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$284+ Cheap flights from Colorado to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Aug 17 — Aug 241
Mon 8/17
Mon 8/24
1 adult, Economy
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Cheap flight deals from Colorado to Panama

Cheapest flights from Colorado to Panama
Explore the most affordable flight options available from Colorado to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.

This Orbitz deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:59 pm
DEN
-
PTY
3 stops37h 56m
Multiple Airlines
Thu 9/243:50 pm
PTY
-
DEN
2 stops23h 28m
Multiple Airlines
Deal found 7/13$597
This Expedia deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:55 pm
DEN
-
PTY
3 stops38h 00m
Multiple Airlines
Wed 9/93:50 pm
PTY
-
DEN
2 stops23h 28m
Multiple Airlines
Deal found 7/15$638
This Expedia deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:45 pm
DEN
-
PTY
2 stops33h 45m
Multiple Airlines
Sun 7/263:50 pm
PTY
-
DEN
2 stops32h 09m
Multiple Airlines
Deal found 7/13$641
This Copa Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:43 pm
DEN
-
PTY
Nonstop5h 50m
Copa Airlines
Thu 10/2212:56 pm
PTY
-
DEN
Nonstop6h 15m
Copa Airlines
Deal found 7/14$657
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:40 am
DEN
-
PTY
2 stops22h 09m
Multiple Airlines
Mon 11/29:31 pm
PTY
-
DEN
1 stop14h 17m
Multiple Airlines
Deal found 7/15$662
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:00 am
DEN
-
PTY
1 stop12h 38m
United Airlines
Wed 12/238:55 am
PTY
-
DEN
1 stop11h 21m
United Airlines
Deal found 7/14$663
This Expedia deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/232:09 pm
DEN
-
PTY
2 stops19h 21m
Multiple Airlines
Sun 7/263:50 pm
PTY
-
DEN
2 stops32h 09m
Multiple Airlines
Deal found 7/15$667
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:00 am
DEN
-
PTY
1 stop7h 45m
United Airlines
Sun 11/84:41 pm
PTY
-
DEN
1 stop8h 42m
United Airlines
Deal found 7/13$672
This Copa Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:49 pm
DEN
-
PTY
Nonstop5h 44m
Copa Airlines
Wed 4/1412:56 pm
PTY
-
DEN
Nonstop6h 20m
Copa Airlines
Deal found 7/14$675
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:28 pm
DEN
-
PTY
2 stops21h 24m
American Airlines
Sat 11/72:43 pm
PTY
-
DEN
1 stop10h 18m
American Airlines
Deal found 7/13$676
This Copa Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:50 pm
DEN
-
PTY
Nonstop5h 43m
Copa Airlines
Mon 12/1412:56 pm
PTY
-
DEN
Nonstop6h 14m
Copa Airlines
Deal found 7/15$677
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:14 pm
DEN
-
PTY
2 stops20h 34m
American Airlines
Sun 12/62:50 pm
PTY
-
DEN
2 stops24h 57m
American Airlines
Deal found 7/13$681

Find flight deals from Colorado to Panama

Keep the following information in mind while searching for Colorado to Panama flight deals. Data was last updated July 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$597
(Orbitz)

One-way from

$267
(Travelocity)

Popular in

December

Cheapest in

April

Average price

$667

Good round-trip deal

$586 or less

Good one-way deal

$255 or less
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
Search Deals
From Colorado to Panama
Search Deals
One-way flight from Colorado to Panama
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals
Price to beat on a round-trip flight from Colorado to Panama.
Search Deals
Price to beat on a one-way flight from Colorado to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
Use the filters below to find and compare flights from Colorado to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 10/19

10:43 pm-5:33 am

Nonstop5h 50m

Panama City Tocumen Intl

Thu 10/22

12:56 pm-6:11 pm

Nonstop6h 15m

$657

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 9/8

7:31 pm-2:14 pm

1 stop17h 43m

Panama City Tocumen Intl

Thu 9/24

3:30 pm-6:47 am

1 stop16h 17m

$682

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 9/3

10:43 pm-5:33 am

Nonstop5h 50m

Panama City Tocumen Intl

Sat 9/12

12:56 pm-6:11 pm

Nonstop6h 15m

$685

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 8/13

10:43 pm-5:33 am

Nonstop5h 50m

Panama City Tocumen Intl

Wed 8/19

12:56 pm-6:20 pm

Nonstop6h 24m

$688

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 11/19

5:00 am-2:45 pm

1 stop7h 45m

Panama City Tocumen Intl

Fri 11/27

4:41 pm-11:23 pm

1 stop8h 42m

$692

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 12/1

8:39 pm-2:45 pm

1 stop16h 06m

Panama City Tocumen Intl

Sun 12/6

4:41 pm-11:27 pm

1 stop8h 46m

$692

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 10/17

7:33 pm-2:14 pm

1 stop17h 41m

Panama City Tocumen Intl

Sat 11/7

4:41 pm-9:02 am

1 stop18h 21m

$692

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 12/1

8:39 pm-2:45 pm

1 stop16h 06m

Panama City Tocumen Intl

Sun 12/13

4:41 pm-8:55 am

1 stop18h 14m

$692

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 10/28

7:31 pm-1:45 pm

1 stop17h 14m

Panama City Tocumen Intl

Mon 11/2

8:55 am-10:26 am

3 stops27h 31m

$692

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 12/6

5:00 am-7:38 pm

1 stop12h 38m

Panama City Tocumen Intl

Sat 12/12

8:55 am-5:54 pm

1 stop10h 59m

$692

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/17

Showing 1-10 of 28 resultsSorted by cheapest first
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Best time to book a flight from Colorado to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Panama

What is the cheapest month to book a flight from Colorado to Panama?

Currently, April is the cheapest month in which you can book a flight from Colorado to Panama (average of $597). Flying from Colorado to Panama in December is currently the most expensive (average of $765). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to PA?

Find hourly flight availability from Colorado to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 18, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Colorado to Panama as you normally would.

Weekly flight availability from Colorado to Panama

Explore weekly flight availability from Colorado to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 18, 2026.

The most flights from USCO to PA0 are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

How far ahead should I book a flight from Colorado to Panama?

The price you pay for your flight from Colorado to Panama may vary depending on when you book. For the best chance of a lower fare, look to book 67 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Related info for your journey

Find useful and relevant information for your journey from Colorado to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Colorado to Panama flight route?

    The Colorado to Panama flight path was viewed by 40 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Colorado to Panama?

    Copa Airlines and United Airlines can get you from Colorado to Panama in just under 5h 50m. Your travel time can differ by up to 6h 48m. The distance between Colorado and Panama is about 2634 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Colorado to Panama that include hotel bookings?

    Yes. In addition to deals on Colorado to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Panama.

  • Can I find deals for business class flights from Colorado to Panama?

    Yes. Cheapflights offers flight deals from Colorado to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Panama?

    Currently, April is the cheapest month in which you can book a flight from Colorado to Panama (average of $597). Flying from Colorado to Panama in December is currently the most expensive (average of $765). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Colorado to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Colorado to Panama

Discover the top 3 airlines that operate flights from Colorado to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$464Average$634FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$501Average$699FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$634Average$743FlexibilityNo cancel feeOn-time71%

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