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Panama City

$191+ Cheap flights from Colorado to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Colorado to Panama City

Keep the following information in mind while searching for Colorado to Panama City flight deals. Data was last updated September 17, 2025.

Round-trip from

$483
(Kiwi.com)

One-way from

$191
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$648

Good round-trip deal

$430 or less

Good one-way deal

$187 or less
From Colorado to Panama City Tocumen Intl
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One-way flight from Colorado to Panama City Tocumen Intl
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Highest demand for flights based on searches. 5% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Colorado to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Colorado to Panama City Tocumen Intl.
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Find flight deals from Colorado to Panama City

Cheapest flights from Colorado to Panama City
Explore the most affordable flight options available from Colorado to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:34 amDEN - PTY
1 stop13h 20mMultiple Airlines
Sun 11/169:33 pmPTY - DEN
1 stop13h 00mMultiple Airlines
Deal found 9/14$483
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/158:21 pmDEN - PTY
2 stops22h 08mMultiple Airlines
Wed 10/229:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 9/15$500
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:00 amDEN - PTY
2 stops13h 37mMultiple Airlines
Fri 10/249:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 9/17$502
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/56:55 pmDEN - PTY
1 stop12h 16mMultiple Airlines
Fri 10/109:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 9/15$513
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:34 amDEN - PTY
1 stop14h 32mMultiple Airlines
Mon 11/38:10 amPTY - DEN
2 stops13h 16mMultiple Airlines
Deal found 9/16$522
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:34 amDEN - PTY
1 stop16h 46mMultiple Airlines
Sun 11/236:34 pmPTY - DEN
1 stop16h 29mMultiple Airlines
Deal found 9/16$523
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:34 amDEN - PTY
1 stop14h 20mMultiple Airlines
Sat 11/89:43 pmPTY - DEN
1 stop12h 50mMultiple Airlines
Deal found 9/17$538
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:36 pmDEN - PTY
Nonstop5h 57mCopa Airlines
Sat 11/1512:56 pmPTY - DEN
Nonstop6h 21mCopa Airlines
Deal found 9/17$548
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:05 amDEN - PTY
1 stop10h 54mDelta
Sun 11/168:05 amPTY - DEN
1 stop9h 08mDelta
Deal found 9/14$552
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:30 amCOS - PTY
1 stop10h 08mUnited Airlines
Thu 11/64:41 pmPTY - COS
2 stops23h 48mUnited Airlines
Deal found 9/15$588
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:00 amCOS - PTY
2 stops11h 38mUnited Airlines
Fri 11/78:55 amPTY - COS
1 stop14h 43mUnited Airlines
Deal found 9/16$623

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Colorado to Panama City that are best for you.

Fly from

Colorado

Fly to

Panama City

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 3/5

9:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Sun 3/8

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 1/17

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Wed 1/28

12:56 pm-5:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/28

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sun 3/8

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 3/5

9:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Mon 3/9

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/20

10:19 pm-6:10 am

Nonstop5h 51m

Panama City Tocumen Intl

Tue 2/24

12:56 pm-5:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 1/17

7:05 am-8:04 pm

1 stop10h 59m

Panama City Tocumen Intl

Tue 1/27

3:27 pm-11:54 pm

1 stop10h 27m

$539

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 1/16

6:05 am-8:04 pm

1 stop11h 59m

Panama City Tocumen Intl

Tue 1/27

3:27 pm-11:54 pm

1 stop10h 27m

$539

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 1/17

6:05 am-8:04 pm

1 stop11h 59m

Panama City Tocumen Intl

Fri 1/30

3:27 pm-11:54 pm

1 stop10h 27m

$539

Colorado SpringsPanama City

COS - PTY

COSPTY

Colorado Springs

Thu 10/30

7:30 am-6:38 pm

1 stop10h 08m

Panama City Tocumen Intl

Thu 11/6

4:41 pm-2:29 pm

2 stops23h 48m

$588

Colorado SpringsPanama City

COS - PTY

COSPTY

Colorado Springs

Fri 10/31

6:00 am-6:38 pm

2 stops11h 38m

Panama City Tocumen Intl

Fri 11/7

8:55 am-9:38 pm

1 stop14h 43m

$623

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 18 results
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Best time to book a flight from Colorado to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Panama City

What is the cheapest month to book a flight from Colorado to Panama City?

Currently, October is the cheapest month in which you can book a flight from Colorado to Panama City (average of $478). Flying from Colorado to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to PTY?

Find hourly flight availability from Colorado to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Colorado to Panama City as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Colorado to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Colorado?

    If you book a flight to Panama City from Colorado, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City.

  • How popular is this Colorado to Panama City flight route?

    Within the past month, 34 users have taken a look at flights from Colorado to Panama City Tocumen Intl.

  • How long is the flight from Colorado to Panama City?

    A quick flight from Colorado to Panama City can take about 5h 45m. Copa Airlines provides one of the quickest options available for as low as $535. Colorado and Panama City are separated by a distance of 2634 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest flights from Colorado to Panama City?

    The cheapest flight price from Colorado to Panama City is $138. On average you can expect to pay $728. The most popular route, (Denver Intl - Panama City Tocumen Intl), can usually be booked for $535.

  • Can I find deals for flights from Colorado to Panama City that include hotel bookings?

    Yes. In addition to deals on Colorado to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Panama City.

  • Can I find deals for business class flights from Colorado to Panama City?

    Yes. Cheapflights offers flight deals from Colorado to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Colorado to Panama City (average of $478). Flying from Colorado to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Colorado to Panama City

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Top 4 airlines flying from Colorado to Panama City

Discover the top 4 airlines that operate flights from Colorado to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$474Average$633FlexibilityNo cancel feeOn-time70%
DeltaCheapest$527Average$825FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$527Average$667FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$672FlexibilityNo cancel feeOn-time69%

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