stops30h 00mMultiple Airlines

Deal found 10/29

$225

Mon 11/1712:59 amDEN - PTY

3 stops29h 51mMultiple Airlines

Deal found 10/30

$227

Cheap flight deals from Colorado to Panama City

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$464 (Kiwi.com)
One-way from	$177 (Kiwi.com)
Popular in	December
Cheapest in	August
Average price	$586
Good round-trip deal	$456 or less
Good one-way deal	$174 or less

Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.

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Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.

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From Colorado to Panama City Tocumen Intl

Search Deals

One-way flight from Colorado to Panama City Tocumen Intl

Search Deals

Highest demand for flights based on searches. 4% potential increase in price ($30 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in October 2025

Search Deals

Price to beat on a round-trip flight from Colorado to Panama City Tocumen Intl.

Search Deals

Price to beat on a one-way flight from Colorado to Panama City Tocumen Intl.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Colorado to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 3/5

9:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Sun 3/8

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/28

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sun 3/8

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/20

10:19 pm-6:10 am

Nonstop5h 51m

Panama City Tocumen Intl

Tue 2/24

12:56 pm-5:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 1/17

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Wed 1/28

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 1/12

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Thu 1/22

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 1/1

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sun 1/18

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 3/1

8:33 pm-5:07 pm

1 stop18h 34m

Panama City Tocumen Intl

Mon 3/9

7:55 am-10:10 pm

1 stop15h 15m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/28

12:59 am-2:02 pm

1 stop11h 03m

Panama City Tocumen Intl

Tue 3/3

3:27 pm-12:24 am

1 stop10h 57m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 2/24

10:05 am-7:38 pm

1 stop7h 33m

Panama City Tocumen Intl

Wed 3/4

8:55 am-6:16 pm

1 stop11h 21m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 12/8

11:25 pm-10:30 am

3 stops33h 05m

$177

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 18 results

Best time to book a flight from Colorado to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Colorado with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Panama City

What is the cheapest month to book a flight from Colorado to Panama City?

Currently, March is the cheapest month in which you can book a flight from Colorado to Panama City (average of $354). Flying from Colorado to Panama City in June is currently the most expensive (average of $521). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to PTY?

It’s optimal to fly from Colorado to Panama City in the evening. By choosing this option you can save up to 68% on the cost of your flight, compared to a flight at noon.

Related info for your journey

What airport do you fly into for flights to Panama City from Colorado?
If you book a flight to Panama City from Colorado, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City.
How popular is this Colorado to Panama City flight route?
Within the past month, 38 users have taken a look at flights from Colorado to Panama City Tocumen Intl.
How long is the flight from Colorado to Panama City?
A quick flight from Colorado to Panama City can take about 5h 45m. Copa Airlines provides one of the quickest options available for as low as $535. Colorado and Panama City are separated by a distance of 2634 mi. Most flights are nonstop.
What are the cheapest flights from Colorado to Panama City?
The cheapest flight price from Colorado to Panama City is $154. On average you can expect to pay $1,025. The most popular route, (Denver Intl - Panama City Tocumen Intl), can usually be booked for $535.
Can I find deals for flights from Colorado to Panama City that include hotel bookings?
Yes. In addition to deals on Colorado to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Colorado to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Panama City.
Can I find deals for business class flights from Colorado to Panama City?
Yes. Cheapflights offers flight deals from Colorado to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Colorado to Panama City?
Currently, March is the cheapest month in which you can book a flight from Colorado to Panama City (average of $354). Flying from Colorado to Panama City in June is currently the most expensive (average of $521). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Colorado to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$489	Average$639	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$518	Average$924	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$527	Average$667	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$527	Average$754	FlexibilityNo cancel fee	On-time69%

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$177+ Cheap flights from Colorado to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Colorado to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Colorado to Panama City

Cheapest flights from Colorado to Panama CityExplore the most affordable flight options available from Colorado to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Explore the most affordable flight options available from Colorado to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Cheap flight deals from Colorado to Panama City

Keep the following information in mind while searching for Colorado to Panama City flight deals. Data was last updated October 30, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Colorado to Panama City that are best for you.

Best time to book a flight from Colorado to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Colorado with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Panama City

What is the cheapest month to book a flight from Colorado to Panama City?

What is the cheapest time of day to fly from CO to PTY?

Find hourly flight availability from Colorado to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Related info for your journey

Find useful and relevant information for your journey from Colorado to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Panama City from Colorado?

How popular is this Colorado to Panama City flight route?

How long is the flight from Colorado to Panama City?

What are the cheapest flights from Colorado to Panama City?

Can I find deals for flights from Colorado to Panama City that include hotel bookings?

How can I find direct flights from Colorado to Panama City?

Can I find deals for business class flights from Colorado to Panama City?

What is the cheapest month to book a flight from Colorado to Panama City?

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Alternative routes for Colorado to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Colorado to Panama City

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Cheapest flights from Colorado to Panama City
Explore the most affordable flight options available from Colorado to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.